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Aby Joiakim

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Althea Elliott; Aby Joiakim; Thomas A Kocarek; Patricia A Mathieu; Zofia Duniec-Dmuchowski; John J Reiners
p-Anilinoaniline enhancement of dioxin-induced CYP1A1 transcription and aryl hydrocarbon receptor occupancy of CYP1A1 promoter: role of the cell cycle.
John J Reiners; Miriam Kleinman; Aby Joiakim; Patricia A Mathieu
The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence.
Joseph A Caruso; Patricia A Mathieu; Aby Joiakim; Hong Zhang; John J Reiners
Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent.

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2012: Althea Elliott; Aby Joiakim; Thomas A Kocarek; Patricia A Mathieu; Zofia Duniec-Dmuchowski; John J Reiners
p-Anilinoaniline enhancement of dioxin-induced CYP1A1 transcription and aryl hydrocarbon receptor occupancy of CYP1A1 promoter: role of the cell cycle.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(5):1032-40.
2009: John J Reiners; Miriam Kleinman; Aby Joiakim; Patricia A Mathieu
The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence.
The Journal of pharmacology and experimental therapeutics 2009;328(3):796-806.
2006: Joseph A Caruso; Patricia A Mathieu; Aby Joiakim; Hong Zhang; John J Reiners
Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent.
The Journal of biological chemistry 2006;281(16):10954-67.
2004: Aby Joiakim; Patricia A Mathieu; Althea A Elliott; John J Reiners
Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome.
Molecular pharmacology 2004;66(4):936-47.
2004: Joseph A Caruso; Patricia A Mathieu; Aby Joiakim; Brendan Leeson; David Kessel; Bonnie F Sloane; John J Reiners
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents.
Molecular pharmacology 2004;65(4):1016-28.
2003: Aby Joiakim; Patricia A Mathieu; Christine M Palermo; Thomas A Gasiewicz; John J Reiners
The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(11):1279-82.
2001: Austin Meng Guo; Aby Joiakim; D T Dudley; John J Reiners
Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated CYP1A1 and CYP1B1 induction by 12-O-tetradecanoylphorbol-13-acetate: role of transforming growth factor beta and mitogen-activated protein kinases.
Biochemical pharmacology 2001;62(11):1449-57.
2000: Austin Meng Guo; Aby Joiakim; John J Reiners
Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002).
Biochemical pharmacology 2000;60(5):635-42.