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Shuji Izumo

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Japan

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TOP 3
Junhui Yuan; Akiko Yoshimura; Akihiro Hashiguchi; Yujiro Higuchi; Shuji Izumo; Eiji Matsuura; Tomonori Nakamura; Satoshi Nozuma; Yusuke Sakiyama; Hiroshi Takashima
Hereditary sensory and autonomic neuropathy type IID caused by an SCN9A mutation.
Takashi Kawabata; Ikkou Higashimoto; Shuji Izumo; Hiroshi Takashima; Ryuji Kubota
Human T-lymphotropic virus type I (HTLV-I)-specific CD8+ cells accumulate in the lungs of patients infected with HTLV-I with pulmonary involvement.
Kazuhisa Hasui; Shuji Izumo; Yuetsu Tanaka; Jia Wang; Yoshito Eizuru; Takami Matsuyama
Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma.

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2013: Junhui Yuan; Akiko Yoshimura; Akihiro Hashiguchi; Yujiro Higuchi; Shuji Izumo; Eiji Matsuura; Tomonori Nakamura; Satoshi Nozuma; Yusuke Sakiyama; Hiroshi Takashima
Hereditary sensory and autonomic neuropathy type IID caused by an SCN9A mutation.
Neurology 2013;80(18):1641-9.
2012: Takashi Kawabata; Ikkou Higashimoto; Shuji Izumo; Hiroshi Takashima; Ryuji Kubota
Human T-lymphotropic virus type I (HTLV-I)-specific CD8+ cells accumulate in the lungs of patients infected with HTLV-I with pulmonary involvement.
Journal of medical virology 2012;84(7):1120-7.
2012: Kazuhisa Hasui; Shuji Izumo; Yuetsu Tanaka; Jia Wang; Yoshito Eizuru; Takami Matsuyama
Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma.
Acta histochemica et cytochemica 2012;45(2):83-106.
2011: Tomohiro Kozako; Ryuji Kubota; Kakushi Matsushita; Hiroshi Shimeno; Shinji Soeda; Yohann White; Makoto Yoshimitsu; Masaki Akimoto; Shuji Izumo; Naomichi Arima
Programmed death-1 (PD-1)/PD-1 ligand pathway-mediated immune responses against human T-lymphotropic virus type 1 (HTLV-1) in HTLV-1-associated myelopathy/tropical spastic paraparesis and carriers with autoimmune disorders.
Human immunology 2011;72(11):1001-6.
2011: Nashwa H Abdelbary; Hazem M Abdullah; Toshio Matsuzaki; Daisuke Hayashi; Yuetsu Tanaka; Hiroshi Takashima; Shuji Izumo; Ryuji Kubota
Reduced Tim-3 expression on human T-lymphotropic virus type I (HTLV-I) Tax-specific cytotoxic T lymphocytes in HTLV-I infection.
The Journal of infectious diseases 2011;203(7):948-59.
2009: Hui Qin Xing; Hitoshi Hayakawa; Kimiko Izumo; Ryuji Kubota; Ellen Gelpi; Herbert Budka; Shuji Izumo
In vivo expression of proinflammatory cytokines in HIV encephalitis: an analysis of 11 autopsy cases.
Neuropathology : official journal of the Japanese Society of Neuropathology 2009;29(4):433-42.
2009: Moe Moe Aye; Takefumi Kasai; Yukie Tashiro; Hui Qin Xing; Hiroshi Shirahama; Minoru Mitsuda; Takayuki Suetsugu; Keiko Tanaka; Mitsuhiro Osame; Shuji Izumo
CD8 positive T-cell infiltration in the dentate nucleus of paraneoplastic cerebellar degeneration.
Journal of neuroimmunology 2009;208(1-2):136-40.
2009: Hui Qin Xing; Hitoshi Hayakawa; Ellen Gelpi; Ryuji Kubota; Herbert Budka; Shuji Izumo
Reduced expression of excitatory amino acid transporter 2 and diffuse microglial activation in the cerebral cortex in AIDS cases with or without HIV encephalitis.
Journal of neuropathology and experimental neurology 2009;68(2):199-209.
2009: Hui Qin Xing; Takashi Moritoyo; Kazuyasu Mori; Chie Sugimoto; Fumiko Ono; Shuji Izumo
Expression of proinflammatory cytokines and its relationship with virus infection in the brain of macaques inoculated with macrophage-tropic simian immunodeficiency virus.
Neuropathology : official journal of the Japanese Society of Neuropathology 2009;29(1):13-9.
2008: Daisuke Hayashi; Ryuji Kubota; Norihiro Takenouchi; Tomonori Nakamura; Fujio Umehara; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame
Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy.
Journal of neurovirology 2008;14(5):459-63.
2008: Amir Sabouri; Koichiro Usuku; Daisuke Hayashi; Shuji Izumo; Yoshiro Ohara; Mitsuhiro Osame; Mineki Saito
Impaired function of human T-lymphotropic virus type 1 (HTLV-1)-specific CD8+ T cells in HTLV-1-associated neurologic disease.
Blood 2008;112(6):2411-20.
2008: Daisuke Hayashi; Ryuji Kubota; Norihiro Takenouchi; Yuetsu Tanaka; Ryuki Hirano; Hiroshi Takashima; Mitsuhiro Osame; Shuji Izumo; Kimiyoshi Arimura
Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy.
Journal of neuroimmunology 2008;200(1-2):115-24.
2008: Hui Qin Xing; Kazuyasu Mori; Chie Sugimoto; Fumiko Ono; Kimiko Izumo; Ryuji Kuboda; Shuji Izumo
Impaired astrocytes and diffuse activation of microglia in the cerebral cortex in simian immunodeficiency virus-infected Macaques without simian immunodeficiency virus encephalitis.
Journal of neuropathology and experimental neurology 2008;67(6):600-11.
2008: Motohiro Yukitake; Eisaburo Sueoka; Naoko Sueoka-Aragane; Akemi Sato; Hiromi Ohashi; Yusuke Yakushiji; Mineki Saito; Mitsuhiro Osame; Shuji Izumo; Yasuo Kuroda
Significantly increased antibody response to heterogeneous nuclear ribonucleoproteins in cerebrospinal fluid of multiple sclerosis patients but not in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
Journal of neurovirology 2008;14(2):130-5.
2008: Mineki Saito; Koichiro Usuku; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame; Yoshiro Ohara
Increased frequency of CD4+T cells expressing fractalkine receptor CX3CR1 in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), but its AIDS susceptible polymorphisms are not associated with the disease.
Journal of the neurological sciences 2008;266(1-2):13-9.
2008: Eiji Matsuura; Fujio Umehara; Hirohisa Nose; Itsuro Higuchi; E Matsuoka; Koutarou Izumi; Ryuji Kubota; Mineki Saito; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.
Journal of neuropathology and experimental neurology 2008;67(1):41-9.
2007: Hirohisa Nose; Ryuji Kubota; Nilufer P Seth; Peter K C Goon; Yuetsu Tanaka; Shuji Izumo; Koichiro Usuku; Yoshiro Ohara; Kai W Wucherpfennig; Charles R M Bangham; Mitsuhiro Osame; Mineki Saito
Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide.
The Journal of infectious diseases 2007;196(12):1761-72.
2007: Ryuki Hirano; Heidrun Interthal; Cheng Huang; Tomonori Nakamura; Kimiko Deguchi; Kunho Choi; Meenakshi B Bhattacharjee; Kimiyoshi Arimura; Fujio Umehara; Shuji Izumo; Jennifer Northrop; Mustafa A Salih; Ken Inoue; Dawna L Armstrong; James J Champoux; Hiroshi Takashima; Cornelius F Boerkoel
Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
The EMBO journal 2007;26(22):4732-43.
2007: Kimiyoshi Arimura; Masanori Nakagawa; Shuji Izumo; Koichiro Usuku; Yasuto Itoyama; Jun-Ichi Kira; Mitsuhiro Osame
Safety and efficacy of interferon-alpha in 167 patients with human T-cell lymphotropic virus type 1-associated myelopathy.
Journal of neurovirology 2007;13(4):364-72.
2007: Ryuji Kubota; Kousuke Hanada; Yoshitaka Furukawa; Kimiyoshi Arimura; Mitsuhiro Osame; Takashi Gojobori; Shuji Izumo
Genetic stability of human T lymphotropic virus type I despite antiviral pressures by CTLs.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5966-72.
2007: Yutaka Kurano; Masayuki Nakamura; Mio Ichiba; Mieko Matsuda; Emiko Mizuno; Maiko Kato; Asumi Agemura; Shuji Izumo; Akira Sano
In vivo distribution and localization of chorein.
Biochemical and biophysical research communications 2007;353(2):431-5.
2006: Yutaka Kurano; Masayuki Nakamura; Mio Ichiba; Mieko Matsuda; Emiko Mizuno; Maiko Kato; Shuji Izumo; Akira Sano
Chorein deficiency leads to upregulation of gephyrin and GABA(A) receptor.
Biochemical and biophysical research communications 2006;351(2):438-42.
2006: Mineki Saito; Hirohisa Nose; Koichiro Usuku; Amir Sabouri; Toshio Matsuzaki; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Flow cytometry evaluation of the T-cell receptor Vbeta repertoire among human T-cell lymphotropic virus type-1 (HTLV-1) infected individuals: effect of interferon alpha therapy in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Journal of the neurological sciences 2006;246(1-2):37-43.
2006: Shuji Izumo; Ryuji Kubota; Hui Qin Xing
[Retrovirus infection and neurological disorders].
Nō to shinkei = Brain and nerve 2006;58(7):595-604.
2006: Yuji Okamoto; Hiroshi Takashima; Itsuro Higuchi; Wataru Matsuyama; Masahito Suehara; Yasushi Nishihira; Akihiro Hashiguchi; Ryuki Hirano; Arlene R Ng; Masanori Nakagawa; Shuji Izumo; Mitsuhiro Osame; Kimiyoshi Arimura
Molecular mechanism of rigid spine with muscular dystrophy type 1 caused by novel mutations of selenoprotein N gene.
Neurogenetics 2006;7(3):175-83.
2006: Hirohisa Nose; Mineki Saito; Koichiro Usuku; Amir Sabouri; Toshio Matsuzaki; Ryuji Kubota; Nobutaka Eiraku; Yoshitaka Furukawa; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: application of best-fit logistic regression equation based on host genotype, age, and provirus load.
Journal of neurovirology 2006;12(3):171-7.
2006: Yoshitaka Furukawa; Mitsutoshi Tara; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
HTLV-I viral escape and host genetic changes in the development of adult T cell leukemia.
International journal of cancer. Journal international du cancer 2006;118(2):381-7.
2006: Yasuyuki Nobuhara; Koichiro Usuku; Mineki Saito; Shuji Izumo; Kimiyoshi Arimura; Charles R M Bangham; Mitsuhiro Osame
Genetic variability in the extracellular matrix protein as a determinant of risk for developing HTLV-I-associated neurological disease.
Immunogenetics 2006;57(12):944-52.
2005: Shuji Izumo
[Retrovirus infection and neurological disorders].
Rinshō shinkeigaku = Clinical neurology 2005;45(11):815-7.
2005: Toshio Matsuzaki; Mineki Saito; Koichiro Usuku; Hirohisa Nose; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis.
Journal of the neurological sciences 2005;237(1-2):75-81.
2005: Mineki Saito; Nobutaka Eiraku; Koichiro Usuku; Yasuyuki Nobuhara; Wataru Matsumoto; Daisuke Kodama; Amir Sabouri; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
ApaI polymorphism of vitamin D receptor gene is associated with susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in HTLV-1 infected individuals.
Journal of the neurological sciences 2005;232(1-2):29-35.
2005: Amir Sabouri; Mineki Saito; Koichiro Usuku; Sepideh Naghibzadeh Bajestan; Mahmoud Mahmoudi; Mohsen Forughipour; Zahra Sabouri; Zahra Abbaspour; Mohammad E Goharjoo; Esmaeil Khayami; Ali Hasani; Shuji Izumo; Kimiyoshi Arimura; Reza Farid; Mitsuhiro Osame
Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals.
The Journal of general virology 2005;86(Pt 3):773-81.
2004: Daisuke Kodama; Mineki Saito; Wataru Matsumoto; Amir Sabouri; Shuji Izumo; Kimiyoshi Arimura; Koichiro Usuku; Charles R M Bangham; Mitsuhiro Osame
Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional activity influences the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Journal of neuroimmunology 2004;156(1-2):188-94.
2004: Yoshitaka Furukawa; Koichiro Usuku; Shuji Izumo; Mitsuhiro Osame
Human T cell lymphotropic virus type I (HTLV-I) p12I is dispensable for HTLV-I transmission and maintenance of infection in vivo.
AIDS research and human retroviruses 2004;20(10):1092-9.
2004: Amir Sabouri; Mineki Saito; Alun L Lloyd; Alison Levoguer; Aviva W Witkover; Yoshitaka Furukawa; Shuji Izumo; Kimiyoshi Arimura; Sara E Marshall; Koichiro Usuku; Charles R M Bangham; Mitsuhiro Osame
Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
The Journal of infectious diseases 2004;190(7):1279-85.
2004: Mineki Saito; Koichiro Usuku; Yasuyuki Nobuhara; Wataru Matsumoto; Daisuke Kodama; Amir Sabouri; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Serum concentration and genetic polymorphism in the 5'-untraslated region of VEGF is not associated with susceptibility to HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I infected individuals.
Journal of the neurological sciences 2004;219(1-2):157-61.
2004: Harutoshi Sakakima; Yoshihiro Yoshida; Takashi Muramatsu; Kazunori Yone; Masamichi Goto; Kosei Ijiri; Shuji Izumo
Traumatic injury-induced midkine expression in the adult rat spinal cord during the early stage.
Journal of neurotrauma 2004;21(4):471-7.
2004: Shuji Izumo
[HIV infection, acquired immunodeficiency syndrome (AIDS)].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl():219-23.
2004: Mineki Saito; Masanori Nakagawa; Shun Kaseda; Toshio Matsuzaki; Manabu Jonosono; Nobutaka Eiraku; Ryuji Kubota; Norihiro Takenouchi; Masahiro Nagai; Yoshitaka Furukawa; Koichiro Usuku; Shuji Izumo; Mitsuhiro Osame
Decreased human T lymphotropic virus type I (HTLV-I) provirus load and alteration in T cell phenotype after interferon-alpha therapy for HTLV-I-associated myelopathy/tropical spastic paraparesis.
The Journal of infectious diseases 2004;189(1):29-40.
2003: Takayo Arisato; Ryuichi Okubo; Hitoshi Arata; Koji Abe; Kei Fukada; Saburo Sakoda; Akira Shimizu; Xing Hui Qin; Shuji Izumo; Mitsuhiro Osame; Masanori Nakagawa
Clinical and pathological studies of familial amyotrophic lateral sclerosis (FALS) with SOD1 H46R mutation in large Japanese families.
Acta neuropathologica 2003;106(6):561-8.
2003: Amir Sabouri; Mineki Saito; Wataru Matsumoto; Daisuke Kodama; Reza Farid; Shuji Izumo; Koichiro Usuku; Mitsuhiro Osame
A C77G point mutation in CD45 exon 4, which is associated with the development of multiple sclerosis and increased susceptibility to HIV-1 infection, is undetectable in Japanese population.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2003;10(6):737-9.
2003: Kazuhisa Hasui; Tomio Takatsuka; Ryoichi Sakamoto; Sachie Matsushita; Shinichiro Tsuyama; Shuji Izumo; Fusayoshi Murata
Double autoimmunostaining with glycine treatment.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(9):1169-76.
2003: Hui Qin Xing; Takashi Moritoyo; Kazuyasu Mori; Kei Tadakuma; Chie Sugimoto; Fumiko Ono; Hitoshi Hayakawa; Shuji Izumo
Simian immunodeficiency virus encephalitis in the white matter and degeneration of the cerebral cortex occur independently in simian immunodeficiency virus-infected monkey.
Journal of neurovirology 2003;9(4):508-18.
2003: Ryuji Kubota; Yoshitaka Furukawa; Shuji Izumo; Koichiro Usuku; Mitsuhiro Osame
Degenerate specificity of HTLV-1-specific CD8+ T cells during viral replication in patients with HTLV-1-associated myelopathy (HAM/TSP).
Blood 2003;101(8):3074-81.
2003: Yoshitaka Furukawa; Mineki Saito; Wataru Matsumoto; Koichiro Usuku; Yuetsu Tanaka; Shuji Izumo; Mitsuhiro Osame
Different cytokine production in tax-expressing cells between patients with human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis and asymptomatic HTLV-I carriers.
The Journal of infectious diseases 2003;187(7):1116-25.
2003: Chie Sugimoto; Kei Tadakuma; Isao Otani; Takashi Moritoyo; Hirofumi Akari; Fumiko Ono; Yasuhiro Yoshikawa; Tetsutaro Sata; Shuji Izumo; Kazuyasu Mori
nef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.
Journal of virology 2003;77(7):4169-80.
2003: Yoshitaka Furukawa; Ryuji Kubota; Nobutaka Eiraku; Masanori Nakagawa; Koichiro Usuku; Shuji Izumo; Mitsuhiro Osame
Human T-cell lymphotropic virus type I (HTLV-I)-related clinical and laboratory findings for HTLV-I-infected blood donors.
Journal of acquired immune deficiency syndromes (1999) 2003;32(3):328-34.
2003: Norihiro Takenouchi; Yoshihisa Yamano; Koichiro Usuku; Mitsuhiro Osame; Shuji Izumo
Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
Journal of neurovirology 2003;9(1):29-35.
2003: T Kiwaki; Fujio Umehara; Yumiko Arimura; Shuji Izumo; Kimiyoshi Arimura; K Itoh; Mitsuhiro Osame
The clinical and pathological features of peripheral neuropathy accompanied with HTLV-I associated myelopathy.
Journal of the neurological sciences 2003;206(1):17-21.
2002: Shuji Izumo
[HTLV-I-associated myelopathy (HAM)].
Uirusu 2002;52(2):239-44.
2002: Mineki Saito; Itsuro Higuchi; Akiko Saito; Shuji Izumo; Koichiro Usuku; Charles R M Bangham; Mitsuhiro Osame
Molecular analysis of T cell clonotypes in muscle-infiltrating lymphocytes from patients with human T lymphotropic virus type 1 polymyositis.
The Journal of infectious diseases 2002;186(9):1231-41.
2002: Alison Levoguer; Aviva D Witkover; Alun L Lloyd; Katie J M Jeffery; Asna Siddiqui; Sara E Marshall; Mike Bunce; Nobutaka Eiraku; Shuji Izumo; Koichiro Usuku; Mitsuhiro Osame; Charles R M Bangham
Polygenic control of human T lymphotropic virus type I (HTLV-I) provirus load and the risk of HTLV-I-associated myelopathy/tropical spastic paraparesis.
The Journal of infectious diseases 2002;186(7):932-9.
2002: Demidmaa Tuvdendorj; Yasushi Isashiki; Norio Ohba; Shunro Sonoda; Shuji Izumo
Two Japanese patients with mutations in the XLRS1 gene.
Retina (Philadelphia, Pa.) 2002;22(3):354-7.
2002: xin wang; Hiroshi Miyake; Mika Okamoto; Mineki Saito; Jun-ichi Fujisawa; Yuetsu Tanaka; Shuji Izumo; Masanori Baba
Inhibition of the tax-dependent human T-lymphotropic virus type I replication in persistently infected cells by the fluoroquinolone derivative k-37.
Molecular pharmacology 2002;61(6):1359-65.
2002: Kazuhisa Hasui; Tomio Takatsuka; Ryoichi Sakamoto; Liying Su; Sachie Matsushita; Shinichiro Tsuyama; Shuji Izumo; Fusayoshi Murata
Improvement of supersensitive immunohistochemistry with an autostainer: a simplified catalysed signal amplification system.
The Histochemical journal 2002;34(5):215-22.
2002: xin wang; Mika Okamoto; M Kawamura; Shuji Izumo; Masanori Baba
Inhibition of human T-lymphotropic virus type I gene expression by the Streptomyces-derived substance EM2487.
Antiviral chemistry & chemotherapy 2002;13(3):177-83.
2002: Oscar Marin; Kazuhisa Hasui; Carlos Remondegui; Eiichi Sato; Moe Moe Aye; Norihiro Takenouchi; Shuji Izumo; Kazuo Tajima
Adult T-cell leukemia/lymphoma in Jujuy, north-west Argentina.
Pathology international 2002;52(5-6):348-57.
2002: Fujio Umehara; Kayoko Itoh; Kumiko Michizono; Mayumi Abe; Shuji Izumo; Mitsuhiro Osame
Involvement of Fas/Fas ligand system in the spinal cords of HTLV-I-associated myelopathy.
Acta neuropathologica 2002;103(4):384-90.
2002: Yoshihisa Yamano; Masahiro Nagai; Meghan Brennan; Carlos A Mora; Samantha S Soldan; Utano Tomaru; Norihiro Takenouchi; Shuji Izumo; Mitsuhiro Osame; Steven Jacobson
Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP).
Blood 2002;99(1):88-94.
2001: Takao Setoguchi; Kazunori Yone; E Matsuoka; H Takenouchi; K Nakashima; Takashi Sakou; Setsuro Komiya; Shuji Izumo
Traumatic injury-induced BMP7 expression in the adult rat spinal cord.
Brain research 2001;921(1-2):219-25.
2001: Masahiko Makino; Atae Utsunomiya; Yumi Maeda; Satoshi Shimokubo; Shuji Izumo; Masanori Baba
Association of CD40 ligand expression on HTLV-I-infected T cells and maturation of dendritic cells.
Scandinavian journal of immunology 2001;54(6):574-81.
2001: Toshio Matsuzaki; Masanori Nakagawa; Masahiro Nagai; Koichiro Usuku; Itsuro Higuchi; Kimiyoshi Arimura; H Kubota; Shuji Izumo; suminori akiba; Mitsuhiro Osame
HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years.
Journal of neurovirology 2001;7(3):228-34.
2001: Yoshitaka Furukawa; Ryuji Kubota; Mitsutoshi Tara; Shuji Izumo; Mitsuhiro Osame
Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia.
Blood 2001;97(4):987-93.
2000: Katie J M Jeffery; A A Siddiqui; Mike Bunce; Alun L Lloyd; Alison Levoguer; Aviva D Witkover; Shuji Izumo; Koichiro Usuku; Kenneth I Welsh; Mitsuhiro Osame; Charles R M Bangham
The influence of HLA class I alleles and heterozygosity on the outcome of human T cell lymphotropic virus type I infection.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7278-84.
2000: Toshio Matsuzaki; Masanori Nakagawa; Masahiro Nagai; Yasuyuki Nobuhara; Koichiro Usuku; Itsuro Higuchi; K Takahashi; Takashi Moritoyo; Kimiyoshi Arimura; Shuji Izumo; suminori akiba; Mitsuhiro Osame
HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with amyotrophic lateral sclerosis-like manifestations.
Journal of neurovirology 2000;6(6):544-8.
2000: Yoshitaka Furukawa; M Yamashita; Koichiro Usuku; Shuji Izumo; Masanori Nakagawa; Mitsuhiro Osame
Phylogenetic subgroups of human T cell lymphotropic virus (HTLV) type I in the tax gene and their association with different risks for HTLV-I-associated myelopathy/tropical spastic paraparesis.
The Journal of infectious diseases 2000;182(5):1343-9.
2000: Shuji Izumo; Fujio Umehara; Mitsuhiro Osame
HTLV-I-associated myelopathy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S65-8.
2000: M M Aye; E Matsuoka; Takashi Moritoyo; Fujio Umehara; Masahito Suehara; Y Hokezu; H Yamanaka; Yasushi Isashiki; Mitsuhiro Osame; Shuji Izumo
Histopathological analysis of four autopsy cases of HTLV-I-associated myelopathy/tropical spastic paraparesis: inflammatory changes occur simultaneously in the entire central nervous system.
Acta neuropathologica 2000;100(3):245-52.
2000: Fujio Umehara; Mayumi Abe; Yoshimizu Koreeda; Shuji Izumo; Mitsuhiro Osame
Axonal damage revealed by accumulation of beta-amyloid precursor protein in HTLV-I-associated myelopathy.
Journal of the neurological sciences 2000;176(2):95-101.
2000: E Matsuoka; Koichiro Usuku; Manabu Jonosono; Norihiro Takenouchi; Shuji Izumo; Mitsuhiro Osame
CD44 splice variant involvement in the chronic inflammatory disease of the spinal cord: HAM/TSP.
Journal of neuroimmunology 2000;102(1):1-7.
1999: Norihiro Takenouchi; E Matsuoka; Takashi Moritoyo; Masahiro Nagai; K Katsuta; Kazuhisa Hasui; K Ueno; Yoshito Eizuru; Koichiro Usuku; Mitsuhiro Osame; Yasushi Isashiki; Shuji Izumo
Molecular pathologic analysis of the tonsil in HTLV-I-infected individuals.
Journal of acquired immune deficiency syndromes (1999) 1999;22(2):200-7.
1999: Masanori Nakagawa; Hiroshi Takashima; Masahito Suehara; Mineki Saito; Akiko Saito; N Kanzato; Toshio Matsuzaki; K Hirata; Shuji Izumo; Joseph D Terwilliger; Mitsuhiro Osame
Hereditary motor and sensory neuropathy with proximal dominant involvement: clinical, pathological, and genetic features.
Annals of the New York Academy of Sciences 1999;883():449-52.
1999: Mineki Saito; N Nakamura; Masahiro Nagai; K Shirakawa; H Sato; N Kawahigashi; Yoshitaka Furukawa; Koichiro Usuku; Masanori Nakagawa; Shuji Izumo; Mitsuhiro Osame
Increased levels of soluble Fas ligand in CSF of rapidly progressive HTLV-1-associated myelopathy/tropical spastic paraparesis patients.
Journal of neuroimmunology 1999;98(2):221-6.
1999: Masaru Inose; Itsuro Higuchi; Kowa Yoshimine; Kimiyoshi Arimura; Mitsuhiro Osame; Shuji Izumo; Y Hokezu
[A study of clinical symptoms, muscle pathology, therapeutic response, and prognosis of myositis in patients with HTLV-1 associated myelopathy (HAM)].
Rinshō shinkeigaku = Clinical neurology 1999;39(8):807-11.
1999: Takashi Moritoyo; Shuji Izumo; Hiroyoko Moritoyo; Yuetsu Tanaka; Y Kiyomatsu; Masahiro Nagai; Koichiro Usuku; Masaru Sorimachi; Mitsuhiro Osame
Detection of human T-lymphotropic virus type I p40tax protein in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
Journal of neurovirology 1999;5(3):241-8.
1999: Hiroshi Takashima; Masanori Nakagawa; Akio Kanzaki; Yoshihito Yawata; Takashi Horikiri; Toshio Matsuzaki; Masahito Suehara; Shuji Izumo; Mitsuhiro Osame
Germline mosaicism of MPZ gene in Dejerine-Sottas syndrome (HMSN III) associated with hereditary stomatocytosis.
Neuromuscular disorders : NMD 1999;9(4):232-8.
1999: Masahiko Makino; Satoshi Shimokubo; Shinichi Wakamatsu; Shuji Izumo; Masanori Baba
The role of human T-lymphotropic virus type 1 (HTLV-1)-infected dendritic cells in the development of HTLV-1-associated myelopathy/tropical spastic paraparesis.
Journal of virology 1999;73(6):4575-81.
1999: Mayumi Abe; Fujio Umehara; Ryuji Kubota; Takashi Moritoyo; Shuji Izumo; Mitsuhiro Osame
Activation of macrophages/microglia with the calcium-binding proteins MRP14 and MRP8 is related to the lesional activities in the spinal cord of HTLV-I associated myelopathy.
Journal of neurology 1999;246(5):358-64.
1999: Masahiko Makino; M Azuma; Shinichi Wakamatsu; Yukio Suruga; Shuji Izumo; MM Yokoyama; Masanori Baba
Marked suppression of T cells by a benzothiophene derivative in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
Clinical and diagnostic laboratory immunology 1999;6(3):316-22.
1999: Masanori Nakagawa; Masahito Suehara; Akiko Saito; Hiroshi Takashima; Fujio Umehara; Mineki Saito; N Kanzato; Toshio Matsuzaki; S Takenaga; S Sakoda; Shuji Izumo; Mitsuhiro Osame
A novel MPZ gene mutation in dominantly inherited neuropathy with focally folded myelin sheaths.
Neurology 1999;52(6):1271-5.
1999: Katie J M Jeffery; Koichiro Usuku; SE Hall; Wataru Matsumoto; Graham P Taylor; J Procter; Mike Bunce; G S Ogg; Kenneth I Welsh; Jonathan N Weber; Alun L Lloyd; Martin A Nowak; Masahiro Nagai; Daisuke Kodama; Shuji Izumo; Mitsuhiro Osame; Charles R M Bangham
HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3848-53.
1999: T Kasai; Hitoshi Ikeda; Utano Tomaru; I Yamashita; Osamu Ohya; K Morita; A Wakisaka; E Matsuoka; Takashi Moritoyo; K Hashimoto; Itsuro Higuchi; Shuji Izumo; Mitsuhiro Osame; Takashi Yoshiki
A rat model of human T lymphocyte virus type I (HTLV-I) infection: in situ detection of HTLV-I provirus DNA in microglia/macrophages in affected spinal cords of rats with HTLV-I-induced chronic progressive myeloneuropathy.
Acta neuropathologica 1999;97(2):107-12.
1998: Masahiro Nagai; Koichiro Usuku; Wataru Matsumoto; Daisuke Kodama; Norihiro Takenouchi; Takashi Moritoyo; S Hashiguchi; M Ichinose; Charles R M Bangham; Shuji Izumo; Mitsuhiro Osame
Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP.
Journal of neurovirology 1998;4(6):586-93.
1998: M M Aye; Shuji Izumo; S Inada; Yasushi Isashiki; H Yamanaka; K Matsumuro; Y Kawasaki; Y Sawashima; J Fujiyama; Kimiyoshi Arimura; Mitsuhiro Osame
Histopathological and ultrastructural features of feline hereditary cerebellar cortical atrophy: a novel animal model of human spinocerebellar degeneration.
Acta neuropathologica 1998;96(4):379-87.
1998: E Matsuoka; Norihiro Takenouchi; K Hashimoto; N Kashio; Takashi Moritoyo; Itsuro Higuchi; Yasushi Isashiki; Eiichi Sato; Mitsuhiro Osame; Shuji Izumo
Perivascular T cells are infected with HTLV-I in the spinal cord lesions with HTLV-I-associated myelopathy/tropical spastic paraparesis: double staining of immunohistochemistry and polymerase chain reaction in situ hybridization.
Acta neuropathologica 1998;96(4):340-6.
1998: Fujio Umehara; Y Okada; N Fujimoto; Mayumi Abe; Shuji Izumo; Mitsuhiro Osame
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in HTLV-I-associated myelopathy.
Journal of neuropathology and experimental neurology 1998;57(9):839-49.
1998: K Hashimoto; Itsuro Higuchi; Mitsuhiro Osame; Shuji Izumo
Quantitative in situ PCR assay of HTLV-1 infected cells in peripheral blood lymphocytes of patients with ATL, HAM/TSP and asymptomatic carriers.
Journal of the neurological sciences 1998;159(1):67-72.
1998: S Wang; Yoshihiro Yoshida; M Goto; Takashi Moritoyo; J Tsutsui; Shuji Izumo; E Sato; Takashi Muramatsu; M Osame
Midkine exists in astrocytes in the early stage of cerebral infarction.
Brain research. Developmental brain research 1998;106(1-2):205-9.
1998: Bernd Kitze; Koichiro Usuku; Yoshihisa Yamano; Shinji Yashiki; Motoyuki Nakamura; Toshinobu Fujiyoshi; Shuji Izumo; Mitsuhiro Osame; Shunro Sonoda
Human CD4+ T lymphocytes recognize a highly conserved epitope of human T lymphotropic virus type 1 (HTLV-1) env gp21 restricted by HLA DRB1*0101.
Clinical and experimental immunology 1998;111(2):278-85.
1997: Anat Achiron; Itsuro Higuchi; Norihiro Takenouchi; E Matsuoka; K Hashimoto; Shuji Izumo; Batya Shohat; Mitsuhiro Osame
Detection of HTLV type I provirus by in situ polymerase chain reaction in mouthwash mononuclear cells of HAM/TSP patients and HTLV type I carriers.
AIDS research and human retroviruses 1997;13(12):1067-70.
1997: Hiroshi Takashima; Masanori Nakagawa; K Nakahara; Masahito Suehara; Toshio Matsuzaki; Itsuro Higuchi; H Higa; Kimiyoshi Arimura; T Iwamasa; Shuji Izumo; Mitsuhiro Osame
A new type of hereditary motor and sensory neuropathy linked to chromosome 3.
Annals of neurology 1997;41(6):771-80.
1997: Yoshihisa Yamano; Bernd Kitze; Shinji Yashiki; Koichiro Usuku; Toshinobu Fujiyoshi; T Kaminagayoshi; Kazuhiko Unoki; Shuji Izumo; Mitsuhiro Osame; Shunro Sonoda
Preferential recognition of synthetic peptides from HTLV-I gp21 envelope protein by HLA-DRB1 alleles associated with HAM/TSP (HTLV-I-associated myelopathy/tropical spastic paraparesis).
Journal of neuroimmunology 1997;76(1-2):50-60.
1997: Mitsuhiro Osame; Masanori Nakagawa; Fujio Umehara; Shinji Ijichi; Takashi Moritoyo; Itsuro Higuchi; Koichiro Usuku; Kimiyoshi Arimura; Shuji Izumo
Recent studies on the epidemiology, clinical features and pathogenic mechanisms of HTLV-I associated myelopathy (HAM/TSP) and other diseases associated to HTLV.
Journal of neurovirology 1997;3 Suppl 1():S50-1.
1997: Shuji Izumo; Fujio Umehara; N Kashio; Ryuji Kubota; Eiichi Sato; Mitsuhiro Osame
Neuropathology of HTLV-1-associated myelopathy (HAM/TSP).
Leukemia 1997;11 Suppl 3():82-4.
1996: Bernd Kitze; Koichiro Usuku; Shinji Yashiki; Shinji Ijichi; Toshinobu Fujiyoshi; M Nakamura; Shuji Izumo; Mitsuhiro Osame; Shunro Sonoda
Intrathecal humoral immune response in HAM/TSP in relation to HLA haplotype analysis.
Acta neurologica Scandinavica 1996;94(4):287-93.
1996: Masanori Nakagawa; K Nakahara; Y Maruyama; Masaharu Kawabata; Itsuro Higuchi; H Kubota; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.
Journal of neurovirology 1996;2(5):345-55.
1996: Itsuro Higuchi; K Hashimoto; E Matsuoka; R Rosales; Masanori Nakagawa; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame
The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes.
Acta neuropathologica 1996;92(4):358-61.
1996: Takashi Moritoyo; Todd A Reinhart; H Moritoyo; E Sato; Shuji Izumo; Mitsuhiro Osame; Ashley T Haase
Human T-lymphotropic virus type I-associated myelopathy and tax gene expression in CD4+ T lymphocytes.
Annals of neurology 1996;40(1):84-90.
1996: K Ohshima; K Hashimoto; Shuji Izumo; J Suzumiya; M Kikuchi
Detection of human T lymphotrophic virus type I (HTLV-I) DNA and mRNA in individual cells by polymerase chain reaction (PCR) in situ hybridization (ISH) and reverse transcription (RT)-PCR ISH.
Hematological oncology 1996;14(2):91-100.
1996: Bernd Kitze; Koichiro Usuku; Shuji Izumo; M Nakamura; H Shiraki; Shinji Ijichi; Shinji Yashiki; Toshinobu Fujiyoshi; Shunro Sonoda; M Osame
Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy.
Journal of neurology 1996;243(5):393-400.
1996: Masahiro Nagai; Shinji Yashiki; Toshinobu Fujiyoshi; C Fujiyama; Bernd Kitze; Shuji Izumo; Mitsuhiro Osame; Shunro Sonoda
Characterization of a unique T-cell clone established from a patient with HAM/TSP which recognized HTLV-I-infected T-cell antigens as well as spinal cord tissue antigens.
Journal of neuroimmunology 1996;65(2):97-105.
1996: Shuji Izumo; I Goto; Y Itoyama; T Okajima; S Watanabe; Y Kuroda; S Araki; M Mori; S Nagataki; S Matsukura; T Akamine; Masanori Nakagawa; I Yamamoto; Mitsuhiro Osame
Interferon-alpha is effective in HTLV-I-associated myelopathy: a multicenter, randomized, double-blind, controlled trial.
Neurology 1996;46(4):1016-21.
1996: Shuji Izumo; N Kashio; K Hashimoto; Mitsuhiro Osame
[In situ PCR detection of HTLV-1 provirus in spinal cord lesions with HAM/TSP].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(5):656-9.
1996: Fujio Umehara; Shuji Izumo; M Takeya; K Takahashi; Eiichi Sato; Mitsuhiro Osame
Expression of adhesion molecules and monocyte chemoattractant protein -1 (MCP-1) in the spinal cord lesions in HTLV-I-associated myelopathy.
Acta neuropathologica 1996;91(4):343-50.
1996: Shinji Ijichi; Masanori Nakagawa; Fujio Umehara; Itsuro Higuchi; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame
HAM/TSP: recent perspectives in Japan.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;13 Suppl 1():S26-32.
1995: S R Maroushek; Mitsuhiro Osame; Shuji Izumo; Ryuji Kubota; E Sato; C Bartholomew; Ashley T Haase
Sequence analysis of human T cell lymphotropic virus type I (HTLV-I) Env genes amplified from central nervous system tissues of patients with HTLV-I-associated myelopathy or leukemia.
Microbial pathogenesis 1995;19(5):317-33.
1995: Yoshitaka Furukawa; T Okadome; Mitsutoshi Tara; Kiyoshige Niina; Shuji Izumo; Mitsuhiro Osame
Human T-cell lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis with acute type of adult T-cell leukemia.
Internal medicine (Tokyo, Japan) 1995;34(11):1130-3.
1995: Fujio Umehara; T Kiwaki; H Yoshikawa; T Nishimura; Masanori Nakagawa; Wataru Matsumoto; K Hashimoto; Shuji Izumo; Yumiko Arimura; Kimiyoshi Arimura
Deletion in chromosome 17p11.2 including the peripheral myelin protein-22 (PMP-22) gene in hereditary neuropathy with liability to pressure palsies.
Journal of the neurological sciences 1995;133(1-2):173-6.
1995: Shinji Ijichi; Shuji Izumo; Masahiro Nagai; K Shinmyozu; W W Hall; Mitsuhiro Osame
Anti-viral and immunomodulatory effects of interferon-alpha on cultured lymphocytes from patients with human T lymphotropic virus type I-associated myelopathy (HAM/TSP).
Journal of neuroimmunology 1995;61(2):213-21.
1995: Itsuro Higuchi; K Hashimoto; N Kashio; Shuji Izumo; Masaru Inose; K Izumi; R Ohkubo; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Detection of HTLV-I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis.
Muscle & nerve 1995;18(8):854-8.
1995: A Nakamura; K Izumi; Fujio Umehara; M Kuriyama; Youichi Hokezu; Masanori Nakagawa; K Shimmyozu; Shuji Izumo; Mitsuhiro Osame
Familial spastic paraplegia with mental impairment and thin corpus callosum.
Journal of the neurological sciences 1995;131(1):35-42.
1995: Masanori Nakagawa; Shuji Izumo; Shinji Ijichi; H Kubota; Kimiyoshi Arimura; Masaharu Kawabata; Mitsuhiro Osame
HTLV-I-associated myelopathy: analysis of 213 patients based on clinical features and laboratory findings.
Journal of neurovirology 1995;1(1):50-61.
1995: Kimiyoshi Arimura; Yumiko Arimura; H Moritoyo; Y Tokimura; S Takenaga; Yoshito Sonoda; H Yamanaka; Masanori Nakagawa; Shuji Izumo; Mitsuhiro Osame
How helpful is thoracic paraspinal EMG in HAM/TSP?
Muscle & nerve 1995;18(2):248-50.
1995: Itsuro Higuchi; K Hashimoto; N Kashio; Shuji Izumo; H Matsuoka; Masanori Nakagawa; Mitsuhiro Osame
In situ polymerase chain reaction detection of HTLV-I provirus and expression of the p53 tumor suppressor gene in infiltrating cells in skeletal muscle from a patient with adult T cell leukemia.
Acta neuropathologica 1995;90(3):323-7.
1994: K Matsumuro; Shuji Izumo; Fujio Umehara; Mitsuhiro Osame
Chronic inflammatory demyelinating polyneuropathy: histological and immunopathological studies on biopsied sural nerves.
Journal of the neurological sciences 1994;127(2):170-8.
1994: Fujio Umehara; A Nakamura; Shuji Izumo; Ryuji Kubota; Shinji Ijichi; N Kashio; K Hashimoto; Koichiro Usuku; Eiichi Sato; Mitsuhiro Osame
Apoptosis of T lymphocytes in the spinal cord lesions in HTLV-I-associated myelopathy: a possible mechanism to control viral infection in the central nervous system.
Journal of neuropathology and experimental neurology 1994;53(6):617-24.
1994: K Matsumuro; Shuji Izumo; Fujio Umehara; Takayo Arisato; Ikuro Maruyama; Suguru Yonezawa; H Shirahama; Eiichi Sato; Mitsuhiro Osame
Paraneoplastic vasculitic neuropathy: immunohistochemical studies on a biopsied nerve and post-mortem examination.
Journal of internal medicine 1994;236(2):225-30.
1994: Ryuji Kubota; Fujio Umehara; Shuji Izumo; Shinji Ijichi; K Matsumuro; Shinji Yashiki; Toshinobu Fujiyoshi; Shunro Sonoda; Mitsuhiro Osame
HTLV-I proviral DNA amount correlates with infiltrating CD4+ lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy.
Journal of neuroimmunology 1994;53(1):23-9.
1994: Fujio Umehara; Shuji Izumo; A T Ronquillo; K Matsumuro; Eiichi Sato; Mitsuhiro Osame
Cytokine expression in the spinal cord lesions in HTLV-I-associated myelopathy.
Journal of neuropathology and experimental neurology 1994;53(1):72-7.
1993: Shinji Ijichi; Shuji Izumo; Nobutaka Eiraku; K Machigashira; Ryuji Kubota; Masahiro Nagai; N Ikegami; N Kashio; Fujio Umehara; Ikuro Maruyama
An autoaggressive process against bystander tissues in HTLV-I-infected individuals: a possible pathomechanism of HAM/TSP.
Medical hypotheses 1993;41(6):542-7.
1993: Fujio Umehara; Shuji Izumo; Masanori Nakagawa; A T Ronquillo; K Takahashi; K Matsumuro; Eiichi Sato; Mitsuhiro Osame
Immunocytochemical analysis of the cellular infiltrate in the spinal cord lesions in HTLV-I-associated myelopathy.
Journal of neuropathology and experimental neurology 1993;52(4):424-30.
1993: Fujio Umehara; Mayumi Abe; Masanori Nakagawa; Shuji Izumo; Kimiyoshi Arimura; K Matsumuro; Mitsuhiro Osame
Werner's syndrome associated with spastic paraparesis and peripheral neuropathy.
Neurology 1993;43(6):1252-4.
1993: Itsuro Higuchi; E S Montemayor; Shuji Izumo; Masaru Inose; Mitsuhiro Osame
Immunohistochemical characteristics of polymyositis in patients with HTLV-I-associated myelopathy and HTLV-I carriers.
Muscle & nerve 1993;16(5):472-6.
1993: Mayumi Abe; Fujio Umehara; Masanori Nakagawa; Shuji Izumo; Mitsuhiro Osame
[A case of Werner syndrome associated with spastic paraparesis and peripheral neuropathy].
Rinshō shinkeigaku = Clinical neurology 1993;33(4):411-5.
1993: Ryuji Kubota; Toshinobu Fujiyoshi; Shuji Izumo; Shinji Yashiki; Ikuro Maruyama; Mitsuhiro Osame; Shunro Sonoda
Fluctuation of HTLV-I proviral DNA in peripheral blood mononuclear cells of HTLV-I-associated myelopathy.
Journal of neuroimmunology 1993;42(2):147-54.
1993: K Matsumuro; Shuji Izumo; Y Minauchi; Masaru Inose; Itsuro Higuchi; Mitsuhiro Osame
Chronic demyelinating neuropathy and intra-axonal polyglucosan bodies.
Acta neuropathologica 1993;86(1):95-9.
1993: Fujio Umehara; S Takenaga; Masanori Nakagawa; K Takahashi; Shuji Izumo; K Matsumuro; S Sakota; T Nishimura; H Yoshikawa; Mitsuhiro Osame
Dominantly inherited motor and sensory neuropathy with excessive myelin folding complex.
Acta neuropathologica 1993;86(6):602-8.
1993: K Matsumuro; Shuji Izumo; Itsuro Higuchi; A T Ronquillo; K Takahashi; Mitsuhiro Osame
Experimental germanium dioxide-induced neuropathy in rats.
Acta neuropathologica 1993;86(6):547-53.
1992: T Ijichi; Itsuro Higuchi; H Fukunaga; Shuji Izumo; Mitsuhiro Osame
Lymphocyte subsets in muscle biopsies of human T-lymphotropic virus type I carriers with polymyositis.
Internal medicine (Tokyo, Japan) 1992;31(8):973-7.
1992: Masaru Inose; Itsuro Higuchi; Kowa Yoshimine; Masahito Suehara; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Pathological changes in skeletal muscle in HTLV-I-associated myelopathy.
Journal of the neurological sciences 1992;110(1-2):73-8.
1992: Y Mimura; M Johnosono; Shuji Izumo; M Kuriyama; Mitsuhiro Osame
[Adult-onset neuronal ceroid lipofuscinosis--a case report with biological study].
Rinshō shinkeigaku = Clinical neurology 1992;32(7):771-3.
1992: Shuji Izumo; T Ijichi; Itsuro Higuchi; A Tashiro; K Takahashi; Mitsuhiro Osame
Neuropathology of HTLV-I-associated myelopathy--a report of two autopsy cases.
Acta paediatrica Japonica; Overseas edition 1992;34(3):358-64.
1992: Masanori Nakagawa; Shuji Izumo; M Ikurou; Mitsuhiro Osame
[The clinical features of HTLV-I infection. HTLV-I associated myelopathy].
Uirusu 1992;42(1):21-8.
1992: Masahito Suehara; Shuji Izumo; Ichiro Kumamoto; Mitsuhiro Osame
[Significance of anti-HTLV-I antibody in cerebrospinal fluid in diagnosis of HTLV-I associated myelopathy (HAM)].
Rinsho byori. The Japanese journal of clinical pathology 1992;40(3):311-6.
1991: T Ijichi; Shuji Izumo; K Takahashi; A Tashiro; Itsuro Higuchi; Mitsuhiro Osame
Lymphocyte subsets in sural nerves from patients with vasculitic neuropathy.
Muscle & nerve 1991;14(6):574-5.
1991: Fujio Umehara; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Polyneuropathy induced by m-tolyl methyl carbamate intoxication.
Journal of neurology 1991;238(1):47-8.
1991: Itsuro Higuchi; K Takahashi; K Nakahara; Shuji Izumo; Masanori Nakagawa; Mitsuhiro Osame
Experimental germanium myopathy.
Acta neuropathologica 1991;82(1):55-9.
1990: Shinji Ijichi; Kiyoshige Niina; Mitsutoshi Tara; F Nakamura; Naomi Ijichi; Shuji Izumo; Mitsuhiro Osame
Mononeuropathy associated with hyperthyroidism.
Journal of neurology, neurosurgery, and psychiatry 1990;53(12):1109-10.
1990: K Matsumuro; Mitsuhiro Osame; Nobutaka Eiraku; K Machigashira; Shuji Izumo; K Otsuka; S Otani; M Mori; S Harada; K Yanagi
HTLV-I-associated myelopathy, tropical spastic paraparesis, and Borrelia burgdorferi.
Annals of neurology 1990;27(3):337.
1990: Fujio Umehara; Shuji Izumo; M Zyounosono; Mitsuhiro Osame
An autopsied case of the Crow-Fukase syndrome: a neuropathological study with emphasis on spinal roots.
Acta neuropathologica 1990;80(5):563-7.
1989: Shinji Ijichi; Naomi Ijichi; Kiyoshige Niina; M Kuriyama; Shuji Izumo; F Nakamura; Mitsuhiro Osame
Type IIa hyperlipoproteinemia masquerading as cerebrotendinous xanthomatosis.
Journal of the neurological sciences 1989;94(1-3):101-5.
1989: Shinji Ijichi; Nobutaka Eiraku; Mitsuhiro Osame; Shuji Izumo; Ryuji Kubota; Ikuro Maruyama; M Matsumoto; T Niimura; Shunro Sonoda
Activated T lymphocytes in cerebrospinal fluid of patients with HTLV-I-associated myelopathy (HAM/TSP).
Journal of neuroimmunology 1989;25(2-3):251-4.
1989: Y Yoshida; R Hamada; H Kamitsuchibashi; K Yamamoto; Masanori Nakagawa; Shuji Izumo; Itsuro Higuchi; Y Soejima; Mitsuhiro Osame; A Igata
Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis.
Acta neurologica Scandinavica 1989;80(5):444-50.
1989: Shinji Ijichi; Nobutaka Eiraku; Mitsuhiro Osame; Shuji Izumo; Ryuji Kubota; Ikuro Maruyama; M Matsumoto; Shunro Sonoda
In vitro modulation of lymphocyte proliferation by prednisolone and interferon-alpha in patients with HTLV-I-associated myelopathy (HAM).
Journal of neuroimmunology 1989;23(2):175-8.
1989: J C Navarro; R L Rosales; A T Ordinario; Shuji Izumo; Mitsuhiro Osame
Acute dapsone-induced peripheral neuropathy.
Muscle & nerve 1989;12(7):604-6.
1989: I Kitajima; M Kuriyama; F Usuki; Shuji Izumo; Mitsuhiro Osame; T Suganuma; Fusayoshi Murata; Keiji Nagamatsu
Nasu-Hakola disease (membranous lipodystrophy). Clinical, histopathological and biochemical studies of three cases.
Journal of the neurological sciences 1989;91(1-2):35-52.
1989: Itsuro Higuchi; Shuji Izumo; M Kuriyama; Masahito Suehara; Masanori Nakagawa; H Fukunaga; Mitsuhiro Osame; S Ohtsubo; K Miyata
Germanium myopathy: clinical and experimental pathological studies.
Acta neuropathologica 1989;79(3):300-4.
1988: Kimiyoshi Arimura; Y Murai; R L Rosales; Shuji Izumo
Spinal roots of rats poisoned with methylmercury: physiology and pathology.
Muscle & nerve 1988;11(7):762-8.
1988: M Osame; A Igata; M Matsumoto; Shuji Izumo; Koichiro Usuku; R L Rosales; Mitsutoshi Tara
HTLV-1 associated myelopathy (HAM).
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1988;62 Suppl():240-8.
1988: R L Rosales; J Navarro; Shuji Izumo; Mitsuhiro Osame; O Naidas; A Ordinario; A Igata
Sural nerve morphology in asymptomatic uremia.
European neurology 1988;28(3):156-60.
1988: Isao Kitajima; Mitsuhiro Osame; Shuji Izumo; A Igata
Immunological studies of HTLV-I associated myelopathy.
Autoimmunity 1988;1(2):125-31.
1987: R L Rosales; J C Navarro; Shuji Izumo; Mitsuhiro Osame; A Igata; O Naidas; L Nazareno-Rosales
Normal sural nerve morphometry in acute uraemia.
Journal of neurology, neurosurgery, and psychiatry 1987;50(7):942-3.
1987: Mitsuhiro Osame; M Matsumoto; Koichiro Usuku; Shuji Izumo; Naomi Ijichi; H Amitani; Mitsutoshi Tara; A Igata
Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type I and adult T-cell leukemialike cells.
Annals of neurology 1987;21(2):117-22.
1986: Mitsuhiro Osame; Koichiro Usuku; Shuji Izumo; Naomi Ijichi; H Amitani; A Igata; M Matsumoto; Mitsutoshi Tara
HTLV-I associated myelopathy, a new clinical entity.
Lancet 1986;1(8488):1031-2.
1984: Y Yoshida; R Hamada; H Kamitsuchibashi; K Yamamoto; Shuji Izumo; Itsuro Higuchi; A Igata; S Kaneko; Y Sato
[Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1984;73(3):316-22.