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Mikila Jacobson

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Charles Pilette; C Ratajczak; J VanSnick; G Banfield; Bruno Detry; Stephen R Durham; Mikila R Jacobson; Kayhan T Nouri-Aria
Aberrant dendritic cell function conditions Th2-cell polarization in allergic rhinitis.
A O Eifan; K Furukido; Mikila R Jacobson; G Banfield; A Dumitru; Stephen R Durham; Carsten B Schmidt-Weber; Kayhan T Nouri-Aria
Reduced T-bet in addition to enhanced STAT6 and GATA3 expressing T cells contribute to human allergen-induced late responses.
Louisa K James; Mohamed H Shamji; Samantha M Walker; Duncan R Wilson; Petra A Wachholz; James Francis; Mikila R Jacobson; Ian Kimber; Stephen Till; Stephen R Durham
Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies.

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All Publications

2013: Charles Pilette; C Ratajczak; J VanSnick; G Banfield; Bruno Detry; Stephen R Durham; Mikila R Jacobson; Kayhan T Nouri-Aria
Aberrant dendritic cell function conditions Th2-cell polarization in allergic rhinitis.
Allergy 2013;68(3):312-21.
2012: A O Eifan; K Furukido; Mikila R Jacobson; G Banfield; A Dumitru; Stephen R Durham; Carsten B Schmidt-Weber; Kayhan T Nouri-Aria
Reduced T-bet in addition to enhanced STAT6 and GATA3 expressing T cells contribute to human allergen-induced late responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2012;42(6):891-900.
2011: Louisa K James; Mohamed H Shamji; Samantha M Walker; Duncan R Wilson; Petra A Wachholz; James Francis; Mikila R Jacobson; Ian Kimber; Stephen Till; Stephen R Durham
Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies.
The Journal of allergy and clinical immunology 2011;127(2):509-516.e1-5.
2010: G Banfield; H Watanabe; Glenis Scadding; Mikila R Jacobson; Stephen Till; D A Hall; Douglas S Robinson; Clare M Lloyd; Kayhan T Nouri-Aria; Stephen R Durham
CC chemokine receptor 4 (CCR4) in human allergen-induced late nasal responses.
Allergy 2010;65(9):1126-33.
2010: G W Scadding; M H Shamji; Mikila R Jacobson; D I Lee; D Wilson; M Torres Lima; L Pitkin; Charles Pilette; Kayhan T Nouri-Aria; Stephen R Durham
Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3-expressing cells and elevated allergen-specific immunoglobulin G4, immunoglobulin A and serum inhibitory activity for immunoglobulin E-facilitated allergen binding to B cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(4):598-606.
2008: Suzana Radulovic; Mikila R Jacobson; Stephen R Durham; Kayhan T Nouri-Aria
Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa.
The Journal of allergy and clinical immunology 2008;121(6):1467-72, 1472.e1.
2007: Charles Pilette; Kayhan T Nouri-Aria; Mikila R Jacobson; Louisa K Wilcock; Bruno Detry; Samantha M Walker; James Francis; Stephen R Durham
Grass pollen immunotherapy induces an allergen-specific IgA2 antibody response associated with mucosal TGF-beta expression.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4658-66.
2006: Meinir G Jones; Alison Floyd; Kayhan T Nouri-Aria; Mikila R Jacobson; Stephen R Durham; Anthony Newman Taylor; Paul Cullinan
Is occupational asthma to diisocyanates a non-IgE-mediated disease?
The Journal of allergy and clinical immunology 2006;117(3):663-9.
2005: Kayhan T Nouri-Aria; Charles Pilette; Mikila R Jacobson; Hiroshi Watanabe; Stephen R Durham
IL-9 and c-Kit+ mast cells in allergic rhinitis during seasonal allergen exposure: effect of immunotherapy.
The Journal of allergy and clinical immunology 2005;116(1):73-9.
2005: Peter H Howarth; Carl G A Persson; Eli O Meltzer; Mikila R Jacobson; Stephen R Durham; Philip E Silkoff
Objective monitoring of nasal airway inflammation in rhinitis.
The Journal of allergy and clinical immunology 2005;115(3 Suppl 1):S414-41.
2004: Kayhan T Nouri-Aria; Petra A Wachholz; James Francis; Mikila R Jacobson; Samantha M Walker; Louisa K Wilcock; Steven Q Staple; Robert C Aalberse; Stephen Till; Stephen R Durham
Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3252-9.
2004: James Francis; Mikila R Jacobson; Clare M Lloyd; Ian Sabroe; Stephen R Durham; Stephen Till
CXCR1+CD4+ T cells in human allergic disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):268-73.
2002: Kayhan T Nouri-Aria; Duncan Wilson; James Francis; Louise A Jopling; Mikila R Jacobson; Martin R Hodge; David Andrew; Stephen Till; Eva-Maria Varga; Timothy J Williams; James E Pease; Clare M Lloyd; Ian Sabroe; Stephen R Durham
CCR4 in human allergen-induced late responses in the skin and lung.
European journal of immunology 2002;32(7):1933-8.
2001: Duncan R Wilson; A M Irani; Samantha M Walker; Mikila R Jacobson; Ian S Mackay; L B Schwartz; Stephen R Durham
Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(11):1705-13.
2001: Kayhan T Nouri-Aria; A M Irani; Mikila R Jacobson; F O'Brien; Eva-Maria Varga; Stephen Till; Stephen R Durham; L B Schwartz
Basophil recruitment and IL-4 production during human allergen-induced late asthma.
The Journal of allergy and clinical immunology 2001;108(2):205-11.
2001: Duncan R Wilson; Kayhan T Nouri-Aria; Samantha M Walker; G B Pajno; F O'Brien; Mikila R Jacobson; Ian S Mackay; Stephen R Durham
Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season.
The Journal of allergy and clinical immunology 2001;107(6):971-6.
2001: Stephen Till; Mikila R Jacobson; F O'Brien; Stephen R Durham; Alex KleinJan; Wytske J Fokkens; S Juliusson; Olle Löwhagen
Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy.
Allergy 2001;56(2):126-31.
1999: Stephen R Durham; VA Varney; M Gaga; Mikila R Jacobson; Eva-Maria Varga; Anthony J Frew; A Barry Kay
Grass pollen immunotherapy decreases the number of mast cells in the skin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(11):1490-6.
1999: Mikila R Jacobson; S Juliusson; Olle Löwhagen; Barbro Balder; A Barry Kay; Stephen R Durham
Effect of topical corticosteroids on seasonal increases in epithelial eosinophils and mast cells in allergic rhinitis: a comparison of nasal brush and biopsy methods.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(10):1347-55.
1999: Eva-Maria Varga; Mikila R Jacobson; K Masuyama; Sabina Rak; Stephen Till; Yvonne Darby; Qutayba Hamid; Valerie Lund; Glenis Scadding; Stephen R Durham
Inflammatory cell populations and cytokine mRNA expression in the nasal mucosa in aspirin-sensitive rhinitis.
The European respiratory journal 1999;14(3):610-5.
1999: Stephen R Durham; Samantha M Walker; Eva-Maria Varga; Mikila R Jacobson; F O'Brien; W Noble; Stephen Till; Qutayba A Hamid; Kayhan T Nouri-Aria
Long-term clinical efficacy of grass-pollen immunotherapy.
The New England journal of medicine 1999;341(7):468-75.
1999: Eva-Maria Varga; Mikila R Jacobson; Stephen Till; K Masuyama; F O'Brien; Sabina Rak; Valerie Lund; Glenis Scadding; Qutayba A Hamid; Stephen R Durham
Cellular infiltration and cytokine mRNA expression in perennial allergic rhinitis.
Allergy 1999;54(4):338-45.
1998: Kayhan T Nouri-Aria; K Masuyama; Mikila R Jacobson; Sabina Rak; O Lowhagen; E Schotman; Qutayba Hamid; Stephen Durham
Granulocyte/macrophage-colony stimulating factor in allergen-induced rhinitis: cellular localization, relation to tissue eosinophilia and influence of topical corticosteroid.
International archives of allergy and immunology 1998;117(4):248-54.
1998: K Masuyama; Stephen Till; Mikila R Jacobson; A Kamil; Lisa Cameron; S Juliusson; O Lowhagen; A Barry Kay; Qutayba A Hamid; Stephen R Durham
Nasal eosinophilia and IL-5 mRNA expression in seasonal allergic rhinitis induced by natural allergen exposure: effect of topical corticosteroids.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):610-7.
1998: LA Cameron; Stephen R Durham; Mikila R Jacobson; K Masuyama; S Juliusson; HJ Gould; O Lowhagen; EM Minshall; Qutayba A Hamid
Expression of IL-4, Cepsilon RNA, and Iepsilon RNA in the nasal mucosa of patients with seasonal rhinitis: effect of topical corticosteroids.
The Journal of allergy and clinical immunology 1998;101(3):330-6.
1997: Stephen R Durham; HJ Gould; CP Thienes; Mikila R Jacobson; K Masuyama; Sabina Rak; O Lowhagen; E Schotman; Lisa Cameron; Qutayba A Hamid
Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid.
European journal of immunology 1997;27(11):2899-906.
1997: O Ghaffar; Sophie Laberge; Mikila R Jacobson; O Lowhagen; Sabina Rak; Stephen R Durham; Qutayba Hamid
IL-13 mRNA and immunoreactivity in allergen-induced rhinitis: comparison with IL-4 expression and modulation by topical glucocorticoid therapy.
American journal of respiratory cell and molecular biology 1997;17(1):17-24.
1997: Qutayba A Hamid; E Schotman; Mikila R Jacobson; Samantha M Walker; Stephen R Durham
Increases in IL-12 messenger RNA+ cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy.
The Journal of allergy and clinical immunology 1997;99(2):254-60.
1996: Stephen R Durham; Sun Ying; V A Varney; Mikila R Jacobson; R M Sudderick; Ian S Mackay; A Barry Kay; Qutayba A Hamid
Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma.
The Journal of allergy and clinical immunology 1996;97(6):1356-65.
1995: Samantha M Walker; V A Varney; M Gaga; Mikila R Jacobson; Stephen R Durham
Grass pollen immunotherapy: efficacy and safety during a 4-year follow-up study.
Allergy 1995;50(5):405-13.
1994: A Tsicopoulos; Qutayba Hamid; Angela Haczku; Mikila R Jacobson; Stephen R Durham; J North; Julia Barkans; Christopher J Corrigan; Qiu Meng; Redwan Moqbel
Kinetics of cell infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals.
The Journal of allergy and clinical immunology 1994;94(4):764-72.
1994: Sabina Rak; Mikila R Jacobson; R M Sudderick; K Masuyama; S Juliusson; A Barry Kay; Qutayba Hamid; Olle Löwhagen; Stephen R Durham
Influence of prolonged treatment with topical corticosteroid (fluticasone propionate) on early and late phase nasal responses and cellular infiltration in the nasal mucosa after allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1994;24(10):930-9.
1994: Sun Ying; Stephen R Durham; Mikila R Jacobson; Sabina Rak; K Masuyama; O Lowhagen; A Barry Kay; Qutayba A Hamid
T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis.
Immunology 1994;82(2):200-6.
1994: K Masuyama; Mikila R Jacobson; Sabina Rak; Qiu Meng; R M Sudderick; A Barry Kay; O Lowhagen; Qutayba Hamid; Stephen R Durham
Topical glucocorticosteroid (fluticasone propionate) inhibits cells expressing cytokine mRNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis.
Immunology 1994;82(2):192-9.
1992: V A Varney; Mikila R Jacobson; R M Sudderick; Douglas S Robinson; A M Irani; L B Schwartz; Ian S Mackay; A Barry Kay; Stephen R Durham
Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils.
The American review of respiratory disease 1992;146(1):170-6.
1992: Stephen R Durham; Sun Ying; V A Varney; Mikila R Jacobson; R M Sudderick; Ian S Mackay; A Barry Kay; Qutayba A Hamid
Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2390-4.
1992: A M Bentley; Mikila R Jacobson; V Cumberworth; Julia Barkans; Redwan Moqbel; L B Schwartz; A M Irani; A Barry Kay; Stephen R Durham
Immunohistology of the nasal mucosa in seasonal allergic rhinitis: increases in activated eosinophils and epithelial mast cells.
The Journal of allergy and clinical immunology 1992;89(4):877-83.