FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Thomas Jenuwein

Research Profile

Chemicals & Drugs

Phenomena

Methylation

Living Beings

Mouse

Anatomy

Physiology

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Amino Acid Sequences

Co-author Network

Publications

TOP 3
Aydan Bulut-Karslioglu; Inti Alberto de la Rosa-Velazquez; Borbala Gerle; Thomas Brabletz; Monika Lachner; Thomas Manke; Simone Meidhof; Susanne Opravil; Michaela Pagani; Valentina Perrera; Johannes Popow; Manuela Scaranaro; Nicholas Shukeir; Suzanne van de Nobelen; Thomas Jenuwein
A transcription factor-based mechanism for mouse heterochromatin formation.
Inês Pinheiro; Danny Reinberg; Florian M Richter; Nicholas Shukeir; Jinsook Son; Michael Eisold; Christoph Fritzsch; Christel Genoud; Susumu Goyama; Mineo Kurokawa; Monika Lachner; Raphael Margueron; Gerhard Mittler; Thomas Jenuwein
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Julia Arand; Miguel R Branco; Thomas Jenuwein; Tommy Karius; Heinrich Leonhardt; Daniela Meilinger; Alexander Meissner; David Spieler; Verena Wolf; Guoliang Xu; Jörn Walter
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Thomas Jenuwein (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Aydan Bulut-Karslioglu; Inti Alberto de la Rosa-Velazquez; Borbala Gerle; Thomas Brabletz; Monika Lachner; Thomas Manke; Simone Meidhof; Susanne Opravil; Michaela Pagani; Valentina Perrera; Johannes Popow; Manuela Scaranaro; Nicholas Shukeir; Suzanne van de Nobelen; Thomas Jenuwein
A transcription factor-based mechanism for mouse heterochromatin formation.
Nature structural & molecular biology 2012;19(10):1023-30.
2012: Inês Pinheiro; Danny Reinberg; Florian M Richter; Nicholas Shukeir; Jinsook Son; Michael Eisold; Christoph Fritzsch; Christel Genoud; Susumu Goyama; Mineo Kurokawa; Monika Lachner; Raphael Margueron; Gerhard Mittler; Thomas Jenuwein
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Cell 2012;150(5):948-60.
2012: Julia Arand; Miguel R Branco; Thomas Jenuwein; Tommy Karius; Heinrich Leonhardt; Daniela Meilinger; Alexander Meissner; David Spieler; Verena Wolf; Guoliang Xu; Jörn Walter
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.
PLoS genetics 2012;8(6):e1002750.
2011: Chunyu Jin; Philipp Khaitovich; Jing Li; Jiancheng Liu; Nicholas Shukeir; Xia Tang; Dan Wang; Bo Xian; Zheng Yan; Xiaoming Yu; Hong Zhang; Xiongwen Cao; Charlie D Chen; Christopher D Green; Dali Han; Lei Hou; Xinxin Huang; Thomas Jenuwein; Jing-Dong J Han
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway.
Cell metabolism 2011;14(2):161-72.
2011: Falong Lu; Shuaibin Zhang; Xia Cui; Thomas Jenuwein; Xiaofeng Cao
Arabidopsis REF6 is a histone H3 lysine 27 demethylase.
Nature genetics 2011;43(7):715-9.
2010: Lihong Chen; Zhenyu Li; Aleksandra K Zwolinska; Matthew A Smith; Brittany Cross; John Koomen; Zhi-Min Yuan; Thomas Jenuwein; Jean-Christophe Marine; Kenneth L Wright; Jiandong Chen
MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output.
The EMBO journal 2010;29(15):2538-52.
2010: Weijun Feng; Masato Yonezawa; Jing Ye; Thomas Jenuwein; Ingrid Grummt
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.
Nature structural & molecular biology 2010;17(4):445-50.
2010: Jing Huang; Jean Dorsey; Sergei Chuikov; Laura Pérez-Burgos; Xinyue Zhang; Thomas Jenuwein; Danny Reinberg; SL Berger
G9a and Glp methylate lysine 373 in the tumor suppressor p53.
The Journal of biological chemistry 2010;285(13):9636-41.
2010: Maurice Reimann; Soyoung Lee; Christoph Loddenkemper; Jan R Dörr; Vedrana Tabor; Peter Aichele; Harald Stein; Bernd Dörken; Thomas Jenuwein; Clemens A Schmitt
Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Cancer cell 2010;17(3):262-72.
2010: Barna D Fodor; Nicholas Shukeir; Gunter Reuter; Thomas Jenuwein
Mammalian Su(var) genes in chromatin control.
Annual review of cell and developmental biology 2010;26():471-501.
2009: Fabio Savarese; Amparo Dávila; Robert Nechanitzky; Inti De La Rosa Velázquez; Carlos Filipe Pereira; Rudolf Engelke; Keiko Takahashi; Thomas Jenuwein; Terumi Kohwi-Shigematsu; Amanda G Fisher; Rudolf Grosschedl
Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression.
Genes & development 2009;23(22):2625-38.
2009: Patrick Trojer; Jin Zhang; Masato Yonezawa; Andreas Schmidt; Haiyan Zheng; Thomas Jenuwein; Danny Reinberg
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.
The Journal of biological chemistry 2009;284(13):8395-405.
2009: Florian M Pauler; Mathew A Sloane; Ru Huang; Kakkad Regha; Martha V Koerner; Ido Tamir; Andreas Sommer; Andras Aszodi; Thomas Jenuwein; Denise P Barlow
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.
Genome research 2009;19(2):221-33.
2008: Nikole T Greeson; Roopsha Sengupta; Ahmad R Arida; Thomas Jenuwein; Steven Sanders
Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage.
The Journal of biological chemistry 2008;283(48):33168-74.
2008: Maëlle Pannetier; Eric Julien; Gunnar Schotta; Mathieu Tardat; Claude Sardet; Thomas Jenuwein; Robert Feil
PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.
EMBO reports 2008;9(10):998-1005.
2008: Gunnar Schotta; Roopsha Sengupta; Stefan Kubicek; Stephen Malin; Monika Kauer; Elsa Callén; Arkady Celeste; Michaela Pagani; Susanne Opravil; Inti De La Rosa Velázquez; Alexsandra Espejo; Mark T Bedford; André Nussenzweig; Meinrad Busslinger; Thomas Jenuwein
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Genes & development 2008;22(15):2048-61.
2007: Roberta Benetti; Susana Gonzalo; Isabel Jaco; Gunnar Schotta; Peter Klatt; Thomas Jenuwein; María A Blasco
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.
The Journal of cell biology 2007;178(6):925-36.
2007: Jing Huang; Roopsha Sengupta; Alexsandra B Espejo; Min Gyu Lee; Jean A Dorsey; Mario Richter; Susanne Opravil; Ramin Shiekhattar; Mark T Bedford; Thomas Jenuwein; Shelley L Berger
p53 is regulated by the lysine demethylase LSD1.
Nature 2007;449(7158):105-8.
2007: Kakkad Regha; Mathew A Sloane; Ru Huang; Florian M Pauler; Katarzyna E Warczok; Balázs Melikant; Martin Radolf; Joost H A Martens; Gunnar Schotta; Thomas Jenuwein; Denise P Barlow
Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.
Molecular cell 2007;27(3):353-66.
2007: Raffaella Villa; Diego Pasini; Arantxa Gutierrez; Lluis Morey; Manuela Occhionorelli; Emmanuelle Viré; Josep F Nomdedeu; Thomas Jenuwein; Pier Giuseppe Pelicci; Saverio Minucci; François Fuks; Kristian Helin; Luciano Di Croce
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Cancer cell 2007;11(6):513-25.
2007: Kelly M McGarvey; Eriko Greene; Jill A Fahrner; Thomas Jenuwein; Stephen B Baylin
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.
Cancer research 2007;67(11):5097-102.
2007: Thomas Rudolph; Masato Yonezawa; Sandro Lein; Kathleen Heidrich; Stefan Kubicek; Christiane Schäfer; Sameer Phalke; Matthias Walther; Andreas Schmidt; Thomas Jenuwein; Gunter Reuter
Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.
Molecular cell 2007;26(1):103-15.
2007: Melanie Wissmann; Na Yin; Judith M Müller; Holger Greschik; Barna D Fodor; Thomas Jenuwein; Christine Vogler; Robert Schneider; Thomas Günther; Reinhard Buettner; Eric Metzger; Roland Schüle
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.
Nature cell biology 2007;9(3):347-53.
2007: Stefan Kubicek; Roderick J O'Sullivan; E Michael August; Eugene R Hickey; Qiang Zhang; Miguel L Teodoro; Stephen Rea; Karl Mechtler; Jennifer A Kowalski; Carol Ann Homon; Terence A Kelly; Thomas Jenuwein
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Molecular cell 2007;25(3):473-81.
2007: Yuki Takada; Kyo-ichi Isono; Jun Shinga; James M A Turner; Hiroshi Kitamura; Osamu Ohara; Gen Watanabe; Prim B Singh; Takehiko Kamijo; Thomas Jenuwein; Paul S Burgoyne; Haruhiko Koseki
Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes.
Development (Cambridge, England) 2007;134(3):579-90.
2007: Joyce E Ohm; Kelly M McGarvey; Xiaobing Yu; Linzhao Cheng; Kornel E Schuebel; Leslie Cope; Helai P Mohammad; Wei Chen; Vincent C Daniel; Wayne Yu; berman david; Thomas Jenuwein; Kevin Pruitt; Saul J Sharkis; DAVID WATKINS; James G Herman; Stephen B Baylin
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nature genetics 2007;39(2):237-42.
2006: Jing Huang; Laura Perez-Burgos; Brandon J Placek; Roopsha Sengupta; Mario Richter; Jean A Dorsey; Stefan Kubicek; Susanne Opravil; Thomas Jenuwein; Shelley L Berger
Repression of p53 activity by Smyd2-mediated methylation.
Nature 2006;444(7119):629-32.
2006: Daniel Schubert; Lucia Primavesi; Anthony Bishopp; Gethin Roberts; John H Doonan; Thomas Jenuwein; Justin Goodrich
Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27.
The EMBO journal 2006;25(19):4638-49.
2006: Jean-Pierre Etchegaray; Xiaoming Yang; Jason DeBruyne; Antoine H F M Peters; David R Weaver; Thomas Jenuwein; Steven M Reppert
The polycomb group protein EZH2 is required for mammalian circadian clock function.
The Journal of biological chemistry 2006;281(30):21209-15.
2006: Sean P Bradley; Denise A Kaminski; Antoine H F M Peters; Thomas Jenuwein; Janet Stavnezer
The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1179-88.
2006: Stefan Schoeftner; Aditya K Sengupta; Stefan Kubicek; Karl Mechtler; Laura Spahn; Haruhiko Koseki; Thomas Jenuwein; Anton Wutz
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.
The EMBO journal 2006;25(13):3110-22.
2006: Thomas Jenuwein
The epigenetic magic of histone lysine methylation.
The FEBS journal 2006;273(14):3121-35.
2006: Barna D Fodor; Stefan Kubicek; Masato Yonezawa; Roderick J O'Sullivan; Roopsha Sengupta; Laura Perez-Burgos; Susanne Opravil; Karl Mechtler; Gunnar Schotta; Thomas Jenuwein
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.
Genes & development 2006;20(12):1557-62.
2006: Dale K Shumaker; Thomas Dechat; Alexander Kohlmaier; Stephen Adam; Matthew R Bozovsky; Michael R Erdos; Maria Eriksson; Anne E Goldman; Satya Khuon; Francis S Collins; Thomas Jenuwein; Robert D Goldman
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8703-8.
2006: Yu-ichi Fujimura; Kyo-ichi Isono; Miguel Vidal; Mitsuhiro Endoh; Hiroshi Kajita; Yoko Mizutani-Koseki; Yoshihiro Takihara; Maarten van Lohuizen; Arie Otte; Thomas Jenuwein; Jacqueline Deschamps; Haruhiko Koseki
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
Development (Cambridge, England) 2006;133(12):2371-81.
2006: Arie B Brinkman; Thijs Roelofsen; Sebastiaan W C Pennings; Joost H A Martens; Thomas Jenuwein; Hendrik G Stunnenberg
Histone modification patterns associated with the human X chromosome.
EMBO reports 2006;7(6):628-34.
2006: Kelly M McGarvey; Jill A Fahrner; Eriko Greene; Joost Martens; Thomas Jenuwein; Stephen B Baylin
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Cancer research 2006;66(7):3541-9.
2006: Stefan Kubicek; Gunnar Schotta; Monika Lachner; Roopsha Sengupta; Alexander Kohlmaier; Laura Perez-Burgos; Y Linderson; Joost H A Martens; Roderick J O'Sullivan; Barna D Fodor; Masato Yonezawa; Antoine H F M Peters; Thomas Jenuwein
The role of histone modifications in epigenetic transitions during normal and perturbed development.
Ernst Schering Research Foundation workshop 2006;(57):1-27.
2005: Madoka Koyanagi; Aurelie Baguet; Joost Martens; Raphael Margueron; Thomas Jenuwein; Mark Bix
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells.
The Journal of biological chemistry 2005;280(36):31470-7.
2005: Melanie Braig; Soyoung Lee; Christoph Loddenkemper; Cornelia Rudolph; Antoine H F M Peters; Brigitte Schlegelberger; Harald Stein; Bernd Dörken; Thomas Jenuwein; Clemens A Schmitt
Oncogene-induced senescence as an initial barrier in lymphoma development.
Nature 2005;436(7051):660-5.
2005: Siqin Bao; Naoki Miyoshi; Ikuhiro Okamoto; Thomas Jenuwein; Edith Heard; M Azim Surani
Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte.
EMBO reports 2005;6(8):748-54.
2005: Kathrin Naumann; Andreas Fischer; Ingo Hofmann; Veiko Krauss; Sameer Phalke; Kristina Irmler; Gerd Hause; Anne-Cathleen Aurich; Rainer Dorn; Thomas Jenuwein; Gunter Reuter
Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.
The EMBO journal 2005;24(7):1418-29.
2005: Mario F Fraga; Esteban Ballestar; Ana Villar-Garea; Manuel Boix-Chornet; Jesus Espada; Gunnar Schotta; Tiziana Bonaldi; Claire Haydon; Santiago Ropero; Kevin Petrie; N Gopalakrishna Iyer; Alberto Pérez-Rosado; Enrique Calvo; Juan A Lopez; Amparo Cano; María J Calasanz; Dolors Colomer; Miguel A Piris; Natalie Ahn; Axel imhof; Carlos Caldas; Thomas Jenuwein; Manel Esteller
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Nature genetics 2005;37(4):391-400.
2005: Susana Gonzalo; Marta García-Cao; Mario F Fraga; Gunnar Schotta; Antoine H F M Peters; Shane E Cotter; Raúl Eguía; Douglas C Dean; Manel Esteller; Thomas Jenuwein; María A Blasco
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.
Nature cell biology 2005;7(4):420-8.
2005: Joost H A Martens; Roderick J O'Sullivan; Ulrich Braunschweig; Susanne Opravil; Martin Radolf; Peter Steinlein; Thomas Jenuwein
The profile of repeat-associated histone lysine methylation states in the mouse epigenome.
The EMBO journal 2005;24(4):800-12.
2005: Chrysi Kanellopoulou; Stefan A Muljo; Andrew L Kung; Shridar Ganesan; Ronny Drapkin; Thomas Jenuwein; David M Livingston; Klaus Rajewsky
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing.
Genes & development 2005;19(4):489-501.
2004: Stefan Kubicek; Thomas Jenuwein
A crack in histone lysine methylation.
Cell 2004;119(7):903-6.
2004: Anja Ebert; Gunnar Schotta; Sandro Lein; Stefan Kubicek; Veiko Krauss; Thomas Jenuwein; Gunter Reuter
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila.
Genes & development 2004;18(23):2973-83.
2004: Jonathan Baxter; Stephan Sauer; Antoine Peters; Rosalind John; Ruth Williams; Marie-Laure Caparros; Katharine L Arney; Arie Otte; Thomas Jenuwein; Matthias Merkenschlager; Amanda G Fisher
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.
The EMBO journal 2004;23(22):4462-72.
2004: Anders M Lindroth; david shultis; Zuzana Jasencakova; Jörg Fuchs; Lianna Johnson; Daniel Schubert; Debasis Patnaik; george feehehery; Justin Goodrich; Ingo Schubert; Thomas Jenuwein; Sepideh Khorasanizadeh; Steven E Jacobsen
Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.
The EMBO journal 2004;23(21):4286-96.
2004: Alexander Kohlmaier; Fabio Savarese; Monika Lachner; Joost Martens; Thomas Jenuwein; Anton Wutz
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation.
PLoS biology 2004;2(7):E171.
2004: Gunnar Schotta; Monika Lachner; Kavitha Sarma; Anja Ebert; Roopsha Sengupta; Gunter Reuter; Danny Reinberg; Thomas Jenuwein
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.
Genes & development 2004;18(11):1251-62.
2004: Andrei Kuzmichev; Thomas Jenuwein; Paul Tempst; Danny Reinberg
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3.
Molecular cell 2004;14(2):183-93.
2004: James P Jackson; Lianna Johnson; Zuzana Jasencakova; Xing Zhang; Laura PerezBurgos; Prim B Singh; Xiaodong Cheng; Ingo Schubert; Thomas Jenuwein; Steven E Jacobsen
Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.
Chromosoma 2004;112(6):308-15.
2004: Monika Lachner; Roopsha Sengupta; Gunnar Schotta; Thomas Jenuwein
Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome.
Cold Spring Harbor symposia on quantitative biology 2004;69():209-18.
2004: Gunnar Schotta; Monika Lachner; Antoine H F M Peters; Thomas Jenuwein
The indexing potential of histone lysine methylation.
Novartis Foundation symposium 2004;259():22-37; discussion 37-47, 163-9.
2004: Laura Perez-Burgos; Antoine H F M Peters; Susanne Opravil; Monika Kauer; Karl Mechtler; Thomas Jenuwein
Generation and characterization of methyl-lysine histone antibodies.
Methods in enzymology 2004;376():234-54.
2004: Marta García-Cao; Roderick J O'Sullivan; Antoine H F M Peters; Thomas Jenuwein; María A Blasco
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.
Nature genetics 2004;36(1):94-9.
2003: Antoine H F M Peters; Stefan Kubicek; Karl Mechtler; Roderick J O'Sullivan; Alwin A H A Derijck; Laura Perez-Burgos; Alexander Kohlmaier; Susanne Opravil; Makoto Tachibana; Yoichi Shinkai; Joost H A Martens; Thomas Jenuwein
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.
Molecular cell 2003;12(6):1577-89.
2003: Nick Gilbert; Shelagh Boyle; Heidi G E Sutherland; Jose de Las Heras; James Allan; Thomas Jenuwein; Wendy A Bickmore
Formation of facultative heterochromatin in the absence of HP1.
The EMBO journal 2003;22(20):5540-50.
2003: Sylvia Erhardt; I-Hsin Su; Robert Schneider; Sheila Barton; Andrew J Bannister; Laura Perez-Burgos; Thomas Jenuwein; Tony Kouzarides; Alexander Tarakhovsky; M Azim Surani
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development.
Development (Cambridge, England) 2003;130(18):4235-48.
2003: Bernhard Lehnertz; Yoshihide Ueda; Alwin A H A Derijck; Ulrich Braunschweig; Laura Perez-Burgos; Stefan Kubicek; Taiping Chen; En Li; Thomas Jenuwein; Antoine H F M Peters
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.
Current biology : CB 2003;13(14):1192-200.
2003: Fátima Santos; Valeri Zakhartchenko; Miodrag Stojkovic; Antoine Peters; Thomas Jenuwein; Eckhard Wolf; Wolf Reik; Wendy Dean
Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.
Current biology : CB 2003;13(13):1116-21.
2003: Monika Lachner; Roderick J O'Sullivan; Thomas Jenuwein
An epigenetic road map for histone lysine methylation.
Journal of cell science 2003;116(Pt 11):2117-24.
2003: Jose Silva; Winifred Mak; Ilona Zvetkova; Ruth Appanah; Tatyana B Nesterova; Zoe Webster; Antoine H F M Peters; Thomas Jenuwein; Arie P Otte; Neil Brockdorff
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.
Developmental cell 2003;4(4):481-95.
2003: Thierry Cheutin; Adrian McNairn; Thomas Jenuwein; David M Gilbert; Prim B Singh; Tom Misteli
Maintenance of stable heterochromatin domains by dynamic HP1 binding.
Science (New York, N.Y.) 2003;299(5607):721-5.
2002: Thomas Jenuwein
Molecular biology. An RNA-guided pathway for the epigenome.
Science (New York, N.Y.) 2002;297(5590):2215-8.
2002: Richard G A B Sewalt; Monika Lachner; Mark Vargas; Karien M Hamer; Jan L den Blaauwen; Thijs Hendrix; Martin Melcher; Dieter Schweizer; Thomas Jenuwein; Arie P Otte
Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.
Molecular and cellular biology 2002;22(15):5539-53.
2002: Gerda Lagger; Dónal O'Carroll; Martina Rembold; Harald Khier; Julia Tischler; Georg Weitzer; Bernd Schuettengruber; Christoph Hauser; Reinhard Brunmeir; Thomas Jenuwein; Christian Seiser
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.
The EMBO journal 2002;21(11):2672-81.
2002: Monika Lachner; Thomas Jenuwein
The many faces of histone lysine methylation.
Current opinion in cell biology 2002;14(3):286-98.
2002: Gunnar Schotta; Anja Ebert; Veiko Krauss; Andreas Fischer; Jan Hoffmann; Stephen Rea; Thomas Jenuwein; Rainer Dorn; Gunter Reuter
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
The EMBO journal 2002;21(5):1121-31.
2002: Christèle Maison; Delphine Bailly; Antoine H F M Peters; Jean-Pierre Quivy; Danièle Roche; Angela Taddei; Monika Lachner; Thomas Jenuwein; Geneviève Almouzni
Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component.
Nature genetics 2002;30(3):329-34.
2002: Jacqueline E Mermoud; Bilyana Popova; Antoine H F M Peters; Thomas Jenuwein; Neil Brockdorff
Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.
Current biology : CB 2002;12(3):247-51.
2002: Antoine H F M Peters; Jacqueline E Mermoud; Dónal O'Carroll; Michaela Pagani; Dieter Schweizer; Neil Brockdorff; Thomas Jenuwein
Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.
Nature genetics 2002;30(1):77-80.
2001: Antoine H F M Peters; Dónal O'Carroll; Harry Scherthan; Karl Mechtler; S Sauer; Christian Schöfer; Klara Weipoltshammer; Michaela Pagani; Monika Lachner; Alexander Kohlmaier; Susanne Opravil; M Doyle; Maria Sibilia; Thomas Jenuwein
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.
Cell 2001;107(3):323-37.
2001: S Czvitkovich; S Sauer; Antoine H F M Peters; Eva Maria Deiner ; A Wolf; G Laible; Susanne Opravil; Hartmut Beug; Thomas Jenuwein
Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice.
Mechanisms of development 2001;107(1-2):141-53.
2001: Thomas Jenuwein; C D Allis
Translating the histone code.
Science (New York, N.Y.) 2001;293(5532):1074-80.
2001: Søren Nielsen; R Schneider; Uta-Maria Bauer; Andrew J Bannister; A Morrison; D O'Carroll; R Firestein; M Cleary; Thomas Jenuwein; R E Herrera; Tony Kouzarides
Rb targets histone H3 methylation and HP1 to promoters.
Nature 2001;412(6846):561-5.
2001: Dónal O'Carroll; Sylvia Erhardt; Michaela Pagani; Sheila C Barton; M Azim Surani; Thomas Jenuwein
The polycomb-group gene Ezh2 is required for early mouse development.
Molecular and cellular biology 2001;21(13):4330-6.
2001: Thomas Jenuwein
Re-SET-ting heterochromatin by histone methyltransferases.
Trends in cell biology 2001;11(6):266-73.
2001: Monika Lachner; Dónal O'Carroll; S Rea; Karl Mechtler; Thomas Jenuwein
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Nature 2001;410(6824):116-20.
2000: Dónal O'Carroll; Harry Scherthan; Antoine H F M Peters; Susanne Opravil; AR Haynes; G Laible; S Rea; M Schmid; A Lebersorger; Martin Jerratsch; L Sattler; M G Mattei; Paul Denny; Steve D M Brown; Dieter Schweizer; Thomas Jenuwein
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.
Molecular and cellular biology 2000;20(24):9423-33.
2000: S Rea; Frank Eisenhaber; Dónal O'Carroll; Brian D Strahl; Zu-Wen Sun; M Schmid; Susanne Opravil; Karl Mechtler; C P Ponting; C David Allis; Thomas Jenuwein
Regulation of chromatin structure by site-specific histone H3 methyltransferases.
Nature 2000;406(6796):593-9.
2000: Martin Melcher; M Schmid; L Aagaard; P Selenko; G Laible; Thomas Jenuwein
Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.
Molecular and cellular biology 2000;20(10):3728-41.
2000: L Aagaard; M Schmid; P Warburton; Thomas Jenuwein
Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres.
Journal of cell science 2000;113 ( Pt 5)():817-29.
1999: L Aagaard; G Laible; P Selenko; M Schmid; Rainer Dorn; Gunnar Schotta; S Kuhfittig; A Wolf; A Lebersorger; P B Singh; Gunter Reuter; Thomas Jenuwein
Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.
The EMBO journal 1999;18(7):1923-38.
1999: G Laible; AR Haynes; A Lebersorger; Dónal O'Carroll; M G Mattei; Paul Denny; Steve D M Brown; Thomas Jenuwein
The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(3):311-4.
1998: LA Fernández; M Winkler; WC Forrester; Thomas Jenuwein; Rudolf Grosschedl
Nuclear matrix attachment regions confer long-range function upon the immunoglobulin mu enhancer.
Cold Spring Harbor symposia on quantitative biology 1998;63():515-24.
1998: Thomas Jenuwein; G Laible; Rainer Dorn; Gunter Reuter
SET domain proteins modulate chromatin domains in eu- and heterochromatin.
Cellular and molecular life sciences : CMLS 1998;54(1):80-93.
1997: G Laible; A Wolf; Rainer Dorn; Gunter Reuter; Corey Nislow; A Lebersorger; D Popkin; Lorraine Pillus; Thomas Jenuwein
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.
The EMBO journal 1997;16(11):3219-32.
1997: Thomas Jenuwein; WC Forrester; L A Fernández-Herrero; G Laible; M Dull; Rudolf Grosschedl
Extension of chromatin accessibility by nuclear matrix attachment regions.
Nature 1997;385(6613):269-72.
1995: Dorothy Yuan; T Dang; J Hawley; Thomas Jenuwein; Rudolf Grosschedl
Role of the OCTA site in regulation of IgH chain gene transcription during B cell activation.
International immunology 1995;7(8):1163-72.
1994: W C Forrester; C van Genderen; Thomas Jenuwein; Rudolf Grosschedl
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions.
Science (New York, N.Y.) 1994;265(5176):1221-5.
1993: Thomas Jenuwein; W C Forrester; R G Qiu; Rudolf Grosschedl
The immunoglobulin mu enhancer core establishes local factor access in nuclear chromatin independent of transcriptional stimulation.
Genes & development 1993;7(10):2016-32.
1993: Thomas Jenuwein; W Forrester; Rudolf Grosschedl
Role of enhancer sequences in regulating accessibility of DNA in nuclear chromatin.
Cold Spring Harbor symposia on quantitative biology 1993;58():97-103.
1991: Thomas Jenuwein; Rudolf Grosschedl
Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.
Genes & development 1991;5(6):932-43.