Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Sten Eirik Jacobsen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Living Beings

Physiology

Chemicals & Drugs

Concepts & Ideas

Cell Lineage

Procedures

Hematopoietic Stem Cell Transplantation

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Bereshchenko Oxana; Mancini Elena; Moore Susan; Bilbao Daniel; Månsson Robert; Luc Sidinh; Grover Amit; Jacobsen Sten Eirik W; Bryder David; Nerlov Claus
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.
Bröske Ann-Marie; Vockentanz Lena; Kharazi Shabnam; Huska Matthew R; Mancini Elena; Scheller Marina; Kuhl Christiane; Enns Andreas; Prinz Marco; Jaenisch Rudolf; Nerlov Claus; Leutz Achim; Andrade-Navarro Miguel A; Jacobsen Sten Eirik W; Rosenbauer Frank
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Enver Tariq; Jacobsen Sten Eirik W
Developmental biology: Instructions writ in blood.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Sten Eirik Jacobsen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Bereshchenko Oxana; Mancini Elena; Moore Susan; Bilbao Daniel; Månsson Robert; Luc Sidinh; Grover Amit; Jacobsen Sten Eirik W; Bryder David; Nerlov Claus
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.
Cancer cell 2009;16(5):390-400.
2009: Bröske Ann-Marie; Vockentanz Lena; Kharazi Shabnam; Huska Matthew R; Mancini Elena; Scheller Marina; Kuhl Christiane; Enns Andreas; Prinz Marco; Jaenisch Rudolf; Nerlov Claus; Leutz Achim; Andrade-Navarro Miguel A; Jacobsen Sten Eirik W; Rosenbauer Frank
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Nature genetics 2009;41(11):1207-15.
2009: Enver Tariq; Jacobsen Sten Eirik W
Developmental biology: Instructions writ in blood.
Nature 2009;461(7261):183-4.
2009: Thored Pär; Heldmann Ursula; Gomes-Leal Walace; Gisler Ramiro; Darsalia Vladimer; Taneera Jalal; Nygren Jens M; Jacobsen Sten-Eirik W; Ekdahl Christine T; Kokaia Zaal; Lindvall Olle
Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.
Glia 2009;57(8):835-49.
2009: Liuba Karina; Pronk Cornelis J H; Stott Simon R W; Jacobsen Sten-Eirik W
Polyclonal T-cell reconstitution of X-SCID recipients after in utero transplantation of lymphoid-primed multipotent progenitors.
Blood 2009;113(19):4790-8.
2009: Buza-Vidas Natalija; Cheng Min; Duarte Sara; Charoudeh Hojjatollah Nozad; Jacobsen Sten Eirik W; Sitnicka Ewa
FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.
Blood 2009;113(15):3453-60.
2009: Tipping Alex J; Pina Cristina; Castor Anders; Hong Dengli; Rodrigues Neil P; Lazzari Lorenza; May Gillian E; Jacobsen Sten Eirik W; Enver Tariq
High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle.
Blood 2009;113(12):2661-72.
2009: Cheng Min; Charoudeh Hojjatollah Nozad; Brodin Petter; Tang Yanjuan; Lakshmikanth Tadepally; Höglund Petter; Jacobsen Sten Eirik W; Sitnicka Ewa
Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(3):1460-8.
2008: Jensen Christina T; Kharazi Shabnam; Böiers Charlotta; Cheng Min; Lübking Anna; Sitnicka Ewa; Jacobsen Sten Eirik W
FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis.
Blood 2008;112(6):2297-304.
2008: Luc Sidinh; Buza-Vidas Natalija; Jacobsen Sten Eirik W
Delineating the cellular pathways of hematopoietic lineage commitment.
Seminars in immunology 2008;20(4):213-20.
2008: Mansson Robert; Zandi Sasan; Anderson Kristina; Martensson Inga-Lill; Jacobsen Sten Eirik W; Bryder David; Sigvardsson Mikael
B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells.
Blood 2008;112(4):1048-55.
2008: Weischenfeldt Joachim; Damgaard Inge; Bryder David; Theilgaard-Mönch Kim; Thoren Lina A; Nielsen Finn Cilius; Jacobsen Sten Eirik W; Nerlov Claus; Porse Bo Torben
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Genes & development 2008;22(10):1381-96.
2008: Nygren Jens M; Liuba Karina; Breitbach Martin; Stott Simon; Thorén Lina; Roell Wilhelm; Geisen Caroline; Sasse Philipp; Kirik Deniz; Björklund Anders; Nerlov Claus; Fleischmann Bernd K; Jovinge Stefan; Jacobsen Sten Eirik W
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
Nature cell biology 2008;10(5):584-92.
2008: Kirstetter Peggy; Schuster Mikkel B; Bereshchenko Oksana; Moore Susan; Dvinge Heidi; Kurz Elke; Theilgaard-Mönch Kim; Månsson Robert; Pedersen Thomas A; Pabst Thomas; Schrock Evelin; Porse Bo T; Jacobsen Sten Eirik W; Bertone Paul; Tenen Daniel G; Nerlov Claus
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Cancer cell 2008;13(4):299-310.
2008: Luc Sidinh; Anderson Kristina; Kharazi Shabnam; Buza-Vidas Natalija; Böiers Charlotta; Jensen Christina T; Ma Zhi; Wittmann Lilian; Jacobsen Sten Eirik W
Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.
Blood 2008;111(7):3424-34.
2008: Thorén Lina A; Liuba Karina; Bryder David; Nygren Jens M; Jensen Christina T; Qian Hong; Antonchuk Jennifer; Jacobsen Sten-Eirik W
Kit regulates maintenance of quiescent hematopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2045-53.
2008: Jensen Christina T; Böiers Charlotta; Kharazi Shabnam; Lübking Anna; Rydén Tobias; Sigvardsson Mikael; Sitnicka Ewa; Jacobsen Sten Eirik W
Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development.
Blood 2008;111(4):2083-90.
2008: Svensson Marcus; Marsal Jan; Uronen-Hansson Heli; Cheng Min; Jenkinson William; Cilio Corrado; Jacobsen Sten Eirik W; Sitnicka Ewa; Anderson Graham; Agace William W
Involvement of CCR9 at multiple stages of adult T lymphopoiesis.
Journal of leukocyte biology 2008;83(1):156-64.
2008: Buitenhuis Miranda; Verhagen Liesbeth P; van Deutekom Hanneke W M; Castor Anders; Verploegen Sandra; Koenderman Leo; Jacobsen Sten-Eirik W; Coffer Paul J
Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis.
Blood 2008;111(1):112-21.
2008: Hansson Frida; Toporski Jacek; Månsson Robert; Johansson Bertil; Norén-Nyström Ulrika; Jacobsen Sten Eirik W; Wiebe Thomas; Larsson Marcus; Sigvardsson Mikael; Castor Anders
Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression.
Molecular cancer 2008;7():67.
2007: Qian Hong; Buza-Vidas Natalija; Hyland Craig D; Jensen Christina T; Antonchuk Jennifer; Månsson Robert; Thoren Lina A; Ekblom Marja; Alexander Warren S; Jacobsen Sten Eirik W
Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells.
Cell stem cell 2007;1(6):671-84.
2007: Grövdal Michael; Khan Rasheed; Aggerholm Anni; Antunovic Petar; Astermark Jan; Bernell Per; Engström Lena-Maria; Kjeldsen Lars; Linder Olle; Nilsson Lars; Olsson Anna; Wallvik Jonas; Tangen Jon Magnus; Oberg Gunnar; Jacobsen Sten Eirik; Hokland Peter; Porwit Anna; Hellström-Lindberg Eva
Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7107-12.
2007: Lee Benjamin H; Tothova Zuzana; Levine Ross L; Anderson Kristina; Buza-Vidas Natalija; Cullen Dana E; McDowell Elizabeth P; Adelsperger Jennifer; Fröhling Stefan; Huntly Brian J P; Beran Miloslav; Jacobsen Sten Eirik; Gilliland D Gary
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.
Cancer cell 2007;12(4):367-80.
2007: Nilsson Lars; Edén Patrik; Olsson Eleonor; Månsson Robert; Astrand-Grundström Ingbritt; Strömbeck Bodil; Theilgaard-Mönch Kim; Anderson Kristina; Hast Robert; Hellström-Lindberg Eva; Samuelsson Jan; Bergh Gösta; Nerlov Claus; Johansson Bertil; Sigvardsson Mikael; Borg Ake; Jacobsen Sten Eirik W
The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.
Blood 2007;110(8):3005-14.
2007: Qian Hong; Georges-Labouesse Elisabeth; Nyström Alexander; Domogatskaya Anna; Tryggvason Karl; Jacobsen Sten Eirik W; Ekblom Marja
Distinct roles of integrins alpha6 and alpha4 in homing of fetal liver hematopoietic stem and progenitor cells.
Blood 2007;110(7):2399-407.
2007: Sitnicka Ewa; Buza-Vidas Natalija; Ahlenius Henrik; Cilio Corrado M; Gekas Christos; Nygren Jens M; Månsson Robert; Cheng Min; Jensen Christina T; Svensson Marcus; Leandersson Karin; Agace William W; Sigvardsson Mikael; Jacobsen Sten Eirik W
Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors.
Blood 2007;110(8):2955-64.
2007: Jensen Christina T; Kharazi Shabnam; Böiers Charlotta; Liuba Karina; Jacobsen Sten Eirik W
TSLP-mediated fetal B lymphopoiesis?
Nature immunology 2007;8(9):897; author reply 898.
2007: Breitbach Martin; Bostani Toktam; Roell Wilhelm; Xia Ying; Dewald Oliver; Nygren Jens M; Fries Jochen W U; Tiemann Klaus; Bohlen Heribert; Hescheler Juergen; Welz Armin; Bloch Wilhelm; Jacobsen Sten Eirik W; Fleischmann Bernd K
Potential risks of bone marrow cell transplantation into infarcted hearts.
Blood 2007;110(4):1362-9.
2007: Buza-Vidas Natalija; Luc Sidinh; Jacobsen Sten Eirik W
Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges.
Current opinion in hematology 2007;14(4):315-21.
2007: Buza-Vidas Natalija; Cheng Min; Duarte Sara; Nozad Hojjatollah; Jacobsen Sten Eirik W; Sitnicka Ewa
Crucial role of FLT3 ligand in immune reconstitution after bone marrow transplantation and high-dose chemotherapy.
Blood 2007;110(1):424-32.
2007: Pfenninger Cosima V; Roschupkina Teona; Hertwig Falk; Kottwitz Denise; Englund Elisabet; Bengzon Johan; Jacobsen Sten Eirik; Nuber Ulrike A
CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells.
Cancer research 2007;67(12):5727-36.
2007: Luc Sidinh; Buza-Vidas Natalija; Jacobsen Sten Eirik W
Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors.
Annals of the New York Academy of Sciences 2007;1106():89-94.
2007: Anderson Kristina; Rusterholz Corinne; Månsson Robert; Jensen Christina T; Bacos Karl; Zandi Sasan; Sasaki Yutaka; Nerlov Claus; Sigvardsson Mikael; Jacobsen Sten Eirik W
Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.
Blood 2007;109(9):3697-705.
2007: Månsson Robert; Hultquist Anne; Luc Sidinh; Yang Liping; Anderson Kristina; Kharazi Shabnam; Al-Hashmi Suleiman; Liuba Karina; Thorén Lina; Adolfsson Jörgen; Buza-Vidas Natalija; Qian Hong; Soneji Shamit; Enver Tariq; Sigvardsson Mikael; Jacobsen Sten Eirik W
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.
Immunity 2007;26(4):407-19.
2006: Kolossov Eugen; Bostani Toktam; Roell Wilhelm; Breitbach Martin; Pillekamp Frank; Nygren Jens M; Sasse Philipp; Rubenchik Olga; Fries Jochen W U; Wenzel Daniela; Geisen Caroline; Xia Ying; Lu Zhongju; Duan Yaqi; Kettenhofen Ralf; Jovinge Stefan; Bloch Wilhelm; Bohlen Heribert; Welz Armin; Hescheler Juergen; Jacobsen Sten Eirik; Fleischmann Bernd K
Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium.
The Journal of experimental medicine 2006;203(10):2315-27.
2006: Kirstetter Peggy; Anderson Kristina; Porse Bo T; Jacobsen Sten Eirik W; Nerlov Claus
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
Nature immunology 2006;7(10):1048-56.
2006: Iosif Robert E; Ekdahl Christine T; Ahlenius Henrik; Pronk Cornelis J H; Bonde Sara; Kokaia Zaal; Jacobsen Sten-Eirik W; Lindvall Olle
Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(38):9703-12.
2006: Buza-Vidas Natalija; Antonchuk Jennifer; Qian Hong; Månsson Robert; Luc Sidinh; Zandi Sasan; Anderson Kristina; Takaki Satoshi; Nygren Jens M; Jensen Christina T; Jacobsen Sten Eirik W
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.
Genes & development 2006;20(15):2018-23.
2006: Nygren Jens M; Bryder David; Jacobsen Sten Eirik W
Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):201-8.
2006: Roybon Laurent; Ma Zhi; Asztely Fredrik; Fosum Anna; Jacobsen Sten Eirik W; Brundin Patrik; Li Jia-Yi
Failure of transdifferentiation of adult hematopoietic stem cells into neurons.
Stem cells (Dayton, Ohio) 2006;24(6):1594-604.
2006: Qian Hong; Tryggvason Karl; Jacobsen Sten Eirik; Ekblom Marja
Contribution of alpha6 integrins to hematopoietic stem and progenitor cell homing to bone marrow and collaboration with alpha4 integrins.
Blood 2006;107(9):3503-10.
2006: Taneera Jalal; Rosengren Anders; Renstrom Erik; Nygren Jens M; Serup Palle; Rorsman Patrik; Jacobsen Sten Eirik W
Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate.
Diabetes 2006;55(2):290-6.
2005: Porse Bo T; Bryder David; Theilgaard-Mönch Kim; Hasemann Marie S; Anderson Kristina; Damgaard Inge; Jacobsen Sten Eirik W; Nerlov Claus
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.
The Journal of experimental medicine 2005;202(1):85-96.
2005: Castor Anders; Nilsson Lars; Astrand-Grundström Ingbritt; Buitenhuis Miranda; Ramirez Carole; Anderson Kristina; Strömbeck Bodil; Garwicz Stanislaw; Békássy Albert N; Schmiegelow Kjeld; Lausen Birgitte; Hokland Peter; Lehmann Sören; Juliusson Gunnar; Johansson Bertil; Jacobsen Sten Eirik W
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.
Nature medicine 2005;11(6):630-7.
2005: Buitenhuis Miranda; van Deutekom Hanneke W M; Verhagen Liesbeth P; Castor Anders; Jacobsen Sten Eirik W; Lammers Jan-Willem J; Koenderman Leo; Coffer Paul J
Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2.
Blood 2005;105(11):4272-81.
2005: Adolfsson Jörgen; Månsson Robert; Buza-Vidas Natalija; Hultquist Anne; Liuba Karina; Jensen Christina T; Bryder David; Yang Liping; Borge Ole-Johan; Thoren Lina A M; Anderson Kristina; Sitnicka Ewa; Sasaki Yutaka; Sigvardsson Mikael; Jacobsen Sten Eirik W
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.
Cell 2005;121(2):295-306.
2005: Yang Liping; Bryder David; Adolfsson Jörgen; Nygren Jens; Månsson Robert; Sigvardsson Mikael; Jacobsen Sten Eirik W
Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.
Blood 2005;105(7):2717-23.
2005: Jacobsen Sten Eirik W
Defining 'stemness': Notch and Wnt join forces?
Nature immunology 2005;6(3):234-6.
2005: Bryder David; Björgvinsdóttir Helga; Sasaki Yutaka; Jacobsen Sten Eirik W
Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion.
The journal of gene medicine 2005;7(2):137-44.
2005: Garwicz Daniel; Lennartsson Andreas; Jacobsen Sten Eirik W; Gullberg Urban; Lindmark Anders
Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.
Haematologica 2005;90(1):38-44.
2005: Yang Liping; Dybedal Ingunn; Bryder David; Nilsson Lars; Sitnicka Ewa; Sasaki Yutaka; Jacobsen Sten Eirik W
IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):752-7.
2004: Wang Lingwei; Jacobsen Sten Eirik W; Bengtsson Anders; Erlinge David
P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells.
BMC immunology 2004;5():16.
2004: Sasaki Yutaka; Jensen Christina T; Karlsson Stefan; Jacobsen Sten Eirik W
Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation.
Blood 2004;104(4):986-92.
2004: Nygren Jens M; Jovinge Stefan; Breitbach Martin; Säwén Petter; Röll Wilhelm; Hescheler Jürgen; Taneera Jalal; Fleischmann Bernd K; Jacobsen Sten Eirik W
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation.
Nature medicine 2004;10(5):494-501.
2004: Bryder David; Sasaki Yutaka; Borge Ole Johan; Jacobsen Sten-Eirik W
Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1548-52.
2003: Sitnicka Ewa; Brakebusch Cord; Martensson Inga-Lill; Svensson Marcus; Agace William W; Sigvardsson Mikael; Buza-Vidas Natalija; Bryder David; Cilio Corrado M; Ahlenius Henrik; Maraskovsky Eugene; Peschon Jacques J; Jacobsen Sten Eirik W
Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.
The Journal of experimental medicine 2003;198(10):1495-506.
2003: Sitnicka Ewa; Buza-Vidas Natalija; Larsson Staffan; Nygren Jens M; Liuba Karina; Jacobsen Sten Erik W
Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.
Blood 2003;102(3):881-6.
2003: Dybedal Ingunn; Yang Liping; Bryder David; Aastrand-Grundstrom Ingbritt; Leandersson Karin; Jacobsen Sten Eirik W
Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.
Blood 2003;102(1):118-26.
2003: Gu Yu-Chen; Kortesmaa Jarkko; Tryggvason Karl; Persson Jenny; Ekblom Peter; Jacobsen Sten-Eirik; Ekblom Marja
Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells.
Blood 2003;101(3):877-85.
2002: Sitnicka Ewa; Bryder David; Theilgaard-Mönch Kim; Buza-Vidas Natalija; Adolfsson Jörgen; Jacobsen Sten Eirik W
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.
Immunity 2002;17(4):463-72.
2002: Nilsson Lars; Astrand-Grundström Ingbritt; Anderson Kristina; Arvidsson Ingrid; Hokland Peter; Bryder David; Kjeldsen Lars; Johansson Bertil; Hellström-Lindberg Eva; Hast Robert; Jacobsen Sten Eirik W
Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.
Blood 2002;100(1):259-67.
2002: Björgvinsdóttir Helga; Bryder David; Sitnicka Ewa; Ramsfjell Veslemøy; De Jong Ineke; Olsson Karin; Rusterholz Corinne; Karlsson Stefan; Jacobsen Sten Eirik W
Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach.
Human gene therapy 2002;13(9):1061-73.
2002: Fan Xiaolong; Valdimarsdottir Gudrun; Larsson Jonas; Brun Ann; Magnusson Mattias; Jacobsen Sten Eirik; ten Dijke Peter; Karlsson Stefan
Transient disruption of autocrine TGF-beta signaling leads to enhanced survival and proliferation potential in single primitive human hemopoietic progenitor cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):755-62.
2001: Adolfsson J; Borge O J; Bryder D; Theilgaard-Mönch K; Astrand-Grundström I; Sitnicka E; Sasaki Y; Jacobsen S E
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity.
Immunity 2001;15(4):659-69.
2001: Bryder D; Ramsfjell V; Dybedal I; Theilgaard-Mönch K; Högerkorp C M; Adolfsson J; Borge O J; Jacobsen S E
Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.
The Journal of experimental medicine 2001;194(7):941-52.
2001: Dybedal I; Bryder D; Fossum A; Rusten L S; Jacobsen S E
Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells.
Blood 2001;98(6):1782-91.
2000: Mikkola H; Woods N B; Sjögren M; Helgadottir H; Hamaguchi I; Jacobsen S E; Trono D; Karlsson S
Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells.
Journal of virology 2000;74(24):11911-8.
2000: Woods N B; Fahlman C; Mikkola H; Hamaguchi I; Olsson K; Zufferey R; Jacobsen S E; Trono D; Karlsson S
Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells.
Blood 2000;96(12):3725-33.
2000: Nilsson L; Astrand-Grundström I; Arvidsson I; Jacobsson B; Hellström-Lindberg E; Hast R; Jacobsen S E
Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level.
Blood 2000;96(6):2012-21.
2000: Bryder D; Jacobsen S E
Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro.
Blood 2000;96(5):1748-55.
1999: Ramsfjell V; Bryder D; Björgvinsdóttir H; Kornfält S; Nilsson L; Borge O J; Jacobsen S E
Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells.
Blood 1999;94(12):4093-102.
1997: Veiby O P; Borge O J; Mârtensson A; Beck E X; Schade A E; Grzegorzewski K; Lyman S D; Mârtensson I L; Jacobsen S E
Bidirectional effect of interleukin-10 on early murine B-cell development: stimulation of flt3-ligand plus interleukin-7-dependent generation of CD19(-) ProB cells from uncommitted bone marrow progenitor cells and growth inhibition of CD19(+) ProB cells.
Blood 1997;90(11):4321-31.
1997: Dybedal I; Guan F; Borge O J; Veiby O P; Ramsfjell V; Nagata S; Jacobsen S E
Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells.
Blood 1997;90(9):3395-403.
1997: Borge O J; Ramsfjell V; Cui L; Jacobsen S E
Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34+CD38- bone marrow cells with multilineage potential at the single-cell level: key role of thrombopoietin.
Blood 1997;90(6):2282-92.
1997: Cui L; Ramsfjell V; Borge O J; Veiby O P; Lok S; Jacobsen S E
Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1961-9.
1997: Ramsfjell V; Borge O J; Cui L; Jacobsen S E
Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5169-77.
1996: Ramsfjell V; Borge O J; Veiby O P; Cardier J; Murphy M J; Lyman S D; Lok S; Jacobsen S E
Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3.
Blood 1996;88(12):4481-92.
1996: Borge O J; Ramsfjell V; Veiby O P; Murphy M J; Lok S; Jacobsen S E
Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro.
Blood 1996;88(8):2859-70.
1996: Veiby O P; Jacobsen F W; Cui L; Lyman S D; Jacobsen S E
The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):2953-60.
1996: Jacobsen F W; Veiby O P; Stokke T; Jacobsen S E
TNF-alpha bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(3):1193-9.
1996: Veiby O P; Lyman S D; Jacobsen S E
Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.
Blood 1996;88(4):1256-65.
1996: Jacobsen S E; Veiby O P; Myklebust J; Okkenhaug C; Lyman S D
Ability of flt3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha.
Blood 1996;87(12):5016-26.
1996: Rusten L S; Dybedal I; Blomhoff H K; Blomhoff R; Smeland E B; Jacobsen S E
The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells.
Blood 1996;87(5):1728-36.
1996: Rusten L S; Lyman S D; Veiby O P; Jacobsen S E
The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro.
Blood 1996;87(4):1317-25.
1996: Jacobsen S E; Borge O J; Ramsfjell V; Cui L; Cardier J E; Veiby O P; Murphy M J; Lok S
Thrombopoietin, a direct stimulator of viability and multilineage growth of primitive bone marrow progenitor cells.
Stem cells (Dayton, Ohio) 1996;14 Suppl 1():173-80.
1996: Cardier J E; Foster D C; Lok S; Jacobsen S E; Murphy M J
Megakaryocytopoiesis in vitro: from the stem cells' perspective.
Stem cells (Dayton, Ohio) 1996;14 Suppl 1():163-72.
1995: Jacobsen F W; Stokke T; Jacobsen S E
Transforming growth factor-beta potently inhibits the viability-promoting activity of stem cell factor and other cytokines and induces apoptosis of primitive murine hematopoietic progenitor cells.
Blood 1995;86(8):2957-66.
1995: Jacobsen F W; Keller J R; Ruscetti F W; Veiby O P; Jacobsen S E
Direct synergistic effects of IL-4 and IL-11 on proliferation of primitive hematopoietic progenitor cells.
Experimental hematology 1995;23(9):990-5.
1995: Dybedal I; Jacobsen S E
Transforming growth factor beta (TGF-beta), a potent inhibitor of erythropoiesis: neutralizing TGF-beta antibodies show erythropoietin as a potent stimulator of murine burst-forming unit erythroid colony formation in the absence of a burst-promoting activity.
Blood 1995;86(3):949-57.
1995: Fahlman C; Jacobsen S E; Smeland E B; Lømo J; Naess C E; Funderud S; Blomhoff H K
All-trans- and 9-cis-retinoic acid inhibit growth of normal human and murine B cell precursors.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(1):58-65.
1995: Dybedal I; Larsen S; Jacobsen S E
IL-12 directly enhances in vitro murine erythropoiesis in combination with IL-4 and stem cell factor.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(10):4950-5.
1995: Jacobsen F W; Dubois C M; Rusten L S; Veiby O P; Jacobsen S E
Inhibition of stem cell factor-induced proliferation of primitive murine hematopoietic progenitor cells signaled through the 75-kilodalton tumor necrosis factor receptor. Regulation of c-kit and p53 expression.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3732-41.
1995: Jacobsen S E; Okkenhaug C; Myklebust J; Veiby O P; Lyman S D
The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors.
The Journal of experimental medicine 1995;181(4):1357-63.
1995: Rusten L S; Jacobsen S E
Tumor necrosis factor (TNF)-alpha directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptors.
Blood 1995;85(4):989-96.
1995: Grzegorzewski K J; Komschlies K L; Jacobsen S E; Ruscetti F W; Keller J R; Wiltrout R H
Mobilization of long-term reconstituting hematopoietic stem cells in mice by recombinant human interleukin 7.
The Journal of experimental medicine 1995;181(1):369-74.
1994: Smeland E B; Rusten L; Jacobsen S E; Skrede B; Blomhoff R; Wang M Y; Funderud S; Kvalheim G; Blomhoff H K
All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells.
Blood 1994;84(9):2940-5.
1994: Jacobsen S E; Ruscetti F W; Okkenhaug C; Lien E; Ortiz M; Veiby O P; Keller J R
Distinct and direct synergistic effects of IL-1 and IL-6 on proliferation and differentiation of primitive murine hematopoietic progenitor cells in vitro.
Experimental hematology 1994;22(11):1064-9.
1994: Keller J R; Bartelmez S H; Sitnicka E; Ruscetti F W; Ortiz M; Gooya J M; Jacobsen S E
Distinct and overlapping direct effects of macrophage inflammatory protein-1 alpha and transforming growth factor beta on hematopoietic progenitor/stem cell growth.
Blood 1994;84(7):2175-81.
1994: Jacobsen F W; Rothe M; Rusten L; Goeddel D V; Smeland E B; Veiby O P; Slørdal L; Jacobsen S E
Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10695-9.
1994: Jacobsen S E; Ruscetti F W; Ortiz M; Gooya J M; Keller J R
The growth response of Lin-Thy-1+ hematopoietic progenitors to cytokines is determined by the balance between synergy of multiple stimulators and negative cooperation of multiple inhibitors.
Experimental hematology 1994;22(10):985-9.
1994: Fahlman C; Jacobsen F W; Veiby O P; McNiece I K; Blomhoff H K; Jacobsen S E
Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors.
Blood 1994;84(5):1528-33.
1994: Rusten L S; Jacobsen S E; Kaalhus O; Veiby O P; Funderud S; Smeland E B
Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells.
Blood 1994;84(5):1473-81.
1994: Fahlman C; Blomhoff H K; Veiby O P; McNiece I K; Jacobsen S E
Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro.
Blood 1994;84(5):1450-6.
1994: Jacobsen F W; Rusten L S; Jacobsen S E
Direct synergistic effects of interleukin-7 on in vitro myelopoiesis of human CD34+ bone marrow progenitors.
Blood 1994;84(3):775-9.
1994: Jacobsen F W; Veiby O P; Jacobsen S E
IL-7 stimulates CSF-induced proliferation of murine bone marrow macrophages and Mac-1+ myeloid progenitors in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(1):270-6.
1994: Rusten L S; Smeland E B; Jacobsen F W; Lien E; Lesslauer W; Loetscher H; Dubois C M; Jacobsen S E
Tumor necrosis factor-alpha inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. Role of p55 and p75 tumor necrosis factor receptors.
The Journal of clinical investigation 1994;94(1):165-72.
1994: Jacobsen S E; Okkenhaug C; Veiby O P; Caput D; Ferrara P; Minty A
Interleukin 13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells.
The Journal of experimental medicine 1994;180(1):75-82.
1994: Rusten L S; Jacobsen F W; Lesslauer W; Loetscher H; Smeland E B; Jacobsen S E
Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors.
Blood 1994;83(11):3152-9.
1994: Jacobsen S E; Fahlman C; Blomhoff H K; Okkenhaug C; Rusten L S; Smeland E B
All-trans- and 9-cis-retinoic acid: potent direct inhibitors of primitive murine hematopoietic progenitors in vitro.
The Journal of experimental medicine 1994;179(5):1665-70.
1994: Jacobsen S E; Jacobsen F W; Fahlman C; Rusten L S
TNF-alpha, the great imitator: role of p55 and p75 TNF receptors in hematopoiesis.
Stem cells (Dayton, Ohio) 1994;12 Suppl 1():111-26; discussion 126-8.
1993: Jacobsen F W; Veiby O P; Skjønsberg C; Jacobsen S E
Novel role of interleukin 7 in myelopoiesis: stimulation of primitive murine hematopoietic progenitor cells.
The Journal of experimental medicine 1993;178(5):1777-82.
1993: Jacobsen S E; Veiby O P; Smeland E B
Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells.
The Journal of experimental medicine 1993;178(2):413-8.
1993: Hestdal K; Jacobsen S E; Ruscetti F W; Longo D L; Boone T C; Keller J R
Increased granulopoiesis after sequential administration of transforming growth factor-beta 1 and granulocyte-macrophage colony-stimulating factor.
Experimental hematology 1993;21(6):799-805.
1992: Hestdal K; Jacobsen S E; Ruscetti F W; Dubois C M; Longo D L; Chizzonite R; Oppenheim J J; Keller J R
In vivo effect of interleukin-1 alpha on hematopoiesis: role of colony-stimulating factor receptor modulation.
Blood 1992;80(10):2486-94.
1992: Keller J R; Jacobsen S E; Dubois C M; Hestdal K; Ruscetti F W
Transforming growth factor-beta: a bidirectional regulator of hematopoietic cell growth.
International journal of cell cloning 1992;10(1):2-11.
1991: Keller J R; Jacobsen S E; Sill K T; Ellingsworth L R; Ruscetti F W
Stimulation of granulopoiesis by transforming growth factor beta: synergy with granulocyte/macrophage-colony-stimulating factor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7190-4.
1991: Hestdal K; Ruscetti F W; Ihle J N; Jacobsen S E; Dubois C M; Kopp W C; Longo D L; Keller J R
Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(1):22-8.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Sten Eirik Jacobsen

Research Profile (preview)

Anatomy

Living Beings

Physiology

Chemicals & Drugs

Concepts & Ideas

Procedures

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Sten Eirik Jacobsen (preview)

All Publications