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Amjad Javed

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Christopher R Dowdy; Ronglin Xie; Dana Frederick; Sadiq Hussain; Sayyed K Zaidi; Diana Vradii; Amjad Javed; Xiangen Li; Stephen N Jones; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.
Sayyed K Zaidi; Ricardo F Medina; Shirwin M Pockwinse; Rachit Bakshi; Krishna P Kota; Syed A Ali; Daniel W Young; Jeffrey A Nickerson; Amjad Javed; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Subnuclear localization and intranuclear trafficking of transcription factors.
Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel W Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.

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All Publications

2010: Christopher R Dowdy; Ronglin Xie; Dana Frederick; Sadiq Hussain; Sayyed K Zaidi; Diana Vradii; Amjad Javed; Xiangen Li; Stephen N Jones; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.
Human molecular genetics 2010;19(6):1048-57.
2010: Sayyed K Zaidi; Ricardo F Medina; Shirwin M Pockwinse; Rachit Bakshi; Krishna P Kota; Syed A Ali; Daniel W Young; Jeffrey A Nickerson; Amjad Javed; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Subnuclear localization and intranuclear trafficking of transcription factors.
Methods in molecular biology (Clifton, N.J.) 2010;647():77-93.
2009: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel W Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.
Annals of the New York Academy of Sciences 2009;1155():4-14.
2009: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel W Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):1-6.
2009: Yang Lou; Amjad Javed; Sadiq Hussain; Jennifer Colby; Dana Frederick; Jitesh Pratap; Ronglin Xie; Tripti Gaur; Andre J van Wijnen; Stephen N Jones; Gary S Stein; Jane B Lian; Janet L Stein
A Runx2 threshold for the cleidocranial dysplasia phenotype.
Human molecular genetics 2009;18(3):556-68.
2009: Amjad Javed; Faiza Afzal; Jong-Sup Bae; Soraya Gutierrez; Kaleem Zaidi; Jitesh Pratap; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.
Cells, tissues, organs 2009;189(1-4):133-7.
2008: Nadiya M Teplyuk; Mario Galindo; Viktor I Teplyuk; Jitesh Pratap; Daniel Young; David Lapointe; Amjad Javed; Janet L Stein; Jane B Lian; Gary S Stein; Andre J van Wijnen
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
The Journal of biological chemistry 2008;283(41):27585-97.
2008: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer.
Journal of cellular biochemistry 2008;104(6):2016-26.
2008: Amjad Javed; Jong-Sup Bae; Faiza Afzal; Soraya Gutierrez; Jitesh Pratap; Sayyed K Zaidi; Yang Lou; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.
The Journal of biological chemistry 2008;283(13):8412-22.
2008: Shirwin M Pockwinse; Sayyed K Zaidi; Ricardo F Medina; Rachit Bakshi; Krishna P Kota; Syed A Ali; Daniel Young; Jeffery A Nickerson; Amjad Javed; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ nuclear organization of regulatory machinery.
Methods in molecular biology (Clifton, N.J.) 2008;455():239-59.
2008: Margaretha van der Deen; Mohammad Q Hassan; Jitesh Pratap; Nadiya M Teplyuk; Daniel Young; Amjad Javed; Sayyed K Zaidi; Jane B Lian; Martin Montecino; Janet L Stein; Gary S Stein; Andre J van Wijnen
Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.
Methods in molecular biology (Clifton, N.J.) 2008;455():165-76.
2007: Sayyed K Zaidi; Daniel Young; Amjad Javed; Jitesh Pratap; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Nuclear microenvironments in biological control and cancer.
Nature reviews. Cancer 2007;7(6):454-63.
2007: Daniel Young; Mohammad Q Hassan; Xiao-Qing Yang; Mario Galindo; Amjad Javed; Sayyed K Zaidi; Paul Furcinitti; David Lapointe; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3189-94.
2007: Jong-Sup Bae; Soraya Gutierrez; Radhika Narla; Jitesh Pratap; Rajitha Devados; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian; Amjad Javed
Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
Journal of cellular biochemistry 2007;100(2):434-49.
2007: Daniel Young; Mohammad Q Hassan; Jitesh Pratap; Mario Galindo; Sayyed K Zaidi; Suk-hee Lee; Xiaoqing Yang; Ronglin Xie; Amjad Javed; Jean M Underwood; Paul Furcinitti; Anthony N Imbalzano; Sheldon Penman; Jeffrey A Nickerson; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.
Nature 2007;445(7126):442-6.
2007: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Amjad Javed; Martin Montecino; Je-Yong Choi; Diana Vradii; Sayyed K Zaidi; Jitesh Pratap; Daniel Young
Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer.
Advances in enzyme regulation 2007;47():242-50.
2006: Mohammad Q Hassan; Rahul S Tare; Suk Hee Lee; Matthew Mandeville; Maria I Morasso; Amjad Javed; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.
The Journal of biological chemistry 2006;281(52):40515-26.
2006: Jitesh Pratap; Jane B Lian; Amjad Javed; George L Barnes; Andre J van Wijnen; Janet L Stein; Gary S Stein
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.
Cancer metastasis reviews 2006;25(4):589-600.
2006: Sayyed K Zaidi; Amjad Javed; Jitesh Pratap; Tania M Schroeder; Jennifer J Westendorf; Jane B Lian; Andre J van Wijnen; Gary S Stein; Janet L Stein
Alterations in intranuclear localization of Runx2 affect biological activity.
Journal of cellular physiology 2006;209(3):935-42.
2006: Jane B Lian; Gary S Stein; Amjad Javed; Andre J van Wijnen; Janet L Stein; Martin Montecino; Mohammad Q Hassan; Tripti Gaur; Christopher J Lengner; Daniel Young
Networks and hubs for the transcriptional control of osteoblastogenesis.
Reviews in endocrine & metabolic disorders 2006;7(1-2):1-16.
2006: Shirwin M Pockwinse; Arun Rajgopal; Daniel Young; Khwaja A Mujeeb; Jeffrey A Nickerson; Amjad Javed; Sambra Redick; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Stephen J Doxsey
Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.
Journal of cellular physiology 2006;206(2):354-62.
2005: Xiangen Li; Diana Vradii; Soraya Gutierrez; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Amjad Javed
Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.
Journal of cellular biochemistry 2005;96(4):795-809.
2005: Jitesh Pratap; Amjad Javed; Lucia R Languino; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.
Molecular and cellular biology 2005;25(19):8581-91.
2005: Tripti Gaur; Christopher J Lengner; Hayk Hovhannisyan; Ramesh A Bhat; Peter V N Bodine; Barry S Komm; Amjad Javed; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.
The Journal of biological chemistry 2005;280(39):33132-40.
2005: Laura H Saltman; Amjad Javed; John Ribadeneyra; Sadiq Hussain; Daniel Young; Philip Osdoby; Alla Amcheslavsky; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian; Zvi Bar-Shavit
Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.
Journal of cellular physiology 2005;204(3):871-80.
2005: Faiza Afzal; Jitesh Pratap; Kosei Ito; Yoshiaki Ito; Janet L Stein; Andre J van Wijnen; Gary S Stein; Jane B Lian; Amjad Javed
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.
Journal of cellular physiology 2005;204(1):63-72.
2005: Daniel Young; Jitesh Pratap; Amjad Javed; Brian Weiner; Yasuyuki Ohkawa; Andre J van Wijnen; Martin Montecino; Gary S Stein; Janet L Stein; Anthony N Imbalzano; Jane B Lian
SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
Journal of cellular biochemistry 2005;94(4):720-30.
2005: Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap; Amjad Javed; Martin Montecino; Janet L Stein; Andre J van Wijnen; Jane B Lian; Gary S Stein
The dynamic organization of gene-regulatory machinery in nuclear microenvironments.
EMBO reports 2005;6(2):128-33.
2005: Amjad Javed; George L Barnes; Jitesh Pratap; Tomasz Antkowiak; Louis C Gerstenfeld; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1454-9.
2005: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Amjad Javed; Martin Montecino; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap
Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer.
Advances in enzyme regulation 2005;45():136-54.
2004: Soraya Gutierrez; Jilin Liu; Amjad Javed; Martin Montecino; Gary S Stein; Jane B Lian; Janet L Stein
The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain.
The Journal of biological chemistry 2004;279(42):43581-8.
2004: Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap; Amjad Javed; Martin Montecino; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control.
The Journal of biological chemistry 2004;279(42):43363-6.
2004: Mohammad Q Hassan; Amjad Javed; Maria I Morasso; Jeremy Karlin; Martin Montecino; Andre J van Wijnen; Gary S Stein; Janet L Stein; Jane B Lian
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.
Molecular and cellular biology 2004;24(20):9248-61.
2004: Daniel Young; Sayyed K Zaidi; Paul Furcinitti; Amjad Javed; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.
Journal of cell science 2004;117(Pt 21):4889-96.
2004: George L Barnes; Kerri E Hebert; Mohammad Kamal; Amjad Javed; Thomas A Einhorn; Jane B Lian; Gary S Stein; Louis C Gerstenfeld
Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.
Cancer research 2004;64(13):4506-13.
2004: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Martin Montecino; Amjad Javed; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Shirwin M Pockwinse
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression.
Oncogene 2004;23(24):4315-29.
2004: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Amjad Javed; Martin Montecino; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Soraya Gutierrez; Shirwin M Pockwinse
Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation.
Journal of cellular biochemistry 2004;91(2):287-302.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 2004;285():63-7.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.
Methods in molecular biology (Clifton, N.J.) 2004;285():57-62.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay.
Methods in molecular biology (Clifton, N.J.) 2004;285():45-55.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Chromatin immunoprecipitation.
Methods in molecular biology (Clifton, N.J.) 2004;285():41-4.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Analysis of in vivo gene expression using epitope-tagged proteins.
Methods in molecular biology (Clifton, N.J.) 2004;285():37-40.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Immunofluorescence analysis using epitope-tagged proteins: in vitro system.
Methods in molecular biology (Clifton, N.J.) 2004;285():33-6.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling.
Methods in molecular biology (Clifton, N.J.) 2004;285():29-31.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ immunofluorescence analysis: immunofluorescence microscopy.
Methods in molecular biology (Clifton, N.J.) 2004;285():23-8.
2004: Gary S Stein; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Amjad Javed; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Shirwin M Pockwinse
Nuclear microenvironments: an architectural platform for the convergence and integration of transcriptional regulatory signals.
European journal of histochemistry : EJH 2004;48(1):65-76.
2004: Jane B Lian; Amjad Javed; Sayyed K Zaidi; Christopher J Lengner; Martin Montecino; Andre J van Wijnen; Janet L Stein; Gary S Stein
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors.
Critical reviews in eukaryotic gene expression 2004;14(1-2):1-41.
2003: Sayyed K Zaidi; Daniel Young; Shirwin M Pockwinse; Amjad Javed; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14852-7.
2003: Gary S Stein; Sayyed K Zaidi; Corey D Braastad; Martin Montecino; Andre J van Wijnen; Je-Yong Choi; Janet L Stein; Jane B Lian; Amjad Javed
Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.
Trends in cell biology 2003;13(11):584-92.
2003: Jane B Lian; Eva Balint; Amjad Javed; Hicham Drissi; Regan Vitti; Edward J Quinlan; Lina Zhang; Andre J van Wijnen; Janet L Stein; Nancy Speck; Gary S Stein
Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.
Journal of cellular physiology 2003;196(2):301-11.
2003: George L Barnes; Amjad Javed; Sylvan M Waller; Mohammad H Kamal; Kerri E Hebert; Mohammad Q Hassan; Akeila Bellahcene; Andre J van Wijnen; Marian F Young; Jane B Lian; Gary S Stein; Louis C Gerstenfeld
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells.
Cancer research 2003;63(10):2631-7.
2003: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Martin Montecino; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Amjad Javed; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young
Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer.
Blood cells, molecules & diseases 2003;30(2):170-6.
2003: Gary S Stein; Jane B Lian; Janet L Stein; André J van Wijnen; Martin Montecino; Amjad Javed; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young
Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.
Journal of cellular biochemistry 2003;88(2):340-55.
2003: Gary S Stein; Jane B Lian; Martin Montecino; Janet L Stein; Andre J van Wijnen; Amjad Javed; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young; Shirwin M Pockwinse
Nuclear microenvironments support physiological control of gene expression.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(5):527-36.
2003: Jane B Lian; Janet L Stein; Gary S Stein; Andre J van Wijnen; Martin Montecino; Amjad Javed; Soraya Gutierrez; Jiali Shen; Sayyed K Zaidi; Hicham Drissi
Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions.
Connective tissue research 2003;44 Suppl 1():141-8.
2002: Kimberly S Harrington; Amjad Javed; Hicham Drissi; Sandra McNeil; Jane B Lian; Janet L Stein; Andre J van Wijnen; Yu-Li Wang; Gary S Stein
Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.
Journal of cell science 2002;115(Pt 21):4167-76.
2002: Soraya Gutierrez; Amjad Javed; Daniel K Tennant; Monique van Rees; Martin Montecino; Gary S Stein; Janet L Stein; Jane B Lian
CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.
The Journal of biological chemistry 2002;277(2):1316-23.
2001: Sayyed K Zaidi; Amjad Javed; Je-Yong Choi; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene.
Journal of cell science 2001;114(Pt 17):3093-102.
2001: C Banerjee; Amjad Javed; Je-Yong Choi; J Green; V Rosen; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.
Endocrinology 2001;142(9):4026-39.
2001: Je-Yong Choi; Jitesh Pratap; Amjad Javed; Sayyed K Zaidi; L Xing; Eva Balint; S Dalamangas; B Boyce; Andre J van Wijnen; Jane B Lian; Janet L Stein; Stephen N Jones; Gary S Stein
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8650-5.
2001: Amjad Javed; George L Barnes; B O Jasanya; Janet L Stein; Louis C Gerstenfeld; Jane B Lian; Gary S Stein
runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins.
Molecular and cellular biology 2001;21(8):2891-905.
2001: M Prince; C Banerjee; Amjad Javed; J Green; Jane B Lian; Gary S Stein; Peter V N Bodine; Barry S Komm
Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts.
Journal of cellular biochemistry 2001;80(3):424-40.
2000: Sandra McNeil; Amjad Javed; Kimberly S Harrington; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies.
Journal of cellular biochemistry 2000;79(1):103-12.
2000: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Martin Montecino; Je Choi; Kaleem Zaidi; Amjad Javed
Intranuclear trafficking of transcription factors: implications for biological control.
Journal of cell science 2000;113 ( Pt 14)():2527-33.
2000: Amjad Javed; B Guo; Scott W Hiebert; Je-Yong Choi; J Green; S C Zhao; M A Osborne; S Stifani; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription.
Journal of cell science 2000;113 ( Pt 12)():2221-31.
2000: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Martin Montecino; Kaleem Zaidi; Amjad Javed
Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.
Journal of cellular biochemistry. Supplement 2000;Suppl 35():84-92.
1999: M F van Gurp; Jitesh Pratap; Mai X Luong; Amjad Javed; H Hoffmann; Antonio Giordano; Janet L Stein; E J Neufeld; Jane B Lian; Gary S Stein; Andre J van Wijnen
The CCAAT displacement protein/cut homeodomain protein represses osteocalcin gene transcription and forms complexes with the retinoblastoma protein-related protein p107 and cyclin A.
Cancer research 1999;59(23):5980-8.
1999: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Amjad Javed; Sandra McNeil; Shirwin M Pockwinse
Insight into regulatory factor targeting to transcriptionally active subnuclear sites.
Experimental cell research 1999;253(1):110-6.
1999: L Tang; B Guo; Amjad Javed; Je-Yong Choi; Scott W Hiebert; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; G Wayne Zhou
Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2.
The Journal of biological chemistry 1999;274(47):33580-6.
1999: Amjad Javed; S Gutierrez; Martin Montecino; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.
Molecular and cellular biology 1999;19(11):7491-500.