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Donald Jenkinson

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David I Fletcher; C Robin Ganellin; Alessandro Piergentili; Philip M Dunn; Donald H Jenkinson
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
Donald H Jenkinson
Potassium channels--multiplicity and challenges.
C J Roxburgh; C Robin Ganellin; S Athmani; A Bisi; W Quaglia; David C H Benton; M A Shiner; Misbah Malik-Hall; Dennis G Haylett; Donald H Jenkinson
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca(2+)-activated K+ permeability of erythrocytes.

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All Publications

2007: David I Fletcher; C Robin Ganellin; Alessandro Piergentili; Philip M Dunn; Donald H Jenkinson
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
Bioorganic & medicinal chemistry 2007;15(16):5457-79.
2006: Donald H Jenkinson
Potassium channels--multiplicity and challenges.
British journal of pharmacology 2006;147 Suppl 1():S63-71.
2001: C J Roxburgh; C Robin Ganellin; S Athmani; A Bisi; W Quaglia; David C H Benton; M A Shiner; Misbah Malik-Hall; Dennis G Haylett; Donald H Jenkinson
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca(2+)-activated K+ permeability of erythrocytes.
Journal of medicinal chemistry 2001;44(20):3244-53.
2001: Ramine Hosseini; David C H Benton; Philip M Dunn; Donald H Jenkinson; Guy W J Moss
SK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neurones.
The Journal of physiology 2001;535(Pt 2):323-34.
2000: J Q Chen; Dimitrios Galanakis; C Robin Ganellin; Philip M Dunn; Donald H Jenkinson
bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel.
Journal of medicinal chemistry 2000;43(19):3478-81.
2000: Misbah Malik-Hall; C Robin Ganellin; Dimitrios Galanakis; Donald H Jenkinson
Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channels.
British journal of pharmacology 2000;129(7):1431-8.
2000: J Campos Rosa; Dimitrios Galanakis; Alessandro Piergentili; K Bhandari; C Robin Ganellin; Philip M Dunn; Donald H Jenkinson
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca(2+)-activated K(+) channel.
Journal of medicinal chemistry 2000;43(3):420-31.
1999: David C H Benton; C J Roxburgh; C Robin Ganellin; M A Shiner; Donald H Jenkinson
Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells.
British journal of pharmacology 1999;126(1):169-78.
1998: J C Rosa; Dimitrios Galanakis; C Robin Ganellin; Philip M Dunn; Donald H Jenkinson
Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.
Journal of medicinal chemistry 1998;41(1):2-5.
1996: Dimitrios Galanakis; C Robin Ganellin; Philip M Dunn; Donald H Jenkinson
On the concept of a bivalent pharmacophore for SKCa channel blockers: synthesis, pharmacological testing, and radioligand binding studies on mono-, bis-, and tris-quinolinium compounds.
Archiv der Pharmazie 1996;329(12):524-8.
1996: C J Roxburgh; C Robin Ganellin; M A Shiner; D C Benton; Philip M Dunn; Y Ayalew; Donald H Jenkinson
The synthesis and some pharmacological actions of the enantiomers of the K(+)-channel blocker cetiedil.
The Journal of pharmacy and pharmacology 1996;48(8):851-7.
1996: Philip M Dunn; D C Benton; J Campos Rosa; C Robin Ganellin; Donald H Jenkinson
Discrimination between subtypes of apamin-sensitive Ca(2+)-activated K+ channels by gallamine and a novel bis-quaternary quinolinium cyclophane, UCL 1530.
British journal of pharmacology 1996;117(1):35-42.
1995: Dimitrios Galanakis; C A Davis; B Del Rey Herrero; C Robin Ganellin; Philip M Dunn; Donald H Jenkinson
Synthesis and structure-activity relationships of dequalinium analogues as K+ channel blockers. Investigations on the role of the charged heterocycle.
Journal of medicinal chemistry 1995;38(4):595-606.
1993: N A Castle; D G Haylett; J M Morgan; Donald H Jenkinson
Dequalinium: a potent inhibitor of apamin-sensitive K+ channels in hepatocytes and of nicotinic responses in skeletal muscle.
European journal of pharmacology 1993;236(2):201-7.
1992: C A Sandford; J H Sweiry; Donald H Jenkinson
Properties of a cell volume-sensitive potassium conductance in isolated guinea-pig and rat hepatocytes.
The Journal of physiology 1992;447():133-48.
1989: N A Castle; D G Haylett; Donald H Jenkinson
Toxins in the characterization of potassium channels.
Trends in neurosciences 1989;12(2):59-65.
1987: A C Field; Donald H Jenkinson
The effect of noradrenaline on the ion permeability of isolated mammalian hepatocytes, studied by intracellular recording.
The Journal of physiology 1987;392():493-512.
1985: P R Gater; D G Haylett; Donald H Jenkinson
Neuromuscular blocking agents inhibit receptor-mediated increases in the potassium permeability of intestinal smooth muscle.
British journal of pharmacology 1985;86(4):861-8.
1983: Donald H Jenkinson; D G Haylett; N S Cook
Calcium-activated potassium channels in liver cells.
Cell calcium 1983;4(5-6):429-37.