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Donald Jenden

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Oscar Scremin; Mingen Grace Li; Margareth Roch; Ruth Booth; Donald J Jenden
Acetylcholine and choline dynamics provide early and late markers of traumatic brain injury.
Tsung-Ming Shih; Oscar Scremin; Margareth Roch; Ly Huynh; Wei Sun; Donald J Jenden
Cerebral acetylcholine and choline contents and turnover following low-dose acetylcholinesterase inhibitors treatment in rats.
Oscar Scremin; Tsung-Ming Shih; Ly Huynh; Margareth Roch; Wei Sun; Dante Chialvo; Donald J Jenden
Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors.

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All Publications

2006: Oscar Scremin; Mingen Grace Li; Margareth Roch; Ruth Booth; Donald J Jenden
Acetylcholine and choline dynamics provide early and late markers of traumatic brain injury.
Brain research 2006;1124(1):155-66.
2006: Tsung-Ming Shih; Oscar Scremin; Margareth Roch; Ly Huynh; Wei Sun; Donald J Jenden
Cerebral acetylcholine and choline contents and turnover following low-dose acetylcholinesterase inhibitors treatment in rats.
Archives of toxicology 2006;80(11):761-7.
2006: Oscar Scremin; Tsung-Ming Shih; Ly Huynh; Margareth Roch; Wei Sun; Dante Chialvo; Donald J Jenden
Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors.
Journal of applied toxicology : JAT 2006;26(5):410-8.
2006: Alan L Buchman; Marvin E Ament; Donald J Jenden; Chul Ahn
Choline deficiency is associated with increased risk for venous catheter thrombosis.
JPEN. Journal of parenteral and enteral nutrition 2006;30(4):317-20.
2005: Oscar Scremin; Tsung-Ming Shih; Ly Huynh; Margareth Roch; Wei Sun; Dante Chialvo; Donald J Jenden
Low-dose cholinesterase inhibitors do not induce delayed effects on cerebral blood flow and metabolism.
Pharmacology, biochemistry, and behavior 2005;80(4):529-40.
2003: Oscar Scremin; Tsung-Ming Shih; Ly Huynh; Margareth Roch; Ruth Booth; Donald J Jenden
Delayed neurologic and behavioral effects of subtoxic doses of cholinesterase inhibitors.
The Journal of pharmacology and experimental therapeutics 2003;304(3):1111-9.
2001: Alan L Buchman; Marvin E Ament; M Sohel; M Dubin; Donald J Jenden; Margareth Roch; H Pownall; W Farley; M Awal; Chul Ahn
Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial.
JPEN. Journal of parenteral and enteral nutrition 2001;25(5):260-8.
2001: Alan L Buchman; M Sohel; M Brown; Donald J Jenden; Chul Ahn; Margareth Roch; T L Brawley
Verbal and visual memory improve after choline supplementation in long-term total parenteral nutrition: a pilot study.
JPEN. Journal of parenteral and enteral nutrition 2001;25(1):30-5.
2001: Alan L Buchman; M Sohel; A Moukarzel; D Bryant; Richard Schanler; M Awal; P Burns; Karen Dorman; Michael Belfort; Donald J Jenden; Donna Killip; Margareth Roch
Plasma choline in normal newborns, infants, toddlers, and in very-low-birth-weight neonates requiring total parenteral nutrition.
Nutrition (Burbank, Los Angeles County, Calif.) 2001;17(1):18-21.
2000: S Harvey Mudd; Donald J Jenden; Antonieta Capdevila; Margareth Roch; Harvey L Levy; Conrad Wagner
Isolated hypermethioninemia: measurements of S-adenosylmethionine and choline.
Metabolism: clinical and experimental 2000;49(12):1542-7.
2000: Alan L Buchman; M Awal; Donald J Jenden; Margareth Roch; S H Kang
The effect of lecithin supplementation on plasma choline concentrations during a marathon.
Journal of the American College of Nutrition 2000;19(6):768-70.
2000: Alan L Buchman; Donald J Jenden; W N Suki; Margareth Roch
Changes in plasma free and phospholipid-bound choline concentrations in chronic hemodialysis patients.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2000;10(3):133-8.
1999: Alan L Buchman; Donald J Jenden; Margareth Roch
Plasma free, phospholipid-bound and urinary free choline all decrease during a marathon run and may be associated with impaired performance.
Journal of the American College of Nutrition 1999;18(6):598-601.
1999: Sudipta Misra; Chul Ahn; Marvin E Ament; H J Choi; Donald J Jenden; Margareth Roch; Alan L Buchman
Plasma choline concentrations in children requiring long-term home parenteral nutrition: a case control study.
JPEN. Journal of parenteral and enteral nutrition 1999;23(5):305-8.
1998: Oscar Scremin; Tsung-Ming Shih; Mingen Grace Li; Donald J Jenden
Mapping of cerebral metabolic activation in three models of cholinergic convulsions.
Brain research bulletin 1998;45(2):167-74.
1997: Karen H Gylys; I Abdalah; Donald J Jenden
Selectivity of hemicholinium mustard, an affinity ligand, for the high-affinity choline transport system.
Neuropharmacology 1997;36(11-12):1741-6.
1997: Oscar Scremin; Mingen Grace Li; Donald J Jenden
Cholinergic modulation of cerebral cortical blood flow changes induced by trauma.
Journal of neurotrauma 1997;14(8):573-86.
1997: Donald J Jenden
Subtypes of muscarinic receptors: closing summary.
Life sciences 1997;60(13-14):1153-9.
1997: Oscar Scremin; Mingen Grace Li; A M Erika Scremin; Donald J Jenden
Cholinesterase inhibition improves blood flow in the ischemic cerebral cortex.
Brain research bulletin 1997;42(1):59-70.
1996: Linda Chang; Thomas Ernst; Russell Poland; Donald J Jenden
In vivo proton magnetic resonance spectroscopy of the normal aging human brain.
Life sciences 1996;58(22):2049-56.
1996: Oscar Scremin; Donald J Jenden
Cholinergic control of cerebral blood flow in stroke, trauma and aging.
Life sciences 1996;58(22):2011-8.
1996: Donald J Jenden; Oscar Scremin; Margareth Roch; G Li
The influence of aging on whole body choline release and clearance.
Life sciences 1996;58(22):2003-9.
1996: H M Vargas; Donald J Jenden
Elevation of cerebrospinal fluid choline levels by nicotinamide involves the enzymatic formation of N1-methylnicotinamide in brain tissue.
Life sciences 1996;58(22):1995-2002.
1996: Karen H Gylys; Donald J Jenden
Regulation of acetylcholine synthesis in the presence of hemicholinium mustard.
Life sciences 1996;58(22):1937-46.
1996: Bruce L Miller; Linda Chang; R Booth; Thomas Ernst; Marcia E Cornford; D Nikas; D McBride; Donald J Jenden
In vivo 1H MRS choline: correlation with in vitro chemistry/histology.
Life sciences 1996;58(22):1929-35.
1995: Alan L Buchman; M D Dubin; A A Moukarzel; Donald J Jenden; Margareth Roch; K M Rice; J Gornbein; Marvin E Ament
Choline deficiency: a cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation.
Hepatology (Baltimore, Md.) 1995;22(5):1399-403.
1995: Linda Chang; D McBride; Bruce L Miller; Marcia E Cornford; R A Booth; S D Buchthal; T M Ernst; Donald J Jenden
Localized in vivo 1H magnetic resonance spectroscopy and in vitro analyses of heterogeneous brain tumors.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 1995;5(3):157-63.
1995: Donald J Jenden; Oscar Scremin
Effects of hypoxia and hypercapnia on whole body release and clearance of choline.
The American journal of physiology 1995;268(6 Pt 2):R1520-5.
1995: Donald J Jenden
Sixth International Symposium on Subtypes of Muscarinic Receptors. Summary and closing comments.
Life sciences 1995;56(11-12):993-1000.
1994: Alan L Buchman; Donald J Jenden; A A Moukarzel; Margareth Roch; K M Rice; A S Chang; Marvin E Ament
Choline pharmacokinetics during intermittent intravenous choline infusion in human subjects.
Clinical pharmacology and therapeutics 1994;55(3):277-83.
1992: Karen H Gylys; C Mellin; R Amstutz; Donald J Jenden
Characterization of the irreversible inhibition of high-affinity choline transport produced by hemicholinium mustard.
Journal of neurochemistry 1992;59(4):1302-8.
1992: Alan L Buchman; M Dubin; Donald J Jenden; A Moukarzel; Margareth Roch; K Rice; J Gornbein; Marvin E Ament; Curtis D Eckhert
Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients.
Gastroenterology 1992;102(4 Pt 1):1363-70.
1992: R W Russell; R A Booth; Donald J Jenden; A S Chang; K M Rice; Margareth Roch; S D Lauretz
Incomplete reversibility of an experimentally induced hypocholinergic state: biochemical and physiological, but not behavioral, recovery.
Pharmacology, biochemistry, and behavior 1992;41(2):433-44.
1991: Bruce L Miller; S Read; C Tang; Donald J Jenden
Differences in red blood cell choline and lipid-bound choline between patients with Alzheimer disease and control subjects.
Neurobiology of aging 1991;12(1):61-4.
1990: R W Russell; Donald J Jenden; R A Booth; S D Lauretz; K M Rice; Margareth Roch
Global in vivo replacement of choline by N-aminodeanol. Testing a hypothesis about progressive degenerative dementia: II. Physiological and behavioral effects.
Pharmacology, biochemistry, and behavior 1990;37(4):811-20.
1990: B Knusel; Donald J Jenden; S D Lauretz; R A Booth; K M Rice; Margareth Roch; Jerene J Waite
Global in vivo replacement of choline by N-aminodeanol. Testing a hypothesis about progressive degenerative dementia: I. Dynamics of choline replacement.
Pharmacology, biochemistry, and behavior 1990;37(4):799-809.
1990: B Ringdahl; C Mellin; F J Ehlert; Margareth Roch; K M Rice; Donald J Jenden
Tertiary 2-haloethylamine derivatives of the muscarinic agent McN-A-343, [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]trimethylammonium chloride.
Journal of medicinal chemistry 1990;33(1):281-6.
1990: Donald J Jenden
Achievements in cholinergic research, 1969-1989: drug development.
Progress in brain research 1990;84():479-86.
1990: Donald J Jenden; K M Rice; Margareth Roch; R A Booth; S D Lauretz
Effects of nicotinamide on choline and acetylcholine levels in rats.
Advances in neurology 1990;51():131-8.
1989: Bruce L Miller; Donald J Jenden; D Kraemer; C Tang; P Fu
Choline levels in erythrocytes and plasma: a study of species variation.
Biological psychiatry 1989;26(7):741-3.
1989: R W Russell; R A Booth; C A Smith; Donald J Jenden; Margareth Roch; K M Rice; S D Lauretz
Roles of neurotransmitter receptors in behavior: recovery of function following decreases in muscarinic receptor density induced by cholinesterase inhibition.
Behavioral neuroscience 1989;103(4):881-92.
1989: B Ringdahl; E D Katz; Margareth Roch; Donald J Jenden
Muscarinic actions and receptor binding of the enantiomers of BM 130, an alkylating analog of oxotremorine.
The Journal of pharmacology and experimental therapeutics 1989;249(1):210-5.
1989: Jerene J Waite; Donald J Jenden
Spontaneous regeneration of free muscarinic receptor after alkylation by BM 123. II. Recovery in broken cell preparations.
The Journal of pharmacology and experimental therapeutics 1989;248(1):119-26.
1989: Jerene J Waite; Donald J Jenden
Spontaneous regeneration of free muscarinic receptor after alkylation by BM 123. I. Recovery in vivo and in cell culture.
The Journal of pharmacology and experimental therapeutics 1989;248(1):111-8.
1989: Donald J Jenden; R W Russell; R A Booth; B J Knusel; S D Lauretz; K M Rice; Margareth Roch
Effects of chronic in vivo replacement of choline with a false cholinergic precursor.
EXS 1989;57():229-35.
1988: Robert W Silverman; Donald J Jenden
A device to evoke acetylcholine release electrically in the guinea pig myenteric plexus/longitudinal muscle preparation through mass electrodes.
Methods and findings in experimental and clinical pharmacology 1988;10(11):673-6.
1988: David H Overstreet; R A Booth; Donald J Jenden
Effects of an irreversible muscarinic agonist (BM123) on avoidance and spontaneous alternation performance.
Pharmacology, biochemistry, and behavior 1988;31(2):337-43.
1988: B Ringdahl; Margareth Roch; Donald J Jenden
Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists.
Journal of medicinal chemistry 1988;31(1):160-4.
1987: B Ringdahl; Margareth Roch; Donald J Jenden
Regional differences in receptor reserve for analogs of oxotremorine in vivo: implications for development of selective muscarinic agonists.
The Journal of pharmacology and experimental therapeutics 1987;242(2):464-71.
1987: Donald J Jenden; R W Russell; R A Booth; S D Lauretz; B J Knusel; Margareth Roch; K M Rice; R George; Jerene J Waite
A model hypocholinergic syndrome produced by a false choline analog, N-aminodeanol.
Journal of neural transmission. Supplementum 1987;24():325-9.
1986: R W Russell; R A Booth; S D Lauretz; C A Smith; Donald J Jenden
Behavioral, neurochemical and physiological effects of repeated exposures to subsymptomatic levels of the anticholinesterase, soman.
Neurobehavioral toxicology and teratology 1986;8(6):675-85.
1986: R W Russell; C A Smith; R A Booth; Donald J Jenden; Jerene J Waite
Behavioral and physiological effects associated with changes in muscarinic receptors following administration of an irreversible cholinergic agonist (BM 123).
Psychopharmacology 1986;90(3):308-15.
1985: Donald J Jenden; David H Overstreet; R A Booth; R W Russell; K M Rice
Unexpected synergism between an alkylating analog of oxotremorine and soman.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1985;5(6 Pt 2):S78-83.
1985: R Amstutz; B Ringdahl; B Karlén; Margareth Roch; Donald J Jenden
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
Journal of medicinal chemistry 1985;28(12):1760-5.
1985: R W Russell; R A Booth; Donald J Jenden; Margareth Roch; K M Rice
Changes in presynaptic release of acetylcholine during development of tolerance to the anticholinesterase, DFP.
Journal of neurochemistry 1985;45(1):293-9.
1984: B Ringdahl; B Resul; F J Ehlert; Donald J Jenden; R Dahlbom
The conversion of 2-chloroalkylamine analogues of oxotremorine to aziridinium ions and their interactions with muscarinic receptors in the guinea pig ileum.
Molecular pharmacology 1984;26(2):170-9.
1984: F J Ehlert; Donald J Jenden; B Ringdahl
An alkylating derivative of oxotremorine interacts irreversibly with the muscarinic receptor.
Life sciences 1984;34(10):985-91.
1983: B Resul; B Ringdahl; R Dahlbom; Donald J Jenden
Muscarinic activity of some secondary and tertiary amines and quaternary ammonium salts structurally related to oxotremorine.
European journal of pharmacology 1983;87(4):387-96.
1982: B Ringdahl; B Resul; Donald J Jenden; R Dahlbom
Muscarinic activity in the isolated guinea pig ileum of some carboxamides related to oxotremorine.
European journal of pharmacology 1982;85(1):79-83.
1982: R Dahlbom; Donald J Jenden; B Resul; B Ringdahl
Stereochemical requirements for central and peripheral muscarinic and antimuscarinic activity of some acetylenic compounds related to oxotremorine.
British journal of pharmacology 1982;76(2):299-304.