Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Anu Jalanko

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Living Beings

Physiology

Anatomy

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Amino Acid Sequence

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Jalanko Anu; Braulke Thomas
Neuronal ceroid lipofuscinoses.
Uusi-Rauva Kristiina; Luiro Kaisu; Tanhuanpää Kimmo; Kopra Outi; Martín-Vasallo Pablo; Kyttälä Aija; Jalanko Anu
Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex.
Lyly Annina; Marjavaara Sanna K; Kyttälä Aija; Uusi-Rauva Kristiina; Luiro Kaisu; Kopra Outi; Martinez Laurent O; Tanhuanpää Kimmo; Kalkkinen Nisse; Suomalainen Anu; Jauhiainen Matti; Jalanko Anu
Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Anu Jalanko (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Jalanko Anu; Braulke Thomas
Neuronal ceroid lipofuscinoses.
Biochimica et biophysica acta 2009;1793(4):697-709.
2008: Uusi-Rauva Kristiina; Luiro Kaisu; Tanhuanpää Kimmo; Kopra Outi; Martín-Vasallo Pablo; Kyttälä Aija; Jalanko Anu
Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex.
Experimental cell research 2008;314(15):2895-905.
2008: Lyly Annina; Marjavaara Sanna K; Kyttälä Aija; Uusi-Rauva Kristiina; Luiro Kaisu; Kopra Outi; Martinez Laurent O; Tanhuanpää Kimmo; Kalkkinen Nisse; Suomalainen Anu; Jauhiainen Matti; Jalanko Anu
Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism.
Human molecular genetics 2008;17(10):1406-17.
2008: von Schantz Carina; Saharinen Juha; Kopra Outi; Cooper Jonathan D; Gentile Massimiliano; Hovatta Iiris; Peltonen Leena; Jalanko Anu
Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases.
BMC genomics 2008;9():146.
2007: Ahtiainen Laura; Kolikova Julia; Mutka Aino-Liisa; Luiro Kaisu; Gentile Massimiliano; Ikonen Elina; Khiroug Leonard; Jalanko Anu; Kopra Outi
Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction.
Neurobiology of disease 2007;28(1):52-64.
2007: Lehtonen Heli J; Ylisaukko-Oja Sanna K; Kiuru Maija; Karhu Auli; Lehtonen Rainer; Vanharanta Sakari; Jalanko Anu; Aaltonen Lauri A; Launonen Virpi
Stress-induced expression of a novel variant of human fumarate hydratase (FH).
Gene expression 2007;14(2):59-69.
2007: Lyly Annina; von Schantz Carina; Salonen Tarja; Kopra Outi; Saarela Jani; Jauhiainen Matti; Kyttälä Aija; Jalanko Anu
Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1)--distinct characteristics in neurons.
BMC cell biology 2007;8():22.
2006: Jalanko Anu; Tyynelä Jaana; Peltonen Leena
From genes to systems: new global strategies for the characterization of NCL biology.
Biochimica et biophysica acta 2006;1762(10):934-44.
2006: Luiro Kaisu; Kopra Outi; Blom Tomas; Gentile Massimiliano; Mitchison Hannah M; Hovatta Iiris; Törnquist Kid; Jalanko Anu
Batten disease (JNCL) is linked to disturbances in mitochondrial, cytoskeletal, and synaptic compartments.
Journal of neuroscience research 2006;84(5):1124-38.
2006: Virta Salli; Rapola Juhani; Jalanko Anu; Laine Minna
Use of nonviral promoters in adenovirus-mediated gene therapy: reduction of lysosomal storage in the aspartylglucosaminuria mouse.
The journal of gene medicine 2006;8(6):699-706.
2006: Ahtiainen Laura; Luiro Kaisu; Kauppi Maria; Tyynelä Jaana; Kopra Outi; Jalanko Anu
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.
Experimental cell research 2006;312(9):1540-53.
2005: Tyynismaa Henna; Mjosund Katja Peltola; Wanrooij Sjoerd; Lappalainen Ilse; Ylikallio Emil; Jalanko Anu; Spelbrink Johannes N; Paetau Anders; Suomalainen Anu
Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(49):17687-92.
2005: Kyttälä Aija; Yliannala Kristiina; Schu Peter; Jalanko Anu; Luzio J Paul
AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.
The Journal of biological chemistry 2005;280(11):10277-83.
2005: Jalanko Anu; Vesa Jouni; Manninen Tuula; von Schantz Carina; Minye Helena; Fabritius Anna-Liisa; Salonen Tarja; Rapola Juhani; Gentile Massimiliano; Kopra Outi; Peltonen Leena
Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons.
Neurobiology of disease 2005;18(1):226-41.
2004: Tyynismaa Henna; Sembongi Hiroshi; Bokori-Brown Monika; Granycome Caroline; Ashley Neil; Poulton Joanna; Jalanko Anu; Spelbrink Johannes N; Holt Ian J; Suomalainen Anu
Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number.
Human molecular genetics 2004;13(24):3219-27.
2004: Laine M; Ahtiainen L; Rapola J; Richter J; Jalanko A
Bone marrow transplantation in young aspartylglucosaminuria mice: improved clearance of lysosomal storage in brain by using wild type as compared to heterozygote donors.
Bone marrow transplantation 2004;34(11):1001-3.
2004: Luiro Kaisu; Yliannala Kristiina; Ahtiainen Laura; Maunu Heidi; Järvelä Irma; Kyttälä Aija; Jalanko Anu
Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway.
Human molecular genetics 2004;13(23):3017-27.
2004: Kopra Outi; Vesa Jouni; von Schantz Carina; Manninen Tuula; Minye Helena; Fabritius Anna-Liisa; Rapola Juhani; van Diggelen Otto P; Saarela Janna; Jalanko Anu; Peltonen Leena
A mouse model for Finnish variant late infantile neuronal ceroid lipofuscinosis, CLN5, reveals neuropathology associated with early aging.
Human molecular genetics 2004;13(23):2893-906.
2004: Saarela Jani; von Schantz Carina; Peltonen Leena; Jalanko Anu
A novel aspartylglucosaminuria mutation affects translocation of aspartylglucosaminidase.
Human mutation 2004;24(4):350-1.
2004: Holmberg Ville; Jalanko Anu; Isosomppi Juha; Fabritius Anna-Liisa; Peltonen Leena; Kopra Outi
The mouse ortholog of the neuronal ceroid lipofuscinosis CLN5 gene encodes a soluble lysosomal glycoprotein expressed in the developing brain.
Neurobiology of disease 2004;16(1):29-40.
2004: Lonka Liina; Salonen Tarja; Siintola Eija; Kopra Outi; Lehesjoki Anna-Elina; Jalanko Anu
Localization of wild-type and mutant neuronal ceroid lipofuscinosis CLN8 proteins in non-neuronal and neuronal cells.
Journal of neuroscience research 2004;76(6):862-71.
2004: Aula Nina; Kopra Outi; Jalanko Anu; Peltonen Leena
Sialin expression in the CNS implicates extralysosomal function in neurons.
Neurobiology of disease 2004;15(2):251-61.
2004: Saarela Jani; Oinonen Carita; Jalanko Anu; Rouvinen Juha; Peltonen Leena
Autoproteolytic activation of human aspartylglucosaminidase.
The Biochemical journal 2004;378(Pt 2):363-71.
2003: Harkke Salli; Laine Minna; Jalanko Anu
Aspartylglucosaminidase (AGA) is efficiently produced and endocytosed by glial cells: implication for the therapy of a lysosomal storage disorder.
The journal of gene medicine 2003;5(6):472-82.
2003: Ahtiainen Laura; Van Diggelen Otto P; Jalanko Anu; Kopra Outi
Palmitoyl protein thioesterase 1 is targeted to the axons in neurons.
The Journal of comparative neurology 2003;455(3):368-77.
2002: Aula Nina; Jalanko Anu; Aula Pertti; Peltonen Leena
Unraveling the molecular pathogenesis of free sialic acid storage disorders: altered targeting of mutant sialin.
Molecular genetics and metabolism 2002;77(1-2):99-107.
2002: Bondestam Jonas; Kaivo-oja Noora; Kallio Janne; Groome Nigel; Hydén-Granskog Christel; Fujii Makiko; Moustakas Aristidis; Jalanko Anu; ten Dijke Peter; Ritvos Olli
Engagement of activin and bone morphogenetic protein signaling pathway Smad proteins in the induction of inhibin B production in ovarian granulosa cells.
Molecular and cellular endocrinology 2002;195(1-2):79-88.
2002: Vesa Jouni; Chin Mark H; Oelgeschläger Kathrin; Isosomppi Juha; DellAngelica Esteban C; Jalanko Anu; Peltonen Leena
Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3.
Molecular biology of the cell 2002;13(7):2410-20.
2002: Isosomppi Juha; Vesa Jouni; Jalanko Anu; Peltonen Leena
Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein.
Human molecular genetics 2002;11(8):885-91.
2001: Luiro K; Kopra O; Lehtovirta M; Jalanko A
CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease.
Human molecular genetics 2001;10(19):2123-31.
2001: Salonen T; Heinonen-Kopra O; Vesa J; Jalanko A
Neuronal trafficking of palmitoyl protein thioesterase provides an excellent model to study the effects of different mutations which cause infantile neuronal ceroid lipofuscinocis.
Molecular and cellular neurosciences 2001;18(2):131-40.
2001: Saarela J; Laine M; Oinonen C; Schantz C; Jalanko A; Rouvinen J; Peltonen L
Molecular pathogenesis of a disease: structural consequences of aspartylglucosaminuria mutations.
Human molecular genetics 2001;10(9):983-95.
2001: Lehtovirta M; Kyttälä A; Eskelinen E L; Hess M; Heinonen O; Jalanko A
Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons: implications for infantile neuronal ceroid lipofuscinosis (INCL).
Human molecular genetics 2001;10(1):69-75.
2000: Heinonen O; Salonen T; Jalanko A; Peltonen L; Copp A
CLN-1 and CLN-5, genes for infantile and variant late infantile neuronal ceroid lipofuscinoses, are expressed in the embryonic human brain.
The Journal of comparative neurology 2000;426(3):406-12.
2000: Lonka L; Kyttälä A; Ranta S; Jalanko A; Lehesjoki A E
The neuronal ceroid lipofuscinosis CLN8 membrane protein is a resident of the endoplasmic reticulum.
Human molecular genetics 2000;9(11):1691-7.
2000: Heinonen O; Kyttälä A; Lehmus E; Paunio T; Peltonen L; Jalanko A
Expression of palmitoyl protein thioesterase in neurons.
Molecular genetics and metabolism 2000;69(2):123-9.
2000: Salonen T; Järvelä I; Peltonen L; Jalanko A
Detection of eight novel palmitoyl protein thioesterase (PPT) mutations underlying infantile neuronal ceroid lipofuscinosis (INCL;CLN1).
Human mutation 2000;15(3):273-9.
1999: Isosomppi J; Heinonen O; Hiltunen J O; Greene N D; Vesa J; Uusitalo A; Mitchison H M; Saarma M; Jalanko A; Peltonen L
Developmental expression of palmitoyl protein thioesterase in normal mice.
Brain research. Developmental brain research 1999;118(1-2):1-11.
1999: Laine M; Richter J; Fahlman C; Rapola J; Renlund M; Peltonen L; Karlsson S; Jalanko A
Correction of peripheral lysosomal accumulation in mice with aspartylglucosaminuria by bone marrow transplantation.
Experimental hematology 1999;27(9):1467-74.
1999: Uusitalo A; Tenhunen K; Heinonen O; Hiltunen J O; Saarma M; Haltia M; Jalanko A; Peltonen L
Toward understanding the neuronal pathogenesis of aspartylglucosaminuria: expression of aspartylglucosaminidase in brain during development.
Molecular genetics and metabolism 1999;67(4):294-307.
1999: Kangas H; Ulmanen I; Paunio T; Kwiatkowski D J; Lehtovirta M; Jalanko A; Peltonen L
Functional consequences of amyloidosis mutation for gelsolin polypeptide -- analysis of gelsolin-actin interaction and gelsolin processing in gelsolin knock-out fibroblasts.
FEBS letters 1999;454(3):233-9.
1999: Järvelä I; Lehtovirta M; Tikkanen R; Kyttälä A; Jalanko A
Defective intracellular transport of CLN3 is the molecular basis of Batten disease (JNCL)
Human molecular genetics 1999;8(6):1091-8.
1999: Peltonen L; Jalanko A; Varilo T
Molecular genetics of the Finnish disease heritage.
Human molecular genetics 1999;8(10):1913-23.
1998: Tenhunen K; Uusitalo A; Autti T; Joensuu R; Kettunen M; Kauppinen R A; Ikonen S; LaMarca M E; Haltia M; Ginns E I; Jalanko A; Peltonen L
Monitoring the CNS pathology in aspartylglucosaminuria mice.
Journal of neuropathology and experimental neurology 1998;57(12):1154-63.
1998: Peltola M; Kyttälä A; Heinonen O; Rapola J; Paunio T; Revah F; Peltonen L; Jalanko A
Adenovirus-mediated gene transfer results in decreased lysosomal storage in brain and total correction in liver of aspartylglucosaminuria (AGU) mouse.
Gene therapy 1998;5(10):1314-21.
1998: Kyttälä A; Heinonen O; Peltonen L; Jalanko A
Expression and endocytosis of lysosomal aspartylglucosaminidase in mouse primary neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(19):7750-6.
1998: Saarela J; Laine M; Tikkanen R; Oinonen C; Jalanko A; Rouvinen J; Peltonen L
Activation and oligomerization of aspartylglucosaminidase.
The Journal of biological chemistry 1998;273(39):25320-8.
1998: Salonen T; Hellsten E; Horelli-Kuitunen N; Peltonen L; Jalanko A
Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA.
Genome research 1998;8(7):724-30.
1998: Jalanko A; Tenhunen K; McKinney C E; LaMarca M E; Rapola J; Autti T; Joensuu R; Manninen T; Sipilä I; Ikonen S; Riekkinen P; Ginns E I; Peltonen L
Mice with an aspartylglucosaminuria mutation similar to humans replicate the pathophysiology in patients.
Human molecular genetics 1998;7(2):265-72.
1998: Järvelä I; Sainio M; Rantamäki T; Olkkonen V M; Carpén O; Peltonen L; Jalanko A
Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease.
Human molecular genetics 1998;7(1):85-90.
1997: Mikkola H; Muszbek L; Haramura G; Hämäläinen E; Jalanko A; Palotie A
Molecular mechanisms of mutations in factor XIII A-subunit deficiency: in vitro expression in COS-cells demonstrates intracellular degradation of the mutant proteins.
Thrombosis and haemostasis 1997;77(6):1068-72.
1997: Uusitalo A; Tenhunen K; Tenhunen J; Matikainen S; Peltonen L; Jalanko A
Expression and regulation of the human and mouse aspartylglucosaminidase gene.
The Journal of biological chemistry 1997;272(14):9524-30.
1997: Hellsten E; Vesa J; Jalanko A; Peltonen L
From locus to cellular disturbances: positional cloning of the infantile neuronal ceroid lipofuscinosis gene.
Neuropediatrics 1997;28(1):9-11.
1996: Hellsten E; Vesa J; Olkkonen V M; Jalanko A; Peltonen L
Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis.
The EMBO journal 1996;15(19):5240-5.
1996: Kangas H; Paunio T; Kalkkinen N; Jalanko A; Peltonen L
In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis.
Human molecular genetics 1996;5(9):1237-43.
1996: Riikonen A; Rouvinen J; Tikkanen R; Julkunen I; Peltonen L; Jalanko A
Primary folding of aspartylglucosaminidase. Significance of disulfide bridges and evidence of early multimerization.
The Journal of biological chemistry 1996;271(35):21340-4.
1996: Peltola M; Tikkanen R; Peltonen L; Jalanko A
Ser72Pro active-site disease mutation in human lysosomal aspartylglucosaminidase: abnormal intracellular processing and evidence for extracellular activation.
Human molecular genetics 1996;5(6):737-43.
1996: Jalanko A; Ranki M; Palotie L
[Diseases and gene defects]
Duodecim; lääketieteellinen aikakauskirja 1996;112(4):307-14.
1995: Tenhunen K; Laan M; Manninen T; Palotie A; Peltonen L; Jalanko A
Molecular cloning, chromosomal assignment, and expression of the mouse aspartylglucosaminidase gene.
Genomics 1995;30(2):244-50.
1995: Enomaa N; Danos O; Peltonen L; Jalanko A
Correction of deficient enzyme activity in a lysosomal storage disease, aspartylglucosaminuria, by enzyme replacement and retroviral gene transfer.
Human gene therapy 1995;6(6):723-31.
1995: Riikonen A; Tikkanen R; Jalanko A; Peltonen L
Immediate interaction between the nascent subunits and two conserved amino acids Trp34 and Thr206 are needed for the catalytic activity of aspartylglucosaminidase.
The Journal of biological chemistry 1995;270(9):4903-7.
1995: Jalanko A; Manninen T; Peltonen L
Deletion of the C-terminal end of aspartylglucosaminidase resulting in a lysosomal accumulation disease: evidence for a unique genomic rearrangement.
Human molecular genetics 1995;4(3):435-41.
1995: Isoniemi A; Hietala M; Aula P; Jalanko A; Peltonen L
Identification of a novel mutation causing aspartylglucosaminuria reveals a mutation hotspot region in the aspartylglucosaminidase gene.
Human mutation 1995;5(4):318-26.
1994: Peltola M; Chiatayat D; Peltonen L; Jalanko A
Characterization of a point mutation in aspartylglucosaminidase gene: evidence for a readthrough of a translational stop codon.
Human molecular genetics 1994;3(12):2237-42.
1994: Brunetto M R; Randone A; Ranki M; Jalanko A; Piantino P; Giarin M; Capra G; Calvo P L; Oliveri F; Bonino F
Quantitative analysis of wild-type and HBeAg minus hepatitis B viruses by a sequence-dependent primer extension assay.
Journal of medical virology 1994;43(3):310-5.
1994: Riikonen A; Ikonen E; Sormunen R; Lehto V P; Peltonen L; Jalanko A
Dissection of the molecular consequences of a double mutation causing a human lysosomal disease.
DNA and cell biology 1994;13(3):257-64.
1993: Harju L; Weber T; Alexandrova L; Lukin M; Ranki M; Jalanko A
Colorimetric solid-phase minisequencing assay illustrated by detection of alpha 1-antitrypsin Z mutation.
Clinical chemistry 1993;39(11 Pt 1):2282-7.
1993: Tenhunen J; Salminen M; Jalanko A; Ukkonen S; Ulmanen I
Structure of the rat catechol-O-methyltransferase gene: separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme.
DNA and cell biology 1993;12(3):253-63.
1992: Tilgmann C; Melen K; Lundström K; Jalanko A; Julkunen I; Kalkkinen N; Ulmanen I
Expression of recombinant soluble and membrane-bound catechol O-methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain.
European journal of biochemistry / FEBS 1992;207(2):813-21.
1992: Jalanko A; Kere J; Savilahti E; Schwartz M; Syvänen A C; Ranki M; Söderlund H
Screening for defined cystic fibrosis mutations by solid-phase minisequencing.
Clinical chemistry 1992;38(1):39-43.
1991: Lundström K; Salminen M; Jalanko A; Savolainen R; Ulmanen I
Cloning and characterization of human placental catechol-O-methyltransferase cDNA.
DNA and cell biology 1991;10(3):181-9.
1989: Jalanko A; Kallio A; Salminen M; Ulmanen I
Efficient synthesis of influenza virus hemagglutinin in mammalian cells with an extrachromosomal Epstein-Barr virus vector.
Gene 1989;78(2):287-96.
1988: Jalanko A; Kallio A; Ruohonen-Lehto M; Söderlund H; Ulmanen I
An EBV-based mammalian cell expression vector for efficient expression of cloned coding sequences.
Biochimica et biophysica acta 1988;949(2):206-12.
1988: Jalanko A; Kallio A; Ulmanen I
Comparison of mammalian cell expression vectors with and without an EBV-replicon.
Archives of virology 1988;103(3-4):157-66.
1985: Jalanko A; Söderlund H
The repeated regions of Semliki Forest virus defective-inferfering RNA interferes with the encapsidation process of the standard virus.
Virology 1985;141(2):257-66.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Anu Jalanko

Research Profile (preview)

Chemicals & Drugs

Disorders

Living Beings

Physiology

Anatomy

Concepts & Ideas

Genes & Molecular Sequences

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Anu Jalanko (preview)

All Publications