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Kim Janda
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40
Dickerson, Tobin
36
Wirsching, Peter
35
Lerner, Richard
25
Meijler, Michael
23
Kaufmann, Gunnar
22
Wentworth, Paul
15
Clapham, Bruce
13
Moss, Jason
12
Mee, Jenny
12
Hixon, Mark
12
Wentworth, Anita
12
Gao, Changshou
12
Zhou, Bin
11
Yamamoto, Noboru
11
Hoffman, Timothy
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All Publications
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2009: Lowery Colin A; Abe Takumi; Park Junguk; Eubanks Lisa M; Sawada Daisuke; Kaufmann Gunnar F; Janda Kim D
Revisiting AI-2 quorum sensing inhibitors: direct comparison of alkyl-DPD analogues and a natural product fimbrolide.
Journal of the American Chemical Society 2009;131(43):15584-5.
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2009: Lowery Colin A; Park Junguk; Gloeckner Christian; Meijler Michael M; Mueller Ryan S; Boshoff Helena I; Ulrich Ricky L; Barry Clifton E; Bartlett Douglas H; Kravchenko Vladimir V; Kaufmann Gunnar F; Janda Kim D
Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.
Journal of the American Chemical Society 2009;131(40):14473-9.
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2009: Salzameda Nicholas T; Barbieri Joseph T; Janda Kim D
Synthetic substrate for application in both high and low throughput assays for botulinum neurotoxin B protease inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(20):5848-50.
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2009: Capková Katerina; Salzameda Nicholas T; Janda Kim D
Investigations into small molecule non-peptidic inhibitors of the botulinum neurotoxins.
Toxicon : official journal of the International Society on Toxinology 2009;54(5):575-82.
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2009: Frederick Michael O; De Lamo Marin Sandra; Janda Kim D; Nicolaou K C; Dickerson Tobin J
Monoclonal antibodies with orthogonal azaspiracid epitopes.
Chembiochem : a European journal of chemical biology 2009;10(10):1625-9.
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2009: Moreno Amira Y; Janda Kim D
Immunopharmacotherapy: vaccination strategies as a treatment for drug abuse and dependence.
Pharmacology, biochemistry, and behavior 2009;92(2):199-205.
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2009: Fischer Audrey; Nakai Yuya; Eubanks Lisa M; Clancy Colin M; Tepp William H; Pellett Sabine; Dickerson Tobin J; Johnson Eric A; Janda Kim D; Montal Mauricio
Bimodal modulation of the botulinum neurotoxin protein-conducting channel.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1330-5.
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2009: Nakai Yuya; Tepp William H; Dickerson Tobin J; Johnson Eric A; Janda Kim D
Function-oriented synthesis applied to the anti-botulinum natural product toosendanin.
Bioorganic & medicinal chemistry 2009;17(3):1152-7.
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2009: Zhou Heyue; Zhou Bin; Pellett Sabine; Johnson Eric A; Janda Kim D
Selection and characterization of a human monoclonal neutralizing antibody for Clostridium Botulinum neurotoxin serotype B.
Bioorganic & medicinal chemistry letters 2009;19(3):662-4.
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2009: Treweek Jennifer B; Moreno Amira Y; Janda Kim D
SLEEPLESS-ness and insomnia in fruit flies.
Angewandte Chemie (International ed. in English) 2009;48(3):438-40.
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2008: Mayorov Alexander V; Amara Neri; Chang Jason Y; Moss Jason A; Hixon Mark S; Ruiz Diana I; Meijler Michael M; Zorrilla Eric P; Janda Kim D
Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(45):17487-92.
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2008: Treweek Jennifer B; Sun Chengzao; Mayorov Alexander V; Qi Longwu; Levy Coree L; Roberts Amanda J; Dickerson Tobin J; Janda Kim D
Prevention of drug-induced memory impairment by immunopharmacotherapy.
Journal of medicinal chemistry 2008;51(21):6866-75.
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2008: Park Junguk; Kaufmann Gunnar F; Bowen J Phillip; Arbiser Jack L; Janda Kim D
Solenopsin A, a venom alkaloid from the fire ant Solenopsis invicta, inhibits quorum-sensing signaling in Pseudomonas aeruginosa.
The Journal of infectious diseases 2008;198(8):1198-201.
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2008: Capková Katerina; Hixon Mark S; McAllister Laura A; Janda Kim D
Toward the discovery of potent inhibitors of botulinum neurotoxin A: development of a robust LC MS based assay operational from low to subnanomolar enzyme concentrations.
Chemical communications (Cambridge, England) 2008;(30):3525-7.
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2008: Park Junguk; Dickerson Tobin J; Janda Kim D
Major sperm protein as a diagnostic antigen for onchocerciasis.
Bioorganic & medicinal chemistry 2008;16(15):7206-9.
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2008: Lowery Colin A; Park Junguk; Kaufmann Gunnar F; Janda Kim D
An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues.
Journal of the American Chemical Society 2008;130(29):9200-1.
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2008: Lowery Colin A; Dickerson Tobin J; Janda Kim D
Interspecies and interkingdom communication mediated by bacterial quorum sensing.
Chemical Society reviews 2008;37(7):1337-46.
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2008: Kravchenko Vladimir V; Kaufmann Gunnar F; Mathison John C; Scott David A; Katz Alexander Z; Grauer David C; Lehmann Mandy; Meijler Michael M; Janda Kim D; Ulevitch Richard J
Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule.
Science (New York, N.Y.) 2008;321(5886):259-63.
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2008: Kaufmann Gunnar F; Park Junguk; Janda Kim D
Bacterial quorum sensing: a new target for anti-infective immunotherapy.
Expert opinion on biological therapy 2008;8(6):719-24.
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2008: Kaufmann Gunnar F; Park Junguk; Mee Jenny M; Ulevitch Richard J; Janda Kim D
The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone.
Molecular immunology 2008;45(9):2710-4.
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2008: Zhou Bin; Pellett Sabine; Tepp William H; Zhou Heyue; Johnson Eric A; Janda Kim D
Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects.
FEBS letters 2008;582(10):1526-31.
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2008: Yoneda Yoshiyuki; Steiniger Sebastian C J; Capková Katerina; Mee Jenny M; Liu Ying; Kaufmann Gunnar F; Janda Kim D
A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy.
Bioorganic & medicinal chemistry letters 2008;18(5):1632-6.
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2008: Debler Erik W; Kaufmann Gunnar F; Meijler Michael M; Heine Andreas; Mee Jenny M; Pljevaljcic Goran; Di Bilio Angel J; Schultz Peter G; Millar David P; Janda Kim D; Wilson Ian A; Gray Harry B; Lerner Richard A
Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science (New York, N.Y.) 2008;319(5867):1232-5.
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2008: Zarebski Laura M; Vaughan Kerrie; Sidney John; Peters Bjoern; Grey Howard; Janda Kim D; Casadevall Arturo; Sette Alessandro
Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.
Expert review of vaccines 2008;7(1):55-74.
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2008: Willis Bert; Eubanks Lisa M; Wood Malcolm R; Janda Kim D; Dickerson Tobin J; Lerner Richard A
Biologically templated organic polymers with nanoscale order.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1416-9.
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2008: Richardson Heather N; Zhao Yu; Fekete Eva M; Funk Cindy K; Wirsching Peter; Janda Kim D; Zorrilla Eric P; Koob George F
MPZP: a novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist.
Pharmacology, biochemistry, and behavior 2008;88(4):497-510.
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2008: Zhou Bin; Carney Charlotte; Janda Kim D
Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin.
Bioorganic & medicinal chemistry 2008;16(4):1903-13.
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2008: Willis Bert; Eubanks Lisa M; Dickerson Tobin J; Janda Kim D
The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison.
Angewandte Chemie (International ed. in English) 2008;47(44):8360-79.
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2007: Brogan Andrew P; Dickerson Tobin J; Janda Kim D
Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.
Chemical communications (Cambridge, England) 2007;(46):4952-4.
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2007: Capková Katerina; Yoneda Yoshiyuki; Dickerson Tobin J; Janda Kim D
Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(23):6463-6.
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2007: Park Junguk; Jagasia Reshma; Kaufmann Gunnar F; Mathison John C; Ruiz Diana I; Moss Jason A; Meijler Michael M; Ulevitch Richard J; Janda Kim D
Infection control by antibody disruption of bacterial quorum sensing signaling.
Chemistry & biology 2007;14(10):1119-27.
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2007: Zhou Heyue; Zhou Bin; Ma Hongzheng; Carney Charlotte; Janda Kim D
Selection and characterization of human monoclonal antibodies against Abrin by phage display.
Bioorganic & medicinal chemistry letters 2007;17(20):5690-2.
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2007: Xu Yang; Hixon Mark S; Dawson Philip E; Janda Kim D
Development of a FRET assay for monitoring of HIV gp41 core disruption.
The Journal of organic chemistry 2007;72(18):6700-7.
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2007: Ino Akira; Dickerson Tobin J; Janda Kim D
Positional linker effects in haptens for cocaine immunopharmacotherapy.
Bioorganic & medicinal chemistry letters 2007;17(15):4280-3.
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2007: Dickerson Tobin J; McKenzie Kathleen M; Hoyt Amanda S; Wood Malcolm R; Janda Kim D; Brenner Sydney B; Lerner Richard A
Phage escape libraries for checkmate analysis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12703-8.
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2007: Treweek Jennifer; Wee Sunmee; Koob George F; Dickerson Tobin J; Janda Kim D
Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11580-4.
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2007: Silvaggi Nicholas R; Boldt Grant E; Hixon Mark S; Kennedy Jack P; Tzipori Saul; Janda Kim D; Allen Karen N
Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain complexed with small-molecule inhibitors highlight active-site flexibility.
Chemistry & biology 2007;14(5):533-42.
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2007: Debler Erik W; Kaufmann Gunnar F; Kirchdoerfer Robert N; Mee Jenny M; Janda Kim D; Wilson Ian A
Crystal structures of a quorum-quenching antibody.
Journal of molecular biology 2007;368(5):1392-402.
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2007: Liu Ying; Steiniger Sebastian C J; Kim YoungSoo; Kaufmann Gunnar F; Felding-Habermann Brunhilde; Janda Kim D
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery.
Molecular pharmaceutics 2007;4(3):435-47.
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2007: Steiniger Sebastian C J; Altobell Laurence J; Zhou Bin; Janda Kim D
Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen.
Molecular immunology 2007;44(10):2749-55.
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2007: Xu Yang; Hixon Mark S; Yamamoto Noboru; McAllister Laura A; Wentworth Anita D; Wentworth Paul; Janda Kim D
Antibody-catalyzed anaerobic destruction of methamphetamine.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3681-6.
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2007: Brogan Andrew P; Eubanks Lisa M; Koob George F; Dickerson Tobin J; Janda Kim D
Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol.
Journal of the American Chemical Society 2007;129(12):3698-702.
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2007: Eubanks Lisa M; Dickerson Tobin J; Janda Kim D
Technological advancements for the detection of and protection against biological and chemical warfare agents.
Chemical Society reviews 2007;36(3):458-70.
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2007: McAllister Laura A; Hixon Mark S; Schwartz Roberta; Kubitz Diane S; Janda Kim D
Synthesis and application of a novel ligand for affinity chromatography based removal of endotoxin from antibodies.
Bioconjugate chemistry 2007;18(2):559-66.
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2007: De Lamo Marin Sandra; Xu Yang; Meijler Michael M; Janda Kim D
Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria.
Bioorganic & medicinal chemistry letters 2007;17(6):1549-52.
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2007: Eubanks Lisa M; Hixon Mark S; Jin Wei; Hong Sukwon; Clancy Colin M; Tepp William H; Baldwin Michael R; Malizio Carl J; Goodnough Michael C; Barbieri Joseph T; Johnson Eric A; Boger Dale L; Dickerson Tobin J; Janda Kim D
An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2602-7.
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2007: McKenzie Kathleen M; Mee Jenny M; Rogers Claude J; Hixon Mark S; Kaufmann Gunnar F; Janda Kim D
Identification and characterization of single chain anti-cocaine catalytic antibodies.
Journal of molecular biology 2007;365(3):722-31.
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2006: Rogers Claude J; Eubanks Lisa M; Dickerson Tobin J; Janda Kim D
Unexpected acetylcholinesterase activity of cocaine esterases.
Journal of the American Chemical Society 2006;128(48):15364-5.
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2006: Brogan Andrew P; Dickerson Tobin J; Janda Kim D
Enamine-based aldol organocatalysis in water: are they really "all wet"?
Angewandte Chemie (International ed. in English) 2006;45(48):8100-2.
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2006: Eubanks Lisa M; Rogers Claude J; Beuscher Albert E; Koob George F; Olson Arthur J; Dickerson Tobin J; Janda Kim D
A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Molecular pharmaceutics 2006;3(6):773-7.
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2006: Kravchenko Vladimir V; Kaufmann Gunnar F; Mathison John C; Scott David A; Katz Alexander Z; Wood Malcolm R; Brogan Andrew P; Lehmann Mandy; Mee Jenny M; Iwata Kazunori; Pan Qilin; Fearns Colleen; Knaus Ulla G; Meijler Michael M; Janda Kim D; Ulevitch Richard J
N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.
The Journal of biological chemistry 2006;281(39):28822-30.
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2006: Zorrilla Eric P; Iwasaki Shinichi; Moss Jason A; Chang Jason; Otsuji Jonathan; Inoue Koki; Meijler Michael M; Janda Kim D
Vaccination against weight gain.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(35):13226-31.
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2006: Kim Youngsoo; Lillo Antonietta M; Steiniger Sebastian C J; Liu Ying; Ballatore Carlo; Anichini Andrea; Mortarini Roberta; Kaufmann Gunnar F; Zhou Bin; Felding-Habermann Brunhilde; Janda Kim D
Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.
Biochemistry 2006;45(31):9434-44.
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2006: Boldt Grant E; Eubanks Lisa M; Janda Kim D
Identification of a botulinum neurotoxin A protease inhibitor displaying efficacy in a cellular model.
Chemical communications (Cambridge, England) 2006;(29):3063-5.
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2006: Dickerson Tobin J; Janda Kim D
The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication.
ACS chemical biology 2006;1(6):359-69.
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2006: Fu Zhuji; Chen Sheng; Baldwin Michael R; Boldt Grant E; Crawford Adam; Janda Kim D; Barbieri Joseph T; Kim Jung-Ja P
Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry 2006;45(29):8903-11.
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2006: Xu Yang; Lu Hong; Kennedy Jack P; Yan Xuxia; McAllister Laura A; Yamamoto Noboru; Moss Jason A; Boldt Grant E; Jiang Shibo; Janda Kim D
Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation.
Journal of combinatorial chemistry 2006;8(4):531-9.
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2006: Boldt Grant E; Kennedy Jack P; Hixon Mark S; McAllister Laura A; Barbieri Joseph T; Tzipori Saul; Janda Kim D
Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin a inhibitors.
Journal of combinatorial chemistry 2006;8(4):513-21.
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2006: Ma Hongzheng; Zhou Bin; Kim YoungSoo; Janda Kim D
A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A.
Toxicon : official journal of the International Society on Toxinology 2006;47(8):901-8.
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2006: Moss Jason A; Stokols Shula; Hixon Mark S; Ashley Fawn T; Chang Jason Y; Janda Kim D
Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers.
Biomacromolecules 2006;7(4):1011-6.
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2006: Boldt Grant E; Kennedy Jack P; Janda Kim D
Identification of a potent botulinum neurotoxin a protease inhibitor using in situ lead identification chemistry.
Organic letters 2006;8(8):1729-32.
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2006: McAllister Laura A; Hixon Mark S; Kennedy Jack P; Dickerson Tobin J; Janda Kim D
Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin.
Journal of the American Chemical Society 2006;128(13):4176-7.
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2006: Xu Yang; Shi Jin; Yamamoto Noboru; Moss Jason A; Vogt Peter K; Janda Kim D
A credit-card library approach for disrupting protein-protein interactions.
Bioorganic & medicinal chemistry 2006;14(8):2660-73.
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2006: Kaufmann Gunnar F; Sartorio Rafaella; Lee Sang-Hyeup; Mee Jenny M; Altobell Laurence J; Kujawa David P; Jeffries Emily; Clapham Bruce; Meijler Michael M; Janda Kim D
Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing.
Journal of the American Chemical Society 2006;128(9):2802-3.
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2006: Boldt Grant E; Dickerson Tobin J; Janda Kim D
Emerging chemical and biological approaches for the preparation of discovery libraries.
Drug discovery today 2006;11(3-4):143-8.
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2006: Zhu Xueyong; Dickerson Tobin J; Rogers Claude J; Kaufmann Gunnar F; Mee Jenny M; McKenzie Kathleen M; Janda Kim D; Wilson Ian A
Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure (London, England : 1993) 2006;14(2):205-16.
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2006: Wu Wenyuan; Luo Yunping; Sun Chengzao; Liu Yuan; Kuo Paul; Varga Janos; Xiang Rong; Reisfeld Ralph; Janda Kim D; Edgington Thomas S; Liu Cheng
Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms.
Cancer research 2006;66(2):970-80.
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2006: Zhang Ligang; Long Hai; Boldt Grant E; Janda Kim D; Schatz George C; Lewis Frederick D
Alpha- and beta-stilbenosides as base-pair surrogates in DNA hairpins.
Organic & biomolecular chemistry 2006;4(2):314-22.
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2005: Kim Youngsoo; Lillo Antonietta; Moss Jason A; Janda Kim D
A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide.
Molecular pharmaceutics 2005;2(6):528-35.
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2005: Shute Thomas S; Matsushita Masayuki; Dickerson Tobin J; La Clair James J; Janda Kim D; Burkart Michael D
A site-specific bifunctional protein labeling system for affinity and fluorescent analysis.
Bioconjugate chemistry 2005;16(6):1352-5.
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2005: Qi Longwu; Yamamoto Noboru; Meijler Michael M; Altobell Laurence J; Koob George F; Wirsching Peter; Janda Kim D
Delta9-tetrahydrocannabinol immunochemical studies: haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta9-tetrahydrocannabinol.
Journal of medicinal chemistry 2005;48(23):7389-99.
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2005: Dickerson Tobin J; Beuscher Albert E; Rogers Claude J; Hixon Mark S; Yamamoto Noboru; Xu Yang; Olson Arthur J; Janda Kim D
Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library.
Biochemistry 2005;44(45):14845-53.
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2005: Matsushita Hana; Yamamoto Noboru; Meijler Michael M; Wirsching Peter; Lerner Richard A; Matsushita Masayuki; Janda Kim D
Chiral sensing using a blue fluorescent antibody.
Molecular bioSystems 2005;1(4):303-6.
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2005: Matsushita Masayuki; Meijler Michael M; Wirsching Peter; Lerner Richard A; Janda Kim D
A blue fluorescent antibody-cofactor sensor for mercury.
Organic letters 2005;7(22):4943-6.
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2005: Eubanks Lisa M; Dickerson Tobin J; Janda Kim D
Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A.
FEBS letters 2005;579(24):5361-4.
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2005: McKenzie Kathleen M; Meijler Michael M; Lowery Colin A; Boldt Grant E; Janda Kim D
A furanosyl-carbonate autoinducer in cell-to-cell communication of V. harveyi.
Chemical communications (Cambridge, England) 2005;(38):4863-5.
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2005: Xu Yang; Yamamoto Noboru; Ruiz Diana I; Kubitz Diane S; Janda Kim D
Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies.
Bioorganic & medicinal chemistry letters 2005;15(19):4304-7.
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2005: Toker Jonathan D; Tremblay Martin R; Yli-Kauhaluoma Jari; Wentworth Anita D; Zhou Bin; Wentworth Paul; Janda Kim D
Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction.
The Journal of organic chemistry 2005;70(20):7810-5.
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2005: Carrera M Rocío A; Trigo José Manuel; Wirsching Peter; Roberts Amanda J; Janda Kim D
Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose.
Pharmacology, biochemistry, and behavior 2005;81(4):709-14.
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2005: Brogan Andrew P; Dickerson Tobin J; Boldt Grant E; Janda Kim D
Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10433-8.
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2005: Rogers Claude J; Mee Jenny M; Kaufmann Gunnar F; Dickerson Tobin J; Janda Kim D
Toward cocaine esterase therapeutics.
Journal of the American Chemical Society 2005;127(28):10016-7.
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2005: Dickerson Tobin J; Kaufmann Gunnar F; Janda Kim D
Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy.
Expert opinion on biological therapy 2005;5(6):773-81.
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2005: Lowery Colin A; McKenzie Kathleen M; Qi Longwu; Meijler Michael M; Janda Kim D
Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site.
Bioorganic & medicinal chemistry letters 2005;15(9):2395-8.
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2005: Rogers Claude J; Dickerson Tobin J; Brogan Andrew P; Janda Kim D
Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis.
The Journal of organic chemistry 2005;70(9):3705-8.
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2005: Kaufmann Gunnar F; Meijler Michael M; Sun Chengzao; Chen Da-Wei; Kujawa David P; Mee Jenny M; Hoffman Timothy Z; Wirsching Peter; Lerner Richard A; Janda Kim D
Enzymatic incorporation of an antibody-activated blue fluorophore into DNA.
Angewandte Chemie (International ed. in English) 2005;44(14):2144-8.
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2005: Reed Neal N; Dickerson Tobin J; Boldt Grant E; Janda Kim D
Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer.
The Journal of organic chemistry 2005;70(5):1728-31.
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2005: Meijler Michael M; Kaufmann Gunnar F; Qi Longwu; Mee Jenny M; Coyle Avery R; Moss Jason A; Wirsching Peter; Matsushita Masayuki; Janda Kim D
Fluorescent cocaine probes: a tool for the selection and engineering of therapeutic antibodies.
Journal of the American Chemical Society 2005;127(8):2477-84.
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2005: Moss Jason A; Lillo Antonietta; Kim Young Soo; Gao Changshou; Ditzel Henrik; Janda Kim D
A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide.
Journal of the American Chemical Society 2005;127(2):538-9.
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2005: Kaufmann Gunnar F; Sartorio Rafaella; Lee Sang-Hyeup; Rogers Claude J; Meijler Michael M; Moss Jason A; Clapham Bruce; Brogan Andrew P; Dickerson Tobin J; Janda Kim D
Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):309-14.
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2005: Dickerson Tobin J; Janda Kim D
Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy.
The AAPS journal 2005;7(3):E579-86.
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2004: Dickerson Tobin J; Reed Neal N; LaClair James J; Janda Kim D
A precipitator for the detection of thiophilic metals in aqua.
Journal of the American Chemical Society 2004;126(50):16582-6.
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2004: Lee Sang-Hyeup; Yoshida Kazuhiro; Matsushita Hana; Clapham Bruce; Koch Guido; Zimmermann Jürg; Janda Kim D
N-H insertion reactions of primary ureas: the synthesis of highly substituted imidazolones and imidazoles from diazocarbonyls.
The Journal of organic chemistry 2004;69(25):8829-35.
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2004: Felding-Habermann Brunhilde; Lerner Richard A; Lillo Antonietta; Zhuang Shufei; Weber Martin R; Arrues Sandra; Gao Changshou; Mao Shenlan; Saven Alan; Janda Kim D
Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17210-5.
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2004: Matsushita Hana; Lee Sang-Hyeup; Yoshida Kazuhiro; Clapham Bruce; Koch Guido; Zimmermann Jürg; Janda Kim D
N-h insertion reactions of Boc-amino acid amides: solution- and solid-phase synthesis of pyrazinones and pyrazines.
Organic letters 2004;6(24):4627-9.
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2004: Kim Young Soo; Moss Jason A; Janda Kim D
Biological tuning of synthetic tactics in solid-phase synthesis: application to A beta(1-42).
The Journal of organic chemistry 2004;69(22):7776-8.
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2004: Xu Yang; Yamamoto Noboru; Janda Kim D
Catalytic antibodies: hapten design strategies and screening methods.
Bioorganic & medicinal chemistry 2004;12(20):5247-68.
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2004: Dickerson Tobin J; Lovell Timothy; Meijler Michael M; Noodleman Louis; Janda Kim D
Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis.
The Journal of organic chemistry 2004;69(20):6603-9.
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2004: Carrera M Rocío A; Meijler Michael M; Janda Kim D
Cocaine pharmacology and current pharmacotherapies for its abuse.
Bioorganic & medicinal chemistry 2004;12(19):5019-30.
-
2004: Dickerson Tobin J; Yamamoto Noboru; Ruiz Diana I; Janda Kim D
Immunological consequences of methamphetamine protein glycation.
Journal of the American Chemical Society 2004;126(37):11446-7.
-
2004: Lee Sang-Hyeup; Matsushita Hana; Koch Guido; Zimmermann Jürg; Clapham Bruce; Janda Kim D
Smart cleavage reactions: the synthesis of an array of ureas from polymer-bound carbamates.
Journal of combinatorial chemistry 2004;6(5):822-7.
-
2004: Dickerson Tobin J; Yamamoto Noboru; Janda Kim D
Antibody-catalyzed oxidative degradation of nicotine using riboflavin.
Bioorganic & medicinal chemistry 2004;12(18):4981-7.
-
2004: Lillo Antonietta M; Sun Chengzao; Gao Changshou; Ditzel Henrik; Parrish Jay; Gauss Carla-Marie; Moss Jason; Felding-Habermann Brunhilde; Wirsching Peter; Boger Dale L; Janda Kim D
A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.
Chemistry & biology 2004;11(7):897-906.
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2004: Carrera M Rocio A; Kaufmann Gunnar F; Mee Jenny M; Meijler Michael M; Koob George F; Janda Kim D
Treating cocaine addiction with viruses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10416-21.
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2004: Lee Byoung Se; Mahajan Suresh; Clapham Bruce; Janda Kim D
Suspension ring-opening metathesis polymerization: the preparation of norbornene-based resins for application in organic synthesis.
The Journal of organic chemistry 2004;69(10):3319-29.
-
2004: Qi Longwu; Meijler Michael M; Lee Sang-Hyeup; Sun Chengzao; Janda Kim D
Solid-phase synthesis of anandamide analogues.
Organic letters 2004;6(10):1673-5.
-
2004: Meijler Michael M; Hom Louis G; Kaufmann Gunnar F; McKenzie Kathleen M; Sun Chengzao; Moss Jason A; Matsushita Masayuki; Janda Kim D
Synthesis and biological validation of a ubiquitous quorum-sensing molecule.
Angewandte Chemie (International ed. in English) 2004;43(16):2106-8.
-
2004: Ahn Jung-Mo; Wentworth Paul; Janda Kim D
Probing lipase/esterase libraries for lipid A hydrolases--discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein.
Chemical communications (Cambridge, England) 2004;(4):364-5.
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2004: Carrera M Rocío A; Ashley Jon A; Hoffman Timothy Z; Isomura Shigeki; Wirsching Peter; Koob George F; Janda Kim D
Investigations using immunization to attenuate the psychoactive effects of nicotine.
Bioorganic & medicinal chemistry 2004;12(3):563-70.
-
2004: Meijler Michael M; Matsushita Masayuki; Wirsching Peter; Janda Kim D
Development of immunopharmacotherapy against drugs of abuse.
Current drug discovery technologies 2004;1(1):77-89.
-
2003: Matsushita Masayuki; Yoshida Kazuhiro; Yamamoto Noboru; Wirsching Peter; Lerner Richard A; Janda Kim D
High-throughput screening by using a blue-fluorescent antibody sensor.
Angewandte Chemie (International ed. in English) 2003;42(48):5984-7.
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2003: Dickerson Tobin J; Tremblay Martin R; Hoffman Timothy Z; Ruiz Diana I; Janda Kim D
Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states.
Journal of the American Chemical Society 2003;125(50):15395-401.
-
2003: Wentworth Paul; Nieva Jorge; Takeuchi Cindy; Galve Roger; Wentworth Anita D; Dilley Ralph B; DeLaria Giacomo A; Saven Alan; Babior Bernard M; Janda Kim D; Eschenmoser Albert; Lerner Richard A
Evidence for ozone formation in human atherosclerotic arteries.
Science (New York, N.Y.) 2003;302(5647):1053-6.
-
2003: Chen Yanping; Gambs Celine; Abe Yoshito; Wentworth Paul; Janda Kim D
Total synthesis of the depsipeptide FR-901375.
The Journal of organic chemistry 2003;68(23):8902-5.
-
2003: Moss Jason A; Coyle Avery R; Ahn Jung Mo; Meijler Michael M; Offer John; Janda Kim D
Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody.
Journal of immunological methods 2003;281(1-2):143-8.
-
2003: Dickerson Tobin J; Janda Kim D
Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8182-7.
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2003: Meijler Michael M; Matsushita Masayuki; Altobell Laurence J; Wirsching Peter; Janda Kim D
A new strategy for improved nicotine vaccines using conformationally constrained haptens.
Journal of the American Chemical Society 2003;125(24):7164-5.
-
2003: Redwan El-Rashdy M; Larsen Nicholas A; Zhou Bin; Wirsching Peter; Janda Kim D; Wilson Ian A
Expression and characterization of a humanized cocaine-binding antibody.
Biotechnology and bioengineering 2003;82(5):612-8.
-
2003: Zhu Xueyong; Heine Andreas; Monnat Frédéric; Houk K N; Janda Kim D; Wilson Ian A
Structural basis for antibody catalysis of a cationic cyclization reaction.
Journal of molecular biology 2003;329(1):69-83.
-
2003: Gambs Céline; Dickerson Tobin J; Mahajan Suresh; Pasternack Laura B; Janda Kim D
High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins.
The Journal of organic chemistry 2003;68(9):3673-8.
-
2003: Sun Chengzao; Wirsching Peter; Janda Kim D
Enabling ScFvs as multi-drug carriers: a dendritic approach.
Bioorganic & medicinal chemistry 2003;11(8):1761-8.
-
2003: Lee Sang-Hyeup; Clapham Bruce; Koch Guido; Zimmermann Jürg; Janda Kim D
Solid-phase rhodium carbenoid N-H insertion reactions: the synthesis of a diverse array of indoles.
Journal of combinatorial chemistry 2003;5(2):188-96.
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2003: Gao Changshou; Mao Shenlan; Ronca Francesca; Zhuang Sufei; Quaranta Vito; Wirsching Peter; Janda Kim D
De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods.
Journal of immunological methods 2003;274(1-2):185-97.
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2003: Cannizzaro Carina E; Ashley Jon A; Janda K D; Houk K N
Experimental determination of the absolute enantioselectivity of an antibody-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity.
Journal of the American Chemical Society 2003;125(9):2489-506.
-
2003: Ahn Jung-Mo; Wentworth Paul; Janda Kim D
Soluble polymer-supported convergent parallel library synthesis.
Chemical communications (Cambridge, England) 2003;(4):480-1.
-
2003: Lee Sang-Hyeup; Clapham Bruce; Koch Guido; Zimmermann Jürg; Janda Kim D
Rhodium carbenoid N-H insertion reactions of primary ureas: solution and solid-phase synthesis of imidazolones.
Organic letters 2003;5(4):511-4.
-
2003: Wentworth Paul; Wentworth Anita D; Zhu Xueyong; Wilson Ian A; Janda Kim D; Eschenmoser Albert; Lerner Richard A
Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1490-3.
-
2003: Wang Qian; Raja Krishnaswami S; Janda Kim D; Lin Tianwei; Finn M G
Blue fluorescent antibodies as reporters of steric accessibility in virus conjugates.
Bioconjugate chemistry 2003;14(1):38-43.
-
2002: Wentworth Paul; McDunn Jonathan E; Wentworth Anita D; Takeuchi Cindy; Nieva Jorge; Jones Teresa; Bautista Cristina; Ruedi Julie M; Gutierrez Abel; Janda Kim D; Babior Bernard M; Eschenmoser Albert; Lerner Richard A
Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation.
Science (New York, N.Y.) 2002;298(5601):2195-9.
-
2002: Gao Changshou; Mao Shenlan; Ditzel Henrik J; Farnaes Lauge; Wirsching Peter; Lerner Richard A; Janda Kim D
A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library.
Bioorganic & medicinal chemistry 2002;10(12):4057-65.
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2002: Jones Lyn H; Altobell Laurence J; MacDonald Mary T; Boyle Nicholas A; Wentworth Paul; Lerner Richard A; Janda Kim D
Active immunization with a glycolipid transition state analogue protects against endotoxic shock.
Angewandte Chemie (International ed. in English) 2002;41(22):4241-4.
-
2002: Dickerson Tobin J; Janda Kim D
A previously undescribed chemical link between smoking and metabolic disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15084-8.
-
2002: Lee Kyung Joo; Mao Shenlan; Sun Chengzao; Gao Changshou; Blixt Ola; Arrues Sandra; Hom Louis G; Kaufmann Gunnar F; Hoffman Timothy Z; Coyle Avery R; Paulson James; Felding-Habermann Brunhilde; Janda Kim D
Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen.
Journal of the American Chemical Society 2002;124(42):12439-46.
-
2002: Dickerson Tobin J; Reed Neal N; Janda Kim D
Soluble polymers as scaffolds for recoverable catalysts and reagents.
Chemical reviews 2002;102(10):3325-44.
-
2002: Ahn Jung-Mo; Boyle Nicholas A; MacDonald Mary T; Janda Kim D
Peptidomimetics and peptide backbone modifications.
Mini reviews in medicinal chemistry 2002;2(5):463-73.
-
2002: Gao Changshou; Mao Shenlan; Kaufmann Gunnar; Wirsching Peter; Lerner Richard A; Janda Kim D
A method for the generation of combinatorial antibody libraries using pIX phage display.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12612-6.
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2002: Shimomura Osamu; Clapham Bruce; Spanka Carsten; Mahajan Suresh; Janda Kim D
Application of microgels as polymer supports for organic synthesis: preparation of a small phthalide library, a scavenger, and a borohydride reagent.
Journal of combinatorial chemistry 2002;4(5):436-41.
-
2002: Sun Chengzao; Wirsching Peter; Janda Kim D
Syntheses of dendritic linkers containing chlorambucil residues for the preparation of antibody-multidrug immunoconjugates.
Bioorganic & medicinal chemistry letters 2002;12(16):2213-5.
-
2002: Reed Neal N; Delgado Mercedes; Hereford Kristina; Clapham Bruce; Janda Kim D
Preparation of soluble and insoluble polymer supported IBX reagents.
Bioorganic & medicinal chemistry letters 2002;12(15):2047-9.
-
2002: Boyle Nicholas A; Janda Kim D
Formats for combinatorial synthesis: solid-phase, liquid-phase and surface.
Current opinion in chemical biology 2002;6(3):339-46.
-
2002: Delgado Mercedes; Lee Kyung Joo; Altobell Lawrence; Spanka Carsten; Wentworth Paul; Janda Kim D
A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity.
Journal of the American Chemical Society 2002;124(18):4946-7.
-
2002: Spanka Carsten; Clapham Bruce; Janda Kim D
Preparation of new microgel polymers and their application as supports in organic synthesis.
The Journal of organic chemistry 2002;67(9):3045-50.
-
2002: Spanka Carsten; Wentworth Paul; Janda Kim D
Developing soluble polymers for high-throughput synthetic chemistry.
Combinatorial chemistry & high throughput screening 2002;5(3):233-40.
-
2002: Kim Geun Tae; Wenz Marion; Park Jong Il; Hasserodt Jens; Janda Kim D
Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies.
Bioorganic & medicinal chemistry 2002;10(5):1249-62.
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2002: Zhou Bin; Wirsching Peter; Janda Kim D
Human antibodies against spores of the genus Bacillus: a model study for detection of and protection against anthrax and the bioterrorist threat.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5241-6.
-
2002: Isomura Shigeki; Hoffman Timothy Z; Wirsching Peter; Janda Kim D
Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration.
Journal of the American Chemical Society 2002;124(14):3661-8.
-
2002: Dickerson Tobin J; Janda Kim D
Aqueous aldol catalysis by a nicotine metabolite.
Journal of the American Chemical Society 2002;124(13):3220-1.
-
2002: Matsushita Masayuki; Janda Kim D
Histidine kinases as targets for new antimicrobial agents.
Bioorganic & medicinal chemistry 2002;10(4):855-67.
-
2002: Isomura Shigeki; Ashley Jon A; Wirsching Peter; Janda Kim D
Antibody-catalyzed cleavage of the D-Ala-D-Lac depsipeptide: an immunological approach to the problem of vancomycin resistance.
Bioorganic & medicinal chemistry letters 2002;12(6):861-4.
-
2002: Reger Thomas S; Janda Kim D
Parallel suspension polymerization for high-throughput resin synthesis.
Bioorganic & medicinal chemistry letters 2002;12(6):837-40.
-
2002: Delgado Mercedes; Spanka Carsten; Kerwin Lisa D; Wentworth Paul; Janda Kim D
A tunable hydrogel for encapsulation and controlled release of bioactive proteins.
Biomacromolecules 2002;3(2):262-71.
-
2002: Nicholas Kenneth M; Wentworth Paul; Harwig Curtis W; Wentworth Anita D; Shafton Asher; Janda Kim D
A cofactor approach to copper-dependent catalytic antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2648-53.
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2001: Kozlov I A; Mao S; Xu Y; Huang X; Lee L; Sears P S; Gao C; Coyle A R; Janda K D; Wong C H
Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates.
Chembiochem : a European journal of chemical biology 2001;2(10):741-6.
-
2001: Brümmer O; Hoffman T Z; Janda K D
Metalloantibodies: mercury(II)-dependent acyl transferases.
Bioorganic & medicinal chemistry 2001;9(9):2253-7.
-
2001: Wentworth P; Jones L H; Wentworth A D; Zhu X; Larsen N A; Wilson I A; Xu X; Goddard W A; Janda K D; Eschenmoser A; Lerner R A
Antibody catalysis of the oxidation of water.
Science (New York, N.Y.) 2001;293(5536):1806-11.
-
2001: Córdova A; Janda K D
Synthesis and catalytic antibody functionalization of dendrimers.
Journal of the American Chemical Society 2001;123(34):8248-59.
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2001: Córdova A; Tremblay M R; Clapham B; Janda K D
A sequential application of kinetic resolution and polymer-supported scavenging for the isolation of chiral secondary alcohols.
The Journal of organic chemistry 2001;66(16):5645-8.
-
2001: Larsen N A; Zhou B; Heine A; Wirsching P; Janda K D; Wilson I A
Crystal structure of a cocaine-binding antibody.
Journal of molecular biology 2001;311(1):9-15.
-
2001: Clapham B; Spanka C; Janda K D
Solid-phase rhodium carbenoid reactions: an N-H insertion route to a diverse series of oxazoles.
Organic letters 2001;3(14):2173-6.
-
2001: Dickerson T J; Reed N N; Janda K D
Regio-reactive resin: a platform for orthogonal loading using the polymer backbone and cross-linker.
Bioorganic & medicinal chemistry letters 2001;11(12):1507-9.
-
2001: Isomura S; Wirsching P; Janda K D
An immunotherapeutic program for the treatment of nicotine addiction: hapten design and synthesis.
The Journal of organic chemistry 2001;66(12):4115-21.
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2001: Jones L H; Harwig C W; Wentworth P; Simeonov A; Wentworth A D; Py S; Ashley J A; Lerner R A; Janda K D
Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism.
Journal of the American Chemical Society 2001;123(15):3607-8.
-
2001: Brümmer O; La Clair J J; Janda K D
Practical screening of mercury contamination in fish tissue.
Bioorganic & medicinal chemistry 2001;9(4):1067-71.
-
2001: Córdova A; Janda K D
A highly chemo- and stereoselective synthesis of beta-keto esters via a polymer-supported lipase catalyzed transesterfication.
The Journal of organic chemistry 2001;66(5):1906-9.
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2001: Chen D W; Beuscher A E; Stevens R C; Wirsching P; Lerner R A; Janda K D
Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies.
The Journal of organic chemistry 2001;66(5):1725-32.
-
2001: Clapham B; Cho C W; Janda K D
A polymer-supported proline-based diamine catalyst for the kinetic resolution of racemic secondary alcohols.
The Journal of organic chemistry 2001;66(3):868-73.
-
2001: Carrera M R; Ashley J A; Wirsching P; Koob G F; Janda K D
A second-generation vaccine protects against the psychoactive effects of cocaine.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1988-92.
-
2001: Matsushita M; Hoffman T Z; Ashley J A; Zhou B; Wirsching P; Janda K D
Cocaine catalytic antibodies: the primary importance of linker effects.
Bioorganic & medicinal chemistry letters 2001;11(2):87-90.
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2001: Toy P H; Reger T S; Garibay P; Garno J C; Malikayil J A; Liu G; Janda K D
Polytetrahydrofuran cross-linked polystyrene resins for solid-phase organic synthesis.
Journal of combinatorial chemistry 2001;3(1):117-24.
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2000: López-Pelegrín J A; Wentworth P; Sieber F; Metz W A; Janda K D
Soluble polymer-supported chemoenzymatic synthesis of the C(21)-C(27) fragment of the bryostatins.
The Journal of organic chemistry 2000;65(25):8527-31.
-
2000: Tremblay M R; Wentworth P; Lee G E; Janda K D
Parallel solid-phase synthesis and structural characterization of a library of highly substituted chiral 1,3-oxazolidines.
Journal of combinatorial chemistry 2000;2(6):698-709.
-
2000: Vaino A R; Janda K D
Solid-phase organic synthesis: a critical understanding of the resin.
Journal of combinatorial chemistry 2000;2(6):579-96.
-
2000: Simeonov A; Matsushita M; Juban E A; Thompson E H; Hoffman T Z; Beuscher A E; Taylor M J; Wirsching P; Rettig W; McCusker J K; Stevens R C; Millar D P; Schultz P G; Lerner R A; Janda K D
Blue-fluorescent antibodies.
Science (New York, N.Y.) 2000;290(5490):307-13.
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2000: Wentworth A D; Jones L H; Wentworth P; Janda K D; Lerner R A
Antibodies have the intrinsic capacity to destroy antigens.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10930-5.
-
2000: Reed N N; Janda K D
A one-step synthesis of monoprotected polyethylene glycol ethers.
The Journal of organic chemistry 2000;65(18):5843-5.
-
2000: Brummer O; Clapham B; Janda K D
Recent developments and applications of polymer-supported reagents in synthetic organic chemistry.
Current opinion in drug discovery & development 2000;3(4):462-73.
-
2000: Toy P H; Reger T S; Janda K D
Soluble polymer bound cleavage reagents: a multipolymer strategy for the cleavage of tertiary amines from REM resin.
Organic letters 2000;2(15):2205-7.
-
2000: Vaino A R; Goodin D B; Janda K D
Investigating resins for solid phase organic synthesis: the relationship between swelling and microenvironment as probed by EPR and fluorescence spectroscopy.
Journal of combinatorial chemistry 2000;2(4):330-6.
-
2000: Vaino A R; Janda K D
Euclidean shape-encoded combinatorial chemical libraries.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):7692-6.
-
2000: Hasserodt J; Janda K D; Lerner R A
A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities.
Bioorganic & medicinal chemistry 2000;8(5):995-1003.
-
2000: Harwig C W; Hoffman T Z; Wentworth A D; Janda K D
A one-pot multistep approach to alpha-azido-phosphonate and phosphonothioate diesters: key intermediates in the synthesis of haptens for the generation of antibody ligases.
Bioorganic & medicinal chemistry letters 2000;10(9):915-8.
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2000: Carrera M R; Ashley J A; Zhou B; Wirsching P; Koob G F; Janda K D
Cocaine vaccines: antibody protection against relapse in a rat model.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6202-6.
-
2000: Wentworth A D; Wentworth P; Mansoor U F; Janda K D
A soluble polymer-supported triflating reagent: a high-throughput synthetic approach to aryl and enol triflates.
Organic letters 2000;2(4):477-80.
-
2000: Janda K D
New directions in immunopharmacotherapy.
Ernst Schering Research Foundation workshop 2000;(32):315-46.
-
1999: Lee K J; Angulo A; Ghazal P; Janda K D
Soluble-polymer supported synthesis of a prostanoid library: identification of antiviral activity.
Organic letters 1999;1(11):1859-62.
-
1999: Sieber F; Wentworth P; Janda K D
Exploring the scope of poly(ethylene glycol) (PEG) as a soluble polymer matrix for the Stille cross-coupling reaction.
Journal of combinatorial chemistry 1999;1(6):540-6.
-
1999: Córdova A; Reed N N; Ashley J A; Janda K D
Convenient synthesis of L-proline benzyl ester.
Bioorganic & medicinal chemistry letters 1999;9(21):3119-22.
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1999: Spivak D A; Hoffman T Z; Moore A H; Taylor M J; Janda K D
A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis.
Bioorganic & medicinal chemistry 1999;7(6):1145-50.
-
1999: Mao S; Gao C; Lo C H; Wirsching P; Wong C H; Janda K D
Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6953-8.
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1999: Gao C; Mao S; Lo C H; Wirsching P; Lerner R A; Janda K D
Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6025-30.
-
1999: Berg T; Simeonov A; Janda K D
A combined parallel synthesis and screening of macrocyclic lanthanide complexes for the cleavage of phospho di- and triesters and double-stranded DNA.
Journal of combinatorial chemistry 1999;1(1):96-100.
-
1998: Zhao X Y; Janda K D
Soluble polymer traceless linker investigations: solvent effects on the desulfonylation of polyethylene glycol (PEG) substituted aryl alkyl sulfones with sodium amalgam.
Bioorganic & medicinal chemistry letters 1998;8(18):2439-42.
-
1998: Hori M; Gravert D J; Wentworth P; Janda K D
Investigating highly crosslinked macroporous resins for solid-phase synthesis.
Bioorganic & medicinal chemistry letters 1998;8(17):2363-8.
-
1998: Berg T; Vandersteen A M; Janda K D
High-throughput synthesis and direct screening for the discovery of novel hydrolytic metal complexes.
Bioorganic & medicinal chemistry letters 1998;8(10):1221-4.
-
1998: Wentworth P; Liu Y; Wentworth A D; Fan P; Foley M J; Janda K D
A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):5971-5.
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1998: Heine A; Stura E A; Yli-Kauhaluoma J T; Gao C; Deng Q; Beno B R; Houk K N; Janda K D; Wilson I A
An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science (New York, N.Y.) 1998;279(5358):1934-40.
-
1998: Wentworth P; Janda K D
Catalytic antibodies.
Current opinion in chemical biology 1998;2(1):138-44.
-
1998: Han H; Yoon J; Janda K D
Investigations of azapeptides as mimetics of Leu-enkephalin.
Bioorganic & medicinal chemistry letters 1998;8(1):117-20.
-
1997: Gao C; Lin C H; Lo C H; Mao S; Wirsching P; Lerner R A; Janda K D
Making chemistry selectable by linking it to infectivity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11777-82.
-
1997: Lin C H; Hoffman T Z; Wirsching P; Barbas C F; Janda K D; Lerner R A
On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11773-6.
-
1997: Gravert D J; Janda K D
Synthesis on soluble polymers: new reactions and the construction of small molecules.
Current opinion in chemical biology 1997;1(1):107-13.
-
1997: Janda K D; Lo L C; Lo C H; Sim M M; Wang R; Wong C H; Lerner R A
Chemical selection for catalysis in combinatorial antibody libraries.
Science (New York, N.Y.) 1997;275(5302):945-8.
-
1996: Vandersteen A M; Han H; Janda K D
Liquid-phase combinatorial synthesis: in search of small-molecule enzyme mimics.
Molecular diversity 1996;2(1-2):89-96.
-
1996: Yli-Kauhaluoma J T; Janda K D
Catalytic antibodies: the rerouting of chemical reactions. Towards electrophilic aromatic substitution by carbon dioxide.
Annals of the New York Academy of Sciences 1996;799():26-31.
-
1996: Gravert D J; Janda K D
Developing small-molecule libraries for drug discovery.
Trends in biotechnology 1996;14(4):110-2.
-
1996: Li T; Janda K D; Lerner R A
Cationic cyclopropanation by antibody catalysis.
Nature 1996;379(6563):326-7.
-
1996: Lerner R A; Barbas C F; Janda K D
Making enzymes.
Harvey lectures 1996;92():1-40.
-
1996: Janda K D; Han H
Combinatorial chemistry: a liquid-phase approach.
Methods in enzymology 1996;267():234-47.
-
1995: Wirsching P; Ashley J A; Lo C H; Janda K D; Lerner R A
Reactive immunization.
Science (New York, N.Y.) 1995;270(5243):1775-82.
-
1995: Carrera M R; Ashley J A; Parsons L H; Wirsching P; Koob G F; Janda K D
Suppression of psychoactive effects of cocaine by active immunization.
Nature 1995;378(6558):727-30.
-
1995: Han H; Wolfe M M; Brenner S; Janda K D
Liquid-phase combinatorial synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6419-23.
-
1995: Fenniri H; Janda K D; Lerner R A
Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical bonds.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2278-82.
-
1995: Lerner R A; Janda K D
Catalytic antibodies: evolution of protein function in real time.
EXS 1995;73():121-38.
-
1994: Erb E; Janda K D; Brenner S
Recursive deconvolution of combinatorial chemical libraries.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11422-6.
-
1994: Janda K D
Tagged versus untagged libraries: methods for the generation and screening of combinatorial chemical libraries.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10779-85.
-
1994: Yli-Kauhaluoma J; Janda K D
Twisted alpha-keto amides as transition-state analogues for acyl-transfer reactions: synthesis of the immunoconjugates.
Bioorganic & medicinal chemistry 1994;2(6):521-8.
-
1994: Li T; Janda K D; Ashley J A; Lerner R A
Antibody catalyzed cationic cyclization.
Science (New York, N.Y.) 1994;264(5163):1289-93.
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1994: Janda K D; Lo C H; Li T; Barbas C F; Wirsching P; Lerner R A
Direct selection for a catalytic mechanism from combinatorial antibody libraries.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2532-6.
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1993: Gouverneur V E; Houk K N; de Pascual-Teresa B; Beno B; Janda K D; Lerner R A
Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis.
Science (New York, N.Y.) 1993;262(5131):204-8.
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1993: Janda K D; Shevlin C G; Lerner R A
Antibody catalysis of a disfavored chemical transformation.
Science (New York, N.Y.) 1993;259(5094):490-3.
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1991: Wirsching P; Ashley J A; Benkovic S J; Janda K D; Lerner R A
An unexpectedly efficient catalytic antibody operating by ping-pong and induced fit mechanisms.
Science (New York, N.Y.) 1991;252(5006):680-5.
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1991: Kang A S; Barbas C F; Janda K D; Benkovic S J; Lerner R A
Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4363-6.
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