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Akemichi Baba

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Chung-Chuan Chou; Yen Chu; Hui-Ling Lee; Toshio Matsuda; Ming-Shien Wen; Akemichi Baba; Po-Cheng Chang; San-Jou Yeh; Delon Wu
Effects of SEA0400 on Arrhythmogenicity in a Langendorff-Perfused 1-Month Myocardial Infarction Rabbit Model.
Yukio Ago; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Atsuko Hayata-Takano; Keisuke Hazama; Naoki Hiramatsu; Toshihiro Ishihama; Toshiyuki Kawasaki; Atsuro Nakazato; Hirotaka Onoe; Yasuhiro Shibasaki; Norihito Shintani; Kazuhiro Takuma; Toshio Matsuda
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide.
Yukio Ago; Ryota Araki; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Naoki Hiramatsu; Toshiyuki Kawasaki; Yuki Kita; Atsuro Nakazato; Hirotaka Onoe; Kazuhiro Takuma; Koji Yano; Toshio Matsuda
Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice.

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2013: Chung-Chuan Chou; Yen Chu; Hui-Ling Lee; Toshio Matsuda; Ming-Shien Wen; Akemichi Baba; Po-Cheng Chang; San-Jou Yeh; Delon Wu
Effects of SEA0400 on Arrhythmogenicity in a Langendorff-Perfused 1-Month Myocardial Infarction Rabbit Model.
Pacing and clinical electrophysiology : PACE 2013;36(5):596-606.
2013: Yukio Ago; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Atsuko Hayata-Takano; Keisuke Hazama; Naoki Hiramatsu; Toshihiro Ishihama; Toshiyuki Kawasaki; Atsuro Nakazato; Hirotaka Onoe; Yasuhiro Shibasaki; Norihito Shintani; Kazuhiro Takuma; Toshio Matsuda
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide.
Behavioural pharmacology 2013;24(1):74-7.
2013: Yukio Ago; Ryota Araki; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Naoki Hiramatsu; Toshiyuki Kawasaki; Yuki Kita; Atsuro Nakazato; Hirotaka Onoe; Kazuhiro Takuma; Koji Yano; Toshio Matsuda
Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice.
Neuropharmacology 2013;65():29-38.
2013: Hiroaki Inoue; Yusuke Sakurai; Norihito Shintani; Akemichi Baba; Atsuko Hayata-Takano; Shintaro Higashi; Hitoshi Hashimoto
PACAP Inhibits β-cell Mass Expansion in a Mouse Model of Type II Diabetes: Persistent Suppressive Effects on Islet Density.
Frontiers in endocrinology 2013;4():27.
2012: Nobutaka Morimoto; Hiroko Namimatsu; Masamitsu Shimazawa; Junji Takeda; Kazuhiro Tsuruma; Akemichi Baba; Nobuaki Egashira; Michihiro Fujiwara; Yusuke Gotoh; Kazuhide Hayakawa; Ichiro Horie; Kyoji Horie; Takahiro Iwamoto; Katsunori Iwasaki; Takuya Iyoda; Satomi Kita; Issei Komuro; Toshio Matsuda; Kenichi Mishima; Hideaki Hara
Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice.
Biochemical and biophysical research communications 2012;429(3-4):186-90.
2012: Minako Tajiri; Akemichi Baba; Atsuko Hayata-Takano; Keisuke Hazama; Katsuya Ogata; Kaoru Seiriki; Norihito Shintani; Hitoshi Hashimoto
Serotonin 5-HT(7) receptor blockade reverses behavioral abnormalities in PACAP-deficient mice and receptor activation promotes neurite extension in primary embryonic hippocampal neurons: therapeutic implications for psychiatric disorders.
Journal of molecular neuroscience : MN 2012;48(3):473-81.
2012: Yusuke Sakurai; Norihito Shintani; Atsuko Hayata-Takano; Hiroaki Inoue; Akihiro Arimori; Akemichi Baba; Ken-ichi Hamagami; Hitoshi Hashimoto
Compensatory recovery of blood glucose levels in KKA(y) mice fed a high-fat diet: insulin-sparing effects of PACAP overexpression in β cells.
Journal of molecular neuroscience : MN 2012;48(3):647-53.
2012: Ya Chen; Songping Huang; Toshio Matsuda; Kevin Payne; Vindya S Perara; Akemichi Baba; Xin Yu
Inhibition of the sodium-calcium exchanger via SEA0400 altered manganese-induced T1 changes in isolated perfused rat hearts.
NMR in biomedicine 2012;25(11):1280-5.
2012: Xiaoping Wan; Zhen Song; Akemichi Baba; Michael Cutler; Alain Karma; Toshio Matsuda; David S Rosenbaum
New experimental evidence for mechanism of arrhythmogenic membrane potential alternans based on balance of electrogenic I(NCX)/I(Ca) currents.
Heart rhythm : the official journal of the Heart Rhythm Society 2012;9(10):1698-705.
2012: Toshiyuki Kawasaki; Toshiyuki Marumo; Toshio Matsuda; Tomoko Mori; Atsuro Nakazato; Yukio Ago; Akemichi Baba; Shigeyuki Chaki; Hisashi Doi; Hitoshi Hashimoto; Keiko Shirakami; Masaaki Suzuki; Yasuyoshi Watanabe; Hirotaka Onoe
Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(9):1737-46.
2012: Takeshi Shimada; Kikuko Shinohara; Norihito Shintani; Yoshihiro Takai; Akihiro Toi; Keiko Tominaga-Yoshino; Atsushi Yamasaki; Kouji Asano; Akemichi Baba; Atsuko Hayata-Takano; Akihiko Ogura; Hitoshi Hashimoto
A simplified method to generate serotonergic neurons from mouse embryonic stem and induced pluripotent stem cells.
Journal of neurochemistry 2012;122(1):81-93.
2012: Daisuke Kamimura; Yutaka Komiyama; Issei Komuro; Toshiaki Mano; Toshio Matsuda; Takeshi Miwa; Tomohito Ohtani; Yosuke Omori; Yasushi Sakata; Hakuo Takahashi; Yasuharu Takeda; Shunsuke Tamaki; Yasumasa Tsukamoto; Satoshi Umemura; Akemichi Baba; Kazuharu Furutani; Masamichi Yoshika; Kazuhiro Yamamoto
Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction.
European heart journal 2012;33(11):1408-16.
2012: Andrea Tamas; N Shintani; Krisztina Szabadfi; Tamás Atlasz; Akemichi Baba; B Fulop; R Gabriel; H Hashimoto; Zsuzsanna Helyes; Péter Kiss; A Nemeth; Dóra Reglodi
Comparative examination of inner ear in wild type and pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice.
Neurotoxicity research 2012;21(4):435-44.
2012: Zhenghang Zhao; Charelle Allen; Akemichi Baba; Nadezhda Fefelova; Toshio Matsuda; Hairuo Wen; Lai-Hua Xie
Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents?
American journal of physiology. Heart and circulatory physiology 2012;302(8):H1636-44.
2012: Fushun Wang; Qiwu Xu; Nathan A Smith; Takahiro Takano; Akemichi Baba; Lane Bekar; Takumi Fujita; Toshio Matsuda; Maiken Nedergaard
Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.
Science signaling 2012;5(218):ra26.
2012: Peter Milberg; Frank U Müller; Sigrid Nikol; Dennis Noble; Nani Osada; Christian Pott; Trong Hung Quang; Matthias Ruhe; Jörg Stypmann; Martin Fink; Gerrit Frommeyer; Rainer Klocke; Toshio Matsuda; Akemichi Baba; Günter Breithardt; Lars Eckardt
Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure.
Heart rhythm : the official journal of the Heart Rhythm Society 2012;9(4):570-8.
2012: Ryota Haba; Akemichi Baba; Atsuko Hayata; Yusuke Onaka; Norihito Shintani; Risa Takenaga; Hyper Wang; Hitoshi Hashimoto
Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala.
Behavioural brain research 2012;228(2):423-31.
2012: Satoko Hattori; Akemichi Baba; Hitoshi Hashimoto; Norihito Shintani; Keizo Takao; Koichi Tanda; Keiko Toyama; Tsuyoshi Miyakawa
Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice.
Frontiers in behavioral neuroscience 2012;6():58.
2012: Yukio Ago; Ryota Araki; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Toshiyuki Kawasaki; Atsuro Nakazato; Hirotaka Onoe; Kazuhiro Takuma; Koji Yano; Toshio Matsuda
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses isolation rearing-induced abnormal behaviors in mice.
Journal of pharmacological sciences 2012;118(2):295-8.
2011: Petros Andrikopoulos; Akemichi Baba; Mustafa B A Djamgoz; Toshio Matsuda; Muhammad M Yaqoob; Suzanne A Eccles
Ca2+ influx through reverse mode Na+/Ca2+ exchange is critical for vascular endothelial growth factor-mediated extracellular signal-regulated kinase (ERK) 1/2 activation and angiogenic functions of human endothelial cells.
The Journal of biological chemistry 2011;286(44):37919-31.
2011: Tova Feldmann; David Lichtstein; Toshio Matsuda; Akemichi Baba; Michal Shahar; Haim Rosen
The Na(+)/Ca(2+)-exchanger: an essential component in the mechanism governing cardiac steroid-induced slow Ca(2+) oscillations.
Cell calcium 2011;50(5):424-32.
2011: Yukio Ago; Ryota Araki; Akemichi Baba; Shigeyuki Chaki; Hitoshi Hashimoto; Naoki Hiramatsu; Toshiyuki Kawasaki; Atsuro Nakazato; Hirotaka Onoe; Kazuhiro Takuma; Koji Yano; Toshio Matsuda
Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission.
Psychopharmacology 2011;217(3):443-52.
2011: Tetsuaki Nashida; Teisuke Takahashi; Kazuhiro Takuma; Yukio Ago; Akemichi Baba; Sayoko Fukuda; Toshiyuki Kawasaki; Toshio Matsuda
The specific Na(+)/Ca(2+) exchange inhibitor SEA0400 prevents nitric oxide-induced cytotoxicity in SH-SY5Y cells.
Neurochemistry international 2011;59(1):51-8.
2011: Naohiro Tsukiyama; Hitoshi Hashimoto; Atsuko Hayata; Keisuke Hazama; Michiya Kakuda; Yoshiko Morita; Katsuya Ogata; Yoko Saida; Norihito Shintani; Minako Tajiri; Mamoru Tanida; Akemichi Baba
PACAP centrally mediates emotional stress-induced corticosterone responses in mice.
Stress (Amsterdam, Netherlands) 2011;14(4):368-75.
2011: Peter Szakaly; Eszter Laszlo; Krisztina Kovacs; Boglarka Racz; Gabriella Horvath; Andrea Ferencz; Andrea Lubics; Peter Kiss; Andrea Tamas; Reka Brubel; Balazs Opper; Akemichi Baba; Hitoshi Hashimoto; Jozsef Farkas; Attila Matkovits; Tamás Magyarlaki; Zsuzsanna Helyes; Dóra Reglodi
Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) show increased susceptibility to in vivo renal ischemia/reperfusion injury.
Neuropeptides 2011;45(2):113-21.
2011: Ryota Hashimoto; Yuka Yasuda; Kazutaka Ohi; Motoyuki Fukumoto; Hidenaga Yamamori; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Masatoshi Takeda
[Translational research for mental disorder -schizophrenia].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2011;137(2):79-82.
2011: Toshiyuki Kawasaki; Yukio Ago; Koji Yano; Ryota Araki; Yusuke Washida; Hirotaka Onoe; Shigeyuki Chaki; Atsuro Nakazato; Hitoshi Hashimoto; Akemichi Baba; Kazuhiro Takuma; Toshio Matsuda
Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice.
Neuropharmacology 2011;60(2-3):397-404.
2011: Yukio Ago; M Yoneyama; T Ishihama; S Kataoka; K Kawada; Toshiyuki Tanaka; K Ogita; Norihito Shintani; Hisashi Hashimoto; Akemichi Baba; Kazuhiro Takuma; Toshio Matsuda
Role of endogenous pituitary adenylate cyclase-activating polypeptide in adult hippocampal neurogenesis.
Neuroscience 2011;172():554-61.
2011: Hitoshi Hashimoto; Norihito Shintani; Mamoru Tanida; Atsuko Hayata; Ryota Hashimoto; Akemichi Baba
PACAP is implicated in the stress axes.
Current pharmaceutical design 2011;17(10):985-9.
2011: Benjamin Waghorn; Autumn Schumacher; Jimei Liu; Stephanie Jacobs; Akemichi Baba; Toshio Matsuda; Nathan Eugene Yanasak; Tom Chih-Chuang Hu
Indirectly probing Ca(2+) handling alterations following myocardial infarction in a murine model using T(1)-mapping manganese-enhanced magnetic resonance imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2011;65(1):239-49.
2011: Kimi Endo; Tomoya Nakamachi; T Seki; Nobuyuki Kagami; Yoshihiro Wada; Keisuke Nakamura; Koji Kishimoto; Motohide Hori; Daisuke Tsuchikawa; Norihito Shinntani; Hitoshi Hashimoto; Akemichi Baba; Ryohei Koide; Seiji Shioda
Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse.
Journal of molecular neuroscience : MN 2011;43(1):22-9.
2011: Yusuke Sakurai; Norihito Shintani; Atsuko Hayata; Hitoshi Hashimoto; Akemichi Baba
Trophic effects of PACAP on pancreatic islets: a mini-review.
Journal of molecular neuroscience : MN 2011;43(1):3-7.
2011: Yusuke Sakurai; Norihito Shintani; Akihiro Arimori; Ken-Ichi Hamagami; Naoko Higuchi; Hiroaki Inoue; Kazuya Ikeda; Atsuko Hayata; Hitoshi Hashimoto; Akemichi Baba
Cerulein-induced acute pancreatitis in PACAP knockout mice.
Journal of molecular neuroscience : MN 2011;43(1):8-15.
2010: Douglas B Kintner; Xinzhi Chen; Julia Currie; Vishal Chanana; Peter Ferrazzano; Akemichi Baba; Toshio Matsuda; Mike Cohen; John Orlowski; Shing-Yan Chiu; Jack Taunton; Dandan Sun
Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia.
The Journal of biological chemistry 2010;285(45):35155-68.
2010: Atsushi Kasai; Yuki Ishimaru; Toshihiko Kinjo; Tatsuya Satooka; Nao Matsumoto; Yasuhiro Yoshioka; Akiko Yamamuro; Fumi Gomi; Norihito Shintani; Akemichi Baba; Sadaaki Maeda
Apelin is a crucial factor for hypoxia-induced retinal angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(11):2182-7.
2010: Atsuro Miyata; Seiji Shioda; Akemichi Baba
The 9th International Symposium on VIP, PACAP, and Related Peptides.
Journal of molecular neuroscience : MN 2010;42(3):264-5.
2010: Masanori Nakata; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Toshihiko Yada
Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity.
Journal of molecular neuroscience : MN 2010;42(3):404-10.
2010: Agnes Kemény; Dóra Reglodi; Renáta Cseharovszky; Hitoshi Hashimoto; Akemichi Baba; János Szolcsányi; Erika Pintér; Zsuzsanna Helyes
Pituitary adenylate cyclase-activating polypeptide deficiency enhances oxazolone-induced allergic contact dermatitis in mice.
Journal of molecular neuroscience : MN 2010;42(3):443-9.
2010: Hirokazu Ohtaki; Atsushi Satoh; Tomoya Nakamachi; Sachiko Yofu; Kenji Dohi; Hiroyoshi Mori; Kenji Ohara; Kazuyuki Miyamoto; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba; Masaji Matsunaga; Seiji Shioda
Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor.
Journal of molecular neuroscience : MN 2010;42(3):397-403.
2010: Andrea Ferencz; Péter Kiss; Gyorgy Weber; Zsuzsanna Helyes; Norihito Shintani; Akemichi Baba; Dóra Reglodi
Comparison of intestinal warm ischemic injury in PACAP knockout and wild-type mice.
Journal of molecular neuroscience : MN 2010;42(3):435-42.
2010: Andrea Ferencz; Gyorgy Weber; Zsuzsanna Helyes; Hitoshi Hashimoto; Akemichi Baba; Dóra Reglodi
Presence of endogenous PACAP-38 ameliorated intestinal cold preservation tissue injury.
Journal of molecular neuroscience : MN 2010;42(3):428-34.
2010: Katalin Sándor; V Kormos; B Botz; A Imreh; Kata Bölcskei; Balázs Gaszner; A Markovics; János Szolcsányi; N Shintani; H Hashimoto; Akemichi Baba; Dóra Reglodi; Zsuzsanna Helyes
Impaired nocifensive behaviours and mechanical hyperalgesia, but enhanced thermal allodynia in pituitary adenylate cyclase-activating polypeptide deficient mice.
Neuropeptides 2010;44(5):363-71.
2010: Indri N Purwana; Haruhiko Kanasaki; Aki Oride; Tselmeg Mijiddorj; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Kohji Miyazaki
GnRH-induced PACAP and PAC1 receptor expression in pituitary gonadotrophs: a possible role in the regulation of gonadotropin subunit gene expression.
Peptides 2010;31(9):1748-55.
2010: G Horvath; Boglarka Racz; P Szakaly; Péter Kiss; E Laszlo; L Hau; Andrea Tamas; Zsuzsanna Helyes; Andrea Lubics; H Hashimoto; Akemichi Baba; Dóra Reglodi
Mice deficient in neuropeptide PACAP demonstrate increased sensitivity to in vitro kidney hypoxia.
Transplantation proceedings 2010;42(6):2293-5.
2010: Andrea Ferencz; K Nedvig; T Fekecs; Boglárka Rácz; György Wéber; H Hashimoto; Akemichi Baba; Zsuzsanna Helyes; Dora Reglödi
Comparison of intestinal cold preservation injury on pituitary adenylate cyclase-activating polypeptide in knockout and wild-type mice.
Transplantation proceedings 2010;42(6):2290-2.
2010: Toshihiro Ishihama; Yukio Ago; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Kazuhiro Takuma; Toshio Matsuda
Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice.
Behavioural brain research 2010;209(2):274-80.
2010: Hiroyoshi Mori; Tomoya Nakamachi; Hirokazu Ohtaki; Sachiko Yofu; Atsushi Sato; Kimi Endo; Yoshitaka Iso; Hiroshi Suzuki; Youichi Takeyama; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Seiji Shioda
Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on Doxorubicin-induced cardiomyopathy in mice.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(6):1183-90.
2010: Mamoru Tanida; Norihito Shintani; Yoshiko Morita; Naohiro Tsukiyama; Michiyoshi Hatanaka; Hitoshi Hashimoto; Hajime Sawai; Akemichi Baba; Katsuya Nagai
Regulation of autonomic nerve activities by central pituitary adenylate cyclase-activating polypeptide.
Regulatory peptides 2010;161(1-3):73-80.
2010: Maki Tsumura; Reijiro Okumura; Shoko Tatsuyama; Hideki Ichikawa; Takashi Muramatsu; Toshio Matsuda; Akemichi Baba; Keiko Suzuki; Hiroshi Kajiya; Yoshinori Sahara; Masayuki Tokuda; Yasunori Momose; Masakazu Tazaki; Masaki Shimono; Yoshiyuki Shibukawa
Ca2+ extrusion via Na+-Ca2+ exchangers in rat odontoblasts.
Journal of endodontics 2010;36(4):668-74.
2010: Gabriella Horvath; Laszlo Mark; Reka Brubel; Peter Szakaly; Boglarka Racz; Péter Kiss; Andrea Tamas; Zsuzsanna Helyes; Andrea Lubics; Hitoshi Hashimoto; Akemichi Baba; Norihito Shintani; Gergely Furjes; Jozsef Nemeth; Dóra Reglodi
Mice deficient in pituitary adenylate cyclase activating polypeptide display increased sensitivity to renal oxidative stress in vitro.
Neuroscience letters 2010;469(1):70-4.
2010: Ryota Hashimoto; Hitoshi Hashimoto; Norihito Shintani; Kazutaka Ohi; Hiroaki Hori; Osamu Saitoh; Asako Kosuga; Masahiko Tatsumi; Nakao Iwata; Norio Ozaki; Kunitoshi Kamijima; Akemichi Baba; Masatoshi Takeda; Hiroshi Kunugi
Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder.
Neuroscience letters 2010;468(3):300-2.
2010: Michiyoshi Hatanaka; Norihiro Shibata; Norihito Shintani; Ryota Haba; Atsuko Hayata; Hitoshi Hashimoto; Akemichi Baba
15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells.
Journal of pharmacological sciences 2010;113(1):89-93.
2010: Chihiro Kawaguchi; Yasushi Isojima; Norihito Shintani; Michiyoshi Hatanaka; Xiaohong Guo; Nobuaki Okumura; Katsuya Nagai; Hitoshi Hashimoto; Akemichi Baba
PACAP-deficient mice exhibit light parameter-dependent abnormalities on nonvisual photoreception and early activity onset.
PloS one 2010;5(2):e9286.
2010: Kohei Yamada; Shinsuke Matsuzaki; Tsuyoshi Hattori; Ryusuke Kuwahara; Manabu Taniguchi; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba; Natsuko Kumamoto; Kazuo Yamada; Takeo Yoshikawa; Taiichi Katayama; Masaya Tohyama
Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizations.
PloS one 2010;5(1):e8596.
2010: Kazuhiro Tanaka; Akiko Kunishige-Yamamoto; Hitoshi Hashimoto; Norihito Shintani; Atsuko Hayata; Akemichi Baba
Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice.
Biochemical and biophysical research communications 2010;391(1):773-7.
2010: Xinzhi Chen; Douglas B Kintner; Akemichi Baba; Toshio Matsuda; Gary E Shull; Dandan Sun
Protein aggregation in neurons following OGD: a role for Na+ and Ca2+ ionic dysregulation.
Journal of neurochemistry 2010;112(1):173-82.
2010: Tomoya Nakamachi; Hirokazu Ohtaki; Sachiko Yofu; Kenji Dohi; Jun Watanabe; Hiroyoshi Mori; Atsushi Sato; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba; Seiji Shioda
Endogenous pituitary adenylate cyclase activating polypeptide is involved in suppression of edema in the ischemic brain.
Acta neurochirurgica. Supplement 2010;106():43-6.
2009: Ryo Saito; Erina Kaneko; Yusuke Tanaka; Kenji Honda; Toshio Matsuda; Akemichi Baba; Issei Komuro; Satomi Kita; Takahiro Iwamoto; Yukio Takano
Involvement of Na+/Ca2+ exchanger in pentylenetetrazol-induced convulsion by use of Na+/Ca2+ exchanger knockout mice.
Biological & pharmaceutical bulletin 2009;32(11):1928-30.
2009: Ben Waghorn; Yuhui Yang; Akemichi Baba; Toshio Matsuda; Autumn Schumacher; Nathan Eugene Yanasak; Tom Chih-Chuang Hu
Assessing manganese efflux using SEA0400 and cardiac T1-mapping manganese-enhanced MRI in a murine model.
NMR in biomedicine 2009;22(8):874-81.
2009: Ken-ichi Hamagami; Yusuke Sakurai; Norihito Shintani; Naoko Higuchi; Kazuya Ikeda; Hitoshi Hashimoto; Akinobu Suzuki; Hiroshi Kiyama; Akemichi Baba
Over-expression of pancreatic pituitary adenylate cyclase-activating polypeptide (PACAP) aggravates cerulein-induced acute pancreatitis in mice.
Journal of pharmacological sciences 2009;110(4):451-8.
2009: Heon Yung Gee; Young Woong Kim; Min Jae Jo; Wan Namkung; Joo Young Kim; Hyun Woo Park; Kyung Sik Kim; Hoguen Kim; Akemichi Baba; Jinhee Yang; Eunjoon Kim; Kyung Hwan Kim; Min Goo Lee
Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells.
Gastroenterology 2009;137(2):607-17, 617.e1-4.
2009: Hitoshi Hashimoto; Ryota Hashimoto; Norihito Shintani; Kazuhiro Tanaka; Akiko Yamamoto; Michiyoshi Hatanaka; Xiaohong Guo; Yoshiko Morita; Mamoru Tanida; Katsuya Nagai; Masatoshi Takeda; Akemichi Baba
Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone.
Journal of neurochemistry 2009;110(2):595-602.
2009: Toshihide Kashihara; Koichi Nakayama; Toshio Matsuda; Akemichi Baba; Tomohisa Ishikawa
Role of Na+/Ca2+ exchanger-mediated Ca2+ entry in pressure-induced myogenic constriction in rat posterior cerebral arteries.
Journal of pharmacological sciences 2009;110(2):218-22.
2009: Rie Tsuchida; Masahiro Kubo; Norihito Shintani; Michikazu Abe; Katalin Köves; Kazuki Uetsuki; Mariko Kuroda; Hitoshi Hashimoto; Akemichi Baba
Inhibitory effects of osemozotan, a serotonin 1A-receptor agonist, on methamphetamine-induced c-Fos expression in prefrontal cortical neurons.
Biological & pharmaceutical bulletin 2009;32(4):728-31.
2009: Rie Tsuchida; Masahiro Kubo; Mariko Kuroda; Yasuhiro Shibasaki; Norihito Shintani; Michikazu Abe; Katalin Köves; Hitoshi Hashimoto; Akemichi Baba
An antihyperkinetic action by the serotonin 1A-receptor agonist osemozotan co-administered with psychostimulants or the non-stimulant atomoxetine in mice.
Journal of pharmacological sciences 2009;109(3):396-402.
2008: Sigolène Larivière; Ghislaine Garrel-Lazayres; Violaine Simon; Norihito Shintani; Akemichi Baba; Raymond Counis; Joëlle Cohen-Tannoudji
Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3',5'-cyclic adenosine-5'-monophosphate pathway in LbetaT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor.
Endocrinology 2008;149(12):6389-98.
2008: Michiyoshi Hatanaka; Mamoru Tanida; Norihito Shintani; Yasushi Isojima; Chihiro Kawaguchi; Hitoshi Hashimoto; Michiya Kakuda; Ryota Haba; Katsuya Nagai; Akemichi Baba
Lack of light-induced elevation of renal sympathetic nerve activity and plasma corticosterone levels in PACAP-deficient mice.
Neuroscience letters 2008;444(2):153-6.
2008: Peter Milberg; Christian Pott; Martin Fink; Gerrit Frommeyer; Toshio Matsuda; Akemichi Baba; Nani Osada; Günter Breithardt; Denis Noble; Lars Eckardt
Inhibition of the Na+/Ca2+ exchanger suppresses torsades de pointes in an intact heart model of long QT syndrome-2 and long QT syndrome-3.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(10):1444-52.
2008: Atsushi Kasai; Norihito Shintani; Hideaki Kato; Satoshi Matsuda; Fumi Gomi; Ryota Haba; Hitoshi Hashimoto; Michiya Kakuda; Yasuo Tano; Akemichi Baba
Retardation of retinal vascular development in apelin-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1717-22.
2008: Kiyomi Hagi; Yasu-Taka Azuma; Hidemitsu Nakajima; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Tadayoshi Takeuchi
Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus.
European journal of pharmacology 2008;590(1-3):80-6.
2008: Xinzhi Chen; Douglas B Kintner; Jing Luo; Akemichi Baba; Toshio Matsuda; Dandan Sun
Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: role of Na+-K+-Cl- cotransporter.
Journal of neurochemistry 2008;106(4):1563-76.
2008: Yasu-Taka Azuma; Kiyomi Hagi; Norihito Shintani; Mitsuru Kuwamura; Hidemitsu Nakajima; Hitoshi Hashimoto; Akemichi Baba; Tadayoshi Takeuchi
PACAP provides colonic protection against dextran sodium sulfate induced colitis.
Journal of cellular physiology 2008;216(1):111-9.
2008: Shuhei Tomimoto; Tatsuya Ojika; Norihito Shintani; Hitoshi Hashimoto; Ken-Ichi Hamagami; Kazuya Ikeda; Masanori Nakata; Toshihiko Yada; Yusuke Sakurai; Takeshi Shimada; Yoshiko Morita; Chie Ishida; Akemichi Baba
Markedly reduced white adipose tissue and increased insulin sensitivity in adcyap1-deficient mice.
Journal of pharmacological sciences 2008;107(1):41-8.
2008: Andrea Heinzlmann; Eszter Kirilly; Kinga Meltzer; Enikö Szabó; Akemichi Baba; Hitoshi Hashimoto; Katalin Köves
PACAP is transiently expressed in anterior pituitary gland of rats: in situ hybridization and cell immunoblot assay studies.
Peptides 2008;29(4):571-7.
2008: Ken Koda; Yukio Ago; Toshiyuki Kawasaki; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice.
Psychopharmacology 2008;196(2):293-301.
2008: Yukio Ago; Shigeo Nakamura; Akemichi Baba; Toshio Matsuda
Neuropsychotoxicity of abused drugs: effects of serotonin receptor ligands on methamphetamine- and cocaine-induced behavioral sensitization in mice.
Journal of pharmacological sciences 2008;106(1):15-21.
2007: Ryota Hashimoto; Hitoshi Hashimoto; Norihito Shintani; Sachie Chiba; S Hattori; Takeya Okada; M Nakajima; Kazuhiro Tanaka; Naofumi Kawagishi; Kiyotaka Nemoto; Takeyuki Mori; Takashi Ohnishi; Hiroko Noguchi; Hiroaki Hori; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; T Nakabayashi; O Saitoh; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; Daniel R Weinberger; Hiroshi Kunugi; Akemichi Baba
Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia.
Molecular psychiatry 2007;12(11):1026-32.
2007: Akemichi Baba
[Molecular pharmacologic approaches to functional analysis of new biological target molecules for drug discovery].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(10):1643-54.
2007: Toshiyuki Kawasaki; Tatsuya Kitao; Katsuhiro Nakagawa; Hiroko Fujisaki; Yoshimi Takegawa; Ken Koda; Yukio Ago; Akemichi Baba; Toshio Matsuda
Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger.
Glia 2007;55(13):1325-33.
2007: Chihiro Kawaguchi; Yasushi Isojima; Akemichi Baba
[Circadian rhythm monitoring in an individual animal].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2007;130(3):193-9.
2007: Harumi Fujii; Toshihiro Ishihama; Yukio Ago; Norihito Shintani; Michiya Kakuda; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Methamphetamine-induced hyperactivity and behavioral sensitization in PACAP deficient mice.
Peptides 2007;28(9):1674-9.
2007: Yukio Ago; Shigeo Nakamura; Naoko Kajita; Misato Uda; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Ritanserin reverses repeated methamphetamine-induced behavioral and neurochemical sensitization in mice.
Synapse (New York, N.Y.) 2007;61(9):757-63.
2007: Hai Chen; Douglas B Kintner; Mathew Jones; Toshio Matsuda; Akemichi Baba; Lech Kiedrowski; Dandan Sun
AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger.
Journal of neurochemistry 2007;102(6):1783-95.
2007: Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Production of monocyte chemoattractant protein-1 and cytokine-induced neutrophil chemoattractant-1 in rat brain is stimulated by intracerebroventricular administration of an endothelin ETB receptor agonist.
Neuroreport 2007;18(12):1275-9.
2007: Toshiyuki Kawasaki; Kotaro Ishihara; Yukio Ago; Akemichi Baba; Toshio Matsuda
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.
The Journal of pharmacology and experimental therapeutics 2007;322(1):274-81.
2007: Yukio Ago; Keiko Takahashi; Shigeo Nakamura; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test.
Journal of pharmacological sciences 2007;104(2):153-8.
2007: Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba
[Neuropeptide PACAP and neuropsychological function: unexpected insights from mouse mutants].
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(4):375-9.
2007: Yuko Takayasu; Junko Nakaki; Toshiyuki Kawasaki; Ken Koda; Yukio Ago; Akemichi Baba; Toshio Matsuda
Edaravone, a radical scavenger, inhibits mitochondrial permeability transition pore in rat brain.
Journal of pharmacological sciences 2007;103(4):434-7.
2007: T Hattori; Kousuke Baba; S Matsuzaki; Akiko Honda; K Miyoshi; K Inoue; Manabu Taniguchi; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba; S Shimizu; F Yukioka; N Kumamoto; A Yamaguchi; Masaya Tohyama; Taiichi Katayama
A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.
Molecular psychiatry 2007;12(4):398-407.
2007: Maiko Sato; Yukio Ago; Ken Koda; Shigeo Nakamura; Toshiyuki Kawasaki; Akemichi Baba; Toshio Matsuda
Role of postsynaptic serotonin1A receptors in risperidone-induced increase in acetylcholine release in rat prefrontal cortex.
European journal of pharmacology 2007;559(2-3):155-60.
2007: Norihito Shintani; Kiyokazu Ogita; Hitoshi Hashimoto; Akemichi Baba
Recent studies on the trimethyltin actions in central nervous systems.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(3):451-61.
2006: Yukio Ago; Maiko Sato; Shigeo Nakamura; Akemichi Baba; Toshio Matsuda
Lack of enhanced effect of antipsychotics combined with fluvoxamine on acetylcholine release in rat prefrontal cortex.
Journal of pharmacological sciences 2006;102(4):419-22.
2006: Shigeo Nakamura; Yukio Ago; Aiko Hayashi; Soichi Itoh; Michiya Kakuda; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Modification of cocaine-induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice.
Synapse (New York, N.Y.) 2006;60(7):479-84.
2006: Toshiya Harasawa; Yukio Ago; Soichi Itoh; Akemichi Baba; Toshio Matsuda
Role of serotonin type 1A receptors in fluvoxamine-induced inhibition of marble-burying behavior in mice.
Behavioural pharmacology 2006;17(7):637-40.
2006: Hiroshi Kunugi; Ryota Hashimoto; Takeya Okada; Hiroaki Hori; Tetsuo Nakabayashi; Akemichi Baba; K Kudo; M Omori; S Takahashi; Ryoutaro Tsukue; Kimitaka Anami; Naotugu Hirabayashi; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; T Asada; Seiichi Harada; Kunimasa Arima; Osamu Saitoh
Possible association between nonsynonymous polymorphisms of the anaplastic lymphoma kinase (ALK) gene and schizophrenia in a Japanese population.
Journal of neural transmission (Vienna, Austria : 1996) 2006;113(10):1569-73.
2006: Yutaka Koyama; Masafumi Kiyo-oka; Masakazu Osakada; Naotaka Horiguchi; Norihito Shintani; Yukio Ago; Michiya Kakuda; Akemichi Baba; Toshio Matsuda
Expression of prokineticin receptors in mouse cultured astrocytes and involvement in cell proliferation.
Brain research 2006;1112(1):65-9.
2006: Yukio Ago; Shigeo Nakamura; Aiko Hayashi; Soichi Itoh; Akemichi Baba; Toshio Matsuda
Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice.
Pharmacology, biochemistry, and behavior 2006;85(1):198-205.
2006: Toshio Matsuda; Takayuki Nagano; Motohiko Takemura; Akemichi Baba
Topics on the Na+/Ca2+ exchanger: responses of Na+/Ca2+ exchanger to interferon-gamma and nitric oxide in cultured microglia.
Journal of pharmacological sciences 2006;102(1):22-6.
2006: Yukio Ago; Shigeo Nakamura; Misato Uda; YASUSHI KAJII; Michikazu Abe; Akemichi Baba; Toshio Matsuda
Attenuation by the 5-HT1A receptor agonist osemozotan of the behavioral effects of single and repeated methamphetamine in mice.
Neuropharmacology 2006;51(4):914-22.
2006: Toshiyuki Kawasaki; Kotaro Ishihara; Yukio Ago; Shigeo Nakamura; Soichi Itoh; Akemichi Baba; Toshio Matsuda
Protective effect of the radical scavenger edaravone against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum.
European journal of pharmacology 2006;542(1-3):92-9.
2006: R Arthur Bouwman; Kanita Salic; F Gieneke Padding; Etto C Eringa; Brechje J van Beek-Harmsen; Toshio Matsuda; Akemichi Baba; René J P Musters; Walter J Paulus; Jaap J de Lange; Christa Boer
Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger.
Circulation 2006;114(1 Suppl):I226-32.
2006: Norihito Shintani; Hitoshi Hashimoto; Kazuhiro Tanaka; Naofumi Kawagishi; Chihiro Kawaguchi; Michiyoshi Hatanaka; Yukio Ago; Toshio Matsuda; Akemichi Baba
Serotonergic inhibition of intense jumping behavior in mice lacking PACAP (Adcyap1-/-).
Annals of the New York Academy of Sciences 2006;1070():545-9.
2006: Yoshiko Morita; Daisuke Yanagida; Norihito Shintani; Kiyokazu Ogita; Norito Nishiyama; Rie Tsuchida; Hitoshi Hashimoto; Akemichi Baba
Lack of trimethyltin (TMT)-induced elevation of plasma corticosterone in PACAP-deficient mice.
Annals of the New York Academy of Sciences 2006;1070():450-6.
2006: Megumi Hirose; Hitoshi Hashimoto; Junko Iga; Norihito Shintani; Megumi Nakanishi; Naohisa Arakawa; Takeshi Shimada; Akemichi Baba
Inhibition of self-renewal and induction of neural differentiation by PACAP in neural progenitor cells.
Annals of the New York Academy of Sciences 2006;1070():342-7.
2006: Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba
New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice.
Annals of the New York Academy of Sciences 2006;1070():75-89.
2006: Kazuhiro Tanaka; Norihito Shintani; Hitoshi Hashimoto; Naofumi Kawagishi; Yukio Ago; Toshio Matsuda; Ryota Hashimoto; Hiroshi Kunugi; Akiko Yamamoto; Chihiro Kawaguchi; Takeshi Shimada; Akemichi Baba
Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyap1-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(19):5091-7.
2006: Hirokazu Ohtaki; Tomoya Nakamachi; Kenji Dohi; Yoichi Aizawa; Atsushi Takaki; Kei Hodoyama; Sachiko Yofu; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba; Manfred Kopf; Yoichiro Iwakura; Kouhei Matsuda; Akira Arimura; Seiji Shioda
Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(19):7488-93.
2006: Kazunori Mukai; Tadayoshi Takeuchi; Makiko Toyoshima; Yuji Satoh; Akikazu Fujita; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Fumiaki Hata
PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: findings obtained in PACAP knockout mice.
Regulatory peptides 2006;133(1-3):54-61.
2006: Makiko Toyoshima; Tadayoshi Takeuchi; Hiroto Goto; Kazunori Mukai; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Fumiaki Hata
Roles of PACAP and PHI as inhibitory neurotransmitters in the circular muscle of mouse antrum.
Pflügers Archiv : European journal of physiology 2006;451(4):559-68.
2006: Tetsuo Fukushima; Masahiro Koide; Yukio Ago; Akemichi Baba; Toshio Matsuda
T-817MA, a novel neurotrophic agent, improves sodium nitroprusside-induced mitochondrial dysfunction in cortical neurons.
Neurochemistry international 2006;48(2):124-30.
2005: Shigeo Nakamura; Yukio Ago; Soichi Itoh; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Effect of zotepine on dopamine, serotonin and noradrenaline release in rat prefrontal cortex.
European journal of pharmacology 2005;528(1-3):95-8.
2005: Yukio Ago; Toshiya Harasawa; Soichi Itoh; Shigeo Nakamura; Akemichi Baba; Toshio Matsuda
Antidepressant-like effect of coadministration of sulpiride and fluvoxamine in mice.
European journal of pharmacology 2005;520(1-3):86-90.
2005: Yutaka Koyama; Kimiko Tsujikawa; Toshio Matsuda; Akemichi Baba
Endothelin increases expression of exon III- and exon IV-containing brain-derived neurotrophic factor transcripts in cultured astrocytes and rat brain.
Journal of neuroscience research 2005;80(6):809-16.
2005: Norihito Shintani; Sayoko Suetake; Hitoshi Hashimoto; Kazumi Koga; Atsushi Kasai; Chihiro Kawaguchi; Yoshiko Morita; Megumi Hirose; Yoshiyuki Sakai; Shuhei Tomimoto; Toshio Matsuda; Akemichi Baba
Neuroprotective action of endogenous PACAP in cultured rat cortical neurons.
Regulatory peptides 2005;126(1-2):123-8.
2005: Megumi Hirose; Hitoshi Hashimoto; Norihito Shintani; Megumi Nakanishi; Naohisa Arakawa; Junko Iga; Hitoshi Niwa; Jun-Ichi Miyazaki; Akemichi Baba
Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells.
Regulatory peptides 2005;126(1-2):109-13.
2005: Tetsuo Ogawa; Tomoya Nakamachi; Hirokazu Ohtaki; Hitoshi Hashimoto; Shintani N; Akemichi Baba; Jun Watanabe; Sakae Kikuyama; Seiji Shioda
Monoaminergic neuronal development is not affected in PACAP-gene-deficient mice.
Regulatory peptides 2005;126(1-2):103-8.
2005: Toshio Matsuda; Yutaka Koyama; Akemichi Baba
Functional proteins involved in regulation of intracellular Ca(2+) for drug development: pharmacology of SEA0400, a specific inhibitor of the Na(+)-Ca(2+) exchanger.
Journal of pharmacological sciences 2005;97(3):339-43.
2005: Takayuki Nagano; Masakazu Osakada; Yukio Ago; Yutaka Koyama; Akemichi Baba; Sadaaki Maeda; Motohiko Takemura; Toshio Matsuda
SEA0400, a specific inhibitor of the Na+-Ca2+ exchanger, attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia.
British journal of pharmacology 2005;144(5):669-79.
2005: Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Endothelins stimulate the expression of neurotrophin-3 in rat brain and rat cultured astrocytes.
Neuroscience 2005;136(2):425-33.
2005: Yukio Ago; Shigeo Nakamura; Akemichi Baba; Toshio Matsuda
Sulpiride in combination with fluvoxamine increases in vivo dopamine release selectively in rat prefrontal cortex.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(1):43-51.
2004: Norihito Shintani; Hitoshi Hashimoto; Kazuhiro Tanaka; Chihiro Kawaguchi; Shuhei Tomimoto; Akemichi Baba
Overexpression of PACAP in the pancreas failed to rescue early postnatal mortality in PACAP-null mice.
Regulatory peptides 2004;123(1-3):155-9.
2004: Kazuhiro Tanaka; Hitoshi Hashimoto; Norihito Shintani; Akiko Yamamoto; Akemichi Baba
Reduced hypothermic and hypnotic responses to ethanol in PACAP-deficient mice.
Regulatory peptides 2004;123(1-3):95-8.
2004: Atsushi Kasai; Norihito Shintani; Maki Oda; Michiya Kakuda; Hitoshi Hashimoto; Toshio Matsuda; Shuji Hinuma; Akemichi Baba
Apelin is a novel angiogenic factor in retinal endothelial cells.
Biochemical and biophysical research communications 2004;325(2):395-400.
2004: Xianmin Luo; Akemichi Baba; Toshio Matsuda; Carmelo Romano
Susceptibilities to and mechanisms of excitotoxic cell death of adult mouse inner retinal neurons in dissociated culture.
Investigative ophthalmology & visual science 2004;45(12):4576-82.
2004: Teisuke Takahashi; Kenzo Takahashi; michihito onishi; Taizo Suzuki; Yu Tanaka; Tomomi Ota; Shigeru Yoshida; Shiro Nakaike; Toshio Matsuda; Akemichi Baba
Effects of SEA0400, a novel inhibitor of the Na+/Ca2+ exchanger, on myocardial stunning in anesthetized dogs.
European journal of pharmacology 2004;505(1-3):163-8.
2004: Masanori Nakata; Daisuke Kohno; Norihito Shintani; Yuriko Nemoto; Hitoshi Hashimoto; Akemichi Baba; Toshihiko Yada
PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus.
Neuroscience letters 2004;370(2-3):252-6.
2004: Candace Lee; Neeraj S Visen; Naranjan S Dhalla; Hoa Dinh Le; Michael Isaac; Platon Choptiany; Gil Gross; Alexander Omelchenko; Toshio Matsuda; Akemichi Baba; Kenzo Takahashi; Mark Hnatowich; Larry V Hryshko
Inhibitory profile of SEA0400 [2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] assessed on the cardiac Na+-Ca2+ exchanger, NCX1.1.
The Journal of pharmacology and experimental therapeutics 2004;311(2):748-57.
2004: Tamaki Mabuchi; Norihito Shintani; Shinji Matsumura; Emiko Okuda-Ashitaka; Hitoshi Hashimoto; Tadatoshi Muratani; Toshiaki Minami; Akemichi Baba; Seiji Ito
Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(33):7283-91.
2004: Yutaka Koyama; Yasuhiro Yoshioka; Michiyo Shinde; Toshio Matsuda; Akemichi Baba
Focal adhesion kinase mediates endothelin-induced cyclin D3 expression in rat cultured astrocytes.
Journal of neurochemistry 2004;90(4):904-12.
2004: Takayuki Nagano; Yasushi Kawasaki; Akemichi Baba; Motohiko Takemura; Toshio Matsuda
Up-regulation of Na(+)-Ca2+ exchange activity by interferon-gamma in cultured rat microglia.
Journal of neurochemistry 2004;90(4):784-91.
2004: Yutaka Koyama; Hiroaki Egawa; Masakazu Osakada; Akemichi Baba; Toshio Matsuda
Increase by FK960, a novel cognitive enhancer, in glial cell line-derived neurotrophic factor production in cultured rat astrocytes.
Biochemical pharmacology 2004;68(2):275-82.
2004: Patamawan Phuagphong; Tetsuo Fukushima; Rie Hatanaka; Kazuhiro Tanaka; Akemichi Baba; Toshio Matsuda
T-588, a cognitive enhancer, protects against sodium nitroprusside-induced toxicity in cultured astrocytes.
Journal of pharmacological sciences 2004;95(1):135-8.
2004: Shuhei Tomimoto; Hitoshi Hashimoto; Norihito Shintani; Kyohei Yamamoto; Yuki Kawabata; Ken-Ichi Hamagami; Kazuya Yamagata; Jun-ichiro Miyagawa; Akemichi Baba
Overexpression of pituitary adenylate cyclase-activating polypeptide in islets inhibits hyperinsulinemia and islet hyperplasia in agouti yellow mice.
The Journal of pharmacology and experimental therapeutics 2004;309(2):796-803.
2004: Yutaka Koyama; Shigeo Matsui; Soichi Itoh; Masakazu Osakada; Akemichi Baba; Toshio Matsuda
The selective Na+-Ca2+ exchange inhibitor attenuates brain edema after radiofrequency lesion in rats.
European journal of pharmacology 2004;489(3):193-6.
2004: Yoshiyuki Sakai; Hitoshi Hashimoto; Norihito Shintani; Hironori Katoh; Manabu Negishi; Chihiro Kawaguchi; Atsushi Kasai; Akemichi Baba
PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells.
Brain research. Molecular brain research 2004;123(1-2):18-26.
2004: Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba
[Altered higher brain function in PACAP-knockout mice].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2004;123(4):274-80.
2004: Shuhei Tomimoto; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba
[Transgenic mice overexpressing PACAP in pancreatic beta-cells: acute and chronic effects on insulin and glucose homeostasis].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2004;123(4):261-6.
2004: Kathleen Freson; Hitoshi Hashimoto; Chantal Thys; Christine Wittevrongel; Sophie Danloy; Yoshiko Morita; Norihito Shintani; Yoshiaki Tomiyama; Jos Vermylen; Marc F Hoylaerts; Akemichi Baba; Chris Van Geet
The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation.
The Journal of clinical investigation 2004;113(6):905-12.
2004: Ron Bouchard; Alexander Omelchenko; Hoa Dinh Le; Platon Choptiany; Toshio Matsuda; Akemichi Baba; Kenzo Takahashi; Debora A Nicoll; Kenneth D Philipson; Mark Hnatowich; Larry V Hryshko
Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation.
Molecular pharmacology 2004;65(3):802-10.
2004: Takahiro Iwamoto; Satomi Kita; Akira Uehara; Issei Imanaga; Toshio Matsuda; Akemichi Baba; Takeshi Katsuragi
Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.
The Journal of biological chemistry 2004;279(9):7544-53.
2004: Kazuhiro Takuma; Akemichi Baba; Toshio Matsuda
Astrocyte apoptosis: implications for neuroprotection.
Progress in neurobiology 2004;72(2):111-27.
2003: Norihito Shintani; Shuhei Tomimoto; Hitoshi Hashimoto; Chihiro Kawaguchi; Akemichi Baba
Functional roles of the neuropeptide PACAP in brain and pancreas.
Life sciences 2003;74(2-3):337-43.
2003: Viktoria Vereczki; Katalin Köves; Zsuzsanna E Tóth; Akemichi Baba; Hitoshi Hashimoto; Kristóf Fógel; Akira Arimura; Mária Kausz
Pituitary adenylate cyclase-activating polypeptide does not colocalize with vasoactive intestinal polypeptide in the hypothalamic magnocellular nuclei and posterior pituitary of cats and rats.
Endocrine 2003;22(3):225-37.
2003: Akiko Yamamuro; Yukio Ago; Kazuhiro Takuma; Sadaaki Maeda; Yoshiyuki Sakai; Akemichi Baba; Toshio Matsuda
Possible involvement of astrocytes in neuroprotection by the cognitive enhancer T-588.
Neurochemical research 2003;28(12):1779-83.
2003: Yukio Ago; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex.
Neuropharmacology 2003;45(8):1050-6.
2003: Shogo Matsuyama; Akira Matsumoto; Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba
Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice.
Neuroreport 2003;14(16):2095-8.
2003: Hitoshi Hashimoto; Akiyoshi Kunugi; Naohisa Arakawa; Norihito Shintani; Takashi Fujita; Atsushi Kasai; Chihiro Kawaguchi; Yoshiko Morita; Megumi Hirose; Yoshiyuki Sakai; Akemichi Baba
Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes.
Biochemical and biophysical research communications 2003;311(2):337-43.
2003: Norihito Shintani; Kazuhiro Tanaka; Hitoshi Hashimoto; Akemichi Baba
[Altered behavioral response to centrally acting drugs in mice lacking PACAP].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122 Suppl():1P-4P.
2003: Chihiro Kawaguchi; Kazuhiro Tanaka; Yasushi Isojima; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Katsuya Nagai
Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP.
Biochemical and biophysical research communications 2003;310(1):169-75.
2003: Masaki Sakaue; Yukio Ago; Akemichi Baba; Toshio Matsuda
The 5-HT1A receptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice.
Psychopharmacology 2003;170(1):73-9.
2003: Yutaka Koyama; Kimiko Tsujikawa; Toshio Matsuda; Akemichi Baba
Intracerebroventricular administration of an endothelin ETB receptor agonist increases expressions of GDNF and BDNF in rat brain.
The European journal of neuroscience 2003;18(4):887-94.
2003: Yutaka Koyama; Yasuhiro Yoshioka; Toshio Matsuda; Akemichi Baba
Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes.
Glia 2003;43(2):185-9.
2003: Ikuko Yokoyama; Yoshiyuki Sakai; Yuki Hatayama; Shingo Tsuji; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
T-588, a cognitive enhancer, stimulates in vivo phosphorylation of extracellular signal-regulated kinases in the hippocampus.
Brain research. Cognitive brain research 2003;17(2):522-5.
2003: Akiko Yamamuro; Yukio Ago; Sadaaki Maeda; Yoshiyuki Sakai; Akemichi Baba; Toshio Matsuda
Protective effect of T-588 on toxic damage by serum deprivation and amyloid-beta protein in cultured neurons.
Journal of pharmacological sciences 2003;92(2):153-6.
2003: Kyohei Yamamoto; Hitoshi Hashimoto; Shuhei Tomimoto; Norihito Shintani; Jun-ichi Miyazaki; Fumi Tashiro; Hiroyuki Aihara; Takao Nammo; Ming Li; Kazuya Yamagata; Jun-ichiro Miyagawa; Yuji Matsuzawa; Yuki Kawabata; Yuji Fukuyama; Kazumi Koga; Wakaba Mori; Kazuhiro Tanaka; Toshio Matsuda; Akemichi Baba
Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes.
Diabetes 2003;52(5):1155-62.
2003: Yutaka Koyama; Kimiko Tsujikawa; Toshio Matsuda; Akemichi Baba
Endothelin-1 stimulates glial cell line-derived neurotrophic factor expression in cultured rat astrocytes.
Biochemical and biophysical research communications 2003;303(4):1101-5.
2003: Kenzo Takahashi; Teisuke Takahashi; Taizo Suzuki; michihito onishi; Yu Tanaka; Akiko Hamano-Takahashi; Tomomi Ota; Kazuya Kameo; Toshio Matsuda; Akemichi Baba
Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries.
European journal of pharmacology 2003;458(1-2):155-62.
2003: Masaki Sakaue; Yukio Ago; Chikako Sowa; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
The 5-HT1A receptor agonist MKC-242 increases the exploratory activity of mice in the elevated plus-maze.
European journal of pharmacology 2003;458(1-2):141-4.
2003: Kazuhiro Takuma; Makiko Kiriu; Koichi Mori; Eibai Lee; Riyo Enomoto; Akemichi Baba; Toshio Matsuda
Roles of cathepsins in reperfusion-induced apoptosis in cultured astrocytes.
Neurochemistry international 2003;42(2):153-9.
2002: Yoshiyuki Sakai; Hitoshi Hashimoto; Norihito Shintani; Ayako Ichibori; Shuhei Tomimoto; Kazuhiro Tanaka; Megumi Hirose; Akemichi Baba
Involvement of intracellular Ca2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells.
Regulatory peptides 2002;109(1-3):149-53.
2002: Norihito Shintani; Wakaba Mori; Hitoshi Hashimoto; Masayuki Imai; Kazuhiro Tanaka; Shuhei Tomimoto; Megumi Hirose; Chihiro Kawaguchi; Akemichi Baba
Defects in reproductive functions in PACAP-deficient female mice.
Regulatory peptides 2002;109(1-3):45-8.
2002: Yukio Ago; Masaki Sakaue; Akemichi Baba; Toshio Matsuda
Selective reduction by isolation rearing of 5-HT1A receptor-mediated dopamine release in vivo in the frontal cortex of mice.
Journal of neurochemistry 2002;83(2):353-9.
2002: Hitoshi Hashimoto; Norihito Shintani; Akemichi Baba
Higher brain functions of PACAP and a homologous Drosophila memory gene amnesiac: insights from knockouts and mutants.
Biochemical and biophysical research communications 2002;297(3):427-31.
2002: Kazunori Mukai; Yuji Satoh; Akikazu Fujita; Tadayoshi Takeuchi; Norihito Shintani; Hitoshi Hashimoto; Akemichi Baba; Fumiaki Hata
PAC1 receptor-mediated relaxation of longitudinal muscle of the mouse proximal colon.
Japanese journal of pharmacology 2002;90(1):97-100.
2002: Kazuhiro Takuma; Koichi Mori; Eibai Lee; Riyo Enomoto; Akemichi Baba; Toshio Matsuda
Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes.
Brain research 2002;946(2):232-8.
2002: Kyoko Takahashi; Xinshou Ouyang; Katsuko Komatsu; Norio Nakamura; Masao Hattori; Akemichi Baba; Junichi Azuma
Sodium tanshinone IIA sulfonate derived from Danshen (Salvia miltiorrhiza) attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac cells.
Biochemical pharmacology 2002;64(4):745-9.
2002: Hannes Reuter; Scott A Henderson; Tieyan Han; Toshio Matsuda; Akemichi Baba; Robert S Ross; Joshua I Goldhaber; Kenneth D Philipson
Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors.
Circulation research 2002;91(2):90-2.
2002: Masaki Sakaue; Yukio Ago; Chikako Sowa; Yayoi Sakamoto; Beni Nishihara; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Modulation by 5-hT2A receptors of aggressive behavior in isolated mice.
Japanese journal of pharmacology 2002;89(1):89-92.
2002: Kazuhiro Takuma; Patamawan Phuagphong; Eibai Lee; Riyo Enomoto; Koichi Mori; Akemichi Baba; Toshio Matsuda
The nitric oxide donor NOC12 protects cultured astrocytes against apoptosis via a cGMP-dependent mechanism.
Japanese journal of pharmacology 2002;89(1):64-71.
2001: Kazuhiro Takuma; Patamawan Phuagphong; Eibai Lee; Koichi Mori; Akemichi Baba; Toshio Matsuda
Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore.
The Journal of biological chemistry 2001;276(51):48093-9.
2001: Masaki Sakaue; Yukio Ago; C Murakami; Chikako Sowa; Yayoi Sakamoto; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Involvement of benzodiazepine binding sites in an antiaggressive effect by 5-HT(1A) receptor activation in isolated mice.
European journal of pharmacology 2001;432(2-3):163-6.
2001: X Ouyang; K Takahashi; K Komatsu; N Nakamura; M Hattori; Akemichi Baba; J Azuma
Protective effect of Salvia miltiorrhiza on angiotensin II-induced hypertrophic responses in neonatal rat cardiac cells.
Japanese journal of pharmacology 2001;87(4):289-96.
2001: Hisashi Hashimoto; Norihito Shintani; Keiichi Tanaka; Wakaba Mori; Megumi Hirose; Toshio Matsuda; M Sakaue; Jun-ichi Miyazaki; Hitoshi Niwa; Fumi Tashiro; Koji Yamamoto; Kazumi Koga; Shuhei Tomimoto; Akiyoshi Kunugi; S Suetake; Akemichi Baba
Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP).
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13355-60.
2001: Toshio Matsuda; Masaki Sakaue; Yukio Ago; Yayoi Sakamoto; Yutaka Koyama; Akemichi Baba
Functional alteration of brain dopaminergic system in isolated aggressive mice.
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2001;21(3):71-6.
2001: Yoshiyuki Sakai; Hisashi Hashimoto; Norihito Shintani; Shuhei Tomimoto; Keiichi Tanaka; Ayako Ichibori; Megumi Hirose; Akemichi Baba
Involvement of p38 MAP kinase pathway in the synergistic activation of PACAP mRNA expression by NGF and PACAP in PC12h cells.
Biochemical and biophysical research communications 2001;285(3):656-61.
2001: Kazuhiro Takuma; Eibai Lee; Riyo Enomoto; Koichi Mori; Akemichi Baba; Toshio Matsuda
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model.
British journal of pharmacology 2001;133(6):841-8.
2001: Toshio Matsuda; Naohisa Arakawa; Kazuhiro Takuma; Yuki Kishida; Yasushi Kawasaki; M Sakaue; Kiyohisa Takahashi; T Takahashi; T Suzuki; T Ota; A Hamano-Takahashi; michihito onishi; Y Tanaka; Kazuya Kameo; Akemichi Baba
SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.
The Journal of pharmacology and experimental therapeutics 2001;298(1):249-56.
2001: Akemichi Baba; Naoko Abe; Tomoko Kadowaki; H Nakanishi; Masamichi Ohishi; Tetsuji Asao; Kenji Yamamoto
Arg-gingipain is responsible for the degradation of cell adhesion molecules of human gingival fibroblasts and their death induced by Porphyromonas gingivalis.
Biological chemistry 2001;382(5):817-24.
2000: Norihito Shintani; Hisashi Hashimoto; Akiyoshi Kunugi; Yutaka Koyama; Koji Yamamoto; Shuhei Tomimoto; Wakaba Mori; Toshio Matsuda; Akemichi Baba
Desensitization, surface expression, and glycosylation of a functional, epitope-tagged type I PACAP (PAC(1)) receptor.
Biochimica et biophysica acta 2000;1509(1-2):195-202.
2000: Naohisa Arakawa; M Sakaue; I Yokoyama; Hisashi Hashimoto; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
KB-R7943 inhibits store-operated Ca(2+) entry in cultured neurons and astrocytes.
Biochemical and biophysical research communications 2000;279(2):354-7.
2000: Naoko Abe; Akemichi Baba; Tomoko Kadowaki; Kuniaki Okamoto; S Okazaki; Tetsuji Asao; Kenji Yamamoto
Design and synthesis of sensitive fluorogenic substrates specific for Lys-gingipain.
Journal of biochemistry 2000;128(5):877-81.
2000: Hisashi Hashimoto; Norihito Shintani; A Nishino; M Okabe; M Ikawa; S Matsuyama; K Itoh; Koji Yamamoto; Shuhei Tomimoto; Takashi Fujita; N Hagihara; Wakaba Mori; Yutaka Koyama; Toshio Matsuda; S Nagata; Akemichi Baba
Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide.
Journal of neurochemistry 2000;75(5):1810-7.
2000: M Sakaue; H Nakamura; I Kaneko; Yasushi Kawasaki; Naohisa Arakawa; Hisashi Hashimoto; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
Na(+)-Ca(2+) exchanger isoforms in rat neuronal preparations: different changes in their expression during postnatal development.
Brain research 2000;881(2):212-6.
2000: Kazuhiro Takuma; T Yoshida; Eibai Lee; K Mori; T Kishi; Akemichi Baba; Toshio Matsuda
CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production.
European journal of pharmacology 2000;406(3):333-9.
2000: Yutaka Koyama; Y Kimura; Y Yoshioka; D Wakamatsu; R Kozaki; Hisashi Hashimoto; Toshio Matsuda; Akemichi Baba
Serum-deprivation induces cell death of rat cultured microglia accompanied with expression of Bax protein.
Japanese journal of pharmacology 2000;83(4):351-4.
2000: Tomoko Kadowaki; Kei-Ichi Nakayama; Kuniaki Okamoto; Naoko Abe; Akemichi Baba; Yixin Shi; Dinath B Ratnayake; Kenji Yamamoto
Porphyromonas gingivalis proteinases as virulence determinants in progression of periodontal diseases.
Journal of biochemistry 2000;128(2):153-9.
2000: Kazuhiro Takuma; T Fujita; Y Kimura; M Tanabe; Akiko Yamamuro; Eibai Lee; K Mori; Y Koyama; Akemichi Baba; Toshio Matsuda
T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway.
European journal of pharmacology 2000;399(1):1-8.
2000: H Nakamura; Yasushi Kawasaki; Naohisa Arakawa; Makio Saeki; Sadaaki Maeda; Yutaka Koyama; Akemichi Baba; Toshio Matsuda
The Na+-Ca2+ exchange inhibitor KB-R7943 inhibits high K+-induced increases in intracellular Ca2+ concentration and [3H]noradrenaline release in the human neuroblastoma SH-SY5Y.
Neurochemical research 2000;25(3):385-7.
2000: Masaki Sakaue; Pranee Somboonthum; B Nishihara; Yutaka Koyama; Hitoshi Hashimoto; Akemichi Baba; Toshio Matsuda
Postsynaptic 5-hydroxytryptamine(1A) receptor activation increases in vivo dopamine release in rat prefrontal cortex.
British journal of pharmacology 2000;129(5):1028-34.
2000: Yutaka Koyama; Y Kimura; H Hashimoto; Toshio Matsuda; Akemichi Baba
L-lactate inhibits L-cystine/L-glutamate exchange transport and decreases glutathione content in rat cultured astrocytes.
Journal of neuroscience research 2000;59(5):685-91.
2000: Y Koyama; T Ishibashi; T Okamoto; Toshio Matsuda; H Hashimoto; Akemichi Baba
Transient treatments with L-glutamate and threo-beta-hydroxyaspartate induce swelling of rat cultured astrocytes.
Neurochemistry international 2000;36(2):167-73.
2000: Hisashi Hashimoto; N Hagihara; Kazumi Koga; Koji Yamamoto; Norihito Shintani; Shuhei Tomimoto; Wakaba Mori; Yutaka Koyama; Toshio Matsuda; Akemichi Baba
Synergistic induction of pituitary adenylate cyclase-activating polypeptide (PACAP) gene expression by nerve growth factor and PACAP in PC12 cells.
Journal of neurochemistry 2000;74(2):501-7.
2000: Yutaka Koyama; Y Yoshioka; Hisashi Hashimoto; Toshio Matsuda; Akemichi Baba
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Neuroscience 2000;101(1):219-27.
1999: K Takuma; E Lee; M Kidawara; K Mori; Y Kimura; Akemichi Baba; Toshio Matsuda
Apoptosis in Ca2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activation.
The European journal of neuroscience 1999;11(12):4204-12.
1999: Toshio Matsuda; Kazuhiro Takuma; E Lee; Akemichi Baba
[Cell injury and its protection in astrocytes].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;114(5):281-6.
1999: Yutaka Koyama; T Mizobata; N Yamamoto; Hisashi Hashimoto; Toshio Matsuda; Akemichi Baba
Endothelins stimulate expression of cyclooxygenase 2 in rat cultured astrocytes.
Journal of neurochemistry 1999;73(3):1004-11.
1999: Yutaka Koyama; Akemichi Baba
Endothelin-induced protein tyrosine phosphorylation of cultured astrocytes: its relationship to cytoskeletal actin organization.
Glia 1999;26(4):324-32.
1999: Hisashi Hashimoto; A Nishino; Norihito Shintani; N Hagihara; Neal G Copeland; NA Jenkins; Koji Yamamoto; Toshio Matsuda; T Ishihara; S Nagata; Akemichi Baba
Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor.
Genomics 1999;58(1):90-3.
1999: Yutaka Koyama; M Takemura; K Fujiki; N Ishikawa; Y Shigenaga; Akemichi Baba
BQ788, an endothelin ET(B) receptor antagonist, attenuates stab wound injury-induced reactive astrocytes in rat brain.
Glia 1999;26(3):268-71.
1998: Toshio Matsuda; Kazuhiro Takuma; E Lee; Y Kimura; Takashi Fujita; Akemichi Baba
[Apoptosis of astroglial cells].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;112 Suppl 1():24P-27P.
1998: Toshio Matsuda; Kazuhiro Takuma; S Asano; Yuki Kishida; H Nakamura; K Mori; S Maeda; Akemichi Baba
Involvement of calcineurin in Ca2+ paradox-like injury of cultured rat astrocytes.
Journal of neurochemistry 1998;70(5):2004-11.
1998: Koji Yamamoto; Hisashi Hashimoto; N Hagihara; A Nishino; Takashi Fujita; Toshio Matsuda; Akemichi Baba
Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene.
Gene 1998;211(1):63-9.
1998: Akemichi Baba
Role of endothelin B receptor signals in reactive astrocytes.
Life sciences 1998;62(17-18):1711-5.
1998: Toshio Matsuda; Akemichi Baba
[Response of Na+/Ca2+ antiporter to ischemia and glial/neuronal death].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;111(1):13-9.
1997: Pranee Somboonthum; Toshio Matsuda; S Asano; Masaki Sakaue; Akemichi Baba
MKC-242, a novel 5-HT1A receptor agonist, facilitates cortical acetylcholine release by a mechanism different from that of 8-OH-DPAT in awake rats.
Neuropharmacology 1997;36(11-12):1733-9.
1997: Rie Hosoi; Toshio Matsuda; S Asano; H Nakamura; Hisashi Hashimoto; Kazuhiro Takuma; Akemichi Baba
Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes.
Journal of neurochemistry 1997;69(5):2189-96.
1997: H Nogi; Hisashi Hashimoto; Takashi Fujita; N Hagihara; Toshio Matsuda; Akemichi Baba
Pituitary adenylate cyclase-activating polypeptide (PACAP) receptor mRNA in the rat adrenal gland: localization by in situ hybridization and identification of splice variants.
Japanese journal of pharmacology 1997;75(2):203-7.
1997: S Asano; Toshio Matsuda; Y Nakasu; S Maeda; H Nogi; Akemichi Baba
Inhibition by nitric oxide of the uptake of [3H]serotonin into rat brain synaptosomes.
Japanese journal of pharmacology 1997;75(2):123-8.
1997: Hisashi Hashimoto; N Ogawa; N Hagihara; Koji Yamamoto; K Imanishi; H Nogi; A Nishino; Takashi Fujita; Toshio Matsuda; S Nagata; Akemichi Baba
Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide receptor chimeras reveal domains that determine specificity of vasoactive intestinal polypeptide binding and activation.
Molecular pharmacology 1997;52(1):128-35.
1997: H Nogi; Hisashi Hashimoto; N Hagihara; Shoichi Shimada; Koji Yamamoto; Toshio Matsuda; Masaya Tohyama; Akemichi Baba
Distribution of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), PACAP receptor, vasoactive intestinal polypeptide (VIP), and VIP receptors in the rat superior cervical ganglion.
Neuroscience letters 1997;227(1):37-40.
1997: S Asano; Toshio Matsuda; T Yoshikawa; Pranee Somboonthum; H Tasaki; M Abe; Akemichi Baba
Interaction of orally administered 5-[3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy]-1,3-benzodioxole (MKC-242) with 5-HT1A receptors in rat brain.
Japanese journal of pharmacology 1997;74(1):69-75.
1997: Toshio Matsuda; Kazuhiro Takuma; Akemichi Baba
Na(+)-Ca2+ exchanger: physiology and pharmacology.
Japanese journal of pharmacology 1997;74(1):1-20.
1997: N Ishikawa; M Takemura; Yutaka Koyama; Y Shigenaga; T Okada; Akemichi Baba
Endothelins promote the activation of astrocytes in rat neostriatum through ET(B) receptors.
The European journal of neuroscience 1997;9(5):895-901.
1997: Yutaka Koyama; Y Kimura; Akemichi Baba
Induction of glutamine synthetase by L-alpha-aminoadipate in developmental stages of cultured astrocytes.
Neuroscience letters 1997;223(1):65-8.
1997: Yutaka Koyama; Akira Awaya; N Ishikawa; Shigeo Fujita; I Tomino; K Yokoyama; S Araki; M Takesue; K Kato; M Ishiguro; T Kitahara; N Kihara; Akemichi Baba
Neurotropic pyrimidine heterocyclic compounds. II. Effects of novel neurotropic pyrimidine derivatives on astrocytic morphological differentiation.
Biological & pharmaceutical bulletin 1997;20(2):138-41.
1996: Y Murata; Toshio Matsuda; K Tamada; Rie Hosoi; S Asano; Kazuhiro Takuma; K Tanaka; Akemichi Baba
Ouabain-induced cell proliferation in cultured rat astrocytes.
Japanese journal of pharmacology 1996;72(4):347-53.
1996: Kazuhiro Takuma; Toshio Matsuda; Hisashi Hashimoto; Junichi Kitanaka; S Asano; Y Kishida; Akemichi Baba
Role of Na(+)-Ca2+ exchanger in agonist-induced Ca2+ signaling in cultured rat astrocytes.
Journal of neurochemistry 1996;67(5):1840-5.
1996: Kazuhiro Takuma; Toshio Matsuda; Y Kishida; S Asano; Y H Seong; Akemichi Baba
Heat shock protects cultured rat astrocytes in a model of reperfusion injury.
Brain research 1996;735(2):265-70.
1996: Kazuhiro Takuma; Toshio Matsuda; Y Kishida; S Asano; Junichi Azuma; Akemichi Baba
Ca2+ depletion facilitates taurine release in cultured rat astrocytes.
Japanese journal of pharmacology 1996;72(1):75-8.
1996: Hisashi Hashimoto; H Nogi; K Mori; H Ohishi; R Shigemoto; K Yamamoto; Toshio Matsuda; N Mizuno; S Nagata; Akemichi Baba
Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study.
The Journal of comparative neurology 1996;371(4):567-77.
1996: Hisashi Hashimoto; K Yamamoto; N Hagigara; N Ogawa; A Nishino; H Aino; H Nogi; K Imanishi; Toshio Matsuda; Akemichi Baba
cDNA cloning of a mouse pituitary adenylate cyclase-activating polypeptide receptor.
Biochimica et biophysica acta 1996;1281(2):129-33.
1996: Junichi Kitanaka; Kazuhiro Takuma; K Kondo; Akemichi Baba
Prostanoid receptor-mediated calcium signaling in cultured rat astrocytes.
Japanese journal of pharmacology 1996;71(1):85-7.
1996: Toshio Matsuda; Kazuhiro Takuma; E Nishiguchi; Hisashi Hashimoto; Junichi Azuma; Akemichi Baba
Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytes.
The European journal of neuroscience 1996;8(5):951-8.
1996: Yutaka Koyama; Akemichi Baba
Endothelin-induced cytoskeletal actin re-organization in cultured astrocytes: inhibition by C3 ADP-ribosyltransferase.
Glia 1996;16(4):342-50.
1996: Toshio Matsuda; Y Murata; K Tanaka; Rie Hosoi; Mitsuko Hayashi; K Tamada; Kazuhiro Takuma; Akemichi Baba
Involvement of Na+,K(+)ATPase in the mitogenic effect of insulin-like growth factor-I on cultured rat astrocytes.
Journal of neurochemistry 1996;66(2):511-6.
1996: Junichi Kitanaka; Hisashi Hashimoto; M Gotoh; K Kondo; K Sakata; Y Hirasawa; M Sawada; A Suzumura; T Marunouchi; Toshio Matsuda; Akemichi Baba
Expression pattern of messenger RNAs for prostanoid receptors in glial cell cultures.
Brain research 1996;707(2):282-7.
1996: Yutaka Koyama; Tsuyoshi Fukuda; Akemichi Baba
Inhibition of vanadate-induced astrocytic stress fiber formation by C3 ADP-ribosyltransferase.
Biochemical and biophysical research communications 1996;218(1):331-6.
1996: Toshio Matsuda; Kazuhiro Takuma; Y Kishida; Junichi Azuma; Akemichi Baba
Protective effect of taurine against reperfusion injury in cultured rat astrocytes.
Advances in experimental medicine and biology 1996;403():491-7.
1996: Kyoko Takahashi; H Hashimoto; Akemichi Baba; S W Schaffer; Junichi Azuma
Effect of taurine on angiotensin II-induced expression of immediate early response genes in primary cultured neonatal rat heart cells.
Advances in experimental medicine and biology 1996;403():297-304.
1995: H Aino; Hisashi Hashimoto; N Ogawa; A Nishino; K Yamamoto; H Nogi; S Nagata; Akemichi Baba
Structure of the gene encoding the mouse pituitary adenylate cyclase-activating polypeptide receptor.
Gene 1995;164(2):301-4.
1995: Yutaka Koyama; T Ishibashi; Akemichi Baba
Increase in chloride-dependent L-glutamate transport activity in synaptic membrane after in vitro ischemic treatment.
Journal of neurochemistry 1995;65(4):1798-804.
1995: Toshio Matsuda; Pranee Somboonthum; M Suzuki; S Asano; Akemichi Baba
Antidepressant-like effect by postsynaptic 5-HT1A receptor activation in mice.
European journal of pharmacology 1995;280(2):235-8.
1995: S Asano; Toshio Matsuda; Kazuhiro Takuma; H S Kim; T Sato; T Nishikawa; Akemichi Baba
Nitroprusside and cyclic GMP stimulate Na(+)-Ca2+ exchange activity in neuronal preparations and cultured rat astrocytes.
Journal of neurochemistry 1995;64(6):2437-41.
1995: M Suzuki; Toshio Matsuda; S Asano; Pranee Somboonthum; Kazuhiro Takuma; Akemichi Baba
Increase of noradrenaline release in the hypothalamus of freely moving rat by postsynaptic 5-hydroxytryptamine1A receptor activation.
British journal of pharmacology 1995;115(4):703-11.
1995: Kazuhiro Takuma; Toshio Matsuda; S Asano; Akemichi Baba
Intracellular ascorbic acid inhibits the Na(+)-Ca2+ exchanger in cultured rat astrocytes.
Journal of neurochemistry 1995;64(4):1536-40.
1995: M Suzuki; Toshio Matsuda; Pranee Somboonthum; S Asano; Kazuhiro Takuma; H Nogi; Akemichi Baba
Effects of serotonin1A agonists on anoxia-induced impairment of protein synthesis in rat brain slices.
Japanese journal of pharmacology 1995;67(4):403-5.
1995: K Kondo; Hisashi Hashimoto; K Sakata; H Saga; Junichi Kitanaka; Akemichi Baba
Stimulation of cyclic AMP formation by pituitary adenylate cyclase-activating polypeptide is attenuated by glutamate in rat brain slices.
Japanese journal of pharmacology 1995;67(4):399-401.
1995: K Kondo; Hisashi Hashimoto; Junichi Kitanaka; M Sawada; A Suzumura; T Marunouchi; Akemichi Baba
Expression of glutamate transporters in cultured glial cells.
Neuroscience letters 1995;188(2):140-2.
1995: Junichi Kitanaka; Hisashi Hashimoto; Y Sugimoto; M Sawada; M Negishi; A Suzumura; T Marunouchi; A Ichikawa; Akemichi Baba
cDNA cloning of a thromboxane A2 receptor from rat astrocytes.
Biochimica et biophysica acta 1995;1265(2-3):220-3.
1994: Kazuhiro Takuma; Toshio Matsuda; Hisashi Hashimoto; S Asano; Akemichi Baba
Cultured rat astrocytes possess Na(+)-Ca2+ exchanger.
Glia 1994;12(4):336-42.
1994: Junichi Kitanaka; T Hamano; M Gotoh; Hisashi Hashimoto; Akemichi Baba
Tunicamycin inhibits prostaglandin F2 alpha receptor-mediated phosphoinositide hydrolysis in cultured rat astrocytes.
Neurochemical research 1994;19(12):1545-50.
1994: Yutaka Koyama; Akemichi Baba
Endothelins are extracellular signals modulating cytoskeletal actin organization in rat cultured astrocytes.
Neuroscience 1994;61(4):1007-16.
1994: Hiroyuki Mizuguchi; Y Hashioka; A Fujii; Naoki Utoguchi; K Kubo; Shinsaku Nakagawa; Akemichi Baba; Tadanori Mayumi
Glial extracellular matrix modulates gamma-glutamyl transpeptidase activity in cultured bovine brain capillary and bovine aortic endothelial cells.
Brain research 1994;651(1-2):155-9.
1994: Junichi Kitanaka; H Hasimoto; Y Sugimoto; M Negishi; H Aino; M Gotoh; A Ichikawa; Akemichi Baba
Cloning and expression of a cDNA for rat prostaglandin F2 alpha receptor.
Prostaglandins 1994;48(1):31-41.
1994: M Gotoh; Junichi Kitanaka; Y Hirasawa; K Kondo; Akemichi Baba
Desensitization of prostaglandin F2 alpha receptor-mediated phosphoinositide hydrolysis in cultured rat astrocytes.
Neurochemical research 1994;19(6):679-85.
1994: Yutaka Koyama; T Ishibashi; K Tanaka; Akemichi Baba
L-glutamate-stimulated taurine release from rat cerebral cultured astrocytes.
Journal of neuroscience research 1994;38(1):75-80.
1994: Hisashi Hashimoto; H Aino; N Ogawa; S Nagata; Akemichi Baba
Identification and characterization of parathyroid hormone/parathyroid hormone-related peptide receptor in cultured astrocytes.
Biochemical and biophysical research communications 1994;200(2):1042-8.
1994: Kazuhiro Takuma; Toshio Matsuda; T Yoshikawa; Junichi Kitanaka; M Gotoh; K Hayata; Akemichi Baba
Corticotropin-releasing factor stimulates Ca2+ influx in cultured rat astrocytes.
Biochemical and biophysical research communications 1994;199(3):1103-7.
1993: Toshio Matsuda; Y Murata; N Kawamura; Mitsuko Hayashi; K Tamada; Kazuhiro Takuma; S Maeda; Akemichi Baba
Selective induction of alpha 1 isoform of (Na+ + K+)-ATPase by insulin/insulin-like growth factor-I in cultured rat astrocytes.
Archives of biochemistry and biophysics 1993;307(1):175-82.
1993: Yutaka Koyama; T Ishibashi; H Iwata; Akemichi Baba
Pretreatment of rat brain slices with ouabain decreases chloride-dependent L-glutamate transport in synaptic membrane.
Neurochemistry international 1993;23(2):149-55.
1993: Junichi Kitanaka; S Maeda; Akemichi Baba
Cytochalasin B inhibits phosphoinositide hydrolysis in rat hippocampal slices.
Neurochemical research 1993;18(2):225-9.
1993: Junichi Kitanaka; T Ishibashi; Akemichi Baba
Phloretin as an antagonist of prostaglandin F2 alpha receptor in cultured rat astrocytes.
Journal of neurochemistry 1993;60(2):704-8.
1993: Akemichi Baba; H Saga; Hisashi Hashimoto
Inhibitory glutamate response on cyclic AMP formation in cultured astrocytes.
Neuroscience letters 1993;149(2):182-4.
1993: Yutaka Koyama; T Ishibashi; K Hayata; Akemichi Baba
Endothelins modulate dibutyryl cAMP-induced stellation of cultured astrocytes.
Brain research 1993;600(1):81-8.
1992: Junichi Kitanaka; Hisashi Hashimoto; M Gotoh; Tadanori Mayumi; Akemichi Baba
Mechanism of extracellular ATP-stimulated phosphoinositide hydrolysis in rat glioma C6 cells.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1248-52.
1992: Y Nakano; Toshio Matsuda; Kazuhiro Takuma; T Yoshikawa; Akemichi Baba
Sex difference for tolerance of 5-HT1A receptor-mediated temperature and corticosterone responses in mice.
European journal of pharmacology 1992;219(2):339-41.
1992: Akemichi Baba
[Regulation by chloride ion of astroglial cell functions and morphological transformation].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1992;99(5):297-305.
1992: Toshio Matsuda; I Shimizu; Y Murata; Akemichi Baba
Glucose and oxygen deprivation induces a Ca(2+)-mediated decrease in (Na(+)+K+)-ATPase activity in rat brain slices.
Brain research 1992;576(2):263-70.
1992: Toshio Matsuda; I Shimizu; Akemichi Baba
Postnatal change in a Ca(2+)-mediated decrease in (Na+ + K+)-ATPase activity in rat brain slices.
Brain research 1992;572(1-2):349-51.
1992: Junichi Kitanaka; Akemichi Baba
Effect of dibutyryl cyclic AMP-treatment on prostaglandin F2 alpha-stimulated phosphoinositide hydrolysis in cultured rat astrocytes.
Japanese journal of pharmacology 1992;58(2):189-92.
1992: Yutaka Koyama; T Ishibashi; Akemichi Baba
L-glutamate-induced swelling of cultured astrocytes.
Advances in experimental medicine and biology 1992;315():375-80.
1991: Toshio Matsuda; I Shimizu; Akemichi Baba
Na+ influx-induced decrease of (Na+ + K+)-ATPase activity in rat brain slices: role of Ca2+.
European journal of pharmacology 1991;204(3):257-63.
1991: Akemichi Baba; S Etoh; H Iwata
Inhibition of NMDA-induced protein kinase C translocation by a Zn2+ chelator: implication of intracellular Zn2+.
Brain research 1991;557(1-2):103-8.
1991: Junichi Kitanaka; Hirotaka Onoe; Akemichi Baba
Astrocytes possess prostaglandin F2 alpha receptors coupled to phospholipase C.
Biochemical and biophysical research communications 1991;178(3):946-52.
1991: Toshio Matsuda; Y Nakano; T Kanda; H Iwata; Akemichi Baba
Gonadectomy changes the pituitary-adrenocortical response in mice to 5-HT1A receptor agonists.
European journal of pharmacology 1991;200(2-3):299-304.
1991: S Etoh; Akemichi Baba; H Iwata
NMDA induces protein kinase C translocation in guinea pig cerebral synaptoneurosomes.
Japanese journal of pharmacology 1991;56(3):287-96.
1991: S Etoh; Akemichi Baba; H Iwata
NMDA induces protein kinase C translocation in hippocampal slices of immature rat brain.
Neuroscience letters 1991;126(2):119-22.
1991: Yutaka Koyama; T Sugimoto; Y Shigenaga; Akemichi Baba; H Iwata
A morphological study on glutamate-induced swelling of cultured astrocytes: involvement of calcium and chloride ion mechanisms.
Neuroscience letters 1991;124(2):235-8.
1991: Yutaka Koyama; Akemichi Baba; H Iwata
L-glutamate-induced swelling of cultured astrocytes is dependent on extracellular Ca2+.
Neuroscience letters 1991;122(2):210-2.
1991: Toshio Matsuda; H Tonomura; Akemichi Baba; H Iwata
Postnatal development of thiamine metabolism in rat skeletal muscle.
The International journal of biochemistry 1991;23(2):203-6.
1991: Toshio Matsuda; Y Nakano; T Kanda; H Iwata; Akemichi Baba
Gonadal hormones affect the hypothermia induced by serotonin1A (5-HT1A) receptor activation.
Life sciences 1991;48(17):1627-32.
1991: Toshio Matsuda; H Tonomura; Akemichi Baba; H Iwata
Membrane-associated thiamine triphosphatase in rat skeletal muscle.
The International journal of biochemistry 1991;23(10):1111-4.
1990: Yutaka Koyama; Akemichi Baba; H Iwata
Characteristics of Cl(-)-dependent L-[35S]cysteic acid transport into rat brain synaptic membrane vesicles.
Neurochemical research 1990;15(12):1153-8.
1990: Toshio Matsuda; T Gemba; Akemichi Baba; H Iwata
Decrease of Na(+)-Ca2+ exchange activity by ascorbate in rat brain membrane vesicles.
Brain research 1990;532(1-2):13-8.
1990: Y H Seong; Akemichi Baba; Toshio Matsuda; H Iwata
5-Hydroxytryptamine modulation of electrically induced twitch responses of mouse vas deferens: involvement of multiple 5-hydroxytryptamine receptors.
The Journal of pharmacology and experimental therapeutics 1990;254(3):1012-6.
1990: S Etoh; M Ohashi; Akemichi Baba; H Iwata
Inhibition by ibudilast of leukotriene D4-induced formation of inositol phosphates in guinea-pig lung.
British journal of pharmacology 1990;100(3):564-8.
1990: H Yara; Y Katagawa; Mitsunobu Doi; Toshimasa Ishida; M Inoue; M Yasuda; Akemichi Baba; H Iwata; Kunihiro Kitamura; T Sadatome
An attempt to structurally convert mu-selective morphine toward delta-receptor binding: dimerization based on enkephalin conformation.
European journal of pharmacology 1990;188(6):359-68.
1990: Toshio Matsuda; T Kanda; Y H Seong; Akemichi Baba; H Iwata
p-chlorophenylalanine attenuates the pituitary-adrenocortical response to 5-HT1A receptor agonists in mice.
European journal of pharmacology 1990;181(3):295-7.
1990: H Iwata; Yutaka Koyama; A Uemura; H Tanaka; M Noda; Akemichi Baba
Chloride-dependent amino acid transport in synaptic membrane vesicles.
Progress in clinical and biological research 1990;351():259-66.
1989: Toshio Matsuda; Y H Seong; H Aono; T Kanda; Akemichi Baba; K Saito; A Tobe; H Iwata
Agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (BP-554), at central 5-HT1A receptors.
European journal of pharmacology 1989;170(1-2):75-82.
1989: Akemichi Baba; S Sakuma; H Okamoto; T Inoue; H Iwata
Calcium induces membrane translocation of 12-lipoxygenase in rat platelets.
The Journal of biological chemistry 1989;264(27):15790-5.
1989: Yutaka Koyama; Akemichi Baba; H Iwata
L-[35S]cysteic acid selectively detects chloride-dependent L-glutamate transporters in synaptic membrane.
Brain research 1989;487(1):113-9.
1989: Akemichi Baba; Takeshi Kihara; T Sawada; H Iwata
Excitatory amino acids enhance dissociation of zinc from soluble protein in cytosol of rat hippocampus.
Brain research 1989;486(2):372-5.
1989: Toshio Matsuda; T Doi; H Tonomura; Akemichi Baba; H Iwata
Postnatal development of thiamine metabolism in rat brain.
Journal of neurochemistry 1989;52(3):842-6.
1989: H Iwata; Yutaka Koyama; Akemichi Baba
Depolarization increases chloride-dependent glutamate sequestration in synaptic membranes of rat cerebral cortex.
Journal of neurochemistry 1989;52(2):354-9.
1989: Toshio Matsuda; H Tonomura; Akemichi Baba; H Iwata
Tissue difference in cellular localization of thiamine phosphate esters.
Comparative biochemistry and physiology. B, Comparative biochemistry 1989;94(2):405-9.
1989: Toshio Matsuda; T Gemba; Akemichi Baba; H Iwata
Inhibition by taurine of Na(+)-Ca2+ exchange in sarcolemmal membrane vesicles from bovine and guinea pig hearts.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1989;94(1):335-9.
1989: Toshio Matsuda; H Tonomura; Akemichi Baba; H Iwata
Difference in thiamine metabolism between extensor digitorum longus and soleus muscles.
Comparative biochemistry and physiology. B, Comparative biochemistry 1989;94(2):399-403.
1988: Akemichi Baba; Y Nishiuchi; A Uemura; T Tatsuno; H Iwata
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Journal of neurochemistry 1988;51(1):237-42.
1988: Akemichi Baba; Y Nishiuchi; A Uemura; H Iwata
Mechanism of excitatory amino acid-induced accumulation of cyclic AMP in hippocampal slices: role of extracellular chloride.
The Journal of pharmacology and experimental therapeutics 1988;245(1):299-304.
1987: A Ohta; Akemichi Baba; H Iwata
Effect of 5-(3-[4-(4-fluorophenyl)-1-piperazinyl]-propoxy)indan (BP-528) on benzodiazepine receptor bindings and gamma-aminobutyric acid release.
Japanese journal of pharmacology 1987;44(4):493-7.
1987: H Iwata; B K Kim; Y Fukui; Akemichi Baba
Neural regulation of taurine transport in skeletal muscle.
Advances in experimental medicine and biology 1987;217():199-205.
1987: Akemichi Baba; Yutaka Koyama; H Morimoto; H Iwata
Neurochemical characterization of excitatory amino acid receptors in hippocampus.
Advances in experimental medicine and biology 1987;217():319-24.