FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Stephen Jackson

Research Profile

Chemicals & Drugs

Physiology

Disorders

Co-author Network

Publications

TOP 3
Christine K Schmidt; Stephen P Jackson
On Your MARK, Get SET(D2), Go! H3K36me3 Primes DNA Mismatch Repair.
Richard Chahwan; Serge Gravel; Takahiro Matsusaka; Stephen P Jackson
RNF8 links nucleosomal and cytoskeletal ubiquitylation of higher order protein structures.
Richard Chahwan; Serge Gravel; Takahiro Matsusaka; Stephen P Jackson
Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Stephen Jackson (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Christine K Schmidt; Stephen P Jackson
On Your MARK, Get SET(D2), Go! H3K36me3 Primes DNA Mismatch Repair.
Cell 2013;153(3):513-5.
2013: Richard Chahwan; Serge Gravel; Takahiro Matsusaka; Stephen P Jackson
RNF8 links nucleosomal and cytoskeletal ubiquitylation of higher order protein structures.
Cell cycle (Georgetown, Tex.) 2013;12(8):1161.
2013: Richard Chahwan; Serge Gravel; Takahiro Matsusaka; Stephen P Jackson
Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins.
Cell cycle (Georgetown, Tex.) 2013;12(6):1000-8.
2013: Stephen P Jackson; Daniel Durocher
Regulation of DNA damage responses by ubiquitin and SUMO.
Molecular cell 2013;49(5):795-807.
2013: Abdeladim Moumen; Christine Magill; Katherine L Dry; Stephen P Jackson
ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage.
Cell cycle (Georgetown, Tex.) 2013;12(4):698-704.
2013: Sandra Muñoz-Galván; Felipe Cortés-Ledesma; Pablo Huertas; Stephen P Jackson; Ana López-Saavedra; Andrés Aguilera
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.
Nucleic acids research 2013;41(3):1669-83.
2012: Josep V Forment; Abderrahmane Kaidi; Stephen P Jackson
Chromothripsis and cancer: causes and consequences of chromosome shattering.
Nature reviews. Cancer 2012;12(10):663-70.
2012: Josep V Forment; Rachael V Walker; Stephen P Jackson
A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(10):922-8.
2012: J Ross Chapman; Simon J Boulton; Alex J Sossick; Stephen P Jackson
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
Journal of cell science 2012;125(Pt 15):3529-34.
2012: Yaron Galanty; Rimma Belotserkovskaya; Julia Coates; Stephen P Jackson
RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.
Genes & development 2012;26(11):1179-95.
2012: Jacob Falck; Josep V Forment; Jiri Bartek; Julia Coates; Jiri Lukas; Martin Mistrik; Stephen P Jackson
CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination.
EMBO reports 2012;13(6):561-8.
2012: Petra Beli; Linda Baskcomb; Stephen P Jackson; Natalia Lukashchuk; Matthias Mann; Jesper V Olsen; Sebastian A Wagner; Brian T Weinert; Chunaram Choudhary
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
Molecular cell 2012;46(2):212-25.
2012: Kyle M Miller; Stephen P Jackson
Histone marks: repairing DNA breaks within the context of chromatin.
Biochemical Society transactions 2012;40(2):370-6.
2012: Raphaël Rodriguez; Blerta Xhemalce; Kyle M Miller; Mehran Nikan; Tobias Oelschlaegel; Shankar Balasubramanian; Charles R Bradshaw; Sébastien Britton; Josep V Forment; Stephen P Jackson
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Nature chemical biology 2012;8(3):301-10.
2012: Sophie E Polo; Andre Rusch; Philippa Smith; Grant S Stewart; A Malcolm R Taylor; Anoushka Thomas; Andrew S Turnell; Julia Kzhyshkowska; Linda Baskcomb; Andrew N Blackford; Rachel Blundred; J Ross Chapman; Thomas Dobner; Roger J Grand; Serge Gravel; Stephen P Jackson
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.
Molecular cell 2012;45(4):505-16.
2011: Sonja Flott; Youngho Kwon; Ying Zhang Pigli; Phoebe A Rice; Patrick Sung; Stephen P Jackson
Regulation of Rad51 function by phosphorylation.
EMBO reports 2011;12(8):833-9.
2011: Simona Giunta; Stephen P Jackson
Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events.
Cell cycle (Georgetown, Tex.) 2011;10(8):1215-21.
2011: Jeanine A Harrigan; Rimma Belotserkovskaya; Julia Coates; Daniela S Dimitrova; Sophie E Polo; Charles R Bradshaw; Peter Fraser; Stephen P Jackson
Replication stress induces 53BP1-containing OPT domains in G1 cells.
The Journal of cell biology 2011;193(1):97-108.
2011: Josep V Forment; Ilaria Guerini; Melanie Blasius; Stephen P Jackson
Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation.
PloS one 2011;6(8):e23517.
2011: Melanie Blasius; Chunaram Choudhary; Josep V Forment; Neha Thakkar; Sebastian A Wagner; Stephen P Jackson
A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.
Genome biology 2011;12(8):R78.
2010: Sophie E Polo; Abderrahmane Kaidi; Linda Baskcomb; Yaron Galanty; Stephen P Jackson
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4.
The EMBO journal 2010;29(18):3130-9.
2010: Abderrahmane Kaidi; Brian T Weinert; Chunaram Choudhary; Stephen P Jackson
Human SIRT6 promotes DNA end resection through CtIP deacetylation.
Science (New York, N.Y.) 2010;329(5997):1348-53.
2010: Kyle M Miller; Jorrit V Tjeertes; Julia Coates; Gaëlle Legube; Sophie E Polo; Sébastien Britton; Stephen P Jackson
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.
Nature structural & molecular biology 2010;17(9):1144-51.
2010: Simona Giunta; Rimma Belotserkovskaya; Stephen P Jackson
DNA damage signaling in response to double-strand breaks during mitosis.
The Journal of cell biology 2010;190(2):197-207.
2010: Petra Hajkova; Sean J Jeffries; Caroline Lee; Nigel Miller; Stephen P Jackson; M Azim Surani
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway.
Science (New York, N.Y.) 2010;329(5987):78-82.
2009: Yaron Galanty; Rimma Belotserkovskaya; Julia Coates; Sophie Polo; Kyle M Miller; Stephen P Jackson
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
Nature 2009;462(7275):935-9.
2009: Stephen P Jackson; Jiri Bartek
The DNA-damage response in human biology and disease.
Nature 2009;461(7267):1071-8.
2009: Janette Lloyd; J Ross Chapman; Julie A Clapperton; Lesley F Haire; Edgar Hartsuiker; Jiejin Li; Antony M Carr; Stephen P Jackson; Stephen John Smerdon
A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.
Cell 2009;139(1):100-11.
2009: Jorrit V Tjeertes; Kyle M Miller; Stephen P Jackson
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells.
The EMBO journal 2009;28(13):1878-89.
2009: Stephen P Jackson
The DNA-damage response: new molecular insights and new approaches to cancer therapy.
Biochemical Society transactions 2009;37(Pt 3):483-94.
2009: Pablo Huertas; Stephen P Jackson
Human CtIP mediates cell cycle control of DNA end resection and double strand break repair.
The Journal of biological chemistry 2009;284(14):9558-65.
2009: Martin Enge; Wenjie Bao; Elisabeth Hedström; Stephen P Jackson; Abdeladim Moumen; Galina Selivanova
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53.
Cancer cell 2009;15(3):171-83.
2008: Serge Gravel; J Ross Chapman; Christine Magill; Stephen P Jackson
DNA helicases Sgs1 and BLM promote DNA double-strand break resection.
Genes & development 2008;22(20):2767-72.
2008: Pablo Huertas; Felipe Cortés-Ledesma; Alessandro Sartori; Andres Aguilera; Stephen P Jackson
CDK targets Sae2 to control DNA-end resection and homologous recombination.
Nature 2008;455(7213):689-92.
2008: J Ross Chapman; Stephen P Jackson
Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage.
EMBO reports 2008;9(8):795-801.
2008: Yi Li; Dimitri Y Chirgadze; Victor Martin Bolanos-Garcia; Bancinyane L Sibanda; Owen Richard Davies; Peter Ahnesorg; Stephen P Jackson; Tom L Blundell
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
The EMBO journal 2008;27(1):290-300.
2007: Alessandro Sartori; Claudia Lukas; Julia Coates; Martin Mistrik; Shuang Fu; Jiri Bartek; Richard Baer; Jiri Lukas; Stephen P Jackson
Human CtIP promotes DNA end resection.
Nature 2007;450(7169):509-14.
2007: Andrew Hammet; Christine Magill; Jörg Heierhorst; Stephen P Jackson
Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast.
EMBO reports 2007;8(9):851-7.
2007: Andreas Meier; Heike Fiegler; Purificacion Muñoz; Peter Ellis; Diane Rigler; Cordelia Langford; Maria A Blasco; Nigel Carter; Stephen P Jackson
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres.
The EMBO journal 2007;26(11):2707-18.
2007: Peter Ahnesorg; Stephen P Jackson
The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint.
DNA repair 2007;6(2):190-201.
2007: Robert Driscoll; Amanda Hudson; Stephen P Jackson
Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56.
Science (New York, N.Y.) 2007;315(5812):649-52.
2006: Pierre Hentges; Peter Ahnesorg; Robert S Pitcher; Christopher Bruce; Boris Kysela; Andrew J Green; Julie Bianchi; Thomas E Wilson; Stephen P Jackson; Aidan J Doherty
Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos.
The Journal of biological chemistry 2006;281(49):37517-26.
2006: Muriel Grenon; Christine P Magill; Noel F Lowndes; Stephen P Jackson
Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.
FEMS yeast research 2006;6(5):836-47.
2006: Andrew S Doré; Nicholas Furnham; Owen Richard Davies; Bancinyane L Sibanda; Dimitri Y Chirgadze; Stephen P Jackson; Luca Pellegrini; Tom L Blundell
Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA repair 2006;5(3):362-8.
2006: Peter Ahnesorg; Philippa Smith; Stephen P Jackson
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.
Cell 2006;124(2):301-13.
2006: Veronique A J Smits; Philip M Reaper; Stephen P Jackson
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.
Current biology : CB 2006;16(2):150-9.
2006: Ali Jazayeri; Jacob Falck; Claudia Lukas; Jiri Bartek; Graeme C M Smith; Jiri Lukas; Stephen P Jackson
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.
Nature cell biology 2006;8(1):37-45.
2005: Manuel Stucki; Julie A Clapperton; Duaa Mohammad; Michael B Yaffe; Stephen John Smerdon; Stephen P Jackson
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
Cell 2005;123(7):1213-26.
2005: Abdeladim Moumen; Philip Masterson; Mark J O'Connor; Stephen P Jackson
hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
Cell 2005;123(6):1065-78.
2005: Anne C Harvey; Stephen P Jackson; Jessica Downs
Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair.
Genetics 2005;170(2):543-53.
2005: Jacob Falck; Julia Coates; Stephen P Jackson
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Nature 2005;434(7033):605-11.
2005: Sabrina Giavara; Effie Kosmidou; M Prakash Hande; Marco E Bianchi; Alan Morgan; Fabrizio d'Adda di Fagagna; Stephen P Jackson
Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability.
Current biology : CB 2005;15(1):68-72.
2004: Jessica Downs; Stéphane Allard; Olivier Jobin-Robitaille; Ali Javaheri; Andréanne Auger; Nathalie Bouchard; Stephen J Kron; Stephen P Jackson; Jacques Côté
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites.
Molecular cell 2004;16(6):979-90.
2004: Enriqueta Riballo; Martin Kühne; Nicole Rief; Aidan Doherty; Graeme C M Smith; María-José Recio; Caroline Reis; Dr. Kirsten Dahm; Andreas Fricke; Andrea Krempler; Antony R Parker; Stephen P Jackson; Andrew R Gennery; Penny A Jeggo; Markus Löbrich
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
Molecular cell 2004;16(5):715-24.
2004: Shoshana Squires; Julia A Coates; Michal Goldberg; Lorraine H Toji; Stephen P Jackson; Duncan J Clarke; robert johnson
p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells.
Cell cycle (Georgetown, Tex.) 2004;3(12):1543-57.
2004: Fabrizio d'Adda di Fagagna; Soo-Hwang Teo; Stephen P Jackson
Functional links between telomeres and proteins of the DNA-damage response.
Genes & development 2004;18(15):1781-99.
2004: Manuel Stucki; Stephen P Jackson
MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes.
DNA repair 2004;3(8-9):953-7.
2004: Claudia Lukas; Fredrik Melander; Manuel Stucki; Jacob Falck; Simon Bekker-Jensen; Michal Goldberg; Yaniv lerenthal; Stephen P Jackson; Jiri Bartek; Jiri Lukas
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.
The EMBO journal 2004;23(13):2674-83.
2004: Jessica Downs; Stephen P Jackson
A means to a DNA end: the many roles of Ku.
Nature reviews. Molecular cell biology 2004;5(5):367-78.
2004: Philip M Reaper; Fabrizio d'Adda di Fagagna; Stephen P Jackson
Activation of the DNA damage response by telomere attrition: a passage to cellular senescence.
Cell cycle (Georgetown, Tex.) 2004;3(5):543-6.
2004: Ali Jazayeri; Andrew D McAinsh; Stephen P Jackson
Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1644-9.
2004: Rajat Roy; Bettina Meier; Andrew D McAinsh; Heidi M Feldmann; Stephen P Jackson
Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing.
The Journal of biological chemistry 2004;279(1):86-94.
2003: Fabrizio d'Adda di Fagagna; Philip M Reaper; Lorena Clay-Farrace; Heike Fiegler; Philippa Carr; Thomas von Zglinicki; Gabriele Saretzki; Nigel P Carter; Stephen P Jackson
A DNA damage checkpoint response in telomere-initiated senescence.
Nature 2003;426(6963):194-8.
2003: Jane M Bradbury; Stephen P Jackson
ATM and ATR.
Current biology : CB 2003;13(12):R468.
2003: Jessica Downs; Effie Kosmidou; Alan Morgan; Stephen P Jackson
Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone.
Molecular cell 2003;11(6):1685-92.
2003: Michal Goldberg; Manuel Stucki; Jacob Falck; Damien D'Amours; Dinah Rahman; Darryl Pappin; Jiri Bartek; Stephen P Jackson
MDC1 is required for the intra-S-phase DNA damage checkpoint.
Nature 2003;421(6926):952-6.
2003: J M Bradbury; Stephen P Jackson
The complex matter of DNA double-strand break detection.
Biochemical Society transactions 2003;31(Pt 1):40-4.
2003: Fabrizio d'Adda di Fagagna; Geoffrey R Weller; Aidan J Doherty; Stephen P Jackson
The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku.
EMBO reports 2003;4(1):47-52.
2002: Geoffrey R Weller; Boris Kysela; Rajat Roy; Louise M Tonkin; Elizabeth Scanlan; Marina Della; Susanne Krogh Devine; Jonathan P Day; Adam Wilkinson; Fabrizio d'Adda di Fagagna; Kevin M Devine; Richard P Bowater; Penny A Jeggo; Stephen P Jackson; Aidan J Doherty
Identification of a DNA nonhomologous end-joining complex in bacteria.
Science (New York, N.Y.) 2002;297(5587):1686-9.
2002: John Rouse; Stephen P Jackson
Interfaces between the detection, signaling, and repair of DNA damage.
Science (New York, N.Y.) 2002;297(5581):547-51.
2002: Jiejin Li; Brandi L Williams; Lesley F Haire; Michal Goldberg; Erik W Wilker; Daniel Durocher; Michael B Yaffe; Stephen P Jackson; Stephen John Smerdon
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.
Molecular cell 2002;9(5):1045-54.
2002: Damien D'Amours; Stephen P Jackson
The Mre11 complex: at the crossroads of dna repair and checkpoint signalling.
Nature reviews. Molecular cell biology 2002;3(5):317-27.
2002: John Rouse; Stephen P Jackson
Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo.
Molecular cell 2002;9(4):857-69.
2002: Ali Jazayeri; Stephen P Jackson
Screening the yeast genome for new DNA-repair genes.
Genome biology 2002;3(4):REVIEWS1009.
2001: C P Magill; Stephen P Jackson; Steve Bell
Identification of a conserved archaeal RNA polymerase subunit contacted by the basal transcription factor TFB.
The Journal of biological chemistry 2001;276(50):46693-6.
2001: Bancinyane L Sibanda; S E Critchlow; J Begun; X Y Pei; Stephen P Jackson; Tom L Blundell; Luca Pellegrini
Crystal structure of an Xrcc4-DNA ligase IV complex.
Nature structural biology 2001;8(12):1015-9.
2001: Aidan J Doherty; Stephen P Jackson
DNA repair: how Ku makes ends meet.
Current biology : CB 2001;11(22):R920-4.
2001: Stephen P Jackson
Detecting, signalling and repairing DNA double-strand breaks.
Biochemical Society transactions 2001;29(Pt 6):655-61.
2001: Damien D'Amours; Stephen P Jackson
The yeast Xrs2 complex functions in S phase checkpoint regulation.
Genes & development 2001;15(17):2238-49.
2001: Fabrizio d'Adda di Fagagna; M P Hande; Wei-Min Tong; D Roth; P M Lansdorp; Z Q Wang; Stephen P Jackson
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.
Current biology : CB 2001;11(15):1192-6.
2001: Steve Bell; C P Magill; Stephen P Jackson
Basal and regulated transcription in Archaea.
Biochemical Society transactions 2001;29(Pt 4):392-5.
2001: Raimundo Freire; Fabrizio d'Adda di Fagagna; L Wu; Graziella Pedrazzi; Igor Stagljar; Ian D Hickson; Stephen P Jackson
Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha.
Nucleic acids research 2001;29(15):3172-80.
2001: Aidan J Doherty; Stephen P Jackson; Geoffrey R Weller
Identification of bacterial homologues of the Ku DNA repair proteins.
FEBS letters 2001;500(3):186-8.
2001: K Eichhorn; Stephen P Jackson
A role for TAF3B2 in the repression of human RNA polymerase III transcription in nonproliferating cells.
The Journal of biological chemistry 2001;276(24):21158-65.
2001: Steve Bell; Stephen P Jackson
Mechanism and regulation of transcription in archaea.
Current opinion in microbiology 2001;4(2):208-13.
2001: Daniel Durocher; Stephen P Jackson
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
Current opinion in cell biology 2001;13(2):225-31.
2001: SH Teo; Stephen P Jackson
Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant.
EMBO reports 2001;2(3):197-202.
2001: Steve Bell; Arie B Brinkman; John van der Oost; Stephen P Jackson
The archaeal TFIIEalpha homologue facilitates transcription initiation by enhancing TATA-box recognition.
EMBO reports 2001;2(2):133-8.
2000: Jessica Downs; N F Lowndes; Stephen P Jackson
A role for Saccharomyces cerevisiae histone H2A in DNA repair.
Nature 2000;408(6815):1001-4.
2000: Daniel Durocher; Ian A Taylor; Dilara Sarbassova; Lesley F Haire; S L Westcott; Stephen P Jackson; Stephen John Smerdon; Michael B Yaffe
The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
Molecular cell 2000;6(5):1169-82.
2000: J Rouse; Stephen P Jackson
LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae.
The EMBO journal 2000;19(21):5801-12.
2000: Steve Bell; Stephen P Jackson
Mechanism of autoregulation by an archaeal transcriptional repressor.
The Journal of biological chemistry 2000;275(41):31624-9.
2000: SH Teo; Stephen P Jackson
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
Current biology : CB 2000;10(3):165-8.
2000: Daniel Durocher; Stephen John Smerdon; Michael B Yaffe; Stephen P Jackson
The FHA domain in DNA repair and checkpoint signaling.
Cold Spring Harbor symposia on quantitative biology 2000;65():423-31.
1999: Steve Bell; S S Cairns; R L Robson; Stephen P Jackson
Transcriptional regulation of an archaeal operon in vivo and in vitro.
Molecular cell 1999;4(6):971-82.
1999: Steve Bell; P L Kosa; Paul B Sigler; Stephen P Jackson
Orientation of the transcription preinitiation complex in archaea.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13662-7.
1999: GC Smith; R B Cary; ND Lakin; B C Hann; S H Teo; D J Chen; Stephen P Jackson
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11134-9.
1999: Andrew D McAinsh; Suzanna R S Scott-Drew; James Murray; Stephen P Jackson
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p.
Current biology : CB 1999;9(17):963-6.
1999: D Durocher; julia hepp; Alan Fersht; Stephen P Jackson
The FHA domain is a modular phosphopeptide recognition motif.
Molecular cell 1999;4(3):387-94.
1999: Fabrizio d'Adda di Fagagna; M P Hande; Wei-Min Tong; P M Lansdorp; Z Q Wang; Stephen P Jackson
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.
Nature genetics 1999;23(1):76-80.
1999: Jessica Downs; Stephen P Jackson
Involvement of DNA end-binding protein Ku in Ty element retrotransposition.
Molecular and cellular biology 1999;19(9):6260-8.
1999: GC Smith; Fabrizio d'Adda di Fagagna; ND Lakin; Stephen P Jackson
Cleavage and inactivation of ATM during apoptosis.
Molecular and cellular biology 1999;19(9):6076-84.
1999: D Gell; Stephen P Jackson
Mapping of protein-protein interactions within the DNA-dependent protein kinase complex.
Nucleic acids research 1999;27(17):3494-502.
1999: ND Lakin; B C Hann; Stephen P Jackson
The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.
Oncogene 1999;18(27):3989-95.
1999: Enriqueta Riballo; S E Critchlow; S H Teo; Aidan J Doherty; A Priestley; Bernard C Broughton; Boris Kysela; Heather Beamish; N Plowman; Colin F Arlett; Alan Lehmann; Stephen P Jackson; Penny A Jeggo
Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient.
Current biology : CB 1999;9(13):699-702.
1999: Stephen P Jackson
Colworth Medal lecture. Detection, repair and signalling of DNA double-strand breaks.
Biochemical Society transactions 1999;27(2):1-13.
1999: GC Smith; Nullin Divecha; ND Lakin; Stephen P Jackson
DNA-dependent protein kinase and related proteins.
Biochemical Society symposium 1999;64():91-104.
1998: Steve Bell; C Jaxel; M Nadal; P F Kosa; Stephen P Jackson
Temperature, template topology, and factor requirements of archaeal transcription.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15218-22.
1998: Guillermo E Taccioli; A G Amatucci; Heather Beamish; D Gell; XH Xiang; MI Torres Arzayus; A Priestley; Stephen P Jackson; Ann Marshak-Rothstein; Penny A Jeggo; Victoria L M Herrera
Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity.
Immunity 1998;9(3):355-66.
1998: R Freire; J R Murguía; Madalena Tarsounas; N F Lowndes; Peter B Moens; Stephen P Jackson
Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.
Genes & development 1998;12(16):2560-73.
1998: U Yavuzer; GC Smith; T Bliss; D Werner; Stephen P Jackson
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D.
Genes & development 1998;12(14):2188-99.
1998: M Escarceller; M Buchwald; BK Singleton; Penny A Jeggo; Stephen P Jackson; Ethel Moustacchi; Dora Papadopoulo
Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining.
Journal of molecular biology 1998;279(2):375-85.
1998: Steve Bell; Stephen P Jackson
Transcription and translation in Archaea: a mosaic of eukaryal and bacterial features.
Trends in microbiology 1998;6(6):222-8.
1998: A Priestley; Heather Beamish; D Gell; A G Amatucci; M C Muhlmann-Diaz; BK Singleton; G C Smith; T Blunt; L C Schalkwyk; Joel S Bedford; Stephen P Jackson; Penny A Jeggo; Guillermo E Taccioli
Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20.
Nucleic acids research 1998;26(8):1965-73.
1998: S J Boulton; Stephen P Jackson
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing.
The EMBO journal 1998;17(6):1819-28.
1998: Steve Bell; Stephen P Jackson
Transcription in Archaea.
Cold Spring Harbor symposia on quantitative biology 1998;63():41-51.
1997: SH Teo; Stephen P Jackson
Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair.
The EMBO journal 1997;16(15):4788-95.
1997: Stephen P Jackson
DNA-dependent protein kinase.
The international journal of biochemistry & cell biology 1997;29(7):935-8.
1997: S A Qureshi; Steve Bell; Stephen P Jackson
Factor requirements for transcription in the Archaeon Sulfolobus shibatae.
The EMBO journal 1997;16(10):2927-36.
1997: BK Singleton; A Priestley; H Steingrimsdottir; D Gell; T Blunt; Stephen P Jackson; Alan Lehmann; Penny A Jeggo
Molecular and biochemical characterization of xrs mutants defective in Ku80.
Molecular and cellular biology 1997;17(3):1264-73.
1996: ND Lakin; peter weber; T Stankovic; S T Rottinghaus; A M Taylor; Stephen P Jackson
Analysis of the ATM protein in wild-type and ataxia telangiectasia cells.
Oncogene 1996;13(12):2707-16.
1996: S J Boulton; Stephen P Jackson
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance.
Nucleic acids research 1996;24(23):4639-48.
1996: T Blunt; D Gell; M Fox; Guillermo E Taccioli; Alan Lehmann; Stephen P Jackson; Penny A Jeggo
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10285-90.
1996: R J White; D Trouche; K Martin; Stephen P Jackson; Tony Kouzarides
Repression of RNA polymerase III transcription by the retinoblastoma protein.
Nature 1996;382(6586):88-90.
1996: N J Finnie; Tanya Gottlieb; T Blunt; Penny A Jeggo; Stephen P Jackson
DNA-dependent protein kinase defects are linked to deficiencies in DNA repair and V(D)J recombination.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1336):173-9.
1996: Penny A Jeggo; Stephen P Jackson; Guillermo E Taccioli
Identification of the catalytic subunit of DNA dependent protein kinase as the product of the mouse scid gene.
Current topics in microbiology and immunology 1996;217():79-89.
1995: R J White; Tanya Gottlieb; C Stephen Downes; Stephen P Jackson
Cell cycle regulation of RNA polymerase III transcription.
Molecular and cellular biology 1995;15(12):6653-62.
1995: T Blunt; Guillermo E Taccioli; A Priestley; M Hafezparast; T McMillan; J Liu; C C Cole; J White; F W Alt; Stephen P Jackson
A YAC contig encompassing the XRCC5 (Ku80) DNA repair gene and complementation of defective cells by YAC protoplast fusion.
Genomics 1995;30(2):320-8.
1995: Penny A Jeggo; Guillermo E Taccioli; Stephen P Jackson
Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(11):949-57.
1995: K O Hartley; D Gell; GC Smith; H Zhang; Nullin Divecha; M A Connelly; A Admon; Susan Lees-Miller; C W Anderson; Stephen P Jackson
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product.
Cell 1995;82(5):849-56.
1995: R J White; Tanya Gottlieb; C Stephen Downes; Stephen P Jackson
Mitotic regulation of a TATA-binding-protein-containing complex.
Molecular and cellular biology 1995;15(4):1983-92.
1995: N J Finnie; Tanya Gottlieb; T Blunt; Penny A Jeggo; Stephen P Jackson
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):320-4.
1994: R J White; B C Khoo; J A Inostroza; D Reinberg; Stephen P Jackson
Differential regulation of RNA polymerases I, II, and III by the TBP-binding repressor Dr1.
Science (New York, N.Y.) 1994;266(5184):448-50.
1994: Guillermo E Taccioli; Tanya Gottlieb; T Blunt; A Priestley; Jocelyne Demengeot; R Mizuta; Alan Lehmann; F W Alt; Stephen P Jackson; Penny A Jeggo
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination.
Science (New York, N.Y.) 1994;265(5177):1442-5.
1993: N Finnie; T Gottlieb; K Hartley; Stephen P Jackson
Transcription factor phosphorylation by the DNA-dependent protein kinase.
Biochemical Society transactions 1993;21(4):930-5.