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In-Jin Jang

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Sung Eun Kim; Seunghwan Lee; Jin A Sohn; Seo Hyun Yoon; Kyung-Sang Yu; Joo-Youn Cho; In-Jin Jang; Bo-Hyung Kim; Han-Suk Kim; Kyoung Soo Lim
Population pharmacokinetics of theophylline in premature korean infants.
Min-Gul Kim; Kyoung Soo Lim; Sang-Goo Shin; Kyung-Sang Yu; In-Jin Jang; Bo-Hyung Kim; Jung-Ryul Kim; Joo-Youn Cho
The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin.
Donghoon Shin; Sang-Goo Shin; In-Jin Jang; Seunghwan Lee; Kyoung Soo Lim; Joong Shin Park; Kyung-Sang Yu
Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women.

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2013: Sung Eun Kim; Seunghwan Lee; Jin A Sohn; Seo Hyun Yoon; Kyung-Sang Yu; Joo-Youn Cho; In-Jin Jang; Bo-Hyung Kim; Han-Suk Kim; Kyoung Soo Lim
Population pharmacokinetics of theophylline in premature korean infants.
Therapeutic drug monitoring 2013;35(3):338-44.
2013: Min-Gul Kim; Kyoung Soo Lim; Sang-Goo Shin; Kyung-Sang Yu; In-Jin Jang; Bo-Hyung Kim; Jung-Ryul Kim; Joo-Youn Cho
The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin.
Current medical research and opinion 2013;29(6):685-93.
2013: Donghoon Shin; Sang-Goo Shin; In-Jin Jang; Seunghwan Lee; Kyoung Soo Lim; Joong Shin Park; Kyung-Sang Yu
Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women.
Contraception 2013;87(6):750-5.
2013: Euitae Kim; Ji Who Kim; Jae Sung Lee; Sang-Goo Shin; Federico E Turkheimer; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jun Soo Kwon
The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18) F]FDG imaging study with aripiprazole.
Psychopharmacology 2013;227(2):221-9.
2013: Kwang-Hee Shin; Sang-Goo Shin; Seo-Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Sei-Eun Kim; Tae-Eun Kim; Kyoung Soo Lim; Kyung-Mi Park; Kyung-Sang Yu
Pharmacokinetic and pharmacodynamic properties of a new long-acting granulocyte colony-stimulating factor (HM10460A) in healthy volunteers.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2013;27(2):149-58.
2013: Bora Kim; Seunghwan Lee; Kyoung Soo Lim; Ju-Yeon Moon; Hyang Hee Yang; Seo Hyun Yoon; Kyung-Sang Yu; Man Ho Choi; In-Jin Jang; Joo-Youn Cho
Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers.
Journal of proteome research 2013;12(3):1359-68.
2013: Hyeong-Seok Lim; Yook-Hwan Noh; Hyun Soo Park; Su Jin Kim; Byung Chul Lee; In-Jin Jang; Seok-Joon Jin; Soohyeon Kim; Sang Eun Kim
Exploration of optimal dosing regimens of haloperidol, a D2 Antagonist, via modeling and simulation analysis in a D2 receptor occupancy study.
Pharmaceutical research 2013;30(3):683-93.
2013: Jung Won Kim; Tae-Eun Kim; Min Goo Lee; Kyoung Soo Lim; Sang-Goo Shin; Im-Sook Song; SoJeong Yi; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Kyung-Sang Yu
Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin.
Journal of clinical pharmacology 2013;53(1):75-81.
2013: Hyewon Jeon; Tsutomu Kotegawa; SeungHwan Lee; Kyoichi Ohashi; Sang-Goo Shin; Seo Hyun Yoon; Kyung-Sang Yu; Joo-Youn Cho; Ichiro Ieiri; In-Jin Jang; Kyoung Soo Lim
Apple juice greatly reduces systemic exposure to atenolol.
British journal of clinical pharmacology 2013;75(1):172-9.
2012: Bo-Hyung Kim; Jung-Ryul Kim; Kyoung Soo Lim; Hyun-Suk Shin; Sang-Goo Shin; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Kyung-Sang Yu
Comparative pharmacokinetics/pharmacodynamics of clopidogrel besylate and clopidogrel bisulfate in healthy Korean subjects.
Clinical drug investigation 2012;32(12):817-26.
2012: Min Kyu Park; Kwang-Hee Shin; Sang-Goo Shin; So-Jeong Yi; Joo-Youn Cho; Hye-Kyung Han; In-Jin Jang; Tae-Eun Kim; Kyoung Soo Lim; Kyung-Sang Yu
Reduced valproic acid serum concentrations due to drug interactions with carbapenem antibiotics: overview of 6 cases.
Therapeutic drug monitoring 2012;34(5):599-603.
2012: Tae Eun Kim; Kyoung Soo Lim; Min Kyu Park; Sang-Goo Shin; Seo-Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Kyung-Sang Yu
Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study.
Clinical therapeutics 2012;34(9):1986-98.
2012: Namyi Gu; In-Jin Jang; JaeWoo Kim; Tae Eun Kim; Bongyong Lee; Kyoung Soo Lim; Kwang-Hee Shin; Sang-Goo Shin; Kyung-Sang Yu
Assessment of the effect of mirodenafil on the hemodynamics of healthy male Korean volunteers administered tamsulosin: a randomized, double-blind, placebo-controlled, 2-period crossover study.
Clinical therapeutics 2012;34(9):1929-39.
2012: Namyi Gu; In-Jin Jang; Bo-Hyung Kim; Sung Eun Kim; Kyoung Soo Lim; Won Seok Nam; Sang-Goo Shin; Seo Hyun Yoon; Joo-Youn Cho; Kyung-Sang Yu
The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy Korean male volunteers: a one-sequence, two-period crossover clinical trial.
Clinical therapeutics 2012;34(7):1592-600.
2012: Donghoon Shin; Sang-Goo Shin; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Tae-Eun Kim; Kyung-Sang Yu
Assessment of the pharmacokinetics of co-administered metformin and lobeglitazone, a thiazolidinedione antihyperglycemic agent, in healthy subjects.
Current medical research and opinion 2012;28(7):1213-20.
2012: SoJeong Yi; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Sung Eun Kim; Kyoung Soo Lim; Min-Kyu Park; Sang-Goo Shin; Kyung-Sang Yu
Comparative pharmacokinetics of HD203, a biosimilar of etanercept, with marketed etanercept (Enbrel®): a double-blind, single-dose, crossover study in healthy volunteers.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2012;26(3):177-84.
2012: Tae-Eun Kim; Prafull Mistry; Jeffrey Price; Donghoon Shin; Yong-Ju Chung; In-Jin Jang; Kyu-Pyo Kim; Kyung-Sang Yu
Assessment of the analgesic effect of remifentanil using three pain models in healthy Korean volunteers: a randomized, controlled study.
Basic & clinical pharmacology & toxicology 2012;110(6):518-23.
2012: Ji Won Lee; Seung Hwan Lee; Kyung Duk Park; Hee Young Shin; Sang Hoon Song; Kyung-Sang Yu; Yen Ju Yuk; Eun Jong Han; In-Jin Jang; Mi Kyoung Jang; Hyoung Jin Kang; Hyery Kim; Nam Hee Kim; Hyo Seop Ahn
Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(6):944-50.
2012: SeungHwan Lee; Kyoung Soo Lim; Sang-Goo Shin; Namyi Gu; In-Jin Jang; Bo-Hyung Kim; Kyung-Sang Yu
Pharmacokinetic and pharmacodynamic properties of the calcimimetic agent cinacalcet (KRN1493) in healthy male Korean subjects: a randomized, open-label, single ascending-dose, parallel-group study.
Clinical therapeutics 2012;34(5):1160-9.
2012: Sojeong Yi; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Hyewon Jeon; Sang-Goo Shin; Kyung-Sang Yu
Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men.
Journal of cardiovascular pharmacology 2012;59(4):315-22.
2012: Kwang-Hee Shin; Bo Yeun Yang; Seo-Hyun Yoon; In-Jin Jang; Jae-Min Jung; Ji Who Kim; wu gang; Jae Sung Lee; Yun-Sang Lee; Kyoung Soo Lim; Kyung-Sang Yu
A positron emission tomography microdosing study with sertraline in healthy volunteers.
International journal of clinical pharmacology and therapeutics 2012;50(3):224-32.
2012: Tae Eun Kim; Kyung-Mi Park; Sang-Goo Shin; Seo Hyun Yoon; Joo-Youn Cho; Namyi Gu; In-Jin Jang; Kyung-Sang Yu
Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies.
Clinical therapeutics 2012;34(2):482-94.
2012: Kyu-Pyo Kim; Kyoung Soo Lim; Hyun-Suk Shin; Sang-Goo Shin; Joo-Youn Cho; In-Jin Jang; Bo-Hyung Kim; Kyung-Sang Yu
Pharmacokinetics of a fixed-dose glimepiride/sustained-release metformin combination.
International journal of clinical pharmacology and therapeutics 2012;50(2):142-9.
2012: Sung Eun Kim; Willi Cawello; Jan-Peer Elshoff; Andreas Fitchner; Namyi Gu; In-Jin Jang; Bo-Hyung Kim; Kyung-Sang Yu
Pharmacokinetics of lacosamide in healthy korean male volunteers.
Pharmacology 2012;89(3-4):172-8.
2011: Jung Won Kim; Hyun-Suk Shin; Kwang-Hee Shin; Sang-Goo Shin; Sojeong Yi; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Dal-Hyun Kim; Jung-Ryul Kim; Kyung-Sang Yu
Tolerability and pharmacokinetics of lobeglitazone (CKD-501), a peroxisome proliferator-activated receptor-γ agonist: a single- and multiple-dose, double-blind, randomized control study in healthy male Korean subjects.
Clinical therapeutics 2011;33(11):1819-30.
2011: Kwang-Hee Shin; Sang-Goo Shin; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Sung Eun Kim; Kyung-Sang Yu
Pharmacokinetic comparison of a new sustained-release formulation of glimepiride/metformin 1/500 mg combination tablet and a sustained-release formulation of glimepiride/metformin 2/500 mg combination tablet in healthy Korean male volunteers: a randomized, 2-sequence, 2-period, 2-treatment crossover study.
Clinical therapeutics 2011;33(11):1809-18.
2011: H Jeon; T-E Kim; Sangku Lee; Sang-Goo Shin; S H Yoon; In-Jin Jang; Kyung-Sang Yu
Pharmacokinetics and tolerability of probucol after multiple oral administrations in healthy volunteers.
International journal of clinical pharmacology and therapeutics 2011;49(11):688-95.
2011: M K Park; K-H Shin; Sang-Goo Shin; S H Yoon; J-Y Cho; In-Jin Jang; wu gang; T-E Kim; Kyung-Sang Yu
Open label, three period, single sequence, study of 5, 25, 50 mg sertraline pharmacokinetics in healthy male Korean volunteers.
International journal of clinical pharmacology and therapeutics 2011;49(11):672-8.
2011: SeungHwan Lee; Wan Beom Park; Kwang-Hee Shin; Sang-Goo Shin; Seo Hyun Yoon; Dong Ho Ahn; Joo-Youn Cho; In-Jin Jang; Kyung-Sang Yu
Immunogenicity and safety of a single intramuscular dose of a diphtheria-tetanus toxoid (Td) vaccine (GC1107) in Korean adults.
Vaccine 2011;29(44):7638-43.
2011: Euitae Kim; Su Jin Kim; Yong Gil Kim; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jae Sung Lee; Jung Shin Park; Sang-Goo Shin; Federico E Turkheimer; Kyung-Sang Yu; Jun Soo Kwon
The use of healthy volunteers instead of patients to inform drug dosing studies: a [¹¹C]raclopride PET study.
Psychopharmacology 2011;217(4):515-23.
2011: You-Me Tae; Jae Gun Kwak; In-Jin Jang; Bo-Hyung Kim; Woong-Han Kim
Population pharmacokinetic analysis and dosing regimen optimization of aprotinin in neonates and young infants undergoing cardiopulmonary bypass.
Journal of clinical pharmacology 2011;51(8):1163-76.
2011: Sojeong Yi; Seo Hyun Yoon; Joo-Youn Cho; Yong-Ju Chung; In-Jin Jang; Tae Eun Kim; Hyun-Suk Shin; Sang-Goo Shin; Kyung-Sang Yu
Pharmacokinetics of extended-release versus conventional tramadol/acetaminophen fixed-dose combination tablets: an open-label, 2-treatment, multiple-dose, randomized-sequence crossover study in healthy korean male volunteers.
Clinical therapeutics 2011;33(6):728-37.
2011: Kiwon Kim; Young-Hwan Hwang; Han Ro; Yun Kyu Oh; Min-Gul Kim; Kyung-Sang Yu; Kwang-Hee Shin; In-Jin Jang; Sang Goo Shin; Curie Ahn; Kook-Hwan Oh
Pharmacokinetic profiles of ceftazidime after intravenous administration in patients undergoing automated peritoneal dialysis.
Antimicrobial agents and chemotherapy 2011;55(6):2523-7.
2011: SoJeong Yi; Tae-Eun Kim; Seo Hyun Yoon; Joo-Youn Cho; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Pharmacokinetic interaction of fimasartan, a new angiotensin II receptor antagonist, with amlodipine in healthy volunteers.
Journal of cardiovascular pharmacology 2011;57(6):682-9.
2011: Jae Yong Chung; Joo-Youn Cho; Hyeong-Seok Lim; Jung-Ryul Kim; Kyung-Sang Yu; Kyoung Soo Lim; Sang-Goo Shin; In-Jin Jang
Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(1):92-7.
2010: Seunghwan Lee; Seo Hyun Yoon; Joo-Youn Cho; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Relative bioavailability and tolerability of two formulations of bicalutamide 50-mg tablets: a randomized-sequence, open-label, two-period crossover study in healthy Korean male subjects.
Clinical therapeutics 2010;32(14):2496-501.
2010: Tae Eun Kim; Kyu-Pyo Kim; Bo-Hyung Kim; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Pharmacokinetic and pharmacodynamic comparison of two recombinant human erythropoietin formulations after single subcutaneous administration: an open-label, sequence-randomized, two-treatment crossover study in healthy Korean male volunteers.
Clinical therapeutics 2010;32(11):1968-76.
2010: Namyi Gu; Bo-Hyung Kim; HyouYoung Rhim; Jae-Yong Chung; Jung-Ryul Kim; Hyun-Suk Shin; Seo-Hyun Yoon; Joo-Youn Cho; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Comparison of the bioavailability and tolerability of fixed-dose combination glimepiride/metformin 2/500-mg tablets versus separate tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy Korean volunteers.
Clinical therapeutics 2010;32(7):1408-18.
2010: Kyoung-Soo Lim; In-Jin Jang; Bo-Hyung Kim; JaeWoo Kim; Ji-Young Jeon; You-Me Tae; Sojeong Yi; SoYoung Eum; Joo-Youn Cho; Sang-Goo Shin; Kyung-Sang Yu
Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects.
Clinical therapeutics 2010;32(4):659-66.
2010: Kwang-Hee Shin; Yong-ju Chung; Bo-Hyung Kim; Tae-Eun Kim; Hwa-Sook Kim; Joo-Youn Cho; In-Jin Jang; Sang-Goo Shin; Kyung-Sang Yu
Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects.
British journal of clinical pharmacology 2010;69(3):307-10.
2010: Kyunggon Kim; Sang Jin Kim; Hyeong Gon Yu; Jiyoung Yu; Kyong Soo Park; In-Jin Jang; Youngsoo Kim
Verification of biomarkers for diabetic retinopathy by multiple reaction monitoring.
Journal of proteome research 2010;9(2):689-99.
2010: Bo-Hyung Kim; Kyu-Pyo Kim; Kyoung Soo Lim; Jung-Ryul Kim; Seo Hyun Yoon; Joo-Youn Cho; Yong-Oh Lee; Kyung-Hee Lee; In-Jin Jang; Sang-Goo Shin; Kyung-Sang Yu
Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers.
Clinical therapeutics 2010;32(2):380-90.
2010: Bo-Hyung Kim; Jung-Ryul Kim; Min-Gul Kim; Kyu-Pyo Kim; Bong-Yong Lee; In-Jin Jang; Sang-Goo Shin; Kyung-Sang Yu
Pharmacodynamic (hemodynamic) and pharmacokinetic comparisons of S-amlodipine gentisate and racemate amlodipine besylate in healthy Korean male volunteers: two double-blind, randomized, two-period, two-treatment, two-sequence, double-dummy, single-dose crossover studies.
Clinical therapeutics 2010;32(1):193-205.
2009: Kwang-Hee Shin; Bo-Hyung Kim; Tae-Eun Kim; Jae Woo Kim; Sojeong Yi; Seo-Hyun Yoon; Joo-Youn Cho; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study.
Clinical therapeutics 2009;31(12):3009-20.
2009: Sarpong Mr.Samuel; Yong-Ju Chung; Bo-Hyung Kim; JH Shim; Seo-Hyun Yoon; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: an open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers.
Clinical therapeutics 2009;31(12):3000-8.
2009: Kyoung Soo Lim; Joo-Youn Cho; Bo-Hyung Kim; Jung-Ryul Kim; Hwa-Sook Kim; Dong-Kyu Kim; Sung-Ho Kim; Hyeon Joo Yim; Sung-Hack Lee; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers.
British journal of clinical pharmacology 2009;68(6):883-90.
2009: Jung Mook Kang; Nayoung Kim; Bongcheol Kim; JH Kim; Bong-Yong Lee; Ji Hyun Park; Mi Kyoung Lee; Hye Seung Lee; In-Jin Jang; Joo Sung Kim; Hyun Chae Jung; In Sung Song
Gastroprotective action of Cochinchina momordica seed extract is mediated by activation of CGRP and inhibition of cPLA(2)/5-LOX pathway.
Digestive diseases and sciences 2009;54(12):2549-60.
2009: Bo-Hyung Kim; Kwang-Hee Shin; Jaewoo Kim; Kyoung-Soo Lim; Kyu-Pyo Kim; Jung-Ryul Kim; Joo-Youn Cho; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Pharmacokinetic comparison of a new glimepiride 1-mg + metformin 500-mg combination tablet formulation and a glimepiride 2-mg + metformin 500-mg combination tablet formulation: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy, fasting Korean male volunteers.
Clinical therapeutics 2009;31(11):2755-64.
2009: Tae-Eun Kim; Bo-Hyung Kim; JaeWoo Kim; Kyu-Pyo Kim; SoJeong Yi; Hyun-Suk Shin; Yong-Oh Lee; Kyung-Hee Lee; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Comparison of the pharmacokinetics of ticlopidine between administration of a combined fixed-dose tablet formulation of ticlopidine 250 mg/ginkgo extract 80 mg, and concomitant administration of ticlopidine 250-mg and ginkgo extract 80-mg tablets: an open-label, two-treatment, single-dose, randomized-sequence crossover study in healthy Korean male volunteers.
Clinical therapeutics 2009;31(10):2249-57.
2009: Kyu-Pyo Kim; Bo-Hyung Kim; Kyoung-Soo Lim; Tae-Eun Kim; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Potential interactions between cilostazol and probucol: a two-part, single-dose, open-label study in healthy Korean male volunteers.
Clinical therapeutics 2009;31(10):2098-106.
2009: Kee Don Choi; Nayoung Kim; In-Jin Jang; Young Soo Park; Joo Youn Cho; Jung-Ryul Kim; Jai Shin; Hyun Chae Jung; In Sung Song
Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea.
Journal of gastroenterology and hepatology 2009;24(10):1617-24.
2009: Seung-Zhoo Yoon; In-Jin Jang; Yoon Ji Choi; Mae Hwa Kang; Hye Ja Lim; Young-Jin Lim; Hye Won Lee; Seong Ho Chang; Suk-Min Yoon
Association between tumor necrosis factor alpha 308G/A polymorphism and increased proinflammatory cytokine release after cardiac surgery with cardiopulmonary bypass in the Korean population.
Journal of cardiothoracic and vascular anesthesia 2009;23(5):646-50.
2009: SoJeong Yi; Joo-Youn Cho; Jang-hee Hong; In-Jin Jang; Bo-Hyung Kim; Jaewoo Kim; Kyu-Pyo Kim; Kyoung Soo Lim; Sang-Goo Shin; Kyung-Sang Yu
Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers.
Basic & clinical pharmacology & toxicology 2009;105(4):249-56.
2009: Kook-Hwan Oh; Chiweon Kim; Hankyu Lee; Hajeong Lee; Ji Yong Jung; Nam Joong Kim; Kyung-Sang Yu; Kwang-Hee Shin; In-Jin Jang; Curie Ahn
Pharmacokinetics of intravenous piperacillin administration in patients undergoing on-line hemodiafiltration.
Antimicrobial agents and chemotherapy 2009;53(8):3266-8.
2009: Won Kim; Jung-Hwan Yoon; Jung-Ryul Kim; In-Jin Jang; Yung-Jue Bang; Yoon Jun Kim; Hyo-Suk Lee
Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma.
Cancer chemotherapy and pharmacology 2009;64(3):497-507.
2009: Tae-Eun Kim; Bo-Hyung Kim; Jung-Ryul Kim; Kyoung Soo Lim; Jang Hee Hong; Kyu-Pyo Kim; Hwa-Sook Kim; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Effect of food on the pharmacokinetics of the oral phosphodiesterase 5 inhibitor udenafil for the treatment of erectile dysfunction.
British journal of clinical pharmacology 2009;68(1):43-6.
2009: Bo-Hyung Kim; SoJeong Yi; JaeWoo Kim; Kyoung-Soo Lim; Kyu-Pyo Kim; Bongyong Lee; Sang-Goo Shin; In-Jin Jang; Kyung-Sang Yu
Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea.
Clinical therapeutics 2009;31(6):1234-43.
2009: Hyeong-Seok Lim; Jeong-Soo Im; Joo-Youn Cho; Kyun-Seop Bae; Terry A Klein; Joon Sup Yeom; Tae-Seon Kim; Jae-Seon Choi; In-Jin Jang; Jae-Won Park
Pharmacokinetics of hydroxychloroquine and its clinical implications in chemoprophylaxis against malaria caused by Plasmodium vivax.
Antimicrobial agents and chemotherapy 2009;53(4):1468-75.
2009: Bo-Hyung Kim; Jung-Ryul Kim; Kyoung-Soo Lim; Jae Woo Kim; Kyu-Pyo Kim; Jang-Hee Hong; In-Jin Jang; Sang-Goo Shin; Kyung-Sang Yu; Takanori Tanaka
An open-label, single-dose, parallel-group, dose-increasing study comparing the pharmacokinetics and tolerability of pilsicainide hydrochloride in healthy Korean and Japanese male subjects.
Clinical therapeutics 2009;31(3):609-18.
2009: Dong Wook Kim; Sang Kun Lee; Kon Chu; In-Jin Jang; Kyung-Sang Yu; Joo-Youn Cho; Seon Jeong Kim
Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy.
Epilepsy research 2009;84(1):86-90.
2008: Jung-Ryul Kim; Hyo-Bum Seo; Joo-Youn Cho; Do-Hyung Kang; Yong Ku Kim; Won-Myong Bahk; Kyung-Sang Yu; Sang-Goo Shin; Jun Soo Kwon; In-Jin Jang
Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients.
British journal of clinical pharmacology 2008;66(6):802-10.
2008: Jun Soo Kwon; Euitae Kim; Do-Hyung Kang; Jung Seok Choi; Kyung-Sang Yu; In-Jin Jang; Sang-Goo Shin
Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(12):897-907.
2008: Kyoung Soo Lim; Joo-Youn Cho; In-Jin Jang; Bo-Hyung Kim; JaeWoo Kim; Ji-Young Jeon; Yu-Mi Tae; SoJeong Yi; SoYoung Eum; Sang-Goo Shin; Kyung-Sang Yu
Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.
British journal of clinical pharmacology 2008;66(5):660-6.
2008: Kyoung Soo Lim; Jung-Ryul Kim; Yun-Jung Choi; Kwang-Hee Shin; Kyu-Pyo Kim; Jang-Hee Hong; Joo-Youn Cho; Hyun-Suk Shin; Kyung-Sang Yu; Sang-Goo Shin; O Hwan Kwon; Dal-Mi Hwang; Jeong-Ae Kim; In-Jin Jang
Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: a dose-block-randomized, double-blind, placebo-controlled, ascending single-dose, Phase I study.
Clinical therapeutics 2008;30(10):1817-30.
2008: Bo-Hyung Kim; Hyeong-Seok Lim; Jae-Yong Chung; Jung-Ryul Kim; Kyoung Soo Lim; Dong-Ryul Sohn; Joo-Youn Cho; Kyung-Sang Yu; Sang-Goo Shin; Jae-Seung Paick; In-Jin Jang
Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.
British journal of clinical pharmacology 2008;65(6):848-54.
2008: Jae-Yong Chung; Joo-Youn Cho; Kyung-Sang Yu; Jung-Ryul Kim; Kyoung-Soo Lim; D-R Sohn; Sang-Goo Shin; In-Jin Jang
Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects.
Clinical pharmacology and therapeutics 2008;83(4):595-600.
2008: Euitae Kim; Jun Soo Kwon; Yong-Wook Shin; Jae Sung Lee; Won Jun Kang; Hang Joon Jo; Jong-Min Lee; Kyung-Sang Yu; Do-Hyung Kang; Joo-Youn Cho; In-Jin Jang; Sang-Goo Shin
Taq1A polymorphism in the dopamine D2 receptor gene predicts brain metabolic response to aripiprazole in healthy male volunteers.
Pharmacogenetics and genomics 2008;18(2):91-7.
2007: Hyeong-Seok Lim; Han Ju Lee; Keun Seok Lee; Eun Sook Lee; In-Jin Jang; Jae Y Ro
Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(25):3837-45.
2007: Ji Ha Choi; Byung Min Ahn; Jihyun Yi; Ji Hyun Lee; Jeong Ho Lee; Suk Woo Nam; Chae Yoon Chon; Kwang-Hyub Han; Sang Hoon Ahn; In-Jin Jang; Joo-Youn Cho; Yousin Suh; Mi-Ook Cho; Jong-Eun Lee; Kyung Hwan Kim; Min Goo Lee
MRP2 haplotypes confer differential susceptibility to toxic liver injury.
Pharmacogenetics and genomics 2007;17(6):403-15.
2007: Kyoung-Soo Lim; J S Kwon; In-Jin Jang; J M Jeong; J S Lee; H W Kim; Won Jun Kang; Jung-Ryul Kim; Joo-Youn Cho; E Kim; S Y Yoo; Sang-Goo Shin; Kyung-Sang Yu
Modeling of brain D2 receptor occupancy-plasma concentration relationships with a novel antipsychotic, YKP1358, using serial PET scans in healthy volunteers.
Clinical pharmacology and therapeutics 2007;81(2):252-8.
2007: Michaela Vossen; Michael Sevestre; Christoph Niederalt; In-Jin Jang; Stefan Willmann; Andrea N Edginton
Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models.
Theoretical biology & medical modelling 2007;4():13.
2007: Hyeong-Seok Lim; Joo-Youn Cho; Dal-Seok Oh; Jae-Yong Chung; Kyoung-Sup Hong; Kyun-Seop Bae; Kyung-Sang Yu; Kyung-Hoon Lee; In-Jin Jang; Sang-Goo Shin
Angiotensin II type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II.
European journal of clinical pharmacology 2007;63(1):17-26.
2006: Min-Ho Choi; Byung-Chan Chang; Seung-Jin Lee; In-Jin Jang; Sang-Goo Shin; Weon-Gyu Kho; Jin-Ho Chun; Sung-Tae Hong
Therapeutic evaluation of sustained-releasing praziquantel (SRP) for clonorchiasis: phase 1 and 2 clinical studies.
The Korean journal of parasitology 2006;44(4):361-6.
2006: Euitae Kim; Kyung-Sang Yu; Joo-Youn Cho; Yong-Wook Shin; So Young Yoo; Young Youn Kim; In-Jin Jang; Sang-Goo Shin; Jun Soo Kwon
Effects of DRD2 and CYP2D6 genotypes on delta EEG power response to aripiprazole in healthy male volunteers: a preliminary study.
Human psychopharmacology 2006;21(8):519-28.
2006: Ji-Yeob Choi; Kyoung-Mu Lee; Dong-Young Noh; Sei-Hyun Ahn; Jong-Eun Lee; Wonshik Han; In-Jin Jang; Sang-Goo Shin; Keun-Young Yoo; Richard B Hayes; Daehee Kang
Genetic polymorphisms of eNOS, hormone receptor status, and survival of breast cancer.
Breast cancer research and treatment 2006;100(2):213-8.
2006: Eun-Jin Yeo; Ji-Hye Ryu; Yang-Sook Chun; Young-Suk Cho; In-Jin Jang; HoSung Cho; Jinho Kim; Myung-Suk Kim; Jong-Wan Park
YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases.
Cancer research 2006;66(12):6345-52.
2006: Jung-Won Suh; Bon-Kwon Koo; Shu-Ying Zhang; Kyung-Woo Park; Joo-Youn Cho; In-Jin Jang; Dong-Soon Lee; Dae-Won Sohn; Myoung-Mook Lee; Hyo-Soo Kim
Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2006;174(12):1715-22.
2006: Ji-Youn Han; Hyeong-Seok Lim; Eun-Soon Shin; Yeon-Kyeong Yoo; Yong Hoon Park; Jong-Eun Lee; In-Jin Jang; Dae Ho Lee; Jin Soo Lee
Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(15):2237-44.
2005: Jae-Yong Chung; Joo-Youn Cho; Kyung-Sang Yu; Jung-Ryul Kim; Dal-Seok Oh; Hye-Ryung Jung; Kyoung-Soo Lim; Ki-Ho Moon; Sang-Goo Shin; In-Jin Jang
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers.
Clinical pharmacology and therapeutics 2005;78(4):342-50.
2005: Jae-Yong Chung; Joo-Youn Cho; Kyung-Sang Yu; Jung-Ryul Kim; Hye-Ryung Jung; Kyoung-Soo Lim; In-Jin Jang; Sang-Goo Shin
Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers.
Clinical pharmacology and therapeutics 2005;77(6):486-94.
2005: Ji-Yeob Choi; Kyoung-Mu Lee; Sue Kyung Park; Dong-Young Noh; Sei-Hyun Ahn; Hye-Won Chung; Wonshik Han; Jeong Soo Kim; Sang-Goo Shin; In-Jin Jang; Keun-Young Yoo; Ari Hirvonen; Daehee Kang
Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1090-5.
2004: Joo-Youn Cho; Hyeong-Seok Lim; Jae-Yong Chung; Kyung-Sang Yu; Jung-Ryul Kim; Sang-Goo Shin; In-Jin Jang
Haplotype structure and allele frequencies of CYP2B6 in a Korean population.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(12):1341-4.
2004: So-Young Yi; Kyoung-Sup Hong; Hyeong-Seok Lim; Jae-Yong Chung; Dal-Seok Oh; Jung-Ryul Kim; Hye-Ryung Jung; Joo-Youn Cho; Kyung-Sang Yu; In-Jin Jang; Sang-Goo Shin
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
Clinical pharmacology and therapeutics 2004;76(5):418-27.
2004: Kyung-Sang Yu; Joo-Youn Cho; In-Jin Jang; Kyoung-Sup Hong; Jae-Yong Chung; Jung-Ryul Kim; Hyeong-Seok Lim; Dal-Seok Oh; So-Young Yi; Kwang-Hyeon Liu; Jae-Gook Shin; Sang-Goo Shin
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.
Clinical pharmacology and therapeutics 2004;76(2):104-12.
2004: Kyung-Sang Yu; Kyun-Seop Bae; Ji-Hong Shon; Joo-Youn Cho; So-Young Yi; Jae-Yong Chung; Hyeong-Seok Lim; In-Jin Jang; Sang-Goo Shin; Keun-Seog Song; Byoung-Seok Moon
Pharmacokinetic and pharmacodynamic evaluation of a novel proton pump inhibitor, YH1885, in healthy volunteers.
Journal of clinical pharmacology 2004;44(1):73-82.
2003: Joo Youn Cho; Hyeong Seok Lim; Kyung-Sang Yu; Hyun Joo Shim; In-Jin Jang; Sang-Goo Shin
Sensitive liquid chromatography assay with ultraviolet detection for a new phosphodiesterase V inhibitor, DA-8159, in human plasma and urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;795(2):179-86.
2003: Ji Hyun Lee; Ji Ha Choi; Wan Namkung; John W Hanrahan; Joon Chang; Si Young Song; Seung Woo Park; Dong Soo Kim; Joo-Heon Yoon; Yousin Suh; In-Jin Jang; Joo Hyun Nam; Sung Joon Kim; Mi-Ook Cho; Jong-Eun Lee; Kyung Hwan Kim; Min Goo Lee
A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases.
Human molecular genetics 2003;12(18):2321-32.
2003: Curie Ahn; Kook-Hwan Oh; Kiwon Kim; Kyung Yi Lee; Jung Geon Lee; Myung Don Oh; Yonsu Kim; Jin Suk Han; Suhnggwon Kim; Jung Sang Lee; In-Jin Jang; Sang-Goo Shin
Effect of peritoneal dialysis on plasma and peritoneal fluid concentrations of isoniazid, pyrazinamide, and rifampin.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2003;23(4):362-7.
2003: Myo-Kyoung Kim; Joo-Youn Cho; Hyeong-Seok Lim; Kyoung-Sup Hong; Jae-Yong Chung; Kyun-Seop Bae; Dal-Seok Oh; Sang-Goo Shin; Sang-Hun Lee; Dong-Ho Lee; Bumchan Min; In-Jin Jang
Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects.
European journal of clinical pharmacology 2003;59(2):111-6.
2003: Joo Youn Cho; Hyo Bum Seo; Kyung-Sang Yu; Kyun-Seop Bae; So Young Yi; In-Jin Jang; Sang-Goo Shin
Simple and sensitive determination of the new antitumor drug CKD-602 in human plasma by liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;784(1):25-31.
2002: Jae-Hyon Bahk; Joohon Sung; In-Jin Jang
A comparison of ketamine and lidocaine spray with propofol for the insertion of laryngeal mask airway in children: a double-blinded randomized trial.
Anesthesia and analgesia 2002;95(6):1586-9, table of contents.
2002: Joo-Youn Cho; Kyung-Sang Yu; In-Jin Jang; Byung-Hwan Yang; Sang-Goo Shin; Dong-Seok Yim
Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19.
British journal of clinical pharmacology 2002;53(4):393-7.
2001: Kyung-Sang Yu; Joo-Youn Cho; Ji-Hong Shon; K S Bae; So-Young Yi; Hyeong-Seok Lim; In-Jin Jang; Sang-Goo Shin
Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin.
Clinical pharmacology and therapeutics 2001;70(3):228-36.
2001: Ki Young Na; Jin Suk Han; Yon Su Kim; Curie Ahn; Suhnggwon Kim; Jung Sang Lee; K S Bae; In-Jin Jang; Sang-Goo Shin; W Huh; Un Sil Jeon
Does albumin preinfusion potentiate diuretic action of furosemide in patients with nephrotic syndrome?
Journal of Korean medical science 2001;16(4):448-54.
2001: Dong-Seok Yim; S K Parkb; Keun-Young Yoo; Kyung-Sik Yoon; H H Chung; H L Kang; Se-Hyun Ahn; Dong-Young Noh; Kuk Jin Choe; In-Jin Jang; Sang-Goo Shin; Paul T Strickland; Ari Hirvonen; Daehee Kang
Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer.
Pharmacogenetics 2001;11(4):279-86.
2001: Kyung-Sang Yu; Dong-Seok Yim; Joo-Youn Cho; S S Park; J Y Park; K H Lee; In-Jin Jang; So-Young Yi; K S Bae; Sang-Goo Shin
Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.
Clinical pharmacology and therapeutics 2001;69(4):266-73.
2000: In-Jin Jang; Kyung-Sang Yu; Ji-Hong Shon; Kyun-Seop Bae; Joo-Youn Cho; So-Young Yi; Sang-Goo Shin; K H Ryu; Y B Cho; D K Kim; Sung-Eun Yoo
Pharmacokinetic/pharmacodynamic evaluation of a novel potassium channel opener, SKP-450, in healthy volunteers.
Journal of clinical pharmacology 2000;40(7):752-61.
2000: Young-Ran Yoon; In-June Cha; Ji-Hong Shon; Kyoung-Ah Kim; Y N Cha; In-Jin Jang; C W Park; Sang-Goo Shin; David A Flockhart; Jae-Gook Shin
Relationship of paroxetine disposition to metoprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects.
Clinical pharmacology and therapeutics 2000;67(5):567-76.
1999: Dong Young Lee; K U Lee; Jun Soo Kwon; In-Jin Jang; M J Cho; Sang-Goo Shin; J I Woo
Pharmacokinetic-pharmacodynamic modeling of risperidone effects on electroencephalography in healthy volunteers.
Psychopharmacology 1999;144(3):272-8.
1999: JW Ko; In-Jin Jang; Jae-Gook Shin; S K Nam; Sang-Goo Shin; David A Flockhart
Theophylline pharmacokinetics are not altered by lansoprazole in CYP2C19 poor metabolizers.
Clinical pharmacology and therapeutics 1999;65(6):606-14.
1999: In-Jin Jang; I S Kim; WJ Park; K S Yoo; Dong-Seok Yim; H K Kim; Sang-Goo Shin; W H Chang; Na Gyong Lee; SB Jung; D H Ahn; Yang Je Cho; Bo Young Ahn; Y Lee; YG Kim; nam soon woo; HS Kim
Human immune response to a Pseudomonas aeruginosa outer membrane protein vaccine.
Vaccine 1999;17(2):158-68.
1997: Jin Suk Han; Yon Su Kim; Ho Jun Chin; Un Sil Jeon; Curie Ahn; Suhnggwon Kim; Jung Sang Lee; In-Jin Jang; Sang-Goo Shin
Temporal changes and reversibility of carbamylated hemoglobin in renal failure.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;30(1):36-40.
1996: In-Jin Jang; Sang-Goo Shin; K H Lee; D S Yim; M S Lee; H H Koo; H K Kim; D R Sohn
Erythrocyte thiopurine methyltransferase activity in a Korean population.
British journal of clinical pharmacology 1996;42(5):638-41.
1994: S W Lee; In-Jin Jang; Sang-Goo Shin; K H Lee; D S Yim; S W Kim; S J Oh; S H Lee
CYP1A2 activity as a risk factor for bladder cancer.
Journal of Korean medical science 1994;9(6):482-9.
1993: Y G Kim; Jae-Gook Shin; Sang-Goo Shin; In-Jin Jang; Suhnggwon Kim; Jung Sang Lee; Jin Suk Han; Y N Cha
Decreased acetylation of isoniazid in chronic renal failure.
Clinical pharmacology and therapeutics 1993;54(6):612-20.
1993: J H Rha; In-Jin Jang; K H Lee; W S Chong; Sang-Goo Shin; N Lee; H J Myung
Pharmacokinetic comparison of two valproic acid formulations--a plain and a controlled release enteric-coated tablets.
Journal of Korean medical science 1993;8(4):251-6.
1992: D R Sohn; M Kusaka; T Ishizaki; Sang-Goo Shin; In-Jin Jang; Jae-Gook Shin; K Chiba
Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.
Clinical pharmacology and therapeutics 1992;52(2):160-9.
1992: D R Sohn; M Kusaka; Sang-Goo Shin; In-Jin Jang; K Chiba; T Ishizaki
Utility of a one-point (3-hour postdose) plasma metabolic ratio as a phenotyping test using metoprolol in two east Asian populations.
Therapeutic drug monitoring 1992;14(3):184-9.
1990: Sang-Goo Shin; J K Roh; N S Lee; Jae-Gook Shin; In-Jin Jang; C W Park; H J Myung
Kinetics of isoniazid transfer into cerebrospinal fluid in patients with tuberculous meningitis.
Journal of Korean medical science 1990;5(1):39-45.