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Christian Jacob

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Disorders

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S Heinzel; Christian P Jacob; Klaus-Peter Lesch; Andreas Reif; Tobias Renner; CG Baehne; Andrea Boreatti-Hümmer; Thomas Dresler; Andreas J Fallgatter; Monika Heine; Ann-Christine Ehlis
COMT x DRD4 Epistasis Impacts Prefrontal Cortex Function Underlying Response Control.
Andreas Reif; Andreas Ströhle; Heike Weber; Hans-Ulrich Wittchen; Georg W Alpers; Volker Arolt; Christian Baumann; Elisabeth B Binder; Katharina Domschke; Angelika Erhardt; Alexander L Gerlach; Alfons Hamm; Christian P Jacob; Tilo Kircher; Benedikt Klauke; Paul Pauli; Jürgen Deckert
Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations.
Marta Ribasés; Cristina Sánchez-Mora; Rosa Bosch; Miquel Casas; Bru Cormand; Montse Corrales; Núria Gómez; Silke Gross-Lesch; Christian P Jacob; Susanne Kreiker; Klaus Peter Lesch; Mariana Nogueira; Gloria Palomar; Josep Antoni Ramos-Quiroga; Andreas Reif; Mónica Bayés
An association study of sequence variants in the forkhead box P2 (FOXP2) gene and adulthood attention-deficit/hyperactivity disorder in two European samples.

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All Publications

2013: S Heinzel; Christian P Jacob; Klaus-Peter Lesch; Andreas Reif; Tobias Renner; CG Baehne; Andrea Boreatti-Hümmer; Thomas Dresler; Andreas J Fallgatter; Monika Heine; Ann-Christine Ehlis
COMT x DRD4 Epistasis Impacts Prefrontal Cortex Function Underlying Response Control.
Cerebral cortex (New York, N.Y. : 1991) 2013;23(6):1453-62.
2012: Andreas Reif; Andreas Ströhle; Heike Weber; Hans-Ulrich Wittchen; Georg W Alpers; Volker Arolt; Christian Baumann; Elisabeth B Binder; Katharina Domschke; Angelika Erhardt; Alexander L Gerlach; Alfons Hamm; Christian P Jacob; Tilo Kircher; Benedikt Klauke; Paul Pauli; Jürgen Deckert
Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2012;159B(7):786-93.
2012: Marta Ribasés; Cristina Sánchez-Mora; Rosa Bosch; Miquel Casas; Bru Cormand; Montse Corrales; Núria Gómez; Silke Gross-Lesch; Christian P Jacob; Susanne Kreiker; Klaus Peter Lesch; Mariana Nogueira; Gloria Palomar; Josep Antoni Ramos-Quiroga; Andreas Reif; Mónica Bayés
An association study of sequence variants in the forkhead box P2 (FOXP2) gene and adulthood attention-deficit/hyperactivity disorder in two European samples.
Psychiatric genetics 2012;22(4):155-60.
2012: Edna Grünblatt; Christian P Jacob; Klaus-Peter Lesch; Maja Müller; Tobias Renner; Peter Riederer; Jasmin Bartl; Julia Geissler; Manfred Gerlach; Silke Gross-Lesch; Susanne Walitza; Angelika Schmitt
Pilot study: potential transcription markers for adult attention-deficit hyperactivity disorder in whole blood.
Attention deficit and hyperactivity disorders 2012;4(2):77-84.
2012: Heike Weber; Hans-Ulrich Wittchen; Peter Michael Zwanzger; Claus Jürgen Scholz; Andreas Ströhle; Georg W Alpers; Volker Arolt; Borwin Bandelow; Christian Baumann; Jürgen Deckert; Katharina Domschke; Lydia Fehm; Jürgen Fritze; Alexander L Gerlach; Alfons Hamm; Christian P Jacob; Tilo Kircher; Benedikt Klauke; Thomas Lang; Wolfgang Maier; Paul Pauli; Andreas Reif
Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder.
PloS one 2012;7(5):e37651.
2011: Heike Weber; Lena Weissflog; Julia Volkert; Volker Arolt; Bernhard T Baune; Andrea Boreatti-Hümmer; Henriette N Buttenschon; Jürgen Deckert; Katharina Domschke; Alexandra Gessner; Silke Gross-Lesch; Sabine Herterich; Christian P Jacob; Sarah Kittel-Schneider; Juliane Kopf; Susanne Kreiker; Klaus-Peter Lesch; Ole Mors; Maria Neuner; Thuy Trang Nguyen; Andreas Reif
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(10):2076-85.
2011: Andreas Reif; Martin Schecklmann; Elisa Eirich; Andreas J Fallgatter; Christian P Jacob; Tomasz A Jarczok; Sarah Kittel-Schneider; Klaus-Peter Lesch; Ann-Christine Ehlis
A functional promoter polymorphism of neuronal nitric oxide synthase moderates prefrontal functioning in schizophrenia.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(7):887-97.
2011: Cristina Sánchez-Mora; Phil Asherson; Mònica Bayés; Rosa Bosch; Lucas Brunso; Jan K Buitelaar; Miguel Casas; Stephen V Faraone; Noelia Fernàndez-Castillo; Barbara Franke; Silke Gross-Lesch; Jan Haavik; Martine Hoogman; Christian P Jacob; Kaya K Jacobsen; Stefan Johansson; Lambertus A L M Kiemeney; J J Sandra Kooij; Susanne Kreiker; Elisabeth T Landaas; Klaus-Peter Lesch; Astri J Lundervold; Eric Mick; Josep Antoni Ramos-Quiroga; Andreas Reif; Marta Ribasés; Bru Cormand
Exploring DRD4 and its interaction with SLC6A3 as possible risk factors for adult ADHD: a meta-analysis in four European populations.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(5):600-12.
2011: Annette Conzelmann; Eva Woidich; Ronald F Mucha; Peter Weyers; Christian P Jacob; Klaus-Peter Lesch; Paul Pauli
Methylphenidate normalizes emotional processing in adult patients with attention-deficit/hyperactivity disorder: preliminary findings.
Brain research 2011;1381():159-66.
2010: Edna Grünblatt; Sonja Zehetmayer; Christian P Jacob; Thomas Müller; Wolfgang H Jost; Peter Riederer
Pilot study: peripheral biomarkers for diagnosing sporadic Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(12):1387-93.
2010: Thomas Dresler; Ann-Christine Ehlis; Sebastian Heinzel; Tobias J Renner; Andreas Reif; CG Baehne; Monika Heine; Andrea Boreatti-Hümmer; Christian P Jacob; Klaus-Peter Lesch; Andreas J Fallgatter
Dopamine transporter (SLC6A3) genotype impacts neurophysiological correlates of cognitive response control in an adult sample of patients with ADHD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(11):2193-202.
2010: Annette Conzelmann; Paul Pauli; Ronald F Mucha; Christian P Jacob; Antje B M Gerdes; Jasmin Romanos; Christina G Bähne; Monika Heine; Andrea Boreatti-Hümmer; Georg W Alpers; Andreas J Fallgatter; Andreas Warnke; Klaus-Peter Lesch; Peter Weyers
Early attentional deficits in an attention-to-prepulse paradigm in ADHD adults.
Journal of abnormal psychology 2010;119(3):594-603.
2010: E T Landaas; Stefan Johansson; K K Jacobsen; Marta Ribasés; R Bosch; C Sánchez-Mora; Christian P Jacob; A Boreatti-Hümmer; S Kreiker; K-P Lesch; L A Kiemeney; J J Sandra Kooij; C Kan; Jan K Buitelaar; S V Faraone; A Halmøy; Josep Antoni Ramos-Quiroga; B Cormand; A Reif; Barbara Franke; E Mick; Per M Knappskog; Jan Haavik
An international multicenter association study of the serotonin transporter gene in persistent ADHD.
Genes, brain, and behavior 2010;9(5):449-58.
2010: Claus-Jürgen Scholz; Christian P Jacob; Henriette N Buttenschon; Sarah Kittel-Schneider; Andrea Boreatti-Hümmer; Michael Zimmer; Ulrich Walter; Klaus-Peter Lesch; Ole Mors; Susanne Kneitz; Jürgen Deckert; Andreas Reif
Functional variants of TSPAN8 are associated with bipolar disorder and schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(4):967-72.
2010: Christian P Jacob; Thuy Trang Nguyen; Astrid Dempfle; Monika Heine; Christine Windemuth-Kieselbach; Katarina Baumann; Florian Jacob; Julian Prechtl; Maike Wittlich; Martin J Herrmann; Silke Gross-Lesch; Klaus-Peter Lesch; Andreas Reif
A gene-environment investigation on personality traits in two independent clinical sets of adult patients with personality disorder and attention deficit/hyperactive disorder.
European archives of psychiatry and clinical neuroscience 2010;260(4):317-26.
2010: C Sánchez-Mora; Marta Ribasés; Josep Antoni Ramos-Quiroga; Miguel Casas; R Bosch; A Boreatti-Hümmer; M Heine; Christian P Jacob; K-P Lesch; O B Fasmer; Per M Knappskog; J J Sandra Kooij; C Kan; Jan K Buitelaar; E Mick; P Asherson; S V Faraone; Barbara Franke; S Johansson; J Haavik; A Reif; M Bayés; Bru Cormand
Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(2):512-23.
2010: Paul Pauli; Annette Conzelmann; Ronald F Mucha; Peter Weyers; CG Baehne; Andreas J Fallgatter; Christian P Jacob; Klaus Peter Lesch
Affect-modulated startle reflex and dopamine D4 receptor gene variation.
Psychophysiology 2010;47(1):25-33.
2009: Andreas J Fallgatter; Christian P Jacob
[Comorbidity of substance use disorders and attention-deficit hyperactivity disorders: pathogenesis and therapy].
Der Nervenarzt 2009;80(9):1015-21.
2009: Martin J Herrmann; Heidi Würflein; Theresa Schreppel; Saskia Koehler; Andreas Mühlberger; Andreas Reif; Turhan Canli; Marcel Romanos; Christian P Jacob; Klaus-Peter Lesch; Andreas J Fallgatter
Catechol-O-methyltransferase Val158Met genotype affects neural correlates of aversive stimuli processing.
Cognitive, affective & behavioral neuroscience 2009;9(2):168-72.
2009: Annette Conzelmann; Ronald F Mucha; Christian P Jacob; Peter Weyers; Jasmin Romanos; Antje B M Gerdes; CG Baehne; Andrea Boreatti-Hümmer; Monika Heine; Georg W Alpers; Andreas Warnke; Andreas J Fallgatter; Klaus-Peter Lesch; Paul Pauli
Abnormal affective responsiveness in attention-deficit/hyperactivity disorder: subtype differences.
Biological psychiatry 2009;65(7):578-85.
2009: C Hess; Andreas Reif; Alexander Strobel; A Boreatti-Hümmer; M Heine; Klaus-Peter Lesch; Christian P Jacob
A functional dopamine-beta-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(2):121-30.
2009: Edna Grünblatt; Jasmin Bartl; Sonja Zehetmayer; Thomas M Ringel; Peter Bauer; Peter Riederer; Christian P Jacob
Gene expression as peripheral biomarkers for sporadic Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(3):627-34.
2009: Andreas Reif; Christian P Jacob; Dan Rujescu; Sabine Herterich; Sebastian Lang; Lise Gutknecht; CG Baehne; Alexander Strobel; Christine M Freitag; Ina Giegling; Marcel Romanos; Annette Hartmann; Michael Rösler; Tobias J Renner; Andreas J Fallgatter; Wolfgang Retz; Ann-Christine Ehlis; Klaus-Peter Lesch
Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans.
Archives of general psychiatry 2009;66(1):41-50.
2008: Ann-Christine Ehlis; Christina G Bähne; Christian P Jacob; Martin J Herrmann; Andreas J Fallgatter
Reduced lateral prefrontal activation in adult patients with attention-deficit/hyperactivity disorder (ADHD) during a working memory task: a functional near-infrared spectroscopy (fNIRS) study.
Journal of psychiatric research 2008;42(13):1060-7.
2008: Christian P Jacob; A Philipsen; D Ebert; Jürgen Deckert
[Multimodal treatment of adult attention-deficit hyperactivity disorder].
Der Nervenarzt 2008;79(7):801-8.
2007: Andreas Reif; Michael Rösler; Christine M Freitag; Marc Schneider; Andrea Eujen; Christian Kissling; Denise Wenzler; Christian P Jacob; Petra Retz-Junginger; Johannes Thome; Klaus-Peter Lesch; Wolfgang Retz
Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(11):2375-83.
2007: Christian P Jacob; Jasmin Romanos; Astrid Dempfle; Monika Heine; Christine Windemuth-Kieselbach; Anja Kruse; Andreas Reif; Susanne Walitza; Marcel Romanos; Alexander Strobel; Burkhard Brocke; Helmut Schäfer; Armin Schmidtke; Jobst Böning; Klaus-Peter Lesch
Co-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral center.
European archives of psychiatry and clinical neuroscience 2007;257(6):309-17.
2007: Melany M Richter; Ann-Christine Ehlis; Christian P Jacob; Andreas J Fallgatter
Cortical excitability in adult patients with attention-deficit/hyperactivity disorder (ADHD).
Neuroscience letters 2007;419(2):137-41.
2007: Sandra Selch; Alexander Strobel; Julia Haderlein; Jobst Meyer; Christian P Jacob; Angelika Schmitt; Klaus-Peter Lesch; Andreas Reif
MLC1 polymorphisms are specifically associated with periodic catatonia, a subgroup of chronic schizophrenia.
Biological psychiatry 2007;61(10):1211-4.
2007: Christian P Jacob; Eleni Koutsilieri; J Bartl; Eva Neuen-Jacob; Thomas Arzberger; N Zander; Rivka Ravid; Wolfgang Roggendorf; Peter Riederer; Edna Grünblatt
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(1):97-116.
2007: Andreas Reif; M Melchers; Alexander Strobel; Christian P Jacob; Sabine Herterich; Klaus-Peter Lesch; M Zimmer
FZD3 is not a risk gene for schizophrenia: a case-control study in a Caucasian sample.
Journal of neural transmission. Supplementum 2007;(72):297-301.
2006: Burkhard Brocke; D Armbruster; J Muller; Tilman Hensch; Christian P Jacob; Klaus-Peter Lesch; C Kirschbaum; Alexander Strobel
Serotonin transporter gene variation impacts innate fear processing: Acoustic startle response and emotional startle.
Molecular psychiatry 2006;11(12):1106-12.
2006: Andreas Reif; Sabine Herterich; Alexander Strobel; Ann-Christine Ehlis; D Saur; Christian P Jacob; Thomas F Wienker; Theresia Töpner; Sabrina Fritzen; Ulrich Walter; Angelika Schmitt; Andreas J Fallgatter; Klaus-Peter Lesch
A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function.
Molecular psychiatry 2006;11(3):286-300.
2006: Andreas Reif; Alexander Strobel; Christian P Jacob; Sabine Herterich; Christine M Freitag; Theresia Töpner; Rainald Mössner; Sabrina Fritzen; Angelika Schmitt; Klaus-Peter Lesch
A NOS-III haplotype that includes functional polymorphisms is associated with bipolar disorder.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2006;9(1):13-20.
2005: Christian P Jacob; Johannes Müller; Michael Schmidt; Katrin Hohenberger; Lise Gutknecht; Andreas Reif; Armin Schmidtke; Rainald Mössner; Klaus-Peter Lesch
Cluster B personality disorders are associated with allelic variation of monoamine oxidase A activity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(9):1711-8.
2005: Martin J Herrmann; Ann-Christine Ehlis; Annika Wagener; Christian P Jacob; Andreas J Fallgatter
Near-infrared optical topography to assess activation of the parietal cortex during a visuo-spatial task.
Neuropsychologia 2005;43(12):1713-20.
2004: Thomas M Ringel; Anke Heidrich; Christian P Jacob; Bruno Pfuhlmann; Gerald Stoeber; Andreas J Fallgatter
Sensory gating deficit in a subtype of chronic schizophrenic patients.
Psychiatry research 2004;125(3):237-45.
2004: Christian P Jacob; Alexander Strobel; Katrin Hohenberger; Thomas M Ringel; Lise Gutknecht; Andreas Reif; Burkhard Brocke; Klaus-Peter Lesch
Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster C personality disorders.
The American journal of psychiatry 2004;161(3):569-72.