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Gary Johnson
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19
Heasley, Lynn
18
Gelfand, Erwin
14
Worthen, Scott
12
Abell, Amy
11
Fanger, Gary
11
Terada, N
11
Widmann, Christian
10
Yujiri, Toshiaki
10
Vaillancourt, Richard
10
Cuevas, Bruce
10
Garrington, Timothy
9
Gerwins, Pär
9
Avdi, Natalie
8
Johnson, Nancy
8
Tyler, Kenneth
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All Publications
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2009: Crose Lisa E S; Hilder Thomas L; Sciaky Noah; Johnson Gary L
Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.
The Journal of biological chemistry 2009;284(20):13301-5.
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2009: Abell Amy N; Granger Deborah A; Johnson Nancy L; Vincent-Jordan Nicole; Dibble Christopher F; Johnson Gary L
Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase.
Molecular and cellular biology 2009;29(10):2748-61.
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2009: Xie Ling; Jing Linhong; Yu Yanbao; Nakamura Kazuhiro; Parker Carol E; Johnson Gary L; Chen Xian
In vivo profiling endogenous interactions with knock-out in mammalian cells.
Analytical chemistry 2009;81(4):1411-7.
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2009: Johnson Gary L; Gomez Shawn M
Sequence patches on MAPK surfaces define protein-protein interactions.
Genome biology 2009;10(6):222.
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2008: Arora P; Cuevas B D; Russo A; Johnson G L; Trejo J
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.
Oncogene 2008;27(32):4434-45.
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2008: Nakamura Kazuhiro; Zawistowski Jon S; Hughes Mark A; Sexton Jonathan Z; Yeh Li-An; Johnson Gary L; Scott John E
Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2008;13(5):396-405.
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2008: Wu Yang; Johnson Gary L; Gomez Shawn M
Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells.
Journal of molecular signaling 2008;3():11.
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2007: Hilder Thomas L; Malone Michael H; Bencharit Sompop; Colicelli John; Haystead Timothy A; Johnson Gary L; Wu Christine C
Proteomic identification of the cerebral cavernous malformation signaling complex.
Journal of proteome research 2007;6(11):4343-55.
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2007: Winter-Vann Ann M; Johnson Gary L
Integrated activation of MAP3Ks balances cell fate in response to stress.
Journal of cellular biochemistry 2007;102(4):848-58.
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2007: Abell Amy N; Granger Deborah A; Johnson Gary L
MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.
The Journal of biological chemistry 2007;282(42):30476-84.
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2007: Johnson Gary L; Nakamura Kazuhiro
The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.
Biochimica et biophysica acta 2007;1773(8):1341-8.
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2007: Nakamura Kazuhiro; Johnson Gary L
Noncanonical function of MEKK2 and MEK5 PB1 domains for coordinated extracellular signal-regulated kinase 5 and c-Jun N-terminal kinase signaling.
Molecular and cellular biology 2007;27(12):4566-77.
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2007: Cuevas B D; Abell A N; Johnson G L
Role of mitogen-activated protein kinase kinase kinases in signal integration.
Oncogene 2007;26(22):3159-71.
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2007: Beltran A; Parikh S; Liu Y; Cuevas B D; Johnson G L; Futscher B W; Blancafort P
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors.
Oncogene 2007;26(19):2791-8.
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2007: Hilder Thomas L; Malone Michael H; Johnson Gary L
Hyperosmotic induction of mitogen-activated protein kinase scaffolding.
Methods in enzymology 2007;428():297-312.
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2007: Malone Michael H; Sciaky Noah; Stalheim Lisa; Hahn Klaus M; Linney Elwood; Johnson Gary L
Laser-scanning velocimetry: a confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae.
BMC biotechnology 2007;7():40.
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2006: Keating A K; Salzberg D B; Sather S; Liang X; Nickoloff S; Anwar A; Deryckere D; Hill K; Joung D; Sawczyn K K; Park J; Curran-Everett D; McGavran L; Meltesen L; Gore L; Johnson G L; Graham D K
Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase.
Oncogene 2006;25(45):6092-100.
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2006: Cuevas B D; Winter-Vann A M; Johnson N L; Johnson G L
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Oncogene 2006;25(36):4998-5010.
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2006: Nakamura Kazuhiro; Uhlik Mark T; Johnson Nancy L; Hahn Klaus M; Johnson Gary L
PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation.
Molecular and cellular biology 2006;26(6):2065-79.
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2005: Stearman Robert S; Dwyer-Nield Lori; Zerbe Laura; Blaine Stacy A; Chan Zeng; Bunn Paul A; Johnson Gary L; Hirsch Fred R; Merrick Daniel T; Franklin Wilbur A; Baron Anna E; Keith Robert L; Nemenoff Raphael A; Malkinson Alvin M; Geraci Mark W
Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model.
The American journal of pathology 2005;167(6):1763-75.
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2005: Abell Amy N; Rivera-Perez Jaime A; Cuevas Bruce D; Uhlik Mark T; Sather Susan; Johnson Nancy L; Minton Suzanne K; Lauder Jean M; Winter-Vann Ann M; Nakamura Kazuhiro; Magnuson Terry; Vaillancourt Richard R; Heasley Lynn E; Johnson Gary L
Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.
Molecular and cellular biology 2005;25(20):8948-59.
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2005: Abell Amy N; Johnson Gary L
MEKK4 is an effector of the embryonic TRAF4 for JNK activation.
The Journal of biological chemistry 2005;280(43):35793-6.
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2005: Zawistowski Jon S; Stalheim Lisa; Uhlik Mark T; Abell Amy N; Ancrile Brooke B; Johnson Gary L; Marchuk Douglas A
CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.
Human molecular genetics 2005;14(17):2521-31.
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2005: Johnson Gary L; Dohlman Henrik G; Graves Lee M
MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression.
Current opinion in chemical biology 2005;9(3):325-31.
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2005: Li Yan; Minamino Tetsuo; Tsukamoto Osamu; Yujiri Toshiaki; Shintani Yasunori; Okada Ken-ichiro; Nagamachi Yoko; Fujita Masashi; Hirata Akio; Sanada Shoji; Asanuma Hiroshi; Takashima Seiji; Hori Masatsugu; Johnson Gary L; Kitakaze Masafumi
Ablation of MEK kinase 1 suppresses intimal hyperplasia by impairing smooth muscle cell migration and urokinase plasminogen activator expression in a mouse blood-flow cessation model.
Circulation 2005;111(13):1672-8.
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2005: Uhlik Mark T; Temple Brenda; Bencharit Sompop; Kimple Adam J; Siderovski David P; Johnson Gary L
Structural and evolutionary division of phosphotyrosine binding (PTB) domains.
Journal of molecular biology 2005;345(1):1-20.
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2005: Cuevas Bruce D; Uhlik Mark T; Garrington Timothy P; Johnson Gary L
MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability.
Oncogene 2005;24(5):801-9.
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2004: Uhlik Mark T; Abell Amy N; Cuevas Bruce D; Nakamura Kazuhiro; Johnson Gary L
Wiring diagrams of MAPK regulation by MEKK1, 2, and 3.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2004;82(6):658-63.
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2004: Clarke Penny; Meintzer Suzanne M; Wang Yibing; Moffitt Lisa A; Richardson-Burns Sarah M; Johnson Gary L; Tyler Kenneth L
JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells.
Journal of virology 2004;78(23):13132-8.
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2004: Anderson Marsha S; Knall Cindy; Thurman Gail; Mann Don; Cusack Nancy; Johnson Gary L; Ambruso Daniel R
CP-64131, an aminobenzazepine with cytokine-like properties, stimulates human neutrophil functions through the p38-MAPK pathway.
Journal of leukocyte biology 2004;76(2):477-83.
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2004: Kesavan Kamala; Lobel-Rice Katherine; Sun Weiyong; Lapadat Razvan; Webb Saiphone; Johnson Gary L; Garrington Timothy P
MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.
Journal of cellular physiology 2004;199(1):140-8.
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2004: Lieber Jonathan G; Webb Saiphone; Suratt Benjamin T; Young Scott K; Johnson Gary L; Keller Gordon M; Worthen G Scott
The in vitro production and characterization of neutrophils from embryonic stem cells.
Blood 2004;103(3):852-9.
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2004: Abell Amy N; DeCathelineau Aimee M; Weed Scott A; Ambruso Daniel R; Riches David W; Johnson Gary L
Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages.
Journal of cell science 2004;117(Pt 2):243-55.
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2003: Uhlik Mark T; Abell Amy N; Johnson Nancy L; Sun Weiyong; Cuevas Bruce D; Lobel-Rice Katherine E; Horne Eric A; Dell'Acqua Mark L; Johnson Gary L
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.
Nature cell biology 2003;5(12):1104-10.
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2003: Wei Xudong; Sun Weiyong; Fan Ruihua; Hahn Joanne; Joetham Anthony; Li Guiming; Webb Saiphone; Garrington Timothy; Dakhama Azzeddine; Lucas Joseph; Johnson Gary L; Gelfand Erwin W
MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells.
European journal of immunology 2003;33(10):2903-9.
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2003: Nakamura Kazuhiro; Johnson Gary L
PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.
The Journal of biological chemistry 2003;278(39):36989-92.
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2003: DeBiasi Roberta L; Clarke Penny; Meintzer Suzanne; Jotte Robert; Kleinschmidt-Demasters B K; Johnson Gary L; Tyler Kenneth L
Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis.
Journal of virology 2003;77(16):8934-47.
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2003: Cuevas Bruce D; Abell Amy N; Witowsky James A; Yujiri Toshiaki; Johnson Nancy Lassignal; Kesavan Kamala; Ware Marti; Jones Peter L; Weed Scott A; DeBiasi Roberta L; Oka Yoshitomo; Tyler Kenneth L; Johnson Gary L
MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.
The EMBO journal 2003;22(13):3346-55.
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2003: Sun Weiyong; Wei Xudong; Kesavan Kamala; Garrington Timothy P; Fan Ruihua; Mei Junjie; Anderson Steven M; Gelfand Erwin W; Johnson Gary L
MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src.
Molecular and cellular biology 2003;23(7):2298-308.
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2003: Witowsky James; Abell Amy; Johnson Nancy Lassignal; Johnson Gary L; Cuevas Bruce D
MEKK1 is required for inducible urokinase-type plasminogen activator expression.
The Journal of biological chemistry 2003;278(8):5941-6.
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2003: Witowsky James A; Johnson Gary L
Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways.
The Journal of biological chemistry 2003;278(3):1403-6.
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2002: Johnson Gary L; Lapadat Razvan
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases.
Science (New York, N.Y.) 2002;298(5600):1911-2.
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2002: Bild Andrea H; Mendoza Francisco J; Gibson Erika M; Huang Mei; Villanueva Jacylyn; Garrington Timothy P; Jove Richard; Johnson Gary L; Gibson Spencer B
MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
Oncogene 2002;21(43):6649-56.
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2002: Kassenbrock C Kenneth; Hunter Seija; Garl Pamela; Johnson Gary L; Anderson Steven M
Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor.
The Journal of biological chemistry 2002;277(28):24967-75.
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2002: Minamino Tetsuo; Yujiri Toshiaki; Terada Naohiro; Taffet George E; Michael Lloyd H; Johnson Gary L; Schneider Michael D
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3866-71.
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2002: Poggioli George J; DeBiasi Roberta L; Bickel Ryan; Jotte Robert; Spalding Aaron; Johnson Gary L; Tyler Kenneth L
Reovirus-induced alterations in gene expression related to cell cycle regulation.
Journal of virology 2002;76(6):2585-94.
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2002: Schlesinger Thomas K; Bonvin Christelle; Jarpe Matthew B; Fanger Gary R; Cardinaux Jean-Rene; Johnson Gary L; Widmann Christian
Apoptosis stimulated by the 91-kDa caspase cleavage MEKK1 fragment requires translocation to soluble cellular compartments.
The Journal of biological chemistry 2002;277(12):10283-91.
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2002: Bonvin Christelle; Guillon Audrey; van Bemmelen Miguel X; Gerwins Pär; Johnson Gary L; Widmann Christian
Role of the amino-terminal domains of MEKKs in the activation of NF kappa B and MAPK pathways and in the regulation of cell proliferation and apoptosis.
Cellular signalling 2002;14(2):123-31.
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2002: Spalding Aaron C; Jotte Robert M; Scheinman Robert I; Geraci Mark W; Clarke Penny; Tyler Kenneth L; Johnson Gary L
TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells.
Oncogene 2002;21(2):260-71.
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2001: Clarke P; Meintzer S M; Widmann C; Johnson G L; Tyler K L
Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun.
Journal of virology 2001;75(23):11275-83.
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2001: Clarke P; Meintzer S M; Spalding A C; Johnson G L; Tyler K L
Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection.
Oncogene 2001;20(47):6910-9.
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2001: Widmann C; Sather S; Oyer R; Johnson G L; Dreskin S C
In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain.
Biochimica et biophysica acta 2001;1547(1):167-73.
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2001: Chayama K; Papst P J; Garrington T P; Pratt J C; Ishizuka T; Webb S; Ganiatsas S; Zon L I; Sun W; Johnson G L; Gelfand E W
Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4599-604.
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2001: Sun W; Kesavan K; Schaefer B C; Garrington T P; Ware M; Johnson N L; Gelfand E W; Johnson G L
MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.
The Journal of biological chemistry 2001;276(7):5093-100.
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2001: Avdi N J; Nick J A; Whitlock B B; Billstrom M A; Henson P M; Johnson G L; Worthen G S
Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway in human neutrophils. Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases apoptosis.
The Journal of biological chemistry 2001;276(3):2189-99.
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2000: Garrington T P; Ishizuka T; Papst P J; Chayama K; Webb S; Yujiri T; Sun W; Sather S; Russell D M; Gibson S B; Keller G; Gelfand E W; Johnson G L
MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells.
The EMBO journal 2000;19(20):5387-95.
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2000: Clarke P; Meintzer S M; Gibson S; Widmann C; Garrington T P; Johnson G L; Tyler K L
Reovirus-induced apoptosis is mediated by TRAIL.
Journal of virology 2000;74(17):8135-9.
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2000: Sun W; Vincent S; Settleman J; Johnson G L
MEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinase.
The Journal of biological chemistry 2000;275(32):24421-8.
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2000: Yujiri T; Ware M; Widmann C; Oyer R; Russell D; Chan E; Zaitsu Y; Clarke P; Tyler K; Oka Y; Fanger G R; Henson P; Johnson G L
MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7272-7.
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2000: Sakata N; Hamelmann E; Siadak A W; Terada N; Gerwins P; Aruffo A; Johnson G L; Gelfand E W
Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes.
Cellular immunology 2000;201(2):109-23.
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2000: Ambruso D R; Knall C; Abell A N; Panepinto J; Kurkchubasche A; Thurman G; Gonzalez-Aller C; Hiester A; deBoer M; Harbeck R J; Oyer R; Johnson G L; Roos D
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4654-9.
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2000: Sakata N; Kawasome H; Terada N; Johnson G L; Gelfand E W
CD40 and adenosine A2 receptor agonist-cyclic adenosine monophosphate rescue B-cell antigen receptor-induced apoptosis through independent pathways and converge to prevent caspase activation.
The Journal of allergy and clinical immunology 2000;105(3):522-31.
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2000: Gibson S B; Oyer R; Spalding A C; Anderson S M; Johnson G L
Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL.
Molecular and cellular biology 2000;20(1):205-12.
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1999: Minamino T; Yujiri T; Papst P J; Chan E D; Johnson G L; Terada N
MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15127-32.
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1999: Schlesinger T K; Demali K A; Johnson G L; Kazlauskas A
Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src.
The Biochemical journal 1999;344 Pt 2():519-26.
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1999: Schaefer B C; Ware M F; Marrack P; Fanger G R; Kappler J W; Johnson G L; Monks C R
Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor.
Immunity 1999;11(4):411-21.
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1999: Sakata N; Kawasome H; Terada N; Gerwins P; Johnson G L; Gelfand E W
Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells.
European journal of immunology 1999;29(9):2999-3008.
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1999: Nick J A; Avdi N J; Young S K; McDonald P P; Billstrom M A; Henson P M; Johnson G L; Worthen G S
An intracellular signaling pathway linking lipopolysaccharide stimulation to cellular responses of the human neutrophil: the p38 MAP kinase cascade and its functional significance.
Chest 1999;116(1 Suppl):54S-55S.
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1999: Gibson S; Tu S; Oyer R; Anderson S M; Johnson G L
Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation.
The Journal of biological chemistry 1999;274(25):17612-8.
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1999: Yujiri T; Fanger G R; Garrington T P; Schlesinger T K; Gibson S; Johnson G L
MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.
The Journal of biological chemistry 1999;274(18):12605-10.
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1999: Garrington T P; Johnson G L
Organization and regulation of mitogen-activated protein kinase signaling pathways.
Current opinion in cell biology 1999;11(2):211-8.
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1999: Gibson S; Widmann C; Johnson G L
Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents.
The Journal of biological chemistry 1999;274(16):10916-22.
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1999: Nick J A; Avdi N J; Young S K; Lehman L A; McDonald P P; Frasch S C; Billstrom M A; Henson P M; Johnson G L; Worthen G S
Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils.
The Journal of clinical investigation 1999;103(6):851-8.
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1999: Ishizuka T; Chayama K; Takeda K; Hamelmann E; Terada N; Keller G M; Johnson G L; Gelfand E W
Mitogen-activated protein kinase activation through Fc epsilon receptor I and stem cell factor receptor is differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2087-94.
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1999: Widmann C; Gibson S; Jarpe M B; Johnson G L
Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human.
Physiological reviews 1999;79(1):143-80.
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1998: Yujiri T; Sather S; Fanger G R; Johnson G L
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption.
Science (New York, N.Y.) 1998;282(5395):1911-4.
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1998: Schlesinger T K; Fanger G R; Yujiri T; Johnson G L
The TAO of MEKK.
Frontiers in bioscience : a journal and virtual library 1998;3():D1181-6.
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1998: McLeish K R; Knall C; Ward R A; Gerwins P; Coxon P Y; Klein J B; Johnson G L
Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSF.
Journal of leukocyte biology 1998;64(4):537-45.
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1998: Ishizuka T; Kawasome H; Terada N; Takeda K; Gerwins P; Keller G M; Johnson G L; Gelfand E W
Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3624-30.
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1998: Jarpe M B; Widmann C; Knall C; Schlesinger T K; Gibson S; Yujiri T; Fanger G R; Gelfand E W; Johnson G L
Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.
Oncogene 1998;17(11 Reviews):1475-82.
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1998: Billstrom M A; Johnson G L; Avdi N J; Worthen G S
Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infection.
Journal of virology 1998;72(7):5535-44.
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1998: Kawasome H; Papst P; Webb S; Keller G M; Johnson G L; Gelfand E W; Terada N
Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):5033-8.
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1998: Widmann C; Gerwins P; Johnson N L; Jarpe M B; Johnson G L
MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.
Molecular and cellular biology 1998;18(4):2416-29.
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1998: Widmann C; Gibson S; Johnson G L
Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals.
The Journal of biological chemistry 1998;273(12):7141-7.
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1998: Fanger G R; Widmann C; Porter A C; Sather S; Johnson G L; Vaillancourt R R
14-3-3 proteins interact with specific MEK kinases.
The Journal of biological chemistry 1998;273(6):3476-83.
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1998: Jarpe M B; Knall C; Mitchell F M; Buhl A M; Duzic E; Johnson G L
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P acts as a biased agonist toward neuropeptide and chemokine receptors.
The Journal of biological chemistry 1998;273(5):3097-104.
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1998: Knall C; Johnson G L
G-protein regulatory pathways: rocketing into the twenty-first century.
Journal of cellular biochemistry. Supplement 1998;30-31():137-46.
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1997: Widmann C; Johnson N L; Gardner A M; Smith R J; Johnson G L
Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.
Oncogene 1997;15(20):2439-47.
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1997: Winston B W; Chan E D; Johnson G L; Riches D W
Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4491-7.
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1997: Fanger G R; Johnson N L; Johnson G L
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42.
The EMBO journal 1997;16(16):4961-72.
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1997: Ishizuka T; Terada N; Gerwins P; Hamelmann E; Oshiba A; Fanger G R; Johnson G L; Gelfand E W
Mast cell tumor necrosis factor alpha production is regulated by MEK kinases.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6358-63.
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1997: Rose D M; Winston B W; Chan E D; Riches D W; Gerwins P; Johnson G L; Henson P M
Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3433-8.
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1997: Knall C; Worthen G S; Johnson G L
Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3052-7.
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1997: Gerwins P; Blank J L; Johnson G L
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway.
The Journal of biological chemistry 1997;272(13):8288-95.
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1997: Nick J A; Avdi N J; Young S K; Knall C; Gerwins P; Johnson G L; Worthen G S
Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.
The Journal of clinical investigation 1997;99(5):975-86.
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1997: Ishizuka T; Sakata N; Johnson G L; Gelfand E W; Terada N
Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells.
Biochemical and biophysical research communications 1997;230(2):386-91.
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1997: Fanger G R; Vaillancourt R R; Heasley L E; Montmayeur J P; Johnson G L; Maue R A
Analysis of mutant platelet-derived growth factor receptors expressed in PC12 cells identifies signals governing sodium channel induction during neuronal differentiation.
Molecular and cellular biology 1997;17(1):89-99.
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1996: Avdi N J; Winston B W; Russel M; Young S K; Johnson G L; Worthen G S
Activation of MEKK by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Mapping pathways for mitogen-activated protein kinase activation.
The Journal of biological chemistry 1996;271(52):33598-606.
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1996: Vaillancourt R R; Gardner A M; Kazlauskas A; Johnson G L
The kinase-inactive PDGF beta-receptor mediates activation of the MAP kinase cascade via the endogenous PDGF alpha-receptor in HepG2 cells.
Oncogene 1996;13(1):151-9.
-
1996: Gardner A M; Johnson G L
Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase.
The Journal of biological chemistry 1996;271(24):14560-6.
-
1996: Nick J A; Avdi N J; Gerwins P; Johnson G L; Worthen G S
Activation of a p38 mitogen-activated protein kinase in human neutrophils by lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4867-75.
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1996: Ishizuka T; Oshiba A; Sakata N; Terada N; Johnson G L; Gelfand E W
Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin.
The Journal of biological chemistry 1996;271(22):12762-6.
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1996: Blank J L; Gerwins P; Elliott E M; Sather S; Johnson G L
Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.
The Journal of biological chemistry 1996;271(10):5361-8.
-
1996: Johnson N L; Gardner A M; Diener K M; Lange-Carter C A; Gleavy J; Jarpe M B; Minden A; Karin M; Zon L I; Johnson G L
Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death.
The Journal of biological chemistry 1996;271(6):3229-37.
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1996: Knall C; Young S; Nick J A; Buhl A M; Worthen G S; Johnson G L
Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils.
The Journal of biological chemistry 1996;271(5):2832-8.
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1996: Heasley L E; Zamarripa J; Storey B; Helfrich B; Mitchell F M; Bunn P A; Johnson G L
Discordant signal transduction and growth inhibition of small cell lung carcinomas induced by expression of GTPase-deficient G alpha 16.
The Journal of biological chemistry 1996;271(1):349-54.
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1995: Sakata N; Patel H R; Terada N; Aruffo A; Johnson G L; Gelfand E W
Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells.
The Journal of biological chemistry 1995;270(51):30823-8.
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1995: Buhl A M; Johnson N L; Dhanasekaran N; Johnson G L
G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly.
The Journal of biological chemistry 1995;270(42):24631-4.
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1995: Knall C; Worthen G S; Buhl A M; Johnson G L
IL-8 signal transduction in human neutrophils.
Annals of the New York Academy of Sciences 1995;766():288-91.
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1995: Buhl A M; Osawa S; Johnson G L
Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor.
The Journal of biological chemistry 1995;270(34):19828-32.
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1995: Mitchell F M; Russell M; Johnson G L
Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells.
The Biochemical journal 1995;309 ( Pt 2)():381-4.
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1995: Vaillancourt R R; Heasley L E; Zamarripa J; Storey B; Valius M; Kazlauskas A; Johnson G L
Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.
Molecular and cellular biology 1995;15(7):3644-53.
-
1995: Russell M; Lange-Carter C A; Johnson G L
Regulation of recombinant MEK1 and MEK2b expressed in Escherichia coli.
Biochemistry 1995;34(20):6611-5.
-
1995: Russell M; Lange-Carter C A; Johnson G L
Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).
The Journal of biological chemistry 1995;270(20):11757-60.
-
1995: Lin A; Minden A; Martinetto H; Claret F X; Lange-Carter C; Mercurio F; Johnson G L; Karin M
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2.
Science (New York, N.Y.) 1995;268(5208):286-90.
-
1995: Mitchell F M; Heasley L E; Qian N X; Zamarripa J; Johnson G L
Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P.
The Journal of biological chemistry 1995;270(15):8623-8.
-
1995: Winston B W; Lange-Carter C A; Gardner A M; Johnson G L; Riches D W
Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1614-8.
-
1995: Qian N X; Russell M; Johnson G L
Acetylcholine muscarinic receptor regulation of the Ras/Raf/MAP kinase pathway.
Life sciences 1995;56(11-12):945-9.
-
1995: Lange-Carter C A; Johnson G L
Assay of MEK kinases.
Methods in enzymology 1995;255():290-301.
-
1994: Minden A; Lin A; McMahon M; Lange-Carter C; Dérijard B; Davis R J; Johnson G L; Karin M
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK.
Science (New York, N.Y.) 1994;266(5191):1719-23.
-
1994: Vaillancourt R R; Gardner A M; Johnson G L
B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.
Molecular and cellular biology 1994;14(10):6522-30.
-
1994: Goldman F; Jensen W A; Johnson G L; Heasley L; Cambier J C
gp120 ligation of CD4 induces p56lck activation and TCR desensitization independent of TCR tyrosine phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):2905-17.
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1994: Buhl A M; Avdi N; Worthen G S; Johnson G L
Mapping of the C5a receptor signal transduction network in human neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9190-4.
-
1994: Lange-Carter C A; Johnson G L
Ras-dependent growth factor regulation of MEK kinase in PC12 cells.
Science (New York, N.Y.) 1994;265(5177):1458-61.
-
1994: Worthen G S; Avdi N; Buhl A M; Suzuki N; Johnson G L
FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase.
The Journal of clinical investigation 1994;94(2):815-23.
-
1994: Qian N X; Russell M; Buhl A M; Johnson G L
Expression of GTPase-deficient G alpha 16 inhibits Swiss 3T3 cell growth.
The Journal of biological chemistry 1994;269(26):17417-23.
-
1994: Blumer K J; Johnson G L
Diversity in function and regulation of MAP kinase pathways.
Trends in biochemical sciences 1994;19(6):236-40.
-
1994: Blumer K J; Johnson G L; Lange-Carter C A
Mammalian mitogen-activated protein kinase kinase kinase (MEKK) can function in a yeast mitogen-activated protein kinase pathway downstream of protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4925-9.
-
1994: Franklin R A; Tordai A; Patel H; Gardner A M; Johnson G L; Gelfand E W
Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes.
The Journal of clinical investigation 1994;93(5):2134-40.
-
1994: Russell M; Winitz S; Johnson G L
Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity.
Molecular and cellular biology 1994;14(4):2343-51.
-
1994: Johnson G L; Vaillancourt R R
Sequential protein kinase reactions controlling cell growth and differentiation.
Current opinion in cell biology 1994;6(2):230-8.
-
1994: Johnson G L; Gardner A M; Lange-Carter C; Qian N X; Russell M; Winitz S
How does the G protein, Gi2, transduce mitogenic signals?
Journal of cellular biochemistry 1994;54(4):415-22.
-
1994: Tordai A; Franklin R A; Patel H; Gardner A M; Johnson G L; Gelfand E W
Cross-linking of surface IgM stimulates the Ras/Raf-1/MEK/MAPK cascade in human B lymphocytes.
The Journal of biological chemistry 1994;269(10):7538-43.
-
1994: Conrad K E; Oberwetter J M; Vaillancourt R; Johnson G L; Gutierrez-Hartmann A
Identification of the functional components of the Ras signaling pathway regulating pituitary cell-specific gene expression.
Molecular and cellular biology 1994;14(3):1553-65.
-
1994: Gardner A M; Vaillancourt R R; Lange-Carter C A; Johnson G L
MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.
Molecular biology of the cell 1994;5(2):193-201.
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1994: Winitz S; Gupta S K; Qian N X; Heasley L E; Nemenoff R A; Johnson G L
Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation.
The Journal of biological chemistry 1994;269(3):1889-95.
-
1994: Lange-Carter C A; Pleiman C; Johnson G L
A novel upstream activator in the mitogen-activated protein kinase signal transduction pathway.
Recent progress in hormone research 1994;49():341-5.
-
1994: Winitz S; Russell M; Johnson G L
Construction of mutant and chimeric G-protein alpha subunits.
Methods in enzymology 1994;237():321-6.
-
1994: Gardner A M; Lange-Carter C A; Vaillancourt R R; Johnson G L
Measuring activation of kinases in mitogen-activated protein kinase regulatory network.
Methods in enzymology 1994;238():258-70.
-
1993: Winitz S; Russell M; Qian N X; Gardner A; Dwyer L; Johnson G L
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.
The Journal of biological chemistry 1993;268(26):19196-9.
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1993: Pleiman C M; Clark M R; Gauen L K; Winitz S; Coggeshall K M; Johnson G L; Shaw A S; Cambier J C
Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase.
Molecular and cellular biology 1993;13(9):5877-87.
-
1993: Russell M; Johnson G L
G protein amino-terminal alpha i2/alpha s chimeras reveal amino acids important in regulating alpha s activity.
Molecular pharmacology 1993;44(2):255-63.
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1993: Gardner A M; Vaillancourt R R; Johnson G L
Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins.
The Journal of biological chemistry 1993;268(24):17896-901.
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1993: Senkfor S I; Johnson G L; Berl T
A molecular map of G protein alpha chains in microdissected rat nephron segments.
The Journal of clinical investigation 1993;92(2):786-90.
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1993: Buhl A M; Eisfelder B J; Worthen G S; Johnson G L; Russell M
Selective coupling of the human anaphylatoxin C5a receptor and alpha 16 in human kidney 293 cells.
FEBS letters 1993;323(1-2):132-4.
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1993: Wadzinski B E; Wheat W H; Jaspers S; Peruski L F; Lickteig R L; Johnson G L; Klemm D J
Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.
Molecular and cellular biology 1993;13(5):2822-34.
-
1993: Qian N X; Winitz S; Johnson G L
Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4077-81.
-
1993: Lange-Carter C A; Pleiman C M; Gardner A M; Blumer K J; Johnson G L
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf.
Science (New York, N.Y.) 1993;260(5106):315-9.
-
1993: Nemenoff R A; Winitz S; Qian N X; Van Putten V; Johnson G L; Heasley L E
Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.
The Journal of biological chemistry 1993;268(3):1960-4.
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1992: Abdel-Hafiz H A; Heasley L E; Kyriakis J M; Avruch J; Kroll D J; Johnson G L; Hoeffler J P
Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2079-89.
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1992: Gallego C; Gupta S K; Winitz S; Eisfelder B J; Johnson G L
Myristoylation of the G alpha i2 polypeptide, a G protein alpha subunit, is required for its signaling and transformation functions.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9695-9.
-
1992: Wadzinski B E; Eisfelder B J; Peruski L F; Mumby M C; Johnson G L
NH2-terminal modification of the phosphatase 2A catalytic subunit allows functional expression in mammalian cells.
The Journal of biological chemistry 1992;267(24):16883-8.
-
1992: Gallego C; Gupta S K; Heasley L E; Qian N X; Johnson G L
Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7355-9.
-
1992: Heasley L E; Johnson G L
The beta-PDGF receptor induces neuronal differentiation of PC12 cells.
Molecular biology of the cell 1992;3(5):545-53.
-
1992: Gupta S K; Gallego C; Johnson G L; Heasley L E
MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts.
The Journal of biological chemistry 1992;267(12):7987-90.
-
1992: Gupta S K; Gallego C; Lowndes J M; Pleiman C M; Sable C; Eisfelder B J; Johnson G L
Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes.
Molecular and cellular biology 1992;12(1):190-7.
-
1992: Gupta S K; Gallego C; Johnson G L
Mitogenic pathways regulated by G protein oncogenes.
Molecular biology of the cell 1992;3(1):123-8.
-
1991: Dhanasekaran N; Osawa S; Johnson G L
The NH2-terminal alpha subunit attenuator domain confers regulation of G protein activation by beta gamma complexes.
Journal of cellular biochemistry 1991;47(4):352-8.
-
1991: Gupta S K; Dhanasekaran N; Heasley L E; Johnson G L
Activating mutations in the NH2- and COOH-terminal moieties of the Gs alpha subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation.
Journal of cellular biochemistry 1991;47(4):359-68.
-
1991: Johnson G L; Dhanasekaran N; Gupta S K; Lowndes J M; Vaillancourt R R; Ruoho A E
Genetic and structural analysis of G protein alpha subunit regulatory domains.
Journal of cellular biochemistry 1991;47(2):136-46.
-
1991: Lowndes J M; Gupta S K; Osawa S; Johnson G L
GTPase-deficient G alpha i2 oncogene gip2 inhibits adenylylcyclase and attenuates receptor-stimulated phospholipase A2 activity.
The Journal of biological chemistry 1991;266(22):14193-7.
-
1991: Osawa S; Johnson G L
A dominant negative G alpha s mutant is rescued by secondary mutation of the alpha chain amino terminus.
The Journal of biological chemistry 1991;266(8):4673-6.
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1990: Wadzinski B E; Heasley L E; Johnson G L
Multiplicity of protein serine-threonine phosphatases in PC12 pheochromocytoma and FTO-2B hepatoma cells.
The Journal of biological chemistry 1990;265(35):21504-8.
-
1990: Osawa S; Dhanasekaran N; Woon C W; Johnson G L
G alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit complex interactions.
Cell 1990;63(4):697-706.
-
1990: Gupta S K; Diez E; Heasley L E; Osawa S; Johnson G L
A G protein mutant that inhibits thrombin and purinergic receptor activation of phospholipase A2.
Science (New York, N.Y.) 1990;249(4969):662-6.
-
1990: Osawa S; Heasley L E; Dhanasekaran N; Gupta S K; Woon C W; Berlot C; Johnson G L
Mutation of the Gs protein alpha subunit NH2 terminus relieves an attenuator function, resulting in constitutive adenylyl cyclase stimulation.
Molecular and cellular biology 1990;10(6):2931-40.
-
1990: Vaillancourt R R; Dhanasekaran N; Johnson G L; Ruoho A E
2-Azido-[32P]NAD+, a photoactivatable probe for G-protein structure: evidence for holotransducin oligomers in which the ADP-ribosylated carboxyl terminus of alpha interacts with both alpha and gamma subunits.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3645-9.
-
1990: Kelleher D J; Johnson G L
Characterization of rhodopsin kinase purified from bovine rod outer segments.
The Journal of biological chemistry 1990;265(5):2632-9.
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1990: Weiss E R; Heller-Harrison R A; Diez E; Crasnier M; Malbon C C; Johnson G L
Rhodopsin expressed in Chinese hamster ovary cells regulates adenylyl cyclase activity.
Journal of molecular endocrinology 1990;4(1):71-9.
-
1990: Heasley L E; Dhanasekaran N; Gupta S K; Osawa S; Johnson G L
Chimeras of the Gs alpha subunit that had the NH2- or COOH-terminal sequence substituted for the corresponding region of the Gi alpha subunit constitutively activate adenylyl cyclase.
Society of General Physiologists series 1990;45():117-24.
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1989: Johnson G L; Dhanasekaran N
The G-protein family and their interaction with receptors.
Endocrine reviews 1989;10(3):317-31.
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1989: Heasley L E; Johnson G L
Regulation of protein kinase C by nerve growth factor, epidermal growth factor, and phorbol esters in PC12 pheochromocytoma cells.
The Journal of biological chemistry 1989;264(15):8646-52.
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1989: Woon C W; Heasley L; Osawa S; Johnson G L
Mutation of glycine 49 to valine in the alpha subunit of GS results in the constitutive elevation of cyclic AMP synthesis.
Biochemistry 1989;28(11):4547-51.
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1989: Woon C W; Soparkar S; Heasley L; Johnson G L
Expression of a G alpha s/G alpha i chimera that constitutively activates cyclic AMP synthesis.
The Journal of biological chemistry 1989;264(10):5687-93.
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1989: Heasley L E; Johnson G L
Detection of nerve growth factor and epidermal growth factor-regulated protein kinases in PC12 cells with synthetic peptide substrates.
Molecular pharmacology 1989;35(3):331-8.
-
1989: Wessling-Resnick M; Johnson G L
Evidence for oligomeric forms of transducins alpha subunit: formation of intermolecular alpha-alpha disulfide linkages.
Biochemical and biophysical research communications 1989;159(2):651-7.
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1989: Jaspers S R; Rulfs J; Johnson G L; Mole J E; Miller T B
Amino-terminal sequence analysis of rat heart and muscle glycogen synthase: homology to the rabbit enzyme and the implications for hormonal control.
Archives of biochemistry and biophysics 1989;268(2):630-6.
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1988: Dhanasekaran N; Wessling-Resnick M; Kelleher D J; Johnson G L; Ruoho A E
Mapping of the carboxyl terminus within the tertiary structure of transducin's alpha subunit using the heterobifunctional cross-linking reagent, 125I-N-(3-iodo-4-azidophenylpropionamido-S-(2-thiopyridyl) cysteine.
The Journal of biological chemistry 1988;263(34):17942-50.
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1988: Weiss E R; Kelleher D J; Woon C W; Soparkar S; Osawa S; Heasley L E; Johnson G L
Receptor activation of G proteins.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(13):2841-8.
-
1988: Kelleher D J; Johnson G L
Transducin inhibition of light-dependent rhodopsin phosphorylation: evidence for beta gamma subunit interaction with rhodopsin.
Molecular pharmacology 1988;34(4):452-60.
-
1988: Arino J; Woon C W; Brautigan D L; Miller T B; Johnson G L
Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4252-6.
-
1988: Weiss E R; Kelleher D J; Johnson G L
Mapping sites of interaction between rhodopsin and transducin using rhodopsin antipeptide antibodies.
The Journal of biological chemistry 1988;263(13):6150-4.
-
1987: Johnson G L; Brautigan D L; Shriner C; Jaspers S; Arino J; Mole J E; Miller T B; Mumby M C
Sequence homologies between type 1 and type 2A protein phosphatases.
Molecular endocrinology (Baltimore, Md.) 1987;1(10):745-8.
-
1987: Wessling-Resnick M; Johnson G L
Kinetic and hydrodynamic properties of transducin: comparison of physical and structural parameters for GTP-binding regulatory proteins.
Biochemistry 1987;26(14):4316-23.
-
1987: Wolleben C D; McPherson R K; Rulfs J; Johnson G L; Miller T B
Phosphorylation of rat heart glycogen synthase: studies in cardiomyocytes and in vitro phosphorylations with cAMP-dependent kinase and protein phosphatase-1.
Biochimica et biophysica acta 1987;928(1):98-106.
-
1986: Davis R J; Johnson G L; Kelleher D J; Anderson J K; Mole J E; Czech M P
Identification of serine 24 as the unique site on the transferrin receptor phosphorylated by protein kinase C.
The Journal of biological chemistry 1986;261(19):9034-41.
-
1985: Rulfs J; Wolleben C D; Miller T B; Johnson G L
Immunologic identification of a glycogen synthase 93,000-dalton subunit from rat heart and liver.
The Journal of biological chemistry 1985;260(2):1203-7.
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1984: Kelleher D J; Pessin J E; Ruoho A E; Johnson G L
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4316-20.
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1983: Kelleher D J; Rashidbaigi A; Ruoho A E; Johnson G L
Rapid vesicle reconstitution of alprenolol-Sepharose-purified beta 1-adrenergic receptors. Interaction of the purified receptor with N.
The Journal of biological chemistry 1983;258(21):12881-5.
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