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Carmen Jerónimo

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Physiology

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Nelma Pértega-Gomes; José R Vizcaíno; Carlos Gouveia; Rui M Henrique; Carmen Jerónimo; Carlos Lopes; Fátima Baltazar
Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer.
Bárbara Mesquita; Deolinda Pereira; Ana Rodrigues; Mariana Afonso; Rui Henrique; Carmen Jerónimo; Conceição Leal; Guro E Lind; Paula Lopes; Ragnhild A Lothe; Manuel R Teixeira
Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes.
João Ramalho-Carvalho; Mário Resende; Patrícia Rocha; Joana Savva-Bordalo; Manuel Teixeira; João Diogo Barros-Silva; Inês Graça; Rui Henrique; Mrinalini Honavar; Susana Lisboa; Joaquina Maurício; Malini Pires; Carmen Jerónimo
Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations.

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2013: Nelma Pértega-Gomes; José R Vizcaíno; Carlos Gouveia; Rui M Henrique; Carmen Jerónimo; Carlos Lopes; Fátima Baltazar
Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer.
The Prostate 2013;73(7):763-9.
2013: Bárbara Mesquita; Deolinda Pereira; Ana Rodrigues; Mariana Afonso; Rui Henrique; Carmen Jerónimo; Conceição Leal; Guro E Lind; Paula Lopes; Ragnhild A Lothe; Manuel R Teixeira
Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes.
Breast cancer research and treatment 2013;138(1):37-45.
2013: João Ramalho-Carvalho; Mário Resende; Patrícia Rocha; Joana Savva-Bordalo; Manuel Teixeira; João Diogo Barros-Silva; Inês Graça; Rui Henrique; Mrinalini Honavar; Susana Lisboa; Joaquina Maurício; Malini Pires; Carmen Jerónimo
Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations.
PloS one 2013;8(3):e58206.
2012: Ana Isabel Oliveira; Carmen Jerónimo; Rui Henrique
Moving forward in bladder cancer detection and diagnosis: the role of epigenetic biomarkers.
Expert review of molecular diagnostics 2012;12(8):871-8.
2012: Paula Paulo; Franclim R Ribeiro; Joana Santos; Rolf Skotheim; Anita Sveen; Mafalda Almeida; João D Barros-Silva; Rui Henrique; Harri Itkonen; Carmen Jerónimo; Ragnhild A Lothe; Diana Mesquita; Ian G Mills; Manuel R Teixeira
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements.
Neoplasia (New York, N.Y.) 2012;14(7):600-11.
2012: Maria J Camões; Nuno Cerveira; Vera L Costa; Rui Henrique; Carmen Jerónimo; Ragnhild A Lothe; Paula Paulo; Franclim R Ribeiro; Rolf Skotheim; Mafalda Almeida; João D Barros-Silva; Manuel Teixeira
Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.
PloS one 2012;7(11):e49819.
2012: Rui Henrique; Ana Sílvia Luís; Carmen Jerónimo
The epigenetics of renal cell tumors: from biology to biomarkers.
Frontiers in genetics 2012;3():94.
2011: Carmen Jerónimo; William G Nelson; Patrick J Bastian; Anders Bjartell; Giuseppina M Carbone; James W F Catto; Susan J Clark; Rui Henrique; Shahrokh F Shariat
Epigenetics in prostate cancer: biologic and clinical relevance.
European urology 2011;60(4):753-66.
2011: Vera L Costa; Stine Aske Danielsen; Mette Eknaes; Rui Henrique; Guro E Lind; Ragnhild A Lothe; António Morais; Jorge Oliveira; Patrícia Patrício; Manuel R Teixeira; Carmen Jerónimo
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
Epigenetics : official journal of the DNA Methylation Society 2011;6(9):1120-30.
2011: João D Barros-Silva; Ricardo Cruz; Rui Henrique; Carmen Jerónimo; Ana T Martins; Franclim R Ribeiro; Angelo Rodrigues; Manuel Teixeira
Relative 8q gain predicts disease-specific survival irrespective of the TMPRSS2-ERG fusion status in diagnostic biopsies of prostate cancer.
Genes, chromosomes & cancer 2011;50(8):662-71.
2011: Ana Teresa Martins; Paula Monteiro; João Ramalho-Carvalho; Conceição Leal; Vera L Costa; Mario Dinis-Ribeiro; Rui Henrique; Carmen Jerónimo
High RASSF1A promoter methylation levels are predictive of poor prognosis in fine-needle aspirate washings of breast cancer lesions.
Breast cancer research and treatment 2011;129(1):1-9.
2011: Sara Duarte-Pereira; Filipa Paiva; Vera L Costa; João Ramalho-Carvalho; Joana Savva-Bordalo; Angelo Rodrigues; Franclim R Ribeiro; Vitor M Silva; Jorge Oliveira; Rui Henrique; Carmen Jerónimo
Prognostic value of opioid binding protein/cell adhesion molecule-like promoter methylation in bladder carcinoma.
European journal of cancer (Oxford, England : 1990) 2011;47(7):1106-14.
2011: Filipa Paiva; Sara Duarte-Pereira; Vera L Costa; João Ramalho-Carvalho; Patrícia Patrício; Franclim Ricardo Ribeiro; Francisco Lobo; Jorge Oliveira; Carmen Jerónimo; Rui Henrique
Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms.
DNA and cell biology 2011;30(2):85-90.
2011: Franclim R Ribeiro; Rolf Skotheim; João D Barros-Silva; Vera L Costa; Rui Henrique; Carmen Jerónimo; Guro E Lind; Ragnhild A Lothe; Paula Paulo; João Ramalho-Carvalho; Manuel Teixeira
Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.
PloS one 2011;6(7):e22317.
2011: Maria João Valente; Rui Henrique; Vera L Costa; Carmen Jerónimo; Félix Carvalho; Maria Lourdes Bastos; Paula Guedes de Pinho; Márcia Carvalho
A rapid and simple procedure for the establishment of human normal and cancer renal primary cell cultures from surgical specimens.
PloS one 2011;6(5):e19337.
2010: Vera L Costa; Rui Henrique; Stine A Danielsen; Sara Duarte-Pereira; Mette Eknaes; Rolf I Skotheim; Angelo Rodrigues; José S Magalhães; Jorge Oliveira; Ragnhild A Lothe; Manuel Teixeira; Carmen Jerónimo; Guro E Lind
Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(23):5842-51.
2010: Joana Vieira; Rui Henrique; Franclim R Ribeiro; João D Barros-Silva; Ana Peixoto; Catarina Santos; Manuela Pinheiro; Vera L Costa; Maria J Soares; Jorge Oliveira; Carmen Jerónimo; Manuel Teixeira
Feasibility of differential diagnosis of kidney tumors by comparative genomic hybridization of fine needle aspiration biopsies.
Genes, chromosomes & cancer 2010;49(10):935-47.
2010: Carmen Jerónimo; Manel Esteller
DNA methylation markers for prostate cancer with a stem cell twist.
Cancer prevention research (Philadelphia, Pa.) 2010;3(9):1053-5.
2010: João R Carvalho; Luísa Filipe; Vera L Costa; Franclim Ricardo Ribeiro; Ana T Martins; Manuel R Teixeira; Carmen Jerónimo; Rui Henrique
Detailed analysis of expression and promoter methylation status of apoptosis-related genes in prostate cancer.
Apoptosis : an international journal on programmed cell death 2010;15(8):956-65.
2010: Vera L Costa; Rui Henrique; Franclim R Ribeiro; João R Carvalho; Jorge Oliveira; Francisco Lobo; Manuel R Teixeira; Carmen Jerónimo
Epigenetic regulation of Wnt signaling pathway in urological cancer.
Epigenetics : official journal of the DNA Methylation Society 2010;5(4):343-51.
2010: Joana Savva-Bordalo; João Ramalho-Carvalho; Manuela Pinheiro; Vera L Costa; Angelo Rodrigues; Paula C Dias; Isabel Veiga; Manuela Machado; Manuel Teixeira; Rui Henrique; Carmen Jerónimo
Promoter methylation and large intragenic rearrangements of DPYD are not implicated in severe toxicity to 5-fluorouracil-based chemotherapy in gastrointestinal cancer patients.
BMC cancer 2010;10():470.
2010: Márcia Carvalho; Pedro J Ferreira; Vanda S Mendes; Renata Silva; José Pereira; Carmen Jerónimo; Branca M Silva
Human cancer cell antiproliferative and antioxidant activities of Juglans regia L.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(1):441-7.
2009: Maria J Soares; Mafalda Pinto; Rui Henrique; Joana Vieira; Nuno Cerveira; Ana Peixoto; Ana T Martins; Jorge Oliveira; Carmen Jerónimo; Manuel Teixeira
CSF1R copy number changes, point mutations, and RNA and protein overexpression in renal cell carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(6):744-52.
2008: Mafalda Pinto; Joana Vieira; Franclim R Ribeiro; Maria J Soares; Rui Henrique; Jorge Oliveira; Carmen Jerónimo; Manuel Teixeira
Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2008;30(5):389-95.
2007: Rui Henrique; Vera L Costa; Carmen Jerónimo
Methylation-based biomarkers for early detection of urological cancer.
Critical reviews in oncogenesis 2007;13(4):265-82.
2007: Rui Henrique; Franclim R Ribeiro; Daniel Fonseca; Mohammad Hoque; André Lopes Carvalho; Vera L Costa; Mafalda Pinto; Jorge Oliveira; Manuel Teixeira; David Sidransky; Carmen Jerónimo
High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6122-9.
2007: Franclim R Ribeiro; Rui Henrique; Ana T Martins; Carmen Jerónimo; Manuel Teixeira
Relative copy number gain of MYC in diagnostic needle biopsies is an independent prognostic factor for prostate cancer patients.
European urology 2007;52(1):116-25.
2007: Mafalda Pinto; Maria J Soares; Nuno Cerveira; Rui Henrique; Franclim R Ribeiro; Jorge Oliveira; Carmen Jerónimo; Manuel Teixeira
Expression changes of the MAD mitotic checkpoint gene family in renal cell carcinomas characterized by numerical chromosome changes.
Virchows Archiv : an international journal of pathology 2007;450(4):379-85.
2007: Vera L Costa; Rui Henrique; Franclim R Ribeiro; Mafalda Pinto; Jorge Oliveira; Francisco Lobo; Manuel Teixeira; Carmen Jerónimo
Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors.
BMC cancer 2007;7():133.
2007: Vera L Costa; Rui Henrique; Carmen Jerónimo
Epigenetic markers for molecular detection of prostate cancer.
Disease markers 2007;23(1-2):31-41.
2006: Rui Henrique; Vera L Costa; Nuno Cerveira; André Lopes Carvalho; Mohammad Hoque; Franclim R Ribeiro; Jorge Oliveira; Manuel Teixeira; David Sidransky; Carmen Jerónimo
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Journal of molecular medicine (Berlin, Germany) 2006;84(11):911-8.
2006: Nuno Cerveira; Franclim R Ribeiro; Ana Peixoto; Vera Costa; Rui Henrique; Carmen Jerónimo; Manuel Teixeira
TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions.
Neoplasia (New York, N.Y.) 2006;8(10):826-32.
2006: André Lopes Carvalho; Alice Chuang; Wei-Wen Jiang; Juna Lee; Shahnaz Begum; Luana Poeta; Ming Zhao; Carmen Jerónimo; Rui Henrique; Chetan Nayak; Hannah Lui Park; Mariana Brait; Chunyan Liu; Shaoyu Zhou; Wayne M Koch; Vito Michele Fazio; Edward Ratovitski; Barry Trink; William H Westra; David Sidransky; Chulso Moon; Joseph A Califano
Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.
Cancer research 2006;66(19):9401-7.
2006: Franclim R Ribeiro; Carmen Jerónimo; Rui Henrique; Daniel Fonseca; Jorge Oliveira; Ragnhild A Lothe; Manuel Teixeira
8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):3961-70.
2006: Franclim R Ribeiro; Chieu B Diep; Carmen Jerónimo; Rui Henrique; Carlos Lopes; Mette Eknaes; Ole Christian Lingjaerde; Ragnhild A Lothe; Manuel Teixeira
Statistical dissection of genetic pathways involved in prostate carcinogenesis.
Genes, chromosomes & cancer 2006;45(2):154-63.
2006: Franclim R Ribeiro; Rui Henrique; Merete Hektoen; Marianne Berg; Carmen Jerónimo; Manuel Teixeira; Ragnhild A Lothe
Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas.
Molecular cancer 2006;5():33.
2006: Rui Henrique; Carmen Jerónimo; Manuel Teixeira; Mohammad Hoque; André Lopes Carvalho; Irene Pais; Franclim R Ribeiro; Jorge Oliveira; Carlos Lopes; David Sidransky
Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.
Molecular cancer research : MCR 2006;4(1):1-8.
2005: Joana Paredes; André Albergaria; João T Oliveira; Carmen Jerónimo; Fernanda Milanezi; Fernando C Schmitt
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):5869-77.
2005: Rui Henrique; Carmen Jerónimo; Mohammad Hoque; Shuji Nomoto; André Lopes Carvalho; Vera L Costa; Jorge Oliveira; Manuel Teixeira; Carlos Lopes; David Sidransky
MT1G hypermethylation is associated with higher tumor stage in prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1274-8.
2005: Carmen Jerónimo
Quantitative methylation profiling of renal tumors and the discovery of a new generation of molecular markers.
Future oncology (London, England) 2005;1(2):197-200.
2005: Rui Henrique; Carmen Jerónimo; Mohammad Hoque; André Lopes Carvalho; Jorge Oliveira; Manuel Teixeira; Carlos Lopes; David Sidransky
Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions.
DNA and cell biology 2005;24(4):264-9.
2004: Carmen Jerónimo; Rui Henrique; Mohammad Hoque; Elizabeth Mambo; Franclim R Ribeiro; Graça Varzim; Jorge Oliveira; Manuel Teixeira; Carlos Lopes; David Sidransky
A quantitative promoter methylation profile of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8472-8.
2004: Rui Henrique; Carmen Jerónimo
Molecular detection of prostate cancer: a role for GSTP1 hypermethylation.
European urology 2004;46(5):660-9; discussion 669.
2004: Carmen Jerónimo; Rui Henrique; Jorge Oliveira; F Lobo; I Pais; Manuel Teixeira; Carlos Lopes
Aberrant cellular retinol binding protein 1 (CRBP1) gene expression and promoter methylation in prostate cancer.
Journal of clinical pathology 2004;57(8):872-6.
2004: Carmen Jerónimo; Rui Henrique; Mohammad Hoque; Franclim R Ribeiro; Jorge Oliveira; Daniel Fonseca; Manuel Teixeira; Carlos Lopes; David Sidransky
Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4010-4.
2003: Yutaka Tokumaru; Shuji Nomoto; Carmen Jerónimo; Rui Henrique; Susan V Harden; Barry Trink; David Sidransky
Biallelic inactivation of the RIZ1 gene in human gastric cancer.
Oncogene 2003;22(44):6954-8.
2003: Carmen Jerónimo; Isabel Costa; M Conceição Martins; Paula Monteiro; Susana Lisboa; Carlos Palmeira; Rui Henrique; Manuel Teixeira; Carlos Lopes
Detection of gene promoter hypermethylation in fine needle washings from breast lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3413-7.
2003: Carmen Jerónimo; Rui Henrique; P F Campos; J Oliveira; O L Caballero; C Lopes; David Sidransky
Endothelin B receptor gene hypermethylation in prostate adenocarcinoma.
Journal of clinical pathology 2003;56(1):52-5.
2002: Carmen Jerónimo; Henning Usadel; Rui Henrique; Cristina Silva; Jorge Oliveira; Carlos Lopes; David Sidransky
Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer.
Urology 2002;60(6):1131-5.
2002: Carmen Jerónimo; Graça Varzim; Rui Henrique; Jorge Oliveira; Maria José Bento; Cristina Silva; Carlos Lopes; David Sidransky
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(5):445-50.
2002: Henning Usadel; Jan Brabender; Kathleen D Danenberg; Carmen Jerónimo; Susan V Harden; James M Engles; Peter V Danenberg; Stephen C Yang; David Sidransky
Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.
Cancer research 2002;62(2):371-5.
2001: Carmen Jerónimo; Henning Usadel; Rui Henrique; Jorge Oliveira; Carlos Lopes; William G Nelson; David Sidransky
Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma.
Journal of the National Cancer Institute 2001;93(22):1747-52.
2001: Carmen Jerónimo; Shuji Nomoto; Otavia L Caballero; Henning Usadel; Rui Henrique; Graça Varzim; Jorge Oliveira; Carlos Lopes; MS Fliss; David Sidransky
Mitochondrial mutations in early stage prostate cancer and bodily fluids.
Oncogene 2001;20(37):5195-8.
2001: MF Spafford; Wayne M Koch; AL Reed; Joseph A Califano; L H Xu; Claus F Eisenberger; L Yip; P L Leong; LI WU; S X Liu; Carmen Jerónimo; William H Westra; David Sidransky
Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):607-12.
2000: Rui Henrique; R Azevedo; Maria José Bento; J C Domingues; C Silva; Carmen Jerónimo
Prognostic value of Ki-67 expression in localized cutaneous malignant melanoma.
Journal of the American Academy of Dermatology 2000;43(6):991-1000.