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Christopher Jenkins

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Amino Acid Sequence

Physiology

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Co-Publications
Name
17
Gross, Richard
13
Mancuso, David
8
Han, Xianlin
6
Sims, Harold
5
Yang, Jingyue
4
Yan, Wei
3
Yang, Kui
2
Saffitz, Jeffrey
2
Abendschein, Dana
1
Abumrad, Nada
1
Arner, Peter
1
Bickel, Perry
1
Dicker, Andrea
1
Hoffstedt, Johan
1
Holm, Cecilia

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Publications

TOP 3
Jenkins Christopher M; Cedars Ari; Gross Richard W
Eicosanoid signalling pathways in the heart.
Cedars Ari; Jenkins Christopher M; Mancuso David J; Gross Richard W
Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunction.
Mancuso David J; Sims Harold F; Han Xianlin; Jenkins Christopher M; Guan Shao Ping; Yang Kui; Moon Sung Ho; Pietka Terri; Abumrad Nada A; Schlesinger Paul H; Gross Richard W
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.

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All Publications

2009: Jenkins Christopher M; Cedars Ari; Gross Richard W
Eicosanoid signalling pathways in the heart.
Cardiovascular research 2009;82(2):240-9.
2009: Cedars Ari; Jenkins Christopher M; Mancuso David J; Gross Richard W
Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunction.
Journal of cardiovascular pharmacology 2009;53(4):277-89.
2007: Mancuso David J; Sims Harold F; Han Xianlin; Jenkins Christopher M; Guan Shao Ping; Yang Kui; Moon Sung Ho; Pietka Terri; Abumrad Nada A; Schlesinger Paul H; Gross Richard W
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.
The Journal of biological chemistry 2007;282(48):34611-22.
2007: Mancuso David J; Han Xianlin; Jenkins Christopher M; Lehman John J; Sambandam Nandakumar; Sims Harold F; Yang Jingyue; Yan Wei; Yang Kui; Green Karen; Abendschein Dana R; Saffitz Jeffrey E; Gross Richard W
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
The Journal of biological chemistry 2007;282(12):9216-27.
2006: Jenkins Christopher M; Yan Wei; Mancuso David J; Gross Richard W
Highly selective hydrolysis of fatty acyl-CoAs by calcium-independent phospholipase A2beta. Enzyme autoacylation and acyl-CoA-mediated reversal of calmodulin inhibition of phospholipase A2 activity.
The Journal of biological chemistry 2006;281(23):15615-24.
2005: Langin Dominique; Dicker Andrea; Tavernier Geneviève; Hoffstedt Johan; Mairal Aline; Rydén Mikael; Arner Erik; Sicard Audrey; Jenkins Christopher M; Viguerie Nathalie; van Harmelen Vanessa; Gross Richard W; Holm Cecilia; Arner Peter
Adipocyte lipases and defect of lipolysis in human obesity.
Diabetes 2005;54(11):3190-7.
2005: Yang Jingyue; Gibson Beverly; Snider Jacqueline; Jenkins Christopher M; Han Xianlin; Gross Richard W
Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance.
Biochemistry 2005;44(35):11903-12.
2005: Gross Richard W; Jenkins Christopher M; Yang Jingyue; Mancuso David J; Han Xianlin
Functional lipidomics: the roles of specialized lipids and lipid-protein interactions in modulating neuronal function.
Prostaglandins & other lipid mediators 2005;77(1-4):52-64.
2005: Yan Wei; Jenkins Christopher M; Han Xianlin; Mancuso David J; Sims Harold F; Yang Kui; Gross Richard W
The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling.
The Journal of biological chemistry 2005;280(29):26669-79.
2004: Mancuso David J; Jenkins Christopher M; Sims Harold F; Cohen Joshua M; Yang Jingyue; Gross Richard W
Complex transcriptional and translational regulation of iPLAgamma resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization.
European journal of biochemistry / FEBS 2004;271(23-24):4709-24.
2004: Jenkins Christopher M; Mancuso David J; Yan Wei; Sims Harold F; Gibson Beverly; Gross Richard W
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.
The Journal of biological chemistry 2004;279(47):48968-75.
2004: Su Xiong; Mancuso David J; Bickel Perry E; Jenkins Christopher M; Gross Richard W
Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes.
The Journal of biological chemistry 2004;279(21):21740-8.
2003: Jenkins Christopher M; Han Xianlin; Yang Jingyue; Mancuso David J; Sims Harold F; Muslin Anthony J; Gross Richard W
Purification of recombinant human cPLA2 gamma and identification of C-terminal farnesylation, proteolytic processing, and carboxymethylation by MALDI-TOF-TOF analysis.
Biochemistry 2003;42(40):11798-807.
2003: Mancuso David J; Abendschein Dana R; Jenkins Christopher M; Han Xianlin; Saffitz Jeffrey E; Schuessler Richard B; Gross Richard W
Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition.
The Journal of biological chemistry 2003;278(25):22231-6.
2002: Jenkins Christopher M; Han Xianlin; Mancuso David J; Gross Richard W
Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.
The Journal of biological chemistry 2002;277(36):32807-14.
2001: Jenkins C M; Wolf M J; Mancuso D J; Gross R W
Identification of the calmodulin-binding domain of recombinant calcium-independent phospholipase A2beta. implications for structure and function.
The Journal of biological chemistry 2001;276(10):7129-35.
2000: Mancuso D J; Jenkins C M; Gross R W
The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2).
The Journal of biological chemistry 2000;275(14):9937-45.

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