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David James
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11
Sarkaria, Jann N.
10
Olson, Jeffrey
8
Frederick, Linda
8
Galanis, Evanthia
8
Jenkins, Robert
7
Carlson, Brett
7
Schroeder, Mark
6
Kitange, Gaspar
6
Giannini, Caterina
6
Eley, Greg
5
Grogan, Patrick
5
Scheithauer, Bernd
5
Smith, David
5
Wang, XY
5
O'Fallon, Judith
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All Publications
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2009: Hodgson J Graeme; Yeh Ru-Fang; Ray Amrita; Wang Nicholas J; Smirnov Ivan; Yu Mamie; Hariono Sujatmi; Silber Joachim; Feiler Heidi S; Gray Joe W; Spellman Paul T; Vandenberg Scott R; Berger Mitchel S; James C David
Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts.
Neuro-oncology 2009;11(5):477-87.
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2009: Carlson Brett L; Grogan Patrick T; Mladek Ann C; Schroeder Mark A; Kitange Gaspar J; Decker Paul A; Giannini Caterina; Wu Wenting; Ballman Karla A; James C David; Sarkaria Jann N
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
International journal of radiation oncology, biology, physics 2009;75(1):212-9.
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2009: Lu Kan V; Zhu Shaojun; Cvrljevic Anna; Huang Tiffany T; Sarkaria Shawn; Ahkavan David; Dang Julie; Dinca Eduard B; Plaisier Seema B; Oderberg Isaac; Lee Yohan; Chen Zugen; Caldwell Jeremy S; Xie Yongmin; Loo Joseph A; Seligson David; Chakravari Arnab; Lee Francis Y; Weinmann Roberto; Cloughesy Timothy F; Nelson Stanley F; Bergers Gabriele; Graeber Thomas; Furnari Frank B; James C David; Cavenee Webster K; Johns Terrance G; Mischel Paul S
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.
Cancer research 2009;69(17):6889-98.
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2009: Kitange Gaspar J; Carlson Brett L; Schroeder Mark A; Grogan Patrick T; Lamont Jeff D; Decker Paul A; Wu Wenting; James C David; Sarkaria Jann N
Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts.
Neuro-oncology 2009;11(3):281-91.
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2009: Kadoch Cigall; Dinca Eduard B; Voicu Ramona; Chen Lingjing; Nguyen Diana; Parikh Seema; Karrim Juliana; Shuman Marc A; Lowell Clifford A; Treseler Patrick A; James C David; Rubenstein James L
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):1989-97.
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2009: Prados Michael D; Chang Susan M; Butowski Nicholas; DeBoer Rebecca; Parvataneni Rupa; Carliner Hannah; Kabuubi Paul; Ayers-Ringler Jennifer; Rabbitt Jane; Page Margaretta; Fedoroff Anne; Sneed Penny K; Berger Mitchel S; McDermott Michael W; Parsa Andrew T; Vandenberg Scott; James C David; Lamborn Kathleen R; Stokoe David; Haas-Kogan Daphne A
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(4):579-84.
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2009: Sughrue Michael E; Yang Isaac; Kane Ari J; Rutkowski Martin J; Fang Shanna; James C David; Parsa Andrew T
Immunological considerations of modern animal models of malignant primary brain tumors.
Journal of translational medicine 2009;7():84.
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2009: Silber Joachim; James C David; Hodgson J Graeme
microRNAs in gliomas: small regulators of a big problem.
Neuromolecular medicine 2009;11(3):208-22.
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2009: Fan Qi-Wen; Cheng Christine; Knight Zachary A; Haas-Kogan Daphne; Stokoe David; James C David; McCormick Frank; Shokat Kevan M; Weiss William A
EGFR signals to mTOR through PKC and independently of Akt in glioma.
Science signaling 2009;2(55):ra4.
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2008: Yang Lin; Clarke Michelle J; Carlson Brett L; Mladek Ann C; Schroeder Mark A; Decker Paul; Wu Wenting; Kitange Gaspar J; Grogan Patrick T; Goble Jennie M; Uhm Joon; Galanis Evanthia; Giannini Caterina; Lane Heidi A; James C David; Sarkaria Jann N
PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3993-4001.
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2008: Sarkaria Jann N; Kitange Gaspar J; James C David; Plummer Ruth; Calvert Hilary; Weller Michael; Wick Wolfgang
Mechanisms of chemoresistance to alkylating agents in malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):2900-8.
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2008: Baia Gilson S; Dinca Eduard B; Ozawa Tomoko; Kimura Edna T; McDermott Michael W; James C David; VandenBerg Scott R; Lal Anita
An orthotopic skull base model of malignant meningioma.
Brain pathology (Zurich, Switzerland) 2008;18(2):172-9.
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2008: Chi John H; Panner Amith; Cachola Kristine; Crane Courtney A; Murray Joseph; Pieper Russell O; James C David; Parsa Andrew T
Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.
Journal of neurosurgery 2008;108(2):299-303.
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2008: Silber Joachim; Lim Daniel A; Petritsch Claudia; Persson Anders I; Maunakea Alika K; Yu Mamie; Vandenberg Scott R; Ginzinger David G; James C David; Costello Joseph F; Bergers Gabriele; Weiss William A; Alvarez-Buylla Arturo; Hodgson J Graeme
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.
BMC medicine 2008;6():14.
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2007: Liu Chunsheng; Sarkaria Jann N; Petell Cory A; Paraskevakou Georgia; Zollman Paula J; Schroeder Mark; Carlson Brett; Decker Paul A; Wu Wenting; James C David; Russell Stephen J; Galanis Evanthia
Combination of measles virus virotherapy and radiation therapy has synergistic activity in the treatment of glioblastoma multiforme.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7155-65.
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2007: Dinca Eduard B; Sarkaria Jann N; Schroeder Mark A; Carlson Brett L; Voicu Ramona; Gupta Nalin; Berger Mitchel S; James C David
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
Journal of neurosurgery 2007;107(3):610-6.
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2007: Paraskevakou Georgia; Allen Cory; Nakamura Takafumi; Zollman Paula; James C David; Peng Kah Whye; Schroeder Mark; Russell Stephen J; Galanis Evanthia
Epidermal growth factor receptor (EGFR)-retargeted measles virus strains effectively target EGFR- or EGFRvIII expressing gliomas.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(4):677-86.
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2007: Sarkaria Jann N; Yang Lin; Grogan Patrick T; Kitange Gaspar J; Carlson Brett L; Schroeder Mark A; Galanis Evanthia; Giannini Caterina; Wu Wenting; Dinca Eduard B; James C David
Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel.
Molecular cancer therapeutics 2007;6(3):1167-74.
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2006: Allen Cory; Vongpunsawad Sompong; Nakamura Takafumi; James C David; Schroeder Mark; Cattaneo Roberto; Giannini Caterina; Krempski James; Peng Kah-Whye; Goble Jenny M; Uhm Joon H; Russell Stephen J; Galanis Evanthia
Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity.
Cancer research 2006;66(24):11840-50.
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2006: Sarkaria Jann N; Carlson Brett L; Schroeder Mark A; Grogan Patrick; Brown Paul D; Giannini Caterina; Ballman Karla V; Kitange Gaspar J; Guha Abjahit; Pandita Ajay; James C David
Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2264-71.
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2005: Rao Ravi D; Mladek Ann C; Lamont Jeffrey D; Goble Jennie M; Erlichman Charles; James C David; Sarkaria Jann N
Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Neoplasia (New York, N.Y.) 2005;7(10):921-9.
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2005: Giannini Caterina; Sarkaria Jann N; Saito Atsushi; Uhm Joon H; Galanis Evanthia; Carlson Brett L; Schroeder Mark A; James C David
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme.
Neuro-oncology 2005;7(2):164-76.
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2005: Nakamura Takafumi; Peng Kah-Whye; Harvey Mary; Greiner Suzanne; Lorimer Ian A J; James Charles D; Russell Stephen J
Rescue and propagation of fully retargeted oncolytic measles viruses.
Nature biotechnology 2005;23(2):209-14.
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2004: Olson Jeffrey J; James C David; Lawson David; Hunter Steven; Tang Gordon; Billingsley Judy
Correlation of the response of recurrent malignant gliomas treated with interferon alpha with tumor interferon alpha gene content.
International journal of oncology 2004;25(2):419-27.
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2004: Pandita Ajay; Aldape Kenneth D; Zadeh Gelareh; Guha Abhijit; James C David
Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR.
Genes, chromosomes & cancer 2004;39(1):29-36.
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2003: Rao Ravi D; Uhm Joon H; Krishnan Sunil; James C David
Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.
Frontiers in bioscience : a journal and virtual library 2003;8():e270-80.
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2003: Dewald Gordon W; Brockman Stephanie R; Paternoster Sarah F; Bone Nancy D; O'Fallon Judith R; Allmer Cristine; James Charles D; Jelinek Diane F; Tschumper Renee C; Hanson Curtis A; Pruthi Rajiv K; Witzig Thomas E; Call Timothy G; Kay Neil E
Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia.
British journal of haematology 2003;121(2):287-95.
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2003: Park Soyeon; James C David
Lanthionine synthetase components C-like 2 increases cellular sensitivity to adriamycin by decreasing the expression of P-glycoprotein through a transcription-mediated mechanism.
Cancer research 2003;63(3):723-7.
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2003: Krishnan Sunil; Rao Ravi D; James C David; Sarkaria Jann N
Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas.
Frontiers in bioscience : a journal and virtual library 2003;8():e1-13.
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2002: Kurtkaya-Yapicier Ozlem; Scheithauer Bernd W; Hebrink Deanne; James Charles D
p53 in nonneoplastic central nervous system lesions: an immunohistochemical and genetic sequencing study.
Neurosurgery 2002;51(5):1246-54; discussion 1254-5.
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2002: Eley Greg D; Reiter Jill L; Pandita Ajay; Park Soyeon; Jenkins Robert B; Maihle Nita J; James C David
A chromosomal region 7p11.2 transcript map: its development and application to the study of EGFR amplicons in glioblastoma.
Neuro-oncology 2002;4(2):86-94.
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2001: Smith J S; Tachibana I; Passe S M; Huntley B K; Borell T J; Iturria N; O'Fallon J R; Schaefer P L; Scheithauer B W; James C D; Buckner J C; Jenkins R B
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.
Journal of the National Cancer Institute 2001;93(16):1246-56.
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2001: Shridhar V; Lee J; Pandita A; Iturria S; Avula R; Staub J; Morrissey M; Calhoun E; Sen A; Kalli K; Keeney G; Roche P; Cliby W; Lu K; Schmandt R; Mills G B; Bast R C; James C D; Couch F J; Hartmann L C; Lillie J; Smith D I
Genetic analysis of early- versus late-stage ovarian tumors.
Cancer research 2001;61(15):5895-904.
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2001: Giannini C; Hebrink D; Scheithauer B W; Dei Tos A P; James C D
Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma.
Neurogenetics 2001;3(3):159-62.
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2001: Erlichman C; Boerner S A; Hallgren C G; Spieker R; Wang X Y; James C D; Scheffer G L; Maliepaard M; Ross D D; Bible K C; Kaufmann S H
The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux.
Cancer research 2001;61(2):739-48.
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2001: Reiter J L; Threadgill D W; Eley G D; Strunk K E; Danielsen A J; Sinclair C S; Pearsall R S; Green P J; Yee D; Lampland A L; Balasubramaniam S; Crossley T D; Magnuson T R; James C D; Maihle N J
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.
Genomics 2001;71(1):1-20.
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2000: Gilhuis H J; Anderl K L; Boerman R H; Jeuken J M; James C D; Raffel C; Scheithauer B W; Jenkins R B
Comparative genomic hybridization of medulloblastomas and clinical relevance: eleven new cases and a review of the literature.
Clinical neurology and neurosurgery 2000;102(4):203-209.
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2000: Wu G J; Sinclair C S; Paape J; Ingle J N; Roche P C; James C D; Couch F J
17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes.
Cancer research 2000;60(19):5371-5.
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2000: Frederick L; Eley G; Wang X Y; James C D
Analysis of genomic rearrangements associated with EGRFvIII expression suggests involvement of Alu repeat elements.
Neuro-oncology 2000;2(3):159-63.
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2000: Biegel J A; Fogelgren B; Zhou J Y; James C D; Janss A J; Allen J C; Zagzag D; Raffel C; Rorke L B
Mutations of the INI1 rhabdoid tumor suppressor gene in medulloblastomas and primitive neuroectodermal tumors of the central nervous system.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2759-63.
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2000: Frederick L; Wang X Y; Eley G; James C D
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.
Cancer research 2000;60(5):1383-7.
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2000: Reiter J L; Eley G; James C D; Maihle N J
Correspondence re: S. Shintani et al., Intragenic mutation analysis of the human epidermal growth factor receptor (EGFR) gene in malignant human oral keratinocytes. Cancer Res., 59: 4142-4147, 1999.
Cancer research 2000;60(3):766-7.
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1999: Raffel C; Frederick L; O'Fallon J R; Atherton-Skaff P; Perry A; Jenkins R B; James C D
Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(12):4085-90.
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1999: James C D; Galanis E; Frederick L; Kimmel D W; Cunningham J M; Atherton-Skaff P J; O'Fallon J R; Jenkins R B; Buckner J C; Hunter S B; Olson J J; Scheithauer B W
Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation.
International journal of oncology 1999;15(3):547-53.
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1999: Alleyne C H; He J; Yang J; Hunter S B; Cotsonis G; James C D; Olson J J
Analysis of cyclin dependent kinase inhibitors in malignant astrocytomas.
International journal of oncology 1999;14(6):1111-6.
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1999: Couch F J; Wang X Y; Wu G J; Qian J; Jenkins R B; James C D
Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer.
Cancer research 1999;59(7):1408-11.
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1998: Eley G; Frederick L; Wang X Y; Smith D I; James C D
3' end structure and rearrangements of EGFR in glioblastomas.
Genes, chromosomes & cancer 1998;23(3):248-54.
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1998: Galanis E; Buckner J; Kimmel D; Jenkins R; Alderete B; O'Fallon J; Wang C H; Scheithauer B W; James C D
Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas.
International journal of oncology 1998;13(4):717-24.
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1998: Wang X Y; Smith D I; Liu W; James C D
GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR.
Genomics 1998;49(3):448-51.
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1998: Liu W; Smith D I; Rechtzigel K J; Thibodeau S N; James C D
Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations.
Nucleic acids research 1998;26(6):1396-400.
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1998: Olson J J; Barnett D; Yang J; Assietti R; Cotsonis G; James C D
Gene amplification as a prognostic factor in primary brain tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(1):215-22.
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1998: Wang X Y; Smith D I; Frederick L; James C D
Analysis of EGF receptor amplicons reveals amplification of multiple expressed sequences.
Oncogene 1998;16(2):191-5.
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1997: Liu W; James C D; Frederick L; Alderete B E; Jenkins R B
PTEN/MMAC1 mutations and EGFR amplification in glioblastomas.
Cancer research 1997;57(23):5254-7.
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1997: Raffel C; Jenkins R B; Frederick L; Hebrink D; Alderete B; Fults D W; James C D
Sporadic medulloblastomas contain PTCH mutations.
Cancer research 1997;57(5):842-5.
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1996: He J; Olson J J; Ekstrand A J; Serbanescu A; Yang J; Offermann M K; James C D
Transfection of IFNalpha in human glioblastoma cells and tumorigenicity in association with induction of PKR and OAS gene expression.
Journal of neurosurgery 1996;85(6):1085-90.
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1996: Petronio J; He J; Fults D; Pedone C; James C D; Allen J R
Common alternative gene alterations in adult malignant astrocytomas, but not in childhood primitive neuroectodermal tumors: P 16ink4 homozygous deletions and CDK4 gene amplifications.
Journal of neurosurgery 1996;84(6):1020-3.
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1996: James C D; Olson J J
Molecular genetics and molecular biology advances in brain tumors.
Current opinion in oncology 1996;8(3):188-95.
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1995: He J; Olson J J; James C D
Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines.
Cancer research 1995;55(21):4833-6.
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1995: Zhou M; Gu L; James C D; He J; Yeager A M; Smith S D; Findley H W
Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(7):1159-61.
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1995: Ekstrand A J; Liu L; He J; Hamid M L; Longo N; Collins V P; James C D
Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.
Oncogene 1995;10(7):1455-60.
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1995: Olson J J; James C D; Krisht A; Barnett D; Hunter S
Analysis of epidermal growth factor receptor gene amplification and alteration in stereotactic biopsies of brain tumors.
Neurosurgery 1995;36(4):740-6; discussion 747-8.
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1995: Hunter S B; Abbott K; Varma V A; Olson J J; Barnett D W; James C D
Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue.
Journal of neuropathology and experimental neurology 1995;54(1):57-64.
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1994: He J; Allen J R; Collins V P; Allalunis-Turner M J; Godbout R; Day R S; James C D
CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines.
Cancer research 1994;54(22):5804-7.
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1994: He J; Reifenberger G; Liu L; Collins V P; James C D
Analysis of glioma cell lines for amplification and overexpression of MDM2.
Genes, chromosomes & cancer 1994;11(2):91-6.
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1994: Ekstrand A J; Longo N; Hamid M L; Olson J J; Liu L; Collins V P; James C D
Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification.
Oncogene 1994;9(8):2313-20.
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1993: James C D; He J; Collins V P; Allalunis-Turner M J; Day R S
Localization of chromosome 9p homozygous deletions in glioma cell lines with markers constituting a continuous linkage group.
Cancer research 1993;53(16):3674-6.
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1992: Ekstrand A J; Sugawa N; James C D; Collins V P
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4309-13.
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1991: Ekstrand A J; James C D; Cavenee W K; Seliger B; Pettersson R F; Collins V P
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo.
Cancer research 1991;51(8):2164-72.
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1990: Sugawa N; Ekstrand A J; James C D; Collins V P
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8602-6.
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1990: Collins V P; James C D
Molecular genetics of primary intracranial tumors.
Current opinion in oncology 1990;2(4):666-72.
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