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Yong-Hua Ji

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TOP 3
Jie Tao; Zhi-Rui Liu; Jian Shi; Yong-Hua Ji
Martentoxin: a unique ligand of BK channels.
Zhi-Rui Liu; Jie Tao; Zhi-Jun Cheng; Gang Ding; Bang-Qian Dong; Hui-Qiong He; Yong-Hua Ji
Pharmacological kinetics of BmK AS, a sodium channel site 4-specific modulator on Nav1.3.
Zhi-Rui Liu; Pin Ye; Yong-Hua Ji
Exploring the obscure profiles of pharmacological binding sites on voltage-gated sodium channels by BmK neurotoxins.

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2012: Jie Tao; Zhi-Rui Liu; Jian Shi; Yong-Hua Ji
Martentoxin: a unique ligand of BK channels.
Sheng li xue bao : [Acta physiologica Sinica] 2012;64(4):355-64.
2012: Zhi-Rui Liu; Jie Tao; Zhi-Jun Cheng; Gang Ding; Bang-Qian Dong; Hui-Qiong He; Yong-Hua Ji
Pharmacological kinetics of BmK AS, a sodium channel site 4-specific modulator on Nav1.3.
Neuroscience bulletin 2012;28(3):209-21.
2011: Zhi-Rui Liu; Pin Ye; Yong-Hua Ji
Exploring the obscure profiles of pharmacological binding sites on voltage-gated sodium channels by BmK neurotoxins.
Protein & cell 2011;2(6):437-44.
2011: Rong Zhao; Chun-Chun Weng; Qi Feng; Lulan Chen; Xu-Ying Zhang; Hong-Yan Zhu; Yun Wang; Yong-Hua Ji
Anticonvulsant activity of BmK AS, a sodium channel site 4-specific modulator.
Epilepsy & behavior : E&B 2011;20(2):267-76.
2010: Zhan-Tao Bai; Tong Liu; Feng Jiang; Ming Cheng; Xue-Yan Pang; Li-Ming Hua; Jian Shi; Jing-Jing Zhou; Xue-Qin Shu; Jian-Wei Zhang; Yong-Hua Ji
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
Experimental neurology 2010;226(1):159-72.
2010: Hui-Wen Cheng; Hong-Tian Yang; Jing-Jing Zhou; Yong-Hua Ji; Hong-Yan Zhu
Pharmacological modulation of brain Nav1.2 and cardiac Nav1.5 subtypes by the local anesthetic ropivacaine.
Neuroscience bulletin 2010;26(4):289-96.
2009: Mang-Mang Zhu; Jie Tao; Miao Tan; Hong-Tian Yang; Yong-Hua Ji
U-shaped dose-dependent effects of BmK AS, a unique scorpion polypeptide toxin, on voltage-gated sodium channels.
British journal of pharmacology 2009;158(8):1895-903.
2009: Feng Jiang; Tong Liu; Ming Cheng; Xue-Yan Pang; Zhan-Tao Bai; Jing-Jing Zhou; Yong-Hua Ji
Spinal astrocyte and microglial activation contributes to rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karch.
European journal of pharmacology 2009;623(1-3):52-64.
2009: Ying Liu; Zhan-Tao Bai; Xing-Hua Feng; Wen-Peng Li; Hong-Tian Yang; Jing-Jing Zhou; Yong-Hua Ji
Hyper-excitability in low threshold mechanical A fibers is potentially involved in scorpion BmK sting pain.
Brain research bulletin 2009;80(3):116-21.
2009: Mang-Mang Zhu; Miao Tan; Hui-Wen Cheng; Yong-Hua Ji
The alpha-like scorpion toxin BmK I enhances membrane excitability via persistent sodium current by preventing slow inactivation and deactivation of rNav1.2a expressed in Xenopus Oocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(4):561-8.
2008: Zhan-Tao Bai; Tong Liu; Xue-Yan Pang; Feng Jiang; Ming Cheng; Yong-Hua Ji
Functional depletion of capsaicin-sensitive primary afferent fibers attenuates rat pain-related behaviors and paw edema induced by the venom of scorpion Buthus martensi Karch.
Neuroscience research 2008;62(2):78-85.
2008: Xing-Hua Feng; Jue-Xu Chen; Ying Liu; Yong-Hua Ji
Electrophysiological characterization of BmK I, an alpha-like scorpion toxin, on rNav1.5 expressed in HEK293t cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(6):1582-7.
2008: Tong Liu; Xue-Yan Pang; Feng Jiang; Yong-Hua Ji
Involvement of spinal nitric oxide (NO) in rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.
Toxicon : official journal of the International Society on Toxinology 2008;52(1):62-71.
2008: Tong Liu; Xue-Yan Pang; Feng Jiang; Zhan-Tao Bai; Yong-Hua Ji
Anti-nociceptive effects induced by intrathecal injection of BmK AS, a polypeptide from the venom of Chinese-scorpion Buthus martensi Karsch, in rat formalin test.
Journal of ethnopharmacology 2008;117(2):332-8.
2008: Jian Shi; Hui Qiong He; Rong Zhao; Yan-Hong Duan; Jin Chen; Ying Chen; Juan Yang; Jian Wei Zhang; Xue Qin Shu; Ping Zheng; Yong-Hua Ji
Inhibition of martentoxin on neuronal BK channel subtype (alpha+beta4): implications for a novel interaction model.
Biophysical journal 2008;94(9):3706-13.
2008: Miao Tan; Mang-Mang Zhu; Ying Liu; Hui-Wen Cheng; Yong-Hua Ji
Effects of BmK AS on Nav1.2 expressed in Xenopus laevis oocytes.
Cell biology and toxicology 2008;24(2):143-9.
2007: Tong Liu; Xue-Yan Pang; Zhan-Tao Bai; Zhi-Fang Chai; Feng Jiang; Yong-Hua Ji
Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.
Toxicon : official journal of the International Society on Toxinology 2007;50(8):1073-84.
2007: Tong Liu; Zhan-Tao Bai; Xue-Yan Pang; Zhi-Fang Chai; Feng Jiang; Yong-Hua Ji
Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom.
European journal of pharmacology 2007;575(1-3):46-56.
2007: Zhan-Tao Bai; Tong Liu; Xue-Yan Pang; Zhi-Fang Chai; Yong-Hua Ji
Suppression by intrathecal BmK IT2 on rat spontaneous pain behaviors and spinal c-Fos expression induced by formalin.
Brain research bulletin 2007;73(4-6):248-53.
2007: Zhi-Fang Chai; Zhan-Tao Bai; Xu-Ying Zhang; Tong Liu; Xue-Yan Pang; Yong-Hua Ji
Rat epileptic seizures evoked by BmK alphaIV and its possible mechanisms involved in sodium channels.
Toxicology and applied pharmacology 2007;220(3):235-42.
2006: Zhan-Tao Bai; Tong Liu; Zhi-Fang Chai; Xue-Yan Pang; Yong-Hua Ji
Rat pain-related responses induced by experimental scorpion BmK sting.
European journal of pharmacology 2006;552(1-3):67-77.
2006: Zhi-Fang Chai; Mang-Mang Zhu; Zhan-Tao Bai; Tong Liu; Miao Tan; Xue-Yan Pang; Yong-Hua Ji
Chinese-scorpion (Buthus martensi Karsch) toxin BmK alphaIV, a novel modulator of sodium channels: from genomic organization to functional analysis.
The Biochemical journal 2006;399(3):445-53.
2006: Jin Chen; Xing-Hua Feng; Jian Shi; Zhi-Yong Tan; Zhan-Tao Bai; Tong Liu; Yong-Hua Ji
The anti-nociceptive effect of BmK AS, a scorpion active polypeptide, and the possible mechanism on specifically modulating voltage-gated Na+ currents in primary afferent neurons.
Peptides 2006;27(9):2182-92.
2006: Xiao-Pan Zuo; Hui-Qiong He; Ming He; Zhi-Rui Liu; Qing Xu; Jian-Guo Ye; Yong-Hua Ji
Comparative pharmacology and cloning of two novel arachnid sodium channels: Exploring the adaptive insensitivity of scorpion to its toxins.
FEBS letters 2006;580(18):4508-14.
2006: Zhi-Fang Chai; Zhan-Tao Bai; Tong Liu; Xue-Yan Pang; Yong-Hua Ji
The binding of BmK IT2 on mammal and insect sodium channels by surface plasmon resonance assay.
Pharmacological research : the official journal of the Italian Pharmacological Society 2006;54(2):85-90.
2006: Zhan-Tao Bai; Rong Zhao; Xu-Ying Zhang; Jin Chen; Tong Liu; Yong-Hua Ji
The epileptic seizures induced by BmK I, a modulator of sodium channels.
Experimental neurology 2006;197(1):167-76.
2005: Jin Chen; Zhi-Yong Tan; Rong Zhao; Xing-Hua Feng; Jian Shi; Yong-Hua Ji
The modulation effects of BmK I, an alpha-like scorpion neurotoxin, on voltage-gated Na(+) currents in rat dorsal root ganglion neurons.
Neuroscience letters 2005;390(2):66-71.
2005: Wei-Xi Wang; Yong-Hua Ji
Scorpion venom induces glioma cell apoptosis in vivo and inhibits glioma tumor growth in vitro.
Journal of neuro-oncology 2005;73(1):1-7.
2005: Hai-Ying Sun; Zhao-Nian Zhou; Yong-Hua Ji
The role of voltage-gated Na+ channels in excitation-contraction coupling of rat heart determined by BmK I, an alpha-like scorpion neurotoxin.
Toxicology in vitro : an international journal published in association with BIBRA 2005;19(2):183-90.
2004: Xiao-Pan Zuo; Yong-Hua Ji
Molecular mechanism of scorpion neurotoxins acting on sodium channels: insight into their diverse selectivity.
Molecular neurobiology 2004;30(3):265-78.
2004: Peng Qiao; Xiao-Pan Zuo; Zhi-Fang Chai; Yong-Hua Ji
The cDNA and genomic DNA organization of a novel toxin SHT-I from spider Ornithoctonus huwena.
Acta biochimica et biophysica Sinica 2004;36(10):656-60.
2004: Yong-Hua Ji; Hai Ying Sun
[Cardiac excitation-contraction coupling mediated by Ca2+].
Shi yan sheng wu xue bao 2004;37(1):78-83.
2004: Zhi-Yong Tan; Jin Chen; Xing-Hua Feng; Terakawa Susumu; Yong-Hua Ji
Modulation of intracellular Na+ concentration by BmK AS, a scorpion toxin, in B104 cell line.
Neuroreport 2004;15(1):13-6.
2003: Hai-Ying Sun; Hai-Feng Zhu; Yong-Hua Ji
BmK I, an alpha-like scorpion neurotoxin, specifically modulates isolated rat cardiac mechanical and electrical activity.
Sheng li xue bao : [Acta physiologica Sinica] 2003;55(5):530-4.
2003: Zhan-Tao Bai; Xu-Ying Zhang; Yong-Hua Ji
Fos expression in rat spinal cord induced by peripheral injection of BmK I, an alpha-like scorpion neurotoxin.
Toxicology and applied pharmacology 2003;192(1):78-85.
2003: Xu-Ying Zhang; Zhan-Tao Bai; Zhi-Fang Chai; Jian-Wei Zhang; Ying Liu; Yong-Hua Ji
Suppressive effects of BmK IT2 on nociceptive behavior and c-Fos expression in spinal cord induced by formalin.
Journal of neuroscience research 2003;74(1):167-73.
2003: Zhi-Yong Tan; Jin Chen; Hai-Ying Shun; Xing-Hua Feng; Yong-Hua Ji
Modulation of BmK AS, a scorpion neurotoxic polypeptide, on voltage-gated Na+ channels in B104 neuronal cell line.
Neuroscience letters 2003;340(2):123-6.
2003: Yong-Hua Ji; Wei-Xi Wang; Jian-Guo Ye; Lin-Lin He; Ya-Jun Li; Yan-Ping Yan; Zhuan Zhou
Martentoxin, a novel K+-channel-blocking peptide: purification, cDNA and genomic cloning, and electrophysiological and pharmacological characterization.
Journal of neurochemistry 2003;84(2):325-35.
2002: Zhan-Tao Bai; Bing Chen; Xu-Ying Zhang; Guang-Li Fan; Yong-Hua Ji
c-Fos expression in rat spinal cord induced by scorpion BmK venom via plantar subcutaneous injection.
Neuroscience research 2002;44(4):447-54.
2002: Yong-Hua Ji; Wei-Xi Wang; Qiong Wang; Yong-Ping Huang
The binding of BmK abT, a unique neurotoxin, to mammal brain and insect Na(+) channels using biosensor.
European journal of pharmacology 2002;454(1):25-30.
2002: Xu-Ying Zhang; Jian-Wei Zhang; Bing Chen; Zhan-Tao Bai; Jun Shen; Yong-Hua Ji
Dynamic determination and possible mechanism of amino acid transmitter release from rat spinal dorsal horn induced by the venom and a neurotoxin (BmK I) of scorpion Buthus martensi Karsch.
Brain research bulletin 2002;58(1):27-31.
2001: Y Wu; Yong-Hua Ji; Y L Shi
Sodium current in NG108-15 cell inhibited by scorpion toxin BmKAS-1 and restored by its specific monoclonal antibodies.
Journal of natural toxins 2001;10(3):193-8.
2001: Jian-Guo Ye; Jiangye Chen; Xiao-Pan Zuo; Yong-Hua Ji
Cloning and characterization of cDNA sequences encoding two novel alpha-like-toxin precursors from the Chinese scorpion Buthus martensii Karsch.
Toxicon : official journal of the International Society on Toxinology 2001;39(8):1191-4.
2001: Zhi-Yong Tan; H Xiao; X Mao; CY Wang; Zhi-Qi Zhao; Yong-Hua Ji
The inhibitory effects of BmK IT2, a scorpion neurotoxin on rat nociceptive flexion reflex and a possible mechanism for modulating voltage-gated Na(+) channels.
Neuropharmacology 2001;40(3):352-7.
2001: Zhi-Yong Tan; X Mao; H Xiao; Zhi-Qi Zhao; Yong-Hua Ji
Buthus martensi Karsch agonist of skeletal-muscle RyR-1, a scorpion active polypeptide: antinociceptive effect on rat peripheral nervous system and spinal cord, and inhibition of voltage-gated Na(+) currents in dorsal root ganglion neurons.
Neuroscience letters 2001;297(2):65-8.
2000: Ya-Jun Li; Zhi-Yong Tan; Yong-Hua Ji
The binding of BmK IT2, a depressant insect-selective scorpion toxin on mammal and insect sodium channels.
Neuroscience research 2000;38(3):257-64.
2000: CY Wang; Zhi-Yong Tan; Bing Chen; Zhi-Qi Zhao; Yong-Hua Ji
Antihyperalgesia effect of BmK IT2, a depressant insect-selective scorpion toxin in rat by peripheral administration.
Brain research bulletin 2000;53(3):335-8.
2000: Ya-Jun Li; Yong-Hua Ji
Binding characteristics of BmK I, an alpha-like scorpion neurotoxic polypeptide, on cockroach nerve cord synaptosomes.
The journal of peptide research : official journal of the American Peptide Society 2000;56(4):195-200.
2000: Ya-Jun Li; Y Liu; Yong-Hua Ji
BmK AS: new scorpion neurotoxin binds to distinct receptor sites of mammal and insect voltage-gated sodium channels.
Journal of neuroscience research 2000;61(5):541-8.
2000: Jian-Guo Ye; CY Wang; Ya-Jun Li; Zhi-Yong Tan; Y P Yan; C Li; Jiangye Chen; Yong-Hua Ji
Purification, cDNA cloning and function assessment of BmK abT, a unique component from the Old World scorpion species.
FEBS letters 2000;479(3):136-40.
2000: Q C Tong; Yingmin Zhang; D P Li; Zhao-Nian Zhou; Yong-Hua Ji
The blocking effect of BmP02, one novel short-chain scorpion peptide on transient outward K(+) channel of adult rat ventricular myocyte.
Regulatory peptides 2000;90(1-3):85-92.
2000: LY Jia; H F Xie; Yong-Hua Ji
Characterization of four distinct monoclonal antibodies specific to BmK AS-1, a novel scorpion bioactive polypeptide.
Toxicon : official journal of the International Society on Toxinology 2000;38(5):605-17.
1999: LY Jia; Jian-Wei Zhang; Yong-Hua Ji
Biosensor binding assay of BmK AS-1, a novel Na+ channel-blocking scorpion ligand on rat brain synaptosomes.
Neuroreport 1999;10(16):3359-62.
1999: Y J Li; Yong-Hua Ji
[Channelopathy of voltage-gated sodium channel].
Sheng li ke xue jin zhan [Progress in physiology] 1999;30(4):297-302.
1999: Zhi-Yong Tan; Yong-Hua Ji
[Voltage-gated Na+ channel in nociceptive afferents of DRG neurons].
Sheng li ke xue jin zhan [Progress in physiology] 1999;30(3):198-202.
1999: LY Jia; Yong-Hua Ji
[Subtypes and functions of voltage-gated Na+ channel].
Sheng li ke xue jin zhan [Progress in physiology] 1999;30(2):107-12.
1999: Yong-Hua Ji; Ya-Jun Li; Jian-Wei Zhang; B L Song; T Yamaki; T Mochizuki; M Hoshino; N Yanaihara
Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch.
Toxicon : official journal of the International Society on Toxinology 1999;37(3):519-36.
1996: Yong-Hua Ji; Pascal Mansuelle; Susumu Terakawa; Charles Kopeyan; N Yanaihara; K Hsu; Hervé Rochat
Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity.
Toxicon : official journal of the International Society on Toxinology 1996;34(9):987-1001.
1994: Yong-Hua Ji; H Hattori; K Xu; Susumu Terakawa
Molecular characteristics of four new depressant insect neurotoxins purified from venom of Buthus martensi Karsch by HPLC.
Science in China. Series B, Chemistry, life sciences & earth sciences 1994;37(8):955-63.
1994: Yong-Hua Ji; Pascal Mansuelle; K Xu; Claude Granier; Charles Kopeyan; Susumu Terakawa; Hervé Rochat
Amino acid sequence of an excitatory insect-selective toxin (BmK IT) from venom of the scorpion Buthus martensi Karsch.
Science in China. Series B, Chemistry, life sciences & earth sciences 1994;37(1):42-9.
1993: Pascale Marchot; A Khélif; Yong-Hua Ji; Pascal Mansuelle; Pierre E Bougis
Binding of 125I-fasciculin to rat brain acetylcholinesterase. The complex still binds diisopropyl fluorophosphate.
The Journal of biological chemistry 1993;268(17):12458-67.
1989: Susumu Terakawa; Y Kimura; K Hsu; Yong-Hua Ji
Lack of effect of a neurotoxin from the scorpion Buthus martensi Karsch on nerve fibers of this scorpion.
Toxicon : official journal of the International Society on Toxinology 1989;27(5):569-78.
1988: Yong-Hua Ji; Y Kimura; K Hsu; Susumu Terakawa
Purification and the partial amino acid sequence of an insect neurotoxin from the venom of scorpion Buthus martensi Karsch.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1988;90(1):237-40.