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Weiwu Jiang

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Chemicals & Drugs

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Reverse Transcriptase Polymerase Chain Reaction

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Publications

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Binoy Shivanna; Lihua Wang; Stephen E Welty; Wenyan Zhang; Xanthi I Couroucli; Weiwu Jiang; Bhagavatula Moorthy
Functional deficiency of aryl hydrocarbon receptor augments oxygen toxicity-induced alveolar simplification in newborn mice.
Binoy Shivanna; Lihua Wang; Stephen E Welty; Chun Chu; Xanthi I Couroucli; Weiwu Jiang; Bhagavatula Moorthy
Omeprazole attenuates hyperoxic injury in H441 cells via the aryl hydrocarbon receptor.
Xanthi I Couroucli; Weiwu Jiang; Yan-hong Wei Liang; Lihua Wang; Peiying Yang; Roberto Barrios; Bhagavatula Moorthy
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.

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All Publications

2013: Binoy Shivanna; Lihua Wang; Stephen E Welty; Wenyan Zhang; Xanthi I Couroucli; Weiwu Jiang; Bhagavatula Moorthy
Functional deficiency of aryl hydrocarbon receptor augments oxygen toxicity-induced alveolar simplification in newborn mice.
Toxicology and applied pharmacology 2013;267(3):209-17.
2011: Binoy Shivanna; Lihua Wang; Stephen E Welty; Chun Chu; Xanthi I Couroucli; Weiwu Jiang; Bhagavatula Moorthy
Omeprazole attenuates hyperoxic injury in H441 cells via the aryl hydrocarbon receptor.
Free radical biology & medicine 2011;51(10):1910-7.
2011: Xanthi I Couroucli; Weiwu Jiang; Yan-hong Wei Liang; Lihua Wang; Peiying Yang; Roberto Barrios; Bhagavatula Moorthy
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.
Toxicology and applied pharmacology 2011;256(2):83-94.
2011: Binoy Shivanna; Lihua Wang; Xanthi I Couroucli; Weiwu Jiang; Bhagavatula Moorthy
Omeprazole attenuates hyperoxic lung injury in mice via aryl hydrocarbon receptor activation and is associated with increased expression of cytochrome P4501A enzymes.
The Journal of pharmacology and experimental therapeutics 2011;339(1):106-14.
2011: Weiwu Jiang; Xanthi I Couroucli; Lihua Wang; Roberto Barrios; Bhagavatula Moorthy
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo.
Biochemical and biophysical research communications 2011;407(1):79-85.
2010: Weiwu Jiang; Lihua Wang; Sudha R Kondraganti; Inayat S Fazili; Xanthi I Couroucli; Edward A Felix; Bhagavatula Moorthy
Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo.
The Journal of pharmacology and experimental therapeutics 2010;335(2):369-79.
2010: Inayat S Fazili; Weiwu Jiang; Lihua Wang; Edward A Felix; Tanvir Khatlani; Xavier COUMOUL; Robert Barouki; Bhagavatula Moorthy
Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional activation of the CYP1A1 promoter.
The Journal of pharmacology and experimental therapeutics 2010;333(1):99-109.
2009: Weiwu Jiang; Lihua Wang; Weisheng Zhang; Richard Coffee; Inayat S Fazili; Bhagavatula Moorthy
Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters.
Biochemical and biophysical research communications 2009;390(4):1419-24.
2008: Kushal Y Bhakta; Weiwu Jiang; Xanthi I Couroucli; Inayat S Fazili; Kathirvel Muthiah; Bhagavatula Moorthy
Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury.
Toxicology and applied pharmacology 2008;233(2):169-78.
2008: Sudha R Kondraganti; Weiwu Jiang; Anil K Jaiswal; Bhagavatula Moorthy
Persistent induction of hepatic and pulmonary phase II enzymes by 3-methylcholanthrene in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2008;102(2):337-44.
2007: Bhagavatula Moorthy; Kathirvel Muthiah; Inayat S Fazili; Sudha R Kondraganti; Lihua Wang; Xanthi I Couroucli; Weiwu Jiang
3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells.
Biochemical and biophysical research communications 2007;354(4):1071-7.
2006: Xanthi I Couroucli; Yanhong W Liang; Weiwu Jiang; Roberto Barrios; Bhagavatula Moorthy
Attenuation of oxygen-induced abnormal lung maturation in rats by retinoic acid: possible role of cytochrome P4501A enzymes.
The Journal of pharmacology and experimental therapeutics 2006;317(3):946-54.
2006: Xanthi I Couroucli; Yan-Hong Wei; Weiwu Jiang; Kathirvel Muthiah; Lee W Evey; Roberto Barrios; Bhagavatula Moorthy
Modulation of pulmonary cytochrome P4501A1 expression by hyperoxia and inhaled nitric oxide in the newborn rat: implications for lung injury.
Pediatric research 2006;59(3):401-6.
2005: Sudha R Kondraganti; Kathirvel Muthiah; Weiwu Jiang; Roberto Barrios; Bhagavatula Moorthy
Effects of 3-methylcholanthrene on gene expression profiling in the rat using cDNA microarray analyses.
Chemical research in toxicology 2005;18(11):1634-41.
2005: Anuj Sinha; Kathirvel Muthiah; Weiwu Jiang; Xanthi I Couroucli; Roberto Barrios; Bhagavatula Moorthy
Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone.
Toxicological sciences : an official journal of the Society of Toxicology 2005;87(1):204-12.
2004: Weiwu Jiang; Stephen E Welty; Xanthi I Couroucli; Roberto Barrios; Sudha R Kondraganti; Kathirvel Muthiah; Ling Yu; Stephen E Avery; Bhagavatula Moorthy
Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
The Journal of pharmacology and experimental therapeutics 2004;310(2):512-9.
2003: Bhagavatula Moorthy; Kimberly P Miller; Weiwu Jiang; E Spencer Williams; Sudha R Kondraganti; Kenneth S Ramos
Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate genotoxic intermediates.
The Journal of pharmacology and experimental therapeutics 2003;305(1):394-401.
2003: Sudha R Kondraganti; Pedro Fernandez-Salguero; Frank J Gonzalez; Kenneth S Ramos; Weiwu Jiang; Bhagavatula Moorthy
Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
International journal of cancer. Journal international du cancer 2003;103(1):5-11.
2002: Sudha R Kondraganti; Weiwu Jiang; Bhagavatula Moorthy
Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.
The Journal of pharmacology and experimental therapeutics 2002;303(3):945-51.
2002: Bhagavatula Moorthy; Kimberly P Miller; Weiwu Jiang; Kenneth S Ramos
The atherogen 3-methylcholanthrene induces multiple DNA adducts in mouse aortic smooth muscle cells: role of cytochrome P4501B1.
Cardiovascular research 2002;53(4):1002-9.