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Keith Johnson

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Chemicals & Drugs

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Kristen E Johnson; Keith R Johnson; Parul Katoch; LS Kelsey; Shalini Mitra; Parmender P Mehta
Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells.
Nina V Chaika; Teklab Gebregiworgis; Michael A Hollingsworth; Keith R Johnson; Michelle E Lewallen; Xiang Liu; Kamiya Mehla; Robert Powers; Vinee Purohit; Prakash Radhakrishnan; Roger B Brown; Thomas Caffrey; Fang Yu; Bo Zhang; Pankaj K Singh
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
Nina V Chaika; Dominick DiMaio; Michael A Hollingsworth; Keith R Johnson; Audrey J Lazenby; Kamiya Mehla; Vinee Purohit; Jen Jen Yeh; Fang Yu; Judy M Anderson; Pankaj K Singh
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma.

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2013: Kristen E Johnson; Keith R Johnson; Parul Katoch; LS Kelsey; Shalini Mitra; Parmender P Mehta
Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells.
Molecular biology of the cell 2013;24(6):715-33.
2012: Nina V Chaika; Teklab Gebregiworgis; Michael A Hollingsworth; Keith R Johnson; Michelle E Lewallen; Xiang Liu; Kamiya Mehla; Robert Powers; Vinee Purohit; Prakash Radhakrishnan; Roger B Brown; Thomas Caffrey; Fang Yu; Bo Zhang; Pankaj K Singh
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13787-92.
2012: Nina V Chaika; Dominick DiMaio; Michael A Hollingsworth; Keith R Johnson; Audrey J Lazenby; Kamiya Mehla; Vinee Purohit; Jen Jen Yeh; Fang Yu; Judy M Anderson; Pankaj K Singh
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma.
PloS one 2012;7(3):e32996.
2011: Brett J Roberts; Keith R Johnson; Anjeza Pashaj; James K Wahl
Desmosome dynamics in migrating epithelial cells requires the actin cytoskeleton.
Experimental cell research 2011;317(20):2814-22.
2010: Rajgopal Govindarajan; Souvik Chakraborty; Kristen E Johnson; Matthias M Falk; Margaret J Wheelock; Keith R Johnson; Parmender P Mehta
Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells.
Molecular biology of the cell 2010;21(23):4089-107.
2010: Souvik Chakraborty; Shalini Mitra; Matthias M Falk; Steve H Caplan; Margaret J Wheelock; Keith R Johnson; Parmender P Mehta
E-cadherin differentially regulates the assembly of Connexin43 and Connexin32 into gap junctions in human squamous carcinoma cells.
The Journal of biological chemistry 2010;285(14):10761-76.
2009: Yoshitaka Fukunaga; Robert A Svoboda; Ronald L Cerny; Keith R Johnson; Margaret J Wheelock
Expression artifact with retroviral vectors based on pBMN.
Analytical biochemistry 2009;395(1):49-53.
2008: Shyamali Mandal; Keith R Johnson; Margaret J Wheelock
TGF-beta induces formation of F-actin cores and matrix degradation in human breast cancer cells via distinct signaling pathways.
Experimental cell research 2008;314(19):3478-93.
2008: Sarah A Keim; Keith R Johnson; Margaret J Wheelock; James K Wahl
Generation and characterization of monoclonal antibodies against the proregion of human desmoglein-2.
Hybridoma (2005) 2008;27(4):249-58.
2008: Yasushi Shintani; Yuri Fukumoto; Nina Chaika; Robert Svoboda; Margaret J Wheelock; Keith R Johnson
Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1.
The Journal of cell biology 2008;180(6):1277-89.
2008: Margaret J Wheelock; Yasushi Shintani; Masato Maeda; Yuri Fukumoto; Keith R Johnson
Cadherin switching.
Journal of cell science 2008;121(Pt 6):727-35.
2008: Yasushi Shintani; Yuri Fukumoto; Nina Chaika; Paul M Grandgenett; Michael A Hollingsworth; Margaret J Wheelock; Keith R Johnson
ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression.
International journal of cancer. Journal international du cancer 2008;122(1):71-7.
2008: Yuri Fukumoto; Yasushi Shintani; Albert B Reynolds; Keith R Johnson; Margaret J Wheelock
The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane.
Experimental cell research 2008;314(1):52-67.
2008: Yasushi Shintani; Masato Maeda; Nina Chaika; Keith R Johnson; Margaret J Wheelock
Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.
American journal of respiratory cell and molecular biology 2008;38(1):95-104.
2007: Christopher S Theisen; James K Wahl; Keith R Johnson; Margaret J Wheelock
NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility.
Molecular biology of the cell 2007;18(4):1220-32.
2007: Matthew W Curtis; Quan P Ly; Margaret J Wheelock; Keith R Johnson
Evidence that the V832M E-cadherin germ-line missense mutation does not influence the affinity of alpha -catenin for the cadherin/catenin complex.
Cell communication & adhesion 2007;14(2-3):45-55.
2006: Yasushi Shintani; Michael A Hollingsworth; Margaret J Wheelock; Keith R Johnson
Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression.
Cancer research 2006;66(24):11745-53.
2006: M Maeda; E Johnson; S H Mandal; K R Lawson; S A Keim; R A Svoboda; Steve Caplan; James K Wahl; Margaret J Wheelock; Keith R Johnson
Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn).
Oncogene 2006;25(33):4595-604.
2006: Yasushi Shintani; Margaret J Wheelock; Keith R Johnson
Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.
Molecular biology of the cell 2006;17(7):2963-75.
2006: Masato Maeda; Yasushi Shintani; Margaret J Wheelock; Keith R Johnson
Src activation is not necessary for transforming growth factor (TGF)-beta-mediated epithelial to mesenchymal transitions (EMT) in mammary epithelial cells. PP1 directly inhibits TGF-beta receptors I and II.
The Journal of biological chemistry 2006;281(1):59-68.
2005: Young J Kim; Christa Sauer; Karla Testa; James K Wahl; Robert A Svoboda; Keith R Johnson; Margaret J Wheelock; Karen A Knudsen
Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.
Journal of cell science 2005;118(Pt 17):3883-94.
2005: Karen A Knudsen; Christa Sauer; Keith R Johnson; Margaret J Wheelock
Effect of N-cadherin misexpression by the mammary epithelium in mice.
Journal of cellular biochemistry 2005;95(6):1093-107.
2005: Masato Maeda; Keith R Johnson; SHYAMALI MANDAL
Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition.
Journal of cell science 2005;118(Pt 5):873-87.
2005: Meena Jaggi; Prema S Rao; David J Smith; Margaret J Wheelock; Keith R Johnson; George P Hemstreet; Kethandapatti C Balaji
E-cadherin phosphorylation by protein kinase D1/protein kinase C{mu} is associated with altered cellular aggregation and motility in prostate cancer.
Cancer research 2005;65(2):483-92.
2005: Young J Kim; Keith R Johnson; Margaret J Wheelock
N-cadherin-mediated cell motility requires cis dimers.
Cell communication & adhesion 2005;12(1-2):23-39.
2004: Emhonta Johnson; Christopher S Theisen; Keith R Johnson; Margaret J Wheelock
R-cadherin influences cell motility via Rho family GTPases.
The Journal of biological chemistry 2004;279(30):31041-9.
2003: Margaret J Wheelock; Keith R Johnson
Cadherin-mediated cellular signaling.
Current opinion in cell biology 2003;15(5):509-14.
2003: Yunfei Wen; Thomas Caffrey; Margaret J Wheelock; Keith R Johnson; Michael A Hollingsworth
Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.
The Journal of biological chemistry 2003;278(39):38029-39.
2003: Bryan J Katafiasz; Marvin T Nieman; Margaret J Wheelock; Keith R Johnson
Characterization of cadherin-24, a novel alternatively spliced type II cadherin.
The Journal of biological chemistry 2003;278(30):27513-9.
2003: James K Wahl; Young J Kim; Janet M Cullen; Keith R Johnson; Margaret J Wheelock
N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.
The Journal of biological chemistry 2003;278(19):17269-76.
2003: Margaret J Wheelock; Keith R Johnson
Cadherins as modulators of cellular phenotype.
Annual review of cell and developmental biology 2003;19():207-35.
2002: Rajgopal Govindarajan; Sumin Zhao; Xiao-Hong Song; Rong-Jun Guo; Margaret J Wheelock; Keith R Johnson; Parmender P Mehta
Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its mitigation by alpha-catenin.
The Journal of biological chemistry 2002;277(51):50087-97.
2002: Meena Jaggi; Margaret J Wheelock; Keith R Johnson
Differential displacement of classical cadherins by VE-cadherin.
Cell communication & adhesion 2002;9(2):103-15.
2000: J B Kim; S Islam; Y J Kim; R S Prudoff; K M Sass; Margaret J Wheelock; Keith R Johnson
N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility.
The Journal of cell biology 2000;151(6):1193-206.
2000: J E Nieset; Paula Bubulya; T M Sadler; Keith R Johnson; Margaret J Wheelock
The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.
Journal of cell science 2000;113 ( Pt 10)():1737-45.
2000: S Islam; J B Kim; Jill A Trendel; Margaret J Wheelock; Keith R Johnson
Vimentin expression in human squamous carcinoma cells: relationship with phenotypic changes and cadherin-based cell adhesion.
Journal of cellular biochemistry 2000;78(1):141-50.
1999: Marvin T Nieman; R S Prudoff; Keith R Johnson; Margaret J Wheelock
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression.
The Journal of cell biology 1999;147(3):631-44.
1999: F Jin; Albert B Reynolds; M D Hines; Pamela J Jensen; Keith R Johnson; Margaret J Wheelock
Src induces morphological changes in A431 cells that resemble epidermal differentiation through an SH3- and Ras-independent pathway.
Journal of cell science 1999;112 ( Pt 17)():2913-24.
1999: Marvin T Nieman; J B Kim; Keith R Johnson; Margaret J Wheelock
Mechanism of extracellular domain-deleted dominant negative cadherins.
Journal of cell science 1999;112 ( Pt 10)():1621-32.
1997: J E Nieset; A R Redfield; F Jin; Karen A Knudsen; Keith R Johnson; Margaret J Wheelock
Characterization of the interactions of alpha-catenin with alpha-actinin and beta-catenin/plakoglobin.
Journal of cell science 1997;110 ( Pt 8)():1013-22.
1997: Keith R Johnson; William C Merrick; Wendy L Zoll; Y Zhu
Identification of cDNA clones for the large subunit of eukaryotic translation initiation factor 3. Comparison of homologues from human, Nicotiana tabacum, Caenorhabditis elegans, and Saccharomyces cerevisiae.
The Journal of biological chemistry 1997;272(11):7106-13.
1997: J E Lewis; James K Wahl; K M Sass; Pamela J Jensen; Keith R Johnson; Margaret J Wheelock
Cross-talk between adherens junctions and desmosomes depends on plakoglobin.
The Journal of cell biology 1997;136(4):919-34.
1996: S Islam; Thomas Carey; Gregory T Wolf; Margaret J Wheelock; Keith R Johnson
Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.
The Journal of cell biology 1996;135(6 Pt 1):1643-54.
1996: J K Wahl; Paula Bubulya; T M McGranahan-Sadler; L M Sauppé; Margaret J Wheelock; Keith R Johnson
Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: identification of unique and shared domains.
Journal of cell science 1996;109 ( Pt 5)():1143-54.
1995: Alejandro Peralta Soler; Karen A Knudsen; M C Jaurand; Keith R Johnson; Margaret J Wheelock; Andres Klein-Szanto; H Salazar
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Human pathology 1995;26(12):1363-9.
1995: Paula Bubulya; T M McGranahan; Margaret J Wheelock; Keith R Johnson
Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin.
The Journal of biological chemistry 1995;270(34):20201-6.
1995: Karen A Knudsen; Alejandro Peralta Soler; Keith R Johnson; Margaret J Wheelock
Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin.
The Journal of cell biology 1995;130(1):67-77.
1994: J E Lewis; Pamela J Jensen; Keith R Johnson; Margaret J Wheelock
E-cadherin mediates adherens junction organization through protein kinase C.
Journal of cell science 1994;107 ( Pt 12)():3615-21.
1993: E Duran; Richard W Komuniecki; Patricia R Komuniecki; Margaret J Wheelock; Michele Klingbeil; Y C Ma; Keith R Johnson
Characterization of cDNA clones for the 2-methyl branched-chain enoyl-CoA reductase. An enzyme involved in branched-chain fatty acid synthesis in anaerobic mitochondria of the parasitic nematode Ascaris suum.
The Journal of biological chemistry 1993;268(30):22391-6.
1993: Alejandro Peralta Soler; Keith R Johnson; Margaret J Wheelock; Karen A Knudsen
Rhabdomyosarcoma-derived cell lines exhibit aberrant expression of the cell-cell adhesion molecules N-CAM, N-cadherin, and cadherin-associated proteins.
Experimental cell research 1993;208(1):84-93.
1993: Keith R Johnson; J E Lewis; D Li; J Wahl; A P Soler; Karen A Knudsen; Margaret J Wheelock
P- and E-cadherin are in separate complexes in cells expressing both cadherins.
Experimental cell research 1993;207(2):252-60.
1992: Keith R Johnson; Richard W Komuniecki; Y Sun; Margaret J Wheelock
Characterization of cDNA clones for the alpha subunit of pyruvate dehydrogenase from Ascaris suum.
Molecular and biochemical parasitology 1992;51(1):37-47.
1991: Margaret J Wheelock; Richard W Komuniecki; E Duran; Keith R Johnson
Characterization of cDNA clones for the beta subunit of pyruvate dehydrogenase from Ascaris suum.
Molecular and biochemical parasitology 1991;45(1):9-17.