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Masahisa Jinushi

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Muhammad Baghdadi; Hirotoshi Dosaka-Akita; Hiroko Nagao; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Masahisa Jinushi
Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas.
Hisashi Iizasa; Masahisa Jinushi; Asuka Nanbo; Jun Nishikawa; Hironori Yoshiyama
Epstein-Barr Virus (EBV)-associated gastric carcinoma.
Shigeki Chiba; John D Colgan; Hirotoshi Dosaka-Akita; Yoichiro Fujioka; Jacob V Gorman; Mitsuomi Hirashima; Ichiro Kinoshita; Yusuke Ohba; Akinori Takaoka; Toshimitsu Uede; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Muhammad Baghdadi; Masahisa Jinushi
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.

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2013: Muhammad Baghdadi; Hirotoshi Dosaka-Akita; Hiroko Nagao; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Masahisa Jinushi
Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas.
Cancer immunology, immunotherapy : CII 2013;62(4):629-37.
2012: Hisashi Iizasa; Masahisa Jinushi; Asuka Nanbo; Jun Nishikawa; Hironori Yoshiyama
Epstein-Barr Virus (EBV)-associated gastric carcinoma.
Viruses 2012;4(12):3420-39.
2012: Shigeki Chiba; John D Colgan; Hirotoshi Dosaka-Akita; Yoichiro Fujioka; Jacob V Gorman; Mitsuomi Hirashima; Ichiro Kinoshita; Yusuke Ohba; Akinori Takaoka; Toshimitsu Uede; Hideo Yagita; Hironori Yoshiyama; Hisaya Akiba; Muhammad Baghdadi; Masahisa Jinushi
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.
Nature immunology 2012;13(9):832-42.
2012: Masahisa Jinushi; Muhammad Baghdadi; Shigeki Chiba; Hironori Yoshiyama
Regulation of cancer stem cell activities by tumor-associated macrophages.
American journal of cancer research 2012;2(5):529-39.
2012: Muhammad Baghdadi; Shigeki Chiba; Tsunaki Yamashina; Hironori Yoshiyama; Masahisa Jinushi
MFG-E8 regulates the immunogenic potential of dendritic cells primed with necrotic cell-mediated inflammatory signals.
PloS one 2012;7(6):e39607.
2010: Jonathan Schoenfeld; Masahisa Jinushi; Yukoh Nakazaki; Daniel Wiener; Joosang Park; Robert J Soiffer; Donna Neuberg; Martin Mihm; F Stephen Hodi; Glenn Dranoff
Active immunotherapy induces antibody responses that target tumor angiogenesis.
Cancer research 2010;70(24):10150-60.
2008: Masahisa Jinushi; Yukoh Nakazaki; Daniel R Carrasco; Dobrin Draganov; Nicholas Souders; Matthew Johnson; Martin C Mihm; Glenn Dranoff
Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment.
Cancer research 2008;68(21):8889-98.
2008: Masahisa Jinushi; F Stephen Hodi; Glenn Dranoff
Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines.
Immunological reviews 2008;222():287-98.
2008: Masahisa Jinushi; Matthew Vanneman; Nikhil C Munshi; Yu-Tzu Tai; Rao H Prabhala; Jerome Ritz; Donna Neuberg; Kenneth C Anderson; Daniel R Carrasco; Glenn Dranoff
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1285-90.
2007: Norimoto Kobayashi; Piia Karisola; Victor Peña-Cruz; David M Dorfman; Masahisa Jinushi; Sarah E Umetsu; Manish J Butte; Haruo Nagumo; Irina Chernova; Baogong Zhu; Arlene H Sharpe; Susumu Ito; Glenn Dranoff; Gerardo G Kaplan; José M Casasnovas; Dale T Umetsu; Rosemarie H Dekruyff; Gordon J Freeman
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
Immunity 2007;27(6):927-40.
2007: Masahisa Jinushi; Glenn Dranoff
Triggering tumor immunity through angiogenesis targeting.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(13):3762-4.
2007: Masahisa Jinushi; Yukoh Nakazaki; Michael Dougan; Daniel R Carrasco; Martin Mihm; Glenn Dranoff
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.
The Journal of clinical investigation 2007;117(7):1902-13.
2007: Tomohide Tatsumi; Tetsuo Takehara; Shinjiro Yamaguchi; A Sasakawa; Takuya Miyagi; Masahisa Jinushi; Ryotaro Sakamori; Keisuke Kohga; Akio Uemura; Kazuyoshi Ohkawa; Walter J Storkus; Norio Hayashi
Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.
Gene therapy 2007;14(11):863-71.
2007: Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Shinjiro Yamaguchi; Ryotaro Sakamori; Naoki Hiramatsu; Tatsuya Kanto; Kazuyoshi Ohkawa; Norio Hayashi
Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities.
Immunology 2007;120(1):73-82.
2006: Masahisa Jinushi; F Stephen Hodi; Glenn Dranoff
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9190-5.
2006: Tetsuo Takehara; Takahiro Suzuki; Kazuyoshi Ohkawa; Atsushi Hosui; Masahisa Jinushi; Takuya Miyagi; Tomohide Tatsumi; Yoshiyuki Kanazawa; Norio Hayashi
Viral covalently closed circular DNA in a non-transgenic mouse model for chronic hepatitis B virus replication.
Journal of hepatology 2006;44(2):267-74.
2005: Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Naoki Hiramatsu; Ryotaro Sakamori; Shinjiro Yamaguchi; Norio Hayashi
Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.
Journal of hepatology 2005;43(6):1013-20.
2004: Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Tatsuya Kanto; Takuya Miyagi; Takahiro Suzuki; Yoshiyuki Kanazawa; Naoki Hiramatsu; Norio Hayashi
Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6072-81.
2004: Takuya Miyagi; Tetsuo Takehara; Tomohide Tatsumi; Takahiro Suzuki; Masahisa Jinushi; Yoshiyuki Kanazawa; Naoki Hiramatsu; Tatsuya Kanto; Shingo Tsuji; Masatsugu Hori; Norio Hayashi
Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver.
Hepatology (Baltimore, Md.) 2004;40(5):1190-6.
2004: Tetsuo Takehara; Tomohide Tatsumi; Takahiro Suzuki; Edmund B Rucker; Lothar Hennighausen; Masahisa Jinushi; Takuya Miyagi; Yoshiyuki Kanazawa; Norio Hayashi
Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.
Gastroenterology 2004;127(4):1189-97.
2003: Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Tatsuya Kanto; Veronika Groh; Thomas Spies; Takahiro Suzuki; Takuya Miyagi; Norio Hayashi
Autocrine/paracrine IL-15 that is required for type I IFN-mediated dendritic cell expression of MHC class I-related chain A and B is impaired in hepatitis C virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5423-9.
2003: Takuya Miyagi; Tetsuo Takehara; Tomohide Tatsumi; Tatsuya Kanto; Takahiro Suzuki; Masahisa Jinushi; Yoshiko Sugimoto; Yutaka Sasaki; Masatsugu Hori; Norio Hayashi
CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver.
International journal of cancer. Journal international du cancer 2003;106(1):81-9.
2003: Masahisa Jinushi; Tetsuo Takehara; Tomohide Tatsumi; Tatsuya Kanto; Veronika Groh; Thomas Spies; Ritsuko Kimura; Takuya Miyagi; Kiyoshi Mochizuki; Yutaka Sasaki; Norio Hayashi
Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid.
International journal of cancer. Journal international du cancer 2003;104(3):354-61.
2003: Masahisa Jinushi; Tetsuo Takehara; Tatsuya Kanto; Tomohide Tatsumi; Veronika Groh; Thomas Spies; Takuya Miyagi; Takahiro Suzuki; Yutaka Sasaki; Norio Hayashi
Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1249-56.
2003: Takahiro Suzuki; Tetsuo Takehara; Kazuyoshi Ohkawa; Hisashi Ishida; Masahisa Jinushi; Takuya Miyagi; Yutaka Sasaki; Norio Hayashi
Intravenous injection of naked plasmid DNA encoding hepatitis B virus (HBV) produces HBV and induces humoral immune response in mice.
Biochemical and biophysical research communications 2003;300(3):784-8.
2003: Takuya Miyagi; Tomohide Tatsumi; Tetsuo Takehara; Tatsuya Kanto; Noriyoshi Kuzushita; Yoshiko Sugimoto; Masahisa Jinushi; Akinori Kasahara; Yutaka Sasaki; Masatsugu Hori; Norio Hayashi
Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells.
Journal of gastroenterology and hepatology 2003;18(1):32-40.
2002: Y Sugimoto; Noriyoshi Kuzushita; Tetsuo Takehara; Tatsuya Kanto; Tomohide Tatsumi; Takuya Miyagi; Masahisa Jinushi; Kazuyoshi Ohkawa; Masayoshi Horimoto; Akinori Kasahara; Masatsugu Hori; Yutaka Sasaki; Norio Hayashi
A single nucleotide polymorphism of the low molecular mass polypeptide 7 gene influences the interferon response in patients with chronic hepatitis C.
Journal of viral hepatitis 2002;9(5):377-84.
2001: Tomohide Tatsumi; Tetsuo Takehara; Tatsuya Kanto; Takuya Miyagi; Noriyoshi Kuzushita; Yukihiko Sugimoto; Masahisa Jinushi; Akinori Kasahara; Yutaka Sasaki; Masatsugu Hori; Norio Hayashi
Administration of interleukin-12 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines in mouse hepatocellular carcinoma.
Cancer research 2001;61(20):7563-7.