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A Johns

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TOP 3
Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Robert John Rodgers
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S.
Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Phillip Jeffrey; Scott G Summerfield; Robert John Rodgers
Anorexia and weight loss in male rats 24 h following single dose treatment with orexin-1 receptor antagonist SB-334867.
Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Robert John Rodgers
Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats.

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All Publications

2005: Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Robert John Rodgers
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S.
Behavioural brain research 2005;160(1):11-24.
2005: Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Phillip Jeffrey; Scott G Summerfield; Robert John Rodgers
Anorexia and weight loss in male rats 24 h following single dose treatment with orexin-1 receptor antagonist SB-334867.
Behavioural brain research 2005;157(2):331-41.
2004: Y Ishii; John E Blundell; Jason C G Halford; Neil Upton; R Porter; A Johns; Robert John Rodgers
Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats.
Physiology & behavior 2004;81(1):129-40.
2001: Rod A Porter; WN Chan; Steven Coulton; A Johns; Michael S Hadley; K Widdowson; Jeffrey C Jerman; Stephen J Brough; Martin Coldwell; Darren Smart; FR Jewitt; Phillip Jeffrey; Nigel E Austin
1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor.
Bioorganic & medicinal chemistry letters 2001;11(14):1907-10.
2001: Sharon Bingham; Philip T Davey; A J Babbs; Elaine A Irving; MJ Sammons; M Wyles; Phillip Jeffrey; Leanne Cutler; I Riba; A Johns; Rod A Porter; Neil Upton; A Jackie Hunter; Andrew A Parsons
Orexin-A, an hypothalamic peptide with analgesic properties.
Pain 2001;92(1-2):81-90.
2001: Robert John Rodgers; Jason C G Halford; Ricardo Luiz Nunes-de-Souza; Azair Canto-de-Souza; DC Piper; Jonathan R S Arch; Neil Upton; Rod A Porter; A Johns; John E Blundell
SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats.
The European journal of neuroscience 2001;13(7):1444-52.
2001: Darren Smart; C Sabido-David; Stephen J Brough; FR Jewitt; A Johns; Rod A Porter; Jeffrey C Jerman
SB-334867-A: the first selective orexin-1 receptor antagonist.
British journal of pharmacology 2001;132(6):1179-82.
2001: Declan N C Jones; Jane E Gartlon; F Parker; SG Taylor; Carol Routledge; P Hemmati; Richard Munton; Tracey E Ashmeade; Jonathan P Hatcher; A Johns; Rod A Porter; James Hagan; A Jackie Hunter; Neil Upton
Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity.
Psychopharmacology 2001;153(2):210-8.
2001: Mark S Duxon; J Stretton; Kathryn R Starr; Declan N C Jones; Vicky Holland; Graham Riley; Jeffrey C Jerman; Stephen J Brough; Darren Smart; A Johns; W Chan; Rod A Porter; Neil Upton
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement.
Psychopharmacology 2001;153(2):203-9.
2000: Andrea C Haynes; B Jackson; Helen Chapman; Moh Tadayyon; A Johns; Rod A Porter; Jonathan R S Arch
A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.
Regulatory peptides 2000;96(1-2):45-51.
1999: Nigel E Austin; KY Avenell; Izzy Boyfield; Clive L Branch; Martin Coldwell; Michael S Hadley; Phillip Jeffrey; A Johns; Christopher N Johnson; David J Nash; Graham J Riley; Stephen A Smith; RC Stacey; Geoffrey Stemp; Kevin M Thewlis; Antonio K K Vong
Novel 1,2,3,4-tetrahydroisoquinolines with high affinity and selectivity for the dopamine D3 receptor.
Bioorganic & medicinal chemistry letters 1999;9(2):179-84.