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Ryo Iwamoto

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Vero Cells

Living Beings

Physiology

Phenomena

Genes & Molecular Sequences

Amino Acid Sequence

Concepts & Ideas

Molecular Sequence Data

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Co-Publications
Name
28
Mekada, Eisuke
5
Higashiyama, Shigeki
3
Handa, Kazuyo
3
Mizushima, Hiroto
3
Umata, Toshiyuki
3
Hasuwa, Hidetoshi
2
Yamazaki, Satoru
2
Yoneda, Yoshihiro
2
Taniguchi, Naoyuki
2
Tsuneoka, Makoto
2
Miura, Yoshiki
2
Miyado, Kenji
2
Miyamoto, Shingo
2
Nanba, Daisuke
2
Takahashi, Toshifumi

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Publications

TOP 3
Minami Seigo; Iwamoto Ryo; Mekada Eisuke
HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development.
Morimatsu Miki; Takagi Hiroaki; Ota Kosuke G; Iwamoto Ryo; Yanagida Toshio; Sako Yasushi
Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.
Xie Huirong; Wang Haibin; Tranguch Susanne; Iwamoto Ryo; Mekada Eisuke; Demayo Francesco J; Lydon John P; Das Sanjoy K; Dey Sudhansu K
Maternal heparin-binding-EGF deficiency limits pregnancy success in mice.

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All Publications

2008: Minami Seigo; Iwamoto Ryo; Mekada Eisuke
HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(1):247-58.
2007: Morimatsu Miki; Takagi Hiroaki; Ota Kosuke G; Iwamoto Ryo; Yanagida Toshio; Sako Yasushi
Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):18013-8.
2007: Xie Huirong; Wang Haibin; Tranguch Susanne; Iwamoto Ryo; Mekada Eisuke; Demayo Francesco J; Lydon John P; Das Sanjoy K; Dey Sudhansu K
Maternal heparin-binding-EGF deficiency limits pregnancy success in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):18315-20.
2007: Kageyama Takuya; Ohishi Minako; Miyamoto Shingo; Mizushima Hiroto; Iwamoto Ryo; Mekada Eisuke
Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
Journal of biochemistry 2007;142(1):95-104.
2006: Wang Xiaobiao; Mizushima Hiroto; Adachi Satoshi; Ohishi Minako; Iwamoto Ryo; Mekada Eisuke
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Cell structure and function 2006;31(1):15-27.
2006: Iwamoto Ryo; Mekada Eisuke
ErbB and HB-EGF signaling in heart development and function.
Cell structure and function 2006;31(1):1-14.
2005: Mine Naoki; Iwamoto Ryo; Mekada Eisuke
HB-EGF promotes epithelial cell migration in eyelid development.
Development (Cambridge, England) 2005;132(19):4317-26.
2005: Shirakata Yuji; Kimura Rina; Nanba Daisuke; Iwamoto Ryo; Tokumaru Sho; Morimoto Chie; Yokota Koichi; Nakamura Masanori; Sayama Koji; Mekada Eisuke; Higashiyama Shigeki; Hashimoto Koji
Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing.
Journal of cell science 2005;118(Pt 11):2363-70.
2005: Yagi H; Miyamoto S; Tanaka Y; Sonoda K; Kobayashi H; Kishikawa T; Iwamoto R; Mekada E; Nakano H
Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer.
British journal of cancer 2005;92(9):1737-45.
2005: Kimura Rina; Iwamoto Ryo; Mekada Eisuke
Soluble form of heparin-binding EGF-like growth factor contributes to retinoic acid-induced epidermal hyperplasia.
Cell structure and function 2005;30(2):35-42.
2004: Takazaki Risa; Shishido Yuji; Iwamoto Ryo; Mekada Eisuke
Suppression of the biological activities of the epidermal growth factor (EGF)-like domain by the heparin-binding domain of heparin-binding EGF-like Growth Factor.
The Journal of biological chemistry 2004;279(45):47335-43.
2003: Yamazaki Satoru; Iwamoto Ryo; Saeki Kazuko; Asakura Masanori; Takashima Seiji; Yamazaki Ayano; Kimura Rina; Mizushima Hiroto; Moribe Hiroki; Higashiyama Shigeki; Endoh Masayuki; Kaneda Yasufumi; Takagi Satoshi; Itami Satoshi; Takeda Naoki; Yamada Gen; Mekada Eisuke
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
The Journal of cell biology 2003;163(3):469-75.
2003: Iwamoto Ryo; Yamazaki Satoru; Asakura Masanori; Takashima Seiji; Hasuwa Hidetoshi; Miyado Kenji; Adachi Satoshi; Kitakaze Masafumi; Hashimoto Koji; Raab Gerhard; Nanba Daisuke; Higashiyama Shigeki; Hori Masatsugu; Klagsbrun Michael; Mekada Eisuke
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3221-6.
2002: Yu Xiaochun; Sharma Kailash D; Takahashi Tsuyoshi; Iwamoto Ryo; Mekada Eisuke
Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling.
Molecular biology of the cell 2002;13(7):2547-57.
2002: Shimizu Toko; Matsuishi Toyojiro; Iwamoto Ryo; Handa Kazuyo; Yoshioka Hiroshi; Kato Hirohisa; Ueda Shigeharu; Hara Hideo; Tabira Takeshi; Mekada Eisuke
Elevated levels of anti-CD9 antibodies in the cerebrospinal fluid of patients with subacute sclerosing panencephalitis.
The Journal of infectious diseases 2002;185(9):1346-50.
2001: Hirata M; Umata T; Takahashi T; Ohnuma M; Miura Y; Iwamoto R; Mekada E
Identification of serum factor inducing ectodomain shedding of proHB-EGF and sStudies of noncleavable mutants of proHB-EGF.
Biochemical and biophysical research communications 2001;283(4):915-22.
2001: Nakamura Y; Handa K; Iwamoto R; Tsukamoto T; Takahasi M; Mekada E
Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(4):439-44.
2000: Baba I; Shirasawa S; Iwamoto R; Okumura K; Tsunoda T; Nishioka M; Fukuyama K; Yamamoto K; Mekada E; Sasazuki T
Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.
Cancer research 2000;60(24):6886-9.
2000: Iwamoto R; Mekada E
Heparin-binding EGF-like growth factor: a juxtacrine growth factor.
Cytokine & growth factor reviews 2000;11(4):335-44.
2000: Saeki K; Suzuki H; Tsuneoka M; Maeda M; Iwamoto R; Hasuwa H; Shida S; Takahashi T; Sakaguchi M; Endo T; Miura Y; Mekada E; Mihara K
Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane.
The Journal of biological chemistry 2000;275(41):31996-2002.
1999: Iwamoto R; Handa K; Mekada E
Contact-dependent growth inhibition and apoptosis of epidermal growth factor (EGF) receptor-expressing cells by the membrane-anchored form of heparin-binding EGF-like growth factor.
The Journal of biological chemistry 1999;274(36):25906-12.
1998: Izumi Y; Hirata M; Hasuwa H; Iwamoto R; Umata T; Miyado K; Tamai Y; Kurisaki T; Sehara-Fujisawa A; Ohno S; Mekada E
A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
The EMBO journal 1998;17(24):7260-72.
1996: Nakamura Y; Iwamoto R; Mekada E
Expression and distribution of CD9 in myelin of the central and peripheral nervous systems.
The American journal of pathology 1996;149(2):575-83.
1995: Nakamura K; Iwamoto R; Mekada E
Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
The Journal of cell biology 1995;129(6):1691-705.
1995: Higashiyama S; Iwamoto R; Goishi K; Raab G; Taniguchi N; Klagsbrun M; Mekada E
The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.
The Journal of cell biology 1995;128(5):929-38.
1994: Iwamoto R; Higashiyama S; Mitamura T; Taniguchi N; Klagsbrun M; Mekada E
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity.
The EMBO journal 1994;13(10):2322-30.
1992: Mitamura T; Iwamoto R; Umata T; Yomo T; Urabe I; Tsuneoka M; Mekada E
The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells.
The Journal of cell biology 1992;118(6):1389-99.
1991: Iwamoto R; Senoh H; Okada Y; Uchida T; Mekada E
An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor.
The Journal of biological chemistry 1991;266(30):20463-9.
1991: Mekada E; Senoh H; Iwamoto R; Okada Y; Uchida T
Purification of diphtheria toxin receptor from Vero cells.
The Journal of biological chemistry 1991;266(30):20457-62.
1988: Yoneda Y; Imamoto-Sonobe N; Matsuoka Y; Iwamoto R; Kiho Y; Uchida T
Antibodies to Asp-Asp-Glu-Asp can inhibit transport of nuclear proteins into the nucleus.
Science (New York, N.Y.) 1988;242(4876):275-8.
1988: Imamoto-Sonobe N; Yoneda Y; Iwamoto R; Sugawa H; Uchida T
ATP-dependent association of nuclear proteins with isolated rat liver nuclei.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(10):3426-30.

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