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Keith Jerome

Research Profile

Procedures

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Cytotoxicity, Immunologic

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Publications

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Joshua T Schiffer; Stacy Selke; David Swan; Anna Wald; Jia Zhu; Ramzi Al Sallaq; Meei-Li Huang; Keith R Jerome; Christine Johnston; Steve Kuntz; Amalia Magaret; Karen E Mark; Negusse Ocbamichael; Barry Robinson; Lawrence Corey
Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract.
Summer L Day; Susan M Graham; Keith R Jerome; H Nina Kim; Kishorchandra N Mandaliya; Linnet N Masese; Katherine Odem-Davis; John Scott; Linda Cook; R Scott McClelland
Prevalence, clinical and virologic outcomes of hepatitis B virus co-infection in HIV-1 positive Kenyan women on antiretroviral therapy.
Min Xu; Danielle M Zerr; Michael L Astion; Anne Cent; John C Childs; Janet A Englund; Keith R Jerome; Russell T Migita; Xuan Qin; Shannon Rich; Joe C Rutledge; Joanne Simpson; Mark A Del Beccaro
Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care.

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All Publications

2013: Joshua T Schiffer; Stacy Selke; David Swan; Anna Wald; Jia Zhu; Ramzi Al Sallaq; Meei-Li Huang; Keith R Jerome; Christine Johnston; Steve Kuntz; Amalia Magaret; Karen E Mark; Negusse Ocbamichael; Barry Robinson; Lawrence Corey
Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract.
eLife 2013;2():e00288.
2013: Summer L Day; Susan M Graham; Keith R Jerome; H Nina Kim; Kishorchandra N Mandaliya; Linnet N Masese; Katherine Odem-Davis; John Scott; Linda Cook; R Scott McClelland
Prevalence, clinical and virologic outcomes of hepatitis B virus co-infection in HIV-1 positive Kenyan women on antiretroviral therapy.
PloS one 2013;8(3):e59346.
2013: Min Xu; Danielle M Zerr; Michael L Astion; Anne Cent; John C Childs; Janet A Englund; Keith R Jerome; Russell T Migita; Xuan Qin; Shannon Rich; Joe C Rutledge; Joanne Simpson; Mark A Del Beccaro
Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care.
American journal of clinical pathology 2013;139(1):118-23.
2013: Ruth Hall Sedlak; Keith R Jerome
Viral diagnostics in the era of digital polymerase chain reaction.
Diagnostic microbiology and infectious disease 2013;75(1):1-4.
2013: Thor A Wagner; Hélène C F Côté; Keith R Jerome; Chen-Han Lin; Derek D Sloan; Nicole H Tobin; Lisa M Frenkel
Quantification of mitochondrial toxicity in HIV-infected individuals by quantitative PCR compared to flow cytometry.
Cytometry. Part B, Clinical cytometry 2013;84(1):55-8.
2012: Linda Cook; Kurt Diem; Woo Kim; John D Scott; Keith R Jerome
Allele-specific PCR for determination of IL28B genotype.
Journal of clinical microbiology 2012;50(12):4144-6.
2011: Keith R Jerome; Stacy Selke; Lawrence Corey; Kurt Diem; Meei-Li Huang; Dedra Buchwald
Xenotropic murine leukemia virus-related virus in monozygotic twins discordant for chronic fatigue syndrome.
Diagnostic microbiology and infectious disease 2011;71(1):66-71.
2011: Chia C Wang; Linda Cook; Kenneth A Tapia; Sarah Holte; Meighan Krows; Arthur Bagabag; Anna Santos; Lawrence Corey; Keith R Jerome
Cervicovaginal shedding of hepatitis C viral RNA is associated with the presence of menstrual or other blood in cervicovaginal fluids.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;50(1):4-7.
2009: Martine Aubert; Miri Yoon; Derek D Sloan; Patricia G Spear; Keith R Jerome
The virological synapse facilitates herpes simplex virus entry into T cells.
Journal of virology 2009;83(12):6171-83.
2009: Linda Cook; Ederlyn E Atienza; Arthur Bagabag; Rose M Obrigewitch; Keith R Jerome
Comparison of methods for extraction of viral DNA from cellular specimens.
Diagnostic microbiology and infectious disease 2009;64(1):37-42.
2009: Chen-Han Lin; Derek D Sloan; Chung H Dang; Thor Wagner; Albert J E Cabrera; Nicole H Tobin; Lisa M Frenkel; Keith R Jerome
Assessment of mitochondrial toxicity by analysis of mitochondrial protein expression in mononuclear cells.
Cytometry. Part B, Clinical cytometry 2009;76(3):181-90.
2008: Noah G Hoffman; Linda Cook; Ederlyn E Atienza; Ajit P Limaye; Keith R Jerome
Marked variability of BK virus load measurement using quantitative real-time PCR among commonly used assays.
Journal of clinical microbiology 2008;46(8):2671-80.
2008: Keith R Jerome
Viral modulation of T-cell receptor signaling.
Journal of virology 2008;82(9):4194-204.
2008: Martine Aubert; Zheng Chen; Robin Lang; Chung H Dang; Carla Fowler; Derek D Sloan; Keith R Jerome
The antiapoptotic herpes simplex virus glycoprotein J localizes to multiple cellular organelles and induces reactive oxygen species formation.
Journal of virology 2008;82(2):617-29.
2007: Derek D Sloan; Keith R Jerome
Herpes simplex virus remodels T-cell receptor signaling, resulting in p38-dependent selective synthesis of interleukin-10.
Journal of virology 2007;81(22):12504-14.
2007: Jared Castor; Linda Cook; Lawrence Corey; Keith R Jerome
Rapid detection directly from patient serum samples of human cytomegalovirus UL97 mutations conferring ganciclovir resistance.
Journal of clinical microbiology 2007;45(8):2681-3.
2007: Jin-Young Han; Derek D Sloan; Martine Aubert; Sara A Miller; Chung H Dang; Keith R Jerome
Apoptosis and antigen receptor function in T and B cells following exposure to herpes simplex virus.
Virology 2007;359(2):253-63.
2006: Linda Cook; KaWing Sullivan; Elizabeth Krantz; Arthur Bagabag; Keith R Jerome
Multiplex real-time reverse transcription-PCR assay for determination of hepatitis C virus genotypes.
Journal of clinical microbiology 2006;44(11):4149-56.
2006: Derek D Sloan; Jin-Young Han; Tracy K Sandifer; Mary Stewart; Aaron J Hinz; Miri Yoon; David C Johnson; Patricia G Spear; Keith R Jerome
Inhibition of TCR signaling by herpes simplex virus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1825-33.
2006: Martine Aubert; Elizabeth Krantz; Keith R Jerome
Herpes simplex virus genes Us3, Us5, and Us12 differentially regulate cytotoxic T lymphocyte-induced cytotoxicity.
Viral immunology 2006;19(3):391-408.
2005: K Kay-Yin Lai; Linda Cook; Elizabeth Krantz; Lawrence Corey; Keith R Jerome
Calibration curves for real-time PCR.
Clinical chemistry 2005;51(7):1132-6.
2005: Paul A Carpenter; James Lowder; Laura Johnston; Haydar Frangoul; Hanna Khoury; Pablo Parker; Keith R Jerome; Jeannine S McCune; Barry Storer; Paul Martin; Frederick R Appelbaum; Rafat Abonour; Peter Westervelt; Claudio Anasetti
A phase II multicenter study of visilizumab, humanized anti-CD3 antibody, to treat steroid-refractory acute graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(6):465-71.
2005: Ajit P Limaye; Kelly D Smith; Linda Cook; Debra A Groom; Nicholas C Hunt; Keith R Jerome; Michael Boeckh
Polyomavirus nephropathy in native kidneys of non-renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(3):614-20.
2004: Linda Cook; Ka-Wing Ng; Arthur Bagabag; Lawrence Corey; Keith R Jerome
Use of the MagNA pure LC automated nucleic acid extraction system followed by real-time reverse transcription-PCR for ultrasensitive quantitation of hepatitis C virus RNA.
Journal of clinical microbiology 2004;42(9):4130-6.
2004: Keith R Jerome; D R Gretch
Laboratory approaches to the diagnosis of hepatitis C virus infection.
Minerva gastroenterologica e dietologica 2004;50(1):9-20.
2004: Shannon E Nesbitt; Linda Cook; Keith R Jerome
Cytomegalovirus quantitation by real-time PCR is unaffected by delayed separation of plasma from whole blood.
Journal of clinical microbiology 2004;42(3):1296-7.
2004: Keith R Jerome; Lawrence Corey
The danger within.
The New England journal of medicine 2004;350(4):411-2.
2003: Derek D Sloan; George Zahariadis; Christine M Posavad; Nichlos T Pate; Steven J Kussick; Keith R Jerome
CTL are inactivated by herpes simplex virus-infected cells expressing a viral protein kinase.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6733-41.
2003: Keith R Jerome; Derek D Sloan; Martine Aubert
Measurement of CTL-induced cytotoxicity: the caspase 3 assay.
Apoptosis : an international journal on programmed cell death 2003;8(6):563-71.
2003: Martine Aubert; Keith R Jerome
Apoptosis prevention as a mechanism of immune evasion.
International reviews of immunology 2003;22(5-6):361-71.
2003: George Zahariadis; Keith R Jerome; Lawrence Corey
Herpes simplex virus-associated sepsis in a previously infected immunocompetent adult.
Annals of internal medicine 2003;139(2):153-4.
2003: K Kay-Yin Lai; Linda Cook; Sharon Wendt; Lawrence Corey; Keith R Jerome
Evaluation of real-time PCR versus PCR with liquid-phase hybridization for detection of enterovirus RNA in cerebrospinal fluid.
Journal of clinical microbiology 2003;41(7):3133-41.
2003: Pradeep V Kadambi; Michelle A Josephson; James Williams; Lawrence Corey; Keith R Jerome; Shane M Meehan; Ajit P Limaye
Treatment of refractory BK virus-associated nephropathy with cidofovir.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(2):186-91.
2003: Keith R Jerome; Derek D Sloan; Martine Aubert
Measuring T-cell-mediated cytotoxicity using antibody to activated caspase 3.
Nature medicine 2003;9(1):4-5.
2003: Luwy Musey; Y Ding; Jianhong Cao; J Lee; C Galloway; A Yuen; Keith R Jerome; M Juliana McElrath
Ontogeny and specificities of mucosal and blood human immunodeficiency virus type 1-specific CD8(+) cytotoxic T lymphocytes.
Journal of virology 2003;77(1):291-300.
2002: Keith R Jerome; Meei-Li Huang; Anna Wald; Stacy Selke; Lawrence Corey
Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR.
Journal of clinical microbiology 2002;40(7):2609-11.
2001: Keith R Jerome; Zheng Chen; R Lang; M R Torres; J Hofmeister; S Smith; R Fox; C J Froelich; Lawrence Corey
HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3928-35.
2001: Ajit P Limaye; Keith R Jerome; Christian S Kuhr; James Ferrenberg; Meei-Li Huang; Connie L Davis; Lawrence Corey; Christopher L Marsh
Quantitation of BK virus load in serum for the diagnosis of BK virus-associated nephropathy in renal transplant recipients.
The Journal of infectious diseases 2001;183(11):1669-72.
2001: Charles E Murry; Keith R Jerome; Dennis D Reichenbach
Fatal parvovirus myocarditis in a 5-year-old girl.
Human pathology 2001;32(3):342-5.
2001: Keith R Jerome; R Fox; Zheng Chen; P Sarkar; Lawrence Corey
Inhibition of apoptosis by primary isolates of herpes simplex virus.
Archives of virology 2001;146(11):2219-25.
2000: Keith R Loeb; Keith R Jerome; J Goddard; M Huang; Anne Cent; Lawrence Corey
High-throughput quantitative analysis of hepatitis B virus DNA in serum using the TaqMan fluorogenic detection system.
Hepatology (Baltimore, Md.) 2000;32(3):626-9.
2000: Keith R Jerome; Claudio Vallan; Rolf Jaggi
The tunel assay in the diagnosis of graft-versus-host disease: caveats for interpretation.
Pathology 2000;32(3):186-90.
1999: Keith R Jerome; R Fox; Zheng Chen; A E Sears; H y Lee; Lawrence Corey
Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3.
Journal of virology 1999;73(11):8950-7.
1998: Keith R Jerome; S J Conyers; D A Hansen; John Zebala
Keratinocyte apoptosis following bone marrow transplantation: evidence for CTL-dependent and -independent pathways.
Bone marrow transplantation 1998;22(4):359-66.
1998: Keith R Jerome; Jonathan F Tait; David M Koelle; Lawrence Corey
Herpes simplex virus type 1 renders infected cells resistant to cytotoxic T-lymphocyte-induced apoptosis.
Journal of virology 1998;72(1):436-41.
1997: Keith R Jerome; Allan D Kirk; G Pecher; W W Ferguson; O J Finn
A survivor of breast cancer with immunity to MUC-1 mucin, and lactational mastitis.
Cancer immunology, immunotherapy : CII 1997;43(6):355-60.
1995: Olivera J Finn; Keith R Jerome; R A Henderson; G Pecher; N Domenech; J Magarian-Blander; Simon M Barratt-Boyes
MUC-1 epithelial tumor mucin-based immunity and cancer vaccines.
Immunological reviews 1995;145():61-89.
1993: Constantin G Ioannides; Bryan Fisk; Keith R Jerome; T Irimura; J Taylor Wharton; Olivera J Finn
Cytotoxic T cells from ovarian malignant tumors can recognize polymorphic epithelial mucin core peptides.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3693-703.
1993: Keith R Jerome; N Domenech; Olivera J Finn
Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(3):1654-62.
1992: Keith R Jerome; D Bu; Olivera J Finn
Expression of tumor-associated epitopes on Epstein-Barr virus-immortalized B-cells and Burkitt's lymphomas transfected with epithelial mucin complementary DNA.
Cancer research 1992;52(21):5985-90.
1991: Keith R Jerome; D L Barnd; K M Bendt; CM Boyer; J Taylor-Papadimitriou; I F McKenzie; Robert C Bast; Olivera J Finn
Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells.
Cancer research 1991;51(11):2908-16.