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Kyung Johanson

Research Profile

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

Procedures

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Protein Binding

Physiology

Leukocyte Chemotaxis

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Publications

TOP 3
Gustavo Arruda Bezerra; Alexey Bochkarev; Doug Cossar; Lissete Crombett; Elena Dobrovetsky; Aiping Dong; Karl Gruber; Annie M Hassell; Kyung O Johanson; Karen M Kennedy-Wilson; Patrick J McDevitt; Almagul Seitova; Lisa M Shewchuk; Sharon M Sweitzer; Thomas D Sweitzer; Sirano Dhe-Paganon
Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.
Josh Cottom; Glenn Hofmann; Brett Siegfried; Jingsong Yang; Hong Zhang; Tracey Yi; Thau F Ho; Chad Quinn; Da-Yuan Wang; Kyung O Johanson; Robert S Ames; Hu Li
Assay development and high-throughput screening of small molecular c-Abl kinase activators.
Quinn Lu; Matthew C Burns; Patrick J McDevitt; Taylor L Graham; Abby J Sukman; James A Fornwald; Xiaoyan Tang; Kathleen T Gallagher; Gerald E Hunsberger; James J Foley; Dulcie B Schmidt; John J Kerrigan; Tia S Lewis; Robert S Ames; Kyung O Johanson
Optimized procedures for producing biologically active chemokines.

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All Publications

2012: Gustavo Arruda Bezerra; Alexey Bochkarev; Doug Cossar; Lissete Crombett; Elena Dobrovetsky; Aiping Dong; Karl Gruber; Annie M Hassell; Kyung O Johanson; Karen M Kennedy-Wilson; Patrick J McDevitt; Almagul Seitova; Lisa M Shewchuk; Sharon M Sweitzer; Thomas D Sweitzer; Sirano Dhe-Paganon
Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.
PloS one 2012;7(8):e43019.
2011: Josh Cottom; Glenn Hofmann; Brett Siegfried; Jingsong Yang; Hong Zhang; Tracey Yi; Thau F Ho; Chad Quinn; Da-Yuan Wang; Kyung O Johanson; Robert S Ames; Hu Li
Assay development and high-throughput screening of small molecular c-Abl kinase activators.
Journal of biomolecular screening 2011;16(1):53-64.
2009: Quinn Lu; Matthew C Burns; Patrick J McDevitt; Taylor L Graham; Abby J Sukman; James A Fornwald; Xiaoyan Tang; Kathleen T Gallagher; Gerald E Hunsberger; James J Foley; Dulcie B Schmidt; John J Kerrigan; Tia S Lewis; Robert S Ames; Kyung O Johanson
Optimized procedures for producing biologically active chemokines.
Protein expression and purification 2009;65(2):251-60.
2008: John J Kerrigan; Dean E McNulty; Matthew Burns; Kimberly E Allen; Xiaoyan Tang; Quinn Lu; Janice M Trulli; Kyung O Johanson; James F Kane
Frameshift events associated with the lysyl-tRNA and the rare arginine codon, AGA, in Escherichia coli: a case study involving the human Relaxin 2 protein.
Protein expression and purification 2008;60(2):110-6.
2007: Monique F Murray; Anthony Jurewicz; John D Martin; Thau F Ho; Hong Zhang; Kyung O Johanson; Robert B Kirkpatrick; Jianhong Ma; Leng A Lor; Sara H Thrall; Benjamin Schwartz
A high-throughput screen measuring ubiquitination of p53 by human mdm2.
Journal of biomolecular screening 2007;12(8):1050-8.
2006: Robert B Kirkpatrick; Michael Grooms; Feilan Wang; Heather Fenderson; John Feild; Michael A Pratta; Craig Volker; Gilbert Scott; Kyung O Johanson
Bacterial production of biologically active canine interleukin-1beta by seamless SUMO tagging and removal.
Protein expression and purification 2006;50(1):102-10.
2006: Jianhong Ma; John D Martin; Hong Zhang; Kurt R Auger; Thau F Ho; Robert B Kirkpatrick; Michael Grooms; Kyung O Johanson; Peter J Tummino; Robert Copeland; Zhihong Lai
A second p53 binding site in the central domain of Mdm2 is essential for p53 ubiquitination.
Biochemistry 2006;45(30):9238-45.
2006: Lata T Gooljarsingh; Christine Fernandes; Kang Yan; Hong Zhang; Michael Grooms; Kyung O Johanson; Robert H Sinnamon; Robert B Kirkpatrick; John Kerrigan; Tia Lewis; Marc Arnone; Alastair J King; Zhihong Lai; Robert Copeland; Peter J Tummino
A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7625-30.
2005: Lara S Kallander; Qing Lu; Wenfang Chen; Thaddeus Tomaszek; Guang Yang; David Tew; Thomas D Meek; Glenn Hofmann; Christina K Schulz-Pritchard; Ward W Smith; Cheryl A Janson; M Dominic Ryan; Gui-Feng Zhang; Kyung O Johanson; Robert B Kirkpatrick; Thau F Ho; Paul W Fisher; Michael R Mattern; Randall K Johnson; Michael Hansbury; James D Winkler; Keith W Ward; Daniel F Veber; Scott K Thompson
4-Aryl-1,2,3-triazole: a novel template for a reversible methionine aminopeptidase 2 inhibitor, optimized to inhibit angiogenesis in vivo.
Journal of medicinal chemistry 2005;48(18):5644-7.
2005: Sandhya S Nerurkar; Patrick J McDevitt; Gilbert F Scott; Kyung O Johanson; Robert N Willette; Tian-Li Yue
Lipopolysaccharide (LPS) contamination plays the real role in C-reactive protein-induced IL-6 secretion from human endothelial cells in vitro.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):e136.
2003: Erding Hu; Edward Dul; Chiu-Mei Sung; Zunxuan Chen; Robert B Kirkpatrick; Gui-Feng Zhang; Kyung O Johanson; Ronggang Liu; Amparo Lago; Glenn Hofmann; Ricardo Macarron; Maite de los Frailes; Paloma Perez; John A Krawiec; James Winkler; Michael Jaye
Identification of novel isoform-selective inhibitors within class I histone deacetylases.
The Journal of pharmacology and experimental therapeutics 2003;307(2):720-8.
2003: William H Miller; Peter J Manley; Russell D Cousins; Karl F Erhard; Dirk A Heerding; Chet Kwon; Stephen T Ross; James Samanen; Dennis T Takata; Irene N Uzinskas; Catherine C K Yuan; R Curtis Haltiwanger; Catherine J Gress; Michael W Lark; Shing-Mei Hwang; Ian E James; David J Rieman; Robert N Willette; Tian-Li Yue; Leonard M Azzarano; Kevin L Salyers; Brian R Smith; Keith W Ward; Kyung O Johanson; William F Huffman
Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin alphavbeta3) antagonists.
Bioorganic & medicinal chemistry letters 2003;13(8):1483-6.
2003: Robert B Kirkpatrick; Patrick J McDevitt; Rosalie E Matico; Silas Nwagwu; Stephen Trulli; Joyce Mao; Dwight D Moore; Adam F Yorke; Megan M McLaughlin; Kristin A Knecht; Louis C Elefante; Amy S Calamari; Jim A Fornwald; John J Trill; Zdenka L Jonak; James Kane; Pramathesh S Patel; Ganesh M Sathe; Allan R Shatzman; Peter M Tapley; Kyung O Johanson
A bicistronic expression system for bacterial production of authentic human interleukin-18.
Protein expression and purification 2003;27(2):279-92.
2002: Zunxuan Chen; Steven Clark; Marian Birkeland; Chiu-Mei Sung; Amparo Lago; Ronggang Liu; Robert B Kirkpatrick; Kyung O Johanson; James D Winkler; Erding Hu
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells.
Cancer letters 2002;188(1-2):127-40.
2002: Baoguang Zhao; Michael J Bower; Patrick J McDevitt; Huizhen Zhao; Stephen T Davis; Kyung O Johanson; Susan M Green; Nestor O Concha; Bin-Bing S Zhou
Structural basis for Chk1 inhibition by UCN-01.
The Journal of biological chemistry 2002;277(48):46609-15.
2002: Zdenka L Jonak; Stephen Trulli; Curtis Maier; Francis L McCabe; Robert B Kirkpatrick; Kyung O Johanson; Yen Sen Ho; Louis C Elefante; Yi-Jiun Chen; Danuta J Herzyk; Michael T Lotze; Randall K Johnson
High-dose recombinant interleukin-18 induces an effective Th1 immune response to murine MOPC-315 plasmacytoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25 Suppl 1():S20-7.
2001: Xiayang Qiu; Cheryl A Janson; Ward W Smith; S M Green; Patrick J McDevitt; Kyung O Johanson; P Carter; Martin J Hibbs; C Lewis; A Chalker; Andrew P Fosberry; JM LaLonde; John M Berge; Pamela Brown; Catherine S V Houge-Frydrych; Richard L Jarvest
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein science : a publication of the Protein Society 2001;10(10):2008-16.
2001: Guang Yang; Robert B Kirkpatrick; T Ho; G F Zhang; P H Liang; Kyung O Johanson; David J Casper; Michael Doyle; Joseph P Marino; Scott K Thompson; W Chen; David Tew; Thomas D Meek
Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2).
Biochemistry 2001;40(35):10645-54.
2000: Erding Hu; Zunxuan Chen; TA Fredrickson; Yuan Zhu; Robert B Kirkpatrick; G F Zhang; Kyung O Johanson; Chiu-Mei Sung; Ronggang Liu; J Winkler
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.
The Journal of biological chemistry 2000;275(20):15254-64.
2000: Andrew G King; Kyung O Johanson; C L Frey; P L DeMarsh; John White; Patrick J McDevitt; Dean E McNulty; J Balcarek; Zdenka L Jonak; Pradip Bhatnagar; Louis M Pelus
Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3774-82.
1999: Y Q Qian; Kyung O Johanson; Patrick J McDevitt
Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8.
Journal of molecular biology 1999;294(5):1065-72.
1999: Chang H Kim; Louis M Pelus; Edward R Appelbaum; Kyung O Johanson; N Anzai; Hal E Broxmeyer
CCR7 ligands, SLC/6Ckine/Exodus2/TCA4 and CKbeta-11/MIP-3beta/ELC, are chemoattractants for CD56(+)CD16(-) NK cells and late stage lymphoid progenitors.
Cellular immunology 1999;193(2):226-35.
1998: Colin H Macphee; Edward R Appelbaum; Kyung O Johanson; Kitty E Moores; CS Imburgia; James A Fornwald; Theo A Berkhout; ME Brawner; Pieter Groot; K O'Donnell; DJ O'Shannessy; G Scott; John White
Identification of a truncated form of the CC chemokine CK beta-8 demonstrating greatly enhanced biological activity.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6273-9.
1998: Chang H Kim; Louis M Pelus; John White; E Applebaum; Kyung O Johanson; Hal E Broxmeyer
CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2418-24.
1997: John White; CS Imburgia; Edward Dul; Edward R Appelbaum; K O'Donnell; DJ O'Shannessy; ME Brawner; James A Fornwald; John E Adamou; Nabil A Elshourbagy; K Kaiser; James J Foley; Dulcie B Schmidt; Kyung O Johanson; Colin H Macphee; Kitty E Moores; Dean E McNulty; Gilbert F Scott; R P Schleimer; Henry M Sarau
Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils.
Journal of leukocyte biology 1997;62(5):667-75.
1996: A Wong; Shing-Mei Hwang; P McDevitt; Dean E McNulty; JM Stadel; Kyung O Johanson
Studies on alpha v beta 3/ligand interactions using a [3H]SK&F-107260 binding assay.
Molecular pharmacology 1996;50(3):529-37.
1995: Kyung O Johanson; Edward R Appelbaum; Michael Doyle; Preston Hensley; B Zhao; S S Abdel-Meguid; P Young; R Cook; S Carr; R Matico
Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional studies of Drosophila-expressed recombinant proteins.
The Journal of biological chemistry 1995;270(16):9459-71.
1994: Tian-Li Yue; P J McKenna; Eliot ohlstein; M C Farach-Carson; W T Butler; Kyung O Johanson; P McDevitt; Giora Z Feuerstein; JM Stadel
Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin.
Experimental cell research 1994;214(2):459-64.
1994: TA Morton; D B Bennett; Edward R Appelbaum; D M Cusimano; Kyung O Johanson; R E Matico; Peter Young; Michael Doyle; I M Chaiken
Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.
Journal of molecular recognition : JMR 1994;7(1):47-55.