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Christian Jobin

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Janelle C Arthur; Christian Jobin
The complex interplay between inflammation, the microbiota and colorectal cancer.
Javier Rivera Guzman; Ja-Seol Koo; Marcus Mühlbauer; Acharan Narula; Jason R Goldsmith; Christian Jobin
Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation.
Christian Jobin
Colorectal cancer: looking for answers in the microbiota.

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All Publications

2013: Janelle C Arthur; Christian Jobin
The complex interplay between inflammation, the microbiota and colorectal cancer.
Gut microbes 2013;4(3):253-8.
2013: Javier Rivera Guzman; Ja-Seol Koo; Marcus Mühlbauer; Acharan Narula; Jason R Goldsmith; Christian Jobin
Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation.
Scientific reports 2013;3():1629.
2013: Christian Jobin
Colorectal cancer: looking for answers in the microbiota.
Cancer discovery 2013;3(4):384-7.
2013: Jason R Goldsmith; Ernesto Perez-Chanona; Bryan Roth; Jennifer Whistler; Prem N Yadav; Christian Jobin
Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling.
The American journal of pathology 2013;182(3):776-85.
2013: Javier Rivera Guzman; Victoria Susan Conlin; Christian Jobin
Diet, microbiome, and the intestinal epithelium: an essential triumvirate?
BioMed research international 2013;2013():425146.
2013: Xiaolun Sun; Bo Liu; Ryan Balfour Sartor; Christian Jobin
Phosphatidylinositol 3-kinase-γ signaling promotes Campylobacter jejuni-induced colitis through neutrophil recruitment in mice.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(1):357-65.
2013: Jason R Goldsmith; Jordan L Cocchiaro; John F Rawls; Christian Jobin
Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses.
Disease models & mechanisms 2013;6(1):146-59.
2012: Christian Jobin
Colorectal cancer: CRC--all about microbial products and barrier function?
Nature reviews. Gastroenterology & hepatology 2012;9(12):694-6.
2012: Janelle C Arthur; Barry J Campbell; Belgin Dogan; Ting-Jia Fan; Anthony A Fodor; Jonathan J Hansen; Turki Abujamel; Temitope Keku; Marcus Mühlbauer; Ernesto Perez-Chanona; Jonathan M Rhodes; Arlin B Rogers; Kenneth W Simpson; Alain Stintzi; Sarah Tomkovich; Joshua M Uronis; Christian Jobin
Intestinal inflammation targets cancer-inducing activity of the microbiota.
Science (New York, N.Y.) 2012;338(6103):120-3.
2012: Irving C Allen; Janelle C Arthur; Beckley K Davis; Hans H Herfarth; Christian Jobin; John David Lich; Reid A Roberts; Arlin B Rogers; Monika Schneider; Joshua M Uronis; Justin E Wilson; Rita-Marie T Woodford; Jenny P-Y Ting
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.
Immunity 2012;36(5):742-54.
2012: J R Goldsmith; Christian Jobin
Think small: zebrafish as a model system of human pathology.
Journal of biomedicine & biotechnology 2012;2012():817341.
2012: Houda Z Elloumi; Christian Jobin; Taku Kobayashi; Fengling Li; Nitsan Maharshak; Marcus Mühlbauer; Kavitha N Rao; Hyungjin S Ryu; Scott Plevy
A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis.
PloS one 2012;7(3):e34172.
2012: Ajay S Gulati; Susan J Henning; Christian Jobin; Lieselotte Kreuk; Janelle C Arthur; Emily Grossniklaus; Michael T Shanahan; Richard J von Furstenberg; R Balfour Sartor
Mouse background strain profoundly influences Paneth cell function and intestinal microbial composition.
PloS one 2012;7(2):e32403.
2012: Josep Bassaganya-Riera; Adria Carbo; Benjamin A Corl; Claudio De Simone; Christian Jobin; Mireia Pedragosa; Rustem Shaykhutdinov; Martin Storr; Monica Viladomiu; Hans Vogel; Janelle C Arthur; Raquel Hontecillas
Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis.
PloS one 2012;7(2):e31238.
2011: Caroline B Appleyard; Janelle C Arthur; Myrella L Cruz; Angel A Isidro; Christian Jobin; Claudio De Simone
Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer.
American journal of physiology. Gastrointestinal and liver physiology 2011;301(6):G1004-13.
2011: Michelle Kanther; Lantz C Mackey; Marcus Mühlbauer; Michel Bagnat; Edward J Flynn; Christian Jobin; Xiaolun Sun; John F Rawls
Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.
Gastroenterology 2011;141(1):197-207.
2011: Thomas Karrasch; Tanja Spaeth; Brigitte Allard; Christian Jobin
PI3K-dependent GSK3ß(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response.
PloS one 2011;6(10):e26340.
2011: Janelle C Arthur; Christian Jobin
The struggle within: microbial influences on colorectal cancer.
Inflammatory bowel diseases 2011;17(1):396-409.
2011: Joshua M Uronis; Janelle C Arthur; Temitope Keku; Anthony Fodor; Ian Carroll; Myrella L Cruz; Caroline B Appleyard; Christian Jobin
Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS-induced colitis.
Inflammatory bowel diseases 2011;17(1):289-97.
2010: Bret D Wallace; Hongwei Wang; Kimberly T Lane; John E Scott; Jillian Orans; Ja-Seol Koo; Madhukumar Venkatesh; Christian Jobin; Li-An Yeh; venkatesh madhukumar; Matthew R Redinbo
Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.
Science (New York, N.Y.) 2010;330(6005):831-5.
2010: Christian Jobin
MyD88 signaling in the intestine: Dr Jekyll and Mr Hyde?
Gastroenterology 2010;139(2):383-5.
2010: Irving C Allen; Erin McElvania TeKippe; Rita-Marie T Woodford; Joshua M Uronis; Eda K Holl; Arlin B Rogers; Hans H Herfarth; Christian Jobin; Jenny P-Y Ting
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.
The Journal of experimental medicine 2010;207(5):1045-56.
2010: Christian Jobin
Probiotics and ileitis: could augmentation of TNF/NFκB activity be the answer?
Gut microbes 2010;1(3):196-9.
2010: Robert D Thurston; Claire B Larmonier; Pawel M Majewski; Rajalakshmy Ramalingam; Monica Midura-Kiela; Daniel Laubitz; Alain Vandewalle; David G Besselsen; Marcus Mühlbauer; Christian Jobin; Pawel Kiela; Fayez K Ghishan
Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis.
Gastroenterology 2010;138(4):1384-94, 1394.e1-2.
2010: Shengli Ding; Michael M Chi; Brooks P Scull; Rachael Rigby; Nicole M J Schwerbrock; Scott Magness; Christian Jobin; Pauline K Lund
High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse.
PloS one 2010;5(8):e12191.
2009: T Karrasch; Christian Jobin
Wound healing responses at the gastrointestinal epithelium: a close look at novel regulatory factors and investigative approaches.
Zeitschrift für Gastroenterologie 2009;47(12):1221-9.
2009: J M Uronis; Christian Jobin
Microbes and colorectal cancer: is there a relationship?
Current oncology (Toronto, Ont.) 2009;16(4):22-4.
2009: Elisabeth Lippert; Thomas Karrasch; Xiaolun Sun; Brigitte Allard; Hans Herfarth; Deborah Threadgill; Christian Jobin
Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection.
PloS one 2009;4(10):e7413.
2009: Joshua M Uronis; Marcus Mühlbauer; Hans Herfarth; Tara C Rubinas; Gieira S Jones; Christian Jobin
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.
PloS one 2009;4(6):e6026.
2009: Young-Eun Joo; Thomas Karrasch; Marcus Mühlbauer; Brigitte Allard; Acharan Narula; Hans Herfarth; Christian Jobin
Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice.
PloS one 2009;4(2):e4562.
2009: Jae-Young Kim; Rie Kajino-Sakamoto; Emily Omori; Christian Jobin; Jun Ninomiya-Tsuji
Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis.
PloS one 2009;4(2):e4561.
2008: Claire B Larmonier; J K Uno; Kang-Moon Lee; T Karrasch; D Laubitz; R Thurston; M T Midura-Kiela; Fayez K Ghishan; Ryan Sartor; Christian Jobin; Pawel Kiela
Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(5):G1079-91.
2008: Carine Chavey; Marcus Mühlbauer; Carine Bossard; Ariane Freund; Sébastien Durand; Christian Jorgensen; Christian Jobin; Gwendal Lazennec
Interleukin-8 expression is regulated by histone deacetylases through the nuclear factor-kappaB pathway in breast cancer.
Molecular pharmacology 2008;74(5):1359-66.
2008: Christian Jobin
Nf-kappa B signaling cascade and IBD: turn it down?
Inflammatory bowel diseases 2008;14 Suppl 2():S108-9.
2008: Rie Kajino-Sakamoto; Maiko Inagaki; Elisabeth Lippert; Shizuo Akira; Sylvie Robine; Kunihiro Matsumoto; Christian Jobin; Jun Ninomiya-Tsuji
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1143-52.
2008: Marcus Mühlbauer; Adam W Cheely; yenugu suresh; Christian Jobin
Regulation and functional impact of lipopolysaccharide induced Nod2 gene expression in the murine epididymal epithelial cell line PC1.
Immunology 2008;124(2):256-64.
2008: Marcus Mühlbauer; Paula M Chilton; Thomas C Mitchell; Christian Jobin
Impaired Bcl3 up-regulation leads to enhanced lipopolysaccharide-induced interleukin (IL)-23P19 gene expression in IL-10(-/-) mice.
The Journal of biological chemistry 2008;283(21):14182-9.
2008: Catherine P A Ivory; Michael Prystajecky; Christian Jobin; Kris Chadee
Toll-like receptor 9-dependent macrophage activation by Entamoeba histolytica DNA.
Infection and immunity 2008;76(1):289-97.
2008: Thomas Karrasch; Christian Jobin
NF-kappaB and the intestine: friend or foe?
Inflammatory bowel diseases 2008;14(1):114-24.
2007: Shaival H Davé; Jeremy S Tilstra; Katsuyoshi Matsuoka; Fengling Li; Thomas Karrasch; Jennifer K Uno; Antonia R Sepulveda; Christian Jobin; Albert S Baldwin; Paul D Robbins; Scott Plevy
Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7852-9.
2007: Sandra Kim; Susan L Tonkonogy; Thomas Karrasch; Christian Jobin; Ryan Sartor
Dual-association of gnotobiotic IL-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis.
Inflammatory bowel diseases 2007;13(12):1457-66.
2007: Thomas Karrasch; Joo-Sung Kim; Marcus Muhlbauer; Scott T Magness; Christian Jobin
Gnotobiotic IL-10-/-;NF-kappa B(EGFP) mice reveal the critical role of TLR/NF-kappa B signaling in commensal bacteria-induced colitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6522-32.
2007: Thomas Karrasch; Joo-Sung Kim; Byung Ik Jang; Christian Jobin
The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules.
PloS one 2007;2(7):e596.
2006: Thomas Karrasch; Kris A Steinbrecher; Brigitte Allard; Albert S Baldwin; Christian Jobin
Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes.
Journal of cellular physiology 2006;207(3):809-15.
2005: Cormac Taylor; Christian Jobin
Ubiquitin protein modification and signal transduction: implications for inflammatory bowel diseases.
Inflammatory bowel diseases 2005;11(12):1097-107.
2005: Arianne L Theiss; James G Simmons; Christian Jobin; P Kay Lund
Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2.
The Journal of biological chemistry 2005;280(43):36099-109.
2005: Humberto B Jijon; John Walker; Frank Hoentjen; Hugo Diaz; Julia B Ewaschuk; Christian Jobin; Karen L Madsen
Adenosine is a negative regulator of NF-kappaB and MAPK signaling in human intestinal epithelial cells.
Cellular immunology 2005;237(2):86-95.
2005: Sen Rong Yan; Robbie Randle Joseph; Kirill Rosen; Mauricio J Reginato; Amanda Jackson; Norman Allaire; Joan S Brugge; Christian Jobin; Andrew W Stadnyk
Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells.
Oncogene 2005;24(43):6482-91.
2005: J S Kim; A S Narula; Christian Jobin
Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kappaB signalling in intestinal epithelial cells.
Clinical and experimental immunology 2005;141(2):288-97.
2005: Dawei Ou; Xiaojie Wang; Daniel L Metzger; M Robbins; Junqi Huang; Christian Jobin; Janet Kathleen Chantler; Roger F L James; Paolo Pozzilli; Aubrey J Tingle
Regulation of TNF-related apoptosis-inducing ligand-mediated death-signal pathway in human beta cells by Fas-associated death domain and nuclear factor kappaB.
Human immunology 2005;66(7):799-809.
2005: Heather M Wilson; Salah Chettibi; Christian Jobin; David Walbaum; Andrew J Rees; David C Kluth
Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo.
The American journal of pathology 2005;167(1):27-37.
2005: Joo Sung Kim; Christian Jobin
The flavonoid luteolin prevents lipopolysaccharide-induced NF-kappaB signalling and gene expression by blocking IkappaB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells.
Immunology 2005;115(3):375-87.
2005: Humberto B Jijon; Karen L Madsen; John W Walker; Brigitte Allard; Christian Jobin
Serum amyloid A activates NF-kappaB and proinflammatory gene expression in human and murine intestinal epithelial cells.
European journal of immunology 2005;35(3):718-26.
2005: Frank Hoentjen; Ryan Sartor; Michitaka Ozaki; Christian Jobin
STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells.
Blood 2005;105(2):689-96.
2004: Silke Kuphal; Ina Poser; Christian Jobin; Claus Hellerbrand; Anja Bosserhoff
Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma.
Oncogene 2004;23(52):8509-19.
2004: Humberto B Jijon; Brigitte Allard; Christian Jobin
NF-kappaB inducing kinase activates NF-kappaB transcriptional activity independently of IkappaB kinase gamma through a p38 MAPK-dependent RelA phosphorylation pathway.
Cellular signalling 2004;16(9):1023-32.
2004: Scott T Magness; Humberto B Jijon; Nancy Van Houten Fisher; Norman E Sharpless; David A Brenner; Christian Jobin
In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1561-70.
2004: Dirk Haller; L Holt; Alexandr Parlesak; J Zanga; A Bäuerlein; Ryan Sartor; Christian Jobin
Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells.
Immunology 2004;112(2):310-20.
2004: Maria P Russo; Robert F Schwabe; Ryan Sartor; Christian Jobin
NF-kappaB-inducing kinase restores defective IkappaB kinase activity and NF-kappaB signaling in intestinal epithelial cells.
Cellular signalling 2004;16(6):741-50.
2004: Marcus Mühlbauer; Brigitte Allard; Anja Bosserhoff; Stephan Kiessling; Hans Herfarth; Gerhard Rogler; Jurgen Schölmerich; Christian Jobin; Claus Hellerbrand
Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(6):G1000-8.
2004: Patrick Laprise; Marie-Josée Langlois; Marie-Josée Boucher; Christian Jobin; Nathalie Rivard
Down-regulation of MEK/ERK signaling by E-cadherin-dependent PI3K/Akt pathway in differentiating intestinal epithelial cells.
Journal of cellular physiology 2004;199(1):32-9.
2004: Dirk Haller; Christian Jobin
Interaction between resident luminal bacteria and the host: can a healthy relationship turn sour?
Journal of pediatric gastroenterology and nutrition 2004;38(2):123-36.
2004: Joo-Sung Kim; Christian Jobin
Role of NF-kappaB in inflammatory disorders: just when you thought you knew everything!
Journal of pediatric gastroenterology and nutrition 2004;38(1):109-10.
2003: Dirk Haller; Lisa Holt; Sandra Kim; Robert F Schwabe; Ryan Sartor; Christian Jobin
Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation.
The Journal of biological chemistry 2003;278(26):23851-60.
2003: Yong Han Paik; Robert F Schwabe; Ramón Bataller; Maria P Russo; Christian Jobin; David A Brenner
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells.
Hepatology (Baltimore, Md.) 2003;37(5):1043-55.
2003: Christian Jobin
Intestinal epithelial cells and innate immunity in the intestine: is CARD15/Nod2 another player?
Gastroenterology 2003;124(4):1145-9.
2003: Ulrich Böcker; T Nebe; Frank Herweck; L Holt; Asit Panja; Christian Jobin; Siegbert Rossol; R B Sartor; Manfred V Singer
Butyrate modulates intestinal epithelial cell-mediated neutrophil migration.
Clinical and experimental immunology 2003;131(1):53-60.
2002: Dirk Haller; Maria P Russo; Ryan Sartor; Christian Jobin
IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines.
The Journal of biological chemistry 2002;277(41):38168-78.
2002: Asha L Bhakar; Laura-Lee Tannis; Christine Zeindler; Maria P Russo; Christian Jobin; David Park; Sandra MacPherson; Philip A Barker
Constitutive nuclear factor-kappa B activity is required for central neuron survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(19):8466-75.
2002: Maria P Russo; Brydon L Bennett; Anthony Manning; David A Brenner; Christian Jobin
Differential requirement for NF-kappaB-inducing kinase in the induction of NF-kappaB by IL-1beta, TNF-alpha, and Fas.
American journal of physiology. Cell physiology 2002;283(1):C347-57.
2001: Harry Heimberg; Yves Heremans; Christian Jobin; R Leemans; Alessandra K Cardozo; Martine I Darville; Decio L Eizirik
Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.
Diabetes 2001;50(10):2219-24.
2001: Xian-Ming Chen; S A Levine; Patrick L Splinter; Pamela S Tietz; A L Ganong; Christian Jobin; Gregory J Gores; Carlos V Paya; Nicholas F LaRusso
Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis.
Gastroenterology 2001;120(7):1774-83.
2001: Sean A Weaver; Maria P Russo; Karen Wright; George Kolios; Christian Jobin; Duncan A F Robertson; Stephen G Ward
Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells.
Gastroenterology 2001;120(5):1117-27.
2000: Alston E Dunbar; Susan E Wert; M Ikegami; Jeffrey A Whitsett; Aaron Hamvas; Frances V White; B Piedboeuf; Christian Jobin; Susan H Guttentag; Lawrence M Nogee
Prolonged survival in hereditary surfactant protein B (SP-B) deficiency associated with a novel splicing mutation.
Pediatric research 2000;48(3):275-82.
2000: Christian Jobin; Ryan Sartor
NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases.
Inflammatory bowel diseases 2000;6(3):206-13.
2000: Ulrich Böcker; Arndt Schottelius; Joanna M Watson; L Holt; LL Licato; David A Brenner; Ryan Sartor; Christian Jobin
Cellular differentiation causes a selective down-regulation of interleukin (IL)-1beta-mediated NF-kappaB activation and IL-8 gene expression in intestinal epithelial cells.
The Journal of biological chemistry 2000;275(16):12207-13.
2000: Christian Jobin; Ryan Sartor
The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection.
American journal of physiology. Cell physiology 2000;278(3):C451-62.
1999: Christian Jobin; Cynthia A Bradham; Maria P Russo; B Juma; A S Narula; David A Brenner; Ryan Sartor
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3474-83.
1999: Christian Jobin; L Holt; Cynthia A Bradham; K Streetz; David A Brenner; Ryan Sartor
TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4447-54.
1999: Christian Jobin; Kevin E Behrns; David A Brenner
Molecular and cellular biology of the small intestine.
Current opinion in gastroenterology 1999;15(2):103-7.
1999: X C Wang; Christian Jobin; Janice B Allen; Wendy L Roberts; Glenn J Jaffe
Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
Investigative ophthalmology & visual science 1999;40(2):477-86.
1998: Christian Jobin; O Morteau; D S Han; R Balfour Sartor
Specific NF-kappaB blockade selectively inhibits tumour necrosis factor-alpha-induced COX-2 but not constitutive COX-1 gene expression in HT-29 cells.
Immunology 1998;95(4):537-43.
1998: Ulrich Böcker; A Damião; L Holt; D S Han; Christian Jobin; Asit Panja; L Mayer; Ryan Sartor
Differential expression of interleukin 1 receptor antagonist isoforms in human intestinal epithelial cells.
Gastroenterology 1998;115(6):1426-38.
1998: Claus Hellerbrand; Christian Jobin; LL Licato; Ryan Sartor; David A Brenner
Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells.
The American journal of physiology 1998;275(2 Pt 1):G269-78.
1998: Christian Jobin; Claus Hellerbrand; LL Licato; David A Brenner; Ryan Sartor
Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors.
Gut 1998;42(6):779-87.
1998: Claus Hellerbrand; Christian Jobin; Yuji Iimuro; LL Licato; Ryan Sartor; David A Brenner
Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor.
Hepatology (Baltimore, Md.) 1998;27(5):1285-95.
1998: Christian Jobin; Asit Panja; Claus Hellerbrand; Yuji Iimuro; J Didonato; David A Brenner; Ryan Sartor
Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):410-8.
1997: Christian Jobin; J Gauthier
Differential effects of cell density on 5-lipoxygenase (5-LO), five-lipoxygenase-activating protein (FLAP) and interleukin-1 beta (IL-1 beta) expression in human neutrophils.
Inflammation 1997;21(2):235-50.
1997: Christian Jobin; Stephen J Haskill; L Mayer; Asit Panja; Ryan Sartor
Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):226-34.
1991: Christian Jobin; C Kreis; J Gauthier; J Letarte; A D Beaulieu
Differential synthesis of 5-lipoxygenase in peripheral blood and synovial fluid neutrophils in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(8):2701-7.