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Pekka Jarho

Research Profile

Concepts & Ideas

Chemicals & Drugs

Procedures

Living Beings

Rabbits

Occupations

Chemistry, Pharmaceutical

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Publications

TOP 3
Ruut Kaartama; Hannu Kokki; Marko Lehtonen; Veli-Pekka Ranta; Jouko Savolainen; Kirsi Toljamo; Elina Turunen; Kristiina Järvinen; Pekka Jarho
The effect of hydroxypropyl-beta-cyclodextrin and sucrose on the sublingual absorption of midazolam in rabbits.
Elina Turunen; Janne Mannila; Riikka Laitinen; Joakim Riikonen; Vesa-Pekka Lehto; Tomi Järvinen; Jarkko Ketolainen; Kristiina Järvinen; Pekka Jarho
Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits.
Riikka Laitinen; Jani Lahtinen; Pertti Silfsten; Erik Vartiainen; Pekka Jarho; Jarkko Ketolainen
An optical method for continuous monitoring of the dissolution rate of pharmaceutical powders.

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All Publications

2012: Ruut Kaartama; Hannu Kokki; Marko Lehtonen; Veli-Pekka Ranta; Jouko Savolainen; Kirsi Toljamo; Elina Turunen; Kristiina Järvinen; Pekka Jarho
The effect of hydroxypropyl-beta-cyclodextrin and sucrose on the sublingual absorption of midazolam in rabbits.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;81(1):178-83.
2011: Elina Turunen; Janne Mannila; Riikka Laitinen; Joakim Riikonen; Vesa-Pekka Lehto; Tomi Järvinen; Jarkko Ketolainen; Kristiina Järvinen; Pekka Jarho
Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits.
The Journal of pharmacy and pharmacology 2011;63(1):19-25.
2010: Riikka Laitinen; Jani Lahtinen; Pertti Silfsten; Erik Vartiainen; Pekka Jarho; Jarkko Ketolainen
An optical method for continuous monitoring of the dissolution rate of pharmaceutical powders.
Journal of pharmaceutical and biomedical analysis 2010;52(2):181-9.
2010: Jeffrey N Hemenway; Pekka Jarho; John T Henri; Sajiv K Nair; David VanderVelde; Gunda I Georg; Valentino J Stella
Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.
Journal of pharmaceutical sciences 2010;99(4):1810-25.
2009: Janne Mannila; Kristiina Järvinen; Jukka Holappa; Laura Matilainen; Seppo Auriola; Pekka Jarho
Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate.
International journal of pharmaceutics 2009;381(1):19-24.
2009: Laura Matilainen; Sirkka Liisa Maunu; Jari Pajander; Seppo Auriola; Ilpo Jääskeläinen; Kim Lambertsen Larsen; Tomi Järvinen; Pekka Jarho
The stability and dissolution properties of solid glucagon/gamma-cyclodextrin powder.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;36(4-5):412-20.
2008: Elina Turunen; Marko Lehtonen; Tomi Järvinen; Pekka Jarho
Development and validation of a gas chromatographic-mass spectrometric method for quantitative determination of perphenazine in rabbit plasma after sublingual administration.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;872(1-2):51-7.
2008: Laura Matilainen; Kim Lambertsen Larsen; Reinhard Wimmer; Pekka Keski-Rahkonen; Seppo Auriola; Tomi Järvinen; Pekka Jarho
The effect of cyclodextrins on chemical and physical stability of glucagon and characterization of glucagon/gamma-CD inclusion complexes.
Journal of pharmaceutical sciences 2008;97(7):2720-9.
2008: Tarja Toropainen; Pekka Jarho; Marko Lehtonen; Pekka Keski-Rahkonen; Heli Raatikainen; Tomi Järvinen
Quantitative analysis of natural cyclodextrins by high-performance liquid chromatography with pulsed amperometric detection: application to cell permeation study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;867(1):90-8.
2008: Laura Matilainen; Tarja Toropainen; Henna Vihola; Jouni Hirvonen; Tomi Järvinen; Pekka Jarho; Kristiina Järvinen
In vitro toxicity and permeation of cyclodextrins in Calu-3 cells.
Journal of controlled release : official journal of the Controlled Release Society 2008;126(1):10-6.
2007: Tarja Toropainen; Teemu Heikkilä; Jukka Leppänen; Laura Matilainen; Sitaram P Velaga; Pekka Jarho; Johan Carlfors; Vesa-Pekka Lehto; Tomi Järvinen; Kristiina Järvinen
Crystal structure changes of gamma-cyclodextrin after the SEDS process in supercritical carbon dioxide affect the dissolution rate of complexed budesonide.
Pharmaceutical research 2007;24(6):1058-66.
2007: Janne Mannila; Tomi Järvinen; Kristiina Järvinen; Pekka Jarho
Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol.
Journal of pharmaceutical sciences 2007;96(2):312-9.
2006: Tarja Toropainen; Sitaram P Velaga; Teemu Heikkilä; Laura Matilainen; Pekka Jarho; Johan Carlfors; Vesa-Pekka Lehto; Tomi Järvinen; Kristiina Järvinen
Preparation of budesonide/gamma-cyclodextrin complexes in supercritical fluids with a novel SEDS method.
Journal of pharmaceutical sciences 2006;95(10):2235-45.
2006: Laura Matilainen; Kristiina Järvinen; Tarja Toropainen; E Näsi; Seppo Auriola; Tomi Järvinen; Pekka Jarho
In vitro evaluation of the effect of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin A.
International journal of pharmaceutics 2006;318(1-2):41-8.
2006: Janne Mannila; Tomi Järvinen; Kristiina Järvinen; Jussi Tervonen; Pekka Jarho
Sublingual administration of Delta9-tetrahydrocannabinol/beta-cyclodextrin complex increases the bioavailability of Delta9-tetrahydrocannabinol in rabbits.
Life sciences 2006;78(17):1911-4.
2005: Janne Mannila; Tomi Järvinen; Kristiina Järvinen; Mika P Tarvainen; Pekka Jarho
Effects of RM-beta-CD on sublingual bioavailability of Delta9-tetrahydrocannabinol in rabbits.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(1):71-7.
2005: Thorsteinn Loftsson; Pekka Jarho; Már Másson; Tomi Järvinen
Cyclodextrins in drug delivery.
Expert opinion on drug delivery 2005;2(2):335-51.
2004: Janne Mannila; Marko Lehtonen; Tomi Järvinen; Pekka Jarho
Determination of Delta9-tetrahydrocannabinol from rabbit plasma by gas chromatography-mass spectrometry using two ionization techniques.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;810(2):283-90.
2003: Tarja Kinnarinen; Pekka Jarho; Kristiina Järvinen; Tomi Järvinen
Pulmonary deposition of a budesonide/gamma-cyclodextrin complex in vitro.
Journal of controlled release : official journal of the Controlled Release Society 2003;90(2):197-205.
2001: Eero Suihko; Ossi Korhonen; Tomi Järvinen; Jarkko Ketolainen; Pekka Jarho; Ensio Laine; Timo Petteri Paronen
Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin.
International journal of pharmaceutics 2001;215(1-2):137-45.
1998: Jouko Savolainen; Kristiina Järvinen; Hannu Taipale; Pekka Jarho; Thorsteinn Loftsson; Tomi Järvinen
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms.
Pharmaceutical research 1998;15(11):1696-701.
1998: Pekka Jarho; David W Pate; R Brenneisen; Tomi Järvinen
Hydroxypropyl-beta-cyclodextrin and its combination with hydroxypropyl-methylcellulose increases aqueous solubility of delta9-tetrahydrocannabinol.
Life sciences 1998;63(26):PL381-4.
1997: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; V Mahadevan; Tomi Järvinen
Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits.
Pharmaceutical research 1997;14(12):1738-43.
1996: Pekka Jarho; Kristiina Järvinen; Arto Urtti; Valentino J Stella; Tomi Järvinen
Modified beta-cyclodextrin (SBE7-beta-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits.
The Journal of pharmacy and pharmacology 1996;48(3):263-9.
1996: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; M Fich; V Mahadevan; Tomi Järvinen
Effects of topical anandamides on intraocular pressure in normotensive rabbits.
Life sciences 1996;58(21):1849-60.
1996: Pekka Jarho; Arto Urtti; Kristiina Järvinen; David W Pate; Tomi Järvinen
Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide.
Life sciences 1996;58(10):PL 181-5.
1995: Pekka Jarho; Arto Urtti; Tomi Järvinen
Hydroxypropyl-beta-cyclodextrin increases the aqueous solubility and stability of pilocarpine prodrugs.
Pharmaceutical research 1995;12(9):1371-5.
1995: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; Tomi Järvinen
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits.
Current eye research 1995;14(9):791-7.