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Frederic Jaisser

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Pia Jeggle; Hans Oberleithner; Antoine Tarjus; Chiara Callies; Celine Fassot; Johannes Fels; Frederic Jaisser; Kristina Kusche-Vihrog
Epithelial sodium channel stiffens the vascular endothelium in vitro and in liddle mice.
Smail Messaoudi; Antoine Ouvrard-Pascaud; Véronique Pelloux; Janelise Samuel; Catalina Sierra-Ramos; Antoine Tarjus; Diego Alvarez de la Rosa; Karine Clément; Claude Delcayre; Nicolette Farman; Basile Gravez; Jean-Marie Launay; Frederic Jaisser
Aldosterone-specific activation of cardiomyocyte mineralocorticoid receptor in vivo.
Celine Latouche; Natalia López Andrés; Smail Messaoudi; Claudine Perret; Patrick Rossignol; Faiez Zannad; Aurélie Nguyen Dinh Cat; Diego Alvarez de la Rosa; Soumaya El Moghrabi; Nicolette Farman; Ivan Hernandez-Diaz; Frederic Jaisser
Neutrophil gelatinase-associated lipocalin is a novel mineralocorticoid target in the cardiovascular system.

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All Publications

2013: Pia Jeggle; Hans Oberleithner; Antoine Tarjus; Chiara Callies; Celine Fassot; Johannes Fels; Frederic Jaisser; Kristina Kusche-Vihrog
Epithelial sodium channel stiffens the vascular endothelium in vitro and in liddle mice.
Hypertension 2013;61(5):1053-9.
2013: Smail Messaoudi; Antoine Ouvrard-Pascaud; Véronique Pelloux; Janelise Samuel; Catalina Sierra-Ramos; Antoine Tarjus; Diego Alvarez de la Rosa; Karine Clément; Claude Delcayre; Nicolette Farman; Basile Gravez; Jean-Marie Launay; Frederic Jaisser
Aldosterone-specific activation of cardiomyocyte mineralocorticoid receptor in vivo.
Hypertension 2013;61(2):361-7.
2012: Celine Latouche; Natalia López Andrés; Smail Messaoudi; Claudine Perret; Patrick Rossignol; Faiez Zannad; Aurélie Nguyen Dinh Cat; Diego Alvarez de la Rosa; Soumaya El Moghrabi; Nicolette Farman; Ivan Hernandez-Diaz; Frederic Jaisser
Neutrophil gelatinase-associated lipocalin is a novel mineralocorticoid target in the cardiovascular system.
Hypertension 2012;59(5):966-72.
2012: Smail Messaoudi; Feriel Azibani; Claude Delcayre; Frederic Jaisser
Aldosterone, mineralocorticoid receptor, and heart failure.
Molecular and cellular endocrinology 2012;350(2):266-72.
2012: Aurelie Nguyen Dinh Cat; Frederic Jaisser
Extrarenal effects of aldosterone.
Current opinion in nephrology and hypertension 2012;21(2):147-56.
2012: Finn Gustafsson; Frederic Jaisser; Michel Azizi; Johann Bauersachs; Patrick Rossignol
Targeting the aldosterone pathway in cardiovascular disease.
Fundamental & clinical pharmacology 2012;26(1):135-45.
2012: Elodie Bousquet; Yvonne de Kozak; Nicolette Farman; Brigitte Goldenberg; Frederic Jaisser; Laurent Jonet; Guillaume Leroux Les Jardins; André Ly; Marie-Christine Naud; Min Zhao; Bernadette Besson-Lescure; Francine Behar-Cohen
The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis.
PloS one 2012;7(11):e49036.
2012: Aurelie Nguyen Dinh Cat; Trenton Schoeb; David G Warnock; Vincent Agrapart; Brigitte Escoubet; Wenguang Feng; Violaine Griol-Charhbili; Edgar Jaimes; Frederic Jaisser
Cardiomyopathy and response to enzyme replacement therapy in a male mouse model for Fabry disease.
PloS one 2012;7(5):e33743.
2012: Smail Messaoudi; Junichi Sadoshima; An Di Zhang; Brigitte Escoubet; Nicolette Farman; Violaine Griol-Charhbili; Frederic Jaisser
The epidermal growth factor receptor is involved in angiotensin II but not aldosterone/salt-induced cardiac remodelling.
PloS one 2012;7(1):e30156.
2011: Min Zhao; Elodie Bousquet; Nicolette Farman; Frederic Jaisser; Jean-Claude Jeanny; Fatemeh Valamanesh; Francine Behar-Cohen
Differential regulations of AQP4 and Kir4.1 by triamcinolone acetonide and dexamethasone in the healthy and inflamed retina.
Investigative ophthalmology & visual science 2011;52(9):6340-7.
2011: Jean-Philippe Bertocchio; Frederic Jaisser
[Aldosterone and kidney diseases: an emergent paradigm with important clinical implications].
Néphrologie & thérapeutique 2011;7(3):139-47.
2011: Jean-Philippe Bertocchio; David G Warnock; Frederic Jaisser
Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease.
Kidney international 2011;79(10):1051-60.
2011: Frederic Jaisser; Bernard Swynghedauw; Claude Delcayre
The mineralocorticoid receptor in heart: different effects in different cells.
Hypertension 2011;57(4):679-80.
2011: Violaine Griol-Charhbili; Céline Fassot; Smail Messaoudi; Claudine Perret; Vincent Agrapart; Frederic Jaisser
Epidermal growth factor receptor mediates the vascular dysfunction but not the remodeling induced by aldosterone/salt.
Hypertension 2011;57(2):238-44.
2010: Celine Latouche; Yannis Sainte-Marie; Marja Steenman; Paulo Castro-Chaves; Aniko Naray-Fejes-Toth; Geza Fejes-Toth; Nicolette Farman; Frederic Jaisser
Molecular signature of mineralocorticoid receptor signaling in cardiomyocytes: from cultured cells to mouse heart.
Endocrinology 2010;151(9):4467-76.
2010: Min Zhao; Fatemeh Valamanesh; Isabelle Celerier; Michèle Savoldelli; Laurent Jonet; Jean-Claude Jeanny; Frederic Jaisser; Nicolette Farman; Francine Behar-Cohen
The neuroretina is a novel mineralocorticoid target: aldosterone up-regulates ion and water channels in Müller glial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(9):3405-15.
2010: Iván Hernández-Díaz; Teresa Giraldez; María Rosa Arnau; Veronique A J Smits; Frederic Jaisser; Nicolette Farman; Diego Alvarez de la Rosa
The mineralocorticoid receptor is a constitutive nuclear factor in cardiomyocytes due to hyperactive nuclear localization signals.
Endocrinology 2010;151(8):3888-99.
2010: Aurelie Nguyen Dinh Cat; Violaine Griol-Charhbili; Laurent Loufrani; carlos labat; Laura Benjamin; Nicolette Farman; Patrick Lacolley; Daniel Henrion; Frederic Jaisser
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(7):2454-63.
2010: Nicolette Farman; Eve Maubec; Burkhard Poeggeler; Jennifer E Klatte; Frederic Jaisser; Ralf Paus
The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?
Experimental dermatology 2010;19(2):100-7.
2009: Tim Ziera; Horst Irlbacher; Anja Fromm; Celine Latouche; Susanne M Krug; Michael Fromm; Frederic Jaisser; Steffen A Borden
Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(11):3936-46.
2009: Aurélie Nguyen Dinh Cat; Antoine Ouvrard-Pascaud; François Tronche; Maud Clemessy; daniel gonzalez-nunez; Nicolette Farman; Frederic Jaisser
Conditional transgenic mice for studying the role of the glucocorticoid receptor in the renal collecting duct.
Endocrinology 2009;150(5):2202-10.
2009: Ana Gomez; Angélica Rueda; Yannis Sainte-Marie; Laetitia Pereira; Spyros Zissimopoulos; Xinsheng Zhu; Roxane Schaub; Emeline Perrier; Romain Perrier; Céline Latouche; Sylvain Richard; Marie-Christine Picot; Frederic Jaisser; F Anthony Lai; Héctor H Valdivia; Jean-Pierre Benitah
Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins.
Circulation 2009;119(16):2179-87.
2009: G Palais; A Nguyen Dinh Cat; H Friedman; N Panek-Huet; A Millet; F Tronche; B Gellen; Jean-Jacques Mercadier; Alan Peterson; Frederic Jaisser
Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system.
Physiological genomics 2009;37(2):140-6.
2008: An Di Zhang; Aurelie Nguyen Dinh Cat; Christelle Soukaseum; Brigitte Escoubet; Aïcha Cherfa; Smail Messaoudi; Claude Delcayre; Jane-Lise Samuel; Frederic Jaisser
Cross-talk between mineralocorticoid and angiotensin II signaling for cardiac remodeling.
Hypertension 2008;52(6):1060-7.
2008: Olivier Duverger; Delia Lee; Mohammad Q Hassan; Susie X Chen; Frederic Jaisser; Jane B Lian; Maria I Morasso
Molecular consequences of a frameshifted DLX3 mutant leading to Tricho-Dento-Osseous syndrome.
The Journal of biological chemistry 2008;283(29):20198-208.
2007: Yannis Sainte-Marie; Aurelie Nguyen Dinh Cat; Romain Perrier; Laurence Mangin; Christelle Soukaseum; Michel Peuchmaur; François Tronche; Nicolette Farman; Brigitte Escoubet; Jean-Pierre Benitah; Frederic Jaisser
Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3133-41.
2007: Yannis Sainte-Marie; Antoine Toulon; Ralf Paus; Eve Maubec; Aicha Cherfa; Maggy Grossin; Vincent Descamps; Maud Clemessy; Jean-Marie Gasc; Michel Peuchmaur; Adam Glick; Nicolette Farman; Frederic Jaisser
Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.
The American journal of pathology 2007;171(3):846-60.
2007: A Nguyen Din Cat; Yannis Sainte-Marie; Frederic Jaisser
Animal models in cardiovascular diseases: new insights from conditional models.
Handbook of experimental pharmacology 2007;(178):377-405.
2005: Romain Perrier; Sylvain Richard; Yannis Sainte-Marie; Bernard C Rossier; Frederic Jaisser; Edith Hummler; Jean-Pierre Benitah
A direct relationship between plasma aldosterone and cardiac L-type Ca2+ current in mice.
The Journal of physiology 2005;569(Pt 1):153-62.
2005: Antoine Ouvrard-Pascaud; Yannis Sainte-Marie; Jean-Pierre Benitah; Romain Perrier; Christelle Soukaseum; Aurelie Nguyen Dinh Cat; Anne Royer; Khai Le Quang; Flavien Charpentier; Sophie Demolombe; Fatima Mechta-Grigoriou; Ahmed T Beggah; Pierre Maison-Blanche; Marie-Edith Oblin; Claude Delcayre; Glenn I Fishman; Nicolette Farman; Brigitte Escoubet; Frederic Jaisser
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias.
Circulation 2005;111(23):3025-33.
2005: Stefania Puttini; Antoine Ouvrard-Pascaud; Gael Palais; Ahmed T Beggah; Philippe Gascard; Michel Cohen-Tannoudji; Charles Babinet; Marcel Blot-Chabaud; Frederic Jaisser
Development of a targeted transgenesis strategy in highly differentiated cells: a powerful tool for functional genomic analysis.
Journal of biotechnology 2005;116(2):145-51.
2004: Cathy Le Moëllic; Antoine Ouvrard-Pascaud; Claudia Capurro; Françoise Cluzeaud; Michèle Fay; Frederic Jaisser; Nicolette Farman; Marcel Blot-Chabaud
Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.
Journal of the American Society of Nephrology : JASN 2004;15(5):1145-60.
2004: Antoine Ouvrard-Pascaud; Stefania Puttini; Yannis Sainte-Marie; Rafika Athman; Virginie Fontaine; Françoise Cluzeaud; Nicolette Farman; Marie-Edith Rafestin-Oblin; Marcel Blot-Chabaud; Frederic Jaisser
Conditional gene expression in renal collecting duct epithelial cells: use of the inducible Cre-lox system.
American journal of physiology. Renal physiology 2004;286(1):F180-7.
2003: Antoine Ouvrard-Pascaud; Frederic Jaisser
Pathophysiological role of the mineralocorticoid receptor in heart: analysis of conditional transgenic models.
Pflügers Archiv : European journal of physiology 2003;445(4):477-81.
2002: Sheerazed Boulkroun; Michèle Fay; Maria-Christina Zennaro; Brigitte Escoubet; Frederic Jaisser; Marcel Blot-Chabaud; Nicolette Farman; Nathalie Courtois-Coutry
Characterization of rat NDRG2 (N-Myc downstream regulated gene 2), a novel early mineralocorticoid-specific induced gene.
The Journal of biological chemistry 2002;277(35):31506-15.
2002: Ahmed T Beggah; Brigitte Escoubet; Stefania Puttini; Stephane Cailmail; Vanessa Delage; Antoine Ouvrard-Pascaud; Brigitte Bocchi; Michel Peuchmaur; Claude Delcayre; Nicolette Farman; Frederic Jaisser
Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7160-5.
2001: Stefania Puttini; Ahmed T Beggah; Antoine Ouvrard-Pascaud; C Legris; Marcel Blot-Chabaud; Nicolette Farman; Frederic Jaisser
Tetracycline-inducible gene expression in cultured rat renal CD cells and in intact CD from transgenic mice.
American journal of physiology. Renal physiology 2001;281(6):F1164-72.
1999: Evelyne Ferrary; Michel Cohen-Tannoudji; G Pehau-Arnaudet; A Lapillonne; Rafika Athman; T Ruiz; L Boulouha; Fatima el-Marjou; A Doye; JJ Fontaine; Claude Antony; Charles Babinet; Daniel Louvard; Frederic Jaisser; Sylvie Robine
In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush borders.
The Journal of cell biology 1999;146(4):819-30.
1999: Marc Cougnon; P Bouyer; Frederic Jaisser; Aleksander Edelman; Gabrielle Planelles
Ammonium transport by the colonic H(+)-K(+)-ATPase expressed in Xenopus oocytes.
The American journal of physiology 1999;277(2 Pt 1):C280-7.
1999: Frederic Jaisser; Ahmed T Beggah
The nongastric H+-K+-ATPases: molecular and functional properties.
The American journal of physiology 1999;276(6 Pt 2):F812-24.
1999: Daniel Pinto; Sylvie Robine; Frederic Jaisser; Fatima el-Marjou; Daniel Louvard
Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines.
The Journal of biological chemistry 1999;274(10):6476-82.
1998: Frederic Jaisser; Ahmed T Beggah
Transgenic models in renal tubular physiology.
Experimental nephrology 1998;6(5):438-46.
1998: Marc Cougnon; P Bouyer; Gabrielle Planelles; Frederic Jaisser
Does the colonic H,K-ATPase also act as an Na,K-ATPase?
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6516-20.
1998: Michel Cohen-Tannoudji; Sylvie Robine; A Choulika; Daniel Pinto; Fatima el-Marjou; Charles Babinet; Daniel Louvard; Frederic Jaisser
I-SceI-induced gene replacement at a natural locus in embryonic stem cells.
Molecular and cellular biology 1998;18(3):1444-8.
1997: Sylvie Robine; Frederic Jaisser; Daniel Louvard
Epithelial cell growth and differentiation. IV. Controlled spatiotemporal expression of transgenes: new tools to study normal and pathological states.
The American journal of physiology 1997;273(4 Pt 1):G759-62.
1996: Marc Cougnon; Gabrielle Planelles; M S Crowson; Gary E Shull; Bernard C Rossier; Frederic Jaisser
The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase.
The Journal of biological chemistry 1996;271(13):7277-80.
1996: X Wang; Frederic Jaisser; Jean-Daniel Horisberger
Role in cation translocation of the N-terminus of the alpha-subunit of the Na(+)-K+ pump of Bufo.
The Journal of physiology 1996;491 ( Pt 3)():579-94.
1996: Frederic Jaisser; Brigitte Escoubet; N Coutry; E Eugene; Jean-Pierre Bonvalet; Nicolette Farman
Differential regulation of putative K(+)-ATPase by low-K+ diet and corticosteroids in rat distal colon and kidney.
The American journal of physiology 1996;270(2 Pt 1):C679-87.
1996: Frederic Jaisser
[Molecular and functional diversity of NA,K-ATPase and renal H,K-ATPases].
Néphrologie 1996;17(7):401-8.
1995: Paul Mathews; Dirk Claeys; Frederic Jaisser; Käthi Geering; Jean-Daniel Horisberger; J P Kraehenbuhl; Bernard C Rossier
Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase.
The American journal of physiology 1995;268(5 Pt 1):C1207-14.
1994: P Beguin; Ahmed T Beggah; A V Chibalin; P Burgener-Kairuz; Frederic Jaisser; Paul Mathews; Bernard C Rossier; Susanna Cotecchia; Käthi Geering
Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells. Identification of a novel motif for PKC-mediated phosphorylation.
The Journal of biological chemistry 1994;269(39):24437-45.
1994: Frederic Jaisser; P Jaunin; Käthi Geering; Bernard C Rossier; Jean-Daniel Horisberger
Modulation of the Na,K-pump function by beta subunit isoforms.
The Journal of general physiology 1994;103(4):605-23.
1993: P Jaunin; Frederic Jaisser; Ahmed T Beggah; K Takeyasu; P Mangeat; Bernard C Rossier; Jean-Daniel Horisberger; Käthi Geering
Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps.
The Journal of cell biology 1993;123(6 Pt 2):1751-9.
1993: Frederic Jaisser; Jean-Daniel Horisberger; Käthi Geering; Bernard C Rossier
Mechanisms of urinary K+ and H+ excretion: primary structure and functional expression of a novel H,K-ATPase.
The Journal of cell biology 1993;123(6 Pt 1):1421-9.
1993: Frederic Jaisser; Jean-Daniel Horisberger; Bernard C Rossier
Primary sequence and functional expression of a novel beta subunit of the P-ATPase gene family.
Pflügers Archiv : European journal of physiology 1993;425(5-6):446-52.
1993: Käthi Geering; P Jaunin; Frederic Jaisser; A M Mérillat; Jean-Daniel Horisberger; Paul Mathews; V Lemas; Douglas Fambrough; Bernard C Rossier
Mutation of a conserved proline residue in the beta-subunit ectodomain prevents Na(+)-K(+)-ATPase oligomerization.
The American journal of physiology 1993;265(4 Pt 1):C1169-74.
1993: Frederic Jaisser; N Coutry; Nicolette Farman; H J Binder; Bernard C Rossier
A putative H(+)-K(+)-ATPase is selectively expressed in surface epithelial cells of rat distal colon.
The American journal of physiology 1993;265(4 Pt 1):C1080-9.
1992: Frederic Jaisser; Jean-Daniel Horisberger; Bernard C Rossier
The beta subunit modulates potassium activation of the Na-K pump.
Annals of the New York Academy of Sciences 1992;671():113-9.
1992: Frederic Jaisser; Cecilia M Canessa; Jean-Daniel Horisberger; Bernard C Rossier
Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase. The beta subunit modulates potassium activation of the Na,K-pump.
The Journal of biological chemistry 1992;267(24):16895-903.
1990: Marcel Blot-Chabaud; Frederic Jaisser; Jean-Pierre Bonvalet; Nicolette Farman
Effect of cell sodium on Na+/K(+)-ATPase-dependent sodium efflux in cortical collecting tubule of rabbits under different aldosterone status.
Biochimica et biophysica acta 1990;1022(1):126-8.
1989: Frederic Jaisser; Marcel Blot-Chabaud; P Pradelles; Jean-Pierre Bonvalet; Nicolette Farman
Antidiuretic hormone reduces the high PGE2 synthesis in papillary collecting duct of DI rats.
Pflügers Archiv : European journal of physiology 1989;414(4):464-8.
1989: Frederic Jaisser; L Bugeon; Marcel Blot-Chabaud; Jean-Pierre Bonvalet; Nicolette Farman
Effects of AVP and dDAVP on PGE2 synthesis in superfused cortical collecting tubules.
The American journal of physiology 1989;256(6 Pt 2):F1044-50.
1988: Marcel Blot-Chabaud; Frederic Jaisser; M Gingold; Jean-Pierre Bonvalet; Nicolette Farman
Na+-K+-ATPase-dependent sodium flux in cortical collecting tubule.
The American journal of physiology 1988;255(4 Pt 2):F605-13.