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Guido Jenster

Research Profile

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Publications

TOP 3
Joost L Boormans; Carola V de Vos; Guido Jenster; Hanneke Korsten; Geert J L H van Leenders; Angelique J C Ziel-van der Made; Jan Trapman
Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer.
Olivia Larne; Giuseppe Lippolis; Elena Martens-Uzunova; Anders Bjartell; Mirella S Vredenbregt-van den Berg; Anders Edsjö; Zandra Hagman; Guido Jenster; Yvonne Ceder
miQ-A novel microRNA based diagnostic and prognostic tool for prostate cancer.
Inês Teles Alves; Jan Trapman; Peter van der Spek; Thomas Hartjes; Saskia Hiltemann; Andrew Stubbs; Guido Jenster
Gene fusions by chromothripsis of chromosome 5q in the VCaP prostate cancer cell line.

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All Publications

2013: Joost L Boormans; Carola V de Vos; Guido Jenster; Hanneke Korsten; Geert J L H van Leenders; Angelique J C Ziel-van der Made; Jan Trapman
Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer.
International journal of cancer. Journal international du cancer 2013;133(2):335-45.
2013: Olivia Larne; Giuseppe Lippolis; Elena Martens-Uzunova; Anders Bjartell; Mirella S Vredenbregt-van den Berg; Anders Edsjö; Zandra Hagman; Guido Jenster; Yvonne Ceder
miQ-A novel microRNA based diagnostic and prognostic tool for prostate cancer.
International journal of cancer. Journal international du cancer 2013;132(12):2867-75.
2013: Inês Teles Alves; Jan Trapman; Peter van der Spek; Thomas Hartjes; Saskia Hiltemann; Andrew Stubbs; Guido Jenster
Gene fusions by chromothripsis of chromosome 5q in the VCaP prostate cancer cell line.
Human genetics 2013;132(6):709-13.
2013: Chris H Bangma; Lara Bellardita; Meelan Bul; Peter R Carroll; Louis J Denis; Mark Emberton; Caroline M Hoeks; Guido Jenster; Yoshiyuki Kakehi; Michael W Kattan; Laurence H Klotz; Ida J Korfage; Janet A Lane; Chris Parker; Tom Pickles; Antti Rannikko; Monique J Roobol; Fritz H Schröder; Axel Semjonow; Ewout W Steyerberg; Bruce J Trock; Theo H van der Kwast; Riccardo Valdagni
Active surveillance for low-risk prostate cancer.
Critical reviews in oncology/hematology 2013;85(3):295-302.
2012: Jan Hofland; Guido Jenster; Jacobie Steenbergen; Wytske M Van Weerden; Natasja Dits; Frank H de Jong
Activin A stimulates AKR1C3 expression and growth in human prostate cancer.
Endocrinology 2012;153(12):5726-34.
2012: Dennis J van de Wijngaart; Martin E van Royen; Hendrikus J Dubbink; Jan Trapman; Guido Jenster
Androgen receptor coregulators: recruitment via the coactivator binding groove.
Molecular and cellular endocrinology 2012;352(1-2):57-69.
2012: A Marije Hoogland; Guido Jenster; Monique J Roobol; Fritz H Schröder; Jan Trapman; Theo Van der Kwast; Wytske M Van Weerden; Mark F Wildhagen; Geert J L H van Leenders
ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012;25(3):471-9.
2012: E S Martens-Uzunova; S Møller; J Trapman; Geert J L H van Leenders; T Visakorpi; C H Bangma; Natasja Dits; S E Jalava; T Litman; Guido Jenster
Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer.
Oncogene 2012;31(8):978-91.
2012: Flip H Jansen; Chris H Bangma; Suzanne Reneman; Monique J Roobol; Frank J T Staal; Wilma Teubel; Gert-Jan C M van den Bemd; Angelique L C T van Rijswijk; Wytske M Van Weerden; Guido Jenster
Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers.
Journal of proteome research 2012;11(2):728-35.
2011: Kati P Porkka; Erinn-Lee Ogg; Outi Saramäki; Robert L Vessella; Heidi Pukkila; Harri Lähdesmäki; Wytske M Van Weerden; Maija Wolf; Olli P Kallioniemi; Guido Jenster; Tapio Visakorpi
The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers.
Genes, chromosomes & cancer 2011;50(7):499-509.
2011: Diederick Duijvesz; Theo M Luider; Chris H Bangma; Guido Jenster
Exosomes as biomarker treasure chests for prostate cancer.
European urology 2011;59(5):823-31.
2011: Kati K Waltering; Kati P Porkka; Sanni E Jalava; Alfonso Urbanucci; Pekka J Kohonen; Leena M Latonen; Olli P Kallioniemi; Guido Jenster; Tapio Visakorpi
Androgen regulation of micro-RNAs in prostate cancer.
The Prostate 2011;71(6):604-14.
2011: Dennis J van de Wijngaart; Hendrikus J Dubbink; Michel Molier; Carola de Vos; Guido Jenster; Jan Trapman
Inhibition of androgen receptor functions by gelsolin FxxFF peptide delivered by transfection, cell-penetrating peptides, and lentiviral infection.
The Prostate 2011;71(3):241-53.
2011: Geert J L H van Leenders; Wytske M Van Weerden; Kees J Vissers; Corrina M A de Ridder; Suzanne Reneman; Andrea Sacchetti; Rajesh Sookhlall; Wilma J Teubel; Guido Jenster
Activation of c-MET induces a stem-like phenotype in human prostate cancer.
PloS one 2011;6(11):e26753.
2011: Rute B Marques; Wilfred F J van Ijcken; Wytske M Van Weerden; Natasja Dits; Sigrun Erkens-Schulze; Guido Jenster
Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines.
PloS one 2011;6(8):e23144.
2010: Lennard Dekker; Peter C Burgers; Halima Charif; Angelique L C T van Rijswijk; Mark K Titulaer; Guido Jenster; Rainer Bischoff; Chris H Bangma; Theo M Luider
Differential expression of protease activity in serum samples of prostate carcinoma patients with metastases.
Proteomics 2010;10(12):2348-58.
2010: Dennis J van de Wijngaart; Michel Molier; Scott J Lusher; Remko Hersmus; Guido Jenster; Jan Trapman; Hendrikus J Dubbink
Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.
The Journal of biological chemistry 2010;285(7):5097-105.
2010: Johannes Hofland; Wytske M Van Weerden; Natasja F J Dits; Jacobie Steenbergen; Geert J L H van Leenders; Guido Jenster; Fritz H Schröder; Frank de Jong
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer.
Cancer research 2010;70(3):1256-64.
2010: Rute B Marques; Natasja F Dits; Sigrun Erkens-Schulze; Wytske M Van Weerden; Guido Jenster
Bypass mechanisms of the androgen receptor pathway in therapy-resistant prostate cancer cell models.
PloS one 2010;5(10):e13500.
2009: Dennis J van de Wijngaart; Hendrikus J Dubbink; Michel Molier; Carola de Vos; Jan Trapman; Guido Jenster
Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.
Molecular endocrinology (Baltimore, Md.) 2009;23(11):1776-86.
2009: Karin G Hermans; Joost L Boormans; Delila Gasi; Geert J L H van Leenders; Guido Jenster; Paul C M S Verhagen; Jan Trapman
Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(20):6398-403.
2009: Leonie van der Heul-Nieuwenhuijsen; Natasja Dits; Wilfred Van Ijcken; Don de Lange; Guido Jenster
The FOXF2 pathway in the human prostate stroma.
The Prostate 2009;69(14):1538-47.
2009: Scott A Tomlins; Anders Bjartell; Arul M Chinnaiyan; Guido Jenster; Robert K Nam; Mark A Rubin; Jack A Schalken
ETS gene fusions in prostate cancer: from discovery to daily clinical practice.
European urology 2009;56(2):275-86.
2009: Leonie van der Heul-Nieuwenhuijsen; Natasja F Dits; Guido Jenster
Gene expression of forkhead transcription factors in the normal and diseased human prostate.
BJU international 2009;103(11):1574-80.
2009: Flip H Jansen; Jeroen Krijgsveld; Angelique van Rijswijk; Gert-Jan van den Bemd; Mirella S van den Berg; Wytske M Van Weerden; Rob Willemsen; Lennard Dekker; Theo M Luider; Guido Jenster
Exosomal secretion of cytoplasmic prostate cancer xenograft-derived proteins.
Molecular & cellular proteomics : MCP 2009;8(6):1192-205.
2009: Flip H Jansen; Monique J Roobol; Guido Jenster; Fritz H Schröder; Chris H Bangma
Screening for prostate cancer in 2008 II: the importance of molecular subforms of prostate-specific antigen and tissue kallikreins.
European urology 2009;55(3):563-74.
2009: Qiuping Ma; Wei Fu; Pengfei Li; Santo V Nicosia; Guido Jenster; Xiaohong Zhang; Wenlong Bai
FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment.
Molecular endocrinology (Baltimore, Md.) 2009;23(2):213-25.
2008: Karin G Hermans; Hetty van der Korput; Ronald van Marion; Dennis J van de Wijngaart; Angelique Ziel-van der Made; Natasja F Dits; Joost L Boormans; Theo Van der Kwast; Herman van Dekken; Chris H Bangma; Hanneke Korsten; Robert Kraaij; Guido Jenster; Jan Trapman
Truncated ETV1, fused to novel tissue-specific genes, and full-length ETV1 in prostate cancer.
Cancer research 2008;68(18):7541-9.
2008: Karin G Hermans; Anke A Bressers; Hetty van der Korput; Natasja F Dits; Guido Jenster; Jan Trapman
Two unique novel prostate-specific and androgen-regulated fusion partners of ETV4 in prostate cancer.
Cancer research 2008;68(9):3094-8.
2008: Rob Jelier; Martijn J Schuemie; Antoine Veldhoven; Lambert C J Dorssers; Guido Jenster; Jan A Kors
Anni 2.0: a multipurpose text-mining tool for the life sciences.
Genome biology 2008;9(6):R96.
2007: Andreas Römpp; Lennard Dekker; Ioana M Taban; Guido Jenster; Willem Boogerd; Hans Bonfrer; Bernhard Spengler; Ron M A Heeren; Peter Sillevis Smitt; Theo M Luider
Identification of leptomeningeal metastasis-related proteins in cerebrospinal fluid of patients with breast cancer by a combination of MALDI-TOF, MALDI-FTICR and nanoLC-FTICR MS.
Proteomics 2007;7(3):474-81.
2007: Rob Jelier; Guido Jenster; Lambert C J Dorssers; Bas J Wouters; Peter J M Hendriksen; Barend Mons; Ruud Delwel; Jan A Kors
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation.
BMC bioinformatics 2007;8():14.
2006: Karin G Hermans; Ronald van Marion; Herman van Dekken; Guido Jenster; Wytske M Van Weerden; Jan Trapman
TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.
Cancer research 2006;66(22):10658-63.
2006: Leonie van der Heul-Nieuwenhuijsen; Peter J M Hendriksen; Theo Van der Kwast; Guido Jenster
Gene expression profiling of the human prostate zones.
BJU international 2006;98(4):886-97.
2006: Gert-Jan C M van den Bemd; Jeroen Krijgsveld; Theo M Luider; Angelique L C T van Rijswijk; Jeroen A A Demmers; Guido Jenster
Mass spectrometric identification of human prostate cancer-derived proteins in serum of xenograft-bearing mice.
Molecular & cellular proteomics : MCP 2006;5(10):1830-9.
2006: Hendrikus J Dubbink; Remko Hersmus; Ashley C W Pike; Michel Molier; Albert O Brinkmann; Guido Jenster; Jan Trapman
Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1742-55.
2006: Chris H Bangma; Guido Jenster
Bladder carcinogenesis, in search of clues and genes.
European urology 2006;50(2):205-7.
2006: Dennis J van de Wijngaart; Martin E van Royen; Remko Hersmus; Ashley C W Pike; Adriaan B Houtsmuller; Guido Jenster; Jan Trapman; Hendrikus J Dubbink
Novel FXXFF and FXXMF motifs in androgen receptor cofactors mediate high affinity and specific interactions with the ligand-binding domain.
The Journal of biological chemistry 2006;281(28):19407-16.
2006: Peter J M Hendriksen; Natasja F J Dits; Koichi Kokame; Antoine Veldhoven; Wytske M Van Weerden; Chris H Bangma; Jan Trapman; Guido Jenster
Evolution of the androgen receptor pathway during progression of prostate cancer.
Cancer research 2006;66(10):5012-20.
2006: Rute B Marques; Wytske M Van Weerden; Sigrun Erkens-Schulze; Corrina M A de Ridder; Chris H Bangma; Jan Trapman; Guido Jenster
The human PC346 xenograft and cell line panel: a model system for prostate cancer progression.
European urology 2006;49(2):245-57.
2005: Rute B Marques; Sigrun Erkens-Schulze; Corrina M A de Ridder; Karin G Hermans; Kati K Waltering; Tapio Visakorpi; Jan Trapman; Johannes C Romijn; Wytske M Van Weerden; Guido Jenster
Androgen receptor modifications in prostate cancer cells upon long-termandrogen ablation and antiandrogen treatment.
International journal of cancer. Journal international du cancer 2005;117(2):221-9.
2005: Lennard Dekker; Willem Boogerd; Günther Stockhammer; Johannes C Dalebout; Ivar Siccama; Pingpin Zheng; Johannes M G Bonfrer; Jan J Verschuuren; Guido Jenster; Marcel M Verbeek; Theo M Luider; Peter A E Sillevis Smitt
MALDI-TOF mass spectrometry analysis of cerebrospinal fluid tryptic peptide profiles to diagnose leptomeningeal metastases in patients with breast cancer.
Molecular & cellular proteomics : MCP 2005;4(9):1341-9.
2005: Rob Jelier; Guido Jenster; Lambert C J Dorssers; Christiaan Van Der Eijk; Erik M Van Mulligen; Barend Mons; Jan A Kors
Co-occurrence based meta-analysis of scientific texts: retrieving biological relationships between genes.
Bioinformatics (Oxford, England) 2005;21(9):2049-58.
2005: Spiros Vlahopoulos; Warren Zimmer; Guido Jenster; Narasimhaswamy S Belaguli; Steven P Balk; Albert O Brinkmann; Rainer B Lanz; Vassilis C Zoumpourlis; Robert J Schwartz
Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene.
The Journal of biological chemistry 2005;280(9):7786-92.
2005: Antoine Veldhoven; Don de Lange; Marcel Smid; Victor de Jager; Jan A Kors; Guido Jenster
Storing, linking, and mining microarray databases using SRS.
BMC bioinformatics 2005;6():192.
2005: Blaise T F Alako; Antoine Veldhoven; Sjozef van Baal; Rob Jelier; Stefan Verhoeven; Ton Rullmann; Jan Polman; Guido Jenster
CoPub Mapper: mining MEDLINE based on search term co-publication.
BMC bioinformatics 2005;6():51.
2005: Lennard Dekker; Johannes C Dalebout; Ivar Siccama; Guido Jenster; Peter A E Sillevis Smitt; Theo M Luider
A new method to analyze matrix-assisted laser desorption/ionization time-of-flight peptide profiling mass spectra.
Rapid communications in mass spectrometry : RCM 2005;19(7):865-70.
2004: Glenn T G Chang; Mila Jhamai; Wytske M Van Weerden; Guido Jenster; Albert O Brinkmann
The TRPS1 transcription factor: androgenic regulation in prostate cancer and high expression in breast cancer.
Endocrine-related cancer 2004;11(4):815-22.
2004: Ding-Yen Lin; Hsin-I Fang; Ai-Hong Ma; Yen-Sung Huang; Yeong-Shiau Pu; Guido Jenster; Hsing-Jien Kung; Hsiu-Ming Shih
Negative modulation of androgen receptor transcriptional activity by Daxx.
Molecular and cellular biology 2004;24(24):10529-41.
2004: Cara Benjamin; Guido Jenster; Jorge A Piedrahita
Use of artificial androgen receptor coactivators to alter myoblast proliferation.
The Journal of steroid biochemistry and molecular biology 2004;91(3):111-9.
2004: Thomas R Salas; Jeri Kim; Funda Vakar-Lopez; Anita L Sabichi; Patricia Troncoso; Guido Jenster; Akira Kikuchi; Shao-Yong Chen; Lirim Shemshedini; Milind Suraokar; Christopher J Logothetis; John DiGiovanni; Scott M Lippman; David G Menter
Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity.
The Journal of biological chemistry 2004;279(18):19191-200.
2004: Guido Jenster
A visualisation concept of dynamic signalling networks.
Molecular and cellular endocrinology 2004;218(1-2):1-6.
2003: Marcel Smid; Lambert C J Dorssers; Guido Jenster
Venn Mapping: clustering of heterologous microarray data based on the number of co-occurring differentially expressed genes.
Bioinformatics (Oxford, England) 2003;19(16):2065-71.
2003: Rob Jelier; Guido Jenster; Lambert C J Dorssers; Erik M Van Mulligen; Barend Mons; Jan A Kors
Mining microarray datasets aided by knowledge stored in literature.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2003;():879.
2003: Pengfei Li; Heehyoung Lee; Shaodong Guo; Terry G Unterman; Guido Jenster; Wenlong Bai
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.
Molecular and cellular biology 2003;23(1):104-18.
2001: Dillon Phan; X Sui; Dung-Tsa Chen; Sonia M Najjar; Guido Jenster; Sue-Hwa Lin
Androgen regulation of the cell-cell adhesion molecule-1 (Ceacam1) gene.
Molecular and cellular endocrinology 2001;184(1-2):115-23.
2001: K S Bramlett; N F Dits; X Sui; M C Jorge; X Zhu; Guido Jenster
Repression of androgen-regulated gene expression by dominant negative androgen receptors.
Molecular and cellular endocrinology 2001;183(1-2):19-28.
2000: Shan Lu; Guido Jenster; Daniel E Epner
Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex.
Molecular endocrinology (Baltimore, Md.) 2000;14(5):753-60.
1999: Thomas E Spencer; A G Stagg; Margaret M Joyce; Guido Jenster; C G Wood; Fuller W Bazer; Anne A Wiley; Frank Bartol
Discovery and characterization of endometrial epithelial messenger ribonucleic acids using the ovine uterine gland knockout model.
Endocrinology 1999;140(9):4070-80.
1999: Guido Jenster
The role of the androgen receptor in the development and progression of prostate cancer.
Seminars in oncology 1999;26(4):407-21.
1999: X Sui; K S Bramlett; M C Jorge; David A Swanson; Andrew C von Eschenbach; Guido Jenster
Specific androgen receptor activation by an artificial coactivator.
The Journal of biological chemistry 1999;274(14):9449-54.
1998: Guido Jenster
Coactivators and corepressors as mediators of nuclear receptor function: an update.
Molecular and cellular endocrinology 1998;143(1-2):1-7.
1997: TE Spencer; Guido Jenster; Mark M Burcin; C David Allis; J Zhou; C A Mizzen; Neil J McKenna; Sergio A Onate; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Steroid receptor coactivator-1 is a histone acetyltransferase.
Nature 1997;389(6647):194-8.
1997: Guido Jenster; TE Spencer; Mark M Burcin; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Steroid receptor induction of gene transcription: a two-step model.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):7879-84.
1997: H Shibata; TE Spencer; Sergio A Onate; Guido Jenster; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Recent progress in hormone research 1997;52():141-64; discussion 164-5.