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Eric Jenkinson

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Jennifer E Cowan; Eric J Jenkinson; William E Jenkinson; Peter J L Lane; Kyoko Nakamura; Sonia M Parnell; Jorge H Caamano; Graham Anderson
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
Song Baik; Eric J Jenkinson; Graham Anderson; Peter J L Lane; William E Jenkinson
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors.
Guillaume E Desanti; Eric J Jenkinson; William E Jenkinson; Peter J L Lane; Sonia M Parnell; Josef M Penninger; Andrea J White; Song Baik; Jennifer E Cowan; Graham Anderson
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.

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All Publications

2013: Jennifer E Cowan; Eric J Jenkinson; William E Jenkinson; Peter J L Lane; Kyoko Nakamura; Sonia M Parnell; Jorge H Caamano; Graham Anderson
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
The Journal of experimental medicine 2013;210(4):675-81.
2013: Song Baik; Eric J Jenkinson; Graham Anderson; Peter J L Lane; William E Jenkinson
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors.
European journal of immunology 2013;43(3):589-94.
2012: Guillaume E Desanti; Eric J Jenkinson; William E Jenkinson; Peter J L Lane; Sonia M Parnell; Josef M Penninger; Andrea J White; Song Baik; Jennifer E Cowan; Graham Anderson
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(12):5519-26.
2012: Natalie A Roberts; Anna Katharina Simon; Yousuke Takahama; Gleb Turchinovich; Andrea J White; David R Withers; Cecile Benezech; Jorge H Caamano; Adam F Cunningham; Guillaume E Desanti; Adrian C Hayday; Eric J Jenkinson; William E Jenkinson; Peter J L Lane; Fiona M McConnell; Kyoko Nakamura; Takeshi Nitta; Izumi Ohigashi; Magdalena Paolino; Sonia M Parnell; Josef M Penninger; Graham Anderson
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Immunity 2012;36(3):427-37.
2012: William E Jenkinson; Kyoko Nakamura; Andrea J White; Eric J Jenkinson; Graham Anderson
Normal T cell selection occurs in CD205-deficient thymic microenvironments.
PloS one 2012;7(12):e53416.
2011: Zoltan Varecza; Krisztian Kvell; Gergely Talabér; Gyorgy Miskei; Veronika Csongei; Domokos Bartis; Graham Anderson; Eric J Jenkinson; Judit Pongracz
Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence.
Mechanisms of ageing and development 2011;132(5):249-56.
2011: Guillaume E Desanti; William E Jenkinson; Sonia M Parnell; Amine Boudil; Laetitia Gautreau-Rolland; Bertus Eksteen; Sophie Ezine; Peter J L Lane; Eric J Jenkinson; Graham Anderson
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(9):5227-35.
2010: Andrea J White; Kyoko Nakamura; William E Jenkinson; Manoj Saini; Charles Sinclair; Benedict Seddon; Parth Narendran; Klaus Pfeffer; Takeshi Nitta; Yousuke Takahama; Jorge H Caamano; Peter J L Lane; Eric J Jenkinson; Graham Anderson
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(8):4769-76.
2009: Natalie A Roberts; Guillaume E Desanti; David Withers; Hamish R Scott; William E Jenkinson; Peter J L Lane; Eric J Jenkinson; Graham Anderson
Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult.
European journal of immunology 2009;39(9):2395-402.
2009: Graham Anderson; Eric J Jenkinson; Hans-Reimer Rodewald
A roadmap for thymic epithelial cell development.
European journal of immunology 2009;39(7):1694-9.
2009: Saba Shakib; Guillaume E Desanti; William E Jenkinson; Sonia M Parnell; Eric J Jenkinson; Graham Anderson
Checkpoints in the development of thymic cortical epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):130-7.
2009: Stephanie H Glanville; Vasilios Bekiaris; Eric J Jenkinson; Peter J L Lane; Graham Anderson; David Withers
Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization.
European journal of immunology 2009;39(1):280-9.
2008: William E Jenkinson; Andrea Bacon; Andrea J White; Graham Anderson; Eric J Jenkinson
An epithelial progenitor pool regulates thymus growth.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6101-8.
2008: Mi-Yeon Kim; Simona Rossi; David Withers; Fiona M McConnell; Kai-Michael Toellner; Fabrina M C Gaspal; Eric J Jenkinson; Graham Anderson; Peter J L Lane
Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues.
Immunology 2008;124(2):166-74.
2008: Andrea J White; David Withers; Sonia M Parnell; Hamish Scott; Daniela Finke; Peter J L Lane; Eric J Jenkinson; Graham Anderson
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
European journal of immunology 2008;38(4):942-7.
2008: Brian J Ferguson; Clare Alexander; Simona Rossi; Ingrid Liiv; Ana Rebane; Catherine L Worth; Joyce Wong; Martti Laan; Pärt Peterson; Eric J Jenkinson; Graham Anderson; Hamish Scott; Anne Cooke; Tina Rich
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.
The Journal of biological chemistry 2008;283(3):1723-31.
2008: Andrea White; Eric J Jenkinson; Graham Anderson
Reaggregate thymus cultures.
Journal of visualized experiments : JoVE 2008;(18):.
2008: William E Jenkinson; Eric J Jenkinson; Graham Anderson
Preparation of 2-dGuo-treated thymus organ cultures.
Journal of visualized experiments : JoVE 2008;(18):.
2007: Vasilios Bekiaris; David Withers; Stephanie H Glanville; Fiona M McConnell; Sonia M Parnell; Mi-Yeon Kim; Fabrina M C Gaspal; Eric J Jenkinson; Clive Sweet; Graham Anderson; Peter J L Lane
Role of CD30 in B/T segregation in the spleen.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7535-43.
2007: Graham Anderson; Peter J L Lane; Eric J Jenkinson
Generating intrathymic microenvironments to establish T-cell tolerance.
Nature reviews. Immunology 2007;7(12):954-63.
2007: Andrea White; Damian Carragher; Sonia M Parnell; Aichi Msaki; Neil Perkins; Peter Lane; Eric J Jenkinson; Graham Anderson; Jorge Caamaño
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.
Blood 2007;110(6):1950-9.
2007: Simona Rossi; Ann P Chidgey; Sonia M Parnell; William E Jenkinson; Hamish Scott; Richard L Boyd; Eric J Jenkinson; Graham Anderson
Redefining epithelial progenitor potential in the developing thymus.
European journal of immunology 2007;37(9):2411-8.
2007: William E Jenkinson; Simona Rossi; Sonia M Parnell; William W Agace; Yousuke Takahama; Eric J Jenkinson; Graham Anderson
Chemokine receptor expression defines heterogeneity in the earliest thymic migrants.
European journal of immunology 2007;37(8):2090-6.
2007: Siân Lax; Tie Zheng Hou; Eric J Jenkinson; Mike Salmon; John R MacFadyen; Clare M Isacke; Graham Anderson; Adam F Cunningham; Christopher D Buckley
CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair.
FEBS letters 2007;581(18):3550-6.
2007: Simona Rossi; Mi-Yeon Kim; Andreas Leibbrandt; Sonia M Parnell; William E Jenkinson; Stephanie H Glanville; Fiona M McConnell; Hamish Scott; Josef M Penninger; Eric J Jenkinson; Peter J L Lane; Graham Anderson
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.
The Journal of experimental medicine 2007;204(6):1267-72.
2007: Mi-Yeon Kim; Fiona M McConnell; Fabrina M C Gaspal; Andrea White; Stephanie H Glanville; Vasilios Bekiaris; Lucy S K Walker; Jorge Caamano; Eric J Jenkinson; Graham Anderson; Peter J L Lane
Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen.
Blood 2007;109(4):1602-10.
2007: William E Jenkinson; Simona Rossi; Sonia M Parnell; Eric J Jenkinson; Graham Anderson
PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches.
Blood 2007;109(3):954-60.
2007: Graham Anderson; Eric J Jenkinson
Fetal thymus organ culture.
CSH protocols 2007;2007():pdb.prot4808.
2006: Mi-Yeon Kim; Kai-Michael Toellner; Andrea White; Fiona M McConnell; Fabrina M C Gaspal; Sonia M Parnell; Eric J Jenkinson; Graham Anderson; Peter J L Lane
Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15).
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3074-81.
2006: Judit Pongracz; Sonia M Parnell; Terry Jones; Graham Anderson; Eric J Jenkinson
Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development.
European journal of immunology 2006;36(9):2376-83.
2006: Eric J Jenkinson; William E Jenkinson; Simona Rossi; Graham Anderson
The thymus and T-cell commitment: the right niche for Notch?
Nature reviews. Immunology 2006;6(7):551-5.
2006: Simona Rossi; William E Jenkinson; Graham Anderson; Eric J Jenkinson
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium.
Nature 2006;441(7096):988-91.
2006: Graham Anderson; William E Jenkinson; Terry Jones; Sonia M Parnell; Francesca A M Kinsella; Andrea J White; Judit E Pongrac'z; Simona Rossi; Eric J Jenkinson
Establishment and functioning of intrathymic microenvironments.
Immunological reviews 2006;209():10-27.
2005: William E Jenkinson; Simona Rossi; Eric J Jenkinson; Graham Anderson
Development of functional thymic epithelial cells occurs independently of lymphostromal interactions.
Mechanisms of development 2005;122(12):1294-9.
2005: Benjamin C Harman; William E Jenkinson; Sonia M Parnell; Simona Rossi; Eric J Jenkinson; Graham Anderson
T/B lineage choice occurs prior to intrathymic Notch signaling.
Blood 2005;106(3):886-92.
2005: Mi-Yeon Kim; Graham Anderson; Andrea White; Eric J Jenkinson; Wiebke Arlt; Inga-Lill Martensson; Lena Erlandsson; Peter J L Lane
OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6686-91.
2004: Damian Carragher; Ramneek Johal; Adele Button; Andrea White; Aristides G Eliopoulos; Eric J Jenkinson; Graham Anderson; Jorge Caamaño
A stroma-derived defect in NF-kappaB2-/- mice causes impaired lymph node development and lymphocyte recruitment.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2271-9.
2003: Katherine J Hare; Judit Pongracz; Eric J Jenkinson; Graham Anderson
Modeling TCR signaling complex formation in positive selection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2825-31.
2003: Nikla R Emambokus; Alexandros Vegiopoulos; Ben Harman; Eric J Jenkinson; Graham Anderson; Jon Frampton
Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.
The EMBO journal 2003;22(17):4478-88.
2003: William E Jenkinson; Eric J Jenkinson; Graham Anderson
Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.
The Journal of experimental medicine 2003;198(2):325-32.
2003: Angela Denzel; Katherine J Hare; Chao Zhang; Kevan M Shokat; Eric J Jenkinson; Graham Anderson; Adrian C Hayday
Cutting edge: a chemical genetic system for the analysis of kinases regulating T cell development.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):519-23.
2003: Judit Pongracz; Katherine J Hare; Benjamin C Harman; Graham Anderson; Eric J Jenkinson
Thymic epithelial cells provide WNT signals to developing thymocytes.
European journal of immunology 2003;33(7):1949-56.
2003: Judit Pongracz; Sonia M Parnell; Graham Anderson; Jean-Pierre Jaffrézou; Eric J Jenkinson
Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes.
Molecular immunology 2003;39(16):1013-23.
2003: Benjamin C Harman; Eric J Jenkinson; Graham Anderson
Microenvironmental regulation of Notch signalling in T cell development.
Seminars in immunology 2003;15(2):91-7.
2003: Benjamin C Harman; Eric J Jenkinson; Graham Anderson
Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1299-303.
2002: Katherine J Hare; Judit Pongracz; Eric J Jenkinson; Graham Anderson
Induction of thymocyte positive selection does not convey immediate resistance to negative selection.
Immunology 2002;105(2):163-70.
2001: Graham Anderson; Judit Pongracz; Sonia M Parnell; Eric J Jenkinson
Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling.
European journal of immunology 2001;31(11):3349-54.
2001: Graham Anderson; Eric J Jenkinson
Lymphostromal interactions in thymic development and function.
Nature reviews. Immunology 2001;1(1):31-40.
2001: Helen Travers; Graham Anderson; Dean Gentle; Eric J Jenkinson; John Girdlestone
Protocols for high efficiency, stage-specific retroviral transduction of murine fetal thymocytes and thymic epithelial cells.
Journal of immunological methods 2001;253(1-2):209-22.
2001: Katherine J Hare; Eric J Jenkinson; Graham Anderson
Specialisation of thymic epithelial cells for positive selection of CD4+8+ thymocytes.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(1):119-27.
2000: Graham Anderson; Benjamin C Harman; Katherine J Hare; Eric J Jenkinson
Microenvironmental regulation of T cell development in the thymus.
Seminars in immunology 2000;12(5):457-64.
2000: Katherine J Hare; Eric J Jenkinson; Graham Anderson
An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2410-4.
2000: Claire M Banwell; KM Partington; Eric J Jenkinson; Graham Anderson
Studies on the role of IL-7 presentation by mesenchymal fibroblasts during early thymocyte development.
European journal of immunology 2000;30(8):2125-9.
2000: Graham Anderson; Eric J Jenkinson
Review article: thymus organ cultures and T-cell receptor repertoire development.
Immunology 2000;100(4):405-10.
2000: RK Suniara; Eric J Jenkinson; JJ Owen
An essential role for thymic mesenchyme in early T cell development.
The Journal of experimental medicine 2000;191(6):1051-6.
2000: JJ Owen; DE McLoughlin; RK Suniara; Eric J Jenkinson
The role of mesenchyme in thymus development.
Current topics in microbiology and immunology 2000;251():133-7.
1999: Eric J Jenkinson; Sonia M Parnell; John Shuttleworth; JJ Owen; Graham Anderson
Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):5781-5.
1999: G M Poirier; G Anderson; A Huvar; P C Wagaman; J Shuttleworth; Eric J Jenkinson; MR Jackson; PA Peterson; Mark G Erlander
Immune-associated nucleotide-1 (IAN-1) is a thymic selection marker and defines a novel gene family conserved in plants.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4960-9.
1999: Graham Anderson; Katherine J Hare; Eric J Jenkinson
Positive selection of thymocytes: the long and winding road.
Immunology today 1999;20(10):463-8.
1999: JJ Owen; DE McLoughlin; RK Suniara; Eric J Jenkinson
Cellular and matrix interactions during the development of T lymphocytes.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(5):551-5.
1999: Katherine J Hare; Eric J Jenkinson; Graham Anderson
CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):3978-83.
1999: B Wilkinson; JJ Owen; Eric J Jenkinson
Factors regulating stem cell recruitment to the fetal thymus.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):3873-81.
1999: KM Partington; Eric J Jenkinson; Graham Anderson
A novel method of cell separation based on dual parameter immunomagnetic cell selection.
Journal of immunological methods 1999;223(2):195-205.
1999: Katherine J Hare; Eric J Jenkinson; Graham Anderson
In vitro models of T cell development.
Seminars in immunology 1999;11(1):3-12.
1999: RK Suniara; Eric J Jenkinson; JJ Owen
Studies on the phenotype of migrant thymic stem cells.
European journal of immunology 1999;29(1):75-80.
1998: Graham Anderson; KM Partington; Eric J Jenkinson
Differential effects of peptide diversity and stromal cell type in positive and negative selection in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6599-603.
1998: Graham Anderson; Eric J Jenkinson
Use of explant technology in the study of in vitro immune responses.
Journal of immunological methods 1998;216(1-2):155-63.
1998: KL Anderson; N C Moore; DE McLoughlin; Eric J Jenkinson; JJ Owen
Studies on thymic epithelial cells in vitro.
Developmental and comparative immunology 1998;22(3):367-77.
1998: Katherine J Hare; R W Wilkinson; Eric J Jenkinson; Graham Anderson
Identification of a developmentally regulated phase of postselection expansion driven by thymic epithelium.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3666-72.
1998: H E Porritt; KL Anderson; RK Suniara; Eric J Jenkinson; JJ Owen
Cellular interactions in the thymus regulate the protein kinase C signaling pathway.
European journal of immunology 1998;28(4):1197-203.
1997: E Z Tchilian; JJ Owen; Eric J Jenkinson
Anti-alpha 4 integrin antibody induces apoptosis in murine thymocytes and staphylococcal enterotoxin B-activated lymph node T cells.
Immunology 1997;92(3):321-7.
1997: Graham Anderson; Katherine J Hare; N Platt; Eric J Jenkinson
Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection.
European journal of immunology 1997;27(8):1838-42.
1997: Graham Anderson; Eric J Jenkinson
Piecing together the thymic puzzle.
Immunology today 1997;18(8):363-4.
1997: Graham Anderson; KL Anderson; E Z Tchilian; JJ Owen; Eric J Jenkinson
Fibroblast dependency during early thymocyte development maps to the CD25+ CD44+ stage and involves interactions with fibroblast matrix molecules.
European journal of immunology 1997;27(5):1200-6.
1996: K L Anderson; Graham Anderson; Robert H Michell; Eric J Jenkinson; JJ Owen
Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4083-91.
1996: E Z Tchilian; Graham Anderson; N C Moore; JJ Owen; Eric J Jenkinson
Involvement of LFA-1/ICAM-2 adhesive interactions and PKC in activation-induced cell death following SEB rechallenge.
Immunology 1996;87(4):566-72.
1996: G Anderson; N C Moore; JJ Owen; Eric J Jenkinson
Cellular interactions in thymocyte development.
Annual review of immunology 1996;14():73-99.
1995: R W Wilkinson; Graham Anderson; JJ Owen; Eric J Jenkinson
Positive selection of thymocytes involves sustained interactions with the thymic microenvironment.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5234-40.
1995: N C Moore; John Girdlestone; Graham Anderson; JJ Owen; Eric J Jenkinson
Stimulation of thymocytes before and after positive selection results in the induction of different NF-kappa B/Rel protein complexes.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4653-60.
1995: L A Conroy; Eric J Jenkinson; JJ Owen; Robert H Michell
Phosphatidylinositol 4,5-bisphosphate hydrolysis accompanies T cell receptor-induced apoptosis of murine thymocytes within the thymus.
European journal of immunology 1995;25(7):1828-35.
1995: Graham Anderson; Eric J Jenkinson
The role of the thymus during T-lymphocyte development in vitro.
Seminars in immunology 1995;7(3):177-83.
1995: Graham Anderson; K L Anderson; L A Conroy; T J Hallam; N C Moore; JJ Owen; Eric J Jenkinson
Intracellular signaling events during positive and negative selection of CD4+CD8+ thymocytes in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3636-43.
1994: A R Ready; Eric J Jenkinson
The role of macrophages and bone marrow-derived dendritic cells in the rejection of fetal thymus allografts.
Immunology 1994;83(3):465-8.
1994: Graham Anderson; JJ Owen; N C Moore; Eric J Jenkinson
Characteristics of an in vitro system of thymocyte positive selection.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(5):1915-20.
1994: Graham Anderson; JJ Owen; N C Moore; Eric J Jenkinson
Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro.
The Journal of experimental medicine 1994;179(6):2027-31.
1994: N C Moore; Graham Anderson; D E McLoughlin; JJ Owen; Eric J Jenkinson
Differential expression of Mtv loci in MHC class II-positive thymic stromal cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(10):4826-31.
1994: N C Moore; Graham Anderson; G T Williams; JJ Owen; Eric J Jenkinson
Developmental regulation of bcl-2 expression in the thymus.
Immunology 1994;81(1):115-9.
1994: Eric J Jenkinson; G Anderson; N C Moore; C A Smith; JJ Owen
Positive selection by purified MHC class II+ thymic epithelial cells in vitro: costimulatory signals mediated by B7 are not involved.
Developmental immunology 1994;3(4):265-71.
1993: N C Moore; Graham Anderson; C A Smith; JJ Owen; Eric J Jenkinson
Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction.
European journal of immunology 1993;23(4):922-7.
1993: Graham Anderson; Eric J Jenkinson; N C Moore; JJ Owen
MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus.
Nature 1993;362(6415):70-3.
1992: N C Moore; Eric J Jenkinson; JJ Owen
Effects of the thymic microenvironment on the response of thymocytes to stimulation.
European journal of immunology 1992;22(10):2533-7.
1992: Eric J Jenkinson; Graham Anderson; JJ Owen
Studies on T cell maturation on defined thymic stromal cell populations in vitro.
The Journal of experimental medicine 1992;176(3):845-53.
1992: Robert H Michell; L A Conroy; M Finney; P J French; Christopher M Bunce; K Anderson; M A Baxter; Geoffrey Brown; John Gordon; Eric J Jenkinson
Inositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells.
Ciba Foundation symposium 1992;164():2-11; discussion 12-6.
1991: L A Conroy; Eric J Jenkinson; JJ Owen; Robert H Michell
The role of inositol lipid hydrolysis in the selection of immature thymocytes.
Biochemical Society transactions 1991;19(2):90S.
1990: Eric J Jenkinson; R Kingston; JJ Owen
Newly generated thymocytes are not refractory to deletion when the alpha/beta component of the T cell receptor is engaged by the superantigen staphylococcal enterotoxin B.
European journal of immunology 1990;20(11):2517-20.
1990: A Murdoch; Eric J Jenkinson; G D Johnson; J J Owen
Alkaline phosphatase-fast red, a new fluorescent label. Application in double labelling for cell cycle analysis.
Journal of immunological methods 1990;132(1):45-9.
1990: Simon R Carding; S Kyes; Eric J Jenkinson; R Kingston; Kim Bottomly; J J Owen; Adrian C Hayday
Developmentally regulated fetal thymic and extrathymic T-cell receptor gamma delta gene expression.
Genes & development 1990;4(8):1304-15.
1990: JJ Owen; Eric J Jenkinson; R Kingston; G T Williams; C A Smith
Cell growth and gene rearrangement signals during the development of T lymphocytes within the thymus.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1990;327(1239):111-6.
1990: Eric J Jenkinson; J J Owen
T-cell differentiation in thymus organ cultures.
Seminars in immunology 1990;2(1):51-8.
1989: Eric J Jenkinson; R Kingston; C A Smith; G T Williams; JJ Owen
Antigen-induced apoptosis in developing T cells: a mechanism for negative selection of the T cell receptor repertoire.
European journal of immunology 1989;19(11):2175-7.
1989: Bruno Kyewski; Eric J Jenkinson; R Kingston; Peter Altevogt; M J Owen; JJ Owen
The effects of anti-CD2 antibodies on the differentiation of mouse thymocytes.
European journal of immunology 1989;19(5):951-4.
1989: Simon R Carding; Eric J Jenkinson; R Kingston; Adrian C Hayday; Kim Bottomly; J J Owen
Developmental control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3342-5.
1989: C A Smith; G T Williams; R Kingston; Eric J Jenkinson; JJ Owen
Apoptosis.
Nature 1989;338(6210):10.
1989: C A Smith; G T Williams; R Kingston; Eric J Jenkinson; JJ Owen
Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures.
Nature 1989;337(6203):181-4.
1988: I G Parkin; JJ Owen; Eric J Jenkinson
Proliferation of thymocytes in relation to T-cell receptor beta-chain expression.
Immunology 1988;64(1):97-9.
1988: JJ Owen; M J Owen; G T Williams; R Kingston; Eric J Jenkinson
The effects of anti-CD3 antibodies on the development of T-cell receptor alpha beta + lymphocytes in embryonic thymus organ cultures.
Immunology 1988;63(4):639-42.
1988: G Buckley; M T Benson; Eric J Jenkinson; JJ Owen
Factors affecting the acceptance of deoxyguanosine-treated thymus allografts.
Transplantation 1988;45(1):202-5.
1987: A R Ready; Eric J Jenkinson
Deoxyguanosine-induced survival of class II-expressing fetal mouse thymic allografts is associated with the depletion of donor lymphoid and dendritic cells.
Transplantation proceedings 1987;19(5):4225-6.
1987: Eric J Jenkinson; R Kingston; JJ Owen
Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors.
Nature 1987;329(6135):160-2.
1986: G T Williams; R Kingston; M J Owen; Eric J Jenkinson; JJ Owen
A single micromanipulated stem cell gives rise to multiple T-cell receptor gene rearrangements in the thymus in vitro.
Nature 1986;324(6092):63-4.
1986: JJ Owen; R Kingston; Eric J Jenkinson
Generation of cells expressing cytoplasmic and/or surface T-cell receptor beta chains during the development of mouse fetal thymus.
Immunology 1986;59(1):23-7.
1986: M J Owen; Eric J Jenkinson; G T Williams; R Kingston; JJ Owen
An investigation of T cell receptor gene rearrangement and expression in organ cultures of normal embryonic thymus and Thy-1+ cells of nude mice.
European journal of immunology 1986;16(7):875-8.
1985: R Kingston; Eric J Jenkinson; JJ Owen
A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations.
Nature 1985;317(6040):811-3.
1985: E Van Vliet; Eric J Jenkinson; R Kingston; JJ Owen; W Van Ewijk
Stromal cell types in the developing thymus of the normal and nude mouse embryo.
European journal of immunology 1985;15(7):675-81.
1985: Eric J Jenkinson; P Jhittay; R Kingston; JJ Owen
Studies of the role of the thymic environment in the induction of tolerance to MHC antigens.
Transplantation 1985;39(3):331-3.
1985: Eric J Jenkinson; R Kingston; JJ Owen
Stromal cell populations in the developing thymus of normal and nude mice.
Advances in experimental medicine and biology 1985;186():245-9.
1984: R Kingston; Eric J Jenkinson; JJ Owen
Characterization of stromal cell populations in the developing thymus of normal and nude mice.
European journal of immunology 1984;14(11):1052-6.
1984: A R Ready; Eric J Jenkinson; R Kingston; JJ Owen
Successful transplantation across major histocompatibility barrier of deoxyguanosine-treated embryonic thymus expressing class II antigens.
Nature 1984;310(5974):231-3.
1982: Eric J Jenkinson; L L Franchi; R Kingston; JJ Owen
Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: application in the production of chimeric thymus rudiments.
European journal of immunology 1982;12(7):583-7.