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Lennert Janssen

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Physiology

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TOP 3
Tineke van den Hoorn; Petra Paul; Hans Janssen; Lennert Janssen; Jacques Neefjes
Dynamics within tetraspanin pairs affect MHC class II expression.
Petra Paul; Tineke van den Hoorn; Marlieke L M Jongsma; Mark J Bakker; Rutger Hengeveld; Lennert Janssen; Peter Cresswell; David A Egan; Marieke van Ham; Anja Ten Brinke; Huib Ovaa; Roderick L Beijersbergen; Coenraad Kuijl; Jacques Neefjes
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.
Wilbert Zwart; Victor Peperzak; Evert de Vries; Anna M Keller; Gerda van der Horst; Elise A M Veraar; Ulf Geumann; Hans Janssen; Lennert Janssen; Shalin Naik; Jacques Neefjes; Jannie Borst
The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.

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All Publications

2012: Tineke van den Hoorn; Petra Paul; Hans Janssen; Lennert Janssen; Jacques Neefjes
Dynamics within tetraspanin pairs affect MHC class II expression.
Journal of cell science 2012;125(Pt 2):328-39.
2011: Petra Paul; Tineke van den Hoorn; Marlieke L M Jongsma; Mark J Bakker; Rutger Hengeveld; Lennert Janssen; Peter Cresswell; David A Egan; Marieke van Ham; Anja Ten Brinke; Huib Ovaa; Roderick L Beijersbergen; Coenraad Kuijl; Jacques Neefjes
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.
Cell 2011;145(2):268-83.
2010: Wilbert Zwart; Victor Peperzak; Evert de Vries; Anna M Keller; Gerda van der Horst; Elise A M Veraar; Ulf Geumann; Hans Janssen; Lennert Janssen; Shalin Naik; Jacques Neefjes; Jannie Borst
The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.
Journal of cell science 2010;123(Pt 21):3817-27.
2009: Baoxu Pang; Joost Neijssen; Xiaohang Qiao; Lennert Janssen; Hans Janssen; Christoph Lippuner; Jacques Neefjes
Direct antigen presentation and gap junction mediated cross-presentation during apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1083-90.
2009: Nuno Rocha; Coenraad Kuijl; Rik van der Kant; Lennert Janssen; Diane Houben; Hans Janssen; Wilbert Zwart; Jacques Neefjes
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.
The Journal of cell biology 2009;185(7):1209-25.
2007: Coenraad Kuijl; Nigel D L Savage; Marije Marsman; Adriaan W Tuin; Lennert Janssen; David A Egan; Mirjam Ketema; Rian van den Nieuwendijk; Susan J F van den Eeden; Annemieke Geluk; Alex Poot; Gijsbert A van der Marel; Roderick L Beijersbergen; Herman S Overkleeft; Tom H M Ottenhoff; Jacques Neefjes
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.
Nature 2007;450(7170):725-30.
2007: Marie Johansson; Nuno Rocha; Wilbert Zwart; Ingrid Jordens; Lennert Janssen; Coenraad Kuijl; Vesa M Olkkonen; Jacques Neefjes
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin.
The Journal of cell biology 2007;176(4):459-71.
2006: Jean Paul ten Klooster; Eva E Evers; Lennert Janssen; Laura M Machesky; Frits Michiels; Peter L Hordijk; John G Collard
Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
The Biochemical journal 2006;397(1):39-45.
2006: Marije Marsman; Ingrid Jordens; Nuno Rocha; Coenraad Kuijl; Lennert Janssen; Jacques Neefjes
A splice variant of RILP induces lysosomal clustering independent of dynein recruitment.
Biochemical and biophysical research communications 2006;344(3):747-56.
2006: Carla A Herberts; Joost Neijssen; Jolanda de Haan; Lennert Janssen; Jan Wouter Drijfhout; Eric Reits; Jacques Neefjes
Cutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2697-701.
2005: Mar Fernandez-Borja; Lennert Janssen; Desiree Verwoerd; Peter L Hordijk; Jacques Neefjes
RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1.
Journal of cell science 2005;118(Pt 12):2661-70.
2005: Joost Neijssen; Carla A Herberts; Jan Wouter Drijfhout; Eric Reits; Lennert Janssen; Jacques Neefjes
Cross-presentation by intercellular peptide transfer through gap junctions.
Nature 2005;434(7029):83-8.
2005: Wilbert Zwart; Alexander Griekspoor; Coenraad Kuijl; Marije Marsman; Jacco van Rheenen; Hans Janssen; Jero Calafat; Marieke van Ham; Lennert Janssen; Marcel van Lith; Kees Jalink; Jacques Neefjes
Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.
Immunity 2005;22(2):221-33.
2004: Rob Michalides; Alexander Griekspoor; Astrid Balkenende; Desiree Verwoerd; Lennert Janssen; Kees Jalink; Arno N Floore; Arno Velds; Laura J van't Veer; Jacques Neefjes
Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer.
Cancer cell 2004;5(6):597-605.
2004: Marije Marsman; Ingrid Jordens; Coenraad Kuijl; Lennert Janssen; Jacques Neefjes
Dynein-mediated vesicle transport controls intracellular Salmonella replication.
Molecular biology of the cell 2004;15(6):2954-64.
2004: Eric Reits; Joost Neijssen; Carla A Herberts; Willemien Benckhuijsen; Lennert Janssen; Jan Wouter Drijfhout; Jacques Neefjes
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.
Immunity 2004;20(4):495-506.
2001: Ingrid Jordens; Mar Fernandez-Borja; Marije Marsman; S Dusseljee; Lennert Janssen; Jero Calafat; Hans Janssen; R Wubbolts; Jacques Neefjes
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors.
Current biology : CB 2001;11(21):1680-5.
2000: GC Zondag; Eva E Evers; Jean Paul ten Klooster; Lennert Janssen; Rob A van der Kammen; John G Collard
Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition.
The Journal of cell biology 2000;149(4):775-82.
2000: Frits Michiels; Rob A van der Kammen; Lennert Janssen; G Nolan; John G Collard
Expression of Rho GTPases using retroviral vectors.
Methods in enzymology 2000;325():295-302.