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Susumu Adachi

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Michio Kuwahara; Yoshihiro Mori; Yumi Noda; Tatemitsu Rai; Susumu Adachi; Wataru Akita; Tomoki Asai; Junichi Ishigami; Satomi Shikuma; Yusuke Tsukamoto; Shinichi Uchida; Sei Sasaki
Type II diabetes mellitus is a risk factor for heart failure in pre-dialysis patients.
Yasuhiro Maejima; Kiyoshi Nobori; Yuichi Ono; Susumu Adachi; Jun-Ichi Suzuki; Kenzo Hirao; Mitsuaki Isobe; Hiroshi Ito
Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.
Masatoshi Komura; Jun-Ichi Suzuki; Susumu Adachi; Atsushi Takahashi; Kenichiro Otomo; Junichi Nitta; Mitsuhiro Nishizaki; Tohru Obayashi; Akihiko Nogami; Yasuhiro Satoh; Kaoru Okishige; Hitoshi Hachiya; Kenzo Hirao; Mitsuaki Isobe
Clinical course of arrhythmogenic right ventricular cardiomyopathy in the era of implantable cardioverter-defibrillators and radiofrequency catheter ablation.

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All Publications

2012: Michio Kuwahara; Yoshihiro Mori; Yumi Noda; Tatemitsu Rai; Susumu Adachi; Wataru Akita; Tomoki Asai; Junichi Ishigami; Satomi Shikuma; Yusuke Tsukamoto; Shinichi Uchida; Sei Sasaki
Type II diabetes mellitus is a risk factor for heart failure in pre-dialysis patients.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2012;16(6):541-7.
2011: Yasuhiro Maejima; Kiyoshi Nobori; Yuichi Ono; Susumu Adachi; Jun-Ichi Suzuki; Kenzo Hirao; Mitsuaki Isobe; Hiroshi Ito
Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(3):589-95.
2010: Masatoshi Komura; Jun-Ichi Suzuki; Susumu Adachi; Atsushi Takahashi; Kenichiro Otomo; Junichi Nitta; Mitsuhiro Nishizaki; Tohru Obayashi; Akihiko Nogami; Yasuhiro Satoh; Kaoru Okishige; Hitoshi Hachiya; Kenzo Hirao; Mitsuaki Isobe
Clinical course of arrhythmogenic right ventricular cardiomyopathy in the era of implantable cardioverter-defibrillators and radiofrequency catheter ablation.
International heart journal 2010;51(1):34-40.
2008: Yasuhiro Maejima; Susumu Adachi; Hiroshi Ito; Kenzo Hirao; Mitsuaki Isobe
Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage.
Aging cell 2008;7(2):125-36.
2007: Susumu Adachi
[Cardiomyocyte hypertrophy].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 4():287-91.
2006: Kino Morikawa-Futamatsu; Susumu Adachi; Yasuhiro Maejima; Mimi Tamamori-Adachi; Jun-ichi Suzuki; Shigetaka Kitajima; Hiroshi Ito; Mitsuaki Isobe
HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
Life sciences 2006;79(14):1380-90.
2006: Hideki Futamatsu; Jun-ichi Suzuki; Susumu Adachi; Hiroyuki Okada; Kiyoshi Otomo; Takahiro Ohara; Yuji Hashimoto; Tsunekazu Kakuta; Yoshito Iesaka; Hiroaki Yamaguchi; Harumizu Sakurada; Akira Sato; Tohru Obayashi; Akihiro Niwa; Kenzo Hirao; Mitsuaki Isobe
Utility of gallium-67 scintigraphy for evaluation of cardiac sarcoidosis with ventricular tachycardia.
The international journal of cardiovascular imaging 2006;22(3-4):443-8.
2006: Hideki Futamatsu; Jun-ichi Suzuki; Noritaka Koga; Susumu Adachi; Hisanori Kosuge; Yasuhiro Maejima; Takaaki Haga; Kenzo Hirao; Richard Horuk; Mitsuaki Isobe
A CCR1 antagonist prevents the development of experimental autoimmune myocarditis in association with T cell inactivation.
Journal of molecular and cellular cardiology 2006;40(6):853-61.
2005: Kiyoshi Tamura; Bayin Hua; Susumu Adachi; Isil Guney; Junya Kawauchi; Masaki Morioka; Mimi Tamamori-Adachi; Yujiro Tanaka; Yusaku Nakabeppu; Makoto Sunamori; John M Sedivy; Shigetaka Kitajima
Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation.
The EMBO journal 2005;24(14):2590-601.
2005: Takeshi Takahashi; Fumiyuki Yamasaki; Tamotsu Sudo; Hiroaki Itamochi; Susumu Adachi; Mimi Tamamori-Adachi; Naoto T Ueno
Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.
Molecular cancer therapeutics 2005;4(7):1039-46.
2005: Hideki Futamatsu; Jun-ichi Suzuki; Shinya Mizuno; Noritaka Koga; Susumu Adachi; Hisanori Kosuge; Yasuhiro Maejima; Kenzo Hirao; Toshikazu Nakamura; Mitsuaki Isobe
Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines.
Circulation research 2005;96(8):823-30.
2005: Yasuhiro Maejima; Susumu Adachi; Kino Morikawa; Hiroshi Ito; Mitsuaki Isobe
Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation.
Journal of molecular and cellular cardiology 2005;38(1):163-74.
2003: Yasuhiro Maejima; Susumu Adachi; Hiroshi Ito; Kiyoshi Nobori; Mimi Tamamori-Adachi; Mitsuaki Isobe
Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclin A-associated kinase activity.
Cardiovascular research 2003;59(2):308-20.
2003: Mimi Tamamori-Adachi; Hiroshi Ito; Piyamas Sumrejkanchanakij; Susumu Adachi; Michiaki Hiroe; Masato Shimizu; Junya Kawauchi; Makoto Sunamori; Fumiaki Marumo; Shigetaka Kitajima; Masa-Aki Ikeda
Critical role of cyclin D1 nuclear import in cardiomyocyte proliferation.
Circulation research 2003;92(1):e12-9.
2002: Kiyoshi Nobori; Hiroshi Ito; Mimi Tamamori-Adachi; Susumu Adachi; Yuichi Ono; Junya Kawauchi; Shigetaka Kitajima; Fumiaki Marumo; Mitsuaki Isobe
ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3.
Journal of molecular and cellular cardiology 2002;34(10):1387-97.
2002: Mimi Tamamori-Adachi; Hiroshi Ito; Kiyoshi Nobori; Kentaro Hayashida; Junya Kawauchi; Susumu Adachi; Masa-Aki Ikeda; Shigetaka Kitajima
Expression of cyclin D1 and CDK4 causes hypertrophic growth of cardiomyocytes in culture: a possible implication for cardiac hypertrophy.
Biochemical and biophysical research communications 2002;296(2):274-80.
2001: T Nozato; Hiroshi Ito; M Watanabe; Yuichi Ono; Susumu Adachi; H Tanaka; Michiaki Hiroe; M Sunamori; F Marum
Overexpression of cdk Inhibitor p16INK4a by adenovirus vector inhibits cardiac hypertrophy in vitro and in vivo: a novel strategy for the gene therapy of cardiac hypertrophy.
Journal of molecular and cellular cardiology 2001;33(8):1493-504.
2001: Susumu Adachi; Hiroshi Ito; Mimi Tamamori-Adachi; Yuichi Ono; T Nozato; Shinya Abe; Fumiaki Marumo; Michiaki Hiroe
Cyclin A/cdk2 activation is involved in hypoxia-induced apoptosis in cardiomyocytes.
Circulation research 2001;88(4):408-14.
2000: Yuichi Ono; Hiroshi Ito; M Tamamori; T Nozato; Susumu Adachi; Shinya Abe; Fumiaki Marumo; Michiaki Hiroe
Role and relation of p70 S6 and extracellular signal-regulated kinases in the phenotypic changes of hypertrophy of cardiac myocytes.
Japanese circulation journal 2000;64(9):695-700.
2000: T Nozato; Hiroshi Ito; M Tamamori; Susumu Adachi; Shinya Abe; Fumiaki Marumo; Michiaki Hiroe
G1 cyclins are involved in the mechanism of cardiac myocyte hypertrophy induced by angiotensin II.
Japanese circulation journal 2000;64(8):595-601.
1999: Hiroshi Ito; T Shimojo; H Fujisaki; M Tamamori; Shigeru Ishiyama; Susumu Adachi; Shinya Abe; Fumiaki Marumo; Michiaki Hiroe
Thermal preconditioning protects rat cardiac muscle cells from doxorubicin-induced apoptosis.
Life sciences 1999;64(9):755-61.
1998: Susumu Adachi; Hiroshi Ito; M Tamamori; M Tanaka; Fumiaki Marumo; Michiaki Hiroe
Skeletal and smooth muscle alpha-actin mRNA in endomyocardial biopsy samples of dilated cardiomyopathy patients.
Life sciences 1998;63(20):1779-91.
1997: Hiroshi Ito; D Bell; M Tamamori; T Nozato; T Shimojo; Susumu Adachi; Shinya Abe; Fumiaki Marumo; Michiaki Hiroe
Calcitonin gene-related peptide (CGRP) and hypertrophy of cardiomyocytes.
Heart and vessels 1997;Suppl 12():15-7.
1996: Hiroshi Ito; Susumu Adachi; M Tamamori; H Fujisaki; M Tanaka; M Lin; H Akimoto; Fumiaki Marumo; Michiaki Hiroe
Mild hypoxia induces hypertrophy of cultured neonatal rat cardiomyocytes: a possible endogenous endothelin-1-mediated mechanism.
Journal of molecular and cellular cardiology 1996;28(6):1271-7.
1996: H Akimoto; Hiroshi Ito; M Tanaka; Susumu Adachi; M Hata; M Lin; H Fujisaki; Fumiaki Marumo; Michiaki Hiroe
Heparin and heparan sulfate block angiotensin II-induced hypertrophy in cultured neonatal rat cardiomyocytes. A possible role of intrinsic heparin-like molecules in regulation of cardiomyocyte hypertrophy.
Circulation 1996;93(4):810-6.
1996: M Tamamori; Hiroshi Ito; Susumu Adachi; H Akimoto; Fumiaki Marumo; Michiaki Hiroe
Endothelin-3 induces hypertrophy of cardiomyocytes by the endogenous endothelin-1-mediated mechanism.
The Journal of clinical investigation 1996;97(2):366-72.
1995: H Fujisaki; Hiroshi Ito; Yasunobu Hirata; M Tanaka; M Hata; M Lin; Susumu Adachi; H Akimoto; Fumiaki Marumo; Michiaki Hiroe
Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression.
The Journal of clinical investigation 1995;96(2):1059-65.
1995: Susumu Adachi; Hiroshi Ito; Y Ohta; M Tanaka; Shigeru Ishiyama; M Nagata; Tetsuya Toyozaki; Yasunobu Hirata; Fumiaki Marumo; Michiaki Hiroe
Distribution of mRNAs for natriuretic peptides in RV hypertrophy after pulmonary arterial banding.
The American journal of physiology 1995;268(1 Pt 2):H162-9.
1994: Susumu Adachi; Hiroshi Ito; H Akimoto; M Tanaka; H Fujisaki; Fumiaki Marumo; Michiaki Hiroe
Insulin-like growth factor-II induces hypertrophy with increased expression of muscle specific genes in cultured rat cardiomyocytes.
Journal of molecular and cellular cardiology 1994;26(7):789-95.
1994: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; H Fujisaki; Susumu Adachi; H Akimoto; Y Ohta; Fumiaki Marumo
Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload.
Circulation 1994;89(5):2198-203.
1993: Hiroshi Ito; Yasunobu Hirata; Susumu Adachi; M Tanaka; M Tsujino; A Koike; Akihiko Nogami; F Murumo; Michiaki Hiroe
Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.
The Journal of clinical investigation 1993;92(1):398-403.
1993: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; M Tsujino; Susumu Adachi; Masayoshi Shichiri; A Koike; Akihiko Nogami; Fumiaki Marumo
Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes.
Circulation 1993;87(5):1715-21.
1992: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; Susumu Adachi; M Tujino; Fumiaki Marumo
[Endothelin-1 as an autocrine factor in hypertrophy of cardiomyocytes].
Japanese circulation journal 1992;56 Suppl 5():1314-8.