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David Johnson

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TOP 3
Jie Chen; Feng Zhu; Regina L Weaks; Anup K Biswas; Ruifeng Guo; Yanjie Li; David G Johnson
E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks.
Feng Zhu; Martijn E T Dollé; Thomas R Berton; Raoul V Kuiper; Carrie Capps; Alexsandra Espejo; Mark J McArthur; Mark T Bedford; Harry van Steeg; Annemieke de Vries; David G Johnson
Mouse models for the p53 R72P polymorphism mimic human phenotypes.
Raju V Pusapati; Regina L Weaks; Robert J Rounbehler; Mark J McArthur; David G Johnson
E2F2 suppresses Myc-induced proliferation and tumorigenesis.

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All Publications

2011: Jie Chen; Feng Zhu; Regina L Weaks; Anup K Biswas; Ruifeng Guo; Yanjie Li; David G Johnson
E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks.
Cell cycle (Georgetown, Tex.) 2011;10(8):1287-94.
2010: Feng Zhu; Martijn E T Dollé; Thomas R Berton; Raoul V Kuiper; Carrie Capps; Alexsandra Espejo; Mark J McArthur; Mark T Bedford; Harry van Steeg; Annemieke de Vries; David G Johnson
Mouse models for the p53 R72P polymorphism mimic human phenotypes.
Cancer research 2010;70(14):5851-9.
2010: Raju V Pusapati; Regina L Weaks; Robert J Rounbehler; Mark J McArthur; David G Johnson
E2F2 suppresses Myc-induced proliferation and tumorigenesis.
Molecular carcinogenesis 2010;49(2):152-6.
2009: Paola Rojas; Fernando Benavides; Jorge Blando; Carlos Perez; Kim Cardenas; Ellen R Richie; Erik S Knudsen; David G Johnson; Adrian M Senderowicz; Marcelo L Rodriguez-Puebla; Claudio J Conti
Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b).
Molecular carcinogenesis 2009;48(6):508-16.
2008: Q X Paulson; R V Pusapati; S Hong; R L Weaks; Claudio J Conti; David G Johnson
Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.
Oncogene 2008;27(36):4954-61.
2008: Sungki Hong; Qiwei X Paulson; David G Johnson
E2F1 and E2F3 activate ATM through distinct mechanisms to promote E1A-induced apoptosis.
Cell cycle (Georgetown, Tex.) 2008;7(3):391-400.
2006: David G Johnson; James DeGregori
Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context.
Current molecular medicine 2006;6(7):731-8.
2006: Sungki Hong; Raju V Pusapati; John T Powers; David G Johnson
Oncogenes and the DNA damage response: Myc and E2F1 engage the ATM signaling pathway to activate p53 and induce apoptosis.
Cell cycle (Georgetown, Tex.) 2006;5(8):801-3.
2006: J L Russell; R L Weaks; Thomas R Berton; David G Johnson
E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Oncogene 2006;25(6):867-76.
2006: Raju V Pusapati; Robert J Rounbehler; SungKi Hong; John T Powers; Mingshan Yan; Kaoru Kiguchi; Mark J McArthur; Paul K Wong; David G Johnson
ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1446-51.
2006: Qiwei X Paulson; Mark J McArthur; David G Johnson
E2F3a stimulates proliferation, p53-independent apoptosis and carcinogenesis in a transgenic mouse model.
Cell cycle (Georgetown, Tex.) 2006;5(2):184-90.
2005: Thomas R Berton; David L Mitchell; Ruifeng Guo; David G Johnson
Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation.
Oncogene 2005;24(15):2449-60.
2005: Joyce E Rundhaug; Kathleen A Hawkins; Amy Pavone; Sally Gaddis; Hyunsuk Kil; Russell D Klein; Thomas R Berton; Elisabeth McCauley; David G Johnson; Ronald A Lubet; Susan M Fischer; C Marcelo Aldaz
SAGE profiling of UV-induced mouse skin squamous cell carcinomas, comparison with acute UV irradiation effects.
Molecular carcinogenesis 2005;42(1):40-52.
2004: Paula L Miliani de Marval; Everardo Macias; Robert J Rounbehler; Piotr Sicinski; Hiroaki Kiyokawa; David G Johnson; Claudio J Conti; Marcelo L Rodriguez-Puebla
Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues.
Molecular and cellular biology 2004;24(17):7538-47.
2004: John T Powers; SungKi Hong; Christopher N Mayhew; Pamela M Rogers; Erik S Knudsen; David G Johnson
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
Molecular cancer research : MCR 2004;2(4):203-14.
2003: Thomas R Berton; Takashi Matsumoto; Angustias Page; Claudio J Conti; Chu-Xia Deng; José L Jorcano; David G Johnson
Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
Oncogene 2003;22(35):5415-26.
2003: Norbert Wikonkál; Eva Remenyik; Dejan Knezevic; Wengeng Zhang; Ming Liu; Hongyu Zhao; Thomas R Berton; David G Johnson; Douglas E Brash
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
Nature cell biology 2003;5(7):655-60.
2002: Robert J Rounbehler; Pamela M Rogers; Claudio J Conti; David G Johnson
Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.
Cancer research 2002;62(11):3276-81.
2002: Jamie L Russell; John T Powers; Robert J Rounbehler; Pamela M Rogers; Claudio J Conti; David G Johnson
ARF differentially modulates apoptosis induced by E2F1 and Myc.
Molecular and cellular biology 2002;22(5):1360-8.
2001: Robert J Rounbehler; Robin Schneider-Broussard; Claudio J Conti; David G Johnson
Myc lacks E2F1's ability to suppress skin carcinogenesis.
Oncogene 2001;20(38):5341-9.
2001: D Wang; J Russell; H Xu; David G Johnson
Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis.
Molecular carcinogenesis 2001;31(2):90-100.
2001: Aijin Wang; David G Johnson; Michael C MacLeod
Molecular cloning and characterization of a novel mouse epidermal differentiation gene and its promoter.
Genomics 2001;73(3):284-90.
2000: D Wang; Jamie L Russell; David G Johnson
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo.
Molecular and cellular biology 2000;20(10):3417-24.
2000: David G Johnson
The paradox of E2F1: oncogene and tumor suppressor gene.
Molecular carcinogenesis 2000;27(3):151-7.
2000: Aijin Wang; Robin Schneider-Broussard; Addanki Kumar; Michael C MacLeod; David G Johnson
Regulation of BRCA1 expression by the Rb-E2F pathway.
The Journal of biological chemistry 2000;275(6):4532-6.
1999: Aijin Wang; A Pierce; K Judson-Kremer; Sally Gaddis; C Marcelo Aldaz; David G Johnson; Michael C MacLeod
Rapid analysis of gene expression (RAGE) facilitates universal expression profiling.
Nucleic acids research 1999;27(23):4609-18.
1999: AM Pierce; Robin Schneider-Broussard; Irma B Gimenez-Conti; Jamie L Russell; Claudio J Conti; David G Johnson
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model.
Molecular and cellular biology 1999;19(9):6408-14.
1998: Marcelo L Rodriguez-Puebla; Margaret LaCava; Irma B Gimenez-Conti; David G Johnson; Claudio J Conti
Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin.
Oncogene 1998;17(17):2251-8.
1998: AM Pierce; Irma B Gimenez-Conti; Robin Schneider-Broussard; Luis A. Martinez; Claudio J Conti; David G Johnson
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8858-63.
1998: AM Pierce; Robin Schneider-Broussard; J L Philhower; David G Johnson
Differential activities of E2F family members: unique functions in regulating transcription.
Molecular carcinogenesis 1998;22(3):190-8.
1998: David G Johnson; Robin Schneider-Broussard
Role of E2F in cell cycle control and cancer.
Frontiers in bioscience : a journal and virtual library 1998;3():d447-8.
1998: AM Pierce; S M Fisher; Claudio J Conti; David G Johnson
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development.
Oncogene 1998;16(10):1267-76.
1998: Marcelo L Rodriguez-Puebla; A I Robles; David G Johnson; Margaret LaCava; Claudio J Conti
Synchronized proliferation induced by 12-O-tetradecanoylphorbol-13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(1):31-9.
1997: David G Johnson; A Coleman; K Leslie Powell; Michael C MacLeod
High-affinity binding of the cell cycle-regulated transcription factors E2F1 and E2F4 to benzo[a]pyrene diol epoxide-DNA adducts.
Molecular carcinogenesis 1997;20(2):216-23.
1997: Andrew Butler; David G Johnson; Addanki Kumar; S Narayan; S H Wilson; Michael C MacLeod
Disruption of transcription in vitro and gene expression in vivo by DNA adducts derived from a benzo[a]pyrene diol epoxide located in heterologous sequences.
Carcinogenesis 1997;18(2):239-44.