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Alfred Ayala

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Co-Publications
Name
136
Chaudry, Irshad
56
Chung, Chun-Shiang
33
Cioffi, William
23
Angele, Martin
19
Lomas-Neira, Joanne
19
Zellweger, R
18
Grutkoski, Patricia
18
Bland, Kirby
17
Wichmann, MW
17
Wang, Ping
14
Schwacha, Martin
13
Perl, Mario
12
Simms, Hank
10
Knöferl, Markus
10
Ba, Zheng

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Publications

TOP 3
Venet Fabienne; Chung Chun-Shiang; Huang Xin; Lomas-Neira Joanne; Chen Yaping; Ayala Alfred
Lymphocytes in the development of lung inflammation: a role for regulatory CD4+ T cells in indirect pulmonary lung injury.
Huang Xin; Venet Fabienne; Wang Yvonne L; Lepape Alain; Yuan Zhenglong; Chen Yaping; Swan Ryan; Kherouf Hakim; Monneret Guillaume; Chung Chun-Shiang; Ayala Alfred
PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis.
Elphick Gwendolyn F; Sarangi Pranita P; Hyun Young-Min; Hollenbaugh Joseph A; Ayala Alfred; Biffl Walter L; Chung Hung-Li; Rezaie Alireza R; McGrath James L; Topham David J; Reichner Jonathan S; Kim Minsoo
Recombinant human activated protein C inhibits integrin-mediated neutrophil migration.

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All Publications

2009: Venet Fabienne; Chung Chun-Shiang; Huang Xin; Lomas-Neira Joanne; Chen Yaping; Ayala Alfred
Lymphocytes in the development of lung inflammation: a role for regulatory CD4+ T cells in indirect pulmonary lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3472-80.
2009: Huang Xin; Venet Fabienne; Wang Yvonne L; Lepape Alain; Yuan Zhenglong; Chen Yaping; Swan Ryan; Kherouf Hakim; Monneret Guillaume; Chung Chun-Shiang; Ayala Alfred
PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6303-8.
2009: Elphick Gwendolyn F; Sarangi Pranita P; Hyun Young-Min; Hollenbaugh Joseph A; Ayala Alfred; Biffl Walter L; Chung Hung-Li; Rezaie Alireza R; McGrath James L; Topham David J; Reichner Jonathan S; Kim Minsoo
Recombinant human activated protein C inhibits integrin-mediated neutrophil migration.
Blood 2009;113(17):4078-85.
2009: Venet Fabienne; Chung Chun-Shiang; Kherouf Hakim; Geeraert Anne; Malcus Chistophe; Poitevin Françoise; Bohé Julien; Lepape Alain; Ayala Alfred; Monneret Guillaume
Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients.
Intensive care medicine 2009;35(4):678-86.
2009: Hu Caroline K; Venet Fabienne; Heffernan David S; Wang Yvonne L; Horner Brian; Huang Xin; Chung Chun-Shiang; Gregory Stephen H; Ayala Alfred
The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2467-75.
2008: Ward Nicholas S; Casserly Brian; Ayala Alfred
The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients.
Clinics in chest medicine 2008;29(4):617-25, viii.
2008: Perl Mario; Lomas-Neira Joanne; Chung Chun-Shiang; Ayala Alfred
Epithelial cell apoptosis and neutrophil recruitment in acute lung injury-a unifying hypothesis? What we have learned from small interfering RNAs.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):465-75.
2008: Venet Fabienne; Chung Chun-Shiang; Monneret Guillaume; Huang Xin; Horner Brian; Garber Megan; Ayala Alfred
Regulatory T cell populations in sepsis and trauma.
Journal of leukocyte biology 2008;83(3):523-35.
2008: Ayala Alfred; Perl Mario; Venet Fabienne; Lomas-Neira Joanne; Swan Ryan; Chung Chun-Shiang
Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets.
Current pharmaceutical design 2008;14(19):1853-9.
2008: Wesche-Soldato Doreen E; Lomas-Neira Joanne; Perl Mario; Chung Chun-Shiang; Ayala Alfred
Hydrodynamic delivery of siRNA in a mouse model of sepsis.
Methods in molecular biology (Clifton, N.J.) 2008;442():67-73.
2007: Lomas-Neira Joanne L; Ayala Alfred
CXCL2 polymorphism in sepsis and acute respiratory distress syndrome: pathological significance lost in translation.
Critical care medicine 2007;35(10):2439-40.
2007: Perl Mario; Chung Chun-Shiang; Perl Ulrike; Lomas-Neira Joanne; de Paepe Monique; Cioffi William G; Ayala Alfred
Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury.
American journal of respiratory and critical care medicine 2007;176(6):591-601.
2007: Swan Ryan; Chung Chun-Shiang; Albina Jorge; Cioffi William; Perl Mario; Ayala Alfred
Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages.
Surgery 2007;142(2):253-61.
2007: Huang Xin; Venet Fabienne; Chung Chun-Shiang; Lomas-Neira Joanne; Ayala Alfred
Changes in dendritic cell function in the immune response to sepsis. Cell- & tissue-based therapy.
Expert opinion on biological therapy 2007;7(7):929-38.
2007: Wesche-Soldato Doreen E; Chung Chun-Shiang; Gregory Stephen H; Salazar-Mather Thais P; Ayala Carol A; Ayala Alfred
CD8+ T cells promote inflammation and apoptosis in the liver after sepsis: role of Fas-FasL.
The American journal of pathology 2007;171(1):87-96.
2007: Chung Chun-Shiang; Chen Yaping; Grutkoski Patricia S; Doughty Lesley; Ayala Alfred
SOCS-1 is a central mediator of steroid-increased thymocyte apoptosis and decreased survival following sepsis.
Apoptosis : an international journal on programmed cell death 2007;12(7):1143-53.
2007: Perl Mario; Chung Chun-Shiang; Perl Ulrike; Biffl Walter L; Cioffi William G; Ayala Alfred
Beneficial versus detrimental effects of neutrophils are determined by the nature of the insult.
Journal of the American College of Surgeons 2007;204(5):840-52; discussion 852-3.
2007: Wesche-Soldato Doreen E; Swan Ryan Z; Chung Chun-Shiang; Ayala Alfred
The apoptotic pathway as a therapeutic target in sepsis.
Current drug targets 2007;8(4):493-500.
2007: Wisnoski Nicholas; Chung Chun-Shiang; Chen Yaping; Huang Xin; Ayala Alfred
The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis.
Shock (Augusta, Ga.) 2007;27(3):251-7.
2007: Ayala Alfred; Wesche-Soldato Doreen E; Perl Mario; Lomas-Neira Joanne L; Swan Ryan; Chung Chun-Shiang
Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis.
Novartis Foundation symposium 2007;280():37-49; discussion 49-52, 160-4.
2006: Chung Chun-Shiang; Watkins Lara; Funches Antonio; Lomas-Neira Joanne; Cioffi William G; Ayala Alfred
Deficiency of gammadelta T lymphocytes contributes to mortality and immunosuppression in sepsis.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(5):R1338-43.
2006: Doughty Lesley A; Carlton Stacey; Galen Benjamin; Cooma-Ramberan Indranie; Chung Chung-Shiang; Ayala Alfred
Activation of common antiviral pathways can potentiate inflammatory responses to septic shock.
Shock (Augusta, Ga.) 2006;26(2):187-94.
2006: Ayala Alfred; Wesche-Soldato Doreen E; Garber Megan; Swan Ryan; Perl Mario
No good deed goes unpunished!
Intensive care medicine 2006;32(5):637-8.
2006: Lomas-Neira Joanne; Chung Chun-Shiang; Perl Mario; Gregory Stephen; Biffl Walter; Ayala Alfred
Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L51-8.
2006: Perl Mario; Chung Chun-Shiang; Garber Megan; Huang Xin; Ayala Alfred
Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis.
Frontiers in bioscience : a journal and virtual library 2006;11():272-99.
2005: Perl Mario; Chung Chun-Shiang; Ayala Alfred
Apoptosis.
Critical care medicine 2005;33(12 Suppl):S526-9.
2005: Perl Mario; Chung Chun-Shiang; Lomas-Neira Joanne; Rachel Tina-Marie; Biffl Walter L; Cioffi William G; Ayala Alfred
Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.
The American journal of pathology 2005;167(6):1545-59.
2005: Lomas-Neira Joanne; Ayala Alfred
Pepducins: an effective means to inhibit GPCR signaling by neutrophils.
Trends in immunology 2005;26(12):619-21.
2005: Song Grace Y; Chung Chun-Shiang; Rhee Rebecca J; Cioffi William G; Ayala Alfred
Loss of signal transducer and activator of transduction 4 or 6 signaling contributes to immune cell morbidity and mortality in sepsis.
Intensive care medicine 2005;31(11):1564-9.
2005: Wesche-Soldato Doreen E; Chung Chun-Shiang; Lomas-Neira Joanne; Doughty Lesley A; Gregory Stephen H; Ayala Alfred
In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice.
Blood 2005;106(7):2295-301.
2005: Lomas-Neira Joanne; Chung Chun-Shiang; Grutkoski Patricia S; Dunican AnnMarie; Simms H Hank; Cioffi William G; Ayala Alfred
Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury.
Cytokine 2005;31(3):169-79.
2005: Wesche Doreen E; Lomas-Neira Joanne L; Perl Mario; Chung Chun-Shiang; Ayala Alfred
Leukocyte apoptosis and its significance in sepsis and shock.
Journal of leukocyte biology 2005;78(2):325-37.
2005: Lomas-Neira Joanne L; Chung Chun-Shiang; Wesche Doreen E; Perl Mario; Ayala Alfred
In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury.
Journal of leukocyte biology 2005;77(6):846-53.
2005: Wesche-Soldato Doreen E; Lomas-Neira Joanne L; Perl Mario; Jones Leslie; Chung Chun-Shiang; Ayala Alfred
The role and regulation of apoptosis in sepsis.
Journal of endotoxin research 2005;11(6):375-82.
2004: Ding Yanli; Chung Chun-Shiang; Newton Sarah; Chen Yaping; Carlton Stacey; Albina Jorge E; Ayala Alfred
Polymicrobial sepsis induces divergent effects on splenic and peritoneal dendritic cell function in mice.
Shock (Augusta, Ga.) 2004;22(2):137-44.
2004: Lomas-Neira Joanne L; Chung Chun-Shiang; Grutkoski Patricia S; Miller Edmund J; Ayala Alfred
CXCR2 inhibition suppresses hemorrhage-induced priming for acute lung injury in mice.
Journal of leukocyte biology 2004;76(1):58-64.
2004: Grutkoski Patricia S; Chen Yaping; Chung Chun-Shiang; Cioffi William G; Ayala Alfred
Putative mechanism of hemorrhage-induced leukocyte hyporesponsiveness: induction of suppressor of cytokine signaling-3.
The Journal of trauma 2004;56(4):742-7; discussion 747-8.
2004: Newton Sarah; Ding Yanli; Chung Chun-Shiang; Chen Yaping; Lomas-Neira Joanne L; Ayala Alfred
Sepsis-induced changes in macrophage co-stimulatory molecule expression: CD86 as a regulator of anti-inflammatory IL-10 response.
Surgical infections 2004;5(4):375-83.
2003: Rhee Rebecca J; Carlton Stacey; Lomas Joanne L; Lane Crystal; Brossay Laurent; Cioffi William G; Ayala Alfred
Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction.
The Journal of surgical research 2003;115(1):74-81.
2003: Grutkoski P S; Chen Y; Chung C S; Ayala A
Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes.
Journal of leukocyte biology 2003;74(5):916-22.
2003: Chung Chun-Shiang; Song Grace Y; Lomas Joanne; Simms H Hank; Chaudry Irshad H; Ayala Alfred
Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity.
Journal of leukocyte biology 2003;74(3):344-51.
2003: Ayala Alfred; Chung Chun-Shiang; Grutkoski Patricia S; Song Grace Y
Mechanisms of immune resolution.
Critical care medicine 2003;31(8 Suppl):S558-71.
2003: Grutkoski P S; Graeber C T; Lim Y P; Ayala A; Simms H H
Alpha-defensin 1 (human neutrophil protein 1) as an antichemotactic agent for human polymorphonuclear leukocytes.
Antimicrobial agents and chemotherapy 2003;47(8):2666-8.
2003: Angele Martin K; Nitsch Stefan; Knoferl Markus W; Ayala Alfred; Angele Peter; Schildberg Friedrich W; Jauch Karl W; Chaudry Irshad H
Sex-specific p38 MAP kinase activation following trauma-hemorrhage: involvement of testosterone and estradiol.
American journal of physiology. Endocrinology and metabolism 2003;285(1):E189-96.
2003: Lomas Joanne L; Chung Chun-Shiang; Grutkoski Patricia S; LeBlanc Brian W; Lavigne Liz; Reichner Jonathan; Gregory Stephen H; Doughty Lesley A; Cioffi William G; Ayala Alfred
Differential effects of macrophage inflammatory chemokine-2 and keratinocyte-derived chemokine on hemorrhage-induced neutrophil priming for lung inflammation: assessment by adoptive cells transfer in mice.
Shock (Augusta, Ga.) 2003;19(4):358-65.
2003: Ayala Alfred; Lomas Joanne L; Grutkoski Patricia S; Chung Chun-Shiang
Pathological aspects of apoptosis in severe sepsis and shock?
The international journal of biochemistry & cell biology 2003;35(1):7-15.
2003: Ayala Alfred; Lomas Joanne L; Grutkoski Patricia S; Chung Shiang
Fas-ligand mediated apoptosis in severe sepsis and shock.
Scandinavian journal of infectious diseases 2003;35(9):593-600.
2002: Ayala Alfred; Chung Chun-Shiang; Lomas Joanne L; Song Grace Y; Doughty Lesley A; Gregory Stephen H; Cioffi William G; LeBlanc Brian W; Reichner Jonathan; Simms H Hank; Grutkoski Patricia S
Shock-induced neutrophil mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency.
The American journal of pathology 2002;161(6):2283-94.
2002: Song Grace Y; Chung Chun-Shiang; Jarrar Doraid; Cioffi William G; Ayala Alfred
Mechanism of immune dysfunction in sepsis: inducible nitric oxide-meditated alterations in p38 MAPK activation.
The Journal of trauma 2002;53(2):276-82; discussion 282-3.
2002: Grutkoski Patricia S; D'Amico Ron; Ayala Alfred; Simms H Hank
Tumor necrosis factor-alpha-stimulated polymorphonuclear leukocytes suppress migration and bactericidal activity of polymorphonuclear leukocytes in a paracrine manner.
Critical care medicine 2002;30(3):591-7.
2002: Schwacha Martin G; Chung Chun-Shiang; Ayala Alfred; Bland Kirby I; Chaudry Irshad H
Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury.
American journal of physiology. Cell physiology 2002;282(2):C263-70.
2002: Yang Shaolong; Chung Chun-Shiang; Ayala Alfred; Chaudry Irshad H; Wang Ping
Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse.
Shock (Augusta, Ga.) 2002;17(1):55-60.
2002: Grutkoski Patricia S; Graeber C Thomas; Ayala Alfred; Simms H Hank
Paracrine suppression of apoptosis by cytokine-stimulated neutrophils involves divergent regulation of NF-kappaB, Bcl-X(L), and Bak.
Shock (Augusta, Ga.) 2002;17(1):47-54.
2002: Knöferl Markus W; Angele Martin K; Diodato Michael D; Schwacha Martin G; Ayala Alfred; Cioffi William G; Bland Kirby I; Chaudry Irshad H
Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis.
Annals of surgery 2002;235(1):105-12.
2001: Angele M K; Knöferl M W; Ayala A; Bland K I; Chaudry I H
Testosterone and estrogen differently effect Th1 and Th2 cytokine release following trauma-haemorrhage.
Cytokine 2001;16(1):22-30.
2001: Knöferl M W; Jarrar D; Angele M K; Ayala A; Schwacha M G; Bland K I; Chaudry I H
17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage.
American journal of physiology. Cell physiology 2001;281(4):C1131-8.
2001: Chung C S; Wang W; Chaudry I H; Ayala A
Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(5):G812-8.
2001: Ayala A; Chung C S; Song G Y; Chaudry I H
IL-10 mediation of activation-induced TH1 cell apoptosis and lymphoid dysfunction in polymicrobial sepsis.
Cytokine 2001;14(1):37-48.
2001: Song G Y; Chung C S; Jarrar D; Chaudry I H; Ayala A
Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis.
Shock (Augusta, Ga.) 2001;15(1):42-8.
2000: Dunican A L; Leuenroth S J; Grutkoski P; Ayala A; Simms H H
TNFalpha-induced suppression of PMN apoptosis is mediated through interleukin-8 production.
Shock (Augusta, Ga.) 2000;14(3):284-8; discussion 288-9.
2000: Angele M K; Fitzal F; Smail N; Knöferl M W; Schwacha M G; Ayala A; Wang P; Chaudry I H
L-arginine attenuates trauma-hemorrhage-induced liver injury.
Critical care medicine 2000;28(9):3242-8.
2000: Ayala A; Song G Y; Chung C S; Redmond K M; Chaudry I H
Immune depression in polymicrobial sepsis: the role of necrotic (injured) tissue and endotoxin.
Critical care medicine 2000;28(8):2949-55.
2000: Angele M K; Schwacha M G; Ayala A; Chaudry I H
Effect of gender and sex hormones on immune responses following shock.
Shock (Augusta, Ga.) 2000;14(2):81-90.
2000: Leuenroth S J; Grutkoski P S; Ayala A; Simms H H
Suppression of PMN apoptosis by hypoxia is dependent on Mcl-1 and MAPK activity.
Surgery 2000;128(2):171-7.
2000: Song G Y; Chung C S; Chaudry I H; Ayala A
IL-4-induced activation of the Stat6 pathway contributes to the suppression of cell-mediated immunity and death in sepsis.
Surgery 2000;128(2):133-8.
2000: Leuenroth S J; Grutkoski P S; Ayala A; Simms H H
The loss of Mcl-1 expression in human polymorphonuclear leukocytes promotes apoptosis.
Journal of leukocyte biology 2000;68(1):158-66.
2000: Chung C S; Song G Y; Moldawer L L; Chaudry I H; Ayala A
Neither Fas ligand nor endotoxin is responsible for inducible peritoneal phagocyte apoptosis during sepsis/peritonitis.
The Journal of surgical research 2000;91(2):147-53.
2000: Song G Y; Chung C S; Chaudry I H; Ayala A
Immune suppression in polymicrobial sepsis: differential regulation of Th1 and Th2 responses by p38 MAPK.
The Journal of surgical research 2000;91(2):141-6.
2000: Chung C S; Song G Y; Wang W; Chaudry I H; Ayala A
Septic mucosal intraepithelial lymphoid immune suppression: role for nitric oxide not interleukin-10 or transforming growth factor-beta.
The Journal of trauma 2000;48(5):807-12; discussion 812-3.
2000: Schwacha M G; Ayala A; Chaudry I H
Insights into the role of gammadelta T lymphocytes in the immunopathogenic response to thermal injury.
Journal of leukocyte biology 2000;67(5):644-50.
2000: Dunican A; Grutkoski P; Leuenroth S; Ayala A; Simms H H
Neutrophils regulate their own apoptosis via preservation of CXC receptors.
The Journal of surgical research 2000;90(1):32-8.
2000: Knöferl M W; Diodato M D; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Do female sex steroids adversely or beneficially affect the depressed immune responses in males after trauma-hemorrhage?
Archives of surgery (Chicago, Ill. : 1960) 2000;135(4):425-33.
2000: Dunican A L; Leuenroth S J; Ayala A; Simms H H
CXC chemokine suppression of polymorphonuclear leukocytes apoptosis and preservation of function is oxidative stress independent.
Shock (Augusta, Ga.) 2000;13(3):244-50.
2000: Kahlke V; Angele M K; Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Reversal of sexual dimorphism in splenic T lymphocyte responses after trauma-hemorrhage with aging.
American journal of physiology. Cell physiology 2000;278(3):C509-16.
2000: Wichmann M W; Zellweger R; Ayala A; Chaudry I H
Effect of naloxone on immune responses after hemorrhagic shock.
Critical care medicine 2000;28(1):184-9.
2000: Kahlke V; Angele M K; Ayala A; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
Immune dysfunction following trauma-haemorrhage: influence of gender and age.
Cytokine 2000;12(1):69-77.
1999: Grutkoski P S; D'Amico R; Ayala A; Simms H H
IL-1beta stimulation induces paracrine regulation of PMN function and apoptosis.
Shock (Augusta, Ga.) 1999;12(5):373-81.
1999: Angele M K; Xu Y X; Ayala A; Schwacha M G; Catania R K; Cioffi W G; Bland K I; Chaudry I H
Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis.
Shock (Augusta, Ga.) 1999;12(4):316-22.
1999: Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Role of protein kinase C in cyclic AMP-mediated suppression of T-lymphocyte activation following burn injury.
Biochimica et biophysica acta 1999;1455(1):45-53.
1999: Song G Y; Chung C S; Chaudry I H; Ayala A
What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant?
Surgery 1999;126(2):378-83.
1999: Angele M K; Knöferl M W; Ayala A; Albina J E; Cioffi W G; Bland K I; Chaudry I H
Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site.
Surgery 1999;126(2):279-85.
1999: Angele M K; Knöferl M W; Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage.
The American journal of physiology 1999;277(1 Pt 1):C35-42.
1999: Catania R A; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Dehydroepiandrosterone restores immune function following trauma-haemorrhage by a direct effect on T lymphocytes.
Cytokine 1999;11(6):443-50.
1999: Ayala A; Chung C S; Xu Y X; Evans T A; Redmond K M; Chaudry I H
Increased inducible apoptosis in CD4+ T lymphocytes during polymicrobial sepsis is mediated by Fas ligand and not endotoxin.
Immunology 1999;97(1):45-55.
1999: Angele M K; Knöferl M W; Schwacha M G; Ayala A; Bland K I; Cioffi W G; Josephson S L; Chaudry I H
Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: a possible mechanism for increased wound infection.
Annals of surgery 1999;229(5):651-60; discussion 660-1.
1999: Song G Y; Chung C S; Schwacha M G; Jarrar D; Chaudry I H; Ayala A
Splenic immune suppression in sepsis: A role for IL-10-induced changes in P38 MAPK signaling.
The Journal of surgical research 1999;83(1):36-43.
1999: Ayala A; Xu Y X; Chung C S; Chaudry I H
Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?
Shock (Augusta, Ga.) 1999;11(3):211-7.
1999: Angele M K; Schwacha M G; Smail N; Catania R A; Ayala A; Cioffi W G; Chaudry I H
Hypoxemia in the absence of blood loss upregulates iNOS expression and activity in macrophages.
The American journal of physiology 1999;276(2 Pt 1):C285-90.
1999: Angele M K; Smail N; Ayala A; Cioffi W G; Bland K I; Chaudry I H
L-arginine: a unique amino acid for restoring the depressed macrophage functions after trauma-hemorrhage.
The Journal of trauma 1999;46(1):34-41.
1999: Knöferl M W; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Do different rates of fluid resuscitation adversely or beneficially influence immune responses after trauma-hemorrhage?
The Journal of trauma 1999;46(1):23-33.
1999: Angele M K; Smail N; Knöferl M W; Ayala A; Cioffi W G; Chaudry I H
L-Arginine restores splenocyte functions after trauma and hemorrhage potentially by improving splenic blood flow.
The American journal of physiology 1999;276(1 Pt 1):C145-51.
1998: Angele M K; Catania R A; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Dehydroepiandrosterone: an inexpensive steroid hormone that decreases the mortality due to sepsis following trauma-induced hemorrhage.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(12):1281-8.
1998: Chung C S; Xu Y X; Wang W; Chaudry I H; Ayala A
Is Fas ligand or endotoxin responsible for mucosal lymphocyte apoptosis in sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1998;133(11):1213-20.
1998: Wichmann M W; Ayala A; Chaudry I H
Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock.
Critical care medicine 1998;26(8):1372-8.
1998: Chung C S; Xu Y X; Chaudry I H; Ayala A
Sepsis induces increased apoptosis in lamina propria mononuclear cells which is associated with altered cytokine gene expression.
The Journal of surgical research 1998;77(1):63-70.
1998: Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Testosterone: the culprit for producing splenocyte immune depression after trauma hemorrhage.
The American journal of physiology 1998;274(6 Pt 1):C1530-6.
1998: Samy T S; Ayala A; Catania R A; Chaudry I H
Trauma-hemorrhage activates signal transduction pathways in mouse splenic T cells.
Shock (Augusta, Ga.) 1998;9(6):443-50.
1998: Ayala A; Evans T A; Chaudry I H
Does hepatocellular injury in sepsis involve apoptosis?
The Journal of surgical research 1998;76(2):165-73.
1998: Xu Y X; Ayala A; Chaudry I H
Prolonged immunodepression after trauma and hemorrhagic shock.
The Journal of trauma 1998;44(2):335-41.
1998: Ayala A; Xin Xu Y; Ayala C A; Sonefeld D E; Karr S M; Evans T A; Chaudry I H
Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process.
Blood 1998;91(4):1362-72.
1998: Angele M K; Ayala A; Monfils B A; Cioffi W G; Bland K I; Chaudry I H
Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage.
The Journal of trauma 1998;44(1):78-85.
1998: Zellweger R; Wichmann M W; Ayala A; Chaudry I H
Metoclopramide: a novel and safe immunomodulating agent for restoring the depressed macrophage immune function after hemorrhage.
The Journal of trauma 1998;44(1):70-7.
1997: Molnar R G; Wang P; Ayala A; Ganey P E; Roth R A; Chaudry I H
The role of neutrophils in producing hepatocellular dysfunction during the hyperdynamic stage of sepsis in rats.
The Journal of surgical research 1997;73(2):117-22.
1997: Angele M K; Wichmann M W; Ayala A; Cioffi W G; Chaudry I H
Testosterone receptor blockade after hemorrhage in males. Restoration of the depressed immune functions and improved survival following subsequent sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(11):1207-14.
1997: Wichmann M W; Ayala A; Chaudry I H
Male sex steroids are responsible for depressing macrophage immune function after trauma-hemorrhage.
The American journal of physiology 1997;273(4 Pt 1):C1335-40.
1997: Wichmann M W; Angele M K; Ayala A; Cioffi W G; Chaudry I H
Flutamide: a novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock.
Shock (Augusta, Ga.) 1997;8(4):242-8.
1997: Williams T E; Ayala A; Chaudry I H
Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release.
The Journal of surgical research 1997;70(2):113-8.
1997: Xu Y X; Ayala A; Monfils B; Cioffi W G; Chaudry I H
Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: increased apoptosis associated with elevated Fas expression in Peyer's patches.
The Journal of surgical research 1997;70(1):55-60.
1997: Zhu X H; Zellweger R; Wichmann M W; Ayala A; Chaudry I H
Effects of prolactin and metoclopramide on macrophage cytokine gene expression in late sepsis.
Cytokine 1997;9(6):437-46.
1997: Ayala A; O'Neill P J; Uebele S A; Herdon C D; Chaudry I H
Mechanism of splenic immunosuppression during sepsis: key role of Kupffer cell mediators.
The Journal of trauma 1997;42(5):882-8.
1997: Ayala A; Karr S M; Evans T A; Chaudry I H
Factors responsible for peritoneal granulocyte apoptosis during sepsis.
The Journal of surgical research 1997;69(1):67-75.
1997: Xu Y X; Wichmann M W; Ayala A; Cioffi W G; Chaudry I H
Trauma-hemorrhage induces increased thymic apoptosis while decreasing IL-3 release and increasing GM-CSF.
The Journal of surgical research 1997;68(1):24-30.
1997: Zellweger R; Wichmann M W; Ayala A; Stein S; DeMaso C M; Chaudry I H
Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males.
Critical care medicine 1997;25(1):106-10.
1996: Zellweger R; Zhu X H; Wichmann M W; Ayala A; DeMaso C M; Chaudry I H
Prolactin administration following hemorrhagic shock improves macrophage cytokine release capacity and decreases mortality from subsequent sepsis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5748-54.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Enhanced immune responses in females, as opposed to decreased responses in males following haemorrhagic shock and resuscitation.
Cytokine 1996;8(11):853-63.
1996: Ayala A; Tu Y; Flye M W; Chaudry I H
Depressed splenic function after hemorrhage results from gastrointestinal tract stimulation of hepatic-mediator release. Correction with portacaval shunt.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(11):1209-14; discussion 1215.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(11):1186-91; discussion 1191-2.
1996: Wichmann M W; Haisken J M; Ayala A; Chaudry I H
Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge.
The Journal of surgical research 1996;65(2):109-14.
1996: Wichmann M W; Arnoczky S P; DeMaso C M; Ayala A; Chaudry I H
Depressed osteoblast activity and increased osteocyte necrosis after closed bone fracture and hemorrhagic shock.
The Journal of trauma 1996;41(4):628-33.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Williams C; Chaudry I H
Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(9):995-1000.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Increased melatonin levels after hemorrhagic shock in male and female C3H/HeN mice.
Experientia 1996;52(6):587-90.
1996: Wichmann M W; Zellweger R; DeMaso; Ayala A; Chaudry I H
Melatonin administration attenuates depressed immune functions trauma-hemorrhage.
The Journal of surgical research 1996;63(1):256-62.
1996: Zellweger R; Wichmann M W; Ayala A; DeMaso C M; Chaudry I H
Prolactin: a novel and safe immunomodulating hormone for the treatment of immunodepression following severe hemorrhage.
The Journal of surgical research 1996;63(1):53-8.
1996: Ayala A; Chaudry I H
Platelet activating factor and its role in trauma, shock, and sepsis.
New horizons (Baltimore, Md.) 1996;4(2):265-75.
1996: Ayala A; Herdon C D; Lehman D L; Ayala C A; Chaudry I H
Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators.
Blood 1996;87(10):4261-75.
1996: Ayala A; Urbanich M A; Herdon C D; Chaudry I H
Is sepsis-induced apoptosis associated with macrophage dysfunction?
The Journal of trauma 1996;40(4):568-73; discussion 573-4.
1996: Zhu X H; Zellweger R; Ayala A; Chaudry I H
Prolactin inhibits the increased cytokine gene expression in Kupffer cells following haemorrhage.
Cytokine 1996;8(2):134-40.
1996: Ayala A; Chaudry I H
Immune dysfunction in murine polymicrobial sepsis: mediators, macrophages, lymphocytes and apoptosis.
Shock (Augusta, Ga.) 1996;6 Suppl 1():S27-38.
1995: Ayala A; Deol Z K; Lehman D L; Herdon C D; Chaudry I H
Does endotoxin play a major role in inducing the depression of macrophage function during polymicrobial sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1995;130(11):1178-84; discussion 1184-5.
1995: Zellweger R; Ayala A; Zhu X L; Morrison M H; Chaudry I H
Effect of surgical trauma on splenocyte and peritoneal macrophage immune function.
The Journal of trauma 1995;39(4):645-50.
1995: Zellweger R; Ayala A; Schmand J F; Morrison M H; Chaudry I H
PAF-antagonist administration after hemorrhage-resuscitation prevents splenocyte immunodepression.
The Journal of surgical research 1995;59(3):366-70.
1995: Zellweger R; Ayala A; DeMaso C M; Chaudry I H
Trauma-hemorrhage causes prolonged depression in cellular immunity.
Shock (Augusta, Ga.) 1995;4(2):149-53.
1995: Ertel W; Morrison M H; Ayala A; Chaudry I H
Hypoxemia in the absence of blood loss or significant hypotension causes inflammatory cytokine release.
The American journal of physiology 1995;269(1 Pt 2):R160-6.
1995: Zellweger R; Ayala A; Zhu X L; Holme K R; DeMaso C M; Chaudry I H
A novel nonanticoagulant heparin improves splenocyte and peritoneal macrophage immune function after trauma-hemorrhage and resuscitation.
The Journal of surgical research 1995;59(1):211-8.
1995: Mayberry A; Ayala A; Chaudry I H
Hemorrhage affects the ability of murine peritoneal macrophages to alkanize intracellular pH in acidic environments.
The Journal of surgical research 1995;58(6):682-6.
1995: Schmand J F; Ayala A; Morrison M H; Chaudry I H
Effects of hydroxyethyl starch after trauma-hemorrhagic shock: restoration of macrophage integrity and prevention of increased circulating interleukin-6 levels.
Critical care medicine 1995;23(5):806-14.
1995: Ayala A; Herdon C D; Lehman D L; DeMaso C M; Ayala C A; Chaudry I H
The induction of accelerated thymic programmed cell death during polymicrobial sepsis: control by corticosteroids but not tumor necrosis factor.
Shock (Augusta, Ga.) 1995;3(4):259-67.
1995: Ayala A; Chaudry I H
Dietary n-3 polyunsaturated fatty acid modulation of immune cell function before or after trauma.
Nutrition (Burbank, Los Angeles County, Calif.) 1995;11(1):1-11.
1995: Zhu X L; Zellweger R; Zhu X H; Ayala A; Chaudry I H
Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage.
Cytokine 1995;7(1):8-14.
1995: Chaudry I H; Zellweger R; Ayala A
The role of bacterial translocation on Kupffer cell immune function following hemorrhage.
Progress in clinical and biological research 1995;392():209-18.
1994: Schmand J F; Ayala A; Morrison M H; Chaudry I H
Dextran 70 administration after trauma-hemorrhagic shock does not impair cellular immune functions.
Journal of critical care 1994;9(4):244-54.
1994: Ayala A; Lehman D L; Herdon C D; Chaudry I H
Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release.
Archives of surgery (Chicago, Ill. : 1960) 1994;129(11):1172-8.
1994: Ertel W; Morrison M H; Ayala A; Chaudry I H
Biological significance of elevated TNF levels: in vivo administration of monoclonal antibody against tnf following haemorrhage shock increases the capacity of macrophages to release TNF while restoring immunoresponsiveness.
Cytokine 1994;6(6):624-32.
1994: Zhu X L; Ayala A; Zellweger R; Morrison M H; Chaudry I H
Peritoneal macrophages show increased cytokine gene expression following haemorrhagic shock.
Immunology 1994;83(3):378-83.
1994: Schmand J F; Ayala A; Chaudry I H
Effects of trauma, duration of hypotension, and resuscitation regimen on cellular immunity after hemorrhagic shock.
Critical care medicine 1994;22(7):1076-83.
1994: Ayala A; Deol Z K; Lehman D L; Herdon C D; Chaudry I H
Polymicrobial sepsis but not low-dose endotoxin infusion causes decreased splenocyte IL-2/IFN-gamma release while increasing IL-4/IL-10 production.
The Journal of surgical research 1994;56(6):579-85.
1994: Lindsey H J; Kisala J M; Ayala A; Lehman D; Herdon C D; Chaudry I H
Pentoxifylline attenuates oxygen-induced lung injury.
The Journal of surgical research 1994;56(6):543-8.
1994: Meldrum D R; Ayala A; Chaudry I H
Energetics of lymphocyte "burnout" in late sepsis: adjuvant treatment with ATP-MgCl2 improves energetics and decreases lethality.
The Journal of surgical research 1994;56(6):537-42.
1994: O'Neill P J; Cobb L M; Ayala A; Morrison M H; Chaudry I H
Aggressive fluid resuscitation following intestinal ischemia-reperfusion in immature rats prevents metabolic derangements and down regulates interleukin-6 release.
Shock (Augusta, Ga.) 1994;1(5):381-7.
1994: Ayala A; Chaudry I H
Hemorrhage induces a reduction in the capacity of macrophages to mobilize intracellular calcium secondary to formyl-methionyl-leucyl-phenylalanine stimulation: association with alterations in cells surface Fc receptor expression and increased prostaglandin release.
Shock (Augusta, Ga.) 1994;1(3):228-35.
1994: Wang P; Ba Z F; Lu M C; Ayala A; Harkema J M; Chaudry I H
Measurement of circulating blood volume in vivo after trauma-hemorrhage and hemodilution.
The American journal of physiology 1994;266(2 Pt 2):R368-74.
1994: O'Neill P J; Ayala A; Wang P; Ba Z F; Morrison M H; Schultze A E; Reich S S; Chaudry I H
Role of Kupffer cells in interleukin-6 release following trauma-hemorrhage and resuscitation.
Shock (Augusta, Ga.) 1994;1(1):43-7.
1993: Zhu X; Ertel W; Ayala A; Morrison M H; Perrin M M; Chaudry I H
Chloroquine inhibits macrophage tumour necrosis factor-alpha mRNA transcription.
Immunology 1993;80(1):122-6.
1993: Meldrum D R; Ayala A; Chaudry I H
Mechanism of diltiazem's immunomodulatory effects after hemorrhage and resuscitation.
The American journal of physiology 1993;265(2 Pt 1):C412-21.
1993: Ayala A; Meldrum D R; Perrin M M; Chaudry I H
The release of transforming growth factor-beta following haemorrhage: its role as a mediator of host immunosuppression.
Immunology 1993;79(3):479-84.
1993: Wang P; Ayala A; Ba Z F; Zhou M; Perrin M M; Chaudry I H
Tumor necrosis factor-alpha produces hepatocellular dysfunction despite normal cardiac output and hepatic microcirculation.
The American journal of physiology 1993;265(1 Pt 1):G126-32.
1993: Ertel W; Singh G; Morrison M H; Ayala A; Chaudry I H
Chemically induced hypotension increases PGE2 release and depresses macrophage antigen presentation.
The American journal of physiology 1993;264(4 Pt 2):R655-60.
1993: Ayala A; Wang P; Chaudry I H
Insights into the mechanism by which interferon-gamma improves macrophage function following hemorrhage and resuscitation.
The Journal of surgical research 1993;54(4):322-7.
1993: Kisala J M; Ayala A; Stephan R N; Chaudry I H
A model of pulmonary atelectasis in rats: activation of alveolar macrophage and cytokine release.
The American journal of physiology 1993;264(3 Pt 2):R610-4.
1993: Ayala A; Knotts J B; Ertèl W; Perrin M M; Morrison M H; Chaudry I H
Role of interleukin 6 and transforming growth factor-beta in the induction of depressed splenocyte responses following sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1993;128(1):89-94; discussion 94-5.
1993: Ertel W; Morrison M H; Ayala A; Chaudry I H
Modulation of macrophage membrane phospholipids by n-3 polyunsaturated fatty acids increases interleukin 1 release and prevents suppression of cellular immunity following hemorrhagic shock.
Archives of surgery (Chicago, Ill. : 1960) 1993;128(1):15-20; discussion 20-1.
1992: Wang P; Ba Z F; Morrison M H; Ayala A; Chaudry I H
Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation.
Surgery 1992;112(2):451-7; discussion 457-8.
1992: Meldrum D R; Ayala A; Chaudry I H
Energetics of defective macrophage antigen presentation after hemorrhage as determined by ultraresolution 31P nuclear magnetic resonance spectrometry: restoration with adenosine triphosphate-MgCl2.
Surgery 1992;112(2):150-6; discussion 156-8.
1992: Ertel W; Morrison M H; Meldrum D R; Ayala A; Chaudry I H
Ibuprofen restores cellular immunity and decreases susceptibility to sepsis following hemorrhage.
The Journal of surgical research 1992;53(1):55-61.
1992: Ayala A; Perrin M M; Wang P; Chaudry I H
Sepsis induces an early increased spontaneous release of hepatocellular stimulatory factor (interleukin-6) by Kupffer cells in both endotoxin tolerant and intolerant mice.
The Journal of surgical research 1992;52(6):635-41.
1992: Wang P; Ba Z F; Morrison M H; Ayala A; Dean R E; Chaudry I H
Mechanism of the beneficial effects of ATP-MgCl2 following trauma-hemorrhage and resuscitation: downregulation of inflammatory cytokine (TNF, IL-6) release.
The Journal of surgical research 1992;52(4):364-71.
1992: Rana M W; Singh G; Wang P; Ayala A; Zhou M; Chaudry I H
Protective effects of preheparinization on the microvasculature during and after hemorrhagic shock.
The Journal of trauma 1992;32(4):420-6.
1992: Ayala A; Perrin M M; Kisala J M; Ertel W; Chaudry I H
Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor).
Circulatory shock 1992;36(3):191-9.
1992: Wang P; Zhou M; Rana M W; Singh G; Ba Z F; Ayala A; Chaudry I H
ATP-MgCl2 restores renal microcirculation following trauma and severe hemorrhage.
Canadian journal of physiology and pharmacology 1992;70(3):349-57.
1992: Wang P; Ba Z F; Ayala A; Chaudry I H
Hepatocellular dysfunction persists during early sepsis despite increased volume of crystalloid resuscitation.
The Journal of trauma 1992;32(3):389-96; discussion 396-7.
1992: Ertel W; Morrison M H; Ayala A; Dean R E; Chaudry I H
Interferon-gamma attenuates hemorrhage-induced suppression of macrophage and splenocyte functions and decreases susceptibility to sepsis.
Surgery 1992;111(2):177-87.
1992: Ayala A; Kisala J M; Felt J A; Perrin M M; Chaudry I H
Does endotoxin tolerance prevent the release of inflammatory monokines (interleukin 1, interleukin 6, or tumor necrosis factor) during sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1992;127(2):191-6; discussion 196-7.
1992: Ertel W; Morrison M H; Ayala A; Chaudry I H
Chloroquine attenuates hemorrhagic shock-induced immunosuppression and decreases susceptibility to sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1992;127(1):70-5; discussion 75-6.
1992: Ayala A; Perrin M M; Ertel W; Chaudry I H
Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release.
Cytokine 1992;4(1):66-75.
1991: Ayala A; Perrin M M; Wang P; Ertel W; Chaudry I H
Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4147-54.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Chloroquine attenuates hemorrhagic shock-induced suppression of Kupffer cell antigen presentation and major histocompatibility complex class II antigen expression through blockade of tumor necrosis factor and prostaglandin release.
Blood 1991;78(7):1781-8.
1991: Ertel W; Morrison M H; Ayala A; Perrin M M; Chaudry I H
Anti-TNF monoclonal antibodies prevent haemorrhage-induced suppression of Kupffer cell antigen presentation and MHC class II antigen expression.
Immunology 1991;74(2):290-7.
1991: Meldrum D R; Ayala A; Perrin M M; Ertel W; Chaudry I H
Diltiazem restores IL-2, IL-3, IL-6, and IFN-gamma synthesis and decreases host susceptibility to sepsis following hemorrhage.
The Journal of surgical research 1991;51(2):158-64.
1991: Meldrum D R; Ayala A; Wang P; Ertel W; Chaudry I H
Association between decreased splenic ATP levels and immunodepression: amelioration with ATP-MgCl2.
The American journal of physiology 1991;261(2 Pt 2):R351-7.
1991: Ertel W; Morrison M H; Wang P; Ba Z F; Ayala A; Chaudry I H
The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins.
Annals of surgery 1991;214(2):141-8.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Insights into the mechanisms of defective antigen presentation after hemorrhage.
Surgery 1991;110(2):440-5; discussion 445-7.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Eicosanoids regulate tumor necrosis factor synthesis after hemorrhage in vitro and in vivo.
The Journal of trauma 1991;31(5):609-15; discussion 615-6.
1991: Wang P; Ayala A; Dean R E; Hauptman J G; Ba Z F; DeJong G K; Chaudry I H
Adequate crystalloid resuscitation restores but fails to maintain the active hepatocellular function following hemorrhagic shock.
The Journal of trauma 1991;31(5):601-7; discussion 607-8.
1991: Ertel W; Morrison M H; Ayala A; Perrin M M; Chaudry I H
Blockade of prostaglandin production increases cachectin synthesis and prevents depression of macrophage functions after hemorrhagic shock.
Annals of surgery 1991;213(3):265-71.
1991: Ayala A; Wang P; Ba Z F; Perrin M M; Ertel W; Chaudry I H
Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage.
The American journal of physiology 1991;260(1 Pt 2):R167-71.
1990: Rana M W; Ayala A; Dean R E; Chaudry I H
Decreased Fc receptor expression on macrophages following simple hemorrhage as observed by scanning immunoelectron microscopy.
Journal of leukocyte biology 1990;48(6):512-8.
1990: Ertel W; Meldrum D R; Morrison M H; Ayala A; Chaudry I H
Immunoprotective effect of a calcium channel blocker on macrophage antigen presentation function, major histocompatability class II antigen expression, and interleukin-1 synthesis after hemorrhage.
Surgery 1990;108(2):154-9; discussion 159-60.
1990: Ayala A; Perrin M M; Chaudry I H
Defective macrophage antigen presentation following haemorrhage is associated with the loss of MHC class II (Ia) antigens.
Immunology 1990;70(1):33-9.
1990: Ayala A; Perrin M M; Meldrum D R; Ertel W; Chaudry I H
Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin.
Cytokine 1990;2(3):170-4.
1990: Ayala A; Perrin M M; Wagner M A; Chaudry I H
Enhanced susceptibility to sepsis after simple hemorrhage. Depression of Fc and C3b receptor-mediated phagocytosis.
Archives of surgery (Chicago, Ill. : 1960) 1990;125(1):70-4; discussion 74-5.
1989: Stephan R N; Ayala A; Harkema J M; Dean R E; Border J R; Chaudry I H
Mechanism of immunosuppression following hemorrhage: defective antigen presentation by macrophages.
The Journal of surgical research 1989;46(6):553-6.

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