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Michel Jadot

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Isabelle Hamer; Thierry Arnould; Guillaume Van Beersel; Michel Jadot
Lipids and lysosomes.
Benedicte Andre; Cecile Duterme; Michel Jadot; Jeannine Mertens-Strijthagen; Kris Van Moer; Bruno Flamion
Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase.
Sayali S Dixit; Michel Jadot; David E Sleat; Istvan Sohar; Ann M Stock; Peter Lobel
Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway.

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All Publications

2012: Isabelle Hamer; Thierry Arnould; Guillaume Van Beersel; Michel Jadot
Lipids and lysosomes.
Current drug metabolism 2012;13(10):1371-87.
2011: Benedicte Andre; Cecile Duterme; Michel Jadot; Jeannine Mertens-Strijthagen; Kris Van Moer; Bruno Flamion
Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase.
Biochemical and biophysical research communications 2011;411(1):175-9.
2011: Sayali S Dixit; Michel Jadot; David E Sleat; Istvan Sohar; Ann M Stock; Peter Lobel
Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway.
PloS one 2011;6(8):e23677.
2010: Su Xu; David E Sleat; Michel Jadot; Peter Lobel
Glial fibrillary acidic protein is elevated in the lysosomal storage disease classical late-infantile neuronal ceroid lipofuscinosis, but is not a component of the storage material.
The Biochemical journal 2010;428(3):355-62.
2009: Isabelle Hamer; Edouard Delaive; Marc Dieu; Fadi Abdel-Sater; Ludovic Mercy; Michel Jadot; Thierry Arnould
Up-regulation of cathepsin B expression and enhanced secretion in mitochondrial DNA-depleted osteosarcoma cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 2009;101(1):31-41.
2008: Pengling Sun; David E Sleat; Michèle Lecocq; Alison R Hayman; Michel Jadot; Peter Lobel
Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16590-5.
2008: Marielle Boonen; Roberta Rezende de Castro; Gaëlle Cuvelier; Isabelle Hamer; Michel Jadot
A dileucine signal situated in the C-terminal tail of the lysosomal membrane protein p40 is responsible for its targeting to lysosomes.
The Biochemical journal 2008;414(3):431-40.
2008: M-C Gasingirwa; J Thirion; C Costa; Bruno Flamion; Peter Lobel; Michel Jadot
A method to assess the lysosomal residence of proteins in cultured cells.
Analytical biochemistry 2008;374(1):31-40.
2007: David E Sleat; Michel Jadot; Peter Lobel
Lysosomal proteomics and disease.
Proteomics. Clinical applications 2007;1(9):1134-46.
2007: Robert Wattiaux; Simone Wattiaux-De Coninck; Jacqueline Thirion; Mańe-Christine Gasingirwa; Michel Jadot
Lysosomes and Fas-mediated liver cell death.
The Biochemical journal 2007;403(1):89-95.
2007: Rikke Nielsen; Pierre J Courtoy; Christian Jacobsen; Geneviève Dom; Wânia Rezende Lima; Michel Jadot; Thomas E Willnow; Olivier Devuyst; Erik I Christensen
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5407-12.
2007: Anaïs G Jensen; Magali Chemali; Agnès Chapel; Sylvie Kieffer-Jaquinod; Michel Jadot; Jérôme Garin; Agnès Journet
Biochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463).
The Biochemical journal 2007;402(3):449-58.
2006: Maria Cecilia Della Valle; David E Sleat; Istvan Sohar; Ting Wen; John E Pintar; Michel Jadot; Peter Lobel
Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.
The Journal of biological chemistry 2006;281(46):35436-45.
2006: Marielle Boonen; Isabelle Hamer; Muriel Boussac; Anne-Françoise Delsaute; Bruno Flamion; Jérôme Garin; Michel Jadot
Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes.
The Biochemical journal 2006;395(1):39-47.
2005: Isabelle Hamer; Michel Jadot
Endolysosomal transport of newly-synthesized cathepsin D in a sucrose model of lysosomal storage.
Experimental cell research 2005;309(2):284-95.
2004: Ralph Jans; Ganka Atanasova; Michel Jadot; Yves Poumay
Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.
The Journal of investigative dermatology 2004;123(3):564-73.
2004: Fanjam Andrianaivo; Michèle Lecocq; Simone Wattiaux-De Coninck; Robert Wattiaux; Michel Jadot
Hydrodynamics-based transfection of the liver: entrance into hepatocytes of DNA that causes expression takes place very early after injection.
The journal of gene medicine 2004;6(8):877-83.
2004: Ralph Jans; Marc Sartor; Michel Jadot; Yves Poumay
Calcium entry into keratinocytes induces exocytosis of lysosomes.
Archives of dermatological research 2004;296(1):30-41.
2003: Jacqueline Thirion; Robert Wattiaux; Michel Jadot
The acid phosphatase positive organelles of the Giardia lamblia trophozoite contain a membrane bound cathepsin C activity.
Biology of the cell / under the auspices of the European Cell Biology Organization 2003;95(2):99-105.
2003: Michèle Lecocq; Fanjam Andrianaivo; Marie-Thérèse Warnier; Simone Wattiaux-De Coninck; Robert Wattiaux; Michel Jadot
Uptake by mouse liver and intracellular fate of plasmid DNA after a rapid tail vein injection of a small or a large volume.
The journal of gene medicine 2003;5(2):142-56.
2002: Virginie Santilman; Michel Jadot; Francis Mainferme
Importance of the propeptide in the biosynthetic maturation of rat cathepsin C.
European journal of cell biology 2002;81(12):654-63.
2002: Melwin Colaço; MM Bapat; Sandra Misquith; Michel Jadot; Simone Wattiaux-De Coninck; Robert Wattiaux
Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver.
Biochemical and biophysical research communications 2002;296(5):1180-5.
2001: Michel Jadot; Fanjam Andrianaivo; F Dubois; Robert Wattiaux
Effects of methylcyclodextrin on lysosomes.
European journal of biochemistry / FEBS 2001;268(5):1392-9.
2000: Saule Naureckiene; David E Sleat; Henry Lackland; AH Fensom; marie T vanier; Robert Wattiaux; Michel Jadot; Peter Lobel
Identification of HE1 as the second gene of Niemann-Pick C disease.
Science (New York, N.Y.) 2000;290(5500):2298-301.
2000: Michèle Lecocq; Simone Wattiaux-De Coninck; N Laurent; Robert Wattiaux; Michel Jadot
Uptake and intracellular fate of polyethylenimine in vivo.
Biochemical and biophysical research communications 2000;278(2):414-8.
2000: Robert Wattiaux; N Laurent; Simone Wattiaux-De Coninck; Michel Jadot
Endosomes, lysosomes: their implication in gene transfer.
Advanced drug delivery reviews 2000;41(2):201-8.
1999: Istvan Sohar; David E Sleat; Michel Jadot; Peter Lobel
Biochemical characterization of a lysosomal protease deficient in classical late infantile neuronal ceroid lipofuscinosis (LINCL) and development of an enzyme-based assay for diagnosis and exclusion of LINCL in human specimens and animal models.
Journal of neurochemistry 1999;73(2):700-11.
1999: Michel Jadot; L Lin; David E Sleat; Istvan Sohar; Ming-Sing Hsu; John E Pintar; F Dubois; Simone Wattiaux-De Coninck; Robert Wattiaux; Peter Lobel
Subcellular localization of mannose 6-phosphate glycoproteins in rat brain.
The Journal of biological chemistry 1999;274(30):21104-13.
1999: N Laurent; Simone Wattiaux-De Coninck; E Mihaylova; E Leontieva; M T Warnier-Pirotte; Robert Wattiaux; Michel Jadot
Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-L-lysine or poly-D-lysine.
FEBS letters 1999;443(1):61-5.
1998: A Gilbert; Michel Jadot; E Leontieva; Simone Wattiaux-De Coninck; Robert Wattiaux
Delta F508 CFTR localizes in the endoplasmic reticulum-Golgi intermediate compartment in cystic fibrosis cells.
Experimental cell research 1998;242(1):144-52.
1998: V Sarafian; Michel Jadot; J M Foidart; Jean-Jacques LETESSON; F Van den Brûle; V Castronovo; Robert Wattiaux; S W Coninck
Expression of Lamp-1 and Lamp-2 and their interactions with galectin-3 in human tumor cells.
International journal of cancer. Journal international du cancer 1998;75(1):105-11.
1997: Robert Wattiaux; Michel Jadot; M T Warnier-Pirotte; Simone Wattiaux-De Coninck
Cationic lipids destabilize lysosomal membrane in vitro.
FEBS letters 1997;417(2):199-202.
1997: Michel Jadot; F Dubois; Simone Wattiaux-De Coninck; Robert Wattiaux
Supramolecular assemblies from lysosomal matrix proteins and complex lipids.
European journal of biochemistry / FEBS 1997;249(3):862-9.
1996: Robert Wattiaux; Michel Jadot; N Laurent; F Dubois; Simone Wattiaux-De Coninck
Cationic lipids delay the transfer of plasmid DNA to lysosomes.
Biochemical and biophysical research communications 1996;227(2):448-54.
1996: Michel Jadot; Robert Wattiaux; F Mainferme; F Dubois; A Claessens; Simone Wattiaux-De Coninck
Soluble form of Lamp II in purified rat liver lysosomes.
Biochemical and biophysical research communications 1996;223(2):353-9.
1996: Robert Wattiaux; Michel Jadot; F Dubois; Simone Wattiaux-De Coninck
Phagocytosis by rat liver: relationships between phagosomes and lysosomes.
Biochemical and biophysical research communications 1996;220(3):569-74.
1995: Robert Wattiaux; Michel Jadot; F Dubois; S Misquith; Simone Wattiaux-De Coninck
Uptake of exogenous DNA by rat liver: effect of cationic lipids.
Biochemical and biophysical research communications 1995;213(1):81-7.
1994: C Tans; F Dubois; Z D Zhong; Michel Jadot; Robert Wattiaux; Simone Wattiaux-De Coninck
Uptake by rat liver of bovine growth hormone free or bound to a monoclonal antibody.
Biology of the cell / under the auspices of the European Cell Biology Organization 1994;82(1):45-9.
1993: Robert Wattiaux; F Gentinne; Michel Jadot; F Dubois; Simone Wattiaux-De Coninck
Chloroquine allows to distinguish between hepatocyte lysosomes and sinusoidal cell lysosomes.
Biochemical and biophysical research communications 1993;190(3):808-13.
1993: Robert Wattiaux; Michel Jadot; S Misquith; Simone Wattiaux-De Coninck
Characterization of endocytic components of liver nonparenchymal cells.
Sub-cellular biochemistry 1993;19():163-94.
1992: Z D Zhong; Michel Jadot; Simone Wattiaux-De Coninck; Robert Wattiaux
Uptake of tyramine cellobiose by rat liver.
Biochimica et biophysica acta 1992;1106(2):311-6.
1990: Michel Jadot; V Biélande; V Beauloye; Simone Wattiaux-De Coninck; Robert Wattiaux
Cytotoxicity and effect of glycyl-D-phenylalanine-2-naphthylamide on lysosomes.
Biochimica et biophysica acta 1990;1027(2):205-9.
1989: Michel Jadot; Simone Wattiaux-De Coninck; Robert Wattiaux
The permeability of lysosomes to sugars. Effect of diethylstilbestrol on the osmotic activation of lysosomes induced by glucose.
The Biochemical journal 1989;262(3):981-4.
1986: Michel Jadot; S Misquith; F Dubois; Simone Wattiaux-De Coninck; Robert Wattiaux
Intracellular pathway followed by invertase endocytosed by rat liver.
European journal of biochemistry / FEBS 1986;161(3):695-700.
1986: Robert Wattiaux; Michel Jadot; S Misquith; F Dubois; Simone Wattiaux-De Coninck
Differences in the cellular location of substances endocytosed by rat liver as observed from the distribution patterns obtained after isopycnic centrifugation in a sucrose gradient.
Biochemical and biophysical research communications 1986;136(2):504-9.
1985: Michel Jadot; Simone Wattiaux-De Coninck; Robert Wattiaux
Effect on lysosomes of invertase endocytosed by rat-liver.
European journal of biochemistry / FEBS 1985;151(3):485-8.
1985: Michel Jadot; Robert Wattiaux
Effect of glycyl-L-phenylalanine 2-naphthylamide on invertase endocytosed by rat liver.
The Biochemical journal 1985;225(3):645-8.
1984: Michel Jadot; C Colmant; Simone Wattiaux-De Coninck; Robert Wattiaux
Intralysosomal hydrolysis of glycyl-L-phenylalanine 2-naphthylamide.
The Biochemical journal 1984;219(3):965-70.