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Derek Jewell

Research Profile

Disorders

Physiology

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Great Britain

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Chromosomes, Human, Pair 16

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Publications

TOP 3
J R Fraser Cummings; R M Cooney; G Clarke; John Beckly; A Geremia; saad pathan; Laura Hancock; Changcun Guo; Lon R Cardon; Derek P Jewell
The genetics of NOD-like receptors in Crohn's disease.
saad pathan; R E Gowdy; R Cooney; John Beckly; Laura Hancock; Changcun Guo; J C Barrett; A Morris; Derek P Jewell
Confirmation of the novel association at the BTNL2 locus with ulcerative colitis.
Rachel Cooney; J R Fraser Cummings; saad pathan; John Beckly; Alessandra Geremia; Laura Hancock; Changcun Guo; Andrew Morris; Derek P Jewell
Association between genetic variants in myosin IXB and Crohn's disease.

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All Publications

2010: J R Fraser Cummings; R M Cooney; G Clarke; John Beckly; A Geremia; saad pathan; Laura Hancock; Changcun Guo; Lon R Cardon; Derek P Jewell
The genetics of NOD-like receptors in Crohn's disease.
Tissue antigens 2010;76(1):48-56.
2009: saad pathan; R E Gowdy; R Cooney; John Beckly; Laura Hancock; Changcun Guo; J C Barrett; A Morris; Derek P Jewell
Confirmation of the novel association at the BTNL2 locus with ulcerative colitis.
Tissue antigens 2009;74(4):322-9.
2009: Rachel Cooney; J R Fraser Cummings; saad pathan; John Beckly; Alessandra Geremia; Laura Hancock; Changcun Guo; Andrew Morris; Derek P Jewell
Association between genetic variants in myosin IXB and Crohn's disease.
Inflammatory bowel diseases 2009;15(7):1014-21.
2009: Horace R T Williams; I Jane Cox; David G Walker; Bernard V North; Venisha M Patel; Sara E Marshall; Derek P Jewell; Subrata Ghosh; Huw J W Thomas; Julian Teare; Simon Jakobovits; Sebastian Zeki; Kenneth I Welsh; Simon D Taylor-Robinson; Timothy R Orchard
Characterization of inflammatory bowel disease with urinary metabolic profiling.
The American journal of gastroenterology 2009;104(6):1435-44.
2008: Harry J Thomas; Clare J Wotton; David Yeates; Tariq Ahmad; Derek P Jewell; Michael J Goldacre
Pneumococcal infection in patients with coeliac disease.
European journal of gastroenterology & hepatology 2008;20(7):624-8.
2008: John Beckly; Laura Hancock; Alessandra Geremia; J R Fraser Cummings; Andrew Morris; Rachel Cooney; saad pathan; Changcun Guo; Derek P Jewell
Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.
Inflammatory bowel diseases 2008;14(4):500-7.
2007: J R Fraser Cummings; Tariq Ahmad; Alessandra Geremia; John Beckly; Rachel Cooney; Laura Hancock; saad pathan; Changcun Guo; Lon R Cardon; Derek P Jewell
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.
Inflammatory bowel diseases 2007;13(9):1063-8.
2007: J R Fraser Cummings; Rachel Cooney; saad pathan; Carl A Anderson; Jeffrey C Barrett; John Beckly; Alessandra Geremia; Laura Hancock; Changcun Guo; Tariq Ahmad; Lon R Cardon; Derek P Jewell
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.
Inflammatory bowel diseases 2007;13(8):941-6.
2006: Dermot P B McGovern; Helen Butler; Tariq Ahmad; Marta Paolucci; David A van Heel; Kenichi Negoro; Pirro Hysi; Jiannis Ragoussis; S P L Travis; Lon R Cardon; Derek P Jewell
TUCAN (CARD8) genetic variants and inflammatory bowel disease.
Gastroenterology 2006;131(4):1190-6.
2006: Rosemary J Boyton; C Reynolds; Faisal Wahid; Meinir G Jones; L Ozerovitch; Tariq Ahmad; A Chaudhry; Derek P Jewell; Onn Min Kon; J Smith; Marlene Rose; Anthony Newman Taylor; P Cole; Robert Wilson; Daniel M Altmann
IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis.
Tissue antigens 2006;68(4):325-30.
2006: Des C Jones; R S Edgar; T Ahmad; J R Fraser Cummings; Derek P Jewell; John Trowsdale; Neil T Young
Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility.
Genes and immunity 2006;7(7):576-82.
2006: Karen A Hunt; Alienke J Monsuur; Wendy L McArdle; Parveen J Kumar; S P L Travis; Julian R F Walters; Derek P Jewell; D P Strachan; Raymond J Playford; Cisca Wijmenga; David A van Heel
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort.
Gut 2006;55(7):969-72.
2005: David A van Heel; Subrata Ghosh; Karen A Hunt; Christopher G Mathew; Alastair Forbes; Derek P Jewell; Raymond J Playford
Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.
Gut 2005;54(11):1553-7.
2005: Derek P Jewell; Jack Satsangi; Alan Lobo; Christopher Probert; Alastair Forbes; Subrata Ghosh; Jon Shaffer; Markus Frenz; Hazel Drummond; Gill Troy; Sue Turner; Lisa Younge; Lyn Evans; Mark Moosa; Barry Rodgers-Gray; Scot Buchan
Infliximab use in Crohn's disease: impact on health care resources in the UK.
European journal of gastroenterology & hepatology 2005;17(10):1047-52.
2005: Klaus R Herrlinger; J R Fraser Cummings; M C N M Barnardo; Matthias Schwab; Tariq Ahmad; Derek P Jewell
The pharmacogenetics of methotrexate in inflammatory bowel disease.
Pharmacogenetics and genomics 2005;15(10):705-11.
2005: Dermot P B McGovern; Derek P Jewell
Risks and benefits of azathioprine therapy.
Gut 2005;54(8):1055-9.
2005: David A van Heel; Subrata Ghosh; Matt Butler; Karen A Hunt; Anna M C Lundberg; Tariq Ahmad; Dermot P B McGovern; Clive M Onnie; Kenichi Negoro; Sue Goldthorpe; Brian M J Foxwell; Christopher G Mathew; Alastair Forbes; Derek P Jewell; Raymond J Playford
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease.
Lancet 2005;365(9473):1794-6.
2005: Dermot P B McGovern; Pirro Hysi; Tariq Ahmad; David A van Heel; Miriam F Moffatt; Alisoun Carey; William O C M Cookson; Derek P Jewell
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.
Human molecular genetics 2005;14(10):1245-50.
2005: Tariq Ahmad; L Zhang; F Gogus; David H Verity; G Wallace; Wafa Madanat; Faisal Fayyad; Teifi James; Matt J Neville; Charlie Kanawati; Farida Fortune; A Celik; M Stanford; Derek P Jewell; Sara E Marshall
CARD15 polymorphisms in Behçet's disease.
Scandinavian journal of rheumatology 2005;34(3):233-7.
2005: M Denise Robertson; Alex S T Bickerton; A L Dennis; Hubert Vidal; Derek P Jewell; Keith N Frayn
Enhanced metabolic cycling in subjects after colonic resection for ulcerative colitis.
The Journal of clinical endocrinology and metabolism 2005;90(5):2747-54.
2005: Karen A Hunt; Dermot P B McGovern; Parveen J Kumar; Subrata Ghosh; S P L Travis; Julian R F Walters; Derek P Jewell; Raymond J Playford; David A van Heel
A common CTLA4 haplotype associated with coeliac disease.
European journal of human genetics : EJHG 2005;13(4):440-4.
2005: J R Fraser Cummings; K R Herrlinger; S P L Travis; David A Gorard; Alistair S McIntyre; Derek P Jewell
Oral methotrexate in ulcerative colitis.
Alimentary pharmacology & therapeutics 2005;21(4):385-9.
2005: J R Fraser Cummings; Derek P Jewell
Clinical implications of inflammatory bowel disease genetics on phenotype.
Inflammatory bowel diseases 2005;11(1):56-61.
2004: Lee Min Yap; Tariq Ahmad; Derek P Jewell
The contribution of HLA genes to IBD susceptibility and phenotype.
Best practice & research. Clinical gastroenterology 2004;18(3):577-96.
2004: Jin Hong Low; Fiona A Williams; Xuesong Yang; Sue Cullen; James Colley; Khoon-Lin Ling; Alessandro Armuzzi; Tariq Ahmad; Matt J Neville; Bryan M Dechairo; Robert Walton; Nicholas J Lench; Derek P Jewell
Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1.
Inflammatory bowel diseases 2004;10(3):173-81.
2004: Xuesong Yang; Susan N Cullen; Jin H Li; Roger W Chapman; Derek P Jewell
Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1.
Journal of hepatology 2004;40(3):375-9.
2004: X Yang; Tariq Ahmad; F Gogus; David H Verity; Graham R Wallace; Wafa Madanat; Charlie Kanawati; Miles R Stanford; Farida Fortune; Derek P Jewell; Sara E Marshall
Analysis of the CC chemokine receptor 5 (CCR5) Delta32 polymorphism in Behçet's disease.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2004;31(1):11-4.
2003: Dermot P B McGovern; David A van Heel; Kenichi Negoro; Tariq Ahmad; Derek P Jewell
Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis.
American journal of human genetics 2003;73(6):1465-6.
2003: Tariq Ahmad; Alessandro Armuzzi; Matt J Neville; Mike Bunce; Khoon-Lin Ling; Ken I Welsh; Sara E Marshall; Derek P Jewell
The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis.
Tissue antigens 2003;62(6):527-35.
2003: David A van Heel; Bryan M Dechairo; Gary Dawson; Dermot P B McGovern; Kenichi Negoro; Alisoun Carey; Lon R Cardon; Ian Mackay; Derek P Jewell; Nicholas J Lench
The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.
Human molecular genetics 2003;12(20):2569-75.
2003: Alessandro Armuzzi; Tariq Ahmad; Khoon-Lin Ling; A de Silva; Sue Cullen; David A van Heel; Timothy R Orchard; Ken I Welsh; Sara E Marshall; Derek P Jewell
Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31.
Gut 2003;52(8):1133-9.
2003: M Denise Robertson; M Parkes; B F Warren; David J P Ferguson; Kim G Jackson; Derek P Jewell; Keith N Frayn
Mobilisation of enterocyte fat stores by oral glucose in humans.
Gut 2003;52(6):834-9.
2003: M Denise Robertson; Jenny M Currie; Linda M Morgan; Derek P Jewell; Keith N Frayn
Prior short-term consumption of resistant starch enhances postprandial insulin sensitivity in healthy subjects.
Diabetologia 2003;46(5):659-65.
2003: Kenichi Negoro; Dermot P B McGovern; Y Kinouchi; S Takahashi; Nicholas J Lench; T Shimosegawa; Alisoun Carey; Lon R Cardon; Derek P Jewell; David A van Heel
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.
Gut 2003;52(4):541-6.
2003: Tariq Ahmad; Matt J Neville; Sara E Marshall; Alessandro Armuzzi; Kim Mulcahy-Hawes; Jonathan Crawshaw; Hiroe Sato; Khoon-Lin Ling; M C N M Barnardo; Sue Goldthorpe; Robert Walton; Mike Bunce; Derek P Jewell; Ken I Welsh
Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC.
Human molecular genetics 2003;12(6):647-56.
2003: Tariq Ahmad; Graham R Wallace; Teifi James; Matt J Neville; Mike Bunce; Kim Mulcahy-Hawes; Alessandro Armuzzi; Jonathan Crawshaw; Farida Fortune; Robert Walton; Miles R Stanford; Ken I Welsh; Sara E Marshall; Derek P Jewell
Mapping the HLA association in Behçet's disease: a role for tumor necrosis factor polymorphisms?
Arthritis and rheumatism 2003;48(3):807-13.
2002: Timothy R Orchard; C N Chua; Tariq Ahmad; Hung Cheng; Ken I Welsh; Derek P Jewell
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes.
Gastroenterology 2002;123(3):714-8.
2002: David A van Heel; Dermot P B McGovern; Lon R Cardon; Bryan M Dechairo; Nicholas J Lench; Alisoun Carey; Derek P Jewell
Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.
American journal of medical genetics 2002;111(3):253-9.
2002: Tariq Ahmad; Sara E Marshall; Kim Mulcahy-Hawes; T Orchard; Jonathan Crawshaw; Alessandro Armuzzi; Matt J Neville; David A van Heel; M C N M Barnardo; Ken I Welsh; Derek P Jewell; Mike Bunce
High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility.
Tissue antigens 2002;60(2):164-79.
2002: David A van Heel; Irina A Udalova; Arjuna P De Silva; Dermot P B McGovern; Yoshitaka Kinouchi; Jeremy Hull; Nicholas J Lench; Lon R Cardon; Alisoun Carey; Derek P Jewell; Dominic Kwiatkowski
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors.
Human molecular genetics 2002;11(11):1281-9.
2002: Tariq Ahmad; Alessandro Armuzzi; Mike Bunce; Kim Mulcahy-Hawes; Sara E Marshall; Timothy R Orchard; Jonathan Crawshaw; Oliver Large; Arjuna de Silva; Julia T Cook; M C N M Barnardo; Sue Cullen; Ken I Welsh; Derek P Jewell
The molecular classification of the clinical manifestations of Crohn's disease.
Gastroenterology 2002;122(4):854-66.
2001: David A van Heel; Alisoun Carey; Derek P Jewell
Identification of novel polymorphisms in the beta7 integrin gene: family-based association studies in inflammatory bowel disease.
Genes and immunity 2001;2(8):455-60.
2001: Timothy R Orchard; A Dhar; J D Simmons; R Vaughan; Ken I Welsh; Derek P Jewell
MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathy.
Clinical and experimental immunology 2001;126(3):437-40.
2001: Dermot P B McGovern; David A van Heel; Tariq Ahmad; Derek P Jewell
NOD2 (CARD15), the first susceptibility gene for Crohn's disease.
Gut 2001;49(6):752-4.
2001: M Parkes; J Satsangi; Derek P Jewell; Daniel E Weeks; M. Michael Barmada; Richard H Duerr
Ulcerative colitis is more strongly linked to chromosome 12 than Crohn's disease.
Gut 2001;49(2):311.
2001: David A van Heel; Dermot P B McGovern; Derek P Jewell
Crohn's disease: genetic susceptibility, bacteria, and innate immunity.
Lancet 2001;357(9272):1902-4.
2000: M Parkes; M. Michael Barmada; J Satsangi; Daniel E Weeks; Derek P Jewell; Richard H Duerr
The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease.
American journal of human genetics 2000;67(6):1605-10.
2000: David A van Heel; M Allen; Derek P Jewell; Alisoun Carey
A revised sequence of the human beta7 integrin gene (ITGB7) promoter region obtained by inverse PCR.
Immunogenetics 2000;51(10):863-5.
2000: J D Simmons; Charles G Mullighan; Ken I Welsh; Derek P Jewell
Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.
Gut 2000;47(2):211-4.
2000: David A van Heel; Jack Satsangi; Alisoun Carey; Derek P Jewell
Inflammatory bowel disease: progress toward a gene.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000;14(3):207-18.
2000: Timothy R Orchard; S Thiyagaraja; Ken I Welsh; B P Wordsworth; J S Hill Gaston; Derek P Jewell
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease.
Gastroenterology 2000;118(2):274-8.
2000: Timothy R Orchard; J Satsangi; David A van Heel; Derek P Jewell
Genetics of inflammatory bowel disease: a reappraisal.
Scandinavian journal of immunology 2000;51(1):10-7.
1999: Timothy R Orchard; Derek P Jewell
The importance of ileocaecal integrity in the arthritic complications of Crohn's disease.
Inflammatory bowel diseases 1999;5(2):92-7.
1998: Timothy R Orchard; B P Wordsworth; Derek P Jewell
Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history.
Gut 1998;42(3):387-91.