FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Changhua Ji

Research Profile

Chemicals & Drugs

Concepts & Ideas

Living Beings

Anatomy

Procedures

Preclinical Drug Evaluations

Phenomena

Virus Internalization

Co-author Network

Publications

TOP 3
Changhua Ji; Patrick Kennedy; Klaus Klumpp; Erhard Kopetzki; Han Ma; Paul A MacAry; Stefan Ries; Surya Sankuratri; Konduru S R Sastry; Tenny Tang; Denise Teoh; Georg Tiefenthaler; Sandhya Bohini; Jennifer Cano; Antony Chen; Zi Zong Ho; Antonio Bertoletti
Targeted delivery of interferon-α to hepatitis B virus-infected cells using T-cell receptor-like antibodies.
Jürgen Schanzer; andreas jekle; Junichi Nezu; Adriane Lochner; Rebecca Croasdale; Marianna Dioszegi; Jun Zhang; Eike Hoffmann; Wilma Dormeyer; Jan Stracke; Wolfgang Schäfer; Changhua Ji; Gabrielle Heilek; Nick Cammack; Michael Brandt; Pablo Umana; Ulrich Brinkmann
Development of tetravalent, bispecific CCR5 antibodies with antiviral activity against CCR5 monoclonal antibody-resistant HIV-1 strains.
Jutta Wanner; Lijing Chen; Rémy C Lemoine; Rama Kondru; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; Pamela W Berry; David M Rotstein
Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Changhua Ji (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Changhua Ji; Patrick Kennedy; Klaus Klumpp; Erhard Kopetzki; Han Ma; Paul A MacAry; Stefan Ries; Surya Sankuratri; Konduru S R Sastry; Tenny Tang; Denise Teoh; Georg Tiefenthaler; Sandhya Bohini; Jennifer Cano; Antony Chen; Zi Zong Ho; Antonio Bertoletti
Targeted delivery of interferon-α to hepatitis B virus-infected cells using T-cell receptor-like antibodies.
Hepatology (Baltimore, Md.) 2012;56(6):2027-38.
2011: Jürgen Schanzer; andreas jekle; Junichi Nezu; Adriane Lochner; Rebecca Croasdale; Marianna Dioszegi; Jun Zhang; Eike Hoffmann; Wilma Dormeyer; Jan Stracke; Wolfgang Schäfer; Changhua Ji; Gabrielle Heilek; Nick Cammack; Michael Brandt; Pablo Umana; Ulrich Brinkmann
Development of tetravalent, bispecific CCR5 antibodies with antiviral activity against CCR5 monoclonal antibody-resistant HIV-1 strains.
Antimicrobial agents and chemotherapy 2011;55(5):2369-78.
2010: Jutta Wanner; Lijing Chen; Rémy C Lemoine; Rama Kondru; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; Pamela W Berry; David M Rotstein
Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series.
Bioorganic & medicinal chemistry letters 2010;20(22):6802-7.
2010: Rémy C Lemoine; Ann C Petersen; Lina Setti; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; Pamela Berry; David M Rotstein
Exploration of a new series of CCR5 antagonists: multi-dimensional optimization of a sub-series containing N-substituted pyrazoles.
Bioorganic & medicinal chemistry letters 2010;20(16):4753-6.
2010: David M Rotstein; Stephen D Gabriel; Nicole Manser; Lubov Filonova; Fernando Padilla; Surya Sankuratri; Changhua Ji; Andre deRosier; Marianna Dioszegi; Gabrielle Heilek; andreas jekle; Paul Weller; Pamela Berry
Synthesis, SAR and evaluation of [1,4']-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists.
Bioorganic & medicinal chemistry letters 2010;20(11):3219-22.
2010: David M Rotstein; Chris R Melville; Fernando Padilla; Dick Cournoyer; Eun K Lee; Remy Lemoine; Ann C Petersen; Lina Q Setti; Jutta Wanner; Lijing Chen; Lubov Filonova; David G Loughhead; Jason Manka; Xiao-Fa Lin; Shelley Gleason; Surya Sankuratri; Changhua Ji; Andre Derosier; Marianna Dioszegi; Gabrielle Heilek; andreas jekle; Pamela Berry; Cheng-I Mau; Paul Weller
Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
Bioorganic & medicinal chemistry letters 2010;20(10):3116-9.
2010: Rémy C Lemoine; Ann C Petersen; Lina Setti; Lijing Chen; Jutta Wanner; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; David M Rotstein
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists.
Bioorganic & medicinal chemistry letters 2010;20(6):1830-3.
2010: Rémy C Lemoine; Ann C Petersen; Lina Setti; Thomas Baldinger; Jutta Wanner; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; David M Rotstein
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc.
Bioorganic & medicinal chemistry letters 2010;20(5):1674-6.
2010: Rémy C Lemoine; Ann C Petersen; Lina Setti; Jutta Wanner; andreas jekle; Gabrielle Heilek; André deRosier; Changhua Ji; Pamela Berry; David Rotstein
Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycles.
Bioorganic & medicinal chemistry letters 2010;20(2):704-8.
2009: David M Rotstein; Stephen D Gabriel; Ferenc Makra; Lubov Filonova; Shelley Gleason; Christine Brotherton-Pleiss; Lina Q Setti; Alejandra Trejo-Martin; Eun Kyung Lee; Surya Sankuratri; Changhua Ji; Andre Derosier; Marianna Dioszegi; Gabrielle Heilek; andreas jekle; Pamela Berry; Paul Weller; Cheng-I Mau
Spiropiperidine CCR5 antagonists.
Bioorganic & medicinal chemistry letters 2009;19(18):5401-6.
2009: andreas jekle; Eugene Chow; Erhard Kopetzki; Changhua Ji; Mei Jun Yan; Rosa Nguyen; Surya Sankuratri; Nick Cammack; Gabrielle Heilek
CD4-BFFI: a novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency.
Antiviral research 2009;83(3):257-66.
2009: Changhua Ji; Erhard Kopetzki; andreas jekle; Kay-Gunnar Stubenrauch; Xingrong Liu; Jun Zhang; Eileen Rao; Tilman Schlothauer; Stephan Fischer; Nick Cammack; Gabrielle Heilek; Stefan Ries; Surya Sankuratri
CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability.
The Journal of biological chemistry 2009;284(8):5175-85.
2009: Hanbiao Yang; Xiao-Fa Lin; Fernando Padilla; Stephen D Gabriel; Gabrielle Heilek; Changhua Ji; Surya Sankuratri; André deRosier; Pamela Berry; David M Rotstein
Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist.
Bioorganic & medicinal chemistry letters 2009;19(1):209-13.
2008: Rama Kondru; Jun Zhang; Changhua Ji; Tara Mirzadegan; David Rotstein; Surya Sankuratri; Marianna Dioszegi
Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists.
Molecular pharmacology 2008;73(3):789-800.
2008: Erhard Kopetzki; andreas jekle; Changhua Ji; Eileen Rao; Jun Zhang; Stephan Fischer; Nick Cammack; Surya Sankuratri; Gabrielle Heilek
Closing two doors of viral entry: intramolecular combination of a coreceptor- and fusion inhibitor of HIV-1.
Virology journal 2008;5():56.
2007: Changhua Ji; Jun Zhang; Marianna Dioszegi; Sophie Chiu; Eileen Rao; Andre Derosier; Nick Cammack; Michael Brandt; Surya Sankuratri
CCR5 small-molecule antagonists and monoclonal antibodies exert potent synergistic antiviral effects by cobinding to the receptor.
Molecular pharmacology 2007;72(1):18-28.
2007: Changhua Ji; Michael Brandt; Marianna Dioszegi; andreas jekle; Stephan Schwoerer; Steven Challand; Jun Zhang; Yun Chen; Lisa Zautke; Gunthar Achhammer; Monika Baehner; Sandra Kroetz; Gabrielle Heilek-Snyder; Ralf Schumacher; Nick Cammack; Surya Sankuratri
Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities.
Antiviral research 2007;74(2):125-37.
2007: Jun Zhang; Eileen Rao; Marianna Dioszegi; Rama Kondru; Andre Derosier; Eva Chan; Stephan Schwoerer; Nick Cammack; Michael Brandt; Surya Sankuratri; Changhua Ji
The second extracellular loop of CCR5 contains the dominant epitopes for highly potent anti-human immunodeficiency virus monoclonal antibodies.
Antimicrobial agents and chemotherapy 2007;51(4):1386-97.
2006: Eva Chan; Gabrielle Heilek-Snyder; Nick Cammack; Surya Sankuratri; Changhua Ji
Development of a Moloney murine leukemia virus-based pseudotype anti-HIV assay suitable for accurate and rapid evaluation of HIV entry inhibitors.
Journal of biomolecular screening 2006;11(6):652-63.
2006: Changhua Ji; Jun Zhang; Nick Cammack; Surya Sankuratri
Development of a novel dual CCR5-dependent and CXCR4-dependent cell-cell fusion assay system with inducible gp160 expression.
Journal of biomolecular screening 2006;11(1):65-74.