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Ying Jiang

Research Profile

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Enzyme-Linked Immunosorbent Assay

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Dun-Sheng Yang; Urmi Bandyopadhyay; Ana Maria Cuervo; Ying Jiang; Susmita Kaushik; Asok Kumar; Efrat Levy; Paul M Mathews; Panaiyur S Mohan; Masuo Ohno; Monika Pawlik; Corrinne M Peterhoff; Stephen D Schmidt; Peter St George-Hyslop; Philip Stavrides; Daniel W Wesson; David Westaway; Donald A Wilson; Austin Yang; Ralph A. Nixon
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
Dun-Sheng Yang; Philip Stavrides; Panaiyur S Mohan; Susmita Kaushik; Asok Kumar; Masuo Ohno; Stephen D Schmidt; Daniel Wesson; Urmi Bandyopadhyay; Ying Jiang; Monika Pawlik; Corrinne M Peterhoff; Austin Yang; Donald A Wilson; Peter St George-Hyslop; David Westaway; Paul M Mathews; Efrat Levy; Ana Maria Cuervo; Ralph A Nixon
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
Stephen D. Ginsberg; Melissa J Alldred; Scott E Counts; Anne M Cataldo; Rachael L Neve; Ying Jiang; Joanne Wuu; Moses V Chao; Elliott J Mufson; Ralph A. Nixon; Shaoli Che
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.

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All Publications

2011: Dun-Sheng Yang; Urmi Bandyopadhyay; Ana Maria Cuervo; Ying Jiang; Susmita Kaushik; Asok Kumar; Efrat Levy; Paul M Mathews; Panaiyur S Mohan; Masuo Ohno; Monika Pawlik; Corrinne M Peterhoff; Stephen D Schmidt; Peter St George-Hyslop; Philip Stavrides; Daniel W Wesson; David Westaway; Donald A Wilson; Austin Yang; Ralph A. Nixon
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
Autophagy 2011;7(7):788-9.
2011: Dun-Sheng Yang; Philip Stavrides; Panaiyur S Mohan; Susmita Kaushik; Asok Kumar; Masuo Ohno; Stephen D Schmidt; Daniel Wesson; Urmi Bandyopadhyay; Ying Jiang; Monika Pawlik; Corrinne M Peterhoff; Austin Yang; Donald A Wilson; Peter St George-Hyslop; David Westaway; Paul M Mathews; Efrat Levy; Ana Maria Cuervo; Ralph A Nixon
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
Brain : a journal of neurology 2011;134(Pt 1):258-77.
2010: Stephen D. Ginsberg; Melissa J Alldred; Scott E Counts; Anne M Cataldo; Rachael L Neve; Ying Jiang; Joanne Wuu; Moses V Chao; Elliott J Mufson; Ralph A. Nixon; Shaoli Che
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.
Biological psychiatry 2010;68(10):885-93.
2010: Ying Jiang; Kerry A Mullaney; Corrinne M Peterhoff; Shaoli Che; Stephen D Schmidt; Anne Boyer-Boiteau; Stephen D. Ginsberg; Anne M Cataldo; Paul Mathews; Ralph A. Nixon
Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1630-5.
2008: Mala V Rao; Panaiyur S Mohan; Corrinne M Peterhoff; Dun-Sheng Yang; Stephen D Schmidt; Philip H Stavrides; Jabbar Campbell; Yuanxin Chen; Ying Jiang; Peter A Paskevich; Anne M Cataldo; Vahram Haroutunian; Ralph A. Nixon
Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(47):12241-54.
2008: Anne M Cataldo; Paul Mathews; Anne Boyer Boiteau; Linda C Hassinger; Corrinne M Peterhoff; Ying Jiang; Kerry Mullaney; Rachael L Neve; Jean Gruenberg; Ralph A. Nixon
Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.
The American journal of pathology 2008;173(2):370-84.
2005: W Haung Yu; Ana Maria Cuervo; Asok Kumar; Corrinne M Peterhoff; Stephen D Schmidt; Ju-Hyun Lee; Panaiyur S Mohan; Marc Mercken; Mark Farmery; Lars O Tjernberg; Ying Jiang; karen duff; Yasuo Uchiyama; Jan Näslund; Paul Mathews; Anne M Cataldo; Ralph A. Nixon
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.
The Journal of cell biology 2005;171(1):87-98.
2005: Stephen D Schmidt; Ying Jiang; Ralph A. Nixon; Paul Mathews
Tissue processing prior to protein analysis and amyloid-beta quantitation.
Methods in molecular biology (Clifton, N.J.) 2005;299():267-78.
2003: Olivera M Grbovic; Paul Mathews; Ying Jiang; Stephen D Schmidt; Ravi Dinakar; Nicole B Summers-Terio; Brian P Ceresa; Ralph A. Nixon; Anne M Cataldo
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production.
The Journal of biological chemistry 2003;278(33):31261-8.
2002: Paul Mathews; Ying Jiang; Stephen D Schmidt; Olivera M Grbovic; Marc Mercken; Ralph A. Nixon
Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments.
The Journal of biological chemistry 2002;277(39):36415-24.
2002: Paul Mathews; Carolyn B Guerra; Ying Jiang; Olivera M Grbovic; Benjamin H Kao; Stephen D Schmidt; Ravi Dinakar; Marc Mercken; Annette Hille-Rehfeld; Jack Rohrer; Pankaj Mehta; Anne M Cataldo; Ralph A. Nixon
Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.
The Journal of biological chemistry 2002;277(7):5299-307.
2000: Paul Mathews; Anne M Cataldo; B H Kao; A G Rudnicki; X Qin; J L Yang; Ying Jiang; M Picciano; Christine M Hulette; Carol F Lippa; Thomas D Bird; David Nochlin; J Walter; Christian Haass; L Lévesque; Paul E Fraser; Athena Andreadis; Ralph A. Nixon
Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.
Molecular medicine (Cambridge, Mass.) 2000;6(10):878-91.