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Thomas Jenuwein
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17
Peters, Antoine
14
Schotta, Gunnar
11
Opravil, Susanne
11
Kubicek, Stefan
11
Lachner, Monika
8
Laible, G
8
O'Carroll, Dónal
8
Reuter, Gunter
8
Sengupta, Roopsha
8
Mechtler, Karl
7
O'Sullivan, Roderick
7
Perez-Burgos, Laura
7
Grosschedl, Rudolf
5
Kohlmaier, Alexander
5
Martens, Joost
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All Publications
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2009: Trojer Patrick; Zhang Jin; Yonezawa Masato; Schmidt Andreas; Zheng Haiyan; Jenuwein Thomas; Reinberg Danny
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.
The Journal of biological chemistry 2009;284(13):8395-405.
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2009: Pauler Florian M; Sloane Mathew A; Huang Ru; Regha Kakkad; Koerner Martha V; Tamir Ido; Sommer Andreas; Aszodi Andras; Jenuwein Thomas; Barlow Denise P
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.
Genome research 2009;19(2):221-33.
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2008: Greeson Nikole T; Sengupta Roopsha; Arida Ahmad R; Jenuwein Thomas; Sanders Steven L
Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage.
The Journal of biological chemistry 2008;283(48):33168-74.
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2008: Pannetier Maëlle; Julien Eric; Schotta Gunnar; Tardat Mathieu; Sardet Claude; Jenuwein Thomas; Feil Robert
PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.
EMBO reports 2008;9(10):998-1005.
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2008: Schotta Gunnar; Sengupta Roopsha; Kubicek Stefan; Malin Stephen; Kauer Monika; Callén Elsa; Celeste Arkady; Pagani Michaela; Opravil Susanne; De La Rosa-Velazquez Inti A; Espejo Alexsandra; Bedford Mark T; Nussenzweig André; Busslinger Meinrad; Jenuwein Thomas
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Genes & development 2008;22(15):2048-61.
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2007: Benetti Roberta; Gonzalo Susana; Jaco Isabel; Schotta Gunnar; Klatt Peter; Jenuwein Thomas; Blasco María A
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.
The Journal of cell biology 2007;178(6):925-36.
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2007: Huang Jing; Sengupta Roopsha; Espejo Alexsandra B; Lee Min Gyu; Dorsey Jean A; Richter Mario; Opravil Susanne; Shiekhattar Ramin; Bedford Mark T; Jenuwein Thomas; Berger Shelley L
p53 is regulated by the lysine demethylase LSD1.
Nature 2007;449(7158):105-8.
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2007: Regha Kakkad; Sloane Mathew A; Huang Ru; Pauler Florian M; Warczok Katarzyna E; Melikant Balázs; Radolf Martin; Martens Joost H A; Schotta Gunnar; Jenuwein Thomas; Barlow Denise P
Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.
Molecular cell 2007;27(3):353-66.
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2007: Villa Raffaella; Pasini Diego; Gutierrez Arantxa; Morey Lluis; Occhionorelli Manuela; Viré Emmanuelle; Nomdedeu Josep F; Jenuwein Thomas; Pelicci Pier Giuseppe; Minucci Saverio; Fuks Francois; Helin Kristian; Di Croce Luciano
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Cancer cell 2007;11(6):513-25.
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2007: McGarvey Kelly M; Greene Eriko; Fahrner Jill A; Jenuwein Thomas; Baylin Stephen B
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.
Cancer research 2007;67(11):5097-102.
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2007: Rudolph Thomas; Yonezawa Masato; Lein Sandro; Heidrich Kathleen; Kubicek Stefan; Schäfer Christiane; Phalke Sameer; Walther Matthias; Schmidt Andreas; Jenuwein Thomas; Reuter Gunter
Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.
Molecular cell 2007;26(1):103-15.
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2007: Wissmann Melanie; Yin Na; Müller Judith M; Greschik Holger; Fodor Barna D; Jenuwein Thomas; Vogler Christine; Schneider Robert; Günther Thomas; Buettner Reinhard; Metzger Eric; Schüle Roland
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.
Nature cell biology 2007;9(3):347-53.
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2007: Kubicek Stefan; O'Sullivan Roderick J; August E Michael; Hickey Eugene R; Zhang Qiang; Teodoro Miguel L; Rea Stephen; Mechtler Karl; Kowalski Jennifer A; Homon Carol Ann; Kelly Terence A; Jenuwein Thomas
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Molecular cell 2007;25(3):473-81.
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2007: Takada Yuki; Isono Kyo-ichi; Shinga Jun; Turner James M A; Kitamura Hiroshi; Ohara Osamu; Watanabe Gen; Singh Prim B; Kamijo Takehiko; Jenuwein Thomas; Burgoyne Paul S; Koseki Haruhiko
Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes.
Development (Cambridge, England) 2007;134(3):579-90.
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2007: Ohm Joyce E; McGarvey Kelly M; Yu Xiaobing; Cheng Linzhao; Schuebel Kornel E; Cope Leslie; Mohammad Helai P; Chen Wei; Daniel Vincent C; Yu Wayne; Berman David M; Jenuwein Thomas; Pruitt Kevin; Sharkis Saul J; Watkins D Neil; Herman James G; Baylin Stephen B
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nature genetics 2007;39(2):237-42.
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2006: Huang Jing; Perez-Burgos Laura; Placek Brandon J; Sengupta Roopsha; Richter Mario; Dorsey Jean A; Kubicek Stefan; Opravil Susanne; Jenuwein Thomas; Berger Shelley L
Repression of p53 activity by Smyd2-mediated methylation.
Nature 2006;444(7119):629-32.
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2006: Schubert Daniel; Primavesi Lucia; Bishopp Anthony; Roberts Gethin; Doonan John; Jenuwein Thomas; Goodrich Justin
Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27.
The EMBO journal 2006;25(19):4638-49.
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2006: Jenuwein Thomas
The epigenetic magic of histone lysine methylation.
The FEBS journal 2006;273(14):3121-35.
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2006: Bradley Sean P; Kaminski Denise A; Peters Antoine H F M; Jenuwein Thomas; Stavnezer Janet
The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1179-88.
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2006: Schoeftner Stefan; Sengupta Aditya K; Kubicek Stefan; Mechtler Karl; Spahn Laura; Koseki Haruhiko; Jenuwein Thomas; Wutz Anton
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.
The EMBO journal 2006;25(13):3110-22.
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2006: Etchegaray Jean-Pierre; Yang Xiaoming; DeBruyne Jason P; Peters Antoine H F M; Weaver David R; Jenuwein Thomas; Reppert Steven M
The polycomb group protein EZH2 is required for mammalian circadian clock function.
The Journal of biological chemistry 2006;281(30):21209-15.
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2006: Fodor Barna D; Kubicek Stefan; Yonezawa Masato; O'Sullivan Roderick J; Sengupta Roopsha; Perez-Burgos Laura; Opravil Susanne; Mechtler Karl; Schotta Gunnar; Jenuwein Thomas
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.
Genes & development 2006;20(12):1557-62.
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2006: Shumaker Dale K; Dechat Thomas; Kohlmaier Alexander; Adam Stephen A; Bozovsky Matthew R; Erdos Michael R; Eriksson Maria; Goldman Anne E; Khuon Satya; Collins Francis S; Jenuwein Thomas; Goldman Robert D
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8703-8.
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2006: Fujimura Yu-ichi; Isono Kyo-ichi; Vidal Miguel; Endoh Mitsuhiro; Kajita Hiroshi; Mizutani-Koseki Yoko; Takihara Yoshihiro; van Lohuizen Maarten; Otte Arie; Jenuwein Thomas; Deschamps Jacqueline; Koseki Haruhiko
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
Development (Cambridge, England) 2006;133(12):2371-81.
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2006: Brinkman Arie B; Roelofsen Thijs; Pennings Sebastiaan W C; Martens Joost H A; Jenuwein Thomas; Stunnenberg Hendrik G
Histone modification patterns associated with the human X chromosome.
EMBO reports 2006;7(6):628-34.
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2006: McGarvey Kelly M; Fahrner Jill A; Greene Eriko; Martens Joost; Jenuwein Thomas; Baylin Stephen B
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Cancer research 2006;66(7):3541-9.
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2006: Kubicek S; Schotta G; Lachner M; Sengupta R; Kohlmaier A; Perez-Burgos L; Linderson Y; Martens J H A; O'Sullivan R J; Fodor B D; Yonezawa M; Peters A H F M; Jenuwein T
The role of histone modifications in epigenetic transitions during normal and perturbed development.
Ernst Schering Research Foundation workshop 2006;(57):1-27.
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2005: Koyanagi Madoka; Baguet Aurelie; Martens Joost; Margueron Raphael; Jenuwein Thomas; Bix Mark
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells.
The Journal of biological chemistry 2005;280(36):31470-7.
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2005: Braig Melanie; Lee Soyoung; Loddenkemper Christoph; Rudolph Cornelia; Peters Antoine H F M; Schlegelberger Brigitte; Stein Harald; Dörken Bernd; Jenuwein Thomas; Schmitt Clemens A
Oncogene-induced senescence as an initial barrier in lymphoma development.
Nature 2005;436(7051):660-5.
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2005: Bao Siqin; Miyoshi Naoki; Okamoto Ikuhiro; Jenuwein Thomas; Heard Edith; Azim Surani M
Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte.
EMBO reports 2005;6(8):748-54.
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2005: Naumann Kathrin; Fischer Andreas; Hofmann Ingo; Krauss Veiko; Phalke Sameer; Irmler Kristina; Hause Gerd; Aurich Anne-Cathleen; Dorn Rainer; Jenuwein Thomas; Reuter Gunter
Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.
The EMBO journal 2005;24(7):1418-29.
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2005: Fraga Mario F; Ballestar Esteban; Villar-Garea Ana; Boix-Chornet Manuel; Espada Jesus; Schotta Gunnar; Bonaldi Tiziana; Haydon Claire; Ropero Santiago; Petrie Kevin; Iyer N Gopalakrishna; Pérez-Rosado Alberto; Calvo Enrique; Lopez Juan A; Cano Amparo; Calasanz Maria J; Colomer Dolors; Piris Miguel Angel; Ahn Natalie; Imhof Axel; Caldas Carlos; Jenuwein Thomas; Esteller Manel
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Nature genetics 2005;37(4):391-400.
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2005: Gonzalo Susana; García-Cao Marta; Fraga Mario F; Schotta Gunnar; Peters Antoine H F M; Cotter Shane E; Eguía Raúl; Dean Douglas C; Esteller Manel; Jenuwein Thomas; Blasco María A
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.
Nature cell biology 2005;7(4):420-8.
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2005: Kanellopoulou Chryssa; Muljo Stefan A; Kung Andrew L; Ganesan Shridar; Drapkin Ronny; Jenuwein Thomas; Livingston David M; Rajewsky Klaus
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing.
Genes & development 2005;19(4):489-501.
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2005: Martens Joost H A; O'Sullivan Roderick J; Braunschweig Ulrich; Opravil Susanne; Radolf Martin; Steinlein Peter; Jenuwein Thomas
The profile of repeat-associated histone lysine methylation states in the mouse epigenome.
The EMBO journal 2005;24(4):800-12.
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2004: Kubicek Stefan; Jenuwein Thomas
A crack in histone lysine methylation.
Cell 2004;119(7):903-6.
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2004: Ebert Anja; Schotta Gunnar; Lein Sandro; Kubicek Stefan; Krauss Veiko; Jenuwein Thomas; Reuter Gunter
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila.
Genes & development 2004;18(23):2973-83.
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2004: Baxter Jonathan; Sauer Stephan; Peters Antoine; John Rosalind; Williams Ruth; Caparros Marie-Laure; Arney Katharine; Otte Arie; Jenuwein Thomas; Merkenschlager Matthias; Fisher Amanda G
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.
The EMBO journal 2004;23(22):4462-72.
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2004: Lindroth Anders M; Shultis David; Jasencakova Zuzana; Fuchs Jörg; Johnson Lianna; Schubert Daniel; Patnaik Debasis; Pradhan Sriharsa; Goodrich Justin; Schubert Ingo; Jenuwein Thomas; Khorasanizadeh Sepideh; Jacobsen Steven E
Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.
The EMBO journal 2004;23(21):4286-96.
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2004: Kohlmaier Alexander; Savarese Fabio; Lachner Monika; Martens Joost; Jenuwein Thomas; Wutz Anton
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation.
PLoS biology 2004;2(7):E171.
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2004: Schotta Gunnar; Lachner Monika; Sarma Kavitha; Ebert Anja; Sengupta Roopsha; Reuter Gunter; Reinberg Danny; Jenuwein Thomas
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.
Genes & development 2004;18(11):1251-62.
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2004: Kuzmichev Andrei; Jenuwein Thomas; Tempst Paul; Reinberg Danny
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3.
Molecular cell 2004;14(2):183-93.
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2004: Jackson James P; Johnson Lianna; Jasencakova Zuzana; Zhang Xing; PerezBurgos Laura; Singh Prim B; Cheng Xiaodong; Schubert Ingo; Jenuwein Thomas; Jacobsen Steven E
Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.
Chromosoma 2004;112(6):308-15.
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2004: García-Cao Marta; O'Sullivan Roderick; Peters Antoine H F M; Jenuwein Thomas; Blasco María A
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.
Nature genetics 2004;36(1):94-9.
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2004: Lachner M; Sengupta R; Schotta G; Jenuwein T
Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome.
Cold Spring Harbor symposia on quantitative biology 2004;69():209-18.
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2004: Schotta Gunnar; Lachner Monika; Peters Antoine H F M; Jenuwein Thomas
The indexing potential of histone lysine methylation.
Novartis Foundation symposium 2004;259():22-37; discussion 37-47, 163-9.
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2004: Perez-Burgos Laura; Peters Antoine H F M; Opravil Susanne; Kauer Monika; Mechtler Karl; Jenuwein Thomas
Generation and characterization of methyl-lysine histone antibodies.
Methods in enzymology 2004;376():234-54.
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2003: Peters Antoine H F M; Kubicek Stefan; Mechtler Karl; O'Sullivan Roderick J; Derijck Alwin A H A; Perez-Burgos Laura; Kohlmaier Alexander; Opravil Susanne; Tachibana Makoto; Shinkai Yoichi; Martens Joost H A; Jenuwein Thomas
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.
Molecular cell 2003;12(6):1577-89.
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2003: Gilbert Nick; Boyle Shelagh; Sutherland Heidi; de Las Heras Jose; Allan James; Jenuwein Thomas; Bickmore Wendy A
Formation of facultative heterochromatin in the absence of HP1.
The EMBO journal 2003;22(20):5540-50.
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2003: Erhardt Sylvia; Su I-Hsin; Schneider Robert; Barton Sheila; Bannister Andrew J; Perez-Burgos Laura; Jenuwein Thomas; Kouzarides Tony; Tarakhovsky Alexander; Surani M Azim
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development.
Development (Cambridge, England) 2003;130(18):4235-48.
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2003: Lehnertz Bernhard; Ueda Yoshihide; Derijck Alwin A H A; Braunschweig Ulrich; Perez-Burgos Laura; Kubicek Stefan; Chen Taiping; Li En; Jenuwein Thomas; Peters Antoine H F M
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.
Current biology : CB 2003;13(14):1192-200.
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2003: Santos Fátima; Zakhartchenko Valeri; Stojkovic Miodrag; Peters Antoine; Jenuwein Thomas; Wolf Eckhard; Reik Wolf; Dean Wendy
Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.
Current biology : CB 2003;13(13):1116-21.
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2003: Lachner Monika; O'Sullivan Roderick J; Jenuwein Thomas
An epigenetic road map for histone lysine methylation.
Journal of cell science 2003;116(Pt 11):2117-24.
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2003: Silva Jose; Mak Winifred; Zvetkova Ilona; Appanah Ruth; Nesterova Tatyana B; Webster Zoe; Peters Antoine H F M; Jenuwein Thomas; Otte Arie P; Brockdorff Neil
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.
Developmental cell 2003;4(4):481-95.
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2003: Cheutin Thierry; McNairn Adrian J; Jenuwein Thomas; Gilbert David M; Singh Prim B; Misteli Tom
Maintenance of stable heterochromatin domains by dynamic HP1 binding.
Science (New York, N.Y.) 2003;299(5607):721-5.
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2002: Jenuwein Thomas
Molecular biology. An RNA-guided pathway for the epigenome.
Science (New York, N.Y.) 2002;297(5590):2215-8.
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2002: Sewalt Richard G A B; Lachner Monika; Vargas Mark; Hamer Karien M; den Blaauwen Jan L; Hendrix Thijs; Melcher Martin; Schweizer Dieter; Jenuwein Thomas; Otte Arie P
Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.
Molecular and cellular biology 2002;22(15):5539-53.
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2002: Lachner Monika; Jenuwein Thomas
The many faces of histone lysine methylation.
Current opinion in cell biology 2002;14(3):286-98.
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2002: Lagger Gerda; O'Carroll Dónal; Rembold Martina; Khier Harald; Tischler Julia; Weitzer Georg; Schuettengruber Bernd; Hauser Christoph; Brunmeir Reinhard; Jenuwein Thomas; Seiser Christian
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.
The EMBO journal 2002;21(11):2672-81.
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2002: Schotta Gunnar; Ebert Anja; Krauss Veiko; Fischer Andreas; Hoffmann Jan; Rea Stephen; Jenuwein Thomas; Dorn Rainer; Reuter Gunter
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
The EMBO journal 2002;21(5):1121-31.
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2002: Maison Christèle; Bailly Delphine; Peters Antoine H F M; Quivy Jean-Pierre; Roche Danièle; Taddei Angela; Lachner Monika; Jenuwein Thomas; Almouzni Geneviève
Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component.
Nature genetics 2002;30(3):329-34.
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2002: Mermoud Jacqueline E; Popova Bilyana; Peters Antoine H F M; Jenuwein Thomas; Brockdorff Neil
Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.
Current biology : CB 2002;12(3):247-51.
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2002: Peters Antoine H F M; Mermoud Jacqueline E; O'Carroll Dónal; Pagani Michaela; Schweizer Dieter; Brockdorff Neil; Jenuwein Thomas
Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.
Nature genetics 2002;30(1):77-80.
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2001: Peters A H; O'Carroll D; Scherthan H; Mechtler K; Sauer S; Schöfer C; Weipoltshammer K; Pagani M; Lachner M; Kohlmaier A; Opravil S; Doyle M; Sibilia M; Jenuwein T
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.
Cell 2001;107(3):323-37.
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2001: Czvitkovich S; Sauer S; Peters A H; Deiner E; Wolf A; Laible G; Opravil S; Beug H; Jenuwein T
Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice.
Mechanisms of development 2001;107(1-2):141-53.
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2001: Jenuwein T; Allis C D
Translating the histone code.
Science (New York, N.Y.) 2001;293(5532):1074-80.
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2001: Nielsen S J; Schneider R; Bauer U M; Bannister A J; Morrison A; O'Carroll D; Firestein R; Cleary M; Jenuwein T; Herrera R E; Kouzarides T
Rb targets histone H3 methylation and HP1 to promoters.
Nature 2001;412(6846):561-5.
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2001: O'Carroll D; Erhardt S; Pagani M; Barton S C; Surani M A; Jenuwein T
The polycomb-group gene Ezh2 is required for early mouse development.
Molecular and cellular biology 2001;21(13):4330-6.
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2001: Jenuwein T
Re-SET-ting heterochromatin by histone methyltransferases.
Trends in cell biology 2001;11(6):266-73.
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2001: Lachner M; O'Carroll D; Rea S; Mechtler K; Jenuwein T
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Nature 2001;410(6824):116-20.
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2000: O'Carroll D; Scherthan H; Peters A H; Opravil S; Haynes A R; Laible G; Rea S; Schmid M; Lebersorger A; Jerratsch M; Sattler L; Mattei M G; Denny P; Brown S D; Schweizer D; Jenuwein T
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.
Molecular and cellular biology 2000;20(24):9423-33.
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2000: Rea S; Eisenhaber F; O'Carroll D; Strahl B D; Sun Z W; Schmid M; Opravil S; Mechtler K; Ponting C P; Allis C D; Jenuwein T
Regulation of chromatin structure by site-specific histone H3 methyltransferases.
Nature 2000;406(6796):593-9.
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2000: Melcher M; Schmid M; Aagaard L; Selenko P; Laible G; Jenuwein T
Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.
Molecular and cellular biology 2000;20(10):3728-41.
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2000: Aagaard L; Schmid M; Warburton P; Jenuwein T
Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres.
Journal of cell science 2000;113 ( Pt 5)():817-29.
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1999: Aagaard L; Laible G; Selenko P; Schmid M; Dorn R; Schotta G; Kuhfittig S; Wolf A; Lebersorger A; Singh P B; Reuter G; Jenuwein T
Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.
The EMBO journal 1999;18(7):1923-38.
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1999: Laible G; Haynes A R; Lebersorger A; O'Carroll D; Mattei M G; Denny P; Brown S D; Jenuwein T
The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(3):311-4.
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1998: Jenuwein T; Laible G; Dorn R; Reuter G
SET domain proteins modulate chromatin domains in eu- and heterochromatin.
Cellular and molecular life sciences : CMLS 1998;54(1):80-93.
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1998: Fernández L A; Winkler M; Forrester W; Jenuwein T; Grosschedl R
Nuclear matrix attachment regions confer long-range function upon the immunoglobulin mu enhancer.
Cold Spring Harbor symposia on quantitative biology 1998;63():515-24.
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1997: Laible G; Wolf A; Dorn R; Reuter G; Nislow C; Lebersorger A; Popkin D; Pillus L; Jenuwein T
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.
The EMBO journal 1997;16(11):3219-32.
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1997: Jenuwein T; Forrester W C; Fernández-Herrero L A; Laible G; Dull M; Grosschedl R
Extension of chromatin accessibility by nuclear matrix attachment regions.
Nature 1997;385(6613):269-72.
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1995: Yuan D; Dang T; Hawley J; Jenuwein T; Grosschedl R
Role of the OCTA site in regulation of IgH chain gene transcription during B cell activation.
International immunology 1995;7(8):1163-72.
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1994: Forrester W C; van Genderen C; Jenuwein T; Grosschedl R
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions.
Science (New York, N.Y.) 1994;265(5176):1221-5.
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1993: Jenuwein T; Forrester W C; Qiu R G; Grosschedl R
The immunoglobulin mu enhancer core establishes local factor access in nuclear chromatin independent of transcriptional stimulation.
Genes & development 1993;7(10):2016-32.
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1993: Jenuwein T; Forrester W; Grosschedl R
Role of enhancer sequences in regulating accessibility of DNA in nuclear chromatin.
Cold Spring Harbor symposia on quantitative biology 1993;58():97-103.
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1991: Jenuwein T; Grosschedl R
Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.
Genes & development 1991;5(6):932-43.
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