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Bing-Hua Jiang

Research Profile

Chemicals & Drugs

Physiology

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Xu Qian; Zhu-Mei Shi; Lin Wang; Qing Xu; Yu Yin; Jing Yu; Lou-Qian Zhang; Li-Hui Lai; Chong-Yong Li; Qi Li; Wei Li; Ling-Zhi Liu; Jun He; Bing-Hua Jiang
MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.
Bing-Hua Jiang
Editorial (Hot Topic: PI3K/AKT and mTOR/p70S6K1 Signaling Pathways in Human Cancer).
Faton Agani; Bing-Hua Jiang
Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer.

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2013: Xu Qian; Zhu-Mei Shi; Lin Wang; Qing Xu; Yu Yin; Jing Yu; Lou-Qian Zhang; Li-Hui Lai; Chong-Yong Li; Qi Li; Wei Li; Ling-Zhi Liu; Jun He; Bing-Hua Jiang
MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.
Cell cycle (Georgetown, Tex.) 2013;12(9):1385-94.
2013: Bing-Hua Jiang
Editorial (Hot Topic: PI3K/AKT and mTOR/p70S6K1 Signaling Pathways in Human Cancer).
Current cancer drug targets 2013;13(3):233.
2013: Faton Agani; Bing-Hua Jiang
Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer.
Current cancer drug targets 2013;13(3):245-51.
2013: Richard L Carpenter; Bing-Hua Jiang
Roles of EGFR, PI3K, AKT, and mTOR in Heavy Metal-Induced Cancer.
Current cancer drug targets 2013;13(3):252-66.
2013: Qing Xu; Yu Yin; Jun He; Bing-Hua Jiang; Yue Jiang; Yi Jing; Qi Li; Wei Li; Bo Lu; Stephen S Peiper; Yan-Ting Qi; Qian Xu; Ling-Zhi Liu
A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1.
Journal of molecular cell biology 2013;5(1):3-13.
2013: Jun He; Bing-Hua Jiang; Yi Jing; Feng-Shan Li; Wei Li; Ling-Zhi Liu; Xu Qian; Qing Xu; Yue Jiang
Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis.
PloS one 2013;8(2):e56647.
2012: Jun He; Faton Agani; Richard Carpenter; Yi Jing; Qi Li; Ling-Zhi Liu; Zhimin Lu; Stephen S Peiper; Xu Qian; Xin-Ru Wang; Qing Xu; Bing-Hua Jiang
Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation.
EMBO reports 2012;13(12):1116-22.
2012: Jun He; Chongyong Li; Ling-Zhi Liu; Xu Qian; Zhumei Shi; Min Wang; Qing Xu; Bing-Hua Jiang
Oral Administration of Apigenin Inhibits Metastasis through AKT/P70S6K1/MMP-9 Pathway in Orthotopic Ovarian Tumor Model.
International journal of molecular sciences 2012;13(6):7271-82.
2012: Djordje Medan; Liying Wang; Neelam Azad; John B Barnett; Mary E Davis; Lan Guo; Bing-Hua Jiang; Sudjit Luanpitpong; Yon Rojanasakul
Multifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cells.
PloS one 2012;7(5):e37045.
2012: Zhu-mei Shi; Jing Wang; Xie-feng Wang; Ying-ying Wang; Zhiping Yan; Yu Yin; Yong-ping You; Peng Zhao; Chong-yong Li; Ming-na Li; Ling-Zhi Liu; Ning Liu; Xu Qian; Bing-Hua Jiang
MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1.
PloS one 2012;7(3):e32709.
2011: Zainab Abu Deeb; Donald A Adjeroh; Bing-Hua Jiang
Protein surface characterization using an invariant descriptor.
International journal of biomedical imaging 2011;2011():918978.
2011: Ling-Zhi Liu; Chongyong Li; Qi Chen; Yi Jing; Richard Carpenter; Yue Jiang; Hsiang-Fu Kung; Lihui Lai; Bing-Hua Jiang
MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression.
PloS one 2011;6(4):e19139.
2010: Chuan-Xiu Bian; Zhumei Shi; Qiao Meng; Yue Jiang; Ling-Zhi Liu; Bing-Hua Jiang
P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expression.
Biochemical and biophysical research communications 2010;398(3):395-9.
2010: Peng Zhao; Qiao Meng; Ling-Zhi Liu; You-Ping You; Ning Liu; Bing-Hua Jiang
Regulation of survivin by PI3K/Akt/p70S6K1 pathway.
Biochemical and biophysical research communications 2010;395(2):219-24.
2010: Yongju Lu; Neelam Azad; Liying Wang; Anand K V Iyer; Vincent Castranova; Bing-Hua Jiang; Yon Rojanasakul
Phosphatidylinositol-3-kinase/akt regulates bleomycin-induced fibroblast proliferation and collagen production.
American journal of respiratory cell and molecular biology 2010;42(4):432-41.
2010: Haitao Luo; Matthew K Daddysman; Gary O Rankin; Bing-Hua Jiang; Yi C Chen
Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc.
Cancer cell international 2010;10():16.
2009: Min Ding; Elena R Kisin; J Zhao; Linda Bowman; Yongju Lu; Bing-Hua Jiang; S Leonard; Val Vallyathan; Vincent Castranova; Ashley R Murray; B Fadeel; Anna A Shvedova
Size-dependent effects of tungsten carbide-cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells.
Toxicology and applied pharmacology 2009;241(3):260-8.
2009: Pithi Chanvorachote; Ubonthip Nimmannit; Yongju Lu; Siera Talbott; Bing-Hua Jiang; Yon Rojanasakul
Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1.
The Journal of biological chemistry 2009;284(41):28476-84.
2009: Bing-Hua Jiang; Ling-Zhi Liu
PI3K/PTEN signaling in angiogenesis and tumorigenesis.
Advances in cancer research 2009;102():19-65.
2009: Jinshun Zhao; Linda Bowman; Xingdong Zhang; Xianglin Shi; Bing-Hua Jiang; Vincent Castranova; Min Ding
Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway.
Journal of nanobiotechnology 2009;7():2.
2009: Yue Jiang; Bojan Cukic; Donald A Adjeroh; Heath Devin Skinner; Jie Lin; Qingxi J Shen; Bing-Hua Jiang
An algorithm for identifying novel targets of transcription factor families: application to hypoxia-inducible factor 1 targets.
Cancer informatics 2009;7():75-89.
2008: Ling-Zhi Liu; Jenny Z Zheng; Xin-Ru Wang; Bing-Hua Jiang
Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis.
Cancer research 2008;68(19):8183-8.
2008: Hua Yao; Huiming Wang; Zhuo Zhang; Bing-Hua Jiang; Jia Luo; Xianglin Shi
Sulforaphane inhibited expression of hypoxia-inducible factor-1alpha in human tongue squamous cancer cells and prostate cancer cells.
International journal of cancer. Journal international du cancer 2008;123(6):1255-61.
2008: Bing-Hua Jiang; Ling-Zhi Liu
Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2008;11(3):63-76.
2008: Shuhong Guo; Olga Bragina; Yuexian Xu; Zongxian Cao; Hu Chen; Bo Zhou; Marilee Morgan; Yong Lin; Bing-Hua Jiang; Ke Jian Liu; Honglian Shi
Glucose up-regulates HIF-1 alpha expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status.
Journal of neurochemistry 2008;105(5):1849-60.
2008: Pai-Hao Yang; William K C Cheung; Ying Peng; Ming-Liang He; Guo-Qing Wu; Dan Xie; Bing-Hua Jiang; Qiu-Hua Huang; Zhu Chen; Marie C M Lin; Hsiang-Fu Kung
Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal.
The Journal of biological chemistry 2008;283(13):8486-95.
2008: Liying Wang; Neelam Azad; Lalana Kongkaneramit; Fei Chen; Yongju Lu; Bing-Hua Jiang; Yon Rojanasakul
The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3072-80.
2008: Bing-Hua Jiang; Ling-Zhi Liu
AKT signaling in regulating angiogenesis.
Current cancer drug targets 2008;8(1):19-26.
2008: Haitao Luo; Bing-Hua Jiang; Sarah M King; Yi Charlie Chen
Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids.
Nutrition and cancer 2008;60(6):800-9.
2008: Hua Yao; Lan Guo; Bing-Hua Jiang; Jia Luo; Xianglin Shi
Oxidative stress and chromium(VI) carcinogenesis.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2008;27(2):77-88.
2008: Bing-Hua Jiang; Ling-Zhi Liu
PI3K/PTEN signaling in tumorigenesis and angiogenesis.
Biochimica et biophysica acta 2008;1784(1):150-8.
2007: Jing Fang; Min Ding; Lily Yang; Ling-Zhi Liu; Bing-Hua Jiang
PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.
Cellular signalling 2007;19(12):2487-97.
2007: Chang Xia; Qiao Meng; Ling-Zhi Liu; Yongyut Rojanasakul; Xin-Ru Wang; Bing-Hua Jiang
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor.
Cancer research 2007;67(22):10823-30.
2007: Ling-Zhi Liu; Xiang-Dong Zhou; Guisheng Qian; Xianglin Shi; Jing Fang; Bing-Hua Jiang
AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway.
Cancer research 2007;67(13):6325-32.
2007: Weiming Ouyang; Jingxia Li; Dongyun Zhang; Bing-Hua Jiang; Dr Chuanshu Huang
PI-3K/Akt signal pathway plays a crucial role in arsenite-induced cell proliferation of human keratinocytes through induction of cyclin D1.
Journal of cellular biochemistry 2007;101(4):969-78.
2007: Valerie G Walker; Amanda Ammer; Zongxian Cao; Anne C Clump; Bing-Hua Jiang; Laura C Kelley; Scott A Weed; Henry Zot; Daniel C Flynn
PI3K activation is required for PMA-directed activation of cSrc by AFAP-110.
American journal of physiology. Cell physiology 2007;293(1):C119-32.
2007: Zongxian Cao; Ling-Zhi Liu; Dan A. Dixon; Jenny Z Zheng; bala chandran; Bing-Hua Jiang
Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells.
Cellular signalling 2007;19(7):1542-53.
2007: Xiao-Song Zhong; Ling-Zhi Liu; Heath Devin Skinner; Zongxian Cao; Min Ding; Bing-Hua Jiang
Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells.
Biochemical and biophysical research communications 2007;358(1):92-8.
2007: Dan Meng; Xianglin Shi; Bing-Hua Jiang; Jing Fang
Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species.
Free radical biology & medicine 2007;42(11):1651-60.
2007: Zhao-Dong Li; Ling-Zhi Liu; Xianglin Shi; Jing Fang; Bing-Hua Jiang
Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation.
Biochemical and biophysical research communications 2007;357(2):517-23.
2007: Jing Fang; Qiong Zhou; Ling-Zhi Liu; Chang Xia; Xiaowen Hu; Xianglin Shi; Bing-Hua Jiang
Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression.
Carcinogenesis 2007;28(4):858-64.
2007: Jing Fang; Qiong Zhou; Xiang-lin Shi; Bing-Hua Jiang
Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells.
Carcinogenesis 2007;28(3):713-23.
2007: Beibei Fu; Jing Xue; Zhaodong Li; Xianglin Shi; Bing-Hua Jiang; Jing Fang
Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.
Molecular cancer therapeutics 2007;6(1):220-6.
2007: Qiong Zhou; Ling-Zhi Liu; Beibei Fu; Xiaowen Hu; Xianglin Shi; Jing Fang; Bing-Hua Jiang
Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells.
Carcinogenesis 2007;28(1):28-37.
2006: Qiao Meng; Chang Xia; Jing Fang; Yon Rojanasakul; Bing-Hua Jiang
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway.
Cellular signalling 2006;18(12):2262-71.
2006: Ling-Zhi Liu; Xiao-Wen Hu; Chang Xia; Jie He; Qiong Zhou; Xianglin Shi; Jing Fang; Bing-Hua Jiang
Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1alpha expression through activation of AKT and P70S6K1 in human ovarian cancer cells.
Free radical biology & medicine 2006;41(10):1521-33.
2006: Jing Fang; Qiao Meng; Peter K Vogt; Ruiwen Zhang; Bing-Hua Jiang
A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability.
Journal of cellular physiology 2006;209(2):261-5.
2006: Qiong Zhou; Dan Meng; Bing Yan; Bing-Hua Jiang; Jing Fang
Transactivation of epidermal growth factor receptor by insulin-like growth factor 1 requires basal hydrogen peroxide.
FEBS letters 2006;580(22):5161-6.
2006: Chang Xia; Qiao Meng; Zongxian Cao; Xianglin Shi; Bing-Hua Jiang
Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression.
Journal of cellular physiology 2006;209(1):56-66.
2006: Xiang-Hong Peng; Prasanthi Karna; Zehong Cao; Bing-Hua Jiang; Muxiang Zhou; Lily Yang
Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression.
The Journal of biological chemistry 2006;281(36):25903-14.
2006: Min Ding; Rentian Feng; Shiow Y Wang; Linda Bowman; Yongju Lu; Yong Qian; Vincent Castranova; Bing-Hua Jiang; Xianglin Shi
Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity.
The Journal of biological chemistry 2006;281(25):17359-68.
2006: Pithi Chanvorachote; Ubonthip Nimmannit; Christian Stehlik; Liying Wang; Bing-Hua Jiang; Boonsri Ongpipatanakul; Yon Rojanasakul
Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination.
Cancer research 2006;66(12):6353-60.
2006: Bing-Hua Jiang; Ling-Zhi Liu; Rosana Schafer; Daniel C Flynn; John Barnett
A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxia-inducible factor 1alpha expression.
BMC cancer 2006;6():204.
2006: Nicole Victor; Andre Ivy; Bing-Hua Jiang; Faton H Agani
Involvement of HIF-1 in invasion of Mum2B uveal melanoma cells.
Clinical & experimental metastasis 2006;23(1):87-96.
2005: Ling-Zhi Liu; Jing Fang; Qiong Zhou; Xiaowen Hu; Xianglin Shi; Bing-Hua Jiang
Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer.
Molecular pharmacology 2005;68(3):635-43.
2005: Anna-Liisa Nieminen; Suparna Qanungo; Elizabeth A Schneider; Bing-Hua Jiang; Faton H Agani
Mdm2 and HIF-1alpha interaction in tumor cells during hypoxia.
Journal of cellular physiology 2005;204(2):364-9.
2005: Yong Qian; Xiaosong Zhong; Daniel C Flynn; Jenny Z Zheng; Meng Qiao; Chuanyue Wu; Shoukat Dedhar; Xianglin Shi; Bing-Hua Jiang
ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling.
Oncogene 2005;24(19):3154-65.
2005: Djordje Medan; Liying Wang; David Toledo; Bin Lu; Christian Stehlik; Bing-Hua Jiang; Xianglin Shi; Yon Rojanasakul
Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages.
Journal of cellular physiology 2005;203(1):78-84.
2005: Jing Fang; Chang Xia; Zongxian Cao; Jenny Z Zheng; Eddie Reed; Bing-Hua Jiang
Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):342-53.
2004: Xiao-Song Zhong; Jenny Z Zheng; Eddie Reed; Bing-Hua Jiang
SU5416 inhibited VEGF and HIF-1alpha expression through the PI3K/AKT/p70S6K1 signaling pathway.
Biochemical and biophysical research communications 2004;324(2):471-80.
2004: Heath Devin Skinner; Jenny Z Zheng; Jing Fang; Faton H Agani; Bing-Hua Jiang
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
The Journal of biological chemistry 2004;279(44):45643-51.
2004: Zongxian Cao; Jing Fang; Chang Xia; Xianglin Shi; Bing-Hua Jiang
trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5253-63.
2004: Ning Gao; Daniel C Flynn; Zhuo Zhang; Xiao-Song Zhong; Valerie Walker; Ke Jian Liu; Xianglin Shi; Bing-Hua Jiang
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
American journal of physiology. Cell physiology 2004;287(2):C281-91.
2004: Ying Peng; Bing-Hua Jiang; Pai-Hao Yang; Zongxian Cao; Xianglin Shi; Marie C M Lin; Ming-Liang He; Hsiang-Fu Kung
Phosphatidylinositol 3-kinase signaling is involved in neurogenesis during Xenopus embryonic development.
The Journal of biological chemistry 2004;279(27):28509-14.
2004: Jing Fang; Zongxian Cao; Yi Charlie Chen; Eddie Reed; Bing-Hua Jiang
9-beta-D-arabinofuranosyl-2-fluoroadenine inhibits expression of vascular endothelial growth factor through hypoxia-inducible factor-1 in human ovarian cancer cells.
Molecular pharmacology 2004;66(1):178-86.
2004: Rentian Feng; Linda L Bowman; Yongju Lu; Stephen S Leonard; Xianglin Shi; Bing-Hua Jiang; Vincent Castranova; Val Vallyathan; Min Ding
Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway.
Nutrition and cancer 2004;50(1):80-9.
2004: Zhuo Zhang; Ning Gao; Hengjun He; Chuanshu Huang; Bing-Hua Jiang; Luo Jia; Xianglin Shi
The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry.
Molecular and cellular biochemistry 2004;255(1-2):239-45.
2004: Suwei Wang; Fei Chen; Zhuo Zhang; Bing-Hua Jiang; Luo Jia; Xianglin Shi
NF-kappaB prevents cells from undergoing Cr(VI)-induced apoptosis.
Molecular and cellular biochemistry 2004;255(1-2):129-37.
2004: Ning Gao; Liqin Shen; Zhuo Zhang; Stephen S Leonard; Hengjun He; Xue-Guang Zhang; Xianglin Shi; Bing-Hua Jiang
Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells.
Molecular and cellular biochemistry 2004;255(1-2):33-45.
2004: Heath Devin Skinner; Xiao-Song Zhong; Ning Gao; Xianglin Shi; Bing-Hua Jiang
Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells.
Molecular and cellular biochemistry 2004;255(1-2):19-23.
2004: Jingxia Li; Gerard Davidson; Yi Huang; Bing-Hua Jiang; Xianglin Shi; Max Costa; Chuanshu Huang
Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells.
Cancer research 2004;64(1):94-101.
2004: Yong Qian; Linda Corum; Qiao Meng; John Blenis; Jenny Z Zheng; Xianglin Shi; Daniel C Flynn; Bing-Hua Jiang
PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration.
American journal of physiology. Cell physiology 2004;286(1):C153-63.
2003: Ning Gao; Zhuo Zhang; Bing-Hua Jiang; Xianglin Shi
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer.
Biochemical and biophysical research communications 2003;310(4):1124-32.
2003: Stephen S Leonard; Chang Xia; Bing-Hua Jiang; Beth Stinefelt; Hillar Klandorf; Gabriel K Harris; Xianglin Shi
Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses.
Biochemical and biophysical research communications 2003;309(4):1017-26.
2003: Justin M Summy; Yong Qian; Bing-Hua Jiang; Anne Guappone-Koay; Amanda Gatesman; Xianglin Shi; Daniel C Flynn
The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src.
Journal of cell science 2003;116(Pt 12):2585-98.
2002: Ning Gao; Bing-Hua Jiang; Stephen S Leonard; Linda Corum; Zhuo Zhang; Jenny R Roberts; Jim Antonini; Jenny Z Zheng; Daniel C Flynn; Vincent Castranova; Xianglin Shi
p38 Signaling-mediated hypoxia-inducible factor 1alpha and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells.
The Journal of biological chemistry 2002;277(47):45041-8.
2002: Chuanshu Huang; Jingxia Li; Qingdong Ke; Stephen S Leonard; Bing-Hua Jiang; Xiao-Song Zhong; Max Costa; Vincent Castranova; Xianglin Shi
Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
Cancer research 2002;62(20):5689-97.
2002: Ning Gao; Min Ding; Jenny Z Zheng; Zhuo Zhang; Stephen S Leonard; Ke Jian Liu; Xianglin Shi; Bing-Hua Jiang
Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species.
The Journal of biological chemistry 2002;277(35):31963-71.
2002: David Shi; Bing-Hua Jiang
Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2002;21(3):233-42.
2001: Joseph M Baisden; Amanda Gatesman; Lidia Cherezova; Bing-Hua Jiang; Daniel C Flynn
The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.
Oncogene 2001;20(45):6607-16.
2001: Bing-Hua Jiang; G Jiang; Jenny Z Zheng; Z Lu; Tony Hunter; Peter K Vogt
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(7):363-9.
2001: Y Qian; Bing-Hua Jiang; Daniel C Flynn; Stephen S Leonard; S Wang; Z Zhang; J Ye; F Chen; L Wang; X Shi
Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions.
Molecular and cellular biochemistry 2001;222(1-2):199-204.
2000: Y Li; Bing-Hua Jiang; W Y Ensign; Peter K Vogt; Jiahuai Han
Myogenic differentiation requires signalling through both phosphatidylinositol 3-kinase and p38 MAP kinase.
Cellular signalling 2000;12(11-12):751-7.
2000: Bing-Hua Jiang; Jenny Z Zheng; Masahiro Aoki; Peter K Vogt
Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1749-53.
1999: Peter K Vogt; Masahiro Aoki; I Bottoli; Hwai Wen Chang; S Fu; Andreas Hecht; Jason S Iacovoni; Bing-Hua Jiang; Ulrich Kruse
A random walk in oncogene space: the quest for targets.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(12):777-84.
1999: Tibor Pechan; Bing-Hua Jiang; D Steckler; L Ye; L Lin; Dawn S Luthe; W Paul Williams
Characterization of three distinct cDNA clones encoding cysteine proteinases from maize (Zea mays L.) callus.
Plant molecular biology 1999;40(1):111-9.
1999: Bing-Hua Jiang; Masahiro Aoki; Jenny Z Zheng; Jiali Li; Peter K Vogt
Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2077-81.
1998: Bing-Hua Jiang; Jenny Z Zheng; Peter K Vogt
An essential role of phosphatidylinositol 3-kinase in myogenic differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14179-83.
1998: Gregg L Semenza; Faton H Agani; Narayan Iyer; Bing-Hua Jiang; S Leung; Charles M Wiener; A Yu
Hypoxia-inducible factor 1: from molecular biology to cardiopulmonary physiology.
Chest 1998;114(1 Suppl):40S-45S.
1998: C Martin; AY Yu; Bing-Hua Jiang; Lowell E Davis; D Kimberly; Alan Roger (Roger) Hohimer; Gregg L Semenza
Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1.
American journal of obstetrics and gynecology 1998;178(3):527-34.
1997: Bing-Hua Jiang; Faton H Agani; Antonino Passaniti; Gregg L Semenza
V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.
Cancer research 1997;57(23):5328-35.
1997: Bing-Hua Jiang; Jenny Z Zheng; Steve W Leung; R Roe; Gregg L Semenza
Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension.
The Journal of biological chemistry 1997;272(31):19253-60.
1997: Patty J Lee; Bing-Hua Jiang; Beek Yoke Chin; Narayan Iyer; Jawed Alam; Gregg L Semenza; Augustine M K Choi
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia.
The Journal of biological chemistry 1997;272(9):5375-81.
1997: Gregg L Semenza; Faton H Agani; GM Booth; J Forsythe; Narayan Iyer; Bing-Hua Jiang; S Leung; R Roe; Charles M Wiener; A Yu
Structural and functional analysis of hypoxia-inducible factor 1.
Kidney international 1997;51(2):553-5.
1996: Gregg L Semenza; Bing-Hua Jiang; Steve W Leung; R Passantino; J P Concordet; Pascal Maire; Agata Giallongo
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1.
The Journal of biological chemistry 1996;271(51):32529-37.
1996: Bing-Hua Jiang; Gregg L Semenza; C Bauer; Hugo H Marti
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension.
The American journal of physiology 1996;271(4 Pt 1):C1172-80.
1996: J A Forsythe; Bing-Hua Jiang; Narayan Iyer; Faton H Agani; Steve W Leung; Robert D Koos; Gregg L Semenza
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.
Molecular and cellular biology 1996;16(9):4604-13.
1996: Bing-Hua Jiang; E Rue; G L Wang; R Roe; Gregg L Semenza
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1.
The Journal of biological chemistry 1996;271(30):17771-8.
1995: G L Wang; Bing-Hua Jiang; Gregg L Semenza
Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.
Biochemical and biophysical research communications 1995;216(2):669-75.
1995: Bing-Hua Jiang; U Siregar; K O Willeford; D S Luthe; W P Williams
Association of a 33-kilodalton cysteine proteinase found in corn callus with the inhibition of fall armyworm larval growth.
Plant physiology 1995;108(4):1631-40.
1995: G L Wang; Bing-Hua Jiang; Gregg L Semenza
Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.
Biochemical and biophysical research communications 1995;212(2):550-6.
1995: G L Wang; Bing-Hua Jiang; E A Rue; Gregg L Semenza
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5510-4.