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Paul Ayton

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Anatomy

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Publications

TOP 3
Paul M Ayton; Everett H Chen; Michael L Cleary
Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.
Antonio Cozzio; Emmanuelle Passegué; Paul M Ayton; Holger Karsunky; Michael L Cleary; Irving L Weissman
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.
Paul M Ayton; Michael L Cleary
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.

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All Publications

2004: Paul M Ayton; Everett H Chen; Michael L Cleary
Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.
Molecular and cellular biology 2004;24(23):10470-8.
2003: Antonio Cozzio; Emmanuelle Passegué; Paul M Ayton; Holger Karsunky; Michael L Cleary; Irving L Weissman
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.
Genes & development 2003;17(24):3029-35.
2003: Paul M Ayton; Michael L Cleary
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.
Genes & development 2003;17(18):2298-307.
2003: Chi Wai So; Min Lin; Paul M Ayton; Everett H Chen; Michael L Cleary
Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias.
Cancer cell 2003;4(2):99-110.
2003: Kenji Deguchi; Paul M Ayton; Melina Carapeti; Jeffery L Kutok; Cynthia S Snyder; Ifor Williams; Nicholas C P Cross; Christopher K Glass; Michael L Cleary; D Gary Gilliland
MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.
Cancer cell 2003;3(3):259-71.
2002: Akihiko Yokoyama; Issay Kitabayashi; Paul M Ayton; Michael L Cleary; Misao Ohki
Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties.
Blood 2002;100(10):3710-8.
2002: Jorge F DiMartino; Paul M Ayton; Everett H Chen; Clarissa C Naftzger; Bryan D Young; Michael L Cleary
The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.
Blood 2002;99(10):3780-5.
2001: Paul M Ayton; Michael L Cleary
Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins.
Oncogene 2001;20(40):5695-707.
2000: Jorge F DiMartino; T Miller; Paul M Ayton; T Landewe; Jay L Hess; Michael L Cleary; Ali Shilatifard
A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL.
Blood 2000;96(12):3887-93.

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