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Tyler Jacks
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27
Bronson, Roderick
20
Crowley, Denise
17
Tuveson, David
13
Sage, Julien
11
Weinberg, Robert A.
11
Attardi, Laura
10
McLaughlin, Margaret
9
McClatchey, Andrea
8
Shannon, Kevin
7
de Vries, Annemieke
6
Flores, Elsa
6
Kissil, Joseph
6
Tsai, Kenneth
6
Mercer, Kim
6
Sweet-Cordero, Eric A.
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All Publications
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2009: Gidekel Friedlander Sharon Y; Chu Gerald C; Snyder Eric L; Girnius Nomeda; Dibelius Gregory; Crowley Denise; Vasile Eliza; DePinho Ronald A; Jacks Tyler
Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras.
Cancer cell 2009;16(5):379-89.
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2009: Meylan Etienne; Dooley Alison L; Feldser David M; Shen Lynn; Turk Erin; Ouyang Chensi; Jacks Tyler
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma.
Nature 2009;462(7269):104-7.
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2009: Lin Yu-Li; Sengupta Shomit; Gurdziel Katherine; Bell George W; Jacks Tyler; Flores Elsa R
p63 and p73 transcriptionally regulate genes involved in DNA repair.
PLoS genetics 2009;5(10):e1000680.
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2009: Yoon Sam S; Stangenberg Lars; Lee Yoon-Jin; Rothrock Courtney; Dreyfuss Jonathan M; Baek Kwan-Hyuck; Waterman Peter R; Nielsen G Petur; Weissleder Ralph; Mahmood Umar; Park Peter J; Jacks Tyler; Dodd Rebecca D; Fisher Carolyn J; Ryeom Sandra; Kirsch David G
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
International journal of radiation oncology, biology, physics 2009;74(4):1207-16.
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2009: Scholl Claudia; Fröhling Stefan; Dunn Ian F; Schinzel Anna C; Barbie David A; Kim So Young; Silver Serena J; Tamayo Pablo; Wadlow Raymond C; Ramaswamy Sridhar; Döhner Konstanze; Bullinger Lars; Sandy Peter; Boehm Jesse S; Root David E; Jacks Tyler; Hahn William C; Gilliland D Gary
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
Cell 2009;137(5):821-34.
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2009: Guttman Mitchell; Amit Ido; Garber Manuel; French Courtney; Lin Michael F; Feldser David; Huarte Maite; Zuk Or; Carey Bryce W; Cassady John P; Cabili Moran N; Jaenisch Rudolf; Mikkelsen Tarjei S; Jacks Tyler; Hacohen Nir; Bernstein Bradley E; Kellis Manolis; Regev Aviv; Rinn John L; Lander Eric S
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
Nature 2009;458(7235):223-7.
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2009: Ventura Andrea; Jacks Tyler
MicroRNAs and cancer: short RNAs go a long way.
Cell 2009;136(4):586-91.
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2009: DuPage Michel; Dooley Alison L; Jacks Tyler
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase.
Nature protocols 2009;4(7):1064-72.
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2008: Cheung Ann F; Dupage Michel J P; Dong H Katie; Chen Jianzhu; Jacks Tyler
Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer.
Cancer research 2008;68(22):9459-68.
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2008: Godar Samuel; Ince Tan A; Bell George W; Feldser David; Donaher Joana Liu; Bergh Jonas; Liu Anne; Miu Kevin; Watnick Randolph S; Reinhardt Ferenc; McAllister Sandra S; Jacks Tyler; Weinberg Robert A
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression.
Cell 2008;134(1):62-73.
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2008: Haigis Kevin M; Kendall Krystle R; Wang Yufang; Cheung Ann; Haigis Marcia C; Glickman Jonathan N; Niwa-Kawakita Michiko; Sweet-Cordero Alejandro; Sebolt-Leopold Judith; Shannon Kevin M; Settleman Jeffrey; Giovannini Marco; Jacks Tyler
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Nature genetics 2008;40(5):600-8.
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2008: Ventura Andrea; Young Amanda G; Winslow Monte M; Lintault Laura; Meissner Alex; Erkeland Stefan J; Newman Jamie; Bronson Roderick T; Crowley Denise; Stone James R; Jaenisch Rudolf; Sharp Phillip A; Jacks Tyler
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.
Cell 2008;132(5):875-86.
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2008: Kumar Madhu S; Erkeland Stefan J; Pester Ryan E; Chen Cindy Y; Ebert Margaret S; Sharp Phillip A; Jacks Tyler
Suppression of non-small cell lung tumor development by the let-7 microRNA family.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3903-8.
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2008: Coussens Lisa M; Jacks Tyler
Genetic and cellular mechanisms of oncogenesis.
Current opinion in genetics & development 2008;18(1):1-2.
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2008: Zhang Qing; Menon Rajasree; Deutsch Eric W; Pitteri Sharon J; Faca Vitor M; Wang Hong; Newcomb Lisa F; Depinho Ronald A; Bardeesy Nabeel; Dinulescu Daniela; Hung Kenneth E; Kucherlapati Raju; Jacks Tyler; Politi Katerina; Aebersold Ruedi; Omenn Gilbert S; States David J; Hanash Samir M
A mouse plasma peptide atlas as a resource for disease proteomics.
Genome biology 2008;9(6):R93.
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2007: Pandey Jyotsna; Umphress Sarah M; Kang Yang; Angdisen Jerry; Naumova Alena; Mercer Kim L; Jacks Tyler; Jakowlew Sonia B
Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency.
Carcinogenesis 2007;28(12):2589-96.
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2007: Kissil Joseph L; Walmsley Marita J; Hanlon Linda; Haigis Kevin M; Bender Kim Carla F; Sweet-Cordero Alejandro; Eckman Matthew S; Tuveson David A; Capobianco Anthony J; Tybulewicz Victor L J; Jacks Tyler
Requirement for Rac1 in a K-ras induced lung cancer in the mouse.
Cancer research 2007;67(17):8089-94.
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2007: Kirsch David G; Dinulescu Daniela M; Miller John B; Grimm Jan; Santiago Philip M; Young Nathan P; Nielsen G Petur; Quade Bradley J; Chaber Christopher J; Schultz Christian P; Takeuchi Osamu; Bronson Roderick T; Crowley Denise; Korsmeyer Stanley J; Yoon Sam S; Hornicek Francis J; Weissleder Ralph; Jacks Tyler
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Nature medicine 2007;13(8):992-7.
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2007: Zhang Jing; Liu Yangang; Beard Caroline; Tuveson David A; Jaenisch Rudolf; Jacks Tyler E; Lodish Harvey F
Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.
Blood 2007;109(12):5238-41.
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2007: Wijnhoven Susan W P; Speksnijder Ewoud N; Liu Xiaoling; Zwart Edwin; vanOostrom Conny Th M; Beems Rudolf B; Hoogervorst Esther M; Schaap Mirjam M; Attardi Laura D; Jacks Tyler; van Steeg Harry; Jonkers Jos; de Vries Annemieke
Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.
Cancer research 2007;67(10):4648-56.
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2007: Kumar Madhu S; Lu Jun; Mercer Kim L; Golub Todd R; Jacks Tyler
Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Nature genetics 2007;39(5):673-7.
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2007: Keller J W; Haigis K M; Franklin J L; Whitehead R H; Jacks T; Coffey R J
Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.
Oncogene 2007;26(21):3051-9.
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2007: Shaw Alice T; Meissner Alexander; Dowdle James A; Crowley Denise; Magendantz Margaret; Ouyang Chensi; Parisi Tiziana; Rajagopal Jayaraj; Blank Leah J; Bronson Roderick T; Stone James R; Tuveson David A; Jaenisch Rudolf; Jacks Tyler
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.
Genes & development 2007;21(6):694-707.
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2007: McLaughlin Margaret E; Kruger Genevieve M; Slocum Kelly L; Crowley Denise; Michaud Norman A; Huang Jennifer; Magendantz Margaret; Jacks Tyler
The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3261-6.
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2007: Ventura Andrea; Kirsch David G; McLaughlin Margaret E; Tuveson David A; Grimm Jan; Lintault Laura; Newman Jamie; Reczek Elizabeth E; Weissleder Ralph; Jacks Tyler
Restoration of p53 function leads to tumour regression in vivo.
Nature 2007;445(7128):661-5.
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2007: MacPherson David; Conkrite Karina; Tam Mandy; Mukai Shizuo; Mu David; Jacks Tyler
Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification.
The EMBO journal 2007;26(3):784-94.
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2006: Braun Benjamin S; Archard Joehleen A; Van Ziffle Jessica A G; Tuveson David A; Jacks Tyler E; Shannon Kevin
Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
Blood 2006;108(6):2041-4.
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2006: Charest Al; Wilker Erik W; McLaughlin Margaret E; Lane Keara; Gowda Ram; Coven Shanie; McMahon Kevin; Kovach Steven; Feng Yun; Yaffe Michael B; Jacks Tyler; Housman David
ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.
Cancer research 2006;66(15):7473-81.
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2006: To Minh D; Perez-Losada Jesus; Mao Jian-Hua; Hsu Jeff; Jacks Tyler; Balmain Allan
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
Nature genetics 2006;38(8):926-30.
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2006: Sweet-Cordero Alejandro; Tseng George C; You Han; Douglass Margaret; Huey Bing; Albertson Donna; Jacks Tyler
Comparison of gene expression and DNA copy number changes in a murine model of lung cancer.
Genes, chromosomes & cancer 2006;45(4):338-48.
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2006: Daikoku Takiko; Tranguch Susanne; Trofimova Irina N; Dinulescu Daniela M; Jacks Tyler; Nikitin Alexander Yu; Connolly Denise C; Dey Sudhansu K
Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.
Cancer research 2006;66(5):2527-31.
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2006: Tuveson David A; Zhu Liqin; Gopinathan Aarthi; Willis Nicholas A; Kachatrian Leili; Grochow Rebecca; Pin Christopher L; Mitin Natalia Y; Taparowsky Elizabeth J; Gimotty Phyllis A; Hruban Ralph H; Jacks Tyler; Konieczny Stephen F
Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma.
Cancer research 2006;66(1):242-7.
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2006: Haigis Kevin; Sage Julien; Glickman Jon; Shafer Sarah; Jacks Tyler
The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium.
The Journal of biological chemistry 2006;281(1):638-47.
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2005: Jackson Erica L; Olive Kenneth P; Tuveson David A; Bronson Roderick; Crowley Denise; Brown Michael; Jacks Tyler
The differential effects of mutant p53 alleles on advanced murine lung cancer.
Cancer research 2005;65(22):10280-8.
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2005: Chao Richard C; Pyzel Urszula; Fridlyand Jane; Kuo Yien-Ming; Teel Lewis; Haaga Jennifer; Borowsky Alexander; Horvai Andrew; Kogan Scott C; Bonifas Jeannette; Huey Bing; Jacks Tyler E; Albertson Donna G; Shannon Kevin M
Therapy-induced malignant neoplasms in Nf1 mutant mice.
Cancer cell 2005;8(4):337-48.
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2005: Grimm Jan; Kirsch David G; Windsor Stephen D; Kim Carla F Bender; Santiago Philip M; Ntziachristos Vasilis; Jacks Tyler; Weissleder Ralph
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(40):14404-9.
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2005: Wijnhoven Susan W P; Zwart Edwin; Speksnijder Ewoud N; Beems Rudolf B; Olive Kenneth P; Tuveson David A; Jonkers Jos; Schaap Mirjam M; van den Berg Jolanda; Jacks Tyler; van Steeg Harry; de Vries Annemieke
Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
Cancer research 2005;65(18):8166-73.
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2005: Kuns Robin; Kissil Joseph L; Newsham Irene F; Jacks Tyler; Gutmann David H; Sherman Larry S
Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation.
Oncogene 2005;24(43):6502-15.
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2005: Sandy Peter; Ventura Andrea; Jacks Tyler
Mammalian RNAi: a practical guide.
BioTechniques 2005;39(2):215-24.
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2005: Bono Petri; Cordero Etchell; Johnson Kristen; Borowsky Mark; Ramesh Vijaya; Jacks Tyler; Hynes Richard O
Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin.
Experimental cell research 2005;308(1):177-87.
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2005: Shaw Alice T; Kirsch David G; Jacks Tyler
Future of early detection of lung cancer: the role of mouse models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(13 Pt 2):4999s-5003s.
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2005: Kim Carla F Bender; Jackson Erica L; Woolfenden Amber E; Lawrence Sharon; Babar Imran; Vogel Sinae; Crowley Denise; Bronson Roderick T; Jacks Tyler
Identification of bronchioalveolar stem cells in normal lung and lung cancer.
Cell 2005;121(6):823-35.
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2005: Lu Jun; Getz Gad; Miska Eric A; Alvarez-Saavedra Ezequiel; Lamb Justin; Peck David; Sweet-Cordero Alejandro; Ebert Benjamin L; Mak Raymond H; Ferrando Adolfo A; Downing James R; Jacks Tyler; Horvitz H Robert; Golub Todd R
MicroRNA expression profiles classify human cancers.
Nature 2005;435(7043):834-8.
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2005: Hoogervorst Esther M; Bruins Wendy; Zwart Edwin; van Oostrom Conny Th M; van den Aardweg Gerard J; Beems Rudolf B; van den Berg Jolanda; Jacks Tyler; van Steeg Harry; de Vries Annemieke
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Cancer research 2005;65(9):3610-6.
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2005: Flores Elsa R; Sengupta Shomit; Miller John B; Newman Jamie J; Bronson Roderick; Crowley Denise; Yang Annie; McKeon Frank; Jacks Tyler
Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family.
Cancer cell 2005;7(4):363-73.
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2005: Dinulescu Daniela M; Ince Tan A; Quade Bradley J; Shafer Sarah A; Crowley Denise; Jacks Tyler
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer.
Nature medicine 2005;11(1):63-70.
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2005: Sweet-Cordero Alejandro; Mukherjee Sayan; Subramanian Aravind; You Han; Roix Jeffrey J; Ladd-Acosta Christine; Mesirov Jill; Golub Todd R; Jacks Tyler
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.
Nature genetics 2005;37(1):48-55.
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2005: Jacks Tyler
Modeling cancer in the mouse.
Harvey lectures 2005;101():1-19.
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2005: Jacks T
The beginning of the end of frustration.
Cold Spring Harbor symposia on quantitative biology 2005;70():525-8.
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2005: Kim C F B; Jackson E L; Kirsch D G; Grimm J; Shaw A T; Lane K; Kissil J; Olive K P; Sweet-Cordero A; Weissleder R; Jacks T
Mouse models of human non-small-cell lung cancer: raising the bar.
Cold Spring Harbor symposia on quantitative biology 2005;70():241-50.
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2004: Olive Kenneth P; Tuveson David A; Ruhe Zachary C; Yin Bob; Willis Nicholas A; Bronson Roderick T; Crowley Denise; Jacks Tyler
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.
Cell 2004;119(6):847-60.
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2004: Spike Benjamin T; Dirlam Alexandra; Dibling Benjamin C; Marvin James; Williams Bart O; Jacks Tyler; Macleod Kay F
The Rb tumor suppressor is required for stress erythropoiesis.
The EMBO journal 2004;23(21):4319-29.
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2004: Bruins Wendy; Zwart Edwin; Attardi Laura D; Iwakuma Tomoo; Hoogervorst Esther M; Beems Rudolf B; Miranda Barbara; van Oostrom Conny T M; van den Berg Jolanda; van den Aardweg Gerard J; Lozano Guillermina; van Steeg Harry; Jacks Tyler; de Vries Annemieke
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Molecular and cellular biology 2004;24(20):8884-94.
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2004: Iwakuma Tomoo; Parant John M; Fasulo Mark; Zwart Edwin; Jacks Tyler; de Vries Annemieke; Lozano Guillermina
Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
Oncogene 2004;23(46):7644-50.
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2004: MacPherson David; Kim Jungho; Kim Teresa; Rhee Byung Kirl; Van Oostrom Conny Th M; DiTullio Richard A; Venere Monica; Halazonetis Thanos D; Bronson Roderick; De Vries Annemieke; Fleming Mark; Jacks Tyler
Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.
The EMBO journal 2004;23(18):3689-99.
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2004: Reilly Karlyne M; Tuskan Robert G; Christy Emily; Loisel Dagan A; Ledger Jeremy; Bronson Roderick T; Smith C Dahlem; Tsang Shirley; Munroe David J; Jacks Tyler
Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):13008-13.
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2004: Ventura Andrea; Meissner Alexander; Dillon Christopher P; McManus Michael; Sharp Phillip A; Van Parijs Luk; Jaenisch Rudolf; Jacks Tyler
Cre-lox-regulated conditional RNA interference from transgenes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10380-5.
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2004: MacPherson David; Sage Julien; Kim Teresa; Ho Dennis; McLaughlin Margaret E; Jacks Tyler
Cell type-specific effects of Rb deletion in the murine retina.
Genes & development 2004;18(14):1681-94.
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2004: Mayhew Christopher N; Perkin Lisa M; Zhang Xiaoping; Sage Julien; Jacks Tyler; Knudsen Erik S
Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents.
Oncogene 2004;23(23):4107-20.
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2004: Tuveson David A; Shaw Alice T; Willis Nicholas A; Silver Daniel P; Jackson Erica L; Chang Sandy; Mercer Kim L; Grochow Rebecca; Hock Hanno; Crowley Denise; Hingorani Sunil R; Zaks Tal; King Catrina; Jacobetz Michael A; Wang Lifu; Bronson Roderick T; Orkin Stuart H; DePinho Ronald A; Jacks Tyler
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
Cancer cell 2004;5(4):375-87.
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2004: Nikitin Alexander Yu; Alcaraz Ana; Anver Miriam R; Bronson Roderick T; Cardiff Robert D; Dixon Darlene; Fraire Armando E; Gabrielson Edward W; Gunning William T; Haines Diana C; Kaufman Matthew H; Linnoila R Ilona; Maronpot Robert R; Rabson Alan S; Reddick Robert L; Rehm Sabine; Rozengurt Nora; Schuller Hildegard M; Shmidt Elena N; Travis William D; Ward Jerrold M; Jacks Tyler
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.
Cancer research 2004;64(7):2307-16.
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2004: Chan Iris T; Kutok Jeffery L; Williams Ifor R; Cohen Sarah; Kelly Lauren; Shigematsu Hirokazu; Johnson Leisa; Akashi Koichi; Tuveson David A; Jacks Tyler; Gilliland D Gary
Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.
The Journal of clinical investigation 2004;113(4):528-38.
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2004: Attardi Laura D; de Vries Annemieke; Jacks Tyler
Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer.
Oncogene 2004;23(4):973-80.
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2004: Braun Benjamin S; Tuveson David A; Kong Namie; Le Doan T; Kogan Scott C; Rozmus Jacob; Le Beau Michelle M; Jacks Tyler E; Shannon Kevin M
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):597-602.
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2004: Bosco Emily E; Mayhew Christopher N; Hennigan Robert F; Sage Julien; Jacks Tyler; Knudsen Erik S
RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult.
Nucleic acids research 2004;32(1):25-34.
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2003: Reczek Elizabeth E; Flores Elsa R; Tsay Alice S; Attardi Laura D; Jacks Tyler
Multiple response elements and differential p53 binding control Perp expression during apoptosis.
Molecular cancer research : MCR 2003;1(14):1048-57.
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2003: Hingorani Sunil R; Petricoin Emanuel F; Maitra Anirban; Rajapakse Vinodh; King Catrina; Jacobetz Michael A; Ross Sally; Conrads Thomas P; Veenstra Timothy D; Hitt Ben A; Kawaguchi Yoshiya; Johann Don; Liotta Lance A; Crawford Howard C; Putt Mary E; Jacks Tyler; Wright Christopher V E; Hruban Ralph H; Lowy Andrew M; Tuveson David A
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Cancer cell 2003;4(6):437-50.
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2003: Balsitis Scott J; Sage Julien; Duensing Stefan; Münger Karl; Jacks Tyler; Lambert Paul F
Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo.
Molecular and cellular biology 2003;23(24):9094-103.
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2003: Ihrie Rebecca A; Reczek Elizabeth; Horner Jennifer S; Khachatrian Leili; Sage Julien; Jacks Tyler; Attardi Laura D
Perp is a mediator of p53-dependent apoptosis in diverse cell types.
Current biology : CB 2003;13(22):1985-90.
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2003: Kissil Joseph L; Wilker Erik W; Johnson Kristen C; Eckman Matthew S; Yaffe Michael B; Jacks Tyler
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
Molecular cell 2003;12(4):841-9.
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2003: Minna John D; Kurie Jonathan M; Jacks Tyler
A big step in the study of small cell lung cancer.
Cancer cell 2003;4(3):163-6.
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2003: Karlseder Jan; Kachatrian Leili; Takai Hiroyuki; Mercer Kim; Hingorani Sunil; Jacks Tyler; de Lange Titia
Targeted deletion reveals an essential function for the telomere length regulator Trf1.
Molecular and cellular biology 2003;23(18):6533-41.
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2003: McLaughlin Margaret E; Robson Caroline D; Kieran Mark W; Jacks Tyler; Pomeroy Scott L; Cameron Scott
Marked regression of metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec): a case report and laboratory investigation.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2003;25(8):644-8.
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2003: Takahashi Chiaki; Bronson Roderick T; Socolovsky Merav; Contreras Bernardo; Lee Kwang Youl; Jacks Tyler; Noda Makoto; Kucherlapati Raju; Ewen Mark E
Rb and N-ras function together to control differentiation in the mouse.
Molecular and cellular biology 2003;23(15):5256-68.
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2003: Sage Julien; Miller Abigail L; Pérez-Mancera Pedro A; Wysocki Julianne M; Jacks Tyler
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry.
Nature 2003;424(6945):223-8.
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2003: Cichowski Karen; Santiago Sabrina; Jardim Melanie; Johnson Bryan W; Jacks Tyler
Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor.
Genes & development 2003;17(4):449-54.
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2003: McLaughlin Margaret E; Jacks Tyler
Progesterone receptor expression in neurofibromas.
Cancer research 2003;63(4):752-5.
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2003: MacPherson D; Sage J; Crowley D; Trumpp A; Bronson R T; Jacks T
Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.
Molecular and cellular biology 2003;23(3):1044-53.
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2003: McLaughlin Margaret E; Jacks Tyler
Neurofibromatosis type 1.
Methods in molecular biology (Clifton, N.J.) 2003;222():223-37.
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2002: Jacks Tyler; Weinberg Robert A
Taking the study of cancer cell survival to a new dimension.
Cell 2002;111(7):923-5.
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2002: Tsai Kenneth Y; MacPherson David; Rubinson Douglas A; Nikitin Alexander Yu; Bronson Roderick; Mercer Kim L; Crowley Denise; Jacks Tyler
ARF mutation accelerates pituitary tumor development in Rb+/- mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16865-70.
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2002: Lee Ho-Young; Suh Young-Ah; Lee Janet I; Hassan Khaled A; Mao Li; Force Thomas; Gilbert Brian E; Jacks Tyler; Kurie Jonathan M
Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2970-5.
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2002: Johnson Kristen C; Kissil Joseph L; Fry Jessica L; Jacks Tyler
Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene.
Oncogene 2002;21(39):5990-7.
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2002: McLaughlin Margaret E; Jacks Tyler
Thinking beyond the tumor cell: Nf1 haploinsufficiency in the tumor environment.
Cancer cell 2002;1(5):408-10.
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2002: Yang Hong; Williams Bart O; Hinds Phillip W; Shih T Shane; Jacks Tyler; Bronson Roderick T; Livingston David M
Tumor suppression by a severely truncated species of retinoblastoma protein.
Molecular and cellular biology 2002;22(9):3103-10.
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2002: Klappacher Günter W; Lunyak Victoria V; Sykes David B; Sawka-Verhelle Dominique; Sage Julien; Brard Gyan; Ngo Sally D; Gangadharan Denise; Jacks Tyler; Kamps Mark P; Rose David W; Rosenfeld Michael G; Glass Christopher K
An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation.
Cell 2002;109(2):169-80.
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2002: Flores Elsa R; Tsai Kenneth Y; Crowley Denise; Sengupta Shomit; Yang Annie; McKeon Frank; Jacks Tyler
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.
Nature 2002;416(6880):560-4.
-
2002: de Vries Annemieke; Flores Elsa R; Miranda Barbara; Hsieh Harn-Mei; van Oostrom Conny Th M; Sage Julien; Jacks Tyler
Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2948-53.
-
2002: Kissil Joseph L; Johnson Kristen C; Eckman Matthew S; Jacks Tyler
Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization.
The Journal of biological chemistry 2002;277(12):10394-9.
-
2002: Kim Tae Jin; Cariappa Annaiah; Iacomini John; Tang Mei; Shih Shane; Bernards Andre; Jacks Tyler; Pillai Shiv
Defective proliferative responses in B lymphocytes and thymocytes that lack neurofibromin.
Molecular immunology 2002;38(9):701-8.
-
2002: Tuveson David A; Jacks Tyler
Technologically advanced cancer modeling in mice.
Current opinion in genetics & development 2002;12(1):105-10.
-
2002: Van Dyke Terry; Jacks Tyler
Cancer modeling in the modern era: progress and challenges.
Cell 2002;108(2):135-44.
-
2002: Tsai Kenneth Y; MacPherson David; Rubinson Douglas A; Crowley Denise; Jacks Tyler
ARF is not required for apoptosis in Rb mutant mouse embryos.
Current biology : CB 2002;12(2):159-63.
-
2002: Costa Rui M; Federov Nikolai B; Kogan Jeff H; Murphy Geoffrey G; Stern Joel; Ohno Masuo; Kucherlapati Raju; Jacks Tyler; Silva Alcino J
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Nature 2002;415(6871):526-30.
-
2001: Jackson E L; Willis N; Mercer K; Bronson R T; Crowley D; Montoya R; Jacks T; Tuveson D A
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.
Genes & development 2001;15(24):3243-8.
-
2001: Tuveson D A; Willis N A; Jacks T; Griffin J D; Singer S; Fletcher C D; Fletcher J A; Demetri G D
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications.
Oncogene 2001;20(36):5054-8.
-
2001: Shaw R J; Paez J G; Curto M; Yaktine A; Pruitt W M; Saotome I; O'Bryan J P; Gupta V; Ratner N; Der C J; Jacks T; McClatchey A I
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
Developmental cell 2001;1(1):63-72.
-
2001: Lipinski M M; Macleod K F; Williams B O; Mullaney T L; Crowley D; Jacks T
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
The EMBO journal 2001;20(13):3402-13.
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2001: Johnson L; Mercer K; Greenbaum D; Bronson R T; Crowley D; Tuveson D A; Jacks T
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.
Nature 2001;410(6832):1111-6.
-
2001: Cichowski K; Jacks T
NF1 tumor suppressor gene function: narrowing the GAP.
Cell 2001;104(4):593-604.
-
2000: Sage J; Mulligan G J; Attardi L D; Miller A; Chen S; Williams B; Theodorou E; Jacks T
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.
Genes & development 2000;14(23):3037-50.
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2000: Wang Y; Hayward S W; Donjacour A A; Young P; Jacks T; Sage J; Dahiya R; Cardiff R D; Day M L; Cunha G R
Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue.
Cancer research 2000;60(21):6008-17.
-
2000: Irwin M; Marin M C; Phillips A C; Seelan R S; Smith D I; Liu W; Flores E R; Tsai K Y; Jacks T; Vousden K H; Kaelin W G
Role for the p53 homologue p73 in E2F-1-induced apoptosis.
Nature 2000;407(6804):645-8.
-
2000: Boyd S D; Tsai K Y; Jacks T
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.
Nature cell biology 2000;2(9):563-8.
-
2000: Reilly K M; Loisel D A; Bronson R T; McLaughlin M E; Jacks T
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects.
Nature genetics 2000;26(1):109-13.
-
2000: Lim D J; Rubenstein A E; Evans D G; Jacks T; Seizinger B G; Baser M E; Beebe D; Brackmann D E; Chiocca E A; Fehon R G; Giovannini M; Glazer R; Gusella J F; Gutmann D H; Korf B; Lieberman F; Martuza R; McClatchey A I; Parry D M; Pulst S M; Ramesh V; Ramsey W J; Ratner N; Rutkowski J L; Ruttledge M; Weinstein D E
Advances in neurofibromatosis 2 (NF2): a workshop report.
Journal of neurogenetics 2000;14(2):63-106.
-
2000: Zhang Y; Griffith E C; Sage J; Jacks T; Liu J O
Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6427-32.
-
2000: Attardi L D; Reczek E E; Cosmas C; Demicco E G; McCurrach M E; Lowe S W; Jacks T
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.
Genes & development 2000;14(6):704-18.
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2000: Birnbaum R A; O'Marcaigh A; Wardak Z; Zhang Y Y; Dranoff G; Jacks T; Clapp D W; Shannon K M
Nf1 and Gmcsf interact in myeloid leukemogenesis.
Molecular cell 2000;5(1):189-95.
-
1999: Lipinski M M; Jacks T
The retinoblastoma gene family in differentiation and development.
Oncogene 1999;18(55):7873-82.
-
1999: Cichowski K; Shih T S; Schmitt E; Santiago S; Reilly K; McLaughlin M E; Bronson R T; Jacks T
Mouse models of tumor development in neurofibromatosis type 1.
Science (New York, N.Y.) 1999;286(5447):2172-6.
-
1999: Mahgoub N; Taylor B R; Gratiot M; Kohl N E; Gibbs J B; Jacks T; Shannon K M
In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells.
Blood 1999;94(7):2469-76.
-
1999: de Lange T; Jacks T
For better or worse? Telomerase inhibition and cancer.
Cell 1999;98(3):273-5.
-
1999: Mahgoub N; Taylor B R; Le Beau M M; Gratiot M; Carlson K M; Atwater S K; Jacks T; Shannon K M
Myeloid malignancies induced by alkylating agents in Nf1 mice.
Blood 1999;93(11):3617-23.
-
1999: Brugarolas J; Moberg K; Boyd S D; Taya Y; Jacks T; Lees J A
Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):1002-7.
-
1999: Attardi L D; Jacks T
The role of p53 in tumour suppression: lessons from mouse models.
Cellular and molecular life sciences : CMLS 1999;55(1):48-63.
-
1998: Tsai K Y; Hu Y; Macleod K F; Crowley D; Yamasaki L; Jacks T
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos.
Molecular cell 1998;2(3):293-304.
-
1998: McClatchey A I; Jacks T
Tumor suppressor mutations in mice: the next generation.
Current opinion in genetics & development 1998;8(3):304-10.
-
1998: Mulligan G; Jacks T
The retinoblastoma gene family: cousins with overlapping interests.
Trends in genetics : TIG 1998;14(6):223-9.
-
1998: Zhang Y Y; Vik T A; Ryder J W; Srour E F; Jacks T; Shannon K; Clapp D W
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines.
The Journal of experimental medicine 1998;187(11):1893-902.
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1998: Jacks T; Weinberg R A
The expanding role of cell cycle regulators.
Science (New York, N.Y.) 1998;280(5366):1035-6.
-
1998: Zamble D B; Jacks T; Lippard S J
p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6163-8.
-
1998: Shaw R J; McClatchey A I; Jacks T
Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(4):287-96.
-
1998: McClatchey A I; Saotome I; Mercer K; Crowley D; Gusella J F; Bronson R T; Jacks T
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
Genes & development 1998;12(8):1121-33.
-
1998: Brugarolas J; Bronson R T; Jacks T
p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells.
The Journal of cell biology 1998;141(2):503-14.
-
1998: Yamasaki L; Bronson R; Williams B O; Dyson N J; Harlow E; Jacks T
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice.
Nature genetics 1998;18(4):360-4.
-
1998: Shaw R J; McClatchey A I; Jacks T
Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli.
The Journal of biological chemistry 1998;273(13):7757-64.
-
1998: Nacht M; Jacks T
V(D)J recombination is not required for the development of lymphoma in p53-deficient mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(2):131-8.
-
1998: Shaw R J; Henry M; Solomon F; Jacks T
RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts.
Molecular biology of the cell 1998;9(2):403-19.
-
1998: Mulligan G J; Wong J; Jacks T
p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.
Molecular and cellular biology 1998;18(1):206-20.
-
1997: Johnson L; Greenbaum D; Cichowski K; Mercer K; Murphy E; Schmitt E; Bronson R T; Umanoff H; Edelmann W; Kucherlapati R; Jacks T
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
Genes & development 1997;11(19):2468-81.
-
1997: Lanni J S; Lowe S W; Licitra E J; Liu J O; Jacks T
p53-independent apoptosis induced by paclitaxel through an indirect mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9679-83.
-
1997: Jones J M; Attardi L; Godley L A; Laucirica R; Medina D; Jacks T; Varmus H E; Donehower L A
Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(8):829-38.
-
1997: McClatchey A I; Saotome I; Ramesh V; Gusella J F; Jacks T
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
Genes & development 1997;11(10):1253-65.
-
1996: Macleod K F; Hu Y; Jacks T
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system.
The EMBO journal 1996;15(22):6178-88.
-
1996: Cichowski K; Shih T S; Jacks T
Nf1 gene targeting: toward models and mechanisms.
Seminars in cancer biology 1996;7(5):291-8.
-
1996: Nacht M; Strasser A; Chan Y R; Harris A W; Schlissel M; Bronson R T; Jacks T
Mutations in the p53 and SCID genes cooperate in tumorigenesis.
Genes & development 1996;10(16):2055-66.
-
1996: Attardi L D; Lowe S W; Brugarolas J; Jacks T
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis.
The EMBO journal 1996;15(14):3693-701.
-
1996: Cobrinik D; Lee M H; Hannon G; Mulligan G; Bronson R T; Dyson N; Harlow E; Beach D; Weinberg R A; Jacks T
Shared role of the pRB-related p130 and p107 proteins in limb development.
Genes & development 1996;10(13):1633-44.
-
1996: Lee M H; Williams B O; Mulligan G; Mukai S; Bronson R T; Dyson N; Harlow E; Jacks T
Targeted disruption of p107: functional overlap between p107 and Rb.
Genes & development 1996;10(13):1621-32.
-
1996: Yamasaki L; Jacks T; Bronson R; Goillot E; Harlow E; Dyson N J
Tumor induction and tissue atrophy in mice lacking E2F-1.
Cell 1996;85(4):537-48.
-
1996: Herrera R E; Sah V P; Williams B O; Mäkelä T P; Weinberg R A; Jacks T
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.
Molecular and cellular biology 1996;16(5):2402-7.
-
1996: Lehar S M; Nacht M; Jacks T; Vater C A; Chittenden T; Guild B C
Identification and cloning of EI24, a gene induced by p53 in etoposide-treated cells.
Oncogene 1996;12(6):1181-7.
-
1996: Williams B O; Jacks T
Mechanisms of carcinogenesis and the mutant mouse.
Current opinion in genetics & development 1996;6(1):65-70.
-
1995: Brugarolas J; Chandrasekaran C; Gordon J I; Beach D; Jacks T; Hannon G J
Radiation-induced cell cycle arrest compromised by p21 deficiency.
Nature 1995;377(6549):552-7.
-
1995: Mombaerts P; Terhorst C; Jacks T; Tonegawa S; Sancho J
Characterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7420-4.
-
1995: Sah V P; Attardi L D; Mulligan G J; Williams B O; Bronson R T; Jacks T
A subset of p53-deficient embryos exhibit exencephaly.
Nature genetics 1995;10(2):175-80.
-
1995: Macleod K F; Sherry N; Hannon G; Beach D; Tokino T; Kinzler K; Vogelstein B; Jacks T
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.
Genes & development 1995;9(8):935-44.
-
1994: Ziegler A; Jonason A S; Leffell D J; Simon J A; Sharma H W; Kimmelman J; Remington L; Jacks T; Brash D E
Sunburn and p53 in the onset of skin cancer.
Nature 1994;372(6508):773-6.
-
1994: Lowe S W; Bodis S; McClatchey A; Remington L; Ruley H E; Fisher D E; Housman D E; Jacks T
p53 status and the efficacy of cancer therapy in vivo.
Science (New York, N.Y.) 1994;266(5186):807-10.
-
1994: Morgenbesser S D; Williams B O; Jacks T; DePinho R A
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
Nature 1994;371(6492):72-4.
-
1994: Williams B O; Schmitt E M; Remington L; Bronson R T; Albert D M; Weinberg R A; Jacks T
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences.
The EMBO journal 1994;13(18):4251-9.
-
1994: Symonds H; Krall L; Remington L; Saenz-Robles M; Lowe S; Jacks T; Van Dyke T
p53-dependent apoptosis suppresses tumor growth and progression in vivo.
Cell 1994;78(4):703-11.
-
1994: Williams B O; Remington L; Albert D M; Mukai S; Bronson R T; Jacks T
Cooperative tumorigenic effects of germline mutations in Rb and p53.
Nature genetics 1994;7(4):480-4.
-
1994: Jacks T; Shih T S; Schmitt E M; Bronson R T; Bernards A; Weinberg R A
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1.
Nature genetics 1994;7(3):353-61.
-
1994: Slebos R J; Lee M H; Plunkett B S; Kessis T D; Williams B O; Jacks T; Hedrick L; Kastan M B; Cho K R
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5320-4.
-
1994: Lowe S W; Jacks T; Housman D E; Ruley H E
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2026-30.
-
1994: Jacks T; Remington L; Williams B O; Schmitt E M; Halachmi S; Bronson R T; Weinberg R A
Tumor spectrum analysis in p53-mutant mice.
Current biology : CB 1994;4(1):1-7.
-
1994: Williams B O; Morgenbesser S D; DePinho R A; Jacks T
Tumorigenic and developmental effects of combined germ-line mutations in Rb and p53.
Cold Spring Harbor symposia on quantitative biology 1994;59():449-57.
-
1994: Lowe S W; Bodis S; Bardeesy N; McClatchey A; Remington L; Ruley H E; Fisher D E; Jacks T; Pelletier J; Housman D E
Apoptosis and the prognostic significance of p53 mutation.
Cold Spring Harbor symposia on quantitative biology 1994;59():419-26.
-
1994: Symonds H; Krall L; Remington L; Sáenz Robles M; Jacks T; Van Dyke T
p53-dependent apoptosis in vivo: impact of p53 inactivation on tumorigenesis.
Cold Spring Harbor symposia on quantitative biology 1994;59():247-57.
-
1994: Hatakeyama M; Herrera R A; Makela T; Dowdy S F; Jacks T; Weinberg R A
The cancer cell and the cell cycle clock.
Cold Spring Harbor symposia on quantitative biology 1994;59():1-10.
-
1993: Cobrinik D; Whyte P; Peeper D S; Jacks T; Weinberg R A
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
Genes & development 1993;7(12A):2392-404.
-
1993: Berges R R; Furuya Y; Remington L; English H F; Jacks T; Isaacs J T
Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8910-4.
-
1993: Lowe S W; Ruley H E; Jacks T; Housman D E
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents.
Cell 1993;74(6):957-67.
-
1993: Lowe S W; Schmitt E M; Smith S W; Osborne B A; Jacks T
p53 is required for radiation-induced apoptosis in mouse thymocytes.
Nature 1993;362(6423):847-9.
-
1992: Kastan M B; Zhan Q; el-Deiry W S; Carrier F; Jacks T; Walsh W V; Plunkett B S; Vogelstein B; Fornace A J
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.
Cell 1992;71(4):587-97.
-
1992: Jacks T; Fazeli A; Schmitt E M; Bronson R T; Goodell M A; Weinberg R A
Effects of an Rb mutation in the mouse.
Nature 1992;359(6393):295-300.
-
1988: Jacks T; Madhani H D; Masiarz F R; Varmus H E
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region.
Cell 1988;55(3):447-58.
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