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Maria Janusz

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Proline-Rich Protein Domains

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Agnieszka Zabłocka; Maria Janusz
Effect of the proline-rich polypeptide complex/colostrinin™ on the enzymatic antioxidant system.
Maria Janusz; A Zabłocka
Colostral proline-rich polypeptides--immunoregulatory properties and prospects of therapeutic use in Alzheimer's disease.
Agnieszka Zabłocka; Jakub Siednienko; Małgorzata Mitkiewicz; Wojciech A Gorczyca; Józef Lisowski; Maria Janusz
Proline-rich polypeptide complex (PRP) regulates secretion of inflammatory mediators by its effect on NF-kappaB activity.

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All Publications

2012: Agnieszka Zabłocka; Maria Janusz
Effect of the proline-rich polypeptide complex/colostrinin™ on the enzymatic antioxidant system.
Archivum immunologiae et therapiae experimentalis 2012;60(5):383-90.
2010: Maria Janusz; A Zabłocka
Colostral proline-rich polypeptides--immunoregulatory properties and prospects of therapeutic use in Alzheimer's disease.
Current Alzheimer research 2010;7(4):323-33.
2010: Agnieszka Zabłocka; Jakub Siednienko; Małgorzata Mitkiewicz; Wojciech A Gorczyca; Józef Lisowski; Maria Janusz
Proline-rich polypeptide complex (PRP) regulates secretion of inflammatory mediators by its effect on NF-kappaB activity.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2010;64(1):16-20.
2009: Maria Janusz; Mirosław Woszczyna; Marek Lisowski; Adriana Kubis; Józefa Macała; Teodor Gotszalk; Józef Lisowski
Ovine colostrum nanopeptide affects amyloid beta aggregation.
FEBS letters 2009;583(1):190-6.
2008: Adriana M Kubis; Maria Janusz
[Alzheimer's disease: new prospects in therapy and applied experimental models].
Postȩpy higieny i medycyny doświadczalnej (Online) 2008;62():372-92.
2008: Agnieszka Zabłocka; Maria Janusz
[The two faces of reactive oxygen species].
Postȩpy higieny i medycyny doświadczalnej (Online) 2008;62():118-24.
2007: Agnieszka Zabłocka; Maria Janusz; Józefa Macała; Józef Lisowski
A proline-rich polypeptide complex (PRP) isolated from ovine colostrum. Modulation of H2O2 and cytokine induction in human leukocytes.
International immunopharmacology 2007;7(7):981-8.
2007: Agnieszka Zabłocka; Maria Janusz
[Structure and function of the central nervous system].
Postȩpy higieny i medycyny doświadczalnej (Online) 2007;61():454-60.
2005: Adriana Kubis; Ewa Marcinkowska; Maria Janusz; Józef Lisowski
Studies on the mechanism of action of a proline-rich polypeptide complex (PRP): effect on the stage of cell differentiation.
Peptides 2005;26(11):2188-92.
2005: Agnieszka Zabłocka; Maria Janusz; Józefa Macała; Józef Lisowski
A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice.
Regulatory peptides 2005;125(1-3):35-9.
2002: Jerzy Leszek; Anna D Inglot; Maria Janusz; Franciszek Byczkiewicz; Andrzej Kiejna; Jerzy A Georgiades; Józef Lisowski
Colostrinin proline-rich polypeptide complex from ovine colostrum--a long-term study of its efficacy in Alzheimer's disease.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(10):PI93-6.
2001: A Zabłocka; Maria Janusz; K Rybka; I Wirkus-Romanowska; G Kupryszewski; Józef Lisowski
Cytokine-inducing activity of a proline-rich polypeptide complex (PRP) from ovine colostrum and its active nonapeptide fragment analogs.
European cytokine network 2001;12(3):462-7.
2001: Piotr Popik; Z Galoch; Maria Janusz; Józef Lisowski; Jerzy Vetulani
Cognitive effects of Colostral-Val nonapeptide in aged rats.
Behavioural brain research 2001;118(2):201-8.
1999: B Domaraczenko; Maria Janusz; Beata Orzechowska; W Jarosz; Zofia Blach-Olszewska
Effect of proline rich polypeptide from ovine colostrum on virus replication in human placenta and amniotic membrane at term; possible role of endogenous tumour necrosis factor alpha.
Placenta 1999;20(8):695-701.
1999: Piotr Popik; Bartosz Bobula; Maria Janusz; Józef Lisowski; Jerzy Vetulani
Colostrinin, a polypeptide isolated from early milk, facilitates learning and memory in rats.
Pharmacology, biochemistry, and behavior 1999;64(1):183-9.
1999: Jerzy Leszek; Anna D Inglot; Maria Janusz; Józef Lisowski; K Krukowska; Jerzy A Georgiades
Colostrinin: a proline-rich polypeptide (PRP) complex isolated from ovine colostrum for treatment of Alzheimer's disease. A double-blind, placebo-controlled study.
Archivum immunologiae et therapiae experimentalis 1999;47(6):377-85.
1998: I Sokal; Maria Janusz; Józef Lisowski
Interaction of IgG immunoglobulins with the guinea pig peritoneal macrophage Fc gamma receptors. Effect on the association of the receptors with the membrane skeleton and the cytoskeleton.
The international journal of biochemistry & cell biology 1998;30(12):1353-65.
1998: Beata Orzechowska; Maria Janusz; B Domaraczenko; Z Błach-Olszewska
Antiviral effect of proline-rich polypeptide in murine resident peritoneal cells.
Acta virologica 1998;42(2):75-8.
1998: I Sokal; Maria Janusz; H Miecznikowska; G Kupryszewski; Józef Lisowski
Effect of colostrinin, an immunomodulatory proline-rich polypeptide from ovine colostrum, on sialidase and beta-galactosidase activities in murine thymocytes.
Archivum immunologiae et therapiae experimentalis 1998;46(3):193-8.
1997: E Piasecki; Anna D Inglot; M Winiarska; K Krukowska; Maria Janusz; Józef Lisowski
Coincidence between spontaneous release of interferon and tumor necrosis factor by colostral leukocytes and the production of a colostrinine by human mammary gland after normal delivery.
Archivum immunologiae et therapiae experimentalis 1997;45(1):109-17.
1997: Z Błach-Olszewska; Maria Janusz
Stimulatory effect of ovine colostrinine (a proline-rich polypeptide) on interferons and tumor necrosis factor production by murine resident peritoneal cells.
Archivum immunologiae et therapiae experimentalis 1997;45(1):43-7.
1996: Anna D Inglot; Maria Janusz; Józef Lisowski
Colostrinine: a proline-rich polypeptide from ovine colostrum is a modest cytokine inducer in human leukocytes.
Archivum immunologiae et therapiae experimentalis 1996;44(4):215-24.
1995: I Sokal; A Kułacz; W Gorczyca; Maria Janusz; Józef Lisowski
Guinea pig peritoneal macrophages. Differential effects of lectins on interaction with IgG immunoglobulins.
Cell biochemistry and function 1995;13(1):25-30.
1993: Maria Janusz; Józef Lisowski
Proline-rich polypeptide (PRP)--an immunomodulatory peptide from ovine colostrum.
Archivum immunologiae et therapiae experimentalis 1993;41(5-6):275-9.
1991: Zbigniew Szewczuk; A Kubik; G Gocka; Zbigniew Wieczorek; Michal Zimecki; Maria Janusz
New analogs of the immunoregulatory PRP-pentapeptide.
Peptides 1991;12(3):487-92.
1991: Michal Zimecki; T Hraba; Maria Janusz; Józef Lisowski; Zbigniew Wieczorek
Effect of a proline-rich polypeptide (PRP) on the development of hemolytic anemia and survival of New Zealand black (NZB) mice.
Archivum immunologiae et therapiae experimentalis 1991;39(5-6):461-7.
1990: W Gorczyca; Maria Janusz; Zbigniew Wieczorek; Józef Lisowski
Shedding of the guinea pig peritoneal macrophage Fc gamma receptor. Effect on apparent association constant and on the number of IgG-binding sites on the cells.
Archivum immunologiae et therapiae experimentalis 1990;38(5-6):335-45.
1989: Zbigniew Wieczorek; Michal Zimecki; K Spiegel; Józef Lisowski; Maria Janusz
Differentiation of T cells into helper cells from immature precursors: identification of a target cell for a proline-rich polypeptide (PRP).
Archivum immunologiae et therapiae experimentalis 1989;37(3-4):313-22.
1988: Zbigniew Szewczuk; A Kubik; Ignacy Z Siemion; Zbigniew Wieczorek; K Spiegel; Michal Zimecki; Maria Janusz; Józef Lisowski
Conformational modification of the PRP-hexapeptide by a direct covalent attachment of aromatic side chain groups.
International journal of peptide and protein research 1988;32(2):98-103.
1988: Michael Julius; Maria Janusz; Józef Lisowski
A colostral protein that induces the growth and differentiation of resting B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1366-71.
1988: J Boratyński; Maria Janusz; J Mikulska; M Niezgódka; Maciej Ugorski; Zbigniew Wieczorek; Józef Lisowski
Interaction of membrane-bound Fc gamma receptors with the cytoskeletal matrix.
Archivum immunologiae et therapiae experimentalis 1988;36(5):595-607.
1988: Józef Lisowski; Zbigniew Wieczorek; Maria Janusz; M Zimecki
Proline-rich polypeptide (PRP) from ovine colostrum. Bi-directional modulation of binding of peanut agglutinin, resistance to hydrocortisone, and helper activity in murine thymocytes.
Archivum immunologiae et therapiae experimentalis 1988;36(4):381-93.
1987: Maria Janusz; Zbigniew Wieczorek; K Spiegel; A Kubik; Zbigniew Szewczuk; Ignacy Z Siemion; Józef Lisowski
Immunoregulatory properties of synthetic peptides, fragments of a proline-rich polypeptide (PRP) from ovine colostrum.
Molecular immunology 1987;24(10):1029-31.
1987: Michal Zimecki; C W Pierce; Maria Janusz; Zbigniew Wieczorek; Józef Lisowski
Proliferative response of T lymphocytes to a proline-rich polypeptide (PRP): PRP mimics mitogenic activity of Il-1.
Archivum immunologiae et therapiae experimentalis 1987;35(3):339-49.
1986: Maria Janusz; M Niezgódka; Zbigniew Wieczorek; Józef Lisowski
A mild method for the purification of guinea pig peritoneal macrophage Fc gamma receptors. Affinity chromatography and elution of the receptor with reducing agents.
Journal of immunological methods 1986;86(1):119-24.
1986: T Hraba; Zbigniew Wieczorek; Maria Janusz; Józef Lisowski; Michal Zimecki
Effect of proline-rich polypeptide on experimental autoimmune response to erythrocytes.
Archivum immunologiae et therapiae experimentalis 1986;34(4):437-43.
1986: Maria Janusz; K Starościk; Michal Zimecki; Zbigniew Wieczorek; Józef Lisowski
A proline-rich polypeptide (PRP) with immunoregulatory properties isolated from ovine colostrum. Murine thymocytes have on their surface a receptor specific for PRP.
Archivum immunologiae et therapiae experimentalis 1986;34(4):427-36.
1984: Michal Zimecki; Józef Lisowski; T Hrabă; Zbigniew Wieczorek; Maria Janusz; K Starościk
The effect of a proline-rich polypeptide (PRP) on the humoral immune response. I. Distinct effect of PRP on the T cell properties of mouse glass-nonadherent (NAT) and glass-adherent (GAT) thymocytes in thymectomized mice.
Archivum immunologiae et therapiae experimentalis 1984;32(2):191-6.
1984: Zbigniew Wieczorek; Michal Zimecki; Maria Janusz; Józef Lisowski; K Starościk
Cells involved in autologous rosette formation in mice. I. Two different subpopulations of thymocytes regulating autologous rosette formation.
Archivum immunologiae et therapiae experimentalis 1984;32(5):537-41.
1984: Michal Zimecki; Józef Lisowski; T Hrabă; Zbigniew Wieczorek; Maria Janusz; K Starościk
The effect of a proline-rich polypeptide (PRP) on the humoral immune response. II. PRP induces differentiation of helper cells from glass-nonadherent thymocytes (NAT) and suppressor cells from glass-adherent thymocytes (GAT).
Archivum immunologiae et therapiae experimentalis 1984;32(2):197-201.
1983: K Starościk; Maria Janusz; Michal Zimecki; Zbigniew Wieczorek; Józef Lisowski
Immunologically active nonapeptide fragment of a proline-rich polypeptide from ovine colostrum: amino acid sequence and immunoregulatory properties.
Molecular immunology 1983;20(12):1277-82.
1983: Maria Janusz; K Starościk; W Gorczyca; Zbigniew Wieczorek; Józef Lisowski
Guinea-pig peritoneal macrophage receptor for IgG--II. Purification of the receptor and its partial characterization.
Molecular immunology 1983;20(11):1149-55.
1983: Michal Zimecki; K Starościk; Maria Janusz; Józef Lisowski; Zbigniew Wieczorek
Effect of PRP on autologous rosette formation in mice.
Archivum immunologiae et therapiae experimentalis 1983;31(1):7-13.
1983: Michal Zimecki; K Starościk; Maria Janusz; Józef Lisowski; Zbigniew Wieczorek
The inhibitory activity of a proline-rich polypeptide (PRP) on the immune response to polyvinylpyrrolidone (PVP).
Archivum immunologiae et therapiae experimentalis 1983;31(6):895-903.
1982: Michal Zimecki; Maria Janusz; K Starościk; Józef Lisowski; Zbigniew Wieczorek
Effect of proline-rich polypeptide on donor cells in graft-versus-host reaction.
Immunology 1982;47(1):141-7.
1981: Maria Janusz; K Starościk; Michal Zimecki; Zbigniew Wieczorek; Józef Lisowski
Chemical and physical characterization of a proline-rich polypeptide from sheep colostrum.
The Biochemical journal 1981;199(1):9-15.
1980: Maria Janusz; Maciej Ugorski; J Mikulska; K Starościk; Zbigniew Wieczorek; Józef Lisowski
Studies on properties of guinea pig peritoneal macrophage Fc receptor.
Archivum immunologiae et therapiae experimentalis 1980;28(2):275-85.