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Julie Izzo

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Jennifer Y Pan; Angel Quin; Xifeng Wu; Jaffer A Ajani; Yubo Gong; Jian Gu; Maosheng Hung; Julie G Izzo
Association of Aurora-A (STK15) kinase polymorphisms with clinical outcome of esophageal cancer treated with preoperative chemoradiation.
Yan Wang; Tsung-Teh Wu; Yun Wu; Weiya Xia; Chia-Jui Yen; Jaffer Ajani; Navtej S Buttar; Wei-Chao Chang; Chung-Hsuan Chen; Qingqing Ding; Jennifer L Hsu; Jung-Mao Hsu; Tzu-Hsuan Huang; Longfei Huo; Julie G Izzo; Adam M Labaff; Chien-Chen Lai; Jing-Yu Lang; Dung-Fang Lee; Chia-Wei Li; Dongping Liu; Stephanie A Miller; Fuu-Jen Tsai; Huamin Wang; Kenneth K Wang; Xuemei Wang; Mien-Chie Hung
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Jaffer A Ajani; Xuemei Wang; Julie G Izzo; Christopher H Crane; Cathy Eng; John M Skibber; Prajnan Das; Asif Rashid
Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation.

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All Publications

2012: Jennifer Y Pan; Angel Quin; Xifeng Wu; Jaffer A Ajani; Yubo Gong; Jian Gu; Maosheng Hung; Julie G Izzo
Association of Aurora-A (STK15) kinase polymorphisms with clinical outcome of esophageal cancer treated with preoperative chemoradiation.
Cancer 2012;118(17):4346-53.
2012: Yan Wang; Tsung-Teh Wu; Yun Wu; Weiya Xia; Chia-Jui Yen; Jaffer Ajani; Navtej S Buttar; Wei-Chao Chang; Chung-Hsuan Chen; Qingqing Ding; Jennifer L Hsu; Jung-Mao Hsu; Tzu-Hsuan Huang; Longfei Huo; Julie G Izzo; Adam M Labaff; Chien-Chen Lai; Jing-Yu Lang; Dung-Fang Lee; Chia-Wei Li; Dongping Liu; Stephanie A Miller; Fuu-Jen Tsai; Huamin Wang; Kenneth K Wang; Xuemei Wang; Mien-Chie Hung
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Cancer cell 2012;21(3):374-87.
2010: Jaffer A Ajani; Xuemei Wang; Julie G Izzo; Christopher H Crane; Cathy Eng; John M Skibber; Prajnan Das; Asif Rashid
Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation.
Digestive diseases and sciences 2010;55(4):1098-105.
2010: Soo Mi Kim; Yun-Yong Park; Eun Sung Park; Jae Yong Cho; Julie G Izzo; Di Zhang; Sang-Bae Kim; Jeffrey H Lee; Manoop S Bhutani; Stephen G Swisher; Xifeng Wu; Kevin R Coombes; Dipen Maru; Kenneth K Wang; Navtej S Buttar; Jaffer A Ajani; Ju-Seog Lee
Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome.
PloS one 2010;5(11):e15074.
2009: Jinliang Xing; Jaffer A Ajani; Meng Chen; Julie G Izzo; Jie Lin; Zhinan Chen; Jian Gu; Xifeng Wu
Constitutive short telomere length of chromosome 17p and 12q but not 11q and 2p is associated with an increased risk for esophageal cancer.
Cancer prevention research (Philadelphia, Pa.) 2009;2(5):459-65.
2009: Jennifer Pan; Jie Lin; Julie G Izzo; Yang Liu; Jinliang Xing; Maosheng Huang; Jaffer A Ajani; Xifeng Wu
Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.
Carcinogenesis 2009;30(5):785-92.
2009: Michelle A T Hildebrandt; Hushan Yang; Mien-Chie Hung; Julie G Izzo; Maosheng Huang; Jie Lin; Jaffer A Ajani; Xifeng Wu
Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(6):857-71.
2009: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Diane D Liu; Jeffrey L Myers; Tania L Ceron; Jan Lewin; William N William; Anthea Atwell; J Jack Lee; Ann M Gillenwater; Adel El-Naggar; Xifeng Wu; Scott M Lippman; Walter N Hittelman; Waun Ki Hong
Cyclin D1 and cancer development in laryngeal premalignancy patients.
Cancer prevention research (Philadelphia, Pa.) 2009;2(1):14-21.
2009: Julie G Izzo; Xifeng Wu; Tsung-Teh Wu; P Huang; Ju Seog Lee; Zhongxing Liao; Jeffrey H Lee; M S Bhutani; Wayne L Hofstetter; D Maru; Mien-Chie Hung; J A Ajani
Therapy-induced expression of NF-kappaB portends poor prognosis in patients with localized esophageal cancer undergoing preoperative chemoradiation.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2009;22(2):127-32.
2008: Heta Javeri; Rohan Arora; Arlene M Correa; Wayne L Hofstetter; Jeffrey H Lee; Zhongxing Liao; Mary F McAleer; Dipen Maru; Manoop S Bhutani; Stephen G Swisher; Julie G Izzo; Jaffer A Ajani
Influence of induction chemotherapy and class of cytotoxics on pathologic response and survival after preoperative chemoradiation in patients with carcinoma of the esophagus.
Cancer 2008;113(6):1302-8.
2008: Chia-Jui Yen; Julie G Izzo; Dung-Fang Lee; Sushovan Guha; Yongkun Wei; Tsung-Teh Wu; Chun-Te Chen; Hsu-Ping Kuo; Jung-Mao Hsu; Hui-Lung Sun; Chao-Kai Chou; Navtej S Buttar; Kenneth K Wang; Peng Huang; Jaffer Ajani; Mien-Chie Hung
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Cancer research 2008;68(8):2632-40.
2008: Y Yang; Marie Wislez; Nobukazu Fujimoto; Ludmila Prudkin; Julie G Izzo; Futoshi Uno; Lin Ji; Amy E Hanna; Robert R Langley; Diane Liu; Faye M Johnson; Ignacio I Wistuba; Jonathan M Kurie
A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras.
Molecular cancer therapeutics 2008;7(4):952-60.
2007: Pooja R Patel; Paul F Mansfield; Christopher H Crane; Tsung-Teh Wu; Jeffrey H Lee; Patrick M Lynch; Jeffrey Morris; Peter W T Pisters; Barry W Feig; Punita K Sunder; Julie G Izzo; Jaffer A Ajani
Clinical stage after preoperative chemoradiation is a better predictor of patient outcome than the baseline stage for localized gastric cancer.
Cancer 2007;110(5):989-95.
2007: Jennifer C Sims-Mourtada; Julie G Izzo; Jaffer A Ajani; K.S. Chao
Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport.
Oncogene 2007;26(38):5674-9.
2007: Yu-Jen Chen; Jennifer C Sims-Mourtada; Julie G Izzo; K.S. Chao
Targeting the hedgehog pathway to mitigate treatment resistance.
Cell cycle (Georgetown, Tex.) 2007;6(15):1826-30.
2007: Julie G Izzo; Usha Malhotra; Tsung-Teh Wu; Rajyalakshmi Luthra; Arlene M Correa; Stephen G Swisher; Wayne L Hofstetter; K.S. Chao; Mien-Chie Hung; Jaffer A Ajani
Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(6):1200-5.
2007: Julie G Izzo; Rajyalakshmi Luthra; Tsung-Teh Wu; Arlene M Correa; Madan G Luthra; Sharmila Anandasabapathy; K.S. Chao; Mien-Chie Hung; Bharat B Aggarwal; Walter N Hittelman; Jaffer A Ajani
Molecular mechanisms in Barrett's metaplasia and its progression.
Seminars in oncology 2007;34(2 Suppl 1):S2-6.
2007: Julie G Izzo; Tsung-Teh Wu; Xifeng Wu; Joe Ensor; Rajyalakshmi Luthra; Jennifer Pan; Arlene Correa; Stephen G Swisher; K.S. Chao; Walter N Hittelman; Jaffer A Ajani
Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(6):698-707.
2007: Madan G Luthra; Jaffer A Ajani; Julie G Izzo; Joe Ensor; Tsung-Teh Wu; Asif Rashid; LI Zhang; Alexandria Phan; Norio Fukami; Rajyalakshmi Luthra
Decreased expression of gene cluster at chromosome 1q21 defines molecular subgroups of chemoradiotherapy response in esophageal cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):912-9.
2006: Rajyalakshmi Luthra; Madan G Luthra; Julie G Izzo; Tsung-Teh Wu; Enrique Lopez-Alvarez; Usha Malhotra; In Seon Choi; LI Zhang; Jaffer A Ajani
Biomarkers of response to preoperative chemoradiation in esophageal cancers.
Seminars in oncology 2006;33(6 Suppl 11):S2-5.
2006: Julie G Izzo; Arlene M Correa; Tsung-Teh Wu; Usha Malhotra; K.S. Chao; Rajyalakshmi Luthra; Joe Ensor; Alexander Dekovich; Zhongxing Liao; Walter N Hittelman; Bharat B Aggarwal; Jaffer A Ajani
Pretherapy nuclear factor-kappaB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma.
Molecular cancer therapeutics 2006;5(11):2844-50.
2006: Jennifer C Sims-Mourtada; Julie G Izzo; Smith Apisarnthanarax; Tsung-Teh Wu; Usha Malhotra; Rajyalakshmi Luthra; Zhongxing Liao; Ritsuko Komaki; Albert J van der Kogel; Jaffer A Ajani; K.S. Chao
Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(21):6565-72.
2006: Marie Wislez; Nobukazu Fujimoto; Julie G Izzo; Amy E Hanna; Dianna D Cody; Robert R Langley; Hongli Tang; Marie D Burdick; Mitsuo Sato; John D Minna; Li Mao; Ignacio I Wistuba; Robert M Strieter; Jonathan M Kurie
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Cancer research 2006;66(8):4198-207.
2006: Julie G Izzo; Usha Malhotra; Tsung-Teh Wu; Joe Ensor; Rajyalakshmi Luthra; Jeffrey H Lee; Stephen G Swisher; Zhongxing Liao; K.S. Chao; Walter N Hittelman; Bharat B Aggarwal; Jaffer A Ajani
Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(5):748-54.
2006: Rajyalakshmi Luthra; Tsung-Teh Wu; Madan G Luthra; Julie G Izzo; Enrique Lopez-Alvarez; LI Zhang; Jaime Bailey; Jeffrey H Lee; Robert S Bresalier; Asif Rashid; Stephen G Swisher; Jaffer A Ajani
Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(2):259-67.
2005: Julie G Izzo; Usha Malhotra; Tseung T Wu; Joe Ensor; Ilona M Babenko; Stephen G Swisher; Arlene Correa; Robert S Bresalier; Walter N Hittelman; Jaffer A Ajani
Impact of cyclin D1 A870G polymorphism in esophageal adenocarcinoma tumorigenesis.
Seminars in oncology 2005;32(6 Suppl 9):S11-5.
2005: Jijiang Zhu; James L Abbruzzese; Julie G Izzo; Walter N Hittelman; Donghui Li
AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells.
Cancer genetics and cytogenetics 2005;159(1):10-7.
2005: Marie Wislez; M Loreto Spencer; Julie G Izzo; Denise M Juroske; Kamna Balhara; Dianna D Cody; Roger E Price; Walter N Hittelman; Ignacio I Wistuba; Jonathan M Kurie
Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Cancer research 2005;65(8):3226-35.
2005: Erminia Massarelli; Erika Brown; Ngoc K Tran; Diane D Liu; Julie G Izzo; J Jack Lee; Adel K El-Naggar; Waun Ki Hong; Vassiliki A Papadimitrakopoulou
Loss of E-cadherin and p27 expression is associated with head and neck squamous tumorigenesis.
Cancer 2005;103(5):952-9.
2003: Julie G Izzo; Vassiliki A Papadimitrakopoulou; Diane D Liu; Petra L C den Hollander; Ilona M Babenko; Jamie Keck; Adel K El-Naggar; Dong M Shin; J Jack Lee; Waun Ki Hong; Walter N Hittelman
Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer.
Journal of the National Cancer Institute 2003;95(3):198-205.
2001: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Li Mao; J Keck; D Hamilton; Dong M Shin; Adel El-Naggar; P den Hollander; Diane Liu; Walter N Hittelman; Waun Ki Hong
Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3127-34.
1998: Julie G Izzo; Vassiliki A Papadimitrakopoulou; X Q Li; Heladio Ibarguen; Jin S Lee; Jae Y Ro; Adel El-Naggar; Waun Ki Hong; Walter N Hittelman
Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification.
Oncogene 1998;17(18):2313-22.
1998: Vassiliki A Papadimitrakopoulou; Yun Oh; Adel El-Naggar; Julie G Izzo; Gary L Clayman; Li Mao
Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(3):539-44.
1997: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Scott M Lippman; Jin S Lee; You-Hong Fan; Gary L Clayman; Jae Y Ro; Walter N Hittelman; Reuben Lotan; Waun Ki Hong; Li Mao
Frequent inactivation of p16INK4a in oral premalignant lesions.
Oncogene 1997;14(15):1799-803.