FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Rudolf Jaenisch

Research Profile

Living Beings

Physiology

Anatomy

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Yosef Buganim; Dina A Faddah; Rudolf Jaenisch
Mechanisms and models of somatic cell reprogramming.
Haoyi Wang; Hui Yang; Feng Zhang; Albert Cheng; Meelad M Dawlaty; Chikdu S Shivalila; Rudolf Jaenisch
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering.
Francesco M Piccolo; Jorge Soza-Ried; Takashi Tada; Hakan Bagci; Karen E Brown; Meelad M Dawlaty; Amelie Feytout; Petra Hajkova; Rudolf Jaenisch; Skirmantas Kriaucionis; David Landeira; Harry G Leitch; Matthias Merkenschlager; Dylan Mooijman; Amanda G Fisher
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Rudolf Jaenisch (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yosef Buganim; Dina A Faddah; Rudolf Jaenisch
Mechanisms and models of somatic cell reprogramming.
Nature reviews. Genetics 2013;14(6):427-39.
2013: Haoyi Wang; Hui Yang; Feng Zhang; Albert Cheng; Meelad M Dawlaty; Chikdu S Shivalila; Rudolf Jaenisch
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering.
Cell 2013;153(4):910-8.
2013: Francesco M Piccolo; Jorge Soza-Ried; Takashi Tada; Hakan Bagci; Karen E Brown; Meelad M Dawlaty; Amelie Feytout; Petra Hajkova; Rudolf Jaenisch; Skirmantas Kriaucionis; David Landeira; Harry G Leitch; Matthias Merkenschlager; Dylan Mooijman; Amanda G Fisher
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Molecular cell 2013;49(6):1023-33.
2013: Meelad M Dawlaty; Kym F Faull; Qing Gao; Thuc Le; Zhe Li; Frank Lyko; Benjamin E Powell; Günter Raddatz; Mingjiang Xu; M Inmaculada Barrasa; Achim Breiling; Albert Cheng; Rudolf Jaenisch
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Developmental cell 2013;24(3):310-23.
2013: Michael A Lodato; Christopher W Ng; Kevin K Thai; Joseph A Wamstad; Albert W Cheng; Ernest Fraenkel; Rudolf Jaenisch; Laurie A Boyer
SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state.
PLoS genetics 2013;9(2):e1003288.
2013: Ana M Avalos; Rudolf Jaenisch; You-Me Kim; Oktay Kirak; J Margit Oelkers; Matthias Ottinger; Marina C Pils; Hidde L Ploegh; Melanie M Brinkmann
Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(2):695-702.
2013: Akihiro Hirata; Konrad Hochedlinger; Rudolf Jaenisch; Takahiro Kunisada; Hideyuki Okano; Toshikazu Ushijima; Jochen Utikal; Akira Watanabe; Hitomi Aoki; Nabeel Bardeesy; Akira Hara; Takuya Yamamoto; Satoshi Yamashita; Yasuhiro Yamada
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium.
Development (Cambridge, England) 2013;140(1):66-75.
2012: Yosef Buganim; Rudolf Jaenisch
Transdifferentiation by defined factors as a powerful research tool to address basic biological questions.
Cell cycle (Georgetown, Tex.) 2012;11(24):4485-6.
2012: Rudolf Jaenisch
Nuclear cloning and direct reprogramming: the long and the short path to Stockholm.
Cell stem cell 2012;11(6):744-7.
2012: Frank Soldner; Rudolf Jaenisch
Medicine. iPSC disease modeling.
Science (New York, N.Y.) 2012;338(6111):1155-6.
2012: Yosef Buganim; Albert Cheng; Dina A Faddah; Kibibi Ganz; Elena Itskovich; Sandy L Klemm; Styliani Markoulaki; Alexander van Oudenaarden; Rudolf Jaenisch
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.
Cell 2012;150(6):1209-22.
2012: Yosef Buganim; Albert Cheng; Dongdong Fu; Kibibi Ganz; Yueh-Chiang Hu; Elena Itskovich; David C Page; Sovan Sarkar; G Grant Welstead; Rudolf Jaenisch
Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors.
Cell stem cell 2012;11(3):373-86.
2012: Stephanie K Dougan; Gijsbert M Grotenbreg; Eduardo Guillen; Chih-Chi Andrew Hu; Rudolf Jaenisch; Souichi Ogata; Hidde L Ploegh
IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13739-44.
2012: G Grant Welstead; Richard A Young; Styliani Markoulaki; Steve Bilodeau; Albert Cheng; Menno P Creyghton; Rudolf Jaenisch
X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(32):13004-9.
2012: Günter Raddatz; Sebastian Bender; Qing Gao; Rudolf Jaenisch; Frank Lyko
Dnmt3a protects active chromosome domains against cancer-associated hypomethylation.
PLoS genetics 2012;8(12):e1003146.
2011: Bryce W Carey; John P Cassady; Menno P Creyghton; Dina A Faddah; Kibibi Ganz; Qing Gao; Jacob H Hanna; Jongpil Kim; Styliani Markoulaki; Eveline J Steine; G Grant Welstead; Yosef Buganim; Rudolf Jaenisch
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells.
Cell stem cell 2011;9(6):588-98.
2011: Krishanu Saha; Jing Yang; Morgan R Alexander; Daniel G Anderson; Martyn C Davies; Robert Langer; Ying Mei; Julien Muffat; Neena Kenton Pyzocha; Colin M Reisterer; Rudolf Jaenisch
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):18714-9.
2011: Jongpil Kim; Christopher J Lengner; Michael A Lodato; Susan C Su; Li-Huei Tsai; Haoyi Wang; John P Cassady; Albert Cheng; Chee-Yeun Chung; Meelad M Dawlaty; Rudolf Jaenisch
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts.
Cell stem cell 2011;9(5):413-9.
2011: Qing Gao; Dirk Hockemeyer; M Inmaculada Barrasa; George W Bell; Dongdong Fu; Mathias Pawlak; Seshamma Reddy; Eveline J Steine; Rudolf Jaenisch
Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(44):18061-6.
2011: Li-Fang Chu; Rudolf Jaenisch; M Azim Surani; Thomas P Zwaka
Blimp1 expression predicts embryonic stem cell development in vitro.
Current biology : CB 2011;21(20):1759-65.
2011: Lea A Medeiros; David C Page; Phillip A Sharp; Amy C White; Lucas M Dennis; Dongdong Fu; Mark E Gill; Hristo Houbaviy; Oktay Kirak; Styliani Markoulaki; Rudolf Jaenisch
Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14163-8.
2011: Meelad M Dawlaty; Kibibi Ganz; Qing Gao; Yueh-Chiang Hu; Jongpil Kim; Styliani Markoulaki; David C Page; Benjamin E Powell; Albert Cheng; Sang-Woon Choi; Rudolf Jaenisch
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Cell stem cell 2011;9(2):166-75.
2011: Dirk Hockemeyer; John P Cassady; Jennifer M Cherone; Gregory J Cost; Qing Gao; Philip D Gregory; Sarah J Hinkley; Samira Kiani; Christine S Lai; Xiangdong Meng; Jeffrey C Miller; Edward J Rebar; Yolanda Santiago; Fyodor D Urnov; Haoyi Wang; Bryan Zeitler; Lei Zhang; Rudolf Jaenisch
Genetic engineering of human pluripotent cells using TALE nucleases.
Nature biotechnology 2011;29(8):731-4.
2011: Frank Soldner; Fyodor D Urnov; B Joseph Vu; H Steve Zhang; Lei Zhang; Vikram Khurana; Josée Laganière; Susan Lindquist; Xiangdong Meng; Richard H Myers; Edward J Rebar; RK Alagappan; Albert Cheng; Lauren K Fong; Qing Gao; Lawrence I Golbe; Philip D Gregory; D Guschin; Dirk Hockemeyer; Rudolf Jaenisch
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Cell 2011;146(2):318-31.
2011: Judith Staerk; Lubica Supekova; Shoutian Zhu; Michael Bollong; Laure C Bouchez; Achim Brinker; Bradley D Charette; Charles Y Cho; Ruth K Foreman; Qing Gao; Michael Garcia; Rudolf Jaenisch; Jeffrey Janes; Luke L Lairson; Costas A Lyssiotis; Lea A Medeiro; Peter G Schultz
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Angewandte Chemie (International ed. in English) 2011;50(25):5734-6.
2011: Jongpil Kim; Christopher J Lengner; Oktay Kirak; Jacob Hanna; John P Cassady; Michael A Lodato; Su Wu; Dina A Faddah; Eveline J Steine; Qing Gao; Dongdong Fu; Meelad Dawlaty; Rudolf Jaenisch
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors.
Stem cells (Dayton, Ohio) 2011;29(6):992-1000.
2011: Mathias Pawlak; Rudolf Jaenisch
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state.
Genes & development 2011;25(10):1035-40.
2011: Grace X Y Zheng; Arvind Ravi; J Mauro Calabrese; Lea A Medeiros; Oktay Kirak; Lucas M Dennis; Rudolf Jaenisch; Christopher B Burge; Phillip A Sharp
A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells.
PLoS genetics 2011;7(5):e1002054.
2011: Eveline J Steine; Mathias Ehrich; George W Bell; Arjun Raj; Seshamma Reddy; Alexander van Oudenaarden; Rudolf Jaenisch; Heinz G Linhart
Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer.
The Journal of clinical investigation 2011;121(5):1748-52.
2011: Tamara Major; Jayanthi Menon; Frank Soldner; Gordon Auyeung; Dirk Hockemeyer; Rudolf Jaenisch; Vivian S Tabar
Transgene excision has no impact on in vivo integration of human iPS derived neural precursors.
PloS one 2011;6(9):e24687.
2010: Menno P Creyghton; Albert W Cheng; G Grant Welstead; Tristan Kooistra; Bryce W Carey; Eveline J Steine; Jacob Hanna; Michael A Lodato; Garrett M Frampton; Phillip A Sharp; Laurie A Boyer; Richard A Young; Rudolf Jaenisch
Histone H3K27ac separates active from poised enhancers and predicts developmental state.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(50):21931-6.
2010: Jacob H Hanna; Krishanu Saha; Rudolf Jaenisch
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues.
Cell 2010;143(4):508-25.
2010: Thomas Serwold; Konrad Hochedlinger; John Swindle; Joe Hedgpeth; Rudolf Jaenisch; Irving L Weissman
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):18939-43.
2010: K Kim; A Doi; Bo Wen; K Ng; R Zhao; Patrick Cahan; Jonghwan Kim; Martin Aryee; Hongxiu Ji; L I R Ehrlich; A Yabuuchi; A Takeuchi; K C Cunniff; H Hongguang; S McKinney-Freeman; O Naveiras; T J Yoon; Rafael A Irizarry; N Jung; J Seita; J Hanna; P Murakami; Rudolf Jaenisch; R Weissleder; S H Orkin; I L Weissman; Andrew P Feinberg; George Q Daley
Epigenetic memory in induced pluripotent stem cells.
Nature 2010;467(7313):285-90.
2010: Brenna L Brady; Michael A Oropallo; Katherine S Yang-Iott; Thomas Serwold; Konrad Hochedlinger; Rudolf Jaenisch; Irving L Weissman; Craig H Bassing
Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3564-73.
2010: Gunnar Hargus; Oliver Cooper; Michela Deleidi; Adam Levy; Kristen Lee; Elizabeth Marlow; Alyssa Yow; Frank Soldner; Dirk Hockemeyer; Penelope J Hallett; Teresia Osborn; Rudolf Jaenisch; Ole Isacson
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(36):15921-6.
2010: Ying Mei; Krishanu Saha; Said R Bogatyrev; Jing Yang; Andrew L Hook; Z Ilke Kalcioglu; Seung-Woo Cho; Maisam Mitalipova; Neena Pyzocha; Fredrick Rojas; Krystyn J Van Vliet; Martyn C Davies; Morgan R Alexander; Robert Langer; Rudolf Jaenisch; Daniel G Anderson
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells.
Nature materials 2010;9(9):768-78.
2010: Matthew G Guenther; Garrett M Frampton; Frank Soldner; Dirk Hockemeyer; Maisam Mitalipova; Rudolf Jaenisch; Richard A Young
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells.
Cell stem cell 2010;7(2):249-57.
2010: Michael G Kharas; Christopher J Lengner; Fatima Al-Shahrour; Lars Bullinger; Brian Ball; Samir Zaidi; Kelly Morgan; Winnie Tam; Mahnaz Paktinat; Rachel Okabe; Maricel Gozo; William Einhorn; Steven W Lane; Claudia Scholl; Stefan Fröhling; Mark Fleming; Benjamin L Ebert; D Gary Gilliland; Rudolf Jaenisch; George Q Daley
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.
Nature medicine 2010;16(8):903-8.
2010: Russell C DeKelver; Vivian M Choi; Erica A Moehle; David E Paschon; Dirk Hockemeyer; Sebastiaan H Meijsing; Yasemin Sancak; Xiaoxia Cui; Eveline J Steine; Jeffrey C Miller; Phillip Tam; Victor V Bartsevich; Xiangdong Meng; Igor Rupniewski; Sunita M Gopalan; Helena C Sun; Kathleen J Pitz; Jeremy M Rock; Lei Zhang; Gregory D Davis; Edward J Rebar; Iain M Cheeseman; Keith R Yamamoto; David M Sabatini; Rudolf Jaenisch; Philip D Gregory; Fyodor D Urnov
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
Genome research 2010;20(8):1133-42.
2010: Judith Staerk; Meelad M Dawlaty; Qing Gao; Dorothea Maetzel; Jacob Hanna; Cesar A Sommer; Gustavo Mostoslavsky; Rudolf Jaenisch
Reprogramming of human peripheral blood cells to induced pluripotent stem cells.
Cell stem cell 2010;7(1):20-4.
2010: Satoshi Namekawa; Bernhard Payer; Khanh D Huynh; Rudolf Jaenisch; Jeannie T Lee
Two-step imprinted X inactivation: repeat versus genic silencing in the mouse.
Molecular and cellular biology 2010;30(13):3187-205.
2010: Ralf Dressel; Jessica Nolte; Leslie Elsner; Peter Novota; Kaomei Guan; Katrin Streckfuss-Bömeke; Gerd Hasenfuss; Rudolf Jaenisch; Wolfgang Engel
Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(7):2164-77.
2010: Christopher J Lengner; Alexander A Gimelbrant; Jennifer A Erwin; Albert Wu Cheng; Matthew G Guenther; G Grant Welstead; RK Alagappan; Garrett M Frampton; Ping Xu; Julien Muffat; Sandro Santagata; Doug Powers; C Brent Barrett; Richard A Young; Jeannie T Lee; Rudolf Jaenisch; Maisam Mitalipova
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.
Cell 2010;141(5):872-83.
2010: Jan E Carette; Jan Pruszak; Malini Varadarajan; Vincent A Blomen; Sumita Gokhale; Fernando D Camargo; Marius Wernig; Rudolf Jaenisch; Thijn R Brummelkamp
Generation of iPSCs from cultured human malignant cells.
Blood 2010;115(20):4039-42.
2010: Jacob Hanna; Albert Cheng; Krishanu Saha; Jongpil Kim; Christopher J Lengner; Frank Soldner; John P Cassady; Julien Muffat; Bryce W Carey; Rudolf Jaenisch
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(20):9222-7.
2010: Maarten Zijlstra; Mark Bix; Neil E Simister; Janet M Loring; David H Raulet; Rudolf Jaenisch
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. 1990.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(9):4587-91.
2010: Oktay Kirak; Eva-Maria Frickel; Gijsbert M Grotenbreg; Heikyung Suh; Rudolf Jaenisch; Hidde L Ploegh
Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.
Science (New York, N.Y.) 2010;328(5975):243-8.
2010: Katherine S Yang-Iott; Andrea C Carpenter; Marta A W Rowh; Natalie Steinel; Brenna L Brady; Konrad Hochedlinger; Rudolf Jaenisch; Craig H Bassing
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1369-78.
2010: D Hockemeyer; Rudolf Jaenisch
Gene targeting in human pluripotent cells.
Cold Spring Harbor symposia on quantitative biology 2010;75():201-9.
2010: Oktay Kirak; Eva-Maria Frickel; Gijsbert M Grotenbreg; Heikyung Suh; Rudolf Jaenisch; Hidde L Ploegh
Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.
Journal of visualized experiments : JoVE 2010;(43):.
2010: Bryce W Carey; Styliani Markoulaki; Caroline Beard; Jacob Hanna; Rudolf Jaenisch
Single-gene transgenic mouse strains for reprogramming adult somatic cells.
Nature methods 2010;7(1):56-9.
2009: Krishanu Saha; Rudolf Jaenisch
Technical challenges in using human induced pluripotent stem cells to model disease.
Cell stem cell 2009;5(6):584-95.
2009: Jacob Hanna; Krishanu Saha; Bernardo Pando; Jeroen van Zon; Christopher J Lengner; Menno P Creyghton; Alexander van Oudenaarden; Rudolf Jaenisch
Direct cell reprogramming is a stochastic process amenable to acceleration.
Nature 2009;462(7273):595-601.
2009: Alexey Kuzmenkin; Huamin Liang; Guoxing Xu; Kurt Pfannkuche; Hardy Eichhorn; Azra Fatima; Hongyan Luo; Tomo Saric; Marius Wernig; Rudolf Jaenisch; Juergen Hescheler
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(12):4168-80.
2009: Ann-Marie Bröske; Lena Vockentanz; Shabnam Kharazi; Matthew Huska; Elena Mancini; Marina Scheller; Christiane Kuhl; Andreas Enns; Marco Prinz; Rudolf Jaenisch; Claus Nerlov; Achim Leutz; Miguel Andrade; Sten Eirik W Jacobsen; Frank Rosenbauer
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Nature genetics 2009;41(11):1207-15.
2009: Prakash K Rao; Yumiko Toyama; H Rosaria Chiang; Sumeet Gupta; Michael Bauer; Rostislav Medvid; Ferenc Reinhardt; Ronglih Liao; Monty Krieger; Rudolf Jaenisch; Harvey Lodish; Robert Blelloch
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure.
Circulation research 2009;105(6):585-94.
2009: Dirk Hockemeyer; Frank Soldner; Caroline Beard; Qing Gao; Maisam Mitalipova; Russell C DeKelver; George E Katibah; Ranier Amora; Elizabeth A Boydston; Bryan Zeitler; Xiangdong Meng; Jeffrey C Miller; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; Rudolf Jaenisch
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Nature biotechnology 2009;27(9):851-7.
2009: Rudolf Jaenisch
Stem cells, pluripotency and nuclear reprogramming.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():21-3.
2009: Jacob Hanna; Styliani Markoulaki; Maisam Mitalipova; Albert Cheng; John P Cassady; Judith Staerk; Bryce W Carey; Christopher J Lengner; Ruth Foreman; Jennifer Love; Qing Gao; Jongpil Kim; Rudolf Jaenisch
Metastable pluripotent states in NOD-mouse-derived ESCs.
Cell stem cell 2009;4(6):513-24.
2009: Costas A Lyssiotis; Ruth K Foreman; Judith Staerk; Michael Garcia; Divya Mathur; Styliani Markoulaki; Jacob Hanna; Luke L Lairson; Bradley D Charette; Laure C Bouchez; Michael Bollong; Conrad Kunick; Achim Brinker; Charles Y Cho; Peter G Schultz; Rudolf Jaenisch
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8912-7.
2009: Katsuhiko Nosho; Kaori Shima; Natsumi Irahara; Shoko Kure; Yoshifumi Baba; Gregory J Kirkner; Li Chen; Sumita Gokhale; Aditi Hazra; Donna Spiegelman; Edward L Giovannucci; Rudolf Jaenisch; Charles S Fuchs; Shuji Ogino
DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(11):3663-71.
2009: Ji-Song Guan; Stephen Haggarty; Emanuela Giacometti; Jan-Hermen Dannenberg; Nadine Joseph; Jun Gao; Thomas J F Nieland; Ying Zhou; Xinyu Wang; Ralph Mazitschek; James E Bradner; Ronald A DePinho; Rudolf Jaenisch; Li-Huei Tsai
HDAC2 negatively regulates memory formation and synaptic plasticity.
Nature 2009;459(7243):55-60.
2009: Dong Wook Han; Jeong Tae Do; Marcos J Arauzo-Bravo; Sung Ho Lee; Alexander Meissner; Hoon Taek Lee; Rudolf Jaenisch; Hans R Schöler
Epigenetic hierarchy governing Nestin expression.
Stem cells (Dayton, Ohio) 2009;27(5):1088-97.
2009: Jifang Tao; Keping Hu; Qiang Chang; Hao Wu; Nicholas E Sherman; Keri Martinowich; Robert J Klose; Carolyn Schanen; Rudolf Jaenisch; Weidong Wang; Yi E Sun
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(12):4882-7.
2009: Mitchell Guttman; Ido Amit; manuel garber; Courtney French; Michael F Lin; David M. Feldser; Maite Huarte; Or Zuk; Bryce W Carey; John P Cassady; Moran N Cabili; Rudolf Jaenisch; Tarjei S Mikkelsen; Tyler Jacks; Nir Hacohen; Bradley E Bernstein; Manolis Kellis; Aviv Regev; John L Rinn; Eric S Lander
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
Nature 2009;458(7235):223-7.
2009: Frank Soldner; Dirk Hockemeyer; Caroline Beard; Qing Gao; George W Bell; Elizabeth G Cook; Gunnar Hargus; Alexandra Blak; Oliver Cooper; Maisam Mitalipova; Ole Isacson; Rudolf Jaenisch
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors.
Cell 2009;136(5):964-77.
2009: George Q Daley; M William Lensch; Rudolf Jaenisch; Alex Meissner; Kathrin Plath; Shinya Yamanaka
Broader implications of defining standards for the pluripotency of iPSCs.
Cell stem cell 2009;4(3):200-1; author reply 202.
2009: Daniela Tropea; Emanuela Giacometti; Nathan R Wilson; Caroline Beard; Cortina McCurry; Dong Dong Fu; Ruth Flannery; Rudolf Jaenisch; Mriganka Sur
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):2029-34.
2009: Styliani Markoulaki; Jacob Hanna; Caroline Beard; Bryce W Carey; Albert Cheng; Christopher J Lengner; Jessica A Dausman; Dongdong Fu; Qing Gao; Su Wu; John P Cassady; Rudolf Jaenisch
Transgenic mice with defined combinations of drug-inducible reprogramming factors.
Nature biotechnology 2009;27(2):169-71.
2009: Alison M Skelley; Oktay Kirak; Heikyung Suh; Rudolf Jaenisch; Joel Voldman
Microfluidic control of cell pairing and fusion.
Nature methods 2009;6(2):147-52.
2009: Bryce W Carey; Styliani Markoulaki; Jacob Hanna; Krishanu Saha; Qing Gao; Maisam Mitalipova; Rudolf Jaenisch
Reprogramming of murine and human somatic cells using a single polycistronic vector.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):157-62.
2009: Kurt Pfannkuche; Huamin Liang; Tobias Hannes; Jiaoya Xi; Azra Fatima; Filomain Nguemo; Matthias Matzkies; Marius Wernig; Rudolf Jaenisch; Frank Pillekamp; Marcel Halbach; Heribert Schunkert; Tomo Sarić; Juergen Hescheler; Michael Reppel
Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(1-2):73-86.
2009: Alexander Meissner; Sarah Eminli; Rudolf Jaenisch
Derivation and manipulation of murine embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2009;482():3-19.
2009: Adlen Foudi; Konrad Hochedlinger; Denille Van Buren; Jeffrey W Schindler; Rudolf Jaenisch; Vincent Carey; Hanno Hock
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells.
Nature biotechnology 2009;27(1):84-90.
2009: Heinz G Linhart; Aron Troen; George W Bell; Erika Cantu; Wei-Hsun Chao; Eva Moran; Eveline Steine; Timothy He; Rudolf Jaenisch
Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.
Gastroenterology 2009;136(1):227-235.e3.
2008: Rudolf Jaenisch
Celebrating 10 years of hESC lines: an interview with Rudolf Jaenisch.
Stem cells (Dayton, Ohio) 2008;26(12):3005-7.
2008: Menno P Creyghton; Styliani Markoulaki; Stuart S Levine; Jacob Hanna; Michael A Lodato; Ky Sha; Richard A Young; Rudolf Jaenisch; Laurie A Boyer
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment.
Cell 2008;135(4):649-61.
2008: Jordan Green; Betty Y Zhou; Maisam M Mitalipova; Caroline Beard; Robert Langer; Rudolf Jaenisch; Daniel G Anderson
Nanoparticles for gene transfer to human embryonic stem cell colonies.
Nano letters 2008;8(10):3126-30.
2008: Sarah Eminli; Jochen Utikal; Katrin Arnold; Rudolf Jaenisch; Konrad Hochedlinger
Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression.
Stem cells (Dayton, Ohio) 2008;26(10):2467-74.
2008: Dirk Hockemeyer; Frank Soldner; Elizabeth G Cook; Qing Gao; Maisam Mitalipova; Rudolf Jaenisch
A drug-inducible system for direct reprogramming of human somatic cells to pluripotency.
Cell stem cell 2008;3(3):346-53.
2008: Alexander Marson; Stuart S Levine; Megan F Cole; Garrett M Frampton; Tobias Brambrink; Sarah E Johnstone; Matthew G Guenther; Wendy K Johnston; Marius Wernig; Jamie Newman; J Mauro Calabrese; Lucas M Dennis; Thomas L Volkert; Sumeet Gupta; Jennifer Love; Nancy M Hannett; Phillip A Sharp; David P Bartel; Rudolf Jaenisch; Richard A Young
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells.
Cell 2008;134(3):521-33.
2008: Alexander Marson; Ruth Foreman; Brett Chevalier; Steve Bilodeau; Michael Kahn; Richard A Young; Rudolf Jaenisch
Wnt signaling promotes reprogramming of somatic cells to pluripotency.
Cell stem cell 2008;3(2):132-5.
2008: Alexander Meissner; Tarjei S Mikkelsen; Hongcang Gu; Marius Wernig; Jacob Hanna; Andrey Sivachenko; Xiaolan Zhang; Bradley E Bernstein; Chad Nusbaum; David B Jaffe; Andreas Gnirke; Rudolf Jaenisch; Eric S Lander
Genome-scale DNA methylation maps of pluripotent and differentiated cells.
Nature 2008;454(7205):766-70.
2008: Rudolf Jaenisch
Interview with Rudolf Jaenisch, M.D.
Rejuvenation research 2008;11(4):849-50.
2008: Marius Wernig; Christopher J Lengner; Jacob Hanna; Michael A Lodato; Eveline Steine; Ruth Foreman; Judith Staerk; Styliani Markoulaki; Rudolf Jaenisch
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types.
Nature biotechnology 2008;26(8):916-24.
2008: Golo Kronenberg; Christoph Harms; Robert W Sobol; Fernando Cardozo-Pelaez; Heinz Linhart; Benjamin Winter; Mustafa Balkaya; Karen Gertz; Shanna B Gay; David Cox; Sarah Eckart; Michael Ahmadi; Georg Juckel; Gerd Kempermann; Rainer Hellweg; Reinhard Sohr; Heide Hörtnagl; Samuel H Wilson; Rudolf Jaenisch; Matthias Endres
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(28):7219-30.
2008: Tarjei S Mikkelsen; Jacob Hanna; Xiaolan Zhang; Manching Ku; Marius Wernig; Patrick Schorderet; Bradley E Bernstein; Rudolf Jaenisch; Eric S Lander; Alexander Meissner
Dissecting direct reprogramming through integrative genomic analysis.
Nature 2008;454(7200):49-55.
2008: Ryutaro Hirasawa; Hatsune Chiba; Masahiro Kaneda; Shoji Tajima; En Li; Rudolf Jaenisch; Hiroyuki Sasaki
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development.
Genes & development 2008;22(12):1607-16.
2008: Styliani Markoulaki; Alexander Meissner; Rudolf Jaenisch
Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse.
Methods (San Diego, Calif.) 2008;45(2):101-14.
2008: Jacob Hanna; Styliani Markoulaki; Patrick Schorderet; Bryce W Carey; Caroline Beard; Marius Wernig; Menno P Creyghton; Eveline J Steine; John P Cassady; Ruth Foreman; Christopher J Lengner; Jessica A Dausman; Rudolf Jaenisch
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency.
Cell 2008;133(2):250-64.
2008: Marius Wernig; Jian-Ping Zhao; Jan Pruszak; Eva Hedlund; Dongdong Fu; Frank Soldner; Vania Broccoli; Martha Constantine-Paton; Ole Isacson; Rudolf Jaenisch
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(15):5856-61.
2008: Christopher J Lengner; G Grant Welstead; Rudolf Jaenisch
The pluripotency regulator Oct4: a role in somatic stem cells?
Cell cycle (Georgetown, Tex.) 2008;7(6):725-8.
2008: Andrea Ventura; Amanda G Young; Monte M Winslow; Laura Lintault; Alexander Meissner; Stefan J Erkeland; Jamie Newman; Roderick T Bronson; Denise Crowley; James R Stone; Rudolf Jaenisch; Phillip A Sharp; Tyler Jacks
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.
Cell 2008;132(5):875-86.
2008: Rudolf Jaenisch; Richard Young
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming.
Cell 2008;132(4):567-82.
2008: Shaun D Fouse; Yin Shen; Matteo Pellegrini; Steve Cole; Alexander Meissner; Leander Van Neste; Rudolf Jaenisch; Guoping Fan
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation.
Cell stem cell 2008;2(2):160-9.
2008: Tobias Brambrink; Ruth Foreman; G Grant Welstead; Christopher J Lengner; Marius Wernig; Heikyung Suh; Rudolf Jaenisch
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells.
Cell stem cell 2008;2(2):151-9.
2008: Marius Wernig; Alexander Meissner; John P Cassady; Rudolf Jaenisch
c-Myc is dispensable for direct reprogramming of mouse fibroblasts.
Cell stem cell 2008;2(1):10-2.
2008: G Howard; Rachel Eiges; François Gaudet; Rudolf Jaenisch; Amir Eden
Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice.
Oncogene 2008;27(3):404-8.
2008: G Grant Welstead; Tobias Brambrink; Rudolf Jaenisch
Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4.
Journal of visualized experiments : JoVE 2008;(14):.
2008: J Hanna; B W Carey; Rudolf Jaenisch
Reprogramming of somatic cell identity.
Cold Spring Harbor symposia on quantitative biology 2008;73():147-55.
2008: Divya Mathur; Timothy Danford; Laurie A Boyer; Richard A Young; David K Gifford; Rudolf Jaenisch
Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET.
Genome biology 2008;9(8):R126.
2007: Jacob Hanna; Marius Wernig; Styliani Markoulaki; Chiao-Wang Sun; Alexander Meissner; John P Cassady; Caroline Beard; Tobias Brambrink; Li-Chen Wu; Tim M Townes; Rudolf Jaenisch
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.
Science (New York, N.Y.) 2007;318(5858):1920-3.
2007: Fernando D Camargo; Sumita Gokhale; Jonathan B Johnnidis; Dongdong Fu; George W Bell; Rudolf Jaenisch; Thijn R Brummelkamp
YAP1 increases organ size and expands undifferentiated progenitor cells.
Current biology : CB 2007;17(23):2054-60.
2007: Heinz Linhart; Haijiang Lin; Yasuhiro Yamada; Eva Moran; Eveline J Steine; Sumita Gokhale; Grace Lo; Erika Cantu; Mathias Ehrich; Timothy He; Alexander Meissner; Rudolf Jaenisch
Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.
Genes & development 2007;21(23):3110-22.
2007: Insoo Hyun; Konrad Hochedlinger; Rudolf Jaenisch; Shinya Yamanaka
New advances in iPS cell research do not obviate the need for human embryonic stem cells.
Cell stem cell 2007;1(4):367-8.
2007: Christopher J Lengner; Fernando D Camargo; Konrad Hochedlinger; G Grant Welstead; Samir Zaidi; Sumita Gokhale; Hans R Scholer; Alexey Tomilin; Rudolf Jaenisch
Oct4 expression is not required for mouse somatic stem cell self-renewal.
Cell stem cell 2007;1(4):403-15.
2007: Alexander Meissner; Marius Wernig; Rudolf Jaenisch
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells.
Nature biotechnology 2007;25(10):1177-81.
2007: Kitai Kim; Kitwa Ng; Peter J Rugg-Gunn; Jae-Hung Shieh; Oktay Kirak; Rudolf Jaenisch; Teruhiko Wakayama; Malcolm A S Moore; Roger A Pedersen; George Q Daley
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer.
Cell stem cell 2007;1(3):346-52.
2007: Tarjei S Mikkelsen; Manching Ku; David B Jaffe; Biju Issac; Erez Lieberman; Georgia Giannoukos; Pablo Alvarez; William Brockman; Tae Kyoung Kim; Richard P Koche; William Lee; Eric Mendenhall; Aisling O'Donovan; Aviva Presser; Carsten Russ; Xiaohui Xie; Alexander Meissner; Marius Wernig; Rudolf Jaenisch; Chad Nusbaum; Eric S Lander; Bradley E Bernstein
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
Nature 2007;448(7153):553-60.
2007: Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.
Nature 2007;448(7151):318-24.
2007: Thomas Serwold; Konrad Hochedlinger; Matthew A Inlay; Rudolf Jaenisch; Irving L Weissman
Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):928-38.
2007: Matthew G Guenther; Stuart S Levine; Laurie A Boyer; Rudolf Jaenisch; Richard A Young
A chromatin landmark and transcription initiation at most promoters in human cells.
Cell 2007;130(1):77-88.
2007: Jing Zhang; Yangang Liu; Caroline Beard; David A Tuveson; Rudolf Jaenisch; Tyler Jacks; Harvey Lodish
Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.
Blood 2007;109(12):5238-41.
2007: Nimet Maherali; Rupa Sridharan; Wei Xie; Jochen Utikal; Sarah Eminli; Katrin Arnold; Matthias Stadtfeld; Robin Yachechko; Jason Tchieu; Rudolf Jaenisch; Kathrin Plath; Konrad Hochedlinger
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.
Cell stem cell 2007;1(1):55-70.
2007: Suzanne Nguyen; Konstantinos Meletis; Dongdong Fu; Sonal Jhaveri; Rudolf Jaenisch
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(6):1663-76.
2007: Mats G Hansson; Gert Helgesson; Richard Wessman; Rudolf Jaenisch
Commentary: isolated stem cells--patentable as cultural artifacts?
Stem cells (Dayton, Ohio) 2007;25(6):1507-10.
2007: Alice T Shaw; Alexander Meissner; James A Dowdle; Denise Crowley; Margaret Magendantz; Chensi Ouyang; Tiziana Parisi; Jayaraj Rajagopal; Leah J Blank; Roderick T Bronson; James R Stone; David A Tuveson; Rudolf Jaenisch; Tyler Jacks
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.
Genes & development 2007;21(6):694-707.
2007: Yangming Wang; Rostislav Medvid; Collin Melton; Rudolf Jaenisch; Robert Blelloch
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal.
Nature genetics 2007;39(3):380-5.
2007: Emanuela Giacometti; Sandra Luikenhuis; Caroline Beard; Rudolf Jaenisch
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(6):1931-6.
2007: Konrad Hochedlinger; Rudolf Jaenisch
On the cloning of animals from terminally differentiated cells.
Nature genetics 2007;39(2):136-7; author reply 137-8.
2007: Kimberly D Siegmund; Caroline M Connor; Mihaela Campan; Tiffany I Long; Daniel J Weisenberger; Detlev Biniszkiewicz; Rudolf Jaenisch; Peter W Laird; Schahram Akbarian
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.
PloS one 2007;2(9):e895.
2006: Fabio Savarese; Katja Flahndorfer; Rudolf Jaenisch; Meinrad Busslinger; Anton Wutz
Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation.
Molecular and cellular biology 2006;26(19):7167-77.
2006: Laurie A Boyer; Divya Mathur; Rudolf Jaenisch
Molecular control of pluripotency.
Current opinion in genetics & development 2006;16(5):455-62.
2006: Alexander Meissner; Rudolf Jaenisch
Mammalian nuclear transfer.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(9):2460-9.
2006: Robert Blelloch; Zhongde Wang; Alexander Meissner; Steven Pollard; Austin Smith; Rudolf Jaenisch
Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.
Stem cells (Dayton, Ohio) 2006;24(9):2007-13.
2006: Konrad Hochedlinger; Rudolf Jaenisch
Nuclear reprogramming and pluripotency.
Nature 2006;441(7097):1061-7.
2006: Laurie A Boyer; Kathrin Plath; Julia Zeitlinger; Tobias Brambrink; Lea A Medeiros; Tong Ihn Lee; Stuart S Levine; Marius Wernig; Adriana Tajonar; Mridula K Ray; George W Bell; Arie P Otte; Miguel Vidal; David K Gifford; Richard A Young; Rudolf Jaenisch
Polycomb complexes repress developmental regulators in murine embryonic stem cells.
Nature 2006;441(7091):349-53.
2006: Kazuhiro Shimazu; Mingrui Zhao; Kazuko Sakata; Schahram Akbarian; Brian Bates; Rudolf Jaenisch; Bai Lu
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis.
Learning & memory (Cold Spring Harbor, N.Y.) 2006;13(3):307-15.
2006: Bradley E Bernstein; Tarjei S Mikkelsen; Xiaohui Xie; Michael Kamal; Dana J Huebert; James Cuff; Ben Fry; Alexander Meissner; Marius Wernig; Kathrin Plath; Rudolf Jaenisch; Alexandre Wagschal; Robert Feil; Stuart L Schreiber; Eric S Lander
A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Cell 2006;125(2):315-26.
2006: Tong Ihn Lee; Richard G Jenner; Laurie A Boyer; Matthew G Guenther; Stuart S Levine; Roshan M. Kumar; Brett Chevalier; Sarah E Johnstone; Megan F Cole; Kyo-ichi Isono; Haruhiko Koseki; Takuya Fuchikami; Kuniya Abe; Heather L Murray; Jacob P Zucker; Bingbing Yuan; George W Bell; Elizabeth Herbolsheimer; Nancy M Hannett; Kaiming Sun; Duncan T Odom; Arie P Otte; Thomas L Volkert; David P Bartel; Douglas A Melton; David K Gifford; Rudolf Jaenisch; Richard A Young
Control of developmental regulators by Polycomb in human embryonic stem cells.
Cell 2006;125(2):301-13.
2006: Craig Chappell; Caroline Beard; John D Altman; Rudolf Jaenisch; Joshy Jacob
DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4562-72.
2006: Haijiang Lin; Yasuhiro Yamada; Suzanne Nguyen; Heinz Linhart; Laurie Jackson-Grusby; Alexander Meissner; Konstantinos Meletis; Grace Lo; Rudolf Jaenisch
Suppression of intestinal neoplasia by deletion of Dnmt3b.
Molecular and cellular biology 2006;26(8):2976-83.
2006: Rudolf Jaenisch; Alex Meissner
Politically correct human embryonic stem cells?
The New England journal of medicine 2006;354(11):1208-9; author reply 1208-9.
2006: Maribel Rios; Evelyn K Lambe; Rongjian Liu; Sarah Teillon; JinHong Liu; Schahram Akbarian; Suzanne Roffler-Tarlov; Rudolf Jaenisch; George K Aghajanian
Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice.
Journal of neurobiology 2006;66(4):408-20.
2006: Terry Gemelli; Olivier Berton; Erika Nelson; Linda I Perrotti; Rudolf Jaenisch; Lisa M Monteggia
Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice.
Biological psychiatry 2006;59(5):468-76.
2006: Xiangzhong Yang; K Eggan; G Seidel; Rudolf Jaenisch; D Melton
A simple system of checks and balances to cut fraud.
Nature 2006;439(7078):782.
2006: Qiang Chang; Gargi Khare; Vardhan S Dani; Sacha Nelson; Rudolf Jaenisch
The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression.
Neuron 2006;49(3):341-8.
2006: Tobias Brambrink; Konrad Hochedlinger; George Bell; Rudolf Jaenisch
ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):933-8.
2006: Alexander Meissner; Rudolf Jaenisch
Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts.
Nature 2006;439(7073):212-5.
2006: S Eminli; Rudolf Jaenisch; Konrad Hochedlinger
Strategies to induce nuclear reprogramming.
Ernst Schering Foundation symposium proceedings 2006;(5):83-98.
2006: Caroline Beard; Konrad Hochedlinger; Kathrin Plath; Anton Wutz; Rudolf Jaenisch
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.
Genesis (New York, N.Y. : 2000) 2006;44(1):23-8.
2005: Teresa M Holm; Laurie Jackson-Grusby; Tobias Brambrink; Yasuhiro Yamada; William M Rideout; Rudolf Jaenisch
Global loss of imprinting leads to widespread tumorigenesis in adult mice.
Cancer cell 2005;8(4):275-85.
2005: Laurie A Boyer; Tong Ihn Lee; Megan F Cole; Sarah E Johnstone; Stuart S Levine; Jacob P Zucker; Matthew G Guenther; Roshan M. Kumar; Heather L Murray; Richard G Jenner; David K Gifford; Douglas A Melton; Rudolf Jaenisch; Richard A Young
Core transcriptional regulatory circuitry in human embryonic stem cells.
Cell 2005;122(6):947-56.
2005: Yasuhiro Yamada; Laurie Jackson-Grusby; Heinz Linhart; Alexander Meissner; Amir Eden; Haijiang Lin; Rudolf Jaenisch
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13580-5.
2005: Vardhan S Dani; Qiang Chang; Arianna Maffei; Gina G Turrigiano; Rudolf Jaenisch; Sacha B Nelson
Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12560-5.
2005: Hristo B Houbaviy; Lucas Dennis; Rudolf Jaenisch; Phillip A Sharp
Characterization of a highly variable eutherian microRNA gene.
RNA (New York, N.Y.) 2005;11(8):1245-57.
2005: Konrad Hochedlinger; Yasuhiro Yamada; Caroline Beard; Rudolf Jaenisch
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues.
Cell 2005;121(3):465-77.
2005: Yinghong Ma; Stephanie B Jacobs; Laurie Jackson-Grusby; Mary-Ann Mastrangelo; José A Torres-Betancourt; Rudolf Jaenisch; Theodore P Rasmussen
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A.
Journal of cell science 2005;118(Pt 8):1607-16.
2005: Sergei B Koralov; Tatiana I Novobrantseva; Konrad Hochedlinger; Rudolf Jaenisch; Klaus Rajewsky
Direct in vivo VH to JH rearrangement violating the 12/23 rule.
The Journal of experimental medicine 2005;201(3):341-8.
2005: Joost Gribnau; Sandra Luikenhuis; Konrad Hochedlinger; Kim Monkhorst; Rudolf Jaenisch
X chromosome choice occurs independently of asynchronous replication timing.
The Journal of cell biology 2005;168(3):365-73.
2005: Alexander Meissner; Andreas Gnirke; George W Bell; Bernard Ramsahoye; Eric S Lander; Rudolf Jaenisch
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis.
Nucleic acids research 2005;33(18):5868-77.
2005: Rudolf Jaenisch; Konrad Hochedlinger; Kevin Eggan
Nuclear cloning, epigenetic reprogramming and cellular differentiation.
Novartis Foundation symposium 2005;265():107-18; discussion 118-28.
2005: Alvin W Lyckman; Guoping Fan; Maribel Rios; Rudolf Jaenisch; Mriganka Sur
Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor.
Visual neuroscience 2005;22(1):27-36.
2004: Rudolf Jaenisch
Human cloning - the science and ethics of nuclear transplantation.
The New England journal of medicine 2004;351(27):2787-91.
2004: Kathrin Plath; Dale Talbot; Karien M Hamer; Arie P Otte; Thomas P Yang; Rudolf Jaenisch; Barbara Panning
Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome.
The Journal of cell biology 2004;167(6):1025-35.
2004: Enrico Mihich; Rudolf Jaenisch
Sixteenth Annual Pezcoller Symposium: stem cells and epigenesis in cancer.
Cancer research 2004;64(22):8474-7.
2004: Zhongde Wang; Rudolf Jaenisch
At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation.
Developmental biology 2004;275(1):192-201.
2004: Robert Blelloch; Konrad Hochedlinger; Yasuhiro Yamada; Cameron Brennan; Minjung Kim; Beatrice Mintz; Lynda Chin; Rudolf Jaenisch
Nuclear cloning of embryonal carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):13985-90.
2004: Nasim A Begum; Kazuo Kinoshita; Naoki Kakazu; Masamichi Muramatsu; Hitoshi Nagaoka; Reiko Shinkura; Detlev Biniszkiewicz; Laurie A Boyer; Rudolf Jaenisch; Tasuku Honjo
Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch.
Science (New York, N.Y.) 2004;305(5687):1160-3.
2004: Konrad Hochedlinger; Robert Blelloch; Cameron Brennan; Yasuhiro Yamada; Minjung Kim; Lynda Chin; Rudolf Jaenisch
Reprogramming of a melanoma genome by nuclear transplantation.
Genes & development 2004;18(15):1875-85.
2004: Andrea Ventura; Alexander Meissner; Christopher P Dillon; Michael McManus; Phillip A Sharp; Luk Van Parijs; Rudolf Jaenisch; Tyler Jacks
Cre-lox-regulated conditional RNA interference from transgenes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10380-5.
2004: Matthias Endres; Detlev Biniszkiewicz; Robert W Sobol; Christoph Harms; Michael Ahmadi; Andreas Lipski; Juri Katchanov; Philipp Mergenthaler; Ulrich Dirnagl; Samuel H Wilson; Andreas Meisel; Rudolf Jaenisch
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.
The Journal of clinical investigation 2004;113(12):1711-21.
2004: Sandra Luikenhuis; Emanuela Giacometti; Caroline F Beard; Rudolf Jaenisch
Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6033-8.
2004: Thomas A Natoli; Julia A Alberta; Alex Bortvin; Mary E Taglienti; Doug Menke; Janet Loring; Rudolf Jaenisch; David C Page; David E Housman; Jordan A Kreidberg
Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis.
Developmental biology 2004;268(2):429-40.
2004: Kevin Eggan; Kristin Baldwin; Michael Tackett; Joseph Osborne; Joseph A Gogos; Andrew Chess; Richard Axel; Rudolf Jaenisch
Mice cloned from olfactory sensory neurons.
Nature 2004;428(6978):44-9.
2004: François Gaudet; William M Rideout; Alexander Meissner; Jessica Dausman; Heinrich Leonhardt; Rudolf Jaenisch
Dnmt1 expression in pre- and postimplantation embryogenesis and the maintenance of IAP silencing.
Molecular and cellular biology 2004;24(4):1640-8.
2004: Rudolf Jaenisch; Konrad Hochedlinger; Robert Blelloch; Yasuhiro Yamada; K Baldwin; Kevin Eggan
Nuclear cloning, epigenetic reprogramming, and cellular differentiation.
Cold Spring Harbor symposia on quantitative biology 2004;69():19-27.
2004: Konrad Hochedlinger; William M Rideout; Michael Kyba; George Q Daley; Robert Blelloch; Rudolf Jaenisch
Nuclear transplantation, embryonic stem cells and the potential for cell therapy.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5 Suppl 3():S114-7.
2003: Kevin Eggan; Rudolf Jaenisch
Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation.
Seminars in cell & developmental biology 2003;14(6):349-58.
2003: Wen G. Chen; Qiang Chang; Yingxi Lin; Alexander Meissner; Anne E West; Eric C Griffith; Rudolf Jaenisch; Michael E Greenberg
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2.
Science (New York, N.Y.) 2003;302(5646):885-9.
2003: Konrad Hochedlinger; Rudolf Jaenisch
Nuclear transplantation, embryonic stem cells, and the potential for cell therapy.
The New England journal of medicine 2003;349(3):275-86.
2003: Frieder Schwenk; Branko Zevnik; Jens C Brüning; Mathias Röhl; Antje Willuweit; Anja Rode; Thomas Hennek; Gunther Kauselmann; Rudolf Jaenisch; Ralf Kühn
Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics.
Molecular and cellular biology 2003;23(11):3982-9.
2003: Ali H Brivanlou; Fred H Gage; Rudolf Jaenisch; Thomas Jessell; Douglas Melton; Janet Rossant
Stem cells. Setting standards for human embryonic stem cells.
Science (New York, N.Y.) 2003;300(5621):913-6.
2003: François Gaudet; J Graeme Hodgson; Amir Eden; Laurie Jackson-Grusby; Jessica Dausman; Joe Gray; Heinrich Leonhardt; Rudolf Jaenisch
Induction of tumors in mice by genomic hypomethylation.
Science (New York, N.Y.) 2003;300(5618):489-92.
2003: Amir Eden; François Gaudet; Alpana Waghmare; Rudolf Jaenisch
Chromosomal instability and tumors promoted by DNA hypomethylation.
Science (New York, N.Y.) 2003;300(5618):455.
2003: Alex Bortvin; Kevin Eggan; Helen Skaletsky; Hidenori Akutsu; Deborah L. Berry; Ryuzo Yanagimachi; David C Page; Rudolf Jaenisch
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.
Development (Cambridge, England) 2003;130(8):1673-80.
2003: Joost Gribnau; Konrad Hochedlinger; Ken Hata; En Li; Rudolf Jaenisch
Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.
Genes & development 2003;17(6):759-73.
2003: Thorsten Cramer; Yuji Yamanishi; Björn E Clausen; Irmgard Förster; Rafal Pawlinski; Nigel Mackman; Volker H Haase; Rudolf Jaenisch; Maripat Corr; Victor Nizet; Gary S Firestein; Hans-Peter Gerber; Napoleone Ferrara; Randall S Johnson
HIF-1alpha is essential for myeloid cell-mediated inflammation.
Cell 2003;112(5):645-57.
2003: Rudolf Jaenisch; Adrian Bird
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.
Nature genetics 2003;33 Suppl():245-54.
2003: Jost Seibler; Branko Zevnik; Birgit Küter-Luks; Susanne Andreas; Heidrun Kern; Thomas Hennek; Anja Rode; Cornelia Heimann; Nicole Faust; Gunther Kauselmann; Michael Schoor; Rudolf Jaenisch; Klaus Rajewsky; Ralf Kühn; Frieder Schwenk
Rapid generation of inducible mouse mutants.
Nucleic acids research 2003;31(4):e12.
2003: Matthias Endres; Guoping Fan; Lorenz Hirt; Rudolf Jaenisch
Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(2):150-3.
2003: Kevin Eggan; Rudolf Jaenisch
Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation.
Methods in enzymology 2003;365():25-39.
2002: Konrad Hochedlinger; Rudolf Jaenisch
Nuclear transplantation: lessons from frogs and mice.
Current opinion in cell biology 2002;14(6):741-8.
2002: John R McCarrey; Cathy Watson; Julia Atencio; G Charles Ostermeier; York Marahrens; Rudolf Jaenisch; Stephen A Krawetz
X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse.
Genesis (New York, N.Y. : 2000) 2002;34(4):257-66.
2002: Matthew Tudor; Schahram Akbarian; Richard Z Chen; Rudolf Jaenisch
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15536-41.
2002: James M A Turner; Shantha K Mahadevaiah; David J Elliott; Henri-Jean Garchon; John R Pehrson; Rudolf Jaenisch; Paul S Burgoyne
Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.
Journal of cell science 2002;115(Pt 21):4097-105.
2002: David Humpherys; Kevin Eggan; Hidenori Akutsu; Adam Friedman; Konrad Hochedlinger; Ryuzo Yanagimachi; Eric S Lander; Todd R Golub; Rudolf Jaenisch
Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12889-94.
2002: Schahram Akbarian; Maribel Rios; Rong-Jian Liu; Stephen J Gold; Hiu-Fai Fong; Steven R Zeiler; Vincenzo Coppola; Lino Tessarollo; Kevin R Jones; Eric J Nestler; George K Aghajanian; Rudolf Jaenisch
Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(10):4153-62.
2002: Kevin Eggan; Anja Rode; Isabell Jentsch; Caroline Samuel; Thomas Hennek; Hartmut Tintrup; Branko Zevnik; Jennifer Erwin; Janet Loring; Laurie Jackson-Grusby; Michael R Speicher; Ralf Kuehn; Rudolf Jaenisch
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation.
Nature biotechnology 2002;20(5):455-9.
2002: William M Rideout; Konrad Hochedlinger; Michael Kyba; George Q Daley; Rudolf Jaenisch
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy.
Cell 2002;109(1):17-27.
2002: Detlev Biniszkiewicz; Joost Gribnau; Bernard Ramsahoye; François Gaudet; Kevin Eggan; David Humpherys; Mary-Ann Mastrangelo; Zhan Jun; Jörn Walter; Rudolf Jaenisch
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.
Molecular and cellular biology 2002;22(7):2124-35.
2002: Konrad Hochedlinger; Rudolf Jaenisch
Monoclonal mice generated by nuclear transfer from mature B and T donor cells.
Nature 2002;415(6875):1035-8.
2002: Richard Possemato; Kevin Eggan; Benjamin J Moeller; Rudolf Jaenisch; Laurie Jackson-Grusby
Flp recombinase regulated lacZ expression at the ROSA26 locus.
Genesis (New York, N.Y. : 2000) 2002;32(2):184-6.
2002: Brian Bates; Lorenz Hirt; Sunu S Thomas; Schahram Akbarian; Dean Le; Sepideh Amin-Hanjani; Michael J Whalen; Rudolf Jaenisch; Michael A Moskowitz
Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals.
Neurobiology of disease 2002;9(1):24-37.
2002: Anton Wutz; Theodore P Rasmussen; Rudolf Jaenisch
Chromosomal silencing and localization are mediated by different domains of Xist RNA.
Nature genetics 2002;30(2):167-74.
2002: Rudolf Jaenisch
Nuclear cloning, embryonic stem cells, and transplantation therapy.
Harvey lectures 2002;98():145-71.
2001: Matthias Endres; G Fan; Andreas Meisel; Ulrich Dirnagl; Rudolf Jaenisch
Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons.
Neuroreport 2001;12(17):3763-6.
2001: Sandra Luikenhuis; A Wutz; Rudolf Jaenisch
Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells.
Molecular and cellular biology 2001;21(24):8512-20.
2001: Theodore P Rasmussen; Anton Wutz; J R Pehrson; Rudolf Jaenisch
Expression of Xist RNA is sufficient to initiate macrochromatin body formation.
Chromosoma 2001;110(6):411-20.
2001: P P Lee; David R Fitzpatrick; C Beard; Heidi K Jessup; Sophie M Lehar; Karen W Makar; Mercedes Pérez-Melgosa; M T Sweetser; M S Schlissel; S Nguyen; S R Cherry; J H Tsai; Suzanne M Tucker; William M Weaver; Anne Kelso; Rudolf Jaenisch; Christopher B Wilson
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.
Immunity 2001;15(5):763-74.
2001: Schahram Akbarian; Richard Z Chen; Joost Gribnau; Theodore P Rasmussen; H Fong; Rudolf Jaenisch; E G Jones
Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex.
Neurobiology of disease 2001;8(5):784-91.
2001: Maribel Rios; G Fan; C Fekete; J Kelly; Brian Bates; R Kuehn; R M Lechan; Rudolf Jaenisch
Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity.
Molecular endocrinology (Baltimore, Md.) 2001;15(10):1748-57.
2001: Schahram Akbarian; Brian Bates; Rong-Jian Liu; S L Skirboll; T Pejchal; Vincenzo Coppola; L D Sun; G Fan; Jan Kucera; M A Wilson; Lino Tessarollo; Barry E Kosofsky; J R Taylor; Mark Bothwell; Eric J Nestler; George K Aghajanian; Rudolf Jaenisch
Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal.
Molecular psychiatry 2001;6(5):593-604.
2001: William M Rideout; Kevin Eggan; Rudolf Jaenisch
Nuclear cloning and epigenetic reprogramming of the genome.
Science (New York, N.Y.) 2001;293(5532):1093-8.
2001: David Humpherys; Kevin Eggan; Hidenori Akutsu; Konrad Hochedlinger; William M Rideout; Detlev Biniszkiewicz; Ryuzo Yanagimachi; Rudolf Jaenisch
Epigenetic instability in ES cells and cloned mice.
Science (New York, N.Y.) 2001;293(5527):95-7.
2001: Kevin Eggan; Hidenori Akutsu; Janet Loring; Laurie Jackson-Grusby; M Klemm; William M Rideout; Ryuzo Yanagimachi; Rudolf Jaenisch
Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6209-14.
2001: G Csankovszki; Andras Nagy; Rudolf Jaenisch
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation.
The Journal of cell biology 2001;153(4):773-84.
2001: Anton Wutz; H C Theussl; Jessica Dausman; Rudolf Jaenisch; Denise P Barlow; E F Wagner
Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.
Development (Cambridge, England) 2001;128(10):1881-7.
2001: Rudolf Jaenisch; I Wilmut
Developmental biology. Don't clone humans!
Science (New York, N.Y.) 2001;291(5513):2552.
2001: Richard Z Chen; Schahram Akbarian; Matthew Tudor; Rudolf Jaenisch
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice.
Nature genetics 2001;27(3):327-31.
2001: Volker H Haase; J N Glickman; Merav Socolovsky; Rudolf Jaenisch
Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1583-8.
2001: G Fan; Caroline Beard; Richard Z Chen; G Csankovszki; Yi E Sun; MS Siniaia; Detlev Biniszkiewicz; Brian Bates; P P Lee; R Kuhn; Andreas Trumpp; C Poon; C B Wilson; Rudolf Jaenisch
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(3):788-97.
2001: G Fan; MS Siniaia; Chi-Sang Poon; Rudolf Jaenisch
Effect of DNA hypomethylation on neural control of respiration: a genetic model.
Advances in experimental medicine and biology 2001;499():195-200.
2001: Laurie Jackson-Grusby; Caroline Beard; Richard Possemato; Matthew Tudor; D Fambrough; G Csankovszki; Jessica Dausman; P Lee; C Wilson; Eric S Lander; Rudolf Jaenisch
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation.
Nature genetics 2001;27(1):31-9.
2000: F Lyko; Bernard Ramsahoye; Rudolf Jaenisch
DNA methylation in Drosophila melanogaster.
Nature 2000;408(6812):538-40.
2000: Kevin Eggan; Hidenori Akutsu; Konrad Hochedlinger; William M Rideout; Ryuzo Yanagimachi; Rudolf Jaenisch
X-Chromosome inactivation in cloned mouse embryos.
Science (New York, N.Y.) 2000;290(5496):1578-81.
2000: S R Cherry; Detlev Biniszkiewicz; Luk Van Parijs; David Baltimore; Rudolf Jaenisch
Retroviral expression in embryonic stem cells and hematopoietic stem cells.
Molecular and cellular biology 2000;20(20):7419-26.
2000: Theodore P Rasmussen; Mary-Ann Mastrangelo; Amir Eden; J R Pehrson; Rudolf Jaenisch
Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation.
The Journal of cell biology 2000;150(5):1189-98.
2000: S R Cherry; C Beard; Rudolf Jaenisch; David Baltimore
V(D)J recombination is not activated by demethylation of the kappa locus.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8467-72.
2000: F Lyko; AJ Whittaker; Terry L. Orr-Weaver; Rudolf Jaenisch
The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries.
Mechanisms of development 2000;95(1-2):215-7.
2000: G Fan; S Copray; E J Huang; K Jones; Q Yan; Jon M Walro; Rudolf Jaenisch; Jan Kucera
Formation of a full complement of cranial proprioceptors requires multiple neurotrophins.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;218(2):359-70.
2000: Bernard Ramsahoye; D Biniszkiewicz; F Lyko; V Clark; A P Bird; Rudolf Jaenisch
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5237-42.
2000: X Liu; Rudolf Jaenisch
Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;218(1):94-101.
2000: Matthias Endres; Andreas Meisel; Detlev Biniszkiewicz; Shobu Namura; Konstantin Prass; Karsten Ruscher; A Lipski; Rudolf Jaenisch; Michael A Moskowitz; Ulrich Dirnagl
DNA methyltransferase contributes to delayed ischemic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(9):3175-81.
2000: David Lombard; Caroline Beard; Brad Johnson; Robert Marciniak; Jessica Dausman; R Bronson; J E Buhlmann; R Lipman; R Curry; A Sharpe; Rudolf Jaenisch; Leonard Guarente
Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Molecular and cellular biology 2000;20(9):3286-91.
2000: Anton Wutz; Rudolf Jaenisch
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation.
Molecular cell 2000;5(4):695-705.
2000: G Fan; C Egles; Yi E Sun; L Minichiello; John Renger; R Klein; Guosong Liu; Rudolf Jaenisch
Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities.
Nature neuroscience 2000;3(4):350-7.
2000: F Brad Johnson; David Lombard; N F Neff; M A Mastrangelo; W Dewolf; Nathan Ellis; Robert Marciniak; Y Yin; Rudolf Jaenisch; Leonard Guarente
Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells.
Cancer research 2000;60(5):1162-7.
2000: William M Rideout; T Wakayama; Anton Wutz; Kevin Eggan; Laurie Jackson-Grusby; Jessica Dausman; Ryuzo Yanagimachi; Rudolf Jaenisch
Generation of mice from wild-type and targeted ES cells by nuclear cloning.
Nature genetics 2000;24(2):109-10.
2000: Matthias Endres; G Fan; Lorenz Hirt; M Fujii; Kohji Matsushita; X Liu; Rudolf Jaenisch; Michael A Moskowitz
Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(1):139-44.
1999: F Lyko; Bernard Ramsahoye; Helena Kashevsky; Matthew Tudor; Mary-Ann Mastrangelo; Terry L. Orr-Weaver; Rudolf Jaenisch
Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.
Nature genetics 1999;23(3):363-6.
1999: Matthew Tudor; Peter J Murray; C Onufryk; Rudolf Jaenisch; Richard A Young
Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice.
Genes & development 1999;13(18):2365-8.
1999: Theodore P Rasmussen; T Huang; Mary-Ann Mastrangelo; Janet Loring; Barbara Panning; Rudolf Jaenisch
Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing.
Nucleic acids research 1999;27(18):3685-9.
1999: M Tanaka; M Puchyr; Marina Gertsenstein; K Harpal; Rudolf Jaenisch; Janet Rossant; Andras Nagy
Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation.
Mechanisms of development 1999;87(1-2):129-42.
1999: A Sidow; MS Bulotsky; AW Kerrebrock; BW Birren; D Altshuler; Rudolf Jaenisch; K R Johnson; Eric S Lander
A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant.
Nature genetics 1999;23(1):104-7.
1999: G Csankovszki; B Panning; Brian Bates; J R Pehrson; Rudolf Jaenisch
Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation.
Nature genetics 1999;22(4):323-4.
1999: G Fan; Rudolf Jaenisch; Jan Kucera
A role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception.
Neuroscience 1999;90(1):259-68.
1999: Brian Bates; M Rios; Andreas Trumpp; C Chen; G Fan; John M Bishop; Rudolf Jaenisch
Neurotrophin-3 is required for proper cerebellar development.
Nature neuroscience 1999;2(2):115-7.
1999: MJ Donovan; Thomas A Natoli; Kirsi Sainio; A Amstutz; Rudolf Jaenisch; Hannu Sariola; Jordan A Kreidberg
Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud.
Developmental genetics 1999;24(3-4):252-62.
1998: François Gaudet; D Talbot; Heinrich Leonhardt; Rudolf Jaenisch
A short DNA methyltransferase isoform restores methylation in vivo.
The Journal of biological chemistry 1998;273(49):32725-9.
1998: Richard Z Chen; U Pettersson; Caroline Beard; Laurie Jackson-Grusby; Rudolf Jaenisch
DNA hypomethylation leads to elevated mutation rates.
Nature 1998;395(6697):89-93.
1998: Sheriar G Hormuzdi; Risto Penttinen; Rudolf Jaenisch; Paul Bornstein
A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene.
Molecular and cellular biology 1998;18(6):3368-75.
1998: Barbara Panning; Rudolf Jaenisch
RNA and the epigenetic regulation of X chromosome inactivation.
Cell 1998;93(3):305-8.
1998: Jan Kucera; G Fan; Jon M Walro; S Copray; L Tessarollo; Rudolf Jaenisch
Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles.
Neuroreport 1998;9(5):905-9.
1998: York Marahrens; Janet Loring; Rudolf Jaenisch
Role of the Xist gene in X chromosome choosing.
Cell 1998;92(5):657-64.
1998: Yun You; R Bersgtram; M Klemm; H Nelson; Rudolf Jaenisch; John C Schimenti
Utility of C57BL/6J x 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to gamma radiation and microsatellite polymorphism.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(3):232-4.
1998: Mirit I Aladjem; B T Spike; Luo-Wei Rodewald; TJ Hope; M Klemm; Rudolf Jaenisch; Geoffrey M Wahl
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage.
Current biology : CB 1998;8(3):145-55.
1998: Rudolf Jaenisch; Caroline Beard; Janice Y. Lee; York Marahrens; Barbara Panning
Mammalian X chromosome inactivation.
Novartis Foundation symposium 1998;214():200-9; discussion 209-13, 228-32.
1998: Peter M Warnecke; D Biniszkiewicz; Rudolf Jaenisch; Marianne Frommer; Susan J Clark
Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene.
Developmental genetics 1998;22(2):111-21.
1997: george feehehery; D Talbot; M Sha; J Benner; L Hornstra; E Li; Rudolf Jaenisch; Richard J Roberts
Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase.
Nucleic acids research 1997;25(22):4666-73.
1997: A Sidow; MS Bulotsky; AW Kerrebrock; RT Bronson; Mark J Daly; Mary Reeve; T L Hawkins; BW Birren; Rudolf Jaenisch; Eric S Lander
Serrate2 is disrupted in the mouse limb-development mutant syndactylism.
Nature 1997;389(6652):722-5.
1997: K Sabapathy; M Klemm; Rudolf Jaenisch; E F Wagner
Regulation of ES cell differentiation by functional and conformational modulation of p53.
The EMBO journal 1997;16(20):6217-29.
1997: S Sun; C Beard; Rudolf Jaenisch; P Jones; Jonathan Sprent
Mitogenicity of DNA from different organisms for murine B cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3119-25.
1997: K L Tucker; Y Wang; Jessica Dausman; Rudolf Jaenisch
A transgenic mouse strain expressing four drug-selectable marker genes.
Nucleic acids research 1997;25(18):3745-6.
1997: Barbara Panning; Jessica Dausman; Rudolf Jaenisch
X chromosome inactivation is mediated by Xist RNA stabilization.
Cell 1997;90(5):907-16.
1997: Rudolf Jaenisch
DNA methylation and imprinting: why bother?
Trends in genetics : TIG 1997;13(8):323-9.
1997: Y Wang; Rudolf Jaenisch
Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently.
Development (Cambridge, England) 1997;124(13):2507-13.
1997: M Di Fruscio; H Weiher; Barbara C Vanderhyden; T Imai; T Shiomi; T A Hori; Rudolf Jaenisch; Douglas A Gray
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.
Molecular and cellular biology 1997;17(7):4080-6.
1997: Shiuh-Wen Luoh; P A Bain; R D Polakiewicz; Mary Goodheart; H Gardner; Rudolf Jaenisch; David C Page
Zfx mutation results in small animal size and reduced germ cell number in male and female mice.
Development (Cambridge, England) 1997;124(11):2275-84.
1997: CM DiPersio; Kairbaan M Hodivala-Dilke; Rudolf Jaenisch; Jordan A Kreidberg; Richard O Hynes
alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.
The Journal of cell biology 1997;137(3):729-42.
1997: X Liu; H Wu; Janet Loring; Sheriar G Hormuzdi; C M Disteche; P Bornstein; Rudolf Jaenisch
Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;209(1):85-91.
1997: Laurie Jackson-Grusby; P W Laird; S N Magge; B J Moeller; Rudolf Jaenisch
Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4681-5.
1997: J T Lee; Rudolf Jaenisch
The (epi)genetic control of mammalian X-chromosome inactivation.
Current opinion in genetics & development 1997;7(2):274-80.
1997: J T Lee; Rudolf Jaenisch
Long-range cis effects of ectopic X-inactivation centres on a mouse autosome.
Nature 1997;386(6622):275-9.
1997: X Liu; H Wu; M Byrne; S Krane; Rudolf Jaenisch
Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1852-6.
1997: Yun You; R Bergstrom; M Klemm; B Lederman; H Nelson; C Ticknor; Rudolf Jaenisch; John C Schimenti
Chromosomal deletion complexes in mice by radiation of embryonic stem cells.
Nature genetics 1997;15(3):285-8.
1997: York Marahrens; Barbara Panning; Jessica Dausman; W Strauss; Rudolf Jaenisch
Xist-deficient mice are defective in dosage compensation but not spermatogenesis.
Genes & development 1997;11(2):156-66.
1996: J T Lee; Rudolf Jaenisch
A method for high efficiency YAC lipofection into murine embryonic stem cells.
Nucleic acids research 1996;24(24):5054-5.
1996: P D Soloway; C M Alexander; Z Werb; Rudolf Jaenisch
Targeted mutagenesis of Timp-1 reveals that lung tumor invasion is influenced by Timp-1 genotype of the tumor but not by that of the host.
Oncogene 1996;13(11):2307-14.
1996: K L Tucker; D Talbot; M A Lee; H Leonhardt; Rudolf Jaenisch
Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):12920-5.
1996: Stephen M Krane; M H Byrne; V Lemaître; Patrick Henriet; J J Jeffrey; J P Witter; X Liu; H Wu; Rudolf Jaenisch; Yves Eeckhout
Different collagenase gene products have different roles in degradation of type I collagen.
The Journal of biological chemistry 1996;271(45):28509-15.
1996: Jordan A Kreidberg; MJ Donovan; S L Goldstein; H Rennke; K Shepherd; R C Jones; Rudolf Jaenisch
Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis.
Development (Cambridge, England) 1996;122(11):3537-47.
1996: K Harbers; U Müller; A Grams; E Li; Rudolf Jaenisch; T Franz
Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12412-7.
1996: Laurie Jackson-Grusby; Rudolf Jaenisch
Experimental manipulation of genomic methylation.
Seminars in cancer biology 1996;7(5):261-8.
1996: M Luisa Iruela-Arispe; Robert B Vernon; H Wu; Rudolf Jaenisch; E Helene Sage
Type I collagen-deficient Mov-13 mice do not retain SPARC in the extracellular matrix: implications for fibroblast function.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;207(2):171-83.
1996: Hong Lei; S Paul Oh; Masaki Okano; R Jüttermann; K A Goss; Rudolf Jaenisch; En Li
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells.
Development (Cambridge, England) 1996;122(10):3195-205.
1996: Barbara Panning; Rudolf Jaenisch
DNA hypomethylation can activate Xist expression and silence X-linked genes.
Genes & development 1996;10(16):1991-2002.
1996: J T Lee; W M Strauss; Jessica Dausman; Rudolf Jaenisch
A 450 kb transgene displays properties of the mammalian X-inactivation center.
Cell 1996;86(1):83-94.
1996: H Schorle; P Meier; M Buchert; Rudolf Jaenisch; P J Mitchell
Transcription factor AP-2 essential for cranial closure and craniofacial development.
Nature 1996;381(6579):235-8.
1996: H Gardner; Jordan A Kreidberg; V Koteliansky; Rudolf Jaenisch
Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.
Developmental biology 1996;175(2):301-13.
1996: K L Tucker; Caroline Beard; J Dausmann; Laurie Jackson-Grusby; P W Laird; H Lei; E Li; Rudolf Jaenisch
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.
Genes & development 1996;10(8):1008-20.
1996: J Chun; Rudolf Jaenisch
Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses.
Molecular and cellular neurosciences 1996;7(4):304-21.
1996: Y Wang; P N Schnegelsberg; Jessica Dausman; Rudolf Jaenisch
Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin.
Nature 1996;379(6568):823-5.
1996: Wael ElShamy; Sten Linnarsson; K F Lee; Rudolf Jaenisch; Patrik Ernfors
Prenatal and postnatal requirements of NT-3 for sympathetic neuroblast survival and innervation of specific targets.
Development (Cambridge, England) 1996;122(2):491-500.
1996: Peter W Laird; Rudolf Jaenisch
The role of DNA methylation in cancer genetic and epigenetics.
Annual review of genetics 1996;30():441-64.
1995: J Kucera; G Fan; Rudolf Jaenisch; Sten Linnarsson; Patrik Ernfors
Dependence of developing group Ia afferents on neurotrophin-3.
The Journal of comparative neurology 1995;363(2):307-20.
1995: J Kucera; Patrik Ernfors; Jon M Walro; Rudolf Jaenisch
Reduction in the number of spinal motor neurons in neurotrophin-3-deficient mice.
Neuroscience 1995;69(1):321-30.
1995: H Wu; X Liu; Rudolf Jaenisch; Harvey Lodish
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor.
Cell 1995;83(1):59-67.
1995: P Ernfors; J Kucera; K F Lee; Janet Loring; Rudolf Jaenisch
Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice.
The International journal of developmental biology 1995;39(5):799-807.
1995: Caroline Beard; E Li; Rudolf Jaenisch
Loss of methylation activates Xist in somatic but not in embryonic cells.
Genes & development 1995;9(19):2325-34.
1995: X Liu; H Wu; M Byrne; J Jeffrey; S Krane; Rudolf Jaenisch
A targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodeling.
The Journal of cell biology 1995;130(1):227-37.
1995: Merab Kokaia; Patrik Ernfors; Zaal Kokaia; Eskil Elmér; Rudolf Jaenisch; Olle Lindvall
Suppressed epileptogenesis in BDNF mutant mice.
Experimental neurology 1995;133(2):215-24.
1995: P Ernfors; Thomas R Van De Water; Janet Loring; Rudolf Jaenisch
Complementary roles of BDNF and NT-3 in vestibular and auditory development.
Neuron 1995;14(6):1153-64.
1995: Rory Curtis; K M Adryan; J L Stark; JS Park; D L Compton; G Weskamp; L J Huber; M V Chao; Rudolf Jaenisch; K F Lee
Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins.
Neuron 1995;14(6):1201-11.
1995: X Liu; P Ernfors; H Wu; Rudolf Jaenisch
Sensory but not motor neuron deficits in mice lacking NT4 and BDNF.
Nature 1995;375(6528):238-41.
1995: P W Laird; Laurie Jackson-Grusby; A Fazeli; S L Dickinson; W E Jung; E Li; Robert A. Weinberg; Rudolf Jaenisch
Suppression of intestinal neoplasia by DNA hypomethylation.
Cell 1995;81(2):197-205.
1995: Martin M Matzuk; T Rajendra Kumar; Anne Vassalli; Jackie R Bickenbach; Dennis R Roop; Rudolf Jaenisch; Allan Bradley
Functional analysis of activins during mammalian development.
Nature 1995;374(6520):354-6.
1995: Michael A Rudnicki; Rudolf Jaenisch
The MyoD family of transcription factors and skeletal myogenesis.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(3):203-9.
1995: K Andrikopoulos; X Liu; Douglas R Keene; Rudolf Jaenisch; Francesco Ramirez
Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly.
Nature genetics 1995;9(1):31-6.
1994: R Jüttermann; E Li; Rudolf Jaenisch
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):11797-801.
1994: T Braun; Eva Bober; M A Rudnicki; Rudolf Jaenisch; Hans-Henning Arnold
MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice.
Development (Cambridge, England) 1994;120(11):3083-92.
1994: R Fässler; P N Schnegelsberg; Jessica Dausman; T Shinya; Y Muragaki; M T McCarthy; B R Olsen; Rudolf Jaenisch
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):5070-4.
1994: P Ernfors; K F Lee; J Kucera; Rudolf Jaenisch
Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents.
Cell 1994;77(4):503-12.
1994: K F Lee; A M Davies; Rudolf Jaenisch
p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF.
Development (Cambridge, England) 1994;120(4):1027-33.
1994: H Wu; X Liu; Rudolf Jaenisch
Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2819-23.
1994: K F Lee; K Bachman; S Landis; Rudolf Jaenisch
Dependence on p75 for innervation of some sympathetic targets.
Science (New York, N.Y.) 1994;263(5152):1447-9.
1994: P Ernfors; K F Lee; Rudolf Jaenisch
Mice lacking brain-derived neurotrophic factor develop with sensory deficits.
Nature 1994;368(6467):147-50.
1994: Linda S Wicker; E H Leiter; John A Todd; R J Renjilian; E Peterson; P A Fischer; PL Podolin; M Zijlstra; Rudolf Jaenisch; Laurence B Peterson
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes.
Diabetes 1994;43(3):500-4.
1994: Anne Vassalli; Martin M Matzuk; H A Gardner; K F Lee; Rudolf Jaenisch
Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.
Genes & development 1994;8(4):414-27.
1994: J Cable; D Huszar; Rudolf Jaenisch; Karen P Steel
Effects of mutations at the W locus (c-kit) on inner ear pigmentation and function in the mouse.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1994;7(1):17-32.
1994: P Ernfors; K F Lee; Rudolf Jaenisch
Target derived and putative local actions of neurotrophins in the peripheral nervous system.
Progress in brain research 1994;103():43-54.
1994: P W Laird; Rudolf Jaenisch
DNA methylation and cancer.
Human molecular genetics 1994;3 Spec No():1487-95.
1993: Michael A Rudnicki; P N Schnegelsberg; R H Stead; T Braun; H H Arnold; Rudolf Jaenisch
MyoD or Myf-5 is required for the formation of skeletal muscle.
Cell 1993;75(7):1351-9.
1993: S P Fenton; S R Lamande; M Hannagan; A Stacey; Rudolf Jaenisch; John F Bateman
Genomic sequence of mouse COL1A1 encoding the collagen propeptides.
Biochimica et biophysica acta 1993;1216(3):469-74.
1993: E Li; Caroline Beard; Rudolf Jaenisch
Role for DNA methylation in genomic imprinting.
Nature 1993;366(6453):362-5.
1993: J Bonadio; Karl Jepsen; MK Mansoura; Rudolf Jaenisch; J L Kuhn; Steven A Goldstein
A murine skeletal adaptation that significantly increases cortical bone mechanical properties. Implications for human skeletal fragility.
The Journal of clinical investigation 1993;92(4):1697-705.
1993: Alun M Davies; K F Lee; Rudolf Jaenisch
p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins.
Neuron 1993;11(4):565-74.
1993: RW Osorio; Nancy L Ascher; Rudolf Jaenisch; Chris E Freise; John P Roberts; Peter G Stock
Major histocompatibility complex class I deficiency prolongs islet allograft survival.
Diabetes 1993;42(10):1520-7.
1993: J A Kreidberg; H Sariola; J M Loring; M Maeda; J Pelletier; D Housman; Rudolf Jaenisch
WT-1 is required for early kidney development.
Cell 1993;74(4):679-91.
1993: Moses Rodriguez; A J Dunkel; R L Thiemann; J Leibowitz; M Zijlstra; Rudolf Jaenisch
Abrogation of resistance to Theiler's virus-induced demyelination in H-2b mice deficient in beta 2-microglobulin.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):266-76.
1993: B J Dzamba; H Wu; Rudolf Jaenisch; D M Peters
Fibronectin binding site in type I collagen regulates fibronectin fibril formation.
The Journal of cell biology 1993;121(5):1165-72.
1993: Michael J Grusby; Hugh Auchincloss; R Lee; R S Johnson; J P Spencer; M Zijlstra; Rudolf Jaenisch; V E Papaioannou; Laurie H Glimcher
Mice lacking major histocompatibility complex class I and class II molecules.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):3913-7.
1993: Karen A Hasty; H Wu; M Byrne; M B Goldring; J M Seyer; Rudolf Jaenisch; S M Krane; C L Mainardi
Susceptibility of type I collagen containing mutated alpha 1(1) chains to cleavage by human neutrophil collagenase.
Matrix (Stuttgart, Germany) 1993;13(3):181-6.
1993: W M Strauss; Jessica Dausman; Caroline Beard; C Johnson; J B Lawrence; Rudolf Jaenisch
Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus.
Science (New York, N.Y.) 1993;259(5103):1904-7.
1993: E Li; H M Sucov; K F Lee; R M Evans; Rudolf Jaenisch
Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1590-4.
1993: RW Osorio; Nancy L Ascher; Rudolf Jaenisch; E S Natuzzi; Chris E Freise; John P Roberts; Peter G Stock
Isolation of functional MHC class I-deficient islet cells.
Transplantation proceedings 1993;25(1 Pt 2):968-9.
1993: David A Brenner; L Veloz; Rudolf Jaenisch; J M Alcorn
Stimulation of the collagen alpha 1 (I) endogenous gene and transgene in carbon tetrachloride-induced hepatic fibrosis.
Hepatology (Baltimore, Md.) 1993;17(2):287-92.
1993: Arlene H Sharpe; Rudolf Jaenisch
Retroviral spongiform degenerative disease produced by the murine neurotropic retrovirus Cas-Br-E.
Developments in biological standardization 1993;80():45-52.
1993: En Li; C Beard; Anthony C. Forster; T H Bestor; Rudolf Jaenisch
DNA methylation, genomic imprinting, and mammalian development.
Cold Spring Harbor symposia on quantitative biology 1993;58():297-305.
1992: P Mombaerts; A R Clarke; M A Rudnicki; J Iacomini; Shigeyoshi Itohara; J J Lafaille; L Wang; Y Ichikawa; Rudolf Jaenisch; M L Hooper
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.
Nature 1992;360(6401):225-31.
1992: H Wu; R Fässler; A Schnieke; D Barker; K H Lee; Verne M Chapman; U Francke; Rudolf Jaenisch
An X-linked human collagen transgene escapes X inactivation in a subset of cells.
Development (Cambridge, England) 1992;116(3):687-95.
1992: T Braun; M A Rudnicki; Hans-Henning Arnold; Rudolf Jaenisch
Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death.
Cell 1992;71(3):369-82.
1992: M A Rudnicki; T Braun; S Hinuma; Rudolf Jaenisch
Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development.
Cell 1992;71(3):383-90.
1992: S Hou; Peter C Doherty; M Zijlstra; Rudolf Jaenisch; J M Katz
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1319-25.
1992: N Sanjuan; M Zijlstra; J Carroll; Rudolf Jaenisch; Thomas L Benjamin
Infection by polyomavirus of murine cells deficient in class I major histocompatibility complex expression.
Journal of virology 1992;66(7):4587-90.
1992: E Li; T H Bestor; Rudolf Jaenisch
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.
Cell 1992;69(6):915-26.
1992: K F Lee; E Li; L J Huber; Story C Landis; A H Sharpe; M V Chao; Rudolf Jaenisch
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system.
Cell 1992;69(5):737-49.
1992: M Zijlstra; Hugh Auchincloss; Janet Loring; Catharine M Chase; Paul S Russell; Rudolf Jaenisch
Skin graft rejection by beta 2-microglobulin-deficient mice.
The Journal of experimental medicine 1992;175(4):885-93.
1992: W M Strauss; Rudolf Jaenisch
Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes.
The EMBO journal 1992;11(2):417-22.
1992: I Correa; Mark Bix; N S Liao; M Zijlstra; Rudolf Jaenisch; David H Raulet
Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):653-7.
1992: Pablo Pereira; M Zijlstra; J McMaster; Janet Loring; Rudolf Jaenisch; Susumu Tonegawa
Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice.
The EMBO journal 1992;11(1):25-31.
1992: S M Krane; Rudolf Jaenisch
Site-directed mutagenesis of type I collagen: effect on susceptibility to collagenase.
Matrix (Stuttgart, Germany). Supplement 1992;1():64-7.
1992: W M Strauss; E Jaenisch; Rudolf Jaenisch
A strategy for rapid production and screening of yeast artificial chromosome libraries.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;2(3):150-7.
1991: Thomas Gridley; Rudolf Jaenisch; M Gendron-Maguire
The murine Mov-34 gene: full-length cDNA and genomic organization.
Genomics 1991;11(3):501-7.
1991: D D Barker; H Wu; S Hartung; Michael Breindl; Rudolf Jaenisch
Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice.
Molecular and cellular biology 1991;11(10):5154-63.
1991: M Eichelberger; W Allan; M Zijlstra; Rudolf Jaenisch; Peter C Doherty
Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells.
The Journal of experimental medicine 1991;174(4):875-80.
1991: D Huszar; A Sharpe; S Hashmi; B Bouchard; Alan N Houghton; Rudolf Jaenisch
Generation of pigmented stripes in albino mice by retroviral marking of neural crest melanoblasts.
Development (Cambridge, England) 1991;113(2):653-60.
1991: P W Laird; A Zijderveld; K Linders; M A Rudnicki; Rudolf Jaenisch; Anton Berns
Simplified mammalian DNA isolation procedure.
Nucleic acids research 1991;19(15):4293.
1991: N S Liao; Mark Bix; M Zijlstra; Rudolf Jaenisch; David H Raulet
MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity.
Science (New York, N.Y.) 1991;253(5016):199-202.
1991: T Choi; M Huang; C Gorman; Rudolf Jaenisch
A generic intron increases gene expression in transgenic mice.
Molecular and cellular biology 1991;11(6):3070-4.
1991: R Petersen; S Sobel; C T Wang; Rudolf Jaenisch; Eric Barklis
Cellular transcripts encoded at a locus which permits retrovirus expression in mouse embryonic cells.
Gene 1991;101(2):177-83.
1991: D Huszar; A Sharpe; Rudolf Jaenisch
Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras.
Development (Cambridge, England) 1991;112(1):131-41.
1991: David H Raulet; D M Spencer; Y H Hsiang; Jacki Goldman; Mark Bix; N S Liao; M Zijstra; Rudolf Jaenisch; I Correa
Control of gamma delta T-cell development.
Immunological reviews 1991;120():185-204.
1991: Andre J van Wijnen; T K Choi; Thomas A Owen; K L Wright; Jane B Lian; Rudolf Jaenisch; Janet L Stein; Gary S Stein
Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2573-7.
1991: Mark Bix; N S Liao; M Zijlstra; Janet Loring; Rudolf Jaenisch; David H Raulet
Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice.
Nature 1991;349(6307):329-31.
1991: J J Chun; David G Schatz; M A Oettinger; Rudolf Jaenisch; David Baltimore
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system.
Cell 1991;64(1):189-200.
1991: J S Lee; S Mullaney; R Bronson; A H Sharpe; Rudolf Jaenisch; J Balzarini; E De Clercq; Ruth Ruprecht
Transplacental antiretroviral therapy with 9-(2-phosphonylmethoxyethyl)adenine is embryotoxic in transgenic mice.
Journal of acquired immune deficiency syndromes 1991;4(9):833-8.
1990: Dorothy C Bennett; D Huszar; P J Laipis; Rudolf Jaenisch; I J Jackson
Phenotypic rescue of mutant brown melanocytes by a retrovirus carrying a wild-type tyrosinase-related protein gene.
Development (Cambridge, England) 1990;110(2):471-5.
1990: H Weiher; T Noda; D A Gray; A H Sharpe; Rudolf Jaenisch
Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome.
Cell 1990;62(3):425-34.
1990: H Wu; M H Byrne; A Stacey; M B Goldring; J R Birkhead; Rudolf Jaenisch; Stephen M Krane
Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5888-92.
1990: A H Sharpe; J J Hunter; P Chassler; Rudolf Jaenisch
Role of abortive retroviral infection of neurons in spongiform CNS degeneration.
Nature 1990;346(6280):181-3.
1990: Ruth Ruprecht; A H Sharpe; Rudolf Jaenisch; D Trites
Analysis of 3'-azido-3'-deoxythymidine levels in tissues and milk by isocratic high-performance liquid chromatography.
Journal of chromatography 1990;528(2):371-83.
1990: T Gridley; D A Gray; Terry L. Orr-Weaver; P Soriano; David Barton; U Francke; Rudolf Jaenisch
Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila.
Development (Cambridge, England) 1990;109(1):235-42.
1990: M Zijlstra; Mark Bix; N E Simister; Janet Loring; David H Raulet; Rudolf Jaenisch
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.
Nature 1990;344(6268):742-6.
1990: John F Bateman; T Mascara; W G Cole; A Stacey; Rudolf Jaenisch
The study of collagen structure and function by site-directed mutagenesis of collagen genes.
Annals of the New York Academy of Sciences 1990;580():324-9.
1990: K Harbers; U Francke; P Soriano; Rudolf Jaenisch; U Müller
Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes.
Cytogenetics and cell genetics 1990;53(2-3):129-33.
1989: I Peckham; S Sobel; J Comer; Rudolf Jaenisch; Eric Barklis
Retrovirus activation in embryonal carcinoma cells by cellular promoters.
Genes & development 1989;3(12B):2062-71.
1989: M Zijlstra; E Li; F Sajjadi; S Subramani; Rudolf Jaenisch
Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells.
Nature 1989;342(6248):435-8.
1989: H Stuhlmann; Rudolf Jaenisch; Richard C Mulligan
Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector.
Journal of virology 1989;63(11):4857-65.
1989: K Kratochwil; Klaus von der Mark; E J Kollar; Rudolf Jaenisch; K Mooslehner; M Schwarz; K Haase; I Gmachl; K Harbers
Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner.
Cell 1989;57(5):807-16.
1989: S J Compere; P Baldacci; A H Sharpe; T Thompson; H Land; Rudolf Jaenisch
The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2224-8.
1989: A H Sharpe; J J Hunter; Ruth Ruprecht; Rudolf Jaenisch
Maternal transmission of retroviral disease and strategies for preventing infection of the neonate.
Journal of virology 1989;63(3):1049-53.
1989: H Stuhlmann; Rudolf Jaenisch; Richard C Mulligan
Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance.
Molecular and cellular biology 1989;9(1):100-8.
1989: W G Cole; Rudolf Jaenisch; John F Bateman
New insights into the molecular pathology of osteogenesis imperfecta.
The Quarterly journal of medicine 1989;70(261):1-4.
1989: S J Compere; P A Baldacci; A H Sharpe; Rudolf Jaenisch
Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia.
Molecular and cellular biology 1989;9(1):6-14.
1989: John F Bateman; T Mascara; W G Cole; A Stacey; Rudolf Jaenisch
Collagen protein abnormalities produced by site-directed mutagenesis of the pro alpha 1(I) gene.
Connective tissue research 1989;20(1-4):205-12; discussion 261-3.
1988: A H Sharpe; J J Hunter; Ruth Ruprecht; Rudolf Jaenisch
Maternal transmission of retroviral disease: transgenic mice as a rapid test system for evaluating perinatal and transplacental antiretroviral therapy.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9792-6.
1988: S J Compere; P Baldacci; Rudolf Jaenisch
Oncogenes in transgenic mice.
Biochimica et biophysica acta 1988;948(2):129-49.
1988: Gerard Tromp; Helena Kuivaniemi; A Stacey; H Shikata; C T Baldwin; Rudolf Jaenisch; Darwin J Prockop
Structure of a full-length cDNA clone for the prepro alpha 1(I) chain of human type I procollagen.
The Biochemical journal 1988;253(3):919-22.
1988: P J Wettstein; M P Colombo; Rudolf Jaenisch
Non-H-2 histocompatibility antigens encoded by Moloney-murine leukemia virus in Mov mouse strains are detectable by skin grafting and cytolytic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(12):4337-41.
1988: Rudolf Jaenisch
Transgenic animals.
Science (New York, N.Y.) 1988;240(4858):1468-74.
1988: A Stacey; J Bateman; T Choi; T Mascara; W Cole; Rudolf Jaenisch
Perinatal lethal osteogenesis imperfecta in transgenic mice bearing an engineered mutant pro-alpha 1(I) collagen gene.
Nature 1988;332(6160):131-6.
1987: T Berleth; P Nobis; Rudolf Jaenisch; K Harbers
Activation of endogenous retroviral genomes in Mov strains of mice.
The Journal of general virology 1987;68 ( Pt 11)():2919-23.
1987: P Soriano; E A Keitges; D F Schorderet; K Harbers; Stanley M Gartler; Rudolf Jaenisch
High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7218-20.
1987: H Weiher; Eric Barklis; W Ostertag; Rudolf Jaenisch
Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells.
Journal of virology 1987;61(9):2742-6.
1987: A Stacey; R Mulligan; Rudolf Jaenisch
Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells.
Journal of virology 1987;61(8):2549-54.
1987: A H Sharpe; Rudolf Jaenisch; Ruth Ruprecht
Retroviruses and mouse embryos: a rapid model for neurovirulence and transplacental antiviral therapy.
Science (New York, N.Y.) 1987;236(4809):1671-4.
1987: M Dziadek; R Timpl; Rudolf Jaenisch
Collagen synthesis by cell lines derived from Mov-13 mouse embryos which have a lethal mutation in the collagen alpha 1(I) gene.
The Biochemical journal 1987;244(2):375-9.
1987: P Soriano; T Gridley; Rudolf Jaenisch
Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death.
Genes & development 1987;1(4):366-75.
1987: A Schnieke; M Dziadek; J Bateman; T Mascara; K Harbers; R Gelinas; Rudolf Jaenisch
Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(3):764-8.
1987: H Rohdewohld; H Weiher; Wolf Reik; Rudolf Jaenisch; M Breindl
Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites.
Journal of virology 1987;61(2):336-43.
1987: M P Colombo; Rudolf Jaenisch; P J Wettstein
Endogenous retroviruses lead to the expression of a histocompatibility antigen detectable by skin graft rejection.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(1):189-93.
1986: K Harbers; P Soriano; U Müller; Rudolf Jaenisch
High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse.
Nature 1986;324(6098):682-5.
1986: P Soriano; R D Cone; R C Mulligan; Rudolf Jaenisch
Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses.
Science (New York, N.Y.) 1986;234(4782):1409-13.
1986: Eric Barklis; R C Mulligan; Rudolf Jaenisch
Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells.
Cell 1986;47(3):391-9.
1986: K Kratochwil; M Dziadek; J Löhler; K Harbers; Rudolf Jaenisch
Normal epithelial branching morphogenesis in the absence of collagen I.
Developmental biology 1986;117(2):596-606.
1986: P Soriano; Rudolf Jaenisch
Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages.
Cell 1986;46(1):19-29.
1986: S Hartung; Rudolf Jaenisch; Michael Breindl
Retrovirus insertion inactivates mouse alpha 1(I) collagen gene by blocking initiation of transcription.
Nature 1986;320(6060):365-7.
1986: M Münke; K Harbers; Rudolf Jaenisch; U Francke
Chromosomal mapping of four different integration sites of Moloney murine leukemia virus including the locus for alpha 1(I) collagen in mouse.
Cytogenetics and cell genetics 1986;43(3-4):140-9.
1986: Rudolf Jaenisch; P Soriano
Retroviruses as tools for mammalian development.
Symposium on Fundamental Cancer Research 1986;39():59-65.
1985: Rudolf Jaenisch
Mammalian neural crest cells participate in normal embryonic development on microinjection into post-implantation mouse embryos.
Nature 1985;318(6042):181-3.
1985: D Jähner; K Haase; R Mulligan; Rudolf Jaenisch
Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):6927-31.
1985: D Jähner; Rudolf Jaenisch
Chromosomal position and specific demethylation in enhancer sequences of germ line-transmitted retroviral genomes during mouse development.
Molecular and cellular biology 1985;5(9):2212-20.
1985: D Jähner; Rudolf Jaenisch
Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity.
Nature 1985;315(6020):594-7.
1985: Rudolf Jaenisch; A Schnieke; K Harbers
Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(5):1451-5.
1985: Wolf Reik; H Weiher; Rudolf Jaenisch
Replication-competent Moloney murine leukemia virus carrying a bacterial suppressor tRNA gene: selective cloning of proviral and flanking host sequences.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(4):1141-5.
1985: Rudolf Jaenisch; Michael Breindl; K Harbers; D Jähner; Jürgen Löhler
Retroviruses and insertional mutagenesis.
Cold Spring Harbor symposia on quantitative biology 1985;50():439-45.
1984: H Stuhlmann; R Cone; R C Mulligan; Rudolf Jaenisch
Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(22):7151-5.
1984: J Löhler; R Timpl; Rudolf Jaenisch
Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death.
Cell 1984;38(2):597-607.
1984: Michael Breindl; K Harbers; Rudolf Jaenisch
Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure.
Cell 1984;38(1):9-16.
1984: Rudolf Jaenisch; D Jähner
Methylation, expression and chromosomal position of genes in mammals.
Biochimica et biophysica acta 1984;782(1):1-9.
1984: K Harbers; M Kuehn; H Delius; Rudolf Jaenisch
Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(5):1504-8.
1983: C Stewart; K Harbers; D Jähner; Rudolf Jaenisch
X chromosome-linked transmission and expression of retroviral genomes microinjected into mouse zygotes.
Science (New York, N.Y.) 1983;221(4612):760-2.
1983: A Schnieke; K Harbers; Rudolf Jaenisch
Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene.
Nature 1983;304(5924):315-20.
1983: D Simon; H Stuhlmann; D Jähner; H Wagner; E Werner; Rudolf Jaenisch
Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious.
Nature 1983;304(5923):275-7.
1983: M Breindl; H Kalthoff; Rudolf Jaenisch
Transcription of cloned Moloney murine leukemia proviral DNA injected into Xenopus laevis oocytes.
Nucleic acids research 1983;11(12):3989-4006.
1983: A Schnieke; H Stuhlmann; K Harbers; I Chumakov; Rudolf Jaenisch
Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.
Journal of virology 1983;45(2):505-13.
1983: Rudolf Jaenisch; K Harbers; D Jähner; C Stewart; H Stuhlmann
Expression of retroviruses during early mouse embryogenesis.
Haematology and blood transfusion 1983;28():270-4.
1983: Rudolf Jaenisch; K Harbers; A Schnieke; Jürgen Löhler; I Chumakov; D Jähner; D Grotkopp; E Hoffmann
Germline integration of moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death.
Cell 1983;32(1):209-16.
1983: D Jähner; C L Stewart; H Stuhlmann; K Harbers; Rudolf Jaenisch
Retroviruses and embryogenesis: de novo methylation activity involved in gene expression.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 2():611-9.
1983: Rudolf Jaenisch
Retroviruses and mouse embryos: a model system in which to study gene expression in development and differentiation.
Ciba Foundation symposium 1983;98():44-62.
1983: Rudolf Jaenisch
Endogenous retroviruses.
Cell 1983;32(1):5-6.
1982: Rudolf Jaenisch
Retroviruses and embryogenesis, Seventh Adolf Butenandt Lecture given to the Gesellschaft für Biologische Chemie in Damp 2000 on September 29, 1982.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1982;363(11):1267-71.
1982: D Jähner; H Stuhlmann; C L Stewart; K Harbers; Jürgen Löhler; I Simon; Rudolf Jaenisch
De novo methylation and expression of retroviral genomes during mouse embryogenesis.
Nature 1982;298(5875):623-8.
1982: I Simon; J Löhler; Rudolf Jaenisch
Virus-specific transcription and translation in organs of BALB/Mo mice: comparative study using quantitative hybridization, in situ hybridization, and immunocytochemistry.
Virology 1982;120(1):106-21.
1982: C L Stewart; H Stuhlmann; D Jähner; Rudolf Jaenisch
De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(13):4098-102.
1982: I Chumakov; H Stuhlmann; K Harbers; Rudolf Jaenisch
Cloning of two genetically transmitted Moloney leukemia proviral genomes: correlation between biological activity of the cloned DNA and viral genome activation in the animal.
Journal of virology 1982;42(3):1088-98.
1982: Michael Breindl; U Nath; D Jähner; Rudolf Jaenisch
DNase I sensitivity of endogenous and exogenous proviral genome copies in M-MuLV-induced tumors of Mov-3 Mice.
Virology 1982;119(1):204-8.
1982: K Harbers; A Schnieke; H Stuhlmann; Rudolf Jaenisch
Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes.
Nucleic acids research 1982;10(8):2521-37.
1982: W Fiedler; P Nobis; D Jähner; Rudolf Jaenisch
Differentiation and virus expression in BALB/Mo mice: endogenous Moloney leukemia virus is not activated in hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(6):1874-8.
1982: Rudolf Jaenisch; K Harbers; D Jähner; C Stewart; H Stuhlmann
DNA methylation, retroviruses, and embryogenesis.
Journal of cellular biochemistry 1982;20(4):331-6.
1981: K Harbers; A Schnieke; H Stuhlmann; D Jähner; Rudolf Jaenisch
DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(12):7609-13.
1981: K Harbers; D Jähner; Rudolf Jaenisch
Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal.
Nature 1981;293(5833):540-2.
1981: H Stuhlmann; D Jähner; Rudolf Jaenisch
Infectivity and methylation of retroviral genomes is correlated with expression in the animal.
Cell 1981;26(2 Pt 2):221-32.
1981: J S Greenberger; R K Shadduck; Rudolf Jaenisch; A Waheed; M A Sakakeeny
Effects of murine leukemia virus infection on long-term hematopoiesis in vitro emphasized by increased survival of bone marrow cultures derived from BALB/Mo mice.
Cancer research 1981;41(9 Pt 1):3556-65.
1981: Rudolf Jaenisch; D Jähner; P Nobis; I Simon; Jürgen Löhler; K Harbers; D Grotkopp
Chromosomal position and activation of retroviral genomes inserted into the germ line of mice.
Cell 1981;24(2):519-29.
1980: D Jähner; Rudolf Jaenisch
Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation.
Nature 1980;287(5781):456-8.
1980: P Nobis; Rudolf Jaenisch
Passive immunotherapy prevents expression of endogenous Moloney virus and amplification of proviral DNA in BALB/Mo mice.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(6):3677-81.
1980: M Breindl; Lee Bacheler; H Fan; Rudolf Jaenisch
Chromatin conformation of integrated Moloney leukemia virus DNA sequences in tissues of BALB/Mo mice and in virus-infected cell lines.
Journal of virology 1980;34(2):373-82.
1980: Rudolf Jaenisch
[Genetic inheritance of tumor viruses].
Monatsschrift für Kinderheilkunde 1980;128(5):230-1.
1980: D Jähner; H Stuhlmann; Rudolf Jaenisch
Conformation of free and of integrated Moloney leukemia virus proviral DNA in preleukemic and leukemic BALB/Mo mice.
Virology 1980;101(1):111-23.
1980: Rudolf Jaenisch
Retroviruses and embryogenesis: microinjection of Moloney leukemia virus into midgestation mouse embryos.
Cell 1980;19(1):181-8.
1979: Rudolf Jaenisch; E Hoffmann
Transcription of endogenous C-type viruses in resting and proliferating tissues of BALB/Mo mice.
Virology 1979;98(2):289-97.
1979: H van der Putten; E Terwindt; A Berns; Rudolf Jaenisch
The integration sites of endogenous and exogenous Moloney murine leukemia virus.
Cell 1979;18(1):109-16.
1979: M Breindl; J Doehmer; K Willecke; J Dausman; Rudolf Jaenisch
Germ line integration of Moloney leukemia virus: identification of the chromosomal integration site.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(4):1938-42.
1979: Lee Bacheler; Rudolf Jaenisch; H Fan
Highly inducible cell lines derived from mice genetically transmitting the Moloney murine leukemia virus genome.
Journal of virology 1979;29(3):899-906.
1979: Rudolf Jaenisch
Moloney leukemia virus gene expression and gene amplification in preleukemic and leukemic BALB/Mo mice.
Virology 1979;93(1):80-90.
1979: M Breindl; Rudolf Jaenisch
Conformation of Moloney murine leukaemia proviral sequences in chromatin from leukaemic and nonleukaemic cells.
Nature 1979;277(5694):320-2.
1979: J Doehmer; M Breindl; K Willecke; Rudolf Jaenisch
Genetic transmission of Moloney leukemia virus: mapping of the chromosomal integration site.
Haematology and blood transfusion 1979;23():561-8.
1978: H Fan; Rudolf Jaenisch; P MacIsaac
Low-multiplicity infection of Moloney murine leukemia virus in mouse cells: effect on number of viral DNA copies and virus production in producer cells.
Journal of virology 1978;28(3):802-9.
1977: Rudolf Jaenisch
Germ line integration of moloney leukemia virus: effect of homozygosity at the m-mulV locus.
Cell 1977;12(3):691-6.
1977: M Strand; Thomas August; Rudolf Jaenisch
Oncornavirus gene expression during embryonal development of the mouse.
Virology 1977;76(2):886-90.
1976: A Berns; Rudolf Jaenisch
Increase of AKR-specific sequences in tumor tissues of leukemic AKR mice.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(7):2448-52.
1976: Rudolf Jaenisch
Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(4):1260-4.
1976: Rudolf Jaenisch; J Dausman; V Cox; H Fan
Infection of developing mouse embryos with murine leukemia virus: tissue specificity and genetic transmission of the virus.
Hämatologie und Bluttransfusion 1976;19():341-56.
1975: Rudolf Jaenisch; H Fan; B Croker
Infection of preimplantation mouse embryos and of newborn mice with leukemia virus: tissue distribution of viral DNA and RNA and leukemogenesis in the adult animal.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(10):4008-12.
1975: Rudolf Jaenisch
Infection of mouse blastocysts with SV40 DNA: normal development of the infected embryos and persistence of SV40-specific DNA sequences in the adult animals.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 1():375-80.
1974: Rudolf Jaenisch; B Mintz
Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1250-4.
1973: E Jacob; Rudolf Jaenisch; P H Hofschneider
Replication of the single-stranded DNA bacteriophage M 13. On the transcription in vivo of the M 13 replicative-form DNA.
European journal of biochemistry / FEBS 1973;32(3):432-43.
1973: Rudolf Jaenisch; Arnold J Levine
DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers.
Journal of molecular biology 1973;73(2):199-212.
1972: Rudolf Jaenisch; Arnold J Levine
DNA replication in SV40-infected cells. VI. The effect of cycloheximide on the formation of SV40 oligomeric DNA.
Virology 1972;48(2):373-9.
1972: D R Dubbs; S Kit; Rudolf Jaenisch; Arnold J Levine
Isolation of simian virus 40 recombinants from cells infected with oligomeric forms of simian virus 40 deoxyribonucleic acid.
Journal of virology 1972;9(4):717-9.
1972: Rudolf Jaenisch
Evidence for SV40 specific RNA containing virus and host specific sequences.
Nature: New biology 1972;235(54):46-7.
1971: Rudolf Jaenisch; Arnold J Levine
Infection of primary African green monkey cells with SV40 monomeric and dimeric DNA.
Journal of molecular biology 1971;61(3):735-8.
1971: Rudolf Jaenisch; A Mayer; Arnold J Levine
Replicating SV40 molecules containing closed circular template DNA strands.
Nature: New biology 1971;233(37):72-5.
1971: Rudolf Jaenisch; Arnold J Levine
DNA replication in SV40-infected cells. V. Circular and catenated oligomers of SV40 DNA.
Virology 1971;44(3):480-93.
1970: Rudolf Jaenisch; E Jacob; P H Hofschneider
Replication of the small coliphage M13: evidence for long-living M13 specific messenger RNA.
Nature 1970;227(5253):59-60.
1969: Rudolf Jaenisch; P H Hofschneider; A Preuss
Isolation of circular DNA by zonal centrifugation. Separation of normallength, double length and catenated M13 replicative form DNA and of host specific "episomal" DNA.
Biochimica et biophysica acta 1969;190(1):88-100.
1966: Rudolf Jaenisch; P H Hofschneider; A Preuss
Uber infektiöse Substrukturen aus Escherichia coli Bakteriophagen. VIII. On the tertiary structure and biological properties of phiX174 replicative form.
Journal of molecular biology 1966;21(3):501-16.
1966: R Benzinger; Rudolf Jaenisch; P H Hofschneider
Uber infektiöse Substrukturen aus Bakteriophagen. VI. A simple method for separating the replicative form from single-stranded phiX174 DNA.
Journal of molecular biology 1966;21(3):493-9.