Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Jonathan Javitch

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Physiology

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
21
Shi, Lei
17
Galli, Aurelio
13
Gether, Ulrik
10
Ballesteros, Juan
10
WEINSTEIN, HAREL
9
Chen, J
9
Ferrer, Jasmine
7
Khoshbouei, Habibeh
7
Liapakis, George
7
Loland, Claus
5
Shippenberg, Toni
5
Kahlig, Kristopher
5
Beuming, Thijs
4
Filizola, Marta
4
Dipace, Concetta

Sign-in to see all Coauthors

Publications

TOP 3
Sohy Denis; Yano Hideaki; de Nadai Patricia; Urizar Eneko; Guillabert Aude; Javitch Jonathan A; Parmentier Marc; Springael Jean-Yves
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
Gaskill Peter J; Calderon Tina M; Luers Aimée J; Eugenin Eliseo A; Javitch Jonathan A; Berman Joan W
Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse.
Han Yang; Moreira Irina S; Urizar Eneko; Weinstein Harel; Javitch Jonathan A
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Jonathan Javitch (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Sohy Denis; Yano Hideaki; de Nadai Patricia; Urizar Eneko; Guillabert Aude; Javitch Jonathan A; Parmentier Marc; Springael Jean-Yves
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
The Journal of biological chemistry 2009;284(45):31270-9.
2009: Gaskill Peter J; Calderon Tina M; Luers Aimée J; Eugenin Eliseo A; Javitch Jonathan A; Berman Joan W
Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse.
The American journal of pathology 2009;175(3):1148-59.
2009: Han Yang; Moreira Irina S; Urizar Eneko; Weinstein Harel; Javitch Jonathan A
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.
Nature chemical biology 2009;5(9):688-95.
2009: Fontana Andréia C K; Sonders Mark S; Pereira-Junior Olavo S; Knight Matty; Javitch Jonathan A; Rodrigues Vanderlei; Amara Susan G; Mortensen Ole V
Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin.
European journal of pharmacology 2009;616(1-3):48-57.
2009: Cui Mei; Aras Radha; Christian Whitney V; Rappold Phillip M; Hatwar Mamata; Panza Joseph; Jackson-Lewis Vernice; Javitch Jonathan A; Ballatori Nazzareno; Przedborski Serge; Tieu Kim
The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):8043-8.
2009: Namkung Yoon; Dipace Concetta; Javitch Jonathan A; Sibley David R
G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.
The Journal of biological chemistry 2009;284(22):15038-51.
2009: Quick Matthias; Winther Anne-Marie Lund; Shi Lei; Nissen Poul; Weinstein Harel; Javitch Jonathan A
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5563-8.
2009: Ferré Sergi; Baler Ruben; Bouvier Michel; Caron Marc G; Devi Lakshmi A; Durroux Thierry; Fuxe Kjell; George Susan R; Javitch Jonathan A; Lohse Martin J; Mackie Ken; Milligan Graeme; Pfleger Kevin D G; Pin Jean-Philippe; Volkow Nora D; Waldhoer Maria; Woods Amina S; Franco Rafael
Building a new conceptual framework for receptor heteromers.
Nature chemical biology 2009;5(3):131-4.
2009: Guptaroy Bipasha; Zhang Minjia; Bowton Erica; Binda Francesca; Shi Lei; Weinstein Harel; Galli Aurelio; Javitch Jonathan A; Neubig Richard R; Gnegy Margaret E
A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.
Molecular pharmacology 2009;75(3):514-24.
2009: Goodwin J Shawn; Larson Gaynor A; Swant Jarod; Sen Namita; Javitch Jonathan A; Zahniser Nancy R; De Felice Louis J; Khoshbouei Habibeh
Amphetamine and methamphetamine differentially affect dopamine transporters in vitro and in vivo.
The Journal of biological chemistry 2009;284(5):2978-89.
2008: Binda Francesca; Dipace Concetta; Bowton Erica; Robertson Sabrina D; Lute Brandon J; Fog Jacob U; Zhang Minjia; Sen Namita; Colbran Roger J; Gnegy Margaret E; Gether Ulrik; Javitch Jonathan A; Erreger Kevin; Galli Aurelio
Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux.
Molecular pharmacology 2008;74(4):1101-8.
2008: Guo Wen; Urizar Eneko; Kralikova Michaela; Mobarec Juan Carlos; Shi Lei; Filizola Marta; Javitch Jonathan A
Dopamine D2 receptors form higher order oligomers at physiological expression levels.
The EMBO journal 2008;27(17):2293-304.
2008: Lieberman Jeffrey A; Javitch Jonathan A; Moore Holly
Cholinergic agonists as novel treatments for schizophrenia: the promise of rational drug development for psychiatry.
The American journal of psychiatry 2008;165(8):931-6.
2008: Lute Brandon J; Khoshbouei Habibeh; Saunders Christine; Sen Namita; Lin Richard Z; Javitch Jonathan A; Galli Aurelio
PI3K signaling supports amphetamine-induced dopamine efflux.
Biochemical and biophysical research communications 2008;372(4):656-61.
2008: Beuming Thijs; Kniazeff Julie; Bergmann Marianne L; Shi Lei; Gracia Luis; Raniszewska Klaudia; Newman Amy Hauck; Javitch Jonathan A; Weinstein Harel; Gether Ulrik; Loland Claus J
The binding sites for cocaine and dopamine in the dopamine transporter overlap.
Nature neuroscience 2008;11(7):780-9.
2008: Shi Lei; Quick Matthias; Zhao Yongfang; Weinstein Harel; Javitch Jonathan A
The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.
Molecular cell 2008;30(6):667-77.
2008: Klewe Ib V; Nielsen Søren M; Tarpø Louise; Urizar Eneko; Dipace Concetta; Javitch Jonathan A; Gether Ulrik; Egebjerg Jan; Christensen Kenneth V
Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling.
Neuropharmacology 2008;54(8):1215-22.
2008: Kniazeff Julie; Shi Lei; Loland Claus J; Javitch Jonathan A; Weinstein Harel; Gether Ulrik
An intracellular interaction network regulates conformational transitions in the dopamine transporter.
The Journal of biological chemistry 2008;283(25):17691-701.
2008: Erreger Kevin; Grewer Christof; Javitch Jonathan A; Galli Aurelio
Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(4):976-89.
2007: Zapata Agustin; Kivell Bronwyn; Han Yang; Javitch Jonathan A; Bolan Elizabeth A; Kuraguntla David; Jaligam Vanaja; Oz Murat; Jayanthi Lankupalle D; Samuvel Devadoss J; Ramamoorthy Sammanda; Shippenberg Toni S
Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors.
The Journal of biological chemistry 2007;282(49):35842-54.
2007: Zomot Elia; Bendahan Annie; Quick Matthias; Zhao Yongfang; Javitch Jonathan A; Kanner Baruch I
Mechanism of chloride interaction with neurotransmitter:sodium symporters.
Nature 2007;449(7163):726-30.
2007: Bolan Elizabeth A; Kivell Bronwyn; Jaligam Vanaja; Oz Murat; Jayanthi Lankupalle D; Han Yang; Sen Namita; Urizar Eneki; Gomes Ivone; Devi Lakshmi A; Ramamoorthy Sammanda; Javitch Jonathan A; Zapata Agustin; Shippenberg Toni S
D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism.
Molecular pharmacology 2007;71(5):1222-32.
2007: Pin Jean-Philippe; Neubig Richard; Bouvier Michel; Devi Lakshmi; Filizola Marta; Javitch Jonathan A; Lohse Martin J; Milligan Graeme; Palczewski Krzysztof; Parmentier Marc; Spedding Michael
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.
Pharmacological reviews 2007;59(1):5-13.
2007: Wei Y; Williams J M; Dipace C; Sung U; Javitch J A; Galli A; Saunders C
Dopamine transporter activity mediates amphetamine-induced inhibition of Akt through a Ca2+/calmodulin-dependent kinase II-dependent mechanism.
Molecular pharmacology 2007;71(3):835-42.
2007: Quick Matthias; Javitch Jonathan A
Monitoring the function of membrane transport proteins in detergent-solubilized form.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3603-8.
2007: Urban Jonathan D; Clarke William P; von Zastrow Mark; Nichols David E; Kobilka Brian; Weinstein Harel; Javitch Jonathan A; Roth Bryan L; Christopoulos Arthur; Sexton Patrick M; Miller Keith J; Spedding Michael; Mailman Richard B
Functional selectivity and classical concepts of quantitative pharmacology.
The Journal of pharmacology and experimental therapeutics 2007;320(1):1-13.
2007: Skrabanek Lucy; Murcia Marta; Bouvier Michel; Devi Lakshmi; George Susan R; Lohse Martin J; Milligan Graeme; Neubig Richard; Palczewski Krzysztof; Parmentier Marc; Pin Jean-Philippe; Vriend Gerrit; Javitch Jonathan A; Campagne Fabien; Filizola Marta
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base.
BMC bioinformatics 2007;8():177.
2006: Beuming Thijs; Shi Lei; Javitch Jonathan A; Weinstein Harel
A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.
Molecular pharmacology 2006;70(5):1630-42.
2006: Quick Matthias; Yano Hideaki; Goldberg Naomi R; Duan Lihua; Beuming Thijs; Shi Lei; Weinstein Harel; Javitch Jonathan A
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.
The Journal of biological chemistry 2006;281(36):26444-54.
2006: Fog Jacob U; Khoshbouei Habibeh; Holy Marion; Owens William A; Vaegter Christian Bjerggaard; Sen Namita; Nikandrova Yelyzaveta; Bowton Erica; McMahon Douglas G; Colbran Roger J; Daws Lynette C; Sitte Harald H; Javitch Jonathan A; Galli Aurelio; Gether Ulrik
Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.
Neuron 2006;51(4):417-29.
2006: Kahlig Kristopher M; Lute Brandon J; Wei Yuqiang; Loland Claus J; Gether Ulrik; Javitch Jonathan A; Galli Aurelio
Regulation of dopamine transporter trafficking by intracellular amphetamine.
Molecular pharmacology 2006;70(2):542-8.
2006: Shi Lei; Javitch Jonathan A
A role for information collection, management, and integration in structure-function studies of G-protein coupled receptors.
Current pharmaceutical design 2006;12(14):1771-83.
2005: Guo Wen; Shi Lei; Filizola Marta; Weinstein Harel; Javitch Jonathan A
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(48):17495-500.
2005: Sen Namita; Shi Lei; Beuming Thijs; Weinstein Harel; Javitch Jonathan A
A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.
Neuropharmacology 2005;49(6):780-90.
2005: Kniazeff Julie; Loland Claus Juul; Goldberg Naomi; Quick Matthias; Das Shonit; Sitte Harald H; Javitch Jonathan A; Gether Ulrik
Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8.
Neuropharmacology 2005;49(6):715-23.
2005: Garcia B G; Wei Y; Moron J A; Lin R Z; Javitch J A; Galli A
Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution.
Molecular pharmacology 2005;68(1):102-9.
2005: Sonders Mark S; Quick Matthias; Javitch Jonathan A
How did the neurotransmitter cross the bilayer? A closer view.
Current opinion in neurobiology 2005;15(3):296-304.
2005: Kahlig Kristopher M; Binda Francesca; Khoshbouei Habibeh; Blakely Randy D; McMahon Douglas G; Javitch Jonathan A; Galli Aurelio
Amphetamine induces dopamine efflux through a dopamine transporter channel.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3495-500.
2004: Javitch Jonathan A
The ants go marching two by two: oligomeric structure of G-protein-coupled receptors.
Molecular pharmacology 2004;66(5):1077-82.
2004: Bjerggaard Christian; Fog Jacob U; Hastrup Hanne; Madsen Kenneth; Loland Claus J; Javitch Jonathan A; Gether Ulrik
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(31):7024-36.
2004: Gnegy Margaret E; Khoshbouei Habibeh; Berg Kelly A; Javitch Jonathan A; Clarke William P; Zhang Minjia; Galli Aurelio
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter.
Molecular pharmacology 2004;66(1):137-43.
2004: Liapakis George; Chan Wai Chi; Papadokostaki Maria; Javitch Jonathan A
Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the beta2 adrenergic receptor.
Molecular pharmacology 2004;65(5):1181-90.
2004: Javitch Jonathan A
Finding needles in haystacks.
Nature biotechnology 2004;22(4):394-6.
2004: Khoshbouei Habibeh; Sen Namita; Guptaroy Bipasha; Johnson L 'Aurelle; Lund David; Gnegy Margaret E; Galli Aurelio; Javitch Jonathan A
N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux.
PLoS biology 2004;2(3):E78.
2004: Kahlig Kristopher M; Javitch Jonathan A; Galli Aurelio
Amphetamine regulation of dopamine transport. Combined measurements of transporter currents and transporter imaging support the endocytosis of an active carrier.
The Journal of biological chemistry 2004;279(10):8966-75.
2004: Sitte Harald H; Farhan Hesso; Javitch Jonathan A
Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking.
Molecular interventions 2004;4(1):38-47.
2004: Shi Lei; Javitch Jonathan A
The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):440-5.
2004: Loland Claus Juul; Grånäs Charlotta; Javitch Jonathan A; Gether Ulrik
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.
The Journal of biological chemistry 2004;279(5):3228-38.
2003: Hastrup Hanne; Sen Namita; Javitch Jonathan A
The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs.
The Journal of biological chemistry 2003;278(46):45045-8.
2003: Goldberg Naomi R; Beuming Thijs; Soyer Orkun S; Goldstein Richard A; Weinstein Harel; Javitch Jonathan A
Probing conformational changes in neurotransmitter transporters: a structural context.
European journal of pharmacology 2003;479(1-3):3-12.
2003: Morón José A; Zakharova Irina; Ferrer Jasmine V; Merrill Gerald A; Hope Bruce; Lafer Eileen M; Lin Zhi Cheng; Wang Jia Bei; Javitch Jonathan A; Galli Aurelio; Shippenberg Toni S
Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(24):8480-8.
2003: Park Samuel; Geddes Timothy J; Javitch Jonathan A; Kuhn Donald M
Dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage?
The Journal of biological chemistry 2003;278(31):28736-42.
2003: Androutsellis-Theotokis Andreas; Goldberg Naomi R; Ueda Kenji; Beppu Teruhiko; Beckman Matthew L; Das Shonit; Javitch Jonathan A; Rudnick Gary
Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters.
The Journal of biological chemistry 2003;278(15):12703-9.
2003: Khoshbouei Habibeh; Wang Hongwei; Lechleiter James D; Javitch Jonathan A; Galli Aurelio
Amphetamine-induced dopamine efflux. A voltage-sensitive and intracellular Na+-dependent mechanism.
The Journal of biological chemistry 2003;278(14):12070-7.
2003: Guo Wen; Shi Lei; Javitch Jonathan A
The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.
The Journal of biological chemistry 2003;278(7):4385-8.
2003: Granas Charlotta; Ferrer Jasmine; Loland Claus Juul; Javitch Jonathan A; Gether Ulrik
N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization.
The Journal of biological chemistry 2003;278(7):4990-5000.
2002: Shi Lei; Liapakis George; Xu Rui; Guarnieri Frank; Ballesteros Juan A; Javitch Jonathan A
Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch.
The Journal of biological chemistry 2002;277(43):40989-96.
2002: Norgaard-Nielsen Kristine; Norregaard Lene; Hastrup Hanne; Javitch Jonathan A; Gether Ulrik
Zn(2+) site engineering at the oligomeric interface of the dopamine transporter.
FEBS letters 2002;524(1-3):87-91.
2002: Park Samuel U; Ferrer Jasmine V; Javitch Jonathan A; Kuhn Donald M
Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4399-405.
2002: Carvelli Lucia; Morón José A; Kahlig Kristopher M; Ferrer Jasmine V; Sen Namita; Lechleiter James D; Leeb-Lundberg L M Fredrik; Merrill Gerald; Lafer Eileen M; Ballou Lisa M; Shippenberg Toni S; Javitch Jonathan A; Lin Richard Z; Galli Aurelio
PI 3-kinase regulation of dopamine uptake.
Journal of neurochemistry 2002;81(4):859-69.
2002: Daws Lynette C; Callaghan Paul D; Morón José A; Kahlig Kris M; Shippenberg Toni S; Javitch Jonathan A; Galli Aurelio
Cocaine increases dopamine uptake and cell surface expression of dopamine transporters.
Biochemical and biophysical research communications 2002;290(5):1545-50.
2002: Shi Lei; Javitch Jonathan A
The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop.
Annual review of pharmacology and toxicology 2002;42():437-67.
2002: Javitch Jonathan A; Shi Lei; Liapakis George
Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors.
Methods in enzymology 2002;343():137-56.
2001: Shi L; Simpson M M; Ballesteros J A; Javitch J A
The first transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle.
Biochemistry 2001;40(41):12339-48.
2001: Hastrup H; Karlin A; Javitch J A
Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10055-60.
2001: Reith M E; Berfield J L; Wang L C; Ferrer J V; Javitch J A
The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter.
The Journal of biological chemistry 2001;276(31):29012-8.
2001: Ballesteros J A; Jensen A D; Liapakis G; Rasmussen S G; Shi L; Gether U; Javitch J A
Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.
The Journal of biological chemistry 2001;276(31):29171-7.
2001: Newman A H; Zou M F; Ferrer J V; Javitch J A
[3H]MFZ 2-12: a novel radioligand for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2001;11(13):1659-61.
2001: Ballesteros J A; Shi L; Javitch J A
Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors.
Molecular pharmacology 2001;60(1):1-19.
2001: Whitehead R E; Ferrer J V; Javitch J A; Justice J B
Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.
Journal of neurochemistry 2001;76(4):1242-51.
2000: Liapakis G; Ballesteros J A; Papachristou S; Chan W C; Chen X; Javitch J A
The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.
The Journal of biological chemistry 2000;275(48):37779-88.
2000: Javitch J A; Shi L; Simpson M M; Chen J; Chiappa V; Visiers I; Weinstein H; Ballesteros J A
The fourth transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle.
Biochemistry 2000;39(40):12190-9.
2000: Saunders C; Ferrer J V; Shi L; Chen J; Merrill G; Lamb M E; Leeb-Lundberg L M; Carvelli L; Javitch J A; Galli A
Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6850-5.
2000: Chen N; Ferrer J V; Javitch J A; Justice J B
Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter.
The Journal of biological chemistry 2000;275(3):1608-14.
1999: Simpson M M; Ballesteros J A; Chiappa V; Chen J; Suehiro M; Hartman D S; Godel T; Snyder L A; Sakmar T P; Javitch J A
Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments.
Molecular pharmacology 1999;56(6):1116-26.
1999: Rasmussen S G; Jensen A D; Liapakis G; Ghanouni P; Javitch J A; Gether U
Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6.
Molecular pharmacology 1999;56(1):175-84.
1999: Javitch J A; Ballesteros J A; Chen J; Chiappa V; Simpson M M
Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: contributions of the second membrane-spanning segment.
Biochemistry 1999;38(25):7961-8.
1998: Ferrer J V; Javitch J A
Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9238-43.
1998: Javitch J A; Ballesteros J A; Weinstein H; Chen J
A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice.
Biochemistry 1998;37(4):998-1006.
1998: Javitch J A
Probing structure of neurotransmitter transporters by substituted-cysteine accessibility method.
Methods in enzymology 1998;296():331-46.
1998: Javitch J A
Mapping the binding-site crevice of the D2 receptor.
Advances in pharmacology (San Diego, Calif.) 1998;42():412-5.
1997: Javitch J A; Fu D; Liapakis G; Chen J
Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment.
The Journal of biological chemistry 1997;272(30):18546-9.
1996: Fu D; Ballesteros J A; Weinstein H; Chen J; Javitch J A
Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.
Biochemistry 1996;35(35):11278-85.
1996: Javitch J A; Fu D; Chen J
Differentiating dopamine D2 ligands by their sensitivities to modification of the cysteine exposed in the binding-site crevice.
Molecular pharmacology 1996;49(4):692-8.
1995: Javitch J A; Fu D; Chen J
Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.
Biochemistry 1995;34(50):16433-9.
1995: Javitch J A; Fu D; Chen J; Karlin A
Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method.
Neuron 1995;14(4):825-31.
1994: Javitch J A; Li X; Kaback J; Karlin A
A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10355-9.
1994: Javitch J A; Kaback J; Li X; Karlin A
Expression and characterization of human dopamine D2 receptor in baculovirus-infected insect cells.
Journal of receptor research 1994;14(2):99-117.
1993: Parsons B; Stanley M; Javitch J
Differential visualization of dopamine D2 and D3 receptors in rat brain.
European journal of pharmacology 1993;234(2-3):269-72.
1991: Fallon B A; Javitch J A; Hollander E; Liebowitz M R
Hypochondriasis and obsessive compulsive disorder: overlaps in diagnosis and treatment.
The Journal of clinical psychiatry 1991;52(11):457-60.
1989: Hesdorffer C S; Stoopler M; Javitch J
Aggressive insulinoma with bone metastases.
American journal of clinical oncology 1989;12(6):498-501.

Sign-in to see more