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Tyler Johnson

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Tyler A Johnson; Leonard F Bjeldanes; Wayne D Inman; Johann Sohn; Keith Rayburn
Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders.
Tyler A Johnson; Johann Sohn; Karen Tenney; Frederick A Valeriote; Yvette M Vaske; Helene C Vervoort; Kimberly N White; Leonard F Bjeldanes; Tanya L Cohen; Phillip Crews
Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries.
Frederick A Valeriote; Taro Amagata; Matthew Edelstein; Tyler A Johnson; Joseph Media; Halina Pietraszkiewicz; Karen Tenney; Phillip Crews
Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program.

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All Publications

2013: Tyler A Johnson; Leonard F Bjeldanes; Wayne D Inman; Johann Sohn; Keith Rayburn
Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2013;20(2):143-7.
2012: Tyler A Johnson; Johann Sohn; Karen Tenney; Frederick A Valeriote; Yvette M Vaske; Helene C Vervoort; Kimberly N White; Leonard F Bjeldanes; Tanya L Cohen; Phillip Crews
Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries.
Bioorganic & medicinal chemistry 2012;20(14):4348-55.
2012: Frederick A Valeriote; Taro Amagata; Matthew Edelstein; Tyler A Johnson; Joseph Media; Halina Pietraszkiewicz; Karen Tenney; Phillip Crews
Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program.
Journal of experimental therapeutics & oncology 2012;10(2):119-34.
2010: J Brian Morgan; Fakhri Mahdi; Yang Liu; Veena Coothankandaswamy; Mika B Jekabsons; Tyler A Johnson; Koneni V Sashidhara; Phillip Crews; Dale G Nagle; Yu-Dong Zhou
The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.
Bioorganic & medicinal chemistry 2010;18(16):5988-94.
2010: Tyler A Johnson; Micaela V C Morgan; Natalie A Aratow; Samarkand A Estee; Koneni V Sashidhara; Steven T Loveridge; Nathaniel L Segraves; Phillip Crews
Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products.
Journal of natural products 2010;73(3):359-64.
2010: Jiajiu Shaw; Frederick A Valeriote; Joseph Media; Tyler A Johnson; Taro Amagata; Karen Tenney; Phillip Crews
Development and validation of a rapid method for the detection of latrunculol A in plasma.
Analytical and bioanalytical chemistry 2010;396(5):1741-4.
2009: Tyler A Johnson; Taro Amagata; Koneni V Sashidhara; Allen G Oliver; Karen Tenney; Teatulohi Matainaho; Kenny Kean-Hooi Ang; James H McKerrow; Phillip Crews
The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis.
Organic letters 2009;11(9):1975-8.
2008: Taro Amagata; Tyler A Johnson; Robert H Cichewicz; Karen Tenney; Susan Mooberry; Joseph Media; Matthew Edelstein; Frederick A Valeriote; Phillip Crews
Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges.
Journal of medicinal chemistry 2008;51(22):7234-42.
2008: Tyler A Johnson; Taro Amagata; Allen G Oliver; Karen Tenney; Frederick A Valeriote; Phillip Crews
The unexpected isolation of CTP-431, a novel thiopyrone from the sponge Cacospongia mycofijiensis.
The Journal of organic chemistry 2008;73(18):7255-9.
2007: Joshua D Deschamps; Jeffrey T Gautschi; Stephanie Whitman; Tyler A Johnson; Nadine C Gassner; Phillip Crews; Theodore R. Holman
Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.
Bioorganic & medicinal chemistry 2007;15(22):6900-8.
2007: Tyler A Johnson; Karen Tenney; Robert H Cichewicz; Brandon I Morinaka; Kimberly N White; Taro Amagata; Balanehru Subramanian; Joseph Media; Susan Mooberry; Frederick A Valeriote; Phillip Crews
Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.
Journal of medicinal chemistry 2007;50(16):3795-803.
2006: Rachel N Sonnenschein; Tyler A Johnson; Karen Tenney; Frederick A Valeriote; Phillip Crews
A reassignment of (-)-mycothiazole and the isolation of a related diol.
Journal of natural products 2006;69(1):145-7.
2004: Erika N Segraves; Rachana R Shah; Nathaniel L Segraves; Tyler A Johnson; Stephanie Whitman; Jennifer K Sui; victor kenyon; Robert H Cichewicz; Phillip Crews; Theodore R. Holman
Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.
Journal of medicinal chemistry 2004;47(16):4060-5.
2003: Taro Amagata; Stephanie Whitman; Tyler A Johnson; Chad C Stessman; Christopher P Loo; Emil Lobkovsky; Jon Clardy; Phillip Crews; Theodore R. Holman
Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.
Journal of natural products 2003;66(2):230-5.