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Jan Baak

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Disorders

Phenomena

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Cell Nucleus

Activities & Behaviors

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Disease Progression

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Co-Publications
Name
84
van Diest, Paul
39
Janssen, Emiel
35
Meijer, Gerrit
23
Skaland, Ivar
22
Meijer, Chris
21
Hermsen, Mario
20
gudlaugsson, einar
17
Kruse, Arnold-Jan
15
Kjellevold, Kjell
13
Beliën, Jeroen
13
van Diermen, Bianca
12
Søiland, Håvard
10
Søreide, Jon Arne
10
Bergers, E
10
Brinkhuis, M

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Publications

TOP 3
Baak Jan P A; Gudlaugsson Einar; Skaland Ivar; Guo Lydia Hui Ru; Klos Jan; Lende Tone Hoel; Søiland Håvard; Janssen Emiel A M; Zur Hausen Axel
Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers.
Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Klos Jan; Kjellevold Kjell H; Søiland Håvard; Baak Jan P A
Validating the prognostic value of proliferation measured by Phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients less than 71 years of age.
Lin Ming-Chieh; Lomo Lesley; Baak Jan P A; Eng Charis; Ince Tan A; Crum Christopher P; Mutter George L
Squamous morules are functionally inert elements of premalignant endometrial neoplasia.

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All Publications

2009: Baak Jan P A; Gudlaugsson Einar; Skaland Ivar; Guo Lydia Hui Ru; Klos Jan; Lende Tone Hoel; Søiland Håvard; Janssen Emiel A M; Zur Hausen Axel
Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers.
Breast cancer research and treatment 2009;115(2):241-54.
2009: Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Klos Jan; Kjellevold Kjell H; Søiland Håvard; Baak Jan P A
Validating the prognostic value of proliferation measured by Phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients less than 71 years of age.
Breast cancer research and treatment 2009;114(1):39-45.
2009: Lin Ming-Chieh; Lomo Lesley; Baak Jan P A; Eng Charis; Ince Tan A; Crum Christopher P; Mutter George L
Squamous morules are functionally inert elements of premalignant endometrial neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(2):167-74.
2009: Søiland Håvard; Janssen Emiel A M; Kørner Hartwig; Varhaug Jan Erik; Skaland Ivar; Gudlaugsson Einar; Baak Jan P A; Søreide Jon Arne
Apolipoprotein D predicts adverse outcome in women >or=70 years with operable breast cancer.
Breast cancer research and treatment 2009;113(3):519-28.
2009: Søreide Kjetil; Slewa Aida; Stokkeland Pål J; van Diermen Bianca; Janssen Emiel A M; Søreide Jon Arne; Baak Jan P A; Kørner Hartwig
Microsatellite instability and DNA ploidy in colorectal cancer: potential implications for patients undergoing systematic surveillance after resection.
Cancer 2009;115(2):271-82.
2009: Steinbakk Anita; Skaland Ivar; Gudlaugsson Einar; Janssen Emiel A M; Kjellevold Kjell H; Klos Jan; Løvslett Kjell; Fiane Bent; Baak Jan P A
The prognostic value of molecular biomarkers in tissue removed by curettage from FIGO stage 1 and 2 endometrioid type endometrial cancer.
American journal of obstetrics and gynecology 2009;200(1):78.e1-8.
2009: Janssen Emiel A M; Øvestad Irene T; Skaland Ivar; Søiland Håvard; Gudlaugsson Einar; Kjellevold Kjell H; Nysted Arne; Søreide Jon-Arne; Baak Jan P A
LOH at 1p31 (ARHI) and proliferation in lymph node-negative breast cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2009;31(5):335-43.
2009: Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Hui Ru Guo Lydia; Baak Jan P A
The prognostic value of the proliferation marker phosphohistone H3 (PPH3) in luminal, basal-like and triple negative phenotype invasive lymph node-negative breast cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2009;31(4):261-71.
2009: Søiland Håvard; Skaland Ivar; Varhaug Jan Erik; Kørner Hartwig; Janssen Emiel A M; Gudlaugsson Einar; Baak Jan P A; Søreide Jon Arne
Co-expression of estrogen receptor alpha and Apolipoprotein D in node positive operable breast cancer--possible relevance for survival and effects of adjuvant tamoxifen in postmenopausal patients.
Acta oncologica (Stockholm, Sweden) 2009;48(4):514-21.
2008: Søiland Håvard; Kørner Hartwig; Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Varhaug Jan Erik; Baak Jan P A; Søreide Jon Arne
Prognostic relevance of androgen receptor detection in operable breast cancer.
Journal of surgical oncology 2008;98(7):551-8.
2008: Søiland Håvard; Skaland Ivar; van Diermen Bianca; Janssen Emiel A M; Körner Hartwig; Varhaug Jan Erik; Søreide Jon Arne; Baak Jan P A
Androgen receptor determination in breast cancer: a comparison of the dextran-coated charcoal method and quantitative immunohistochemical analysis.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2008;16(4):362-70.
2008: Mutter George L; Kauderer James; Baak Jan P A; Alberts David;
Biopsy histomorphometry predicts uterine myoinvasion by endometrial carcinoma: a Gynecologic Oncology Group study.
Human pathology 2008;39(6):866-74.
2008: Skaland Ivar; van Diest Paul J; Janssen Emiel A M; Gudlaugsson Einar; Baak Jan P A
Prognostic differences of World Health Organization-assessed mitotic activity index and mitotic impression by quick scanning in invasive ductal breast cancer patients younger than 55 years.
Human pathology 2008;39(4):584-90.
2008: Kruse Arnold-Jan; Skaland Ivar; Munk Ane Cecilie; Janssen Emiel; Gudlaugsson Einar; Baak Jan P A
Low p53 and retinoblastoma protein expression in cervical intraepithelial neoplasia grade 3 lesions is associated with coexistent adenocarcinoma in situ.
Human pathology 2008;39(4):573-8.
2008: Søreide Kjetil; Gudlaugsson Einar; Skaland Ivar; Janssen Emiel A M; Van Diermen Bianca; Körner Hartwig; Baak Jan P A
Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.
International journal of colorectal disease 2008;23(4):389-400.
2008: Baak J P A; van Diest P J; Janssen E A M; Gudlaugsson E; Voorhorst F J; van der Wall E; Vermorken J B;
Proliferation accurately identifies the high-risk patients among small, low-grade, lymph node-negative invasive breast cancers.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(4):649-54.
2008: Søiland Håvard; Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Körner Hartwig; Varhaug Jan Erik; Søreide Jon Arne; Baak Jan P A
Comparison of apolipoprotein D determination methods in breast cancer.
Anticancer research 2008;28(2B):1151-60.
2008: Skaland Ivar; Ovestad Irene; Janssen Emiel A M; Klos Jan; Kjellevold Kjell H; Helliesen Tove; Baak Jan P A
Digital image analysis improves the quality of subjective HER-2 expression scoring in breast cancer.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2008;16(2):185-90.
2008: Skaland I; Øvestad I; Janssen E A M; Klos J; Kjellevold K H; Helliesen T; Baak J P A
Comparing subjective and digital image analysis HER2/neu expression scores with conventional and modified FISH scores in breast cancer.
Journal of clinical pathology 2008;61(1):68-71.
2007: Munk Ane Cecilie; Kruse Arnold-Jan; van Diermen Bianca; Janssen Emiel A M; Skaland Ivar; Gudlaugsson Einar; Nilsen Stein Tore; Baak Jan P A
Cervical intraepithelial neoplasia grade 3 lesions can regress.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2007;115(12):1409-14.
2007: Skaland Ivar; Janssen Emiel A M; Gudlaugsson Einar; Klos Jan; Kjellevold Kjell H; Søiland Håvard; Baak Jan P A
Phosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients less than 55 years of age.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(12):1307-15.
2007: Oevestad Irene T; Janssen Emiel A M; Baak Jan P A
The effect of different DNA isolation methods on the outcome of high-risk HPV testing.
Indian journal of pathology & microbiology 2007;50(4):733-9.
2007: Kruse Arnold-Jan; Baak Jan P A
Re: "the expressions of the Rb pathway in cervical intraepithelial neoplasia: predictive and prognostic significance" by Nam et al.
Gynecologic oncology 2007;105(2):556-7; author reply 557-8.
2007: Mutter George L; Zaino Richard J; Baak Jan P A; Bentley Rex C; Robboy Stanley J
Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007;26(2):103-14.
2007: Baak Jan P A; van Diest Paul J; Voorhorst Feja J; van der Wall Elsken; Beex Louk V A M; Vermorken Jan B; Janssen Emiel A M; Gudlaugsson Einar;
The prognostic value of proliferation in lymph-node-negative breast cancer patients is age dependent.
European journal of cancer (Oxford, England : 1990) 2007;43(3):527-35.
2007: Baak Jan P A; Mohan Harsh
Genomics and proteomics in neoplasia.
Indian journal of pathology & microbiology 2007;50(1):1-5.
2007: Soreide Kjetil; Buter Tirza C E; Janssen Emiel A; Gudlaugsson Einar; Skaland Ivar; Körner Hartwig; Baak Jan P A
Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(4):301-13.
2007: Søiland Håvard; Søreide Kjetil; Janssen Emiel A M; Körner Hartwig; Baak Jan P A; Søreide Jon Arne
Emerging concepts of apolipoprotein D with possible implications for breast cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(3):195-209.
2007: Janssen Emiel A M; Søiland Håvard; Skaland Ivar; Gudlaugson Einar; Kjellevold Kjell H; Nysted Arne; Søreide Jon-Arne; Baak Jan P A
Comparing the prognostic value of PTEN and Akt expression with the Mitotic Activity Index in adjuvant chemotherapy-treated node-negative breast cancer patients aged <55 years.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(1):25-35.
2006: Baak J P A; Kruse A-J; Robboy S J; Janssen E A M; van Diermen B; Skaland I
Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers.
Journal of clinical pathology 2006;59(10):1017-28.
2006: Soreide Kjetil; Buter Tirza C E; Janssen Emiel A M; van Diermen Bianca; Baak Jan P A
A monotonous population of elongated cells (MPECs) in colorectal adenoma indicates a high risk of metachronous cancer.
The American journal of surgical pathology 2006;30(9):1120-9.
2006: Soreide K; Janssen E A; Körner H; Baak J P A
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
The Journal of pathology 2006;209(2):147-56.
2006: Söreide K; Janssen E A M; Söiland H; Körner H; Baak J P A
Microsatellite instability in colorectal cancer.
The British journal of surgery 2006;93(4):395-406.
2006: Mohan Harsh; Baak J P A
Morphometrical analysis in endometrial hyperplasia: predictive of progression to cancer.
Indian journal of pathology & microbiology 2006;49(1):21-2.
2006: Janssen Emiel A M; van Diest Paul J; Søiland Håvard; Gudlaugson Einar; Nysted Arne; Voorhorst Feja J; Vermorken Jan B; Søreide Jon-Arne; Baak Jan P A
Success predictors of adjuvant chemotherapy in node-negative breast cancer patients under 55 years.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(5-6):295-303.
2006: Baak Jan P A
Quantitative histopathological analysis of CIN sections.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(1-2):63-5; author reply 61-2.
2005: Hsu Chih-Yi; Kurman Robert J; Vang Russell; Wang Tian-Li; Baak Jan; Shih Ie-Ming
Nuclear size distinguishes low- from high-grade ovarian serous carcinoma and predicts outcome.
Human pathology 2005;36(10):1049-54.
2005: Baak Jan P A; Colpaert Cecile G A; van Diest Paul J; Janssen Emiel; van Diermen Bianca; Albernaz Eliza; Vermeulen Peter B; Van Marck Eric A
Multivariate prognostic evaluation of the mitotic activity index and fibrotic focus in node-negative invasive breast cancers.
European journal of cancer (Oxford, England : 1990) 2005;41(14):2093-101.
2005: Baak Jan P A; van Diest Paul J; Voorhorst Feja J; van der Wall Elsken; Beex Louk V A M; Vermorken Jan B; Janssen Emiel A M
Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(25):5993-6001.
2005: Baak Jan P A; Kruse Arnold-Jan; Garland Suzanne M; Skaland Ivar; Janssen Emiel A M; Tabrizi Sepehr; Fagerheim Siri; Robboy Stanley; Nilsen Stein-Tore
Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions.
The American journal of surgical pathology 2005;29(8):1062-6.
2005: Baak Jan P; Mutter George L; Robboy Stanley; van Diest Paul J; Uyterlinde Anne M; Orbo Anne; Palazzo Juan; Fiane Bent; Løvslett Kjell; Burger Curt; Voorhorst Feja; Verheijen René H
The molecular genetics and morphometry-based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia more accurately than the 1994 World Health Organization classification system.
Cancer 2005;103(11):2304-12.
2005: Baak Jan Pieter Albert; Van Diermen Bianca; Steinbakk Anita; Janssen Emiel; Skaland Ivar; Mutter George L; Fiane Bent; Løvslett Kjell
Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression.
Human pathology 2005;36(5):555-61.
2005: Postma C; Hermsen M A J A; Coffa J; Baak J P A; Mueller J D; Mueller E; Bethke B; Schouten J P; Stolte M; Meijer G A
Chromosomal instability in flat adenomas and carcinomas of the colon.
The Journal of pathology 2005;205(4):514-21.
2005: Hecht Jonathan L; Ince Tan A; Baak Jan P A; Baker Heather E; Ogden Maryann W; Mutter George L
Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(3):324-30.
2005: Hermsen Mario; Snijders Antoine; Guervós Marta Alonso; Taenzer Simone; Koerner Ulrike; Baak Jan; Pinkel Daniel; Albertson Donna; van Diest Paul; Meijer Gerrit; Schrock Evelin
Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas.
Oncogene 2005;24(9):1571-9.
2005: Baak J P A; Mutter G L
EIN and WHO94.
Journal of clinical pathology 2005;58(1):1-6.
2005: Baak Jan P A; Kruse Arnold-Jan; Janssen Emiel; van Diermen Bianca
Predictive testing of early CIN behaviour by molecular biomarkers.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2005;27(5-6):277-80.
2005: Baak Jan P A; Kruse Arnold-Jan
Use of biomarkers in the evaluation of CIN grade and progression of early CIN.
Methods in molecular medicine 2005;119():85-99.
2005: Baak J P A; Janssen E A M; Soreide K; Heikkilae R
Genomics and proteomics--the way forward.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16 Suppl 2():ii30-44.
2004: van Diest P J; van der Wall E; Baak J P A
Prognostic value of proliferation in invasive breast cancer: a review.
Journal of clinical pathology 2004;57(7):675-81.
2004: Kruse Amold-Jan; Gudlaugsson Einar; Helliesen Tove; Janssen Emiel A; van Diermen Bianca; Sandvik Silje; Baak Jan P
Evaluation of prospective, routine application of Ki-67 immunoquantitation in early CIN for assessment of short-term progression risk.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2004;26(3):134-40.
2004: Baak J P A; Janssen E
DNA ploidy analysis in histopathology. Morphometry and DNA cytometry reproducibility conditions and clinical applications.
Histopathology 2004;44(6):603-14.
2004: Kruse Arnold-Jan; Skaland Ivar; Janssen Emiel A; Buhr-Wildhagen Suzanne; Klos Jan; Arends Mark J; Baak Jan P A
Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2004;23(2):100-9.
2004: Kruse Arnold-Jan; Baak Jan P A; Janssen Emiel A; Kjellevold Kjell-Henning; Fiane Bent; Lovslett Kjell; Bergh Johan; Robboy Stanley
Ki67 predicts progression in early CIN: validation of a multivariate progression-risk model.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2004;26(1-2):13-20.
2004: Kruse Arnold-Jan; Buhr-Wildhagen Susanne; Janssen Emiel A; Baak Jan P A
The relationship between syntactic structure analysis features, histological grade and high-risk HPV DNA in cervical intraepithelial neoplasia.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2004;26(3):135-41.
2004: van Grieken Nicole C T; Meijer Gerrit A; Kale Ilse; Bloemena Elisabeth; Lindeman Jan; Offerhaus G Johan A; Meuwissen Stefan G M; Baak Jan P A; Kuipers Ernst J
Quantitative assessment of gastric antrum atrophy shows restitution to normal histology after Helicobacter pylori eradication.
Digestion 2004;69(1):27-33.
2003: Bos Reinhard; van Diest Paul J; van der Groep Petra; Greijer Astrid E; Hermsen Mario A J A; Heijnen Ingrid; Meijer Gerrit A; Baak Jan P A; Pinedo Herbert M; van der Wall Elsken; Shvarts Avi
Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha).
Oncogene 2003;22(55):8948-51.
2003: Janssen Emiel A M; Baak Jan P A; Guervós Marta Alonso; van Diest Paul J; Jiwa M; Hermsen Mario A J A
In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor.
The Journal of pathology 2003;201(4):555-61.
2003: Baak Jan P A; Snijders Wim; van Diermen Bianca; van Diest Paul J; Diepenhorst Fred W; Benraadt Jantine
Prospective multicenter validation confirms the prognostic superiority of the endometrial carcinoma prognostic index in international Federation of gynecology and obstetrics stage 1 and 2 endometrial carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(22):4214-21.
2003: Kruse Arnold-Jan; Baak Jan P A; Helliesen Tove; Kjellevold Kjell-Henning; Robboy Stanley J
Prognostic value and reproducibility of koilocytosis in cervical intraepithelial neoplasia.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2003;22(3):236-9.
2003: Baak Jan P A; Bol Marco G W; van Diermen Bianca; Janssen E A M; Buhr-Wildhagen Susanne B K; Mestad Oddvar; Øgreid Per; Kjellevold Kjell-Henning
DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality.
Urology 2003;61(6):1266-72.
2003: Bol M G W; Baak J P A; van Diermen B; Buhr-Wildhagen S; Janssen E A M; Kjellevold K H; Kruse A J; Mestad O; Øgreid P
Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomas: identification of subgroups with low and high stage progression risks.
Journal of clinical pathology 2003;56(6):447-52.
2003: Baak J P A; Path F R C; Hermsen M A J A; Meijer G; Schmidt J; Janssen E A M
Genomics and proteomics in cancer.
European journal of cancer (Oxford, England : 1990) 2003;39(9):1199-215.
2003: Ruivenkamp Claudia; Hermsen Mario; Postma Cindy; Klous Anita; Baak Jan; Meijer Gerrit; Demant Peter
LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21.
Oncogene 2003;22(22):3472-4.
2003: van Grieken N C T; Meijer G A; zur Hausen A; Meuwissen S G M; Baak J P A; Kuipers E J
Increased apoptosis in gastric mucosa adjacent to intestinal metaplasia.
Journal of clinical pathology 2003;56(5):358-61.
2003: Kruse Arnold-Jan; Baak Jan P A; Janssen Emiel A; Bol Marco G W; Kjellevold Kjell-Henning; Fianne Bernt; Lovslett Kjell; Bergh Johan
Low- and high-risk CIN 1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables.
The Journal of pathology 2003;199(4):462-70.
2003: Bol Marco G; Baak Jan P; Buhr-Wildhagen Susanne; Kruse Arnold-Jan; Kjellevold Kjell H; Janssen Emiel A; Mestad Oddvar; Øgreid Per
Reproducibility and prognostic variability of grade and lamina propria invasion in stages Ta, T1 urothelial carcinoma of the bladder.
The Journal of urology 2003;169(4):1291-4.
2003: Weiss Marjan M; Kuipers Ernst J; Hermsen Mario A J A; van Grieken Nicole C T; Offerhaus Johan; Baak Jan P A; Meuwissen Stefan G M; Meijer Gerrit A
Barrett's adenocarcinomas resemble adenocarcinomas of the gastric cardia in terms of chromosomal copy number changes, but relate to squamous cell carcinomas of the distal oesophagus with respect to the presence of high-level amplifications.
The Journal of pathology 2003;199(2):157-65.
2003: van der Wal J E; Hermsen M A J A; Gille H J P; Schouten-Van Meeteren N Y N; Moll A C; Imhof S M; Meijer G A; Baak J P A; van der Valk P
Comparative genomic hybridisation divides retinoblastomas into a high and a low level chromosomal instability group.
Journal of clinical pathology 2003;56(1):26-30.
2003: Bol Marco G W; Baak Jan P A; Diermen Bianca; Janssen E A M; Buhr-Wildhagen Susanne B K; Kjellevold Kjell-Henning
Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2003;25(3):147-53.
2003: Polkowski Wojciech; van Lanschot J Jan B; van Sandick Johanna W; Baak Jan P A
The role of quantitative pathology in clinical decision making for Barrett's oesophagus.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2003;25(3):123-7.
2002: Bol Marco G W; Baak Jan P A; Rep Simon; Marx Willem L; Kruse Arnold Jan; Bos Siebe D; Kisman Otto; Voorhorst Feja J
Prognostic value of proliferative activity and nuclear morphometry for progression in TaT1 urothelial cell carcinomas of the urinary bladder.
Urology 2002;60(6):1124-30.
2002: Baak J P A; ten Kate F J W; Offerhaus G J A; van Lanschot J J; Meijer G A
Routine morphometrical analysis can improve reproducibility of dysplasia grade in Barrett's oesophagus surveillance biopsies.
Journal of clinical pathology 2002;55(12):910-6.
2002: Kruse Arnold-Jan; Baak Jan P A; Helliesen Tove; Kjellevold Kjell H; Bol Marco G W; Janssen Emiel A M
Evaluation of MIB-1-positive cell clusters as a diagnostic marker for cervical intraepithelial neoplasia.
The American journal of surgical pathology 2002;26(11):1501-7.
2002: Baak Jan P A
The framework of pathology: good laboratory practice by quantitative and molecular methods.
The Journal of pathology 2002;198(3):277-83.
2002: Hermsen Mario; Postma Cindy; Baak Jan; Weiss Marjan; Rapallo Anna; Sciutto Andrea; Roemen Guido; Arends Jan-Willem; Williams Richard; Giaretti Walter; De Goeij Anton; Meijer Gerrit
Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability.
Gastroenterology 2002;123(4):1109-19.
2002: Beliën Jeroen A M; van Ginkel Hielke A H M; Tekola Paulos; Ploeger Lennert S; Poulin Neal M; Baak Jan P A; van Diest Paul J
Confocal DNA cytometry: a contour-based segmentation algorithm for automated three-dimensional image segmentation.
Cytometry 2002;49(1):12-21.
2002: Louwman W J; van Diest P J; van Beek M W P M; Schapers R F M; Nolthenius-Puylaert M B C J E Tutein; Baak J P A; Coebergh J W W
Trends in breast cancer aggressiveness before the introduction of mass screening in southeastern Netherlands 1975-1989.
Breast cancer research and treatment 2002;73(3):199-206.
2002: Bol Marco G W; Baak Jan P A; Janssen Emiel A M; Breeuwsma Nelly G; de Bruin Peter C
Further testing of morphometric grading in T(A,1) urothelial carcinomas of the urinary bladder and the additional value of p53 immunoquantitation.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2002;24(2):114-20.
2002: Michiels Erna M C; Weiss Marjan M; Hoovers Jan M N; Baak Jan P A; Voûte P A; Baas Frank; Hermsen Mario A J A
Genetic alterations in childhood medulloblastoma analyzed by comparative genomic hybridization.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2002;24(3):205-10.
2002: Brinkhuis Mariël; Izquierdo Miguel A; Baak Jan P A; van Diest Paul J; Kenemans Peter; Scheffer George L; Scheper Rik J
Expression of multidrug resistance-associated markers, their relation to quantitative pathologic tumour characteristics and prognosis in advanced ovarian cancer.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2002;24(1):17-23.
2001: Kruse A J; Baak J P; de Bruin P C; van de Goot F R; Kurten N
Relationship between the presence of oncogenic HPV DNA assessed by polymerase chain reaction and Ki-67 immunoquantitative features in cervical intraepithelial neoplasia.
The Journal of pathology 2001;195(5):557-62.
2001: Bol M G; Baak J P; de Bruin P C; Rep S; Marx W; Bos S; Kisman O
Improved objectivity of grading of T(A,1) transitional cell carcinomas of the urinary bladder by quantitative nuclear and proliferation related features.
Journal of clinical pathology 2001;54(11):854-9.
2001: Mutter G L; Baak J P; Fitzgerald J T; Gray R; Neuberg D; Kust G A; Gentleman R; Gullans S R; Wei L J; Wilcox M
Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation.
Gynecologic oncology 2001;83(2):177-85.
2001: van Grieken N C; Meijer G A; Weiss M M; Bloemena E; Lindeman J; Baak J P; Meuwissen S G; Kuipers E J
Quantitative assessment of gastric corpus atrophy in subjects using omeprazole: a randomized follow-up study.
The American journal of gastroenterology 2001;96(10):2882-6.
2001: Zweemer R P; Ryan A; Snijders A M; Hermsen M A; Meijer G A; Beller U; Menko F H; Jacobs I J; Baak J P; Verheijen R H; Kenemans P; van Diest P J
Comparative genomic hybridization of microdissected familial ovarian carcinoma: two deleted regions on chromosome 15q not previously identified in sporadic ovarian carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1363-70.
2001: zur Hausen A; van Grieken N C; Meijer G A; Hermsen M A; Bloemena E; Meuwissen S G; Baak J P; Meijer C J; Kuipers E J; van den Brule A J
Distinct chromosomal aberrations in Epstein-Barr virus-carrying gastric carcinomas tested by comparative genomic hybridization.
Gastroenterology 2001;121(3):612-8.
2001: Mommers E C; Page D L; Dupont W D; Schuyler P; Leonhart A M; Baak J P; Meijer C J; van Diest P J
Prognostic value of morphometry in patients with normal breast tissue or usual ductal hyperplasia of the breast.
International journal of cancer. Journal international du cancer 2001;95(5):282-5.
2001: Mommers E C; Leonhart A M; Falix F; Michalides R; Meijer C J; Baak J P; Diest P J
Similarity in expression of cell cycle proteins between in situ and invasive ductal breast lesions of same differentiation grade.
The Journal of pathology 2001;194(3):327-33.
2001: Baak J P; Ørbo A; van Diest P J; Jiwa M; de Bruin P; Broeckaert M; Snijders W; Boodt P J; Fons G; Burger C; Verheijen R H; Houben P W; The H S; Kenemans P
Prospective multicenter evaluation of the morphometric D-score for prediction of the outcome of endometrial hyperplasias.
The American journal of surgical pathology 2001;25(7):930-5.
2001: Hermsen M; Guervós M A; Meijer G; Baak J; van Diest P; Marcos C A; Sampedro A
New chromosomal regions with high-level amplifications in squamous cell carcinomas of the larynx and pharynx, identified by comparative genomic hybridization.
The Journal of pathology 2001;194(2):177-82.
2001: Mutter G L; Ince T A; Baak J P; Kust G A; Zhou X P; Eng C
Molecular identification of latent precancers in histologically normal endometrium.
Cancer research 2001;61(11):4311-4.
2001: de Jong J S; van Diest P J; van der Valk P; Baak J P
Expression of growth factors, growth factor receptors and apoptosis related proteins in invasive breast cancer: relation to apoptotic rate.
Breast cancer research and treatment 2001;66(3):201-8.
2001: van Bodegraven A A; Schoorl M; Baak J P; Linskens R K; Bartels P C; Tuynman H A
Hemostatic imbalance in active and quiescent ulcerative colitis.
The American journal of gastroenterology 2001;96(2):487-93.
2001: van Grieken N C; Weiss M M; Meijer G A; Bloemena E; Lindeman J; Offerhaus G J; Meuwissen S G; Baak J P; Kuipers E J
Rapid quantitative assessment of gastric corpus atrophy in tissue sections.
Journal of clinical pathology 2001;54(1):63-9.
2001: Kruse A J; Baak J P; de Bruin P C; Jiwa M; Snijders W P; Boodt P J; Fons G; Houben P W; The H S
Ki-67 immunoquantitation in cervical intraepithelial neoplasia (CIN): a sensitive marker for grading.
The Journal of pathology 2001;193(1):48-54.
2001: Mommers E C; Poulin N; Sangulin J; Meijer C J; Baak J P; van Diest P J
Nuclear cytometric changes in breast carcinogenesis.
The Journal of pathology 2001;193(1):33-9.
2001: Hermsen M A; Weiss M M; Meijer G A; Baak J P
Detection of chromosomal abnormalities by comparative genomic hybridization.
Methods in molecular biology (Clifton, N.J.) 2001;175():47-55.
2000: van Grieken N C; Weiss M M; Meijer G A; Hermsen M A; Scholte G H; Lindeman J; Craanen M E; Bloemena E; Meuwissen S G; Baak J P; Kuipers E J
Helicobacter pylori-related and -non-related gastric cancers do not differ with respect to chromosomal aberrations.
The Journal of pathology 2000;192(3):301-6.
2000: Orbo A; Baak J P; Kleivan I; Lysne S; Prytz P S; Broeckaert M A; Slappendel A; Tichelaar H J
Computerised morphometrical analysis in endometrial hyperplasia for the prediction of cancer development. A long-term retrospective study from northern Norway.
Journal of clinical pathology 2000;53(9):697-703.
2000: Mutter G L; Lin M C; Fitzgerald J T; Kum J B; Baak J P; Lees J A; Weng L P; Eng C
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers.
Journal of the National Cancer Institute 2000;92(11):924-30.
2000: de Jong J S; van Diest P J; Baak J P
Hot spot microvessel density and the mitotic activity index are strong additional prognostic indicators in invasive breast cancer.
Histopathology 2000;36(4):306-12.
2000: Mutter G L; Baak J P; Crum C P; Richart R M; Ferenczy A; Faquin W C
Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry.
The Journal of pathology 2000;190(4):462-9.
2000: van Sandick J W; Baak J P; van Lanschot J J; Polkowski W; ten Kate F J; Obertop H; Offerhaus G J
Computerized quantitative pathology for the grading of dysplasia in surveillance biopsies of Barrett's oesophagus.
The Journal of pathology 2000;190(2):177-83.
2000: de Jong J S; van Diest P J; Baak J P
Number of apoptotic cells as a prognostic marker in invasive breast cancer.
British journal of cancer 2000;82(2):368-73.
2000: Baak J P; van Diest P J; Meijer G A
Experience with a dynamic inexpensive video-conferencing system for frozen section telepathology.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2000;21(3-4):169-75.
2000: Giaretti W; Rapallo A; Sciutto A; Macciocu B; Geido E; Hermsen M A; Postma C; Baak J P; Williams R A; Meijer G A
Intratumor heterogeneity of k-ras and p53 mutations among human colorectal adenomas containing early cancer.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2000;21(2):49-57.
2000: Mommers E C; Poulin N; Meijer C J; Baak J P; van Diest P J
Malignancy-associated changes in breast tissue detected by image cytometry.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2000;20(4):187-95.
1999: Mommers E C; van Diest P J; Leonhart A M; Meijer C J; Baak J P
Balance of cell proliferation and apoptosis in breast carcinogenesis.
Breast cancer research and treatment 1999;58(2):163-9.
1999: Torenbeek R; Hermsen M A; Meijer G A; Baak J P; Meijer C J
Analysis by comparative genomic hybridization of epithelial and spindle cell components in sarcomatoid carcinoma and carcinosarcoma: histogenetic aspects.
The Journal of pathology 1999;189(3):338-43.
1999: Beliën J A; van Diest P J; Baak J P
Relationships between vascularization and proliferation in invasive breast cancer.
The Journal of pathology 1999;189(3):309-18.
1999: Weiss M M; Hermsen M A; Meijer G A; van Grieken N C; Baak J P; Kuipers E J; van Diest P J
Comparative genomic hybridisation.
Molecular pathology : MP 1999;52(5):243-51.
1999: Mommers E C; Leonhart A M; von Mensdorff-Pouilly S; Schol D J; Hilgers J; Meijer C J; Baak J P; van Diest P J
Aberrant expression of MUC1 mucin in ductal hyperplasia and ductal carcinoma In situ of the breast.
International journal of cancer. Journal international du cancer 1999;84(5):466-9.
1999: Meijer G A; Schroeijers A B; Flens M J; Meuwissen S G; van der Valk P; Baak J P; Scheper R J
Increased expression of multidrug resistance related proteins Pgp, MRP1, and LRP/MVP occurs early in colorectal carcinogenesis.
Journal of clinical pathology 1999;52(6):450-4.
1999: de Jong J S; van Diest P J; Michalides R J; Baak J P
Concerted overexpression of the genes encoding p21 and cyclin D1 is associated with growth inhibition and differentiation in various carcinomas.
Molecular pathology : MP 1999;52(2):78-83.
1999: Beliën J A; Somi S; de Jong J S; van Diest P J; Baak J P
Fully automated microvessel counting and hot spot selection by image processing of whole tumour sections in invasive breast cancer.
Journal of clinical pathology 1999;52(3):184-92.
1998: Hermsen M A; Baak J P; Meijer G A; Weiss J M; Walboomers J W; Snijders P J; van Diest P J
Genetic analysis of 53 lymph node-negative breast carcinomas by CGH and relation to clinical, pathological, morphometric, and DNA cytometric prognostic factors.
The Journal of pathology 1998;186(4):356-62.
1998: Meijer G A; Hermsen M A; Baak J P; van Diest P J; Meuwissen S G; Beliën J A; Hoovers J M; Joenje H; Snijders P J; Walboomers J M
Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation.
Journal of clinical pathology 1998;51(12):901-9.
1998: Mommers E C; van Diest P J; Leonhart A M; Meijer C J; Baak J P
Expression of proliferation and apoptosis-related proteins in usual ductal hyperplasia of the breast.
Human pathology 1998;29(12):1539-45.
1998: van Diest P J; Brugal G; Baak J P
Proliferation markers in tumours: interpretation and clinical value.
Journal of clinical pathology 1998;51(10):716-24.
1998: Steenbergen R D; Hermsen M A; Walboomers J M; Meijer G A; Baak J P; Meijer C J; Snijders P J
Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.
International journal of cancer. Journal international du cancer 1998;76(3):412-7.
1998: de Jong J S; van Diest P J; Michalides R J; van der Valk P; Meijer C J; Baak J P
Correlation of cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer.
Molecular pathology : MP 1998;51(1):30-4.
1998: Polkowski W; Baak J P; van Lanschot J J; Meijer G A; Schuurmans L T; Ten Kate F J; Obertop H; Offerhaus G J
Clinical decision making in Barrett's oesophagus can be supported by computerized immunoquantitation and morphometry of features associated with proliferation and differentiation.
The Journal of pathology 1998;184(2):161-8.
1998: Brugghe J; Baak J P; Meijer G A; van Diest P J; Brinkhuis M
Rapid and reliable assessment of volume percentage of epithelium in borderline and invasive ovarian tumors.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1998;20(1):14-20.
1998: Meijer G A; Baak J P; Talbot I C; Atkin W S; Meuwissen S G
Predicting the risk of metachronous colorectal cancer in patients with rectosigmoid adenoma using quantitative pathological features. A case-control study.
The Journal of pathology 1998;184(1):63-70.
1998: de Jong J S; van Diest P J; van der Valk P; Baak J P
Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis.
The Journal of pathology 1998;184(1):53-7.
1998: de Jong J S; van Diest P J; van der Valk P; Baak J P
Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops.
The Journal of pathology 1998;184(1):44-52.
1998: Brugghe J; Baak J P; Wiltshaw E; Brinkhuis M; Meijer G A; Fisher C
Quantitative prognostic features in FIGO I ovarian cancer patients without postoperative treatment.
Gynecologic oncology 1998;68(1):47-53.
1997: Hermsen M A; Joenje H; Arwert F; Braakhuis B J; Baak J P; Westerveld A; Slater R
Assessment of chromosomal gains and losses in oral squamous cell carcinoma by comparative genomic hybridisation.
Oral oncology 1997;33(6):414-8.
1997: Bergers E; Baak J P; van Diest P J; Willig A J; Los J; Peterse J L; Ruitenberg H M; Schapers R F; Somsen J G; van Beek M W; Bellot S M; Fijnheer J; van Gorp L H
Prognostic value of DNA ploidy using flow cytometry in 1301 breast cancer patients: results of the prospective Multicenter Morphometric Mammary Carcinoma Project.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1997;10(8):762-8.
1997: Bergers E; van Diest P J; Baak J P
Reliable DNA histogram interpretation. Number of nuclei requiring measurement with flow cytometry.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(4):277-84.
1997: Bergers E; Baak J P; van Diest P J; van Gorp L H; Kwee W S; Los J; Peterse H L; Ruitenberg H M; Schapers R F; Somsen J G; van Beek M W; Bellot S M; Fijnheer J
Prognostic implications of different cell cycle analysis models of flow cytometric DNA histograms of 1,301 breast cancer patients: results from the Multicenter Morphometric Mammary Carcinoma Project (MMMCP).
International journal of cancer. Journal international du cancer 1997;74(3):260-9.
1997: Polkowski W; Meijer G A; Baak J P; ten Kate F J; Obertop H; Offerhaus G J; van Lanschot J J
Reproducibility of p53 and Ki-67 immunoquantitation in Barrett's esophagus.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(3):246-54.
1997: Brinkhuis M; Meijer G A; van Diest P J; Schuurmans L T; Baak J P
Minimum spanning tree analysis in advanced ovarian carcinoma. An investigation of sampling methods, reproducibility and correlation with histologic grade.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(3):194-201.
1997: Brinkhuis M; Scheepstra C; Buist M R; van Diest P J; Baak J P
Intratumor heterogeneity of morphometric and stereologic variables in primary ovarian tumors and their omental metastatic deposits.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(3):185-93.
1997: Beliën J A; Baak J P; van Diest P J; van Ginkel A H
Counting mitoses by image processing in Feulgen stained breast cancer sections: the influence of resolution.
Cytometry 1997;28(2):135-40.
1997: Meijer G A; Beliën J A; van Diest P J; Baak J P
Origins of ... image analysis in clinical pathology.
Journal of clinical pathology 1997;50(5):365-70.
1997: Bergers E; van Diest P J; Baak J P
Comparison of five cell cycle analysis models applied to 1414 flow cytometric DNA histograms of fresh frozen breast cancer.
Cytometry 1997;30(1):54-60.
1997: van Diest P J; Michalides R J; Jannink L; van der Valk P; Peterse H L; de Jong J S; Meijer C J; Baak J P
Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value.
The American journal of pathology 1997;150(2):705-11.
1997: Bergers E; Jannink I; van Diest P I; Cuesta M A; Meyer S; van Mourik J C; Baak J P
The influence of fixation delay on mitotic activity and flow cytometric cell cycle variables.
Human pathology 1997;28(1):95-100.
1996: Jannink I; Risberg B; Van Diest P J; Baak J P
Heterogeneity of mitotic activity in breast cancer.
Histopathology 1996;29(5):421-8.
1996: Bergers E; van Diest P J; Baak J P
Tumour heterogeneity of DNA cell cycle variables in breast cancer measured by flow cytometry.
Journal of clinical pathology 1996;49(11):931-7.
1996: Tekola P; Baak J P; van Ginkel H A; Belien J A; van Diest P J; Broeckaert M A; Schuurmans L T
Three-dimensional confocal laser scanning DNA ploidy cytometry in thick histological sections.
The Journal of pathology 1996;180(2):214-22.
1996: Meijer G A; Baak J P; van Diest P J; van Hattum A H; van der Linden H C; Koevoets J J
Text processing by digital voice recognition.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1996;18(4):261-6.
1996: Meijer G A; van Diest P J; Baak J P; Brinkhuis M; Beentjes M
Influence of boundary effects on minimum spanning tree features. A computer simulation.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1996;18(3):225-32.
1996: Bergers E; Montironi R; van Diest P J; Prete E; Baak J P
Interlaboratory reproducibility of semiautomated cell cycle analysis of flow cytometry DNA-histograms obtained from fresh material of 1,295 breast cancer cases.
Human pathology 1996;27(6):553-60.
1996: Bergers E; van Diest P J; Baak J P
Cell cycle analysis of 932 flow cytometric DNA histograms of fresh frozen breast carcinoma material. Correlations between flow cytometric, clinical, and pathologic variables. MMMCP Collaborative Group. Multicenter Morphometric Mammary Carcinoma Project Collaborative Group.
Cancer 1996;77(11):2258-66.
1996: Boerrigter P J; van de Weijer P H; Baak J P; Fox H; Haspels A A; Kenemans P
Endometrial response in estrogen replacement therapy quarterly combined with a progestogen.
Maturitas 1996;24(1-2):63-71.
1996: Oudejans J J; Jiwa N M; Kummer J A; Horstman A; Vos W; Baak J P; Kluin P M; van der Valk P; Walboomers J M; Meijer C J
Analysis of major histocompatibility complex class I expression on Reed-Sternberg cells in relation to the cytotoxic T-cell response in Epstein-Barr virus-positive and -negative Hodgkin's disease.
Blood 1996;87(9):3844-51.
1996: Hermsen M A; Meijer G A; Baak J P; Joenje H; Walboomers J J
Comparative genomic hybridization: a new tool in cancer pathology.
Human pathology 1996;27(4):342-9.
1996: Brinkhuis M; Baak J P; Meijer G A; van Diest P J; Mogensen O; Bichel P; Neijt J P
Value of quantitative pathological variables as prognostic factors in advanced ovarian carcinoma.
Journal of clinical pathology 1996;49(2):142-8.
1995: Brinkhuis M; Meijer G A; Baak J P
An evaluation of prognostic factors in advanced ovarian cancer.
European journal of obstetrics, gynecology, and reproductive biology 1995;63(2):115-24.
1995: Meijer G A; Meuwissen S G; Baak J P
Classification of colorectal adenomas with quantitative pathology. Evaluation of morphometry, stereology, mitotic counts and syntactic structure analysis.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1995;9(4):311-23.
1995: de Jong J S; van Diest P J; Baak J P
Heterogeneity and reproducibility of microvessel counts in breast cancer.
Laboratory investigation; a journal of technical methods and pathology 1995;73(6):922-6.
1995: Beliën J A; Copper M P; Braakhuis B J; Snow G B; Baak J P
Standardization of counting micronuclei: definition of a protocol to measure genotoxic damage in human exfoliated cells.
Carcinogenesis 1995;16(10):2395-400.
1995: Jannink I; van Diest P J; Baak J P
Comparison of the prognostic value of four methods to assess mitotic activity in 186 invasive breast cancer patients: classical and random mitotic activity assessments with correction for volume percentage of epithelium.
Human pathology 1995;26(10):1086-92.
1995: Linn S C; Giaccone G; van Diest P J; Blokhuis W M; van der Valk P; van Kalken C K; Kuiper C M; Pinedo H M; Baak J P
Prognostic relevance of P-glycoprotein expression in breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6(7):679-85.
1995: Brinkhuis M; Meijer G A; Beliën J A; van Diest P J; Baak J P
Volume-weighted mean nuclear volume and nuclear area in advanced ovarian carcinoma. An investigation of sampling methods, sample size and reproducibility.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1995;17(4):284-90.
1995: Meijer G A; Baak J P
Quantification of proliferative activity in colorectal adenomas by mitotic counts: relationship to degree of dysplasia and histological type.
Journal of clinical pathology 1995;48(7):620-5.
1995: van Diest P J; Kayser K; Meijer G A; Baak J P
Syntactic structure analysis.
Pathologica 1995;87(3):255-62.
1995: Polkowski W; van Lanschot J J; Ten Kate F J; Baak J P; Tytgat G N; Obertop H; Voorn W J; Offerhaus G J
The value of p53 and Ki67 as markers for tumour progression in the Barrett's dysplasia-carcinoma sequence.
Surgical oncology 1995;4(3):163-71.
1995: Buist M R; Kenemans P; Molthoff C F; Roos J C; Den Hollander W; Brinkhuis M; Baak J P
Tumor uptake of intravenously administered radiolabeled antibodies in ovarian carcinoma patients in relation to antigen expression and other tumor characteristics.
International journal of cancer. Journal international du cancer 1995;64(2):92-8.
1995: Makkink-Nombrado S V; Baak J P; Schuurmans L; Theeuwes J W; van der Aa T
Quantitative immunohistochemistry using the CAS 200/486 image analysis system in invasive breast carcinoma: a reproducibility study.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1995;8(3):227-45.
1995: van Diest P J; Zevering J P; Zevering L C; Baak J P
Prognostic value of microvessel quantitation in cisplatin treated FIGO 3 and 4 ovarian cancer patients.
Pathology, research and practice 1995;191(1):25-30.
1995: Schuurhuis G J; Broxterman H J; Ossenkoppele G J; Baak J P; Eekman C A; Kuiper C M; Feller N; van Heijningen T H; Klumper E; Pieters R
Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(1):81-93.
1995: Bergers E; van Diest P J; Baak J P
Reproducibility of semi-automated cell cycle analysis of flow cytometric DNA-histograms of fresh breast cancer material.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1995;8(1):1-13.
1995: Baak J P
The role of computerized morphometric and cytometric feature analysis in endometrial hyperplasia and cancer prognosis.
Journal of cellular biochemistry. Supplement 1995;23():137-46.
1995: Brinkhuis M; Wijnaendts L C; van der Linden J C; van Unnik A J; Voûte P A; Baak J P; Meijer C J
Peripheral primitive neuroectodermal tumour and extra-osseous Ewing's sarcoma; a histological, immunohistochemical and DNA flow cytometric study.
Virchows Archiv : an international journal of pathology 1995;425(6):611-6.
1995: Jannink I; Bennen J N; Blaauw J; van Diest P J; Baak J P
At convenience and systematic random sampling: effects on the prognostic value of nuclear area assessments in breast cancer patients.
Breast cancer research and treatment 1995;36(1):55-60.
1994: Tekola P; Baak J P; Beliën J A; Brugghe J
Highly sensitive, specific, and stable new fluorescent DNA stains for confocal laser microscopy and image processing of normal paraffin sections.
Cytometry 1994;17(3):191-5.
1994: Van Diest P J; Beliën J A; Zanstra P E; Wilhelm W W; Baak J P
Integrated decision support system/image archive for histological typing of breast cancer using a relation oriented inference system.
Histopathology 1994;25(3):253-9.
1994: Meijer G A; Fleege J C; Baak J P
Stereological assessment of architectural changes in dysplastic epithelium of colorectal adenomas.
Pathology, research and practice 1994;190(4):333-41.
1994: Zhu Q; Tekola P; Baak J P; Beliën J A
Measurement by confocal laser scanning microscopy of the volume of epidermal nuclei in thick skin sections.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1994;16(2):145-52.
1994: Buist M R; Golding R P; Burger C W; Vermorken J B; Kenemans P; Schutter E M; Baak J P; Heitbrink M A; Falke T H
Comparative evaluation of diagnostic methods in ovarian carcinoma with emphasis on CT and MRI.
Gynecologic oncology 1994;52(2):191-8.
1994: Baak J P; Ladekarl M; Sørensen F B
Reproducibility of mean nuclear volume and correlation with mean nuclear area in breast cancer: an investigation of various sampling schemes.
Human pathology 1994;25(1):80-5.
1994: Tekola P; Zhu Q; Baak J P
Confocal laser microscopy and image processing for three-dimensional microscopy: technical principles and an application to breast cancer.
Human pathology 1994;25(1):12-21.
1994: van Diest P J; Baak J P
Biomarkers of breast hyperplasias and in situ carcinomas: an overview.
Journal of cellular biochemistry. Supplement 1994;19():99-104.
1993: Buist M R; Kenemans P; den Hollander W; Vermorken J B; Molthoff C J; Burger C W; Helmerhorst T J; Baak J P; Roos J C
Kinetics and tissue distribution of the radiolabeled chimeric monoclonal antibody MOv18 IgG and F(ab')2 fragments in ovarian carcinoma patients.
Cancer research 1993;53(22):5413-8.
1993: Schuurhuis G J; van Heijningen T H; Cervantes A; Pinedo H M; de Lange J H; Keizer H G; Broxterman H J; Baak J P; Lankelma J
Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells.
British journal of cancer 1993;68(5):898-908.
1993: Fleege J C; van Diest P J; Baak J P
Systematic random sampling for selective interactive nuclear morphometry in breast cancer sections. Refinement and multiobserver evaluation.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1993;15(4):281-9.
1993: ten Kate T K; Beliën J A; Smeulders A W; Baak J P
Method for counting mitoses by image processing in Feulgen stained breast cancer sections.
Cytometry 1993;14(3):241-50.
1993: Baak J P; Makkink-Nombrado S; Tekola P; Bergers E; Beliën J A; van Ginkel A H
Quantitative microscopical and confocal laser scanning microscopy for intermediate endpoint biomarkers in breast cancer: potential and reproducibility.
Journal of cellular biochemistry. Supplement 1993;17G():98-106.
1993: Baak J P; van Diest P J; Benraadt T; Matze-Cok E; Brugghe J; Schuurmans L T; Littooy J J
The Multi-Center Morphometric Mammary Carcinoma Project (MMMCP) in The Netherlands: value of morphometrically assessed proliferation and differentiation.
Journal of cellular biochemistry. Supplement 1993;17G():220-5.
1992: Meijer G A; van Diest P J; Fleege J C; Baak J P
Syntactic structure analysis of the arrangement of nuclei in dysplastic epithelium of colorectal adenomatous polyps.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1992;14(6):491-8.
1992: Baak J P; Wisse-Brekelmans E C; Fleege J C; van der Putten H W; Bezemer P D
Assessment of the risk on endometrial cancer in hyperplasia, by means of morphological and morphometrical features.
Pathology, research and practice 1992;188(7):856-9.
1992: van Diest P J; Fleege J C; Matze-Cok E; Baak J P
Intra-patient variation between breast cancer axillary lymph node metastases using quantifiable features.
Histopathology 1992;21(3):257-62.
1992: Baak J P; Wisse-Brekelmans E C; Kurver P H; van Gorp L H; Voorhorst F J; Miettinen O S
Regional differences in breast cancer survival are correlated with differences in differentiation and rate of proliferation.
Human pathology 1992;23(9):989-92.
1992: van Diest P J; Fleege J C; Baak J P
Syntactic structure analysis in invasive breast cancer: analysis of reproducibility, biologic background, and prognostic value.
Human pathology 1992;23(8):876-83.
1992: van Diest P J; Baak J P; Matze-Cok P; Wisse-Brekelmans E C; van Galen C M; Kurver P H; Bellot S M; Fijnheer J; van Gorp L H; Kwee W S
Reproducibility of mitosis counting in 2,469 breast cancer specimens: results from the Multicenter Morphometric Mammary Carcinoma Project.
Human pathology 1992;23(6):603-7.
1992: Thunnissen F B; Diegenbach P C; van Hattum A H; Tolboom J; van der Sluis D M; Schaafsma W; Houthoff H J; Baak J P
Further evaluation of quantitative nuclear image features for classification of lung carcinomas.
Pathology, research and practice 1992;188(4-5):531-5.
1992: van Diest P J; Belien J A; Baak J P
An expert system for histological typing and grading of invasive breast cancer. First set up.
Pathology, research and practice 1992;188(4-5):405-9.
1992: van Diest P J; Baak J P; Matze-Cok P; Bacus S S
Prediction of response to adjuvant chemotherapy in premenopausal lymph node positive breast cancer patients with morphometry, DNA flow cytometry and HER-2/neu oncoprotein expression. Preliminary results.
Pathology, research and practice 1992;188(3):344-9.
1992: Fleege J C; van Diest P J; Baak J P
Quality control methods for data entry in pathology using a computerized data management system based on an extended data dictionary.
Human pathology 1992;23(2):91-7.
1992: Meijer G A; Baak J P
Cytonuclear morphometry in the assessment of dysplasia in colorectal adenomatous polyps. A pilot study.
Pathology, research and practice 1992;188(1-2):148-56.
1992: de Lange J H; Schipper N W; Schuurhuis G J; ten Kate T K; van Heijningen T H; Pinedo H M; Lankelma J; Baak J P
Quantification by laser scan microscopy of intracellular doxorubicin distribution.
Cytometry 1992;13(6):571-6.
1991: Schipper N W; Baak J P; Smeulders A W
Automated selection of the most epithelium-rich areas in gynecologic tumor sections.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1991;13(6):395-402.
1991: van den Brule A J; Cromme F V; Snijders P J; Smit L; Oudejans C B; Baak J P; Meijer C J; Walboomers J M
Nonradioactive RNA in situ hybridization detection of human papillomavirus 16-E7 transcripts in squamous cell carcinomas of the uterine cervix using confocal laser scan microscopy.
The American journal of pathology 1991;139(5):1037-45.
1991: Schuurhuis G J; Broxterman H J; de Lange J H; Pinedo H M; van Heijningen T H; Kuiper C M; Scheffer G L; Scheper R J; van Kalken C K; Baak J P
Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein.
British journal of cancer 1991;64(5):857-61.
1991: van Diest P J; Baak J P; Chin D; Theeuwes J W; Bacus S S
Quantitation of HER-2/neu oncoprotein overexpression in invasive breast cancer by image analysis: a study comparing fresh and paraffin-embedded material.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1991;3(4):195-202.
1991: van Diest P J; Matze-Cok E; Baak J P
Prognostic value of proliferative activity in lymph node metastases of patients with breast cancer.
Journal of clinical pathology 1991;44(5):416-8.
1991: Uyterlinde A M; Baak J P; Schipper N W; Peterse H J; Meijer J W; Vooys P G; Matze E
Prognostic value of morphometry and DNA flow-cytometry features of invasive breast cancers detected by population screening: comparison with control group of hospital patients.
International journal of cancer. Journal international du cancer 1991;48(2):173-81.
1991: Uyterlinde A M; Smeulders A W; Baak J P
DNA measurement errors with a scanning microdensitometer in cytologic and histologic samples of breast cancers.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1991;13(2):115-22.
1991: van Diest P J; Baak J P
The morphometric prognostic index is the strongest prognosticator in premenopausal lymph node-negative and lymph node-positive breast cancer patients.
Human pathology 1991;22(4):326-30.
1991: van Ingen G; Schoemaker J; Baak J P
A testosterone-producing tumour in the mesovarium.
Pathology, research and practice 1991;187(2-3):362-70; discussion 370-2.
1991: Slotman B J; Baak J P; Rao B R
Correlation between nuclear DNA content and steroid receptor status in ovarian cancer.
European journal of obstetrics, gynecology, and reproductive biology 1991;38(3):221-7.
1991: Baak J P; Chin D; van Diest P J; Ortiz R; Matze-Cok P; Bacus S S
Comparative long-term prognostic value of quantitative HER-2/neu protein expression, DNA ploidy, and morphometric and clinical features in paraffin-embedded invasive breast cancer.
Laboratory investigation; a journal of technical methods and pathology 1991;64(2):215-23.
1990: Schipper N W; Smeulders A W; Baak J P
Automated estimation of epithelial volume in breast cancer sections. A comparison with the image processing steps applied to gynecologic tumors.
Pathology, research and practice 1990;186(6):737-44.
1990: Fleege J C; van Diest P J; Baak J P
Computer assisted efficiency testing of different sampling methods for selective nuclear graphic tablet morphometry.
Laboratory investigation; a journal of technical methods and pathology 1990;63(2):270-5.
1990: Blomjous C E; Vos W; Schipper N W; Uyterlinde A M; Baak J P; de Voogt H J; Meijer C J
The prognostic significance of selective nuclear morphometry in urinary bladder carcinoma.
Human pathology 1990;21(4):409-13.
1990: van Diest P J; Mouriquand J; Schipper N W; Baak J P
Prognostic value of nucleolar morphometric variables in cytological breast cancer specimens.
Journal of clinical pathology 1990;43(2):157-9.
1990: Uyterlinde A M; Baak J P; Schipper N W; Peterse H; Matze E; Meijer C J
Further evaluation of the prognostic value of morphometric and flow cytometric parameters in breast-cancer patients with long follow-up.
International journal of cancer. Journal international du cancer 1990;45(1):1-7.
1989: Jansen W; van Ginneken A M; Baak J P; Smeulders A W
Construction of the diagnostic encyclopedia workstation. Computerizing pathology for the pathologist.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(6):447-50.
1989: Blomjous C E; Smeulders A W; Baak J P; Vos W; van Galen C M; Meijer C J
A comparative study in morphometric grading of transitional cell carcinoma of the urinary bladder.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(6):426-32.
1989: Schuurhuis G J; Broxterman H J; Cervantes A; van Heijningen T H; de Lange J H; Baak J P; Pinedo H M; Lankelma J
Quantitative determination of factors contributing to doxorubicin resistance in multidrug-resistant cells.
Journal of the National Cancer Institute 1989;81(24):1887-92.
1989: Schipper N W; Smeulders A W; de Lange J H; Baak J P
Quantification of epithelial area by image processing applied to endometrial carcinomas: a comparison with ovarian tumors.
Human pathology 1989;20(11):1125-32.
1989: Baak J P; van Diest P J; Ariens A T; van Beek M W; Bellot S M; Fijnheer J; van Gorp L H; Kwee W S; Los J; Peterse H C
The Multicenter Morphometric Mammary Carcinoma Project (MMMCP). A nationwide prospective study on reproducibility and prognostic power of routine quantitative assessments in The Netherlands.
Pathology, research and practice 1989;185(5):664-70.
1989: Baak J P; van Diest P J; Stroet-van Galen C; Wisse-Brekelmans E C; Matze-Cok E; Littooy J G; Kurver P H
Data processing and analysis in the Multicenter Morphometric Mammary Carcinoma Project (MMMCP).
Pathology, research and practice 1989;185(5):657-63.
1989: Jansen W; Baak J P; Smeulders A W; van Ginneken A M
A computer based handbook and atlas of pathology.
Pathology, research and practice 1989;185(5):652-6.
1989: van Diest P J; Risse E K; Schipper N W; Baak J P; Mouriquand J
Comparison of light microscopic grading and morphometric features in cytological breast cancer specimens.
Pathology, research and practice 1989;185(5):612-6.
1989: van Bodegom P C; Wagenaar S S; Corrin B; Baak J P; Berkel J; Vanderschueren R G
Second primary lung cancer: importance of long term follow up.
Thorax 1989;44(10):788-93.
1989: Blomjous C E; Vos W; Schipper N W; De Voogt H J; Baak J P; Meijer C J
Morphometric and flow cytometric analysis of small cell undifferentiated carcinoma of the bladder.
Journal of clinical pathology 1989;42(10):1032-9.
1989: Uyterlinde A M; Smeulders A W; Baak J P
Reproducibility and comparison of quantitative DNA histogram features obtained with a scanning microdensitometer and a flow cytometer in breast cancers.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(5):353-60.
1989: Baak J P; Noteboom E; Koevoets J J
The influence of fixatives and other variations in tissue processing on nuclear morphometric features.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(4):219-24.
1989: van Diest P J; Smeulders A W; Thunnissen F B; Baak J P
Cytomorphometry. A methodologic study of preparation techniques, selection methods and sample sizes.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(4):225-31.
1989: van der Putten H W; Baak J P; Koenders T J; Kurver P H; Stolk H G; Stolte L A
Prognostic value of quantitative pathologic features and DNA content in individual patients with stage I endometrial adenocarcinoma.
Cancer 1989;63(7):1378-87.
1989: Blomjous E C; Schipper N W; Baak J P; Vos W; De Voogt H J; Meijer C J
The value of morphometry and DNA flow cytometry in addition to classic prognosticators in superficial urinary bladder carcinoma.
American journal of clinical pathology 1989;91(3):243-8.
1989: van Thiel T P; van der Linden J C; Baak J P; van de Sandt M M; van Galen C; Bezemer P D
Reproducibility of flow cytometric assessment of follicular tumours of the thyroid.
Journal of clinical pathology 1989;42(3):260-3.
1989: van Bodegom P C; Baak J P; van Galen C; Vanderschueren R G; Wagenaar S S
Quantitative pathologic analysis of first and second primary cancers in double tumors of the lung.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1989;11(1):43-7.
1989: van Bodegom P C; Baak J P; Stroet-van Galen C; Schipper N W; Wisse-Brekelmans E C; Vanderschueren R G; Wagenaar S S
The percentage of aneuploid cells is significantly correlated with survival in accurately staged patients with stage 1 resected squamous cell lung cancer and long-term follow up.
Cancer 1989;63(1):143-7.
1989: van der Wal N; Baak J P; Schipper N W; van der Waal I
Morphometric study of pseudoepitheliomatous hyperplasia in granular cell tumors of the tongue.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1989;18(1):8-10.
1989: Blomjous C E; Schipper N W; Vos W; Baak J P; de Voogt H J; Meijer C J
Comparison of quantitative and classic prognosticators in urinary bladder carcinoma. A multivariate analysis of DNA flow cytometric, nuclear morphometric and clinicopathological features.
Virchows Archiv. A, Pathological anatomy and histopathology 1989;415(5):421-8.
1988: Baak J P
Possibilities and progress of quantitative pathological examination of ovarian tumours.
European journal of obstetrics, gynecology, and reproductive biology 1988;29(3):183-9.
1988: Thunnissen F B; Diegenbach P C; Baak J P; Houthoff H J
The influence of variations in the measuring procedure on quantitative nuclear image features in histologic sections of lung tissue.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1988;10(5):349-54.
1988: Thunnissen F B; Diegenbach P C; Dingemans K P; van Hattum A H; Houthoff H J; Baak J P
The effect of sampling on quantitative nuclear image features in histologic sections of lung carcinomas.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1988;10(5):355-9.
1988: Thunnissen F B; Van Eijk J; Baak J P; Schipper N W; Uyterlinde A M; Breederveld R S; Meijer S
Bronchopulmonary carcinoids and regional lymph node metastases. A quantitative pathologic investigation.
The American journal of pathology 1988;132(1):119-22.
1988: Baak J P; Kurver P H
Development and use of a rule-based pathology expert consultation system.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1988;10(3):214-8.
1988: Baak J P; Schipper N W; Wisse-Brekelmans E C; Ceelen T; Bosman F T; van Geuns H; Wils J
The prognostic value of morphometrical features and cellular DNA content in cis-platin treated late ovarian cancer patients.
British journal of cancer 1988;57(5):503-8.
1988: Fleege J C; Baak J P; Smeulders A W
Analysis of measuring system parameters that influence reproducibility of morphometric assessments with a graphic tablet.
Human pathology 1988;19(5):513-7.
1988: Wils J; van Geuns H; Baak J
Proposal for therapeutic approach based on prognostic factors including morphometric and flow-cytometric features in stage III-IV ovarian cancer.
Cancer 1988;61(9):1920-5.
1988: Seldenrijk C A; Hendriks G; Smeulders A W; Baak J P; van Spreeuwel J P; Meuwissen S G; Meijer C J
Reproducibility of counting immunoglobulin-containing cells in colonic mucosal biopsies.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1988;10(2):94-100.
1988: Baak J P; Nauta J J; Wisse-Brekelmans E C; Bezemer P D
Architectural and nuclear morphometrical features together are more important prognosticators in endometrial hyperplasias than nuclear morphometrical features alone.
The Journal of pathology 1988;154(4):335-41.
1988: Uyterlinde A M; Schipper N W; Baak J P; Peterse H; Matze E
Limited prognostic value of cellular DNA content to classical and morphometrical parameters in invasive ductal breast cancer.
American journal of clinical pathology 1988;89(3):301-7.
1988: Blomjous C E; Schipper N W; Baak J P; van Galen E M; de Voogt H J; Meyer C J
Retrospective study of prognostic importance of DNA flow cytometry of urinary bladder carcinoma.
Journal of clinical pathology 1988;41(1):21-5.
1987: Baak J P; Chan K K; Stolk J G; Kenemans P
Prognostic factors in borderline and invasive ovarian tumors of the common epithelial type.
Pathology, research and practice 1987;182(6):755-74.
1987: Uyterlinde A M; Schipper N W; Baak J P
Comparison of extent of disease and morphometric and DNA flow cytometric prognostic factors in invasive ductal breast cancer.
Journal of clinical pathology 1987;40(12):1432-6.
1987: Baak J P; Wisse-Brekelmans E C; Uyterlinde A M; Schipper N W
Evaluation of the prognostic value of morphometric features and cellular DNA content in FIGO I ovarian cancer patients.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1987;9(4):287-90.

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