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Atsuko Hikikoshi Iwane

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Keigo Ikezaki; Atsuko Hikikoshi Iwane; Tomotaka Komori; So Nishikawa; Mitsuhiro Sugawa; Yoshiyuki Arai; Toshio Yanagida
Simultaneous observation of the lever arm and head explains myosin VI dual function.
Taro Q P Noguchi; Kiyotaka Tokuraku; Nobuhisa Umeki; Noriyuki Demizu; Kohji Ito; Atsuko Hikikoshi Iwane; Tomotaka Komori; Toshio Yanagida; Taro Q P Uyeda
G146V mutation at the hinge region of actin reveals a myosin class-specific requirement of actin conformations for motility.
Masashi Ohmachi; Fumihiko Fujii; Atsuko Hikikoshi Iwane; Takashi Jin; Yasunori Komori; Toshio Yanagida
Fluorescence microscopy for simultaneous observation of 3D orientation and movement and its application to quantum rod-tagged myosin V.

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2012: Keigo Ikezaki; Atsuko Hikikoshi Iwane; Tomotaka Komori; So Nishikawa; Mitsuhiro Sugawa; Yoshiyuki Arai; Toshio Yanagida
Simultaneous observation of the lever arm and head explains myosin VI dual function.
Small (Weinheim an der Bergstrasse, Germany) 2012;8(19):3035-40.
2012: Taro Q P Noguchi; Kiyotaka Tokuraku; Nobuhisa Umeki; Noriyuki Demizu; Kohji Ito; Atsuko Hikikoshi Iwane; Tomotaka Komori; Toshio Yanagida; Taro Q P Uyeda
G146V mutation at the hinge region of actin reveals a myosin class-specific requirement of actin conformations for motility.
The Journal of biological chemistry 2012;287(29):24339-45.
2012: Masashi Ohmachi; Fumihiko Fujii; Atsuko Hikikoshi Iwane; Takashi Jin; Yasunori Komori; Toshio Yanagida
Fluorescence microscopy for simultaneous observation of 3D orientation and movement and its application to quantum rod-tagged myosin V.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(14):5294-8.
2012: Masatoshi Morimatsu; So Nishikawa; Mitsuhiro Sugawa; Yuichi Togashi; Atsuko Hikikoshi Iwane; Toshio Yanagida
Spontaneous structural changes in actin regulate G-F transformation.
PloS one 2012;7(11):e45864.
2012: Keisuke Fujita; Mitsuhiro Iwaki; Atsuko Hikikoshi Iwane; Lorenzo Marcucci; Toshio Yanagida
Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch.
Nature communications 2012;3():956.
2010: Takashi Fujii; Atsuko Hikikoshi Iwane; Toshio Yanagida; Keiichi Namba
Direct visualization of secondary structures of F-actin by electron cryomicroscopy.
Nature 2010;467(7316):724-8.
2010: Tomonobu M Watanabe; Toshio Yanagida; Atsuko Hikikoshi Iwane
Single molecular observation of self-regulated kinesin motility.
Biochemistry 2010;49(22):4654-61.
2010: Mitsuhiro Sugawa; So Nishikawa; Atsuko Hikikoshi Iwane; Vasudevanpillai Biju; Toshio Yanagida
Single-molecule FRET imaging for enzymatic reactions at high ligand concentrations.
Small (Weinheim an der Bergstrasse, Germany) 2010;6(3):346-50.
2010: Tomonobu M Watanabe; Atsuko Hikikoshi Iwane; Hiroto Tanaka; Mitsuo Ikebe; Toshio Yanagida
Mechanical characterization of one-headed myosin-V using optical tweezers.
PloS one 2010;5(8):e12224.
2009: Atsuko Hikikoshi Iwane; Masatoshi Morimatsu; Toshio Yanagida
Recombinant alpha-actin for specific fluorescent labeling.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2009;85(10):491-9.
2009: Tomotaka Komori; So Nishikawa; Takayuki Ariga; Atsuko Hikikoshi Iwane; Toshio Yanagida
Simultaneous measurement of nucleotide occupancy and mechanical displacement in myosin-V, a processive molecular motor.
Biophysical journal 2009;96(1):L04-6.
2008: Masatoshi Nishikawa; Hiroaki Takagi; Tatsuo Shibata; Atsuko Hikikoshi Iwane; Toshio Yanagida
Fluctuation analysis of mechanochemical coupling depending on the type of biomolecular motors.
Physical review letters 2008;101(12):128103.
2008: Mitsuhiro Iwaki; Atsuko Hikikoshi Iwane; Mitsuo Ikebe; Toshio Yanagida
Biased Brownian motion mechanism for processivity and directionality of single-headed myosin-VI.
Bio Systems 2008;93(1-2):39-47.
2008: Tomotaka Komori; So Nishikawa; Takayuki Ariga; Atsuko Hikikoshi Iwane; Toshio Yanagida
Measurement system for simultaneous observation of myosin V chemical and mechanical events.
Bio Systems 2008;93(1-2):48-57.
2007: Yasunori Komori; Atsuko Hikikoshi Iwane; Toshio Yanagida
Myosin-V makes two brownian 90 degrees rotations per 36-nm step.
Nature structural & molecular biology 2007;14(10):968-73.
2007: Yoshikazu Tsukasaki; Kazuo Kitamura; Kazuya Shimizu; Atsuko Hikikoshi Iwane; Yoshimi Takai; Toshio Yanagida
Role of multiple bonds between the single cell adhesion molecules, nectin and cadherin, revealed by high sensitive force measurements.
Journal of molecular biology 2007;367(4):996-1006.
2007: Mitsuhiro Sugawa; Yoshiyuki Arai; Atsuko Hikikoshi Iwane; Yoshiharu Ishii; Toshio Yanagida
Single molecule FRET for the study on structural dynamics of biomolecules.
Bio Systems 2007;88(3):243-50.
2007: Takuya Okada; Hiroto Tanaka; Atsuko Hikikoshi Iwane; Kazuo Kitamura; Mitsuo Ikebe; Toshio Yanagida
The diffusive search mechanism of processive myosin class-V motor involves directional steps along actin subunits.
Biochemical and biophysical research communications 2007;354(2):379-84.
2006: Masatoshi Nishikawa; So Nishikawa; Akira Inoue; Atsuko Hikikoshi Iwane; Toshio Yanagida; Mitsuo Ikebe
A unique mechanism for the processive movement of single-headed myosin-IX.
Biochemical and biophysical research communications 2006;343(4):1159-64.
2006: Mitsuhiro Iwaki; Hiroto Tanaka; Atsuko Hikikoshi Iwane; Eisaku Katayama; Mitsuo Ikebe; Toshio Yanagida
Cargo-binding makes a wild-type single-headed myosin-VI move processively.
Biophysical journal 2006;90(10):3643-52.
2006: Yoshiyuki Arai; Atsuko Hikikoshi Iwane; Tetsuichi Wazawa; Hiroaki Yokota; Yoshiharu Ishii; Tohru Kataoka; Toshio Yanagida
Dynamic polymorphism of Ras observed by single molecule FRET is the basis for molecular recognition.
Biochemical and biophysical research communications 2006;343(3):809-15.
2006: Tetsuichi Wazawa; Yoshiko Ishizuka-Katsura; So Nishikawa; Atsuko Hikikoshi Iwane; Shigeru Aoyama
Grafting of poly(ethylene glycol) onto poly(acrylic acid)-coated glass for a protein-resistant surface.
Analytical chemistry 2006;78(8):2549-56.
2004: Tomonobu M Watanabe; Hiroto Tanaka; Atsuko Hikikoshi Iwane; Saori Maki-Yonekura; Kazuaki Homma; Akira Inoue; Reiko Ikebe; Toshio Yanagida; Mitsuo Ikebe
A one-headed class V myosin molecule develops multiple large (approximately 32-nm) steps successively.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9630-5.
2004: M Yusuf Ali; Kazuaki Homma; Atsuko Hikikoshi Iwane; Kengo Adachi; Hiroyasu Itoh; Kazuhiko Kinosita; Toshio Yanagida; Mitsuo Ikebe
Unconstrained steps of myosin VI appear longest among known molecular motors.
Biophysical journal 2004;86(6):3804-10.
2003: Kayo Hibino; Tomonobu M Watanabe; Jun Kozuka; Atsuko Hikikoshi Iwane; Tomoyo Okada; Tohru Kataoka; Toshio Yanagida; Yasushi Sako
Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells.
Chemphyschem : a European journal of chemical physics and physical chemistry 2003;4(7):748-53.
2003: Mitsuo Ikebe; Akira Inoue; So Nishikawa; Kazuaki Homma; Hiroto Tanaka; Atsuko Hikikoshi Iwane; Eisaku Katayama; Reiko Ikebe; Toshio Yanagida
Motor function of unconventional myosin.
Advances in experimental medicine and biology 2003;538():143-56; discussion 157.
2002: Atsuko Hikikoshi Iwane; Yasunori Komori; Mitsuhiro Iwaki; Toshio Yanagida
[Approach to engineering principle of adaptive biological systems by uncovering unique operation of bio-molecular machines].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(9):1157-64.
2002: Hiroto Tanaka; Kazuaki Homma; Atsuko Hikikoshi Iwane; Eisaku Katayama; Reiko Ikebe; Junya Saito; Toshio Yanagida; Mitsuo Ikebe
The motor domain determines the large step of myosin-V.
Nature 2002;415(6868):192-5.
2000: Toshio Yanagida; Atsuko Hikikoshi Iwane
A large step for myosin.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9357-9.
1999: S Iwatani; Atsuko Hikikoshi Iwane; H Higuchi; Yoshiharu Ishii; Toshio Yanagida
Mechanical and chemical properties of cysteine-modified kinesin molecules.
Biochemistry 1999;38(32):10318-23.
1997: Yoshihisa Inoue; Yoko Y Toyoshima; Atsuko Hikikoshi Iwane; S Morimoto; H Higuchi; Toshio Yanagida
Movements of truncated kinesin fragments with a short or an artificial flexible neck.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7275-80.
1997: Atsuko Hikikoshi Iwane; T Funatsu; Y Harada; M Tokunaga; O Ohara; S Morimoto; Toshio Yanagida
Single molecular assay of individual ATP turnover by a myosin-GFP fusion protein expressed in vitro.
FEBS letters 1997;407(2):235-8.
1997: Atsuko Hikikoshi Iwane; Kazuo Kitamura; M Tokunaga; Toshio Yanagida
Myosin subfragment-1 is fully equipped with factors essential for motor function.
Biochemical and biophysical research communications 1997;230(1):76-80.