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Anthony Joetham

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Yi Jia; Anthony Joetham; Joseph J Lucas; Roland A Marcus; Brian P O'Connor; Katsuyuki Takeda; Junyan Han; Erwin W Gelfand
Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation.
Yoshiki Shiraishi; Katsuyuki Takeda; Joanne Domenico; Yi Jia; Anthony Joetham; Hajime Karasuyama; Erwin W Gelfand
Sequential engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic Rhinitis.
Anthony Joetham; Hiroshi Ohnishi; Masakazu Okamoto; Michaela Schedel; Katsuyuki Takeda; Azzeddine Dakhama; Joanne Domenico; Erwin W Gelfand
Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.

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2013: Yi Jia; Anthony Joetham; Joseph J Lucas; Roland A Marcus; Brian P O'Connor; Katsuyuki Takeda; Junyan Han; Erwin W Gelfand
Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(8):4056-65.
2013: Yoshiki Shiraishi; Katsuyuki Takeda; Joanne Domenico; Yi Jia; Anthony Joetham; Hajime Karasuyama; Erwin W Gelfand
Sequential engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic Rhinitis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(2):539-48.
2012: Anthony Joetham; Hiroshi Ohnishi; Masakazu Okamoto; Michaela Schedel; Katsuyuki Takeda; Azzeddine Dakhama; Joanne Domenico; Erwin W Gelfand
Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.
The Journal of biological chemistry 2012;287(21):17100-8.
2011: Lisa K Peterson; Laura A Shaw; Anthony Joetham; Shimon Sakaguchi; Erwin W Gelfand; Leonard L Dragone
SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):2273-81.
2011: Anthony Joetham; Masakazu Okamoto; Katsuyuki Takeda; Michaela Schedel; Hiroshi Ohnishi; Azzeddine Dakhama; Erwin W Gelfand
CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):113-20.
2010: Meiqin Wang; Katsuyuki Takeda; Yoshiki Shiraishi; Masakazu Okamoto; Azzeddine Dakhama; Anthony Joetham; Erwin W Gelfand
Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway.
The Journal of allergy and clinical immunology 2010;126(2):306-16, 316.e1-12.
2010: Katsuyuki Takeda; Y Shiraishi; Shigeki Matsubara; Nobuaki Miyahara; H Matsuda; M Okamoto; Anthony Joetham; Erwin W Gelfand
Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation.
British journal of pharmacology 2010;160(6):1399-407.
2009: Masakazu Okamoto; Hiroyuki Matsuda; Anthony Joetham; Joseph J Lucas; Joanne Domenico; Koji Yasutomo; Katsuyuki Takeda; Erwin W Gelfand
Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):2995-3003.
2009: Anthony Joetham; Katsuyuki Takeda; Masakazu Okamoto; Christian Taube; Hiroyuki Matsuda; Azzeddine Dakhama; Erwin W Gelfand
Antigen specificity is not required for modulation of lung allergic responses by naturally occurring regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):1821-7.
2009: Katsuyuki Takeda; Steven W Dow; Nobuaki Miyahara; Taku Kodama; Toshiyuki Koya; Christian Taube; Anthony Joetham; Jung-Won Park; Azzeddine Dakhama; Ross M Kedl; Erwin W Gelfand
Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):181-90.
2009: Nobuaki Miyahara; Hiroshi Ohnishi; Satoko Miyahara; Katsuyuki Takeda; Shigeki Matsubara; Hiroyuki Matsuda; Masakazu Okamoto; Joan E Loader; Anthony Joetham; Mitsune Tanimoto; Azzeddine Dakhama; Erwin W Gelfand
Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation.
American journal of respiratory cell and molecular biology 2009;40(6):672-82.
2009: Shigeki Matsubara; Katsuyuki Takeda; Niyun Jin; Masakazu Okamoto; Hiroyuki Matsuda; Yoshiki Shiraishi; Jung Won Park; Glen McConville; Anthony Joetham; Rebecca L O'Brien; Azzeddine Dakhama; Willi K Born; Erwin W Gelfand
Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness.
American journal of respiratory cell and molecular biology 2009;40(4):454-63.
2008: Anthony Joetham; Shigeki Matsubara; Masakazu Okamoto; Katsuyuki Takeda; Nobuaki Miyahara; Azzeddine Dakhama; Erwin W Gelfand
Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7117-24.
2008: Masakazu Okamoto; Katsuyuki Takeda; Anthony Joetham; Hiroshi Ohnishi; Hiroyuki Matsuda; Christina H Swasey; Bradley J Swanson; Koji Yasutomo; Azzeddine Dakhama; Erwin W Gelfand
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.
The Journal of experimental medicine 2008;205(5):1087-97.
2008: Shigeki Matsubara; Christina H Swasey; Joan E Loader; Azzeddine Dakhama; Anthony Joetham; Hiroshi Ohnishi; Annette Balhorn; Nobuaki Miyahara; Katsuyuki Takeda; Erwin W Gelfand
Estrogen determines sex differences in airway responsiveness after allergen exposure.
American journal of respiratory cell and molecular biology 2008;38(5):501-8.
2008: Satoko Miyahara; Nobuaki Miyahara; Joseph J Lucas; Anthony Joetham; Shikegi Matsubara; Hiroshi Ohnishi; Azzeddine Dakhama; Erwin W Gelfand
Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses.
The Journal of allergy and clinical immunology 2008;121(3):718-24.
2008: Young-Mok Lee; Nobuaki Miyahara; Katsuyuki Takeda; John Prpich; Anita Oh; Annette Balhorn; Anthony Joetham; Erwin W Gelfand; Azzeddine Dakhama
IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
American journal of respiratory and critical care medicine 2008;177(2):208-18.
2007: Anthony Joetham; Katsuyuki Takeda; Nobuaki Miyahara; Shigeki Matsubara; Hiroshi Ohnishi; Toshiyuki Koya; Azzeddine Dakhama; Erwin W Gelfand
Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(38):15057-62.
2007: Shigeki Matsubara; Katsuyuki Takeda; Taku Kodama; Anthony Joetham; Nobuaki Miyahara; Toshiyuki Koya; Christina H Swasey; Masakazu Okamoto; Azzeddine Dakhama; Erwin W Gelfand
IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells.
American journal of respiratory cell and molecular biology 2007;36(3):324-32.
2007: Anthony Joetham; Katsuyuki Takeda; Katsuyuki Takada; Christian Taube; Nobuaki Miyahara; Shigeki Matsubara; Satoko Matsubara; Toshiyuki Koya; Yeong Ho Rha; Azzeddine Dakhama; Erwin W Gelfand
Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1433-42.
2006: Toshiyuki Koya; Katsuyuki Takeda; Taku Kodama; Nobuaki Miyahara; Shigeki Matsubara; Annette Balhorn; Anthony Joetham; Azzeddine Dakhama; Erwin W Gelfand
RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge.
American journal of respiratory cell and molecular biology 2006;35(2):147-54.
2006: Christian Taube; Joshua M Thurman; Katsuyuki Takeda; Anthony Joetham; Nobuaki Miyahara; Michael C Carroll; Azzeddine Dakhama; Patricia C Giclas; V Michael Holers; Erwin W Gelfand
Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8084-9.
2006: Shigeki Matsubara; Toshiyuki Koya; Katsuyuki Takeda; Anthony Joetham; Nobuaki Miyahara; Polly Pine; Esteban S Masuda; Christina H Swasey; Erwin W Gelfand
Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation.
American journal of respiratory cell and molecular biology 2006;34(4):426-33.
2006: Toshiyuki Koya; Taku Kodama; Katsuyuki Takeda; Nobuaki Miyahara; Eun-Seok Yang; Christian Taube; Anthony Joetham; Jung-Won Park; Azzeddine Dakhama; Erwin W Gelfand
Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure.
American journal of respiratory and critical care medicine 2006;173(1):42-55.
2005: Satoko Miyahara; Nobuaki Miyahara; Katsuyuki Takeda; Anthony Joetham; Erwin W Gelfand
Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI).
The Journal of allergy and clinical immunology 2005;116(5):1020-7.
2005: Azzeddine Dakhama; Jung-Won Park; Christian Taube; Anthony Joetham; Annette Balhorn; Nobuaki Miyahara; Katsuyuki Takeda; Erwin W Gelfand
The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1876-83.
2005: Nobuaki Miyahara; Katsuyuki Takeda; Satoko Miyahara; Shigeki Matsubara; Toshiyuki Koya; Anthony Joetham; Elangovan Krishnan; Azzeddine Dakhama; Haribabu Bodduluri; Erwin W Gelfand
Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2005;172(2):161-7.
2005: Anthony Joetham; Katsuyuki Takeda; Christian Taube; Nobuaki Miyahara; Arihiko Kanehiro; Azzeddine Dakhama; Erwin W Gelfand
Airway hyperresponsiveness in the absence of CD4+ T cells after primary but not secondary challenge.
American journal of respiratory cell and molecular biology 2005;33(1):89-96.
2005: Nobuaki Miyahara; Katsuyuki Takeda; Satoko Miyahara; Christian Taube; Anthony Joetham; Toshiyuki Koya; Shigeki Matsubara; Azzeddine Dakhama; Andrew M Tager; Andrew D Luster; Erwin W Gelfand
Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4979-84.
2005: Azzeddine Dakhama; Jung-Won Park; Christian Taube; Mohamed El Gazzar; Taku Kodama; Nobuaki Miyahara; Katsuyuki Takeda; Arihiko Kanehiro; Annette Balhorn; Anthony Joetham; Joan E Loader; Gary L Larsen; Erwin W Gelfand
Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection.
American journal of physiology. Lung cellular and molecular physiology 2005;288(4):L761-70.
2004: Azzeddine Dakhama; Jung-Won Park; Christian Taube; Kosuke Chayama; Annette Balhorn; Anthony Joetham; Xu-Dong Wei; Rhi-Hua Fan; Christina H Swasey; Nobuaki Miyahara; Taku Kodama; Alberto Alvarez; Katsuyuki Takeda; Erwin W Gelfand
The role of virus-specific immunoglobulin E in airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2004;170(9):952-9.
2004: Erwin W Gelfand; Anthony Joetham; Zhi-Hua Cui; Annette Balhorn; Katsuyuki Takeda; Christian Taube; Azzeddine Dakhama
Induction and maintenance of airway responsiveness to allergen challenge are determined at the age of initial sensitization.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1298-306.
2004: Jung-Won Park; Christian Taube; Christina H Swasey; Taku Kodama; Anthony Joetham; Annette Balhorn; Katsuyuki Takeda; Nobuaki Miyahara; Corrie B Allen; Azzeddine Dakhama; Soo-Hyun Kim; Charles A Dinarello; Erwin W Gelfand
Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.
American journal of respiratory cell and molecular biology 2004;30(6):830-6.
2004: Christian Taube; Jerry A Nick; Britta Siegmund; Catherine Duez; Katsuyuki Takeda; Yeong Ho Rha; Jung-Won Park; Anthony Joetham; Katie R Poch; Azzeddine Dakhama; Charles A Dinarello; Erwin W Gelfand
Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness.
American journal of respiratory cell and molecular biology 2004;30(6):837-43.
2004: Christian Taube; Xudong Wei; Christina H Swasey; Anthony Joetham; Simona Zarini; Tricia Lively; Katsuyuki Takeda; Joan E Loader; Nobuaki Miyahara; Taku Kodama; Leonard D Shultz; Debra D Donaldson; Eckard H Hamelmann; Azzeddine Dakhama; Erwin W Gelfand
Mast cells, Fc epsilon RI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6398-406.
2004: Jung-Won Park; Christian Taube; Anthony Joetham; Katsuyuki Takeda; Taku Kodama; Azzeddine Dakhama; Glen McConville; Corrie B Allen; Georgia Sfyroera; Leonard D Shultz; John D Lambris; Patricia C Giclas; V Michael Holers; Erwin W Gelfand
Complement activation is critical to airway hyperresponsiveness after acute ozone exposure.
American journal of respiratory and critical care medicine 2004;169(6):726-32.
2004: Nobuaki Miyahara; Katsuyuki Takeda; Taku Kodama; Anthony Joetham; Christian Taube; Jung-Won Park; Satoko Miyahara; Annette Balhorn; Azzeddine Dakhama; Erwin W Gelfand
Contribution of antigen-primed CD8+ T cells to the development of airway hyperresponsiveness and inflammation is associated with IL-13.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2549-58.
2003: Jung Won Park; Christian Taube; Eun-Seok Yang; Anthony Joetham; Annette Balhorn; Katsuyuki Takeda; Nobuaki Miyahara; Azzeddine Dakhama; Debra D Donaldson; Erwin W Gelfand
Respiratory syncytial virus-induced airway hyperresponsiveness is independent of IL-13 compared with that induced by allergen.
The Journal of allergy and clinical immunology 2003;112(6):1078-87.
2003: Zhi-Hua Cui; Anthony Joetham; M Kemal Aydintug; Youn-Soo Hahn; Willi K Born; Erwin W Gelfand
Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells.
American journal of respiratory and critical care medicine 2003;168(11):1324-32.
2003: Christian Taube; Yeong Ho Rha; Katsuyuki Takeda; Jung-Won Park; Anthony Joetham; Annette Balhorn; Azzeddine Dakhama; Patricia C Giclas; V Michael Holers; Erwin W Gelfand
Inhibition of complement activation decreases airway inflammation and hyperresponsiveness.
American journal of respiratory and critical care medicine 2003;168(11):1333-41.
2003: Mika J Mäkelä; Ralph A Tripp; Azzeddine Dakhama; Jun-Won Park; Toshihide Ikemura; Anthony Joetham; Matti Waris; Larry J Anderson; Erwin W Gelfand
Prior airway exposure to allergen increases virus-induced airway hyperresponsiveness.
The Journal of allergy and clinical immunology 2003;112(5):861-9.
2003: Erwin W Gelfand; Zhi-Hua Cui; Katsuyuki Takeda; Arihiko Kanehiro; Anthony Joetham
Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.
The Journal of allergy and clinical immunology 2003;112(4 Suppl):S89-95.
2003: Xudong Wei; Weiyong Sun; Ruihua Fan; Joanne Hahn; Anthony Joetham; Guiming Li; Saiphone Webb; Timothy Garrington; Azzeddine Dakhama; Joseph Lucas; Gary L Johnson; Erwin W Gelfand
MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells.
European journal of immunology 2003;33(10):2903-9.
2003: Katsuyuki Takeda; Nobuaki Miyahara; Yeong Ho Rha; Christian Taube; Eun-Seok Yang; Anthony Joetham; Taku Kodama; Annette Balhorn; Azzeddine Dakhama; Catherine Duez; Amanda J Evans; Dennis R Voelker; Erwin W Gelfand
Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function.
American journal of respiratory and critical care medicine 2003;168(7):783-9.
2003: Christian Taube; Azzeddine Dakhama; Yeong Ho Rha; Katsuyuki Takeda; Anthony Joetham; Jung-Won Park; Annette Balhorn; Toshiyuki Takai; Katie R Poch; Jerry A Nick; Erwin W Gelfand
Transient neutrophil infiltration after allergen challenge is dependent on specific antibodies and Fc gamma III receptors.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4301-9.
2002: Yeong Ho Rha; Christian Taube; Angela Haczku; Anthony Joetham; Katsuyuki Takeda; Catherine Duez; Marvin Siegel; M Kemal Aydintug; Willi K Born; Azzeddine Dakhama; Erwin W Gelfand
Effect of microbial heat shock proteins on airway inflammation and hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5300-7.
2002: Arihiko Kanehiro; Michael Lahn; Mika J Mäkelä; Azzeddine Dakhama; Anthony Joetham; Yeong Ho Rha; Willi K Born; Erwin W Gelfand
Requirement for the p75 TNF-alpha receptor 2 in the regulation of airway hyperresponsiveness by gamma delta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4190-7.
2002: Erwin W Gelfand; Zhi-Hua Cui; Katsuyuki Takeda; Arihiko Kanehiro; Anthony Joetham
Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.
The Journal of allergy and clinical immunology 2002;110(1):85-95.
2002: Mika J Mäkelä; Arihiko Kanehiro; Azzeddine Dakhama; Larry Borish; Anthony Joetham; Ralph A Tripp; Larry Anderson; Erwin W Gelfand
The failure of interleukin-10-deficient mice to develop airway hyperresponsiveness is overcome by respiratory syncytial virus infection in allergen-sensitized/challenged mice.
American journal of respiratory and critical care medicine 2002;165(6):824-31.
2001: Arihiko Kanehiro; Michael Lahn; Mika J Mäkelä; Azzeddine Dakhama; M Fujita; Anthony Joetham; Robert J Mason; Willi K Born; Erwin W Gelfand
Tumor necrosis factor-alpha negatively regulates airway hyperresponsiveness through gamma-delta T cells.
American journal of respiratory and critical care medicine 2001;164(12):2229-38.
2001: Adrian Tomkinson; Catherine Duez; Grzegorz Cieslewicz; JC Pratt; Anthony Joetham; M C Shanafelt; R Gundel; Erwin W Gelfand
A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(9):5792-800.
2001: Arihiko Kanehiro; Toshihide Ikemura; Mika J Mäkelä; Michael Lahn; Anthony Joetham; Azzeddine Dakhama; Erwin W Gelfand
Inhibition of phosphodiesterase 4 attenuates airway hyperresponsiveness and airway inflammation in a model of secondary allergen challenge.
American journal of respiratory and critical care medicine 2001;163(1):173-84.
2000: Arihiko Kanehiro; Katsuyuki Takeda; Anthony Joetham; Adrian Tomkinson; Toshihide Ikemura; Charles G Irvin; Erwin W Gelfand
Timing of administration of anti-VLA-4 differentiates airway hyperresponsiveness in the central and peripheral airways in mice.
American journal of respiratory and critical care medicine 2000;162(3 Pt 1):1132-9.
2000: J Schwarze; Grzegorz Cieslewicz; Anthony Joetham; Toshihide Ikemura; Mika J Mäkelä; Azzeddine Dakhama; Leonard D Shultz; M C Lamers; Erwin W Gelfand
Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):380-6.
2000: Gary L Larsen; Carl W White; Katsuyuki Takeda; Joan E Loader; Dee Dee Nguyen; Anthony Joetham; Y Groner; Erwin W Gelfand
Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control.
American journal of physiology. Lung cellular and molecular physiology 2000;279(2):L350-9.
2000: Toshihide Ikemura; J Schwarze; M Makela; Arihiko Kanehiro; Anthony Joetham; K Ohmori; Erwin W Gelfand
Type 4 phosphodiesterase inhibitors attenuate respiratory syncytial virus-induced airway hyper-responsiveness and lung eosinophilia.
The Journal of pharmacology and experimental therapeutics 2000;294(2):701-6.
2000: Mika J Mäkelä; Arihiko Kanehiro; Larry Borish; Azzeddine Dakhama; Joan E Loader; Anthony Joetham; Zhou Xing; Manel Jordana; Gary L Larsen; Erwin W Gelfand
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6007-12.
2000: Angela Haczku; Katsuyuki Takeda; Eckard H Hamelmann; Joan E Loader; Anthony Joetham; I Redai; Charles G Irvin; James J Lee; H Kikutani; D Conrad; Erwin W Gelfand
CD23 exhibits negative regulatory effects on allergic sensitization and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2000;161(3 Pt 1):952-60.
1999: J Schwarze; M Mäkelä; Grzegorz Cieslewicz; Azzeddine Dakhama; Michael Lahn; Toshihide Ikemura; Anthony Joetham; Erwin W Gelfand
Transfer of the enhancing effect of respiratory syncytial virus infection on subsequent allergic airway sensitization by T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5729-34.
1999: Adrian Tomkinson; Arihiko Kanehiro; Nathan Rabinovitch; Anthony Joetham; Grzegorz Cieslewicz; Erwin W Gelfand
The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5.
American journal of respiratory and critical care medicine 1999;160(4):1283-91.
1999: Michael Lahn; Arihiko Kanehiro; Katsuyuki Takeda; Anthony Joetham; J Schwarze; G Köhler; R O'Brien; Erwin W Gelfand; Willi K Born; A Kanehio
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells.
Nature medicine 1999;5(10):1150-6.
1999: Eckard H Hamelmann; Grzegorz Cieslewicz; J Schwarze; T Ishizuka; Anthony Joetham; C Heusser; Erwin W Gelfand
Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 1999;160(3):934-41.
1999: Angela Haczku; Katsuyuki Takeda; I Redai; Eckard H Hamelmann; Grzegorz Cieslewicz; Anthony Joetham; Joan E Loader; James J Lee; C Irvin; Erwin W Gelfand
Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1638-43.
1999: J Schwarze; Grzegorz Cieslewicz; Anthony Joetham; Toshihide Ikemura; Eckard H Hamelmann; Erwin W Gelfand
CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4207-11.
1999: J Schwarze; Grzegorz Cieslewicz; Eckard H Hamelmann; Anthony Joetham; Leonard D Shultz; M C Lamers; Erwin W Gelfand
IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2997-3004.
1998: J Schwarze; Grzegorz Cieslewicz; Anthony Joetham; L K Sun; W N Sun; T W Chang; Eckard H Hamelmann; Erwin W Gelfand
Antigen-specific immunoglobulin-A prevents increased airway responsiveness and lung eosinophilia after airway challenge in sensitized mice.
American journal of respiratory and critical care medicine 1998;158(2):519-25.
1998: J Schwarze; Eckard H Hamelmann; Grzegorz Cieslewicz; Adrian Tomkinson; Anthony Joetham; K Bradley; Erwin W Gelfand
Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice.
The Journal of allergy and clinical immunology 1998;102(1):86-93.
1997: Angela Haczku; Katsuyuki Takeda; Eckard H Hamelmann; A Oshiba; Joan E Loader; Anthony Joetham; C Irvin; H Kikutani; Erwin W Gelfand
CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin.
American journal of respiratory and critical care medicine 1997;156(6):1945-55.
1997: Katsuyuki Takeda; Eckard H Hamelmann; Anthony Joetham; Leonard D Shultz; Gary L Larsen; Charles G Irvin; Erwin W Gelfand
Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice.
The Journal of experimental medicine 1997;186(3):449-54.