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David James

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Pin-Yuan Chen; Daryl C Drummond; Jonathan B Fitzgerald; John R Forsayeth; Ashish Kalra; Dmitri B Kirpotin; Tomoko Ozawa; Michael D Prados; Kuo-Chen Wei; Krystof Bankiewicz; Mitchel S Berger; Nicholas Butowski; C David James
Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts.
Joachim Silber; Scott R Vandenberg; Mamie Yu; Mitchel S Berger; Tristan Felix; Sujatmi Hariono; Rintaro Hashizume; J Graeme Hodgson; Jason Huse; C David James; Nalin Gupta
Expression of miR-124 inhibits growth of medulloblastoma cells.
Rintaro Hashizume; Jeanette Hyer; C David James; Sharon Liu; Tracy R McKnight; Sabine Mueller; Theodore paul nicolaides; Joanna J Phillips; Michael Prados; Ivan Smirnov; Michael Wendland; Anu Banerjee; Nalin Gupta
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.

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2013: Pin-Yuan Chen; Daryl C Drummond; Jonathan B Fitzgerald; John R Forsayeth; Ashish Kalra; Dmitri B Kirpotin; Tomoko Ozawa; Michael D Prados; Kuo-Chen Wei; Krystof Bankiewicz; Mitchel S Berger; Nicholas Butowski; C David James
Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts.
Neuro-oncology 2013;15(2):189-97.
2013: Joachim Silber; Scott R Vandenberg; Mamie Yu; Mitchel S Berger; Tristan Felix; Sujatmi Hariono; Rintaro Hashizume; J Graeme Hodgson; Jason Huse; C David James; Nalin Gupta
Expression of miR-124 inhibits growth of medulloblastoma cells.
Neuro-oncology 2013;15(1):83-90.
2012: Rintaro Hashizume; Jeanette Hyer; C David James; Sharon Liu; Tracy R McKnight; Sabine Mueller; Theodore paul nicolaides; Joanna J Phillips; Michael Prados; Ivan Smirnov; Michael Wendland; Anu Banerjee; Nalin Gupta
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
Journal of neuro-oncology 2012;110(3):305-13.
2012: Myriam M Chaumeil; Beatrice Gini; Akio Iwanami; C David James; Paul S Mischel; Tomoko Ozawa; Russel O Pieper; Subramaniam Sukumar; Huijun Yang; Mitchel S Berger; Sabrina M Ronen
Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1 tesla.
Neuro-oncology 2012;14(8):1050-61.
2012: Christine K Cheng; Elizabeth Charron; Andrei Goga; Nathanael S Gray; W Clay Gustafson; Benjamin T Houseman; C David James; Scott A Oakes; Brian Pollok; Kevan M Shokat; William A Weiss; Eli Zunder; Qi-Wen Fan
Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):12722-7.
2012: Emmanuelle Huillard; Rebecca A Ihrie; C David James; Martin McMahon; Theodore paul nicolaides; Arie Perry; Claudia Petritsch; Joanna J Phillips; Yasuyuki Aoki; Amélie Griveau; Rintaro Hashizume; Todd Waldman; William A Weiss; David H Rowitch
Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(22):8710-5.
2012: Laura P Serwer; C David James
Challenges in drug delivery to tumors of the central nervous system: an overview of pharmacological and surgical considerations.
Advanced drug delivery reviews 2012;64(7):590-7.
2012: Yasuyuki Aoki; Anu Banerjee; Rintaro Hashizume; C David James; Tomoko Ozawa; Michael Prados; Nalin Gupta
An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing.
Journal of neuro-oncology 2012;108(1):29-35.
2012: Humsa S Venkatesh; Christopher S Ward; Myriam M Chaumeil; Daphne A Haas-Kogan; C David James; Sabrina M Ronen
Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
Neuro-oncology 2012;14(3):315-25.
2012: Myriam M Chaumeil; C David James; Sarah J Nelson; Tomoko Ozawa; IlWoo Park; Kristen Scott; Sabrina M Ronen
Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma.
NeuroImage 2012;59(1):193-201.
2012: Jane R Engler; Nalin Gupta; J Graeme Hodgson; C David James; Annette Molinaro; Aaron E Robinson; Ivan Smirnov; Mitchel S Berger; Joanna J Phillips
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.
PloS one 2012;7(8):e43339.
2012: L Gerard Toussaint; Karla V Ballman; Jennie M Goble; C David James; Robert Kiss; Florence Lefranc; Allan E Nilson; Joon H Uhm
Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion.
Molecular cancer 2012;11():32.
2011: Laura P Serwer; Daryl C Drummond; Dmitri B Kirpotin; Karine Michaud; Charles O Noble; Tomoko Ozawa; John W Park; Michael D Prados; C David James
Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts.
Neuro-oncology 2011;13(12):1288-95.
2011: Ilwoo Park; Robert Bok; Tomoko Ozawa; Joanna J Phillips; C David James; Daniel B Vigneron; Sabrina M Ronen; Sarah J Nelson
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
Journal of magnetic resonance imaging : JMRI 2011;33(6):1284-90.
2011: Gautam Prasad; Theo Sottero; Xiaodong Yang; Sabine Mueller; C David James; William A Weiss; Mei-Yin Polley; Tomoko Ozawa; Mitchel S Berger; Dana T Aftab; Michael D Prados; Daphne A Haas-Kogan
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
Neuro-oncology 2011;13(4):384-92.
2010: Xiaodong Zhu; Scott Bidlingmaier; Rintaro Hashizume; C David James; Mitchel S Berger; Bin Liu
Identification of internalizing human single-chain antibodies targeting brain tumor sphere cells.
Molecular cancer therapeutics 2010;9(7):2131-41.
2010: Fredrik J Swartling; Matthew R Grimmer; Christopher S Hackett; Paul A Northcott; Qi-Wen Fan; David D Goldenberg; Jasmine Lau; Selma Masic; Kim Nguyen; Slava Yakovenko; Xiao-Ning Zhe; Heather C Flynn Gilmer; Rodney Collins; Mai Nagaoka; Joanna J Phillips; Robert B Jenkins; Tarik Tihan; Scott R Vandenberg; C David James; Kohichi Tanaka; Michael D Taylor; William A Weiss; Louis Chesler
Pleiotropic role for MYCN in medulloblastoma.
Genes & development 2010;24(10):1059-72.
2010: Karine Michaud; David A Solomon; Eric Oermann; Jung-Sik Kim; Wei-Zhu Zhong; Michael D Prados; Tomoko Ozawa; C David James; Todd Waldman
Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.
Cancer research 2010;70(8):3228-38.
2010: Ruihuan Chen; Merry C Nishimura; Stephanie M Bumbaca; Samir Kharbanda; William F Forrest; Ian Kasman; Joan M Greve; Robert Soriano; Laurie L Gilmour; Celina Sanchez Rivers; Zora Modrusan; Serban Nacu; Steve Guerrero; Kyle A Edgar; Jeffrey J Wallin; Katrin Lamszus; Manfred Westphal; Susanne Heim; C David James; Scott R Vandenberg; Joseph F Costello; Scott Moorefield; Cynthia J Cowdrey; Michael Prados; Heidi S Phillips
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
Cancer cell 2010;17(4):362-75.
2010: Christopher S Ward; Humsa S Venkatesh; Myriam M Chaumeil; Alissa H Brandes; Mark Vancriekinge; Hagit Dafni; Subramaniam Sukumar; Sarah J Nelson; Daniel B Vigneron; John Kurhanewicz; C David James; Daphne A Haas-Kogan; Sabrina M Ronen
Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.
Cancer research 2010;70(4):1296-305.
2010: Ilwoo Park; Peder E Z Larson; Matthew L Zierhut; Simon Hu; Robert Bok; Tomoko Ozawa; John Kurhanewicz; Daniel B Vigneron; Scott R Vandenberg; C David James; Sarah J Nelson
Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
Neuro-oncology 2010;12(2):133-44.
2010: Joshua Schiffman; J Graeme Hodgson; Scott R Vandenberg; Patrick Flaherty; Mei-Yin C Polley; Mamie Yu; Paul G Fisher; David H Rowitch; James M Ford; Mitchel S Berger; Hanlee Ji; David H Gutmann; C David James
Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.
Cancer research 2010;70(2):512-9.
2010: Bruno M Costa; Justin S Smith; Ying Chen; Justin Chen; Heidi S Phillips; Kenneth Aldape; Giuseppe Zardo; Janice M Nigro; C David James; Jane Fridlyand; Rui M Reis; Joseph F Costello
Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.
Cancer research 2010;70(2):453-62.
2010: Qi-Wen Fan; Christine Cheng; Christopher S Hackett; Morri Feldman; Benjamin T Houseman; Theodore paul nicolaides; Daphne A Haas-Kogan; C David James; Scott A Oakes; Jayanta Debnath; Kevan M Shokat; William A Weiss
Akt and autophagy cooperate to promote survival of drug-resistant glioma.
Science signaling 2010;3(147):ra81.
2009: J Graeme Hodgson; Ru-Fang Yeh; Amrita Ray; Nicholas J Wang; Ivan Smirnov; Mamie Yu; Sujatmi Hariono; Joachim Silber; Heidi S Feiler; Joe Gray; Paul Spellman; Scott R Vandenberg; Mitchel S Berger; C David James
Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts.
Neuro-oncology 2009;11(5):477-87.
2009: Brett L Carlson; Patrick T Grogan; Ann C Mladek; Mark A Schroeder; Gaspar Kitange; Paul A Decker; Caterina Giannini; Wenting Wu; Karla A Ballman; C David James; Jann N. Sarkaria
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
International journal of radiation oncology, biology, physics 2009;75(1):212-9.
2009: Kan V Lu; Shaojun Zhu; Anna Cvrljevic; Tiffany T Huang; Shawn Sarkaria; David Ahkavan; Jeff Dang; Eduard B Dinca; Seema B Plaisier; Isaac Oderberg; Yohan Lee; Zugen Chen; Jeremy S Caldwell; Yongmin Xie; Joseph A Loo; David Seligson; Arnab Chakravari; Francis Y Lee; Roberto Weinmann; Timothy F Cloughesy; Stanley F Nelson; Gabriele Bergers; Thomas Graeber; Frank B Furnari; C David James; Webster K Cavenee; Terrance G Johns; Paul S Mischel
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.
Cancer research 2009;69(17):6889-98.
2009: Gaspar Kitange; Brett L Carlson; Mark A Schroeder; Patrick T Grogan; Jeff D Lamont; Paul A Decker; Wenting Wu; C David James; Jann N. Sarkaria
Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts.
Neuro-oncology 2009;11(3):281-91.
2009: Cigall Kadoch; Eduard B Dinca; Ramona Voicu; Lingjing Chen; Diana Nguyen; Seema Parikh; Juliana Karrim; Marc A Shuman; Clifford A Lowell; Patrick A Treseler; C David James; James L Rubenstein
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):1989-97.
2009: Michael D Prados; Susan M Chang; Nicholas Butowski; Rebecca DeBoer; Rupa Parvataneni; Hannah Carliner; Paul Kabuubi; Jennifer Ayers-Ringler; Jane Rabbitt; Margaretta Page; Anne Fedoroff; Penny K Sneed; Mitchel S Berger; Michael W McDermott; Andrew T Parsa; Scott Vandenberg; C David James; Kathleen R Lamborn; David Stokoe; Daphne A Haas-Kogan
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(4):579-84.
2009: Michael E Sughrue; Isaac Yang; Ari J Kane; Martin J Rutkowski; Shanna Fang; C David James; Andrew T Parsa
Immunological considerations of modern animal models of malignant primary brain tumors.
Journal of translational medicine 2009;7():84.
2009: Joachim Silber; C David James; J Graeme Hodgson
microRNAs in gliomas: small regulators of a big problem.
Neuromolecular medicine 2009;11(3):208-22.
2009: Qi-Wen Fan; Christine Cheng; Zachary A Knight; Daphne A Haas-Kogan; David Stokoe; C David James; Frank McCormick; Kevan M Shokat; William A Weiss
EGFR signals to mTOR through PKC and independently of Akt in glioma.
Science signaling 2009;2(55):ra4.
2008: Lin Yang; Michelle Clarke; Brett L Carlson; Ann C Mladek; Mark A Schroeder; Paul Decker; Wenting Wu; Gaspar Kitange; Patrick T Grogan; Jennie M Goble; Joon H Uhm; Evanthia C Galanis; Caterina Giannini; Heidi A Lane; C David James; Jann N. Sarkaria
PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3993-4001.
2008: Jann N. Sarkaria; Gaspar Kitange; C David James; Ruth Plummer; Hilary Calvert; Michael Weller; Wolfgang Wick
Mechanisms of chemoresistance to alkylating agents in malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):2900-8.
2008: Gilson Baia; Eduard B Dinca; Tomoko Ozawa; Edna T Kimura; Michael W McDermott; C David James; Scott R Vandenberg; Anita Lal
An orthotopic skull base model of malignant meningioma.
Brain pathology (Zurich, Switzerland) 2008;18(2):172-9.
2008: John H Chi; Amith Panner; Kristine Cachola; Courtney A Crane; Joseph Murray; Russell O Pieper; C David James; Andrew T Parsa
Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.
Journal of neurosurgery 2008;108(2):299-303.
2008: Joachim Silber; Daniel A Lim; Claudia Petritsch; Anders I Persson; Alika K Maunakea; Mamie Yu; Scott R Vandenberg; David Ginzinger; C David James; Joseph F Costello; Gabriele Bergers; William A Weiss; Arturo Alvarez-Buylla; J Graeme Hodgson
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.
BMC medicine 2008;6():14.
2007: Chunsheng Liu; Jann N. Sarkaria; Cory A Petell; Georgia Paraskevakou; Paula J Zollman; Mark Schroeder; Brett Carlson; Paul A Decker; Wenting Wu; C David James; stephen russell; Evanthia C Galanis
Combination of measles virus virotherapy and radiation therapy has synergistic activity in the treatment of glioblastoma multiforme.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7155-65.
2007: Eduard B Dinca; Jann N. Sarkaria; Mark A Schroeder; Brett L Carlson; Ramona Voicu; Nalin Gupta; Mitchel S Berger; C David James
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
Journal of neurosurgery 2007;107(3):610-6.
2007: Georgia Paraskevakou; Cory Allen; Takafumi Nakamura; Paula J Zollman; C David James; Kah-Whye Peng; Mark Schroeder; stephen russell; Evanthia C Galanis
Epidermal growth factor receptor (EGFR)-retargeted measles virus strains effectively target EGFR- or EGFRvIII expressing gliomas.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(4):677-86.
2007: Jann N. Sarkaria; Lin Yang; Patrick T Grogan; Gaspar Kitange; Brett L Carlson; Mark A Schroeder; Evanthia C Galanis; Caterina Giannini; Wenting Wu; Eduard B Dinca; C David James
Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel.
Molecular cancer therapeutics 2007;6(3):1167-74.
2006: Cory Allen; Sompong Vongpunsawad; Takafumi Nakamura; C David James; Mark Schroeder; Roberto Cattaneo; Caterina Giannini; James Krempski; Kah-Whye Peng; Jenny M Goble; Joon H Uhm; stephen russell; Evanthia C Galanis
Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity.
Cancer research 2006;66(24):11840-50.
2006: Jann N. Sarkaria; Brett L Carlson; Mark A Schroeder; Patrick T Grogan; Paul D Brown; Caterina Giannini; Karla V Ballman; Gaspar Kitange; Abjahit Guha; Ajay Pandita; C David James
Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2264-71.
2005: Ravi D Rao; Ann C Mladek; Jeffrey D Lamont; Jennie M Goble; Charles Erlichman; C David James; Jann N. Sarkaria
Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Neoplasia (New York, N.Y.) 2005;7(10):921-9.
2005: Caterina Giannini; Jann N. Sarkaria; Atsushi Saito; Joon H Uhm; Evanthia C Galanis; Brett L Carlson; Mark A Schroeder; C David James
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme.
Neuro-oncology 2005;7(2):164-76.
2005: Takafumi Nakamura; Kah-Whye Peng; Mary Harvey; Suzanne Greiner; Ian A J Lorimer; C David James; stephen russell
Rescue and propagation of fully retargeted oncolytic measles viruses.
Nature biotechnology 2005;23(2):209-14.
2004: Jeffrey J Olson; C David James; D H Lawson; Steven Hunter; Gordon Tang; Judy Billingsley
Correlation of the response of recurrent malignant gliomas treated with interferon alpha with tumor interferon alpha gene content.
International journal of oncology 2004;25(2):419-27.
2004: Ajay Pandita; Kenneth Aldape; Gelareh Zadeh; Abhijit Guha; C David James
Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR.
Genes, chromosomes & cancer 2004;39(1):29-36.
2003: Ravi D Rao; Joon H Uhm; Sunil Krishnan; C David James
Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.
Frontiers in bioscience : a journal and virtual library 2003;8():e270-80.
2003: Gordon W Dewald; Stephanie R Brockman; Sarah F Paternoster; Nancy D Bone; Judith R O'Fallon; Cristine Allmer; C David James; Diane F Jelinek; Renee C Tschumper; Curtis A Hanson; Rajiv K Pruthi; Thomas E Witzig; Timothy G Call; Neil E Kay
Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia.
British journal of haematology 2003;121(2):287-95.
2003: Soyeon Park; C David James
Lanthionine synthetase components C-like 2 increases cellular sensitivity to adriamycin by decreasing the expression of P-glycoprotein through a transcription-mediated mechanism.
Cancer research 2003;63(3):723-7.
2003: Sunil Krishnan; Ravi D Rao; C David James; Jann N. Sarkaria
Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas.
Frontiers in bioscience : a journal and virtual library 2003;8():e1-13.
2002: Ozlem Kurtkaya-Yapicier; Bernd W Scheithauer; Deanne Hebrink; C David James
p53 in nonneoplastic central nervous system lesions: an immunohistochemical and genetic sequencing study.
Neurosurgery 2002;51(5):1246-54; discussion 1254-5.
2002: Greg D Eley; Jill L Reiter; Ajay Pandita; Soyeon Park; Robert B Jenkins; Nita Maihle; C David James
A chromosomal region 7p11.2 transcript map: its development and application to the study of EGFR amplicons in glioblastoma.
Neuro-oncology 2002;4(2):86-94.
2001: JS Smith; Issei Tachibana; Sandra Passe; Brenda K Huntley; Thomas J Borell; Nancy L Iturria; Judith R O'Fallon; Paul L Schaefer; Bernd W Scheithauer; C David James; Jan C Buckner; Robert B Jenkins
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.
Journal of the National Cancer Institute 2001;93(16):1246-56.
2001: Viji Shridhar; John Lee; Ajay Pandita; Stephen J Iturria; Rajeswari Avula; Julie Staub; M Morrissey; E Calhoun; A Sen; Kimberly R Kalli; Gary L Keeney; P Roche; William A Cliby; K Lu; Rosemarie Schmandt; Gordon B Mills; Robert C Bast; C David James; Fergus J. Couch; Lynn C Hartmann; Jim Lillie; David I Smith
Genetic analysis of early- versus late-stage ovarian tumors.
Cancer research 2001;61(15):5895-904.
2001: C Giannini; David D Hebrink; B W Scheithauer; A P Dei Tos; C David James
Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma.
Neurogenetics 2001;3(3):159-62.
2001: Charles Erlichman; Scott A Boerner; C G Hallgren; R Spieker; X Y Wang; C David James; George L Scheffer; Marc Maliepaard; Douglas Ross; Keith C Bible; Scott H Kaufmann
The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux.
Cancer research 2001;61(2):739-48.
2001: Jill L Reiter; David Threadgill; Greg D Eley; Karen Strunk; Andrew J Danielsen; C S Sinclair; R Scott Pearsall; P J Green; D Yee; A L Lampland; S Balasubramaniam; T D Crossley; Terry Magnuson; C David James; Nita Maihle
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.
Genomics 2001;71(1):1-20.
2000: H Jacobus Gilhuis; Kari L Anderl; Rudolf H Boerman; J M Jeuken; C David James; Corey Raffel; Bernd W Scheithauer; Robert B Jenkins
Comparative genomic hybridization of medulloblastomas and clinical relevance: eleven new cases and a review of the literature.
Clinical neurology and neurosurgery 2000;102(4):203-209.
2000: Guojun Wu ; Colleen S Sinclair; J Paape; James N Ingle; Patrick C Roche; C David James; Fergus J. Couch
17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes.
Cancer research 2000;60(19):5371-5.
2000: Linda M Frederick; Greg D Eley; XY Wang; C David James
Analysis of genomic rearrangements associated with EGRFvIII expression suggests involvement of Alu repeat elements.
Neuro-oncology 2000;2(3):159-63.
2000: Jaclyn A Biegel; B Fogelgren; JY Zhou; C David James; Anna Janss; J C Allen; David Zagzag; Corey Raffel; Lucy B Rorke
Mutations of the INI1 rhabdoid tumor suppressor gene in medulloblastomas and primitive neuroectodermal tumors of the central nervous system.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2759-63.
2000: Linda M Frederick; XY Wang; Greg D Eley; C David James
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.
Cancer research 2000;60(5):1383-7.
2000: Jill L Reiter; Greg D Eley; C David James; Nita Maihle
Correspondence re: S. Shintani et al., Intragenic mutation analysis of the human epidermal growth factor receptor (EGFR) gene in malignant human oral keratinocytes. Cancer Res., 59: 4142-4147, 1999.
Cancer research 2000;60(3):766-7.
1999: Corey Raffel; Linda M Frederick; Judith R O'Fallon; P Atherton-Skaff; A Perry; Robert B Jenkins; C David James
Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(12):4085-90.
1999: C David James; Evanthia C Galanis; Linda M Frederick; David W Kimmel; Julie M Cunningham; P J Atherton-Skaff; Judith R O'Fallon; Robert B Jenkins; Jan C Buckner; Stephen B Hunter; Jeffrey J Olson; Bernd W Scheithauer
Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation.
International journal of oncology 1999;15(3):547-53.
1999: Cargill Herley Alleyne; J He; J Yang; Stephen B Hunter; George Cotsonis; C David James; Jeffrey J Olson
Analysis of cyclin dependent kinase inhibitors in malignant astrocytomas.
International journal of oncology 1999;14(6):1111-6.
1999: Fergus J. Couch; XY Wang; Guojun Wu ; Junqi Qian; Robert B Jenkins; C David James
Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer.
Cancer research 1999;59(7):1408-11.
1998: Greg D Eley; Linda M Frederick; XY Wang; David I Smith; C David James
3' end structure and rearrangements of EGFR in glioblastomas.
Genes, chromosomes & cancer 1998;23(3):248-54.
1998: Evanthia C Galanis; J Buckner; David W Kimmel; R Jenkins; BE Alderete; Judith R O'Fallon; C H Wang; Bernd W Scheithauer; C David James
Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas.
International journal of oncology 1998;13(4):717-24.
1998: X Y Wang; David I Smith; Wanguo Liu; C David James
GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR.
Genomics 1998;49(3):448-51.
1998: Wanguo Liu; David I Smith; K J Rechtzigel; Stephen N Thibodeau; C David James
Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations.
Nucleic acids research 1998;26(6):1396-400.
1998: XY Wang; David I Smith; Linda M Frederick; C David James
Analysis of EGF receptor amplicons reveals amplification of multiple expressed sequences.
Oncogene 1998;16(2):191-5.
1998: Jeffrey J Olson; D Barnett; J Yang; R Assietti; George Cotsonis; C David James
Gene amplification as a prognostic factor in primary brain tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(1):215-22.
1997: Wanguo Liu; C David James; Linda M Frederick; BE Alderete; Robert B Jenkins
PTEN/MMAC1 mutations and EGFR amplification in glioblastomas.
Cancer research 1997;57(23):5254-7.
1997: Corey Raffel; Robert B Jenkins; Linda M Frederick; David D Hebrink; BE Alderete; D W Fults; C David James
Sporadic medulloblastomas contain PTCH mutations.
Cancer research 1997;57(5):842-5.
1996: J He; Jeffrey J Olson; A J Ekstrand; A Serbanescu; J Yang; Margaret Offermann; C David James
Transfection of IFNalpha in human glioblastoma cells and tumorigenicity in association with induction of PKR and OAS gene expression.
Journal of neurosurgery 1996;85(6):1085-90.
1996: Joseph Petronio; J He; Daniel W Fults; C Pedone; C David James; J R Allen
Common alternative gene alterations in adult malignant astrocytomas, but not in childhood primitive neuroectodermal tumors: P 16ink4 homozygous deletions and CDK4 gene amplifications.
Journal of neurosurgery 1996;84(6):1020-3.
1996: C David James; Jeffrey J Olson
Molecular genetics and molecular biology advances in brain tumors.
Current opinion in oncology 1996;8(3):188-95.
1995: J He; Jeffrey J Olson; C David James
Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines.
Cancer research 1995;55(21):4833-6.
1995: Muxiang Zhou; Lubing Gu; C David James; J He; Andrew M Yeager; S D Smith; Harry W Findley
Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.
Leukemia 1995;9(7):1159-61.
1995: A J Ekstrand; L Liu; J He; M L Hamid; N Longo; V P Collins; C David James
Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.
Oncogene 1995;10(7):1455-60.
1995: Jeffrey J Olson; C David James; A Krisht; D Barnett; S Hunter
Analysis of epidermal growth factor receptor gene amplification and alteration in stereotactic biopsies of brain tumors.
Neurosurgery 1995;36(4):740-6; discussion 747-8.
1995: Stephen B Hunter; Karen L. Abbott; V A Varma; Jeffrey J Olson; D W Barnett; C David James
Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue.
Journal of neuropathology and experimental neurology 1995;54(1):57-64.
1994: J He; J R Allen; V P Collins; M Joan Allalunis-Turner; R Godbout; R S Day; C David James
CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines.
Cancer research 1994;54(22):5804-7.
1994: J He; Guido Reifenberger; L Liu; V P Collins; C David James
Analysis of glioma cell lines for amplification and overexpression of MDM2.
Genes, chromosomes & cancer 1994;11(2):91-6.
1994: A J Ekstrand; N Longo; M L Hamid; Jeffrey J Olson; L Liu; V P Collins; C David James
Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification.
Oncogene 1994;9(8):2313-20.
1993: C David James; J He; V P Collins; M Joan Allalunis-Turner; R S Day
Localization of chromosome 9p homozygous deletions in glioma cell lines with markers constituting a continuous linkage group.
Cancer research 1993;53(16):3674-6.
1992: A J Ekstrand; N Sugawa; C David James; V Peter Collins
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4309-13.
1991: A J Ekstrand; C David James; W K Cavenee; B Seliger; R F Pettersson; V Peter Collins
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo.
Cancer research 1991;51(8):2164-72.
1990: N Sugawa; A J Ekstrand; C David James; V Peter Collins
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8602-6.
1990: V P Collins; C David James
Molecular genetics of primary intracranial tumors.
Current opinion in oncology 1990;2(4):666-72.